Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

For centuries, humanists have celebrated and cherished the limitless potential of humankind and its irrepressible spirit. For its efforts to develop rational solutions to human problems rather than invoking supernatural intervention, humanism has been rewarded with a rich and distinguished heritage whose contributors include many of the brightest minds of intellectual history. Advocating reason, critical intelligence, free and objective inquiry, democratic institutions, and moral values based on human experience, humanism stands in steadfast opposition to the moral, political, and social oppression (...) perpetrated by all who would have us swear unquestioned allegiance to authoritarian power, be it temporal or divine. But if humanism is to remain fresh and vibrant, alert and ever vigilant, it must continuously assess and evaluate its goals in light of new experience. In The Question of Humanism, 23 contributors investigate the meaning of humanism today, its range of perspectives, and how humanists can deal with the challenges of contemporary life and those it will face as the new century approaches. This absorbing collection of original essays examines the abundant variety of historical and contemporary humanist philosophies, with special emphasis on the work of Thomas Aquinas, Immanuel Kant, Soren Kierkegaard, Karl Marx, Friedrich Nietzsche, Martin Heidegger, and Michel Foucault. Focusing on the need for an awareness of humanist tradition, these essays offer blunt, progressive self-appraisals to illustrate how humanism will continue to grow as a vital and compelling intellectual force. Featured are essays by Cecil Abrahams, Zygmunt Adamczewski, Samuel Ajzenstat, Martin Andic, Allan Booth, Richard Brown, Michael Cardy, Kenneth Dorter, Richard Francis, David Goicoechea, Danny Goldstick, Calvin Hayes, Marsha Hewitt, Monica Hornyansky, Paul Kurtz, James Lawler, John Luik, Robert McLaughlin, Graeme Nicholson, Zaid Orudjev, Robert Perkins, Charles Scott, and Edward A. Synan. The challenges of the past have served to strengthen humanists' resolve. Humanism, in all of its variations, is now ready for a new era. (shrink)

Among mycologists, questions persist about what entities should be treated as the fundamental units of fungal populations. This article articulates a coherent view about populations of heterokaryotic fungi and the individuals that comprise them. Using Godfrey-Smith’s minimal concept of a Darwinian population, I argue that entities at two levels of the biological hierarchy satisfy the minimal concept in heterokaryotic fungi: mycelia and nuclei. I provide a preliminary answer to the question of how to understand the relation between these two populations. (...) This article contributes to discussions about the nature of biological individuality, organismality, and evolutionary transitions. (shrink)

In this paper I consider whether there can be such things as epistemic reasons for action. I consider three arguments to the contrary and argue that none are successful, being either somewhat question-begging or too strong by ruling out what most epistemologists think is a necessary feature of epistemic justification, namely the epistemic basing relation. I end by suggesting a "non-cognitivist" model of epistemic reasons that makes room for there being epistemic reasons for action and suggest that this model may (...) support moral realism. (shrink)

Eukaryogenesis is widely viewed as an improbable evolutionary transition uniquely affecting the evolution of life on this planet. However, scientific and popular rhetoric extolling this event as a singularity lacks rigorous evidential and statistical support. Here, we question several of the usual claims about the specialness of eukaryogenesis, focusing on both eukaryogenesis as a process and its outcome, the eukaryotic cell. We argue in favor of four ideas. First, the criteria by which we judge eukaryogenesis to have required a genuinely (...) unlikely series of events 2 billion years in the making are being eroded by discoveries that fill in the gaps of the prokaryote:eukaryote “discontinuity.” Second, eukaryogenesis confronts evolutionary theory in ways not different from other evolutionary transitions in individuality; parallel systems can be found at several hierarchical levels. Third, identifying which of several complex cellular features confer on eukaryotes a putative richer evolutionary potential remains an area of speculation: various keys to success have been proposed and rejected over the five-decade history of research in this area. Fourth, and perhaps most importantly, it is difficult and may be impossible to eliminate eukaryocentric bias from the measures by which eukaryotes as a whole are judged to have achieved greater success than prokaryotes as a whole. Overall, we question whether premises of existing theories about the uniqueness of eukaryogenesis and the greater evolutionary potential of eukaryotes have been objectively formulated and whether, despite widespread acceptance that eukaryogenesis was “special,” any such notion has more than rhetorical value. (shrink)

It is strange to write for the pages of this journal a statement which will not come under the eye of its founding editor, Sheldon Sacks. For nearly five years everything that appeared in Critical Inquiry—articles, critical responses, editorial comments—was a matter of painstaking and passionate concern to Shelly Sacks. With a flow of questions and suggestions and a talent for unabashed cajolery, he generated articles and rejoinders to those articles. He worked tirelessly in editorial consultation and correspondence with contributors, (...) especially young writers, helping them to discover the best way of giving form to their ideas. Among the essays submitted to this journal he searched eagerly, even anxiously, for those which seemed, in his words, "right for C.I." What was right for C. I. was never, for Shelly Sacks, a cut-and-dried choice. In his own intellectual life, in his teaching and writing, he delighted in arguing important general questions: theories of representation in the arts, points of possible intersection between linguistic science and literary criticism, the interplay of social forces and cultural expressions. Not surprisingly, in reconnoitering for Critical Inquiry, he found special satisfaction in identifying writers who shared his passion for reexamining fundamental topics in the intellectual disciplines. If such writers made their case forcefully, so much the better: in choosing an essay for publication he assessed its capacity to stimulate interesting counterargument. At no time, however, did Shelly Sacks confuse his own beliefs with the nature of intellectual discourse. As an editor he was hospitable to writers whose premises he questioned and whose conclusions he deplored. Nor did Shelly attempt to achieve a spurious catholicity by following a quiet quota system designed to give each major line of interpretation—deconstructionist, Marxist, psychoanalytic, what have you—an occasional airing in Critical Inquiry. For Shelly each article stood on its own ground: if its author dealt responsibly and freshly with an interesting problem, that was enough. And, along with his commitment to theoretical inquiry, he responded warmly to the personal, the offbeat, the idiosyncratic. He regarded the feature Artists on Art, for example, as a central element in our design. As an editor Sheldon Sacks was above all a shaper. He labored to find and suggest connections in the phenomena of intellectual life. Even the construction of a table of contents for a typical Critical Inquiry issue became for him an opportunity to influence the reader's experience of what we offered. The eminence of an author or the allure of a title were put to one side as Shelly sought to orchestrate, through placement, a kind of intellectual counterpoint from one essay to another. Unheard melodies, doubtless, for many of us, but for Shelly real and sustaining. In this valedictory note we have spoken of Sheldon Sacks' editorial accomplishment—in our friendly view, a very distinguished one—rather than of the personal qualities which made working alongside him an exhilarating experience. We should report, however, that for more than half the life of this journal Shelly was ill and knew that the time available to him was likely to be relatively brief. Faced with this diminishing perspective, he did not—indeed it is more accurate to say he could not—moderate his involvement with the life of this journal. At his death, as at the launching of this enterprise, he held to the high ambition that Critical Inquiry encourage comeliness, vigor, and continuity in the discourse of our time. The appropriate "critical response" to this great loss is that Sheldon Sacks’ editorial colleagues, and our publisher, the University of Chicago Press, pledge whatever talents and energies we possess to the continuing life of the journal he imagined and brought into being. (shrink)

Improvement in performance after the end of the training session, termed “Offline improvement,” has been shown in procedural learning tasks. We examined whether Offline improvement in learning a novel orthography depends on the type of reading instruction. Forty-eight adults received multisession training in reading nonsense words, written in an artificial script. Participants were trained in one of three conditions: alphabetical words preceded by direct letter instruction (Letter-Alph); alphabetical words with whole-word instruction (Word-Alph); and nonalphabetical (arbitrary) words with whole-word instruction (Word-Arb). (...) Offline improvement was found only for the Letter-Alph group. Moreover, correlation with a standardized measure of word reading ability showed that good readers trained in the Letter-Alph group exhibit greater Offline improvement, whereas good readers trained in the Word-Arb group showed greater Within-session improvement during training. These results suggest that different consolidation processes and learning mechanisms were involved in each group. We argue that providing a short block of direct letter instruction prior to training resulted in increased involvement of procedural learning mechanisms during training. (shrink)

We look at the problem of revising fuzzy belief bases, i.e., belief base revision in which both formulas in the base as well as revision-input formulas can come attached with varying degrees. Working within a very general framework for fuzzy logic which is able to capture certain types of uncertainty calculi as well as truth-functional fuzzy logics, we show how the idea of rational change from “crisp” base revision, as embodied by the idea of partial meet (base) revision, can be (...) faithfully extended to revising fuzzy belief bases. We present and axiomatise an operation of partial meet fuzzy base revision and illustrate how the operation works in several important special instances of the framework. We also axiomatise the related operation of partial meet fuzzy base contraction. (shrink)

This is the first book to deal with both the psychological and neurobiological mechanisms in appetites for drugs, food, sex, and gambling, and considers whether there are common factors between them. The authors approach this by looking at the bases of both normal and abnormal appetites in humans. The focus on human appetites will be of great interest to psychologists and clinicians alike.The EBBS Publications Series is designed to provide researchers and students with authoritative, topical reviews of major areas in (...) the brain and behaviour sciences. Each volume will include specially commissioned and edited chapters by leading researchers, presented in a lively and accessible style. (shrink)

The ethical practices of credit rating agencies, particularly following the 2008 financial crisis, have been subject to extensive analysis by economists, ethicists, and policymakers. We raise a novel issue facing CRAs that has to do with a problem concerning the transmission of epistemic status of ratings from CRAs to the beneficiaries of the ratings, and use it to provide a new challenge for regulators. Building on recent work in philosophy, we argue that since CRAs have different stakes than the beneficiaries (...) of the ratings in the ratings being accurate, what counts as knowledge concerning credit risk for a CRA may not count as knowledge for the beneficiary. Further, as it stands, many institutional investors are bound by law to make some of their investment decisions dependent on the ratings of officially recognized CRAs. We argue that the observation that the epistemic status of ratings does not transmit from CRAs to beneficiaries makes salient a new challenge for those who think current regulation regarding the CRAs is prudentially justified, namely, to show that the harm caused by acting on a rating that does not have epistemic status for beneficiaries is compensated by the benefit from them acting on a CRA rating that does have epistemic status for the CRA. Unlike most other commentators, therefore, we offer a defeasible reason to drop references to CRAs in prudential regulation of the financial industry. (shrink)

This volume looks outward to the twenty-first century and to the dynamics of this first truly global age. It asks the fundamental question: how might human societies live? In contrast to the orthodoxies of academic Philosophy and International Relations in much of the twentieth century, which marginalised or rejected the study of ethics, the contributors here believe that there is nothing more political than ethics, and therefore deserving of scholarly analysis. By exploring some of the oldest questions about duties and (...) obligations within and beyond humanly constructed boundaries, the essays help us ponder the most profound question in world politics today: who will the twenty-first century be for? (shrink)

The connections between nonmonotonic reasoning and belief revision are well-known. A central problem in the area of nonmonotonic reasoning is the problem of default entailment, i.e., when should an item of default information representing “if θ is true then, normally, φ is true” be said to follow from a given set of items of such information. Many answers to this question have been proposed but, surprisingly, virtually none have attempted any explicit connection to belief revision. The aim of this paper (...) is to give an example of how such a connection can be made by showing how the lexicographic closure of a set of defaults may be conceptualised as a process of iterated revision by sets of sentences. Specifically we use the revision method of Nayak. (shrink)

Abstract: In this article, I consider some of the similarities and differences between deontologism in ethics and epistemology. In particular, I highlight two salient differences between them. I aim to show that by highlighting these differences we can see that epistemic deontologism does not imply epistemic internalism and that it is not a thesis primarily about epistemic permissibility . These differences are: (1) deontologism in epistemology has a quasi -teleological feature (not shared with moral deontologism) in that it does not (...) require that one abide by epistemic duties for the sake of (and not merely in accordance with) those very duties; and (2) in ethics, the relevant options we speak of are whether someone acts or does not act; in epistemology, we have an analogous further option: we can speak of whether someone believes that p , fails to believe that p , or withholds judgment about that p. (shrink)

Questions of identity involve the attempt to determine what exactly makes a person or thing what it is—what makes Tara Tara or what makes Charming Charming? The chapter analyzes Ricoeur's ideas on personal identity to see if they can help us make sense not only of Tara's identity, but also of how SAMCRO and some of its members maintain their identity across time. Ricoeur describes how we weave the two types of identity, sameness and selfhood, together to form a narrative, (...) a story that allows us to understand how we are able to preserve our identities through time. Narrative identity links up a person's character and the anchor of promise keeping, the practice of keeping one's promises. Finally, the chapter talks life history of John Teller, which is delicately intertwined with the fate of every member of SAMCRO. (shrink)

Neither the pathogenesis nor the aetiology of Down's syndrome (DS) are clearly understood. Numerous studies have examined whether clinical features of DS are a consequence of specific chromosome 21 segments being triplicated. There is no evidence, however, that individual loci are responsible, or that the oxidative damage in DS could be solely explained by a gene dosage effect. Using astrocytes and neuronal cultures from DS fetuses, a recent paper shows that altered metabolism of the amyloid precursor protein and oxidative stress (...) result from mitochondrial dysfunction.1 These findings are consistent with considerable data implicating the role of the mitochondrial genome in DS pathogenesis and aetiology. BioEssays 24:681–684, 2002. © 2002 Wiley Periodicals, Inc. (shrink)

A defense of the Dynamical Hypothesis against the charge that one of its major supports, the argument from time, is rotten.

The greatest intensity of “live” life is captured from as close as possible in order to be borne as far as possible away. Jacques Derrida. Echographies of Television . Rainer Ganahl has made a study of studying. As part of his extensive autobiographical art practice, he documents and presents many of the ambitious educational activities he undertakes. For example, he has been videotaping hundreds of hours of solitary study that show him struggling to learn Chinese, Arabic and a host of (...) other languages. The stacked boxes of tapes are then presented like minimalist monoliths, dense archives of effort. About fifteen years ago, Ganahl began photographing the lectures that he attends. At the time, he hadn’t seen anyone else doing it, so besides his spare selection of images of the speaker and the audience, much of the time the lectures would just pass into memory, undocumented, or recorded in writing alone. Since then, he has felt the transition to digital cause a significant shift in his process. At the same time, he has seen the habit become ubiquitous as others photograph, record, and videotape the lectures all around him. In keeping with the theme of this inaugural issue of continent. , can we propose each small grouping of photographs that result an isthmus stretching between two disparate bodies of mind? The first being the body of the lecture as spelled out in the title of each work – the experience of the event in all its constituent parts. The second is the body of the recipient, the listener, in this case an artist, who plays a minimal role just beyond the prescripted behavior of sitting and listening. He uses a gesture of documentation to draw a line between himself and the event, creating an artwork. Františka + Tim Gilman: As we mentioned before, the theme of the magazine for this issue is "isthmus." It seems like a very good way into your work, and it leads us to ask what connection you see between your photographs of the lecture and the lecture itself? Rainer Ganahl: The relationship is of course a concrete, pictorial one, or if you want a mimetic one but also an abstract one because the photographs carry the title of the lecture, the names of the lecturers, the site, the institution and the time of the lecture. Photos are fixed moments of time and can reproduce images displayed and reproduce visuals presented at a moment but they don’t come with time based recordings that video or sound takes are offering. What remains of a lecture is usually just the memory, some notes and all the announcements of it. In my case I end up with a visual product I declare as my artwork. It might not differ from any snapshot taken by any other student or member of the audience but I do this in a semi-systematic way with certain rules and procedures I have set up. While I am at a lecture I am mainly focusing on the lecture itself. Last night I went to one of Slavoj Žižek which demanded quite some concentration. I even was asking him a question at the end. I took photos as well but still didn’t lose track of the lecture. I didn’t walk around, I was not preoccupied by where I was sitting and what light I was having like some of the other photographing and filming people in the room who came and left, moved around and tried to capture him from this and that angle, from close and far. I just sat there and concentrated on the lecture and yet managed to take about 30 or so images of him, the public around me and of the film clips he presented. Once the lecture is over the story changes: it all becomes a question of the images, their selection, their visual qualities, their labeling and archiving. The function of the images also change: not only do they stand for an intellectual event in a row of lectures that become part of my intellectual history within many possible such histories but they also have to function as art, something not everybody else with images of lecturers demands of their images. This is my specific claim as an artist to impose them as artworks. And as with all artistic propositions the offer can be accepted or rejected. I basically spend my life trying to do exactly that: making what I declare as art, offering something to anybody interested in it as my art, an offer that is not and will never be accepted as such by all people. F+T: What are your criteria for selection, i.e. how do you choose which lectures to photograph, by lecturer, by topic, or do you photograph any and every lecture you can? RG: As everything in my life, I go by my interest which is the result of many factors. If I am aware of a lecturer, read his books or appreciate his works my interest of attending his much higher than if I am not aware of it. I usually don’t go to lecturers simply based on their subjects—something that can happen of course, if the subject, the title of the lecture is promising or at the heart of my interest. Sometimes I also wait for years to get a change to photograph certain people but I do that in a very low-level “keep your ears up” mentality and not in a systematic scanning of all channels and possibilities. I do not go into philosophy departments and photograph everybody teaching there. I go with the flow—and unfortunately a great deal of great talks I also miss because I hear too late of them. Often, I also stumble into them by traveling, by getting emails from friends and by simply being in the right spot at the right time. Somehow you could look at my lecture par cours as some kind of loose intellectual flâneurism . If you know of interesting lectures and events, please, let me know. F+T: Is your selection of images more of a production or post-production method? That is, do you take a lot of photos and select only a few images from each lecture, or do you take them very selectively? Do you have a particular methodology for the selection of images? RG: This all changed a bit with the arrival of digital photography. In the beginning I had to pay a lot of money for film developing. Hence, I was taking either one role - 36 images - or half a role - 13 images - depending on who talked and whether they projected images. With the unlimited capacity of digital imaging I easily end up between 30 and 150 images of one event still depending of whether images are presented or not. In the first years of that project when I wasn’t fully aware yet of what I was doing, I printed at least 2 images of any lecture and sometimes three or even four, a choice that was also constrained by costs. But again, since I have a web site and since images can easily be selected and presented on my web site without generating remarkable costs I have now more and more pain to reduce them to less than ten or eight images for an event. Now, before I have them printed which really is expensive, I can present them already as artwork on my web site without any immediate costs. Thus the economic factor is at the end of the chain which enables me to be more ‘generous’ and include more images. Over the last years I have been mostly selecting at least four photographs for a lecture unit but recently also as many as ten. But so far only one set above four images has been actually printed and sold. What might sound even more shocking is the likely fact that if a curator or a collector demands me to reduce the number of images due to costs, I might compromise at this current stage if the images have not been yet printed or published outside my own web site. This means that to a certain degree any selection that has only seen publication on my web site and not yet been produced runs the risk to change in numbers of images included. Needless to say, I am the last one that finally makes a decision and I do honor all given earlier decision if those were final. F+T: How do you feel the act of photographing the lecture affects your reception of the contents of the lecture? And your recollection afterwards, do you remember the lecture more having photographed it, or just having sat and listened? RG: As mentioned above, I get very little distraction from photographing since I can multitask well and do not obsess about the quality of the image: I photograph from where I am and listen with my ears and not my eyes. I am not sure whether the images serve as a mnemonic devise to the content of the lecture if there are no images involved but they at least remind me that the lecture existed, the title of the lecture and the name of the people and institutions involved. The titles of the hundreds of lectures I took during the past 15 years can also be read as an essay of theoretical life in that period. This will be come more and more visible as time passes by. These images age much better than I do. F+T: You mentioned at the outset of our discussions that you started this practice some time ago and have seen the practice of photographing lecturers become more commonplace. Why do you think that this shift has taken place? RG: The answer is very simple. Photographing is now free of any charge and hence omnipresent. You buy a phone or any other personal digital assistant and it has a camera integrated in it whether you want it or not. There is no need to develop images and there is no hassle to keep images, to distribute images, to organize images and save them. It is all virtual, not creating any costs and doesn’t require any efforts. You don’t spend twenty dollars for photo-developing anymore, you don’t need to walk anymore to your pharmacy or your photo shop to drop off and return to pick up and pay. You don’t need to go to the post office to send somebody a picture. You have a program like Photoshop already built into your camera. Photographing is now a thing for everybody—with functioning cameras made for two year olds. It is technically now nearly impossible to make bad images. The image quality is virtually guaranteed by cheap, high performing, mini-computers packed into miniscule cameras. With all these technological changes, we are undergoing now a cultural paradigm shift that includes permanent recording (not only still image taking) of everything. I wonder even whether babies are just born to be photographed—at least a process where the first photograph is right there. What is interesting now, is how the law is trying to catch up. I am experiencing and expecting more restrictions on photographing and recording—something already in place in many museums and in certain galleries—as the recording devices become more and more invisible and undetectable. It is an interesting cat and mouse play and will end up with some of us that are photographing the world around us in court. The world has become very transparent and everybody is contributing to it with social networking technologies—like twitter and Facebook—that are designed to monitor and communicate every step we make in our lives. F+T: Why did you start the practice? As a way to remember, or to capture the experience of the lecture and the environment there? RG: A couple of years earlier I started to photograph my own reading seminars as part of my art work with results that surprised me positively. I really liked these images of students and people discussing heavy non-fiction with me. The reading seminars justified this kind of pictorialism. Then in 1995 I had the chance to attend an entire seminar by Edward Said entitled “The Representation of Intellectuals at Columbia University,” which really gave me the idea to start this series. Why not also photograph these lectures I visit all the time since this really is a way of representing intellectuals? F+T: The constellation of images and the title seem like a kind of portrait, do you agree? If so, is it a portrait of the speaker, of yourself, or of the event? RG: Well, to follow up on the previous question the lectures are more than just portraits of lecturers since I include not only the speakers but also the audience, an audience that is not named or specifically highlighted as is the speaker. So if we stick with the metaphor of the portrait we would have to extend it also to the environment, the class room, the lecture hall, the arrangements of seats or benches, tables, lecture stands and other stuff typically seen on my images. Often the walls are decorated or even tagged with graffiti or posters and other stuff. There is a big difference between a small seminar room at the English Department of Columbia University, full with books and cabinets and a lecture room at a Paris or Frankfurt university that accommodates 50 to 150 people. We should, maybe, also distinguish between lectures that are one time events—mostly open to the public, free of charge or paid—and events that are weekly, closed to the public and held mostly in universities that can cost fortunes or be paid by the State as it is still predominantly the case in continental Europe. All this, of course, is not necessarily announced in the title of the lecture and is subject to information that isn’t visible on the images. To a certain degree we see also portraits of a general privilege when it comes to the public of certain institutions that are highly selective and extremely costly without forgetting that most of the lectures are dealing with theory, art, philosophy and other highbrow subjects. In general, I would say we see very little if we don’t know already what’s going on, who the lecturer, the institutions, the context are in which we subsequently can zoom into variants like sexual, racial, or age-related make-up without ignoring clothing fashions, hair styling, body mannerisms, gadgets and stuff. F+T: Do you see a relation between this body of work and your other work, for example your language studies? RG: Everything I do is “unfortunately” related. I say unfortunately because this makes my work not so easy to grasp. The relationship to the language studies is relatively clear since both are originally grounded in the domain of education and knowledge production. Nearly all my work comes across that nexus where knowledge and power are addressed. I was at one point wondering what the relationship was to some of my earlier indexical work where I was happy alone with footnotes from books painted on the walls: I came to understand that both are just different manifestations of knowledge and information. F+T: Do you foresee continuing the series indefinitely, or is there an end to it? RG: I think that I will continue this series indefinitely or to be more precise, as long as I go listen to lectures and want to learn something which brings me to your previous question: What do the reading seminars, language studies, historical research and lecture hopping have in common: I learn something. Further Reading Rainer Ganahl’s website William Kaizen. “ Vulgar Politics .” art&education . April 2009. Web. Smith, Roberta. “ Rainer Ganahl: ‘Language of Emigration & Pictures of Emigration .’” New York Times April 23 2010. Web. (shrink)

Improving the treatment of life threatening emergency illness or disease requires that new or novel therapies be assessed in clinical trials. As most subjects for these trials will be incapacitated there is some controversy about they might best protected whilst still allowing research to continue. Recent European and UK clinical trials legislation, which has effectively stopped research into emergency conditions, is discussed. Possible changes to these regulations are proposed.

Some individuals have a neurogenetic vulnerability to developing strong facilitation of ingestive movements by learned configurations of biosocial stimuli. Condemning food as addictive is mere polemic, ignoring the contextualised sensory control of the mastication of each mouthful. To beat obesity, the least fattening of widely recognised eating patterns need to be measured and supported.

The author reflects upon the notions of personal memory, collective memory, myth, and evolved memory within her lived experience of Risdon Vale. These interrelated forms of memory influence understanding of place and sense of place. Personal memories corroborate and collaborate with intersubjective memories to inform collective memory. Both personal and collective memories are held within a fusion of cultural myths. Evolved memory binds us deeply within the history of the earth and the evolution of life. Risdon Vale provides fertile ground (...) for considerations of place and memory. This former public housing suburb is adjacent to Risdon Cove, the site of first occupation by the British in 1803 and the site of the first massacre of Aboriginal Tasmanians in 1804. (shrink)

Background: Moral distress is the inability to do the right thing due to institutional constraints. The Measure of Moral Distress – Healthcare Professionals (MMD-HP) measures this phenomenon and has extensively explored moral distress among nurses. There are limited large-scale research studies using the MMD-HP to identify levels of moral distress across multiple healthcare professionals (HPs) and settings. Research question: What are the overall levels of moral distress among HPs? Research design: A quantitative, exploratory, cross-sectional study of HPs in a healthcare (...) system using the MMD-HP. Participants and research context: Eligible participants included HPs ( N = 8,206) working in all inpatient and outpatient units and centers in a multi-site healthcare system located in the Southeastern United States. Ethical considerations: The Institutional Review Board provided approval for this research. A survey preamble supplied information within the learning management system and consent was presumed with survey completion. Findings: A total of 3,561 HPs completed the MMD-HP. The top three morally distressing items included compromised patient care due to inadequate resources, caring for more patients than is safe, and low quality of patient care due to poor team communication. Intensive care unit (ICU) areas had significantly greater moral distress than all other areas ( p < 0.001). Formal leaders had the greatest moral distress ( p < 0.001). Mixed-acuity and medical-surgical HPs accounted for 22.8% of those who reported considering leaving their current position due to moral distress. Nurses represented 42.2% of those considering leaving their current position due to moral distress. Conclusions: This study uniquely identified that formal leaders and HP participants in the ICU setting had the greatest moral distress. Exploring moral distress is imperative for healthcare systems to decrease turnover, improve engagement, and the quality of patient care. (shrink)

Types of sensory receptor can only be identified by multidimensional discrimination of a familiar version of a sensed object from variants that disconfound putative types. By that criterion, there is as yet no evidence against just the four classic types of gustatory receptor, for sodium salts, alkaloids, sugars, and proton donors.

This book examines how the academic discipline of International Relations has conceptualised the world historical crisis that has shaped world affairs between the end of the First World War and the end of the 1990s. A distinguished group of contributors trace the development of the subject through the main historical periods and in relation to key debates: ethics, power and nationalism; conditions of peace; law and peaceful change; and globalization. It provides the most comprehensive survey of the discipline’s past and (...) the key issues to be faced in the future. (shrink)

Westphal wished to transpose lines 88–90 and 93–5 of the Supplices. This transposition has been supported recently by R. D. Dawe , by Holger Friis Johansen in C. & M. xxvii , 43–4 , and by Sir Denys Page . However, the transposition gains little support from a careful examination of the language and context of the passage, as I shall now proceed to demonstrate. I discussed the whole passage previously in my article ‘Aeschylus Supplices 86–95’, Classical Philology, 1 , (...) 21–5, and much of my argument can be found in that earlier article. (shrink)

Introduction -- "Mediating estrangement: a theory for diplomacy," review of International Studies (April, l987), 13, pp. 91-110 -- "Arms, hostages and the importance of shredding in earnest: reading the national security culture," Social Text (Spring, 1989), 22, pp. 79-91 -- "The (s)pace of international relations: simulation, surveillance and speed," International Studies Quarterly (September 1990), pp. 295-310 -- "Narco-terrorism at home and abroad," Radical America (December 1991), vol. 23, nos. 2-3, pp. 21-26 -- "The terrorist discourse: signs, states, and systems of (...) global political violence," World Security: Trends and Challenges at Century's End, ed. M. Klare and D. Thomas, St. Martin's Press (1991), pp. 237-265. -- "S/N: international theory, balkanisation, and the new world order," Millennium Journal for International Studies (Winter 1991), vol. 20, no. 3, pp. 485-506 -- "Cyberwar, videogames, and the Gulf War syndrome," Antidiplomacy: Spies, Terror, Speed and War (Cambridge, Ma and Oxford, UK, 1992), pp. 173-202 -- "Act IV: fathers (and sons), mother courage (and her children), and the dog, the cave, and the beef," in Global Voices: Dialogues in International Relations, ed. James N. Rosenau (Boulder, Co and Oxford, Uk: Westview Press, 1993), pp. 83-96 -- "The value of security: Hobbes, Marx, Nietzsche and Baudrillard," in the Political Subject of Violence, ed. G.M. Dillon and David Campbell, Manchester University Press (1993), pp. 94-113 -- "The C.I.A., Hollywood, and sovereign conspiracies," Queen's Quarterly (Summer 1993), vol. 100, no. 2, pp. 329-347 -- "Great men, monumental history, and not-so-grand theory: a meta-review of Henry Kissinger's diplomacy," Forum review article, Mershon International Studies Review (april 1995), vol. 39, no. 1, pp. 173-180 -- "Post-theory: the eternal return of ethics in international relations," New Thinking in International Relations Theory, eds. Michael Doyle and John Ikenberry (New York: Westview Press, 1997), pp. 55-75 -- "Cyber-deterrence," Wired (September 1994), 2.09., p. 116 (plus 7 pages) -- "Global swarming, virtual security, and Bosnia," the Washington Quarterly (Summer 1996), vol. 19, n0. 3., pp. 45- 56 -- "The simulation triangle," 21c (issue 24, 1997), pp. 19-25 -- "Virtuous war and hollywood," the Nation (3 april 2000), pp. 41-44 -- "Virtuous war/virtual theory," International Affairs (fall, 2000), pp. 771-788 -- "Hedley Bull and the case for a post-classical approach," International Relations at LSE: a History of 75 Years (London: Millennium Publishing Group, 2003), pp. 61-87. "the illusion of a grand strategy, op-ed," the New york Times, may 25, 2001 -- "In terrorem: before and after 9/11," Worlds in Collision, eds. Ken Booth and Tim Dunne (New York: Palgrave Macmillan, 2002), pp. 101-116 -- "The question of information technology in international relations," Millennium Journal of International Studies (vol. 32, no. 3, 2003), pp. 441-456 -- "The illusion of a grand strategy," op-ed, the New York Times, may 25, 2001. (shrink)