The theme of the third annual Spring workshop of the HUPO-PSI was proteomics and beyond and its underlying goal was to reach beyond the boundaries of the proteomics community to interact with groups working on the similar issues of developing interchange standards and minimal reporting requirements. Significant developments in many of the HUPO-PSI XML interchange formats, minimal reporting requirements and accompanying controlled vocabularies were reported, with many of these now feeding into the broader efforts of the Functional Genomics Experiment data (...) model and Functional Genomics Ontology ontologies. (shrink)

Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

Pathological morphogenesis on leaves of Fraxinus ornus (ash) and Solanum lycopersicum (tomato) under the influence of mites (Aceria fraxinivora and Eriophyes cladophthirus respectively) leads to a range of structures whose morphology and development cannot be reduced to the classical categories of plant morphology, but present a heterogeneous continuum which links fundamental structural categories. These findings support the pyramid model of plant construction.

Research seeking a scientific foundation for the theory of art appreciation has raised controversies at the intersection of the social and cognitive sciences. Though equally relevant to a scientific inquiry into art appreciation, psychological and historical approaches to art developed independently and lack a common core of theoretical principles. Historicists argue that psychological and brain sciences ignore the fact that artworks are artifacts produced and appreciated in the context of unique historical situations and artistic intentions. After revealing flaws in the (...) psychological approach, we introduce a psycho-historical framework for the science of art appreciation. This framework demonstrates that a science of art appreciation must investigate how appreciators process causal and historical information to classify and explain their psychological responses to art. Expanding on research about the cognition of artifacts, we identify three modes of appreciation: basic exposure to an artwork, the artistic design stance, and artistic understanding. The artistic design stance, a requisite for artistic understanding, is an attitude whereby appreciators develop their sensitivity to art-historical contexts by means of inquiries into the making, authorship, and functions of artworks. We defend and illustrate the psycho-historical framework with an analysis of existing studies on art appreciation in empirical aesthetics. Finally, we argue that the fluency theory of aesthetic pleasure can be amended to meet the requirements of the framework. We conclude that scientists can tackle fundamental questions about the nature and appreciation of art within the psycho-historical framework. (shrink)

In a world that has become increasingly dependent upon employee ownership, commitment, and initiative, organizations need leaders who can inspire their␣employees and motivate them individually. Love, forgiveness, and trust are critical values of today’s organization leaders who are committed to maximizing value for organizations while helping organization members to become their best. We explain the importance of love, forgiveness, and trust in the modern organization and identify 10 commonalities of these virtues.

Population counts and longitude and latitude coordinates were estimated for the 50 largest cities in the United States by computational linguistic techniques and by human participants. The mathematical technique Latent Semantic Analysis applied to newspaper texts produced similarity ratings between the 50 cities that allowed for a multidimensional scaling (MDS) of these cities. MDS coordinates correlated with the actual longitude and latitude of these cities, showing that cities that are located together share similar semantic contexts. This finding was replicated using (...) a first‐order co‐occurrence algorithm. The computational estimates of geographical location as well as population were akin to human estimates. These findings show that language encodes geographical information that language users in turn may use in their understanding of language and the world. (shrink)

Combining testimonial reports from independent and partially reliable information sources is an important epistemological problem of uncertain reasoning. Within the framework of Dempster–Shafer theory, we propose a general model of partially reliable sources, which includes several previously known results as special cases. The paper reproduces these results on the basis of a comprehensive model taxonomy. This gives a number of new insights and thereby contributes to a better understanding of this important application of reasoning with uncertain and incomplete information.

Although the genetics of dorsal‐ventral polarity which leads to mesoderm formation in Drosophila are understood in considerable detail, subsequent molecular mechanisms involved in patterning the mesoderm primordium into individual mesodermal subtypes are poorly understood. Two papers published recently (1,2) suggest strongly that an inductive signal from dorsal ectoderm is involved in subdividing the underlying mesoderm, and present evidence that one of the signalling factors is Decapentaplegic (Dpp), a member of the bone morphogenetic protein subgroup of the Transforming Growth Factor‐β (TGF‐β) (...) super family of proteins. (shrink)

In der 1970 gegründeten Reihe erscheinen Arbeiten, die philosophiehistorische Studien mit einem systematischen Ansatz oder systematische Studien mit philosophiehistorischen Rekonstruktionen verbinden. Neben deutschsprachigen werden auch englischsprachige Monographien veröffentlicht. Gründungsherausgeber sind: Erhard Scheibe (Herausgeber bis 1991), Günther Patzig (bis 1999) und Wolfgang Wieland (bis 2003). Von 1990 bis 2007 wurde die Reihe von Jürgen Mittelstraß mitherausgegeben.

Schule und Hochschule sind als als dispositive Ordnung in diversen Texten thematisiert worden, etwa bei Michel Foucault und Michel Serres zum Spannungsfeld von Unterwerfung und Selbstbestimmung. Die performative Beschreibung der Schulsituation durch Elise v. Bernstorff ermöglicht dabei eine neue Perspektive auf das Dispositiv von Klang und Zeit, der hier nachgegangen wird.

Originally presented as the author's thesis (doctoral)--Universit'at Erlangen-N'urnberg, 1981.

Gibt es einen spezifisch "linken" Kitsch in Abgrenzung zu politisch "rechtem"? Dieser vernachlässigten, für das Verständnis "linken Denkens" seit der Französischen Revolution aber wichtigen Frage gehen die Beiträge dieses Bandes nach.0Gezeigt wird, dass "linkes" Denken aus ganz anderen Gründen kitschanfällig ist als sein "rechtes" Pendant, auch wenn die Pathosformeln sich mitunter frappierend ähneln. Denn während rechte Ideologien den Veränderungsdruck der Moderne kompensieren, streben linke eher danach, ihn nach dem Motto "Mehr desselben" zu überbieten. Dieses Phänomen »linker Kitsch± nimmt der Band (...) in historischer und theoretischer Hinsicht anhand von sprachlichen, bildlichen und filmischen Beispielen in den Blick, sodass es in seinem konstitutiv transmedialen Charakter zur Geltung kommt. (shrink)

Previous reports have demonstrated that the comprehension of sentences describing motion in a particular direction (toward, away, up, or down) is affected by concurrently viewing a stimulus that depicts motion in the same or opposite direction. We report 3 experiments that extend our understanding of the relation between perception and language processing in 2 ways. First, whereas most previous studies of the relation between perception and language processing have focused on visual perception, our data show that sentence processing can be (...) affected by the concurrent processing of auditory stimuli. Second, it is shown that the relation between the processing of auditory stimuli and the processing of sentences depends on whether the sentences are presented in the auditory or visual modality. (shrink)

Zeki and co-workers recently proposed that perception can best be described as locally distributed, asynchronous processes that each create a kind of microconsciousness, which condense into an experienced percept. The present article is aimed at extending this theory to metacognitive feelings. We present evidence that perceptual fluency—the subjective feeling of ease during perceptual processing—is based on speed of processing at different stages of the perceptual process. Specifically, detection of briefly presented stimuli was influenced by figure-ground contrast, but not by symmetry (...) or the font of the stimuli. Conversely, discrimination of these stimuli was influenced by whether they were symmetric and by the font they were presented in , but not by figure-ground contrast. Both tasks however were related with the subjective experience of fluency . We conclude that subjective fluency is the conscious phenomenal correlate of different processing stages in visual perception. (shrink)

Der Band enthält die drei bislang unveröffentlichten "Krisenhefte" von Marx mit Exzerpten, Zeitungsausschnitten und Notizen, die 1857/1858 während der ersten Weltwirtschaftskrise entstanden sind. Die Materialsammlung dokumentiert Marx’ empirische Untersuchung dieser Krise, die er mit der Zusammenstellung und Systematisierung von Artikeln, Angaben und Kommentaren aus führenden Zeitungen wie "The Times", "The Morning Star", "The Standard", "The Manchester Guardian" und "The Economist" durchführte. In den Auszügen werden Wirtschafts- und Finanzfragen in den europäischen Ländern sowie den USA, China, Indien, Ägypten, Australien und Brasilien (...) behandelt, der Finanz- und Warenmarkt untersucht, sowie Daten zu Konkursen, Arbeitslosigkeit, Kurzarbeit, Lohnentwicklung und Arbeitskämpfen festgehalten. Die Krisenhefte stehen in engem Zusammenhang mit Marx’ "Grundrissen der Kritik der politischen Ökonomie", seinen Artikeln für die "New-York Tribune" und Debatten mit Engels, in denen allesamt die Krise 1857/58 analysiert wird. (shrink)

The experiactional stream of a person can be seen to be organized. It takes place in situation as a "situated event." Events have a duration through time; they could be called: Time-Gestalten. Events first tend to appear in the stream of experience in imaginary anticipation usually as a result of a social invitation or as a self-initiated project. In anticipatory experience projected events are developed, worked-on, thought about on repeated occasions. The event takes shape in experience as an anticipation before (...) it takes place . This has consequences and is important because strategy-decisions are made which actually create the future event. During the recorded experience I actually decided what I was going to do for the lecture. The meaning of this anticipated event which has personal as well as social-professional horizons sets limits to what is allowed into the imaginary anticipation or the projecting. They could be said to act as "charges" upon my experiaction here and now. It seems that the event in anticipatory elaboration is richer and allows more play in experience. As we approach the actualization proper the range of possibilities narrows. Anticipation has to become embodied: it springs into action and enters the domain of public and shared social reality. We witness the event. Any component of the experiactional stream-particularly in the anticipating phases of event-structures-is built up in complex ways. This may be described as "interwovenness." Whatever we focus on can be seen to arise on a string of previous encounters reaching back into one's at bottom indeterminate biographical stock of experiaction. This stock hovers horizonally around the theme-what I pay attention to at the moment-and codetermines its meaning. This makes for idiosyncratic meanings. But our past experience is also in a good measure shared because it is based on experiences of communication to which I had access through language or images. To some extent, therefore, there is also a public and shared meaning to a perceived theme. Components of the experiactional stream are also gathered up and connected through a higher and unifying intention, the project. We take many steps to actualize a project, and we also seem to have more than one project going on at any one time. This tends to "mix-up" our stream of experiaction in surprising and complex ways. In this study I have taken a small step which turned out to be connected to the larger sequence of being involved in giving a lecture. This event as an over-arching project casts its shadow ahead of itself and colored my anticipatory experience in clearly definable ways. The general structural features uncovered here through reflection were present and at work during my experiaction although I was not explicitly aware of them at the time, while living them out. Nevertheless, my pre-reflective experiaction turned out to have been structured and organized. In what I thought was an unique-private experience there were revealed and operative general-universal structures. The personal-existential and the general-phenomenological components are inextricably intertwined and collaborative in the creation of human experience in a particular situation. They constitute a tension inherent in the flow of experiaction. In living we constantly move between these levels and as researchers in this field we always try to bridge this "gap" that arises in understanding which dichotomizes "lived immediacy" and "theoretical understanding." Either extreme-"just living" or "just thinking"-if emphasized unduly is an aberration. The human way is to experiact and to make sense of it so that mere living-out is humanized into living-with-awareness. This can never be fully accomplished but is always in process, ongoing. Everyone has to unfold his own awareness and understanding, recognizing that the depth or ground of living eludes objectification and final conceptual grasp. We can only tune-in. (shrink)