Drawing on a landscape analysis of existing data-sharing initiatives, in-depth interviews with expert stakeholders, and public deliberations with community advisory panels across the U.S., we describe features of the evolving medical information commons. We identify participant-centricity and trustworthiness as the most important features of an MIC and discuss the implications for those seeking to create a sustainable, useful, and widely available collection of linked resources for research and other purposes.

Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

Este artículo examina determinados elementos de la filosofía de Michel Henry que pueden entenderse como aportes a una crítica de las categorías del valor. Con este fin, el punto de partida consiste en continuar y abrir nuevas posibilidades de discusión en torno a un vínculo que ya ha sido explorado en artículos recientes: la relación entre las ideas del fenomenólogo francés con determinadas interpretaciones actuales sobre la Modernidad y el capitalismo. Por otro lado, estas páginas pueden servir como reseña (...) e invitación a visitar uno de los aspectos menos conocidos de la obra de Michel Henry: su interpretación de la obra de Marx desde las nociones de individuo, praxis y subjetividad. (shrink)

Iván Ortega Rodríguez livre une contribution où M. Henry est mis en confrontation avec Patočka, notamment sur la corrélation entre la vie et le monde, autrement dit sur l’« a priori de corrélation ». Comme le rappelle l’auteur de cette étude, tant Patočka que M. Henry adoptent cette corrélation a priori comme point de départ, et donc eu égard aux questions portant respectivement sur l’apparaître, sur ce qui apparaît et sur cette vie subjective qui semble devoir accompagner toute (...) donation. Aussi Iván Ortega Rodríguez soutient-il que tout semble se jouer entre M. Henry et Patočka dans leur conception de l’apparaître. Autant la donation henryenne nous invite à nous singulariser dans notre expérience selon le pathos de la vie auto-affective, autant elle nous invite chez Patočka à sortir hors de nous-mêmes selon la priorité accordée à l’aspect de « champ » que nous trouvons dans le se-montrer, là où se place tout ce qui est donné. (shrink)

En el presente artículo se hace una descripción de las variables fenomenológicas del movimiento, la ipseidad y la sensibilidad que propone la filosofía de Michel Henry. A partir de esta lectura se profundiza en el papel epistémico que ejerce la corporeidad, como horizonte de sentido para una ‘fenomenología de la vida material’.

Henry Allison is one of the foremost interpreters of the philosophy of Kant. This new volume collects all his recent essays on Kant's theoretical and practical philosophy. All the essays postdate Allison's two major books on Kant, and together they constitute an attempt to respond to critics and to clarify, develop and apply some of the central theses of those books. Two are published here for the first time. Special features of the collection are: a detailed defence of the (...) author's interpretation of transcendental idealism; a consideration of the Transcendental Deduction and some other recent interpretations thereof; further elaborations of the tensions between various aspects of Kant's conception of freedom and of the complex role of this conception within Kant's moral philosophy. (shrink)

So considered, Hume is viewed as a naturalist, whose project in the first three parts of the first book of the Treatise is to provide an account of the ...

CHAPTER I GENERAL ACCOUNT OF THE SUBJECT THERE is some difficulty in defining the subject of Ethics in a manner which can fairly claim general acceptance ...

"By linking Wittgenstein with Derrida, Staten suggests that the intellectual relevance of deconstruction is wider than the English-speaking public has...

There is compelling evidence that pain experience is influenced by cognitive states. We explore one specific form of such influence, namely placebo analgesia, and examine its relevance for the cognitive penetration debate in philosophy of mind. We single out as important a form of influence on experience that we termradical cognitive penetration,and argue that some cases of placebo analgesia constitute compelling instances of this phenomenon. Still, we urge caution in extrapolating from this to broader conclusions about cognitive penetration in perceptual (...) experience. Instead, we suggest that the cognitive penetration of pain raises distinctive psychological, epistemological, and ethical issues. (shrink)

INTRODUCTION THE SEEMING CONTINGENCY OF THE QUESTION CONCERNING THE BODY AND THE NECESSITY FOR AN ONTOLOGICAL ANALYSIS OF THE BODY When we disclose and..

Thoreau's political writing is intensely personal and direct. Both his life and work focus uncompromisingly on the question 'how should I live?', and for Thoreau, no element of day-to-day existence is left untouched by moral and political issues. This edition of Thoreau's political essays includes 'Civil Disobedience', selections from Walden, 'Life Without Principle', and the anti-slavery addresses, such as 'Slavery in Massachusetts'. In her introduction, Nancy L. Rosenblum places the essays in the context of Thoreau's life of self-examination, and the (...) debates about the abolition of slavery, and she analyses the themes of citizenship and resistance that have made Thoreau an enduring influence in political philosophy and practice. (shrink)

En reposant la question fondamentale de la phénoménologie, et de la philosophie — la question de la donation —, en interprétant celle-ci non plus seulement, selon la pensée traditionnelle de l'Occident, comme apparition dans un monde mais comme l'étreinte invisible de la vie en son propre pathos, la phénoménologie matérielle soulève des problèmes nouveaux et paradoxaux. Trois d'entre eux font l'objet des présentes études : 1 / La matière de la conscience, l'Impression, n'est plus un contenu opaque attendant l'éclaircissement de (...) la forme intentionnelle, ne s'exhibant que dans l'Ek-stase du Temps : elle accomplit la Révélation en elle-même, dans sa chair affective. Au lieu de définir une discipline mineure, vite oubliée, la phénoménologie hylétique — matérielle — dessine la tâche de l'avenir. 2 / La possibilité de connaître la vie invisible donne son sens au problème de la méthode phénoménologique et exige que celle-ci soit repensée entièrement. 3 / La relation à autrui change elle-même de nature si, avant de pouvoir être reconnue au milieu du monde, elle prend corps dans la vie où naissent tous les vivants, l'autre aussi bien que moi-même — si elle est un « pathos-avec ». — Michel Henry —. (shrink)

The science of consciousness has made great strides in recent decades. However, the proliferation of competing theories makes it difficult to reach consensus about artificial consciousness. While for purely scientific purposes we might wish to adopt a ‘wait and see’ attitude, we may soon face practical and ethical questions about whether, for example, agents artificial systems are capable of suffering. Moreover, many of the methods used for assessing consciousness in humans and even non-human animals are not straightforwardly applicable to artificial (...) systems. With these challenges in mind, I propose that we look for ecumenical heuristics for artificial consciousness to enable us to make tentative assessments of the likelihood of consciousness arising in different artificial systems. I argue that such heuristics should have three main features: they should be (i) intuitively plausible, (ii) theoretically-neutral, and (iii) scientifically tractable. I claim that the concept of general intelligence — understood as a capacity for robust, flexible, and integrated cognition and behavior — satisfies these criteria and may thus provide the basis for such a heuristic, allowing us to make initial cautious estimations of which artificial systems are most likely to be conscious. -/- . (shrink)

First published in 1993. Routledge is an imprint of Taylor & Francis, an informa company.

It is argued that the principles of classical physics are inimical to the development of a satisfactory science of consciousness The problem is that insofar as the classical principles are valid consciousness can have no e ect on the behavior and hence on the survival prospects of the organisms in which it inheres Thus within the classical framework it is not possible to explain in natural terms the development of consciousness to the high level form found in human beings In (...) quantum theory on the other hand consciousness can be dynamically e cacious quantum the ory does allows consciousness to in uence behavior and thence to evolve in accordance with the principles of natural selection However this evo lutionary requirement places important constraints upon the details of the formulation of the quantum dynamical principles.. (shrink)

This is a reprint of the classic work by Henry Churchill King, "The Seeming Unreality of the Spiritual Life."At Oberlin College from 1884, he taught in mathematics, philosophy, and theology. From 1902 to 1927, he was president of the college. With a tenure of 25 years, is Oberlin's longest-serving president. In 1919, he served on the King-Crane Commission, whose recommendations on the fair and just disposition of non-Turkish areas of the Ottoman Empire might, had they been followed, would have (...) averted many of the tragedies that have come to pass in the Middle East since that time. The findings of that commission, suppressed until 1922, were finally made public in the King-Crane Commission Report and shed tremendous light on the wishes of the indigenous peoples of the region, as to who would be entrusted with the various mandates, the future of Palestine, and other vital issues.He was prominent in the councils of the Congregational Church and a moderator (1919-21) of its National Council as well as chairman (1921-27) of the Congregational Foundation for Education. (shrink)

En este artículo, partiendo de la crítica que hace Gadamer en Verdad y Método al concepto de autosignificatividad de la percepción de Richard Hamann, queremos mostrar lo abstracto de la pretensión de una percepción pura y cómo ella siempre remite a generalidades más amplias. Para reforzar esta perspectiva recurrimos a Martin Heidegger en Ser y tiempo con el fin de entender el concepto de ser-a-la-mano y todo el conjunto de remisiones que lo conforman. Con éste concluiremos sobre la necesidad de (...) suponer contextos relacionales más amplios y fundamentales como base de abstracciones particulares como la obra de arte y el dato empírico en la ciencia. Critique of pure perception. A phenomenological and hermeneutic approach In this article, based on the critique of Gadamer in Truth and Method to Richard Hamman’s concept of “autosignificance” of perception, we want show how abstract the assertion of a pure perception is and how it always refers to broader generalities. To reinforce this perspective we turn to Martin Heidegger’s Being and time in order to understand the concept of ready-to-hand and the whole set of remissions it comprises. With this we conclude on the need to assume broader, more fundamental relational contexts as the basis of particular abstractions such as works of art and the empirical datum in science. (shrink)

The powerful qualities view of properties is currently enjoying a surge in popularity. Recently, I have argued that the standard version of the view is no different from a rival view: the pure powers position. I have also argued that the canonical version of the powerful qualities view faces the same problem as the pure powers view: the dreaded regress objection. Joaquim Giannotti disagrees. First, Giannotti thinks that the standard version of the powerful qualities view can be differentiated from the (...) pure powers view. Second, Giannotti argues that the powerful qualities view is not susceptible to the regress objection. Third, he argues that there is another reasonable version of the powerful qualities view available, which makes use of the notion of ‘aspects’. In this note, I respond to Giannotti. I argue that all three of Giannotti’s arguments are unsuccessful. (shrink)

It is emphasized that a many-worlds interpretation of quantum theory exists only to the extent that the associated basis problem is solved. The core basis problem is that the robust enduring states specified by environmental decoherence effects are essentially Gaussian wave packets that form continua of non-orthogonal states. Hence they are not a discrete set of orthogonal basis states to which finite probabilities can be assigned by the usual rules. The natural way to get an orthogonal basis without going outside (...) the Schroedinger dynamics is to use the eigenstates of the reduced density matrix, and this idea is the basis of some recent attempts by many-worlds proponents to solve the basis problem. But these eigenstates do not enjoy the locality and quasi-classicality properties of the states defined by environmental decoherence effects, and hence are not satisfactory preferred basis states. This core problem is obscured by approaches that treat the universe as a quantum computer, but it needs to be addressed and resolved before a many-worlds-type interpretation can be said to exist. (shrink)

Here I discuss the basic elements, major stages, and completion of progressive evolution. The cosmic world of self-realization is based on extensive self-development within a closed contour: temporal counter-transitions of spatial counter-elements (energy bonds and media and, basically, substance structures) form of local worlds within it through evolution of informational structures. The organic world of reproduction develops through the open informational path: the initial substance, through energy exchange and metabolism, reproduces similar substance; the latter interacts with the environment and, subsequently, (...) reproduces its like, and so on. The animal world of self-regulation builds up a closed informational contour in the environment through the informational input and command output. The human world of self-cognition forms the intensive type of development within the internal closed informational contour of cognition. Counter-transitions of ideal images and signs relate to their real prototypes. In the course of cognition, abstractive thinking develops and brings man to the possibility of reflection of the initial world in its integrity (thus, elevates man to the infinite, by Hegel). (shrink)

This book’s basic argument is that the Freudian unconscious, far from constituting a radical break with the philosophy of consciousness, is merely the latest exemplar in a heritage of philosophical misunderstanding of the Cartesian cogito that interprets “I think, therefore I am” as “I represent myself, therefore I am” (in the classic interpretation of Heidegger, one of the targets of the book).

Despite there being little consensus on what intelligence is or how to measure it, the media and the public have become increasingly preoccupied with the concept owing to recent accomplishments in machine learning and research on artificial intelligence (AI). Governments and corporations are investing billions of dollars to fund researchers who are keen to produce an ever‐expanding range of artificial intelligent systems. More than 30 countries have announced such research initiatives over the past 3 years 1. For example, the EU (...) Commission pledged to increase the investment in AI research to €1.5 billion by 2020 (from €500 million in 2017), while China has committed $2.1 billion towards an AI technology park in Beijing alone 1. This global investment in AI is astonishing and prompts several questions: What are the true possibilities and limitations of AI? What do AI researchers and developers mean by “intelligence”? How does this compare to the everyday concept of intelligence and how the term is other branches of cognitive science? And can machine learning produce anything that is truly “intelligent”? (shrink)

"La philosophie en terre d'Islam n'a ps seulement receuilli l'héritage des Grecs. Jusqu'à nos jours, elle n'a cessé d'engendrer une des plus riches métaphysiques qui soient. Henri Corbin nous dévoile comment des Ismaéliens à Avicenne, de Sohravardi ou Ibn' Arabi à l'Ecole d'Ispahan, s"est constituée une exégèse du Livre saint, et comment est née une philosophie prophétique.

[opening paragraph]: In his keynote paper David Chalmers defines ‘the hard problem’ by posing certain ‘Why’ questions about consciousness? Such questions must be posed within an appropriate setting. The way of science is to try to deduce the answer to many such questions from a few well defined assumptions. Much about nature can be explained in terms of the principles of classical mechanics. The assumptions, in this explanatory scheme, are that the world is composed exclusively of particles and fields governed (...) by specified mathematical laws that refer neither to any individual person, nor to anyone’s experiences. These physical laws are supposed to be such that particles and fields, acting in concert, can form causally efficacious real functional entities such as driveshafts and propellers. Similarly, surges of electrical and mechanical activity in appropriately designed material substrates, composed of particles and fields acting in concert, could implement, in the world of matter, complex functional structures and long sequences of logical operations. Thus it is conceivable that all of our behaviour, and all of the internal processing that occurs in our bodies and brains could be deduced, at least in principle, from the principles of classical mechanics and appropriate boundary conditions. -/- Contents: 1. Introduction: Philosophical Setting 2. Quantum Model of the Mind/Brain 3. Person and Self 4. Meeting Baars's Criteria for Consciousness 5. Qualia 6. Free-Will. (shrink)

In the context of theories of the connection between mind and brain, physicalism is the demand that all is basically purely physical. But the conception of “physical” embodied in this demand is characterized essentially by the properties of the physical that hold in classical physical theories. Certain of those properties contradict the character of the physical in quantum mechanics, which provides a better, more comprehensive, and more fundamental account of phenomena. It is argued that the difficulties that have plagued physicalists (...) for half a century, and that continue to do so, dissolve when the classical idea of the physical is replaced by its quantum successor. The argument is concretized in way that makes it accessible to non-physicists by exploiting the recent evidence connecting our conscious experiences to macroscopic measurable synchronous oscillations occurring in wellseparated parts of the brain. A specific new model of the mind-brain connection that is fundamentally quantum mechanical but that ties conscious experiences to these macroscopic synchronous oscillations is used to illustrate the essential disparities between the classical and quantum notions of the physical, and in particular to demonstrate the failure in the quantum world of the principle of the causal closure of the physical, a failure that goes beyond what is entailed by the randomness in the outcomes of observations, and that accommodates the efficacy in the brain of conscious intention. (shrink)