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  1. Transmission par-delà les gènes : propos sur le don de gamètes dans différents cas de paternité.Nicolas Mendes, François Pommier & Agnès Condat - 2018 - Dialogue 1:25-36.
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  2. Genes, Genesis and God: Values and Their Origins in Natural and Human History.John Hedley Brooke - 2000 - Environmental Values 9:401.
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  3. Deficits of Public Deliberation in U.S. Oversight for Gene Edited Organisms.Jennifer Kuzma - 2021 - Hastings Center Report 51 (S2):25-33.
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  4. Envisioning Complex Futures: Collective Narratives and Reasoning in Deliberations Over Gene Editing in the Wild.Ben Curran Wills, Michael K. Gusmano & Mark Schlesinger - 2021 - Hastings Center Report 51 (S2):92-100.
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  5. Public Deliberation About Gene Editing in the Wild.Michael K. Gusmano, Gregory E. Kaebnick, Karen J. Maschke, Carolyn P. Neuhaus & Ben Curran Wills - 2021 - Hastings Center Report 51 (S2):2-10.
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  6. Narratives in Public Deliberation: Empowering Gene Editing Debate with Storytelling.Kaiping Chen & Michael M. Burgess - 2021 - Hastings Center Report 51 (S2):85-91.
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  7. Empowering Indigenous Knowledge in Deliberations on Gene Editing in the Wild.Riley Taitingfong & Anika Ullah - 2021 - Hastings Center Report 51 (S2):74-84.
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  8. Giving Voice to the Voiceless in Environmental Gene Editing.Natalie Kofler & Colleen M. Grogan - 2021 - Hastings Center Report 51 (S2):66-73.
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  9. The Decision Phases Framework for Public Engagement: Engaging Stakeholders About Gene Editing in the Wild.S. Kathleen Barnhill-Dilling, Adam Kokotovich & Jason A. Delborne - 2021 - Hastings Center Report 51 (S2):48-61.
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  10. Deterministic Attributions of Behavior: Brain versus Genes.Kevin R. Peters, Alena Kalinina, Nastassja M. Downer & Amy Van Elswyk - 2021 - Neuroethics 14 (3):507-528.
    This research examined the influence of social-, genetic-, and brain-based explanations on attributions of others’ behaviors. Participants were university students in Studies 1, 2, and 3. Participants read a vignette about an individual who possessed several undesirable behaviors and answered related questions. The first two studies had within-subjects designs. Participants in Study 1 were provided with social-, genetic-, and brain-based explanations for the individual’s behavior. The order of the genetic- and brain-based explanations was reversed in Study 2. Study 3 used (...)
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  11. The Complexity of the Gene and the Precision of CRISPR : What is the Gene That is Being Edited?Esha Shah, David Ludwig & Phil Macnaghten - 2021 - Elementa: Science of Anthropocene 9.
    The rapid development of CRISPR-based gene editing has been accompanied by a polarized governance debate about the status of CRISPR-edited crops as genetically modified organisms. This article argues that the polarization around the governance of gene editing partly reflects a failure of public engagement with the current state of research in genomics and postgenomics. CRISPR-based gene-editing technology has become embedded in a narrow narrative about the ease and precision of the technique that presents the gene as a stable object under (...)
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  12. Bioscience in light of Dependent Arising and Emptiness: The Gene in Buddhism.Sun Kyeong Yu - 2021 - In Buddhism and Culture. Seoul, South Korea: pp. 42-28.
    “Non-Self from the perspective of the Gene” November 2021, Buddhism and Culture (a Korean-language Buddhist magazine sponsored by the Foundation for the Promotion of Korean Buddhism), Korea.
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  13. Modelling Gene Regulation: (De)Compositional and Template-Based Strategies.Tarja Knuuttila & Vivette García Deister - 2019 - Studies in History and Philosophy of Science Part A 77:101-111.
    Although the interdisciplinary nature of contemporary biological sciences has been addressed by philosophers, historians, and sociologists of science, the different ways in which engineering concepts and methods have been applied in biology have been somewhat neglected. We examine - using the mechanistic philosophy of science as an analytic springboard - the transfer of network methods from engineering to biology through the cases of two biology laboratories operating at the California Institute of Technology. The two laboratories study gene regulatory networks, but (...)
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  14. Primum Non Nocere: Should Gene Therapy Be Used to Prevent Potentially Fatal Disease but Enable Potentially Destructive Behavior?Inmaculada de Melo-Martin & Ronald G. Crystal - 2021 - Human Gene Therapy 32 (11-12):529-534.
    Aldehyde dehydrogenase 2 (ALDH2) deficiency constitutes one of the most common hereditary enzyme deficiencies, affecting 35% to 40% of East Asians and 8% of the world population. It causes the well-known Asian Alcohol Flush Syndrome, characterized by facial flushing, palpitation, tachycardia, nausea, and other unpleasant feelings when alcohol is consumed. It is also associated with a marked increase in the risk of a variety of serious disorders, including esophageal cancer and osteoporosis. Our recent studies with murine models have demonstrated that (...)
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  15. Gene Editing of Human Embryos is Not Contrary to Human Rights Law: A Reply to Drabiak.Andrea Boggio & Rumiana Yotova - forthcoming - Wiley: Bioethics.
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  16. Culture, Genes, Selection, and Learning: A Response to Nichols, Mackey & Moll.Anton Killin & Ross Pain - forthcoming - Philosophical Psychology.
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  17. From Darwin to Derrida: Selfish Genes, Social Selves, and the Meanings of Life.Stanley Shostak - forthcoming - The European Legacy:1-4.
    David Haig’s From Darwin to Derrida scrutinizes a wide range of historical and contemporary issues embedded in the theory and practice of genetics—from genes to multilevel selection, from prokaryot...
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  18. Fishing for Genes: How the Largest Gene Family in the Mammalian Genome Was Found.Ann-Sophie Barwich - 2021 - Perspectives on Science 29 (4):359-387.
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  19. Regulating Animals with Gene Drive Systems: Lessons From the Regulatory Assessment of a Genetically Engineered Mosquito.Zahra Meghani & Jennifer Kuzma - 2018 - Journal of Responsible Innovation 5 (S1).
    For the purposes of conservation or suppression of species, gene drive technology has significant potential. Theoretically speaking, with the release of even relatively few animals with gene drive systems in an ecosystem, beneficial or harmful genes could be introduced into the entire wild-type population of that species. Given the profound impact that gene drives could have on species and ecosystems, their use is a highly contentious issue. Communities and groups have differing beliefs about nature and its conservation or preservation, as (...)
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  20. The Interaction of Child Abuse and Rs1360780 of the FKBP5 Gene is Associated with Amygdala Resting-State Functional Connectivity in Young Adults.Christiane Wesarg, Ilya M. Veer, Nicole Y. L. Oei, Laura S. Daedelow, Tristram A. Lett, Tobias Banaschewski, Gareth J. Barker, Arun L. W. Bokde, Erin Burke Quinlan, Sylvane Desrivières, Herta Flor, Antoine Grigis, Hugh Garavan, Rüdiger Brühl, Jean-Luc Martinot, Eric Artiges, Frauke Nees, Dimitri Papadopoulos Orfanos, Luise Poustka, Sarah Hohmann, Juliane H. Fröhner, Michael N. Smolka, Robert Whelan, Gunter Schumann, Andreas Heinz & Henrik Walter - 2021 - Human Brain Mapping 42 (10).
    Extensive research has demonstrated that rs1360780, a common single nucleotide polymorphism within the FKBP5 gene, interacts with early-life stress in predicting psychopathology. Previous results suggest that carriers of the TT genotype of rs1360780 who were exposed to child abuse show differences in structure and functional activation of emotion-processing brain areas belonging to the salience network. Extending these findings on intermediate phenotypes of psychopathology, we examined if the interaction between rs1360780 and child abuse predicts resting-state functional connectivity between the amygdala and (...)
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  21. Was Sind Gene Nicht?: Über Die Grenzen des Biologischen Essentialismus.Kirsten Schmidt - 2013 - Transcript Verlag.
    Gene gelten im Allgemeinen als die Essenz eines Lebewesens, die all seine charakteristischen Eigenschaften bestimmt. Aus biologischer Sicht trifft diese Vorstellung jedoch längst nicht mehr zu. Im Mittelpunkt dieses Buches steht daher die Frage, warum und wie das essentialistische Denken die gesellschaftliche Wahrnehmung biologischer Forschungsprojekte immer noch beeinflusst. Anhand aktueller Erkenntnisse der Genetik und Epigenetik geht Kirsten Schmidt auf die Suche nach einer neuen Interpretation des Genbegriffs im Zeitalter der Postgenomik. Das Verständnis von Genen als dynamischen Prozessen erweist sich dabei (...)
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  22. Clinical Trials of Germline Gene Editing: The Exploitation Problem.Erik Malmqvist - 2021 - Bioethics 35 (7):688-695.
    Bioethics, Volume 35, Issue 7, Page 688-695, September 2021.
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  23. Developing Gamified Instructional Materials in Genetics for Grade 12 STEM.Aaron Funa & Jhonner Ricafort - 2019 - International Journal of Engineering Science and Computing 9 (3):20597-20600.
    As technology advances, the demand for innovative instructional materials also increases. As a result, the Department of Education urges teachers to develop instructional materials. This study was conducted at Bulusan National High School, Bulusan, Sorsogon, Philippines SY 2018-2019 which was aimed to develop gamified instructional materials in genetics that would aid in teaching and learning process of grade 12 STEM students. The developed gamified materials were collectively called the GIM in Genetics which is comprised of two parts; namely, Student’s Portfolio (...)
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  24. Validation of Gamified Instructional Materials in Genetics for Grade 12 STEM Students.Aaron Funa & Jhonner Ricafort - 2019 - International Journal of Sciences: Basic and Applied Research 47 (2):168-180.
    Instructional material is an integral part of teaching and learning process. Validating instructional materials is imperative to ensure quality before widespread utilization. This study validated the developed Gamified Instructional Material (GIM) in genetics for grade 12 STEM students. It employed the descriptive-developmental research design involving 41 STEM students and 11 Biology education experts chosen through purposive sampling. Findings revealed that students and experts strongly agreed that the GIM satisfied the criteria for a sound and valid instructional material. Further, the significant (...)
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  25. The Full Bayesian Significance Test for Mixture Models: Results in Gene Expression Clustering.Julio Michael Stern, Marcelo de Souza Lauretto & Carlos Alberto de Braganca Pereira - 2008 - Genetics and Molecular Research 7 (3):883-897.
    Gene clustering is a useful exploratory technique to group together genes with similar expression levels under distinct cell cycle phases or distinct conditions. It helps the biologist to identify potentially meaningful relationships between genes. In this study, we propose a clustering method based on multivariate normal mixture models, where the number of clusters is predicted via sequential hypothesis tests: at each step, the method considers a mixture model of m components (m = 2 in the first step) and tests if (...)
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  26. Gene Editing, Identity and Benefit.Thomas Douglas & Katrien Devolder - 2021 - Philosophical Quarterly 1:pqab029.
    Some suggest that gene editing human embryos to prevent genetic disorders will be in one respect morally preferable to using genetic selection for the same purpose: gene editing will benefit particular future persons, while genetic selection would merely replace them. We first construct the most plausible defence of this suggestion—the benefit argument—and defend it against a possible objection. We then advance another objection: the benefit argument succeeds only when restricted to cases in which the gene-edited child would have been brought (...)
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  27. 'Genes, Memes and Human History' by Stephen Shennan. [REVIEW]Kim Sterelny - 2004 - Mind and Language 19 (2):249-257.
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  28. Perspectives on Integrating Developmental and Evolutionary Biology: Genes in Development: Re-Reading the Molecular Paradigm, Eva M. Neumann-Held and Christoph Rehmann-Sutter , Eds. Durham, NC: Duke University Press, 2006, (384 Pp; $23.95 Pbk; ISBN 0-8223-3656-1).Jonathan Kaplan - 2007 - Biological Theory 2 (4):427-429.
  29. Book ReviewsJonathan Glover,. Choosing Children: Genes, Disability, and Design. Oxford: Oxford University Press, 2006. Pp. 121. $17.95. [REVIEW]Marc Workman - 2007 - Ethics 118 (1):155-160.
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  30. Holmes Rolston, III Genes, Genesis and God: Values and Their Origins in Natural and Human History. . Pp. Xvi+400. £40.00 . £14.95. [REVIEW]Mikael Stenmark - 2001 - Religious Studies 37 (2):223-246.
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  31. SarahS.Richardson, Sex Itself. The Search for Male and Female in the Human Genome: Chicago and London: University of Chicago Press, 2013, Vii + 311pp., Illus., $48.00.Howard Chiang - 2017 - History and Philosophy of the Life Sciences 39 (2).
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  32. The Evolving Landscape of Imprinted Genes in Humans and Mice: Conflict Among Alleles, Genes, Tissues, and Kin.Jon F. Wilkins, Francisco Úbeda & Jeremy Van Cleve - 2016 - Bioessays 38 (5):482-489.
    Three recent genome‐wide studies in mice and humans have produced the most definitive map to date of genomic imprinting (gene expression that depends on parental origin) by incorporating multiple tissue types and developmental stages. Here, we explore the results of these studies in light of the kinship theory of genomic imprinting, which predicts that imprinting evolves due to differential genetic relatedness between maternal and paternal relatives. The studies produce a list of imprinted genes with around 120–180 in mice and ∼100 (...)
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  33. The Electric Fence to Cell-Cycle Progression: Do Local Changes in Membrane Potential Facilitate Disassembly of the Primary Cilium?Diana Urrego, Araceli Sánchez, Adam P. Tomczak & Luis A. Pardo - 2017 - Bioessays 39 (6):1600190.
    Kv10.1 is a voltage‐gated potassium channel relevant for tumor biology, but the underlying mechanism is still unclear. We propose that Kv10.1 plays a role coordinating primary cilium disassembly with cell cycle progression through localized changes of membrane potential at the ciliary base. Most non‐dividing cells display a primary cilium, an antenna‐like structure important for cell physiology. The cilium is disassembled when the cell divides, which requires an increase of Ca2+ concentration and a redistribution of phospholipids in its basal region, both (...)
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  34. RNA Meets DNA: The Potential for Gene Expression to Produce Short RNA Molecules Capable of Generating DNA Mutation and Driving Genome Evolution.Robert S. Young - 2017 - Bioessays 39 (10):1700141.
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  35. The Promise and Peril of CRISPR Gene Drives.Gabriel E. Zentner & Michael J. Wade - 2017 - Bioessays 39 (10):1700109.
    Gene drives are selfish genetic elements that use a variety of mechanisms to ensure they are transmitted to subsequent generations at greater than expected frequencies. Synthetic gene drives based on the clustered regularly interspersed palindromic repeats genome editing system have been proposed as a way to alter the genetic characteristics of natural populations of organisms relevant to the goals of public health, conservation, and agriculture. Here, we review the principles and potential applications of CRISPR drives, as well as means proposed (...)
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  36. Dependence Relationships Between Gene Ontology Terms Based on TIGR Gene Product Annotations.Anand Kumar, Barry Smith & Christian Borgelt - 2004 - Proceedings of the 3rd International Workshop on Computational Terminology 2004:31-38.
    The Gene Ontology is an important tool for the representation and processing of information about gene products and functions. It provides controlled vocabularies for the designations of cellular components, molecular functions, and biological processes used in the annotation of genes and gene products. These constitute three separate ontologies, of cellular components), molecular functions and biological processes, respectively. The question we address here is: how are the terms in these three separate ontologies related to each other? We use statistical methods and (...)
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  37. Book Review : Prospects for a Common Morality, Edited by Gene Outka and John P. Reeder, Jr. Princeton, N.J., and London, Princeton University Press, 1992. 302 Pp. £32.50 , £12.95. [REVIEW]Guenther Haas - 1994 - Studies in Christian Ethics 7 (2):138-141.
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  38. Review of Who Owns You?: The Corporate Gold Rush to Patent Your Genes. [REVIEW]David Resnik - 2010 - Studies in Ethics, Law, and Technology 4 (1).
  39. Gene Ontology Annotations: What They Mean and Where They Come From.P. Hill David, Barry Smith, S. McAndrews-Hill Monica & A. Blake Judith - 2008 - BMC Bioinformatics 9 (Suppl 5):S2.
    The computational genomics community has come increasingly to rely on the methodology of creating annotations of scientific literature using terms from controlled structured vocabularies such as the Gene Ontology (GO). We here address the question of what such annotations signify and of how they are created by working biologists. Our goal is to promote a better understanding of how the results of experiments are captured in annotations in the hope that this will lead to better representations of biological reality through (...)
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  40. Countering Kauffman with Connectionism: Two Views of Gene Regulation and the Fundamental Nature of Ontogeny: Articles.Roger Sansom - 2008 - British Journal for the Philosophy of Science 59 (2):169-200.
    Understanding the operation and evolution of gene regulation networks is critical to understanding ontogeny and evolution. According to Stuart Kauffman's view, each cell type cycles through its own repeated pattern of gene expression, the order of ontogeny is dependent on these cycles being short, and evolution is possible because these cycles mutate gradually. This view of gene regulation reflects Kauffman's view that ontogeny is fundamentally the process of cells repeating cycles of activity. I criticize Kauffman's view of gene regulation networks (...)
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  41. Genetic Databases and Pharmacogenetics: Introduction.Richard E. Ashcroft & Adam M. Hedgecoe - 2004 - Studies in History and Philosophy of Biological and Biomedical Sciences 37 (3):499-502.
    Since the inception of the Human Genome Project, human genetics has frequently been conducted through big science projects, combining academic, state and industrial methods, interests and resources. The legitimacy of such projects has been linked to national prestige and images of the nation, the purity of scientific endeavour, the entrepreneurial spirit, medical progress and the public health. A key complication in these discourses is that large-scale genetic research has yet to show major results when considered in terms of the objectives (...)
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  42. Genes After the Human Genome Project.Tudor M. Baetu - 2012 - Studies in History and Philosophy of Biological and Biomedical Sciences 43 (1):191-201.
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  43. Introduction: The Lotus Sutra and Process Thought.Gene Reeves - 2001 - Journal of Chinese Philosophy 28 (4):355-356.
  44. The Extended Phenotype: The Gene as the Unit of Selection. Richard Dawkins.Robert C. Richardson - 1984 - Philosophy of Science 51 (2):357-359.
  45. Ethics and the Human Genome Project.H. Paske Gerald - unknown
    Full text of this article is not available in SOAR.
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  46. Two Consequences of Richard Dawkins' View of Genes and Organisms.M. Hampe - 1988 - Studies in History and Philosophy of Science Part A 19 (1):119.
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  47. What is a Gene?Raphael Falk - 1986 - Studies in History and Philosophy of Science Part A 17 (2):133.
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  48. Ethical Aspects of Human Germ‐Line Gene Therapy.Maurice A. M. de Wachter - 1993 - Bioethics 7 (2-3):166-177.
  49. Identity and the Ethics of Gene Therapy.Robert Elliot - 1993 - Bioethics 7 (1):27-40.
  50. Human Germline Gene Therapy: Scientific, Moral and Political Issues: David B Resnik, Holly B Steinkraus and Pamela J Langer, Austin, Texas, R G Landes Company, 1999, 189 Pages, US$99.00 (Hb). [REVIEW]Nils Holtug - 2001 - Journal of Medical Ethics 27 (1):67-68.
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