Recently, Gitik, Kanovei and the first author proved that for a classical Prikry forcing extension the family of the intermediate models can be parametrized by $\mathscr{P}(\omega)/\mathrm{finite}$. By modifying the standard Prikry tree forcing we define a Prikry-type forcing which also singularizes a measurable cardinal but which is minimal, i.e., there are \emph{no} intermediate models properly between the ground model and the generic extension. The proof relies on combining the rigidity of the tree structure with indiscernibility arguments resulting from the normality (...) of the associated measures. (shrink)

We show that many large cardinal notions up to measurability can be characterized through the existence of certain filters for small models of set theory. This correspondence will allow us to obtain a canonical way in which to assign ideals to many large cardinal notions. This assignment coincides with classical large cardinal ideals whenever such ideals had been defined before. Moreover, in many important cases, relations between these ideals reflect the ordering of the corresponding large cardinal properties both under direct (...) implication and consistency strength. (shrink)

The 1992 incorporation of an article by referendum in the SwissConstitution mandating that the federal government issue regulations onthe use of genetic material that take into account the dignity ofnonhuman organism raises philosophical questions about how we shouldunderstand what is meant by ``the dignity of nonhuman animals,'' andabout what sort of moral demands arise from recognizing this dignitywith respect to their genetic engineering. The first step in determiningwhat is meant is to clarify the difference between dignity when appliedto humans and (...) when applied to nonhumans. Several conceptions of humandignity should be rejected in favor of a fourth conception: the rightnot to be degraded. This right implies that those who have it have thecognitive capacities that are prerequisite for self-respect. In the caseof nonhuman organisms that lack this capacity, respecting their dignityrequires the recognition that their inherent value, which is tied totheir abilities to pursue their own good, be respected. This value isnot absolute, as it is in the case of humans, so it does not prohibitbreeding manipulations that make organisms more useful to humans. But itdoes restrict morally how sentient animals can be used. In regard togenetic engineering, this conception requires that animals be allowedthe uninhibited development of species specific functions, a positionshared by Holland and Attfield, as opposed to the Original Purposeconception proposed by Fox and the Integrity of the Genetic Make-upposition proposed by Rolston. The inherent value conception of dignity,as here defended, is what is meant in the Swiss Constitution article. (shrink)

The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO) project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to (...) existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI) and Phenotype Attribute and Trait Ontology (PATO) without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology) and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT)). The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource providing details on the people, policies, and issues being addressed in association with OBI. (shrink)

Biblical theology is confronted with tensions between love and justice. There are sometimes attempts to avoid these tensions by dissolving one side of the opposing concept. One such attempt is to identify love and mercy as the essence of Christian theology, overcoming law and reciprocal justice. However, such a dissolution is irresponsible not only ethically, but also theologically--as the discussion in a number of the studies collected in the present volume will demonstrate.

Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

We investigate a variety of cut and choose games, their relationship with (generic) large cardinals, and show that they can be used to characterize a number of properties of ideals and of partial orders: certain notions of distributivity, strategic closure, and precipitousness.

We estimate that 208,000 deep brain stimulation (DBS) devices have been implanted to address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters pooled data and determined that DBS expanded in its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. The DBS Think Tank was founded in 2012 providing a space where clinicians, engineers, researchers from industry and academia discuss current and emerging DBS technologies and logistical and ethical issues facing the field. (...) The emphasis is on cutting edge research and collaboration aimed to advance the DBS field. The Eighth Annual DBS Think Tank was held virtually on September 1 and 2, 2020 (Zoom Video Communications) due to restrictions related to the COVID-19 pandemic. The meeting focused on advances in: (1) optogenetics as a tool for comprehending neurobiology of diseases and on optogenetically-inspired DBS, (2) cutting edge of emerging DBS technologies, (3) ethical issues affecting DBS research and access to care, (4) neuromodulatory approaches for depression, (5) advancing novel hardware, software and imaging methodologies, (6) use of neurophysiological signals in adaptive neurostimulation, and (7) use of more advanced technologies to improve DBS clinical outcomes. There were 178 attendees who participated in a DBS Think Tank survey, which revealed the expansion of DBS into several indications such as obesity, post-traumatic stress disorder, addiction and Alzheimer’s disease. This proceedings summarizes the advances discussed at the Eighth Annual DBS Think Tank. (shrink)

A survey on the knowledge and attitudes towards the Austrian organ donation legislation (an opt-out solution) of selected groups of the Austrian population taking into account factors such as age, gender, level of education, affiliation to healthcare professions and health related studies was conducted.

Muße ist ein freies Verweilen in der Zeit jenseits von Zweckrationalismus. Die Eigenzeitlichkeit wird zum Freiraum simultaner Möglichkeiten unserer Lebensgestaltung. Muße zielt auf ästhetisch und räumlich inszenierte Lebensformen, die in der Zeit nicht der Herrschaft der Zeit unterliegen. Konzepte von Muße sind stets eingebettet in ihre historischen und kulturellen Kontexte. Der Band beleuchtet historische Paradigmen der Muße in ihren literarischen Inszenierungen, diskursiven Verflechtungen und performativen Effekten. Die Beiträge aus der Philosophie, Klassischen Philologie, Alten Kirchengeschichte, germanistischen Mediävistik, neueren deutschen Literatur, Anglistik, (...) Soziologie, Geschichtswissenschaft, Archäologie, Kunstgeschichte, Ethnologie und Sinologie untersuchen Muße als anthropologisches und kulturgeschichtlich distinktes Phänomen, das sich Zeitzwängen widersetzt und Freiräume eröffnet. Analysiert werden unterschiedliche Semantisierungen, Ähnlichkeiten und Umbesetzungen, wie beispielsweise 'Freizeit', die Überschneidungen, aber auch gravierende Abgrenzungen zur Muße aufweisen. (shrink)

The focus on translational research in clinical trials has the potential to generate clinically relevant genetic data that could have importance to patients. This raises challenging questions about communicating relevant genetic research results to individual patients. An exploratory pharmacogenetic analysis was conducted in the international ovarian cancer phase III trial, AGO-OVAR 16, which found that patients with clinically important germ-line BRCA1/2 mutations had improved progression-free survival prognosis. Mechanisms to communicate BRCA results were evaluated, because these findings may be beneficial to (...) patients and their families. Communicating individual BRCA results was not anticipated during clinical trial design. Consequently, options were not available for patients to indicate their preference for receiving their individual results when they signed pharmacogenetic informed consent. Differences in local requirements, clinical practice, and opinion regarding the ethical aspects of how to convey genetic results to patients are all potential barriers to returning individual BRCA results to patients. Communicating the aggregate BRCA result from this study provided clinical investigators with a mechanism to disseminate the overall study finding to patients while taking individual circumstances, local guidelines and clinical practice into account. This study illustrates the importance of increasing the clarity and scope of informed consent and the need for patient engagement to ensure clinical trial participants can indicate their preference regarding receipt of potentially important individual pharmacogenetic results. This study was registered in the NCT Clinical Trial Registry under NCT00866697 on March 19, 2009, following approval from participating ethics committees. (shrink)

Over recent years, the research community has been increasingly using preprint servers to share manuscripts that are not yet peer-reviewed. Even if it enables quick dissemination of research findings, this practice raises several challenges in publication ethics and integrity. In particular, preprints have become an important source of information for stakeholders interested in COVID19 research developments, including traditional media, social media, and policy makers. Despite caveats about their nature, many users can still confuse pre-prints with peer-reviewed manuscripts. If unconfirmed but (...) already widely shared first-draft results later prove wrong or misinterpreted, it can be very difficult to “unlearn” what we thought was true. Complexity further increases if unconfirmed findings have been used to inform guidelines. To help achieve a balance between early access to research findings and its negative consequences, we formulated five recommendations: (a) consensus should be sought on a term clearer than ‘pre-print’, such as ‘Unrefereed manuscript’, “Manuscript awaiting peer review” or ‘’Non-reviewed manuscript”; (b) Caveats about unrefereed manuscripts should be prominent on their first page, and each page should include a red watermark stating ‘Caution—Not Peer Reviewed’; (c) pre-print authors should certify that their manuscript will be submitted to a peer-review journal, and should regularly update the manuscript status; (d) high level consultations should be convened, to formulate clear principles and policies for the publication and dissemination of non-peer reviewed research results; (e) in the longer term, an international initiative to certify servers that comply with good practices could be envisaged. (shrink)

The class forcing theorem, which asserts that every class forcing notion ${\mathbb {P}}$ admits a forcing relation $\Vdash _{\mathbb {P}}$, that is, a relation satisfying the forcing relation recursion—it follows that statements true in the corresponding forcing extensions are forced and forced statements are true—is equivalent over Gödel–Bernays set theory $\text {GBC}$ to the principle of elementary transfinite recursion $\text {ETR}_{\text {Ord}}$ for class recursions of length $\text {Ord}$. It is also equivalent to the existence of truth predicates for the (...) infinitary languages $\mathcal {L}_{\text {Ord},\omega }$, allowing any class parameter A; to the existence of truth predicates for the language $\mathcal {L}_{\text {Ord},\text {Ord}}$ ; to the existence of $\text {Ord}$ -iterated truth predicates for first-order set theory $\mathcal {L}_{\omega,\omega }$ ; to the assertion that every separative class partial order ${\mathbb {P}}$ has a set-complete class Boolean completion; to a class-join separation principle; and to the principle of determinacy for clopen class games of rank at most $\text {Ord}+1$. Unlike set forcing, if every class forcing notion ${\mathbb {P}}$ has a forcing relation merely for atomic formulas, then every such ${\mathbb {P}}$ has a uniform forcing relation applicable simultaneously to all formulas. Our results situate the class forcing theorem in the rich hierarchy of theories between $\text {GBC}$ and Kelley–Morse set theory $\text {KM}$. (shrink)

Intensity profiles of emotional experience over time have been found to differ primarily in explosiveness and accumulation. However, the determinants of these temporal features remain poorly understood. In two studies, we examined whether emotion regulation strategies are predictive of the degree of explosiveness and accumulation of negative emotional episodes. Participants were asked to draw profiles reflecting changes in the intensity of emotions elicited either by negative social feedback in the lab or by negative events in daily life. In addition, trait, (...) and state usage of a set of emotion regulation strategies was assessed. Multilevel analyses revealed that trait rumination was positively associated with emotion accumulation. State rumination was also positively associated with emotion accumulation and, to a lesser extent, with emotion explosiveness. These results provide support for emotion regulation theories, which hypothesise that rumination is a central mechanism underlying the maintenance of negative emotions. (shrink)

The SARS-CoV-2 pandemic has highlighted the interdependency of healthcare systems and research organizations on manufacturers and suppliers of personnel protective equipment and the need for well-trained personnel who can react quickly to changing working conditions. Reports on challenges faced by research laboratory workers are rare in contrast to the lived experience of hospital health care workers. We report on experiences gained by RLWs who significantly contributed to combating the pandemic under particularly challenging conditions due to increased workload, sickness and interrupted (...) PPE supply chains. RLWs perform a broad spectrum of work with SARS-CoV-2 such as autopsies, establishment of virus cultures and infection models, development and verification of diagnostics, performance of virus inactivation assays to investigate various antiviral agents including vaccines and evaluation of decontamination technologies in high containment biological laboratories. Performance of autopsies and laboratory work increased substantially during the pandemic and thus led to highly demanding working conditions with working shifts of more than eight hours working in PPE that stressed individual limits and also the ergonomic and safety limits of PPE. We provide detailed insights into the challenges of the stressful daily laboratory routine since the pandemic began, lessons learned, and suggest solutions for better safety based on a case study of a newly established HCBL designed for autopsies and research laboratory work. Reduced personal risk, increased resilience, and stress resistance can be achieved by improved PPE components, better training, redundant safety measures, inculcating a culture of safety, and excellent teamwork. (shrink)

This chapter depicts the life and works of medieval Christian thinker Peter Lombard. Historically speaking, almost nothing is known of his family and early years. The letter from St. Bernard to Gilduin, abbot of St. Victor, during the first months of 1136 contained the first mention of Peter Lombard in a historical document. This chapter recounts his reputation as a teacher of theology and his decisive role in his selection as the bishop of Paris in 1159. Peter (...) Lombard's rising fame is attested not only to his titles; he was frequently considered as an expert in theological matters. He had distinctly drawn a fine line between respect for the tradition and the courage to innovate. There are some contemporary reports of Peter Lombard's lectures that give a glimpse of his style of teaching—his written doctrines did not always constitute his last word on a given topic. (shrink)

The chapter begins with a discussion on the place of medieval Christian thinker Peter Lombard in the intellectual history of Christianity. Lombard was born between 1095 and 1100 in the region of Novara in Lombardy and died in 1160 as a bishop of Paris. He was the author of a celebrated work entitled the Book of Sentences. This work severed for many centuries as the standard theological textbook in the Christian West. It was later replaced in the 16th century (...) by Thomas Aquinasɧs Summa theologiae. The chapter also highlights Lombard's organization of the theological material, his method of presentation, and the way in which he shaped doctrine in several major areas. (shrink)

Peter Lombard is best known as the author of a celebrated work entitled Book of Sentences, which for several centuries served as the standard theological textbook in the Christian West. It was the subject of more commentaries than any other work of Christian literature besides the Bible itself. The Book of Sentences is essentially a compilation of older sources, from the Scriptures and Augustine down to several of the Lombard's contemporaries, such as Hugh of Saint Victor and Peter (...) Abelard. Its importance lies in the Lombard's organisation of the theological material, his method of presentation, and the way in which he shaped doctrine in several major areas. Despite his importance, however, there is no accessible introduction to Peter Lombard's life and thought available in any modern language. This volume fills this considerable gap. Philipp W. Rosemann begins by demonstrating how the Book of Sentences grew out of a long tradition of Christian reflection-a tradition, ultimately rooted in Scripture, which by the twelfth century had become ready to transform itself into a theological system. Turning to the Sentences, Rosemann then offers a brief exposition of the Lombard's life and work. He proceeds to a book-by-book examination and interpretation of its main topics, including the nature and attributes of God, the Trinity, creation, angelology, human nature and the Fall, original sin, Christology, ethics, and the sacraments. He concludes by exploring how the Sentences helped shape the further development of the Christian tradition, from the twelfth century through the time of Martin Luther. (shrink)

This book provides papers of the conference of leading scientists and philosophers on the notion of progress of knowledge, which is constitutive of our modern selfunderstanding, from the perspective of their disciplines. Summary of contents: 1. GEorg Henrik von Wright, Progress: Fiction and Fact 2. WAlter Burkert, Impact and Limits of the Idea of Progress in Antiquity 3. AListair Crombie, Philosophical Commitments and Scientific Progress 4. SHigeru Nakayama, Chinese "Cyclic" View of History vs Japanese "Progress" 5. JEan Blondel, Political Progress: (...) Illusion or Reality 6. NIcholas Rescher, Progress and the Future 7. RUdolf Flotzinger, Progress and Development in Musical History 8. DAg Pravitz, Progress in Philosophy 9. JOhn D. BArrow, Time in the Universe 10. ANtonio Garcia-Bellido, Progress in Biological Evolution 11. GEreon Wolters, The Idea of Progress in Evolutionary Biology: Philosophical Considerations 12. PHilippe Lazar, The Idea of Progress in Human Health. (shrink)

This concluding chapter provides an overview on the work of great theologians who commented upon the Book of Sentences. Indeed, it elaborates upon Peter Lombard's heritage by attempting to present a broad sketch of the history of the Sentences commentaries in the Middle Ages and beyond. There is no denying that there are loose ends, gaps, and even inconsistencies in Peter Lombard's account of the Christian faith. Most patently perhaps, Peter fails to develop a coherent theory of (...) the central mystery of Christianity—the Incarnation. It highlights some of the most notable inconsistencies in connection with its understanding of grace. Indeed, some of the inconsistencies of the Book of Sentences may hold out the chance for us to rethink our own answers to some of the great questions of life. The little research that exists on the Sentences literature of the 15th century indicates a fascinating reversal of this trend. (shrink)

Religious texts seem to share a significant characteristic. They possess a narrative structure, as opposed to presenting a rational argument. This chapter analyzes how traditions develop around texts that have acquired such authoritative status as to become foundational. The New Testament, while fundamentally narrative in structure, encourages theological reflection, and that means, in other words, the penetration of the faith by means of reason. The chapter gives an overview of the theological debates and reflections of Latin Fathers, Church Fathers, and (...) other religious thinkers in Christian history. The century in which Peter Lombard was born and wrote his theology has become a subject largely taught by masters in their own schools. It has been reasoned that Peter Lombard created a system that would render the faith as intelligible as humanly possible through comprehensive coverage of all its major themes in a methodical order and the application of dialectical procedures to several layers of authoritative texts. (shrink)

It is estimated that there are between 600 and 900 extant manuscripts of the Book of Sentences today, an incredible number for a medieval piece of writing. Peter Lombard, after becoming dissatisfied with the limitations of the literary genre of the gloss imposed upon theological reflections, turned in the 1150s to the composition of a sentence collection in his celebrated work entitled the Book of Sentences. It was a form of writing that he knew from his contemporaries, such as (...) Master Otto who wrote Summa sententiarum. It was not a static work and underwent a process of revision. This chapter examines the structure of a typical chapter in the Book of Sentences, which characterized this great work, and this also highlights some of the strategies of argumentation that Peter Lombard employs in it. (shrink)

To the modern reader, it might seem surprising that the Book of Sentences finds allusions to the Trinity in the Old Testament. Book 1 of the Sentence opens with the use/enjoyment distinction, with which we have already acquainted ourselves. There follows a section comprising several chapters in which Lombard examines the evidence for the existence of three persons in the one Godhead. This chapter also tries to reflect upon Peter Lombard's ambiguous attitude toward the theological debates of his time, (...) or at least toward certain aspects of these debates—he was taking up a question reluctantly, not because of its inherent value but only in order not to pass over a point which featured prominently in contemporary debates. It concludes that Lombard was well aware of the kind of counterarguments that his teaching on charity was likely to provoke; indeed, a lively controversy about it seemed to have started during his own lifetime. (shrink)

This chapter examines Book II of Peter Lombard's Book of Sentences. In Book II, Peter Lombard presented his ideas with his usual sense of humility, recognizing the limits of the human mind in coming to grasp why man was created as an incarnate spirit, how precisely the details of angelic nature are to be understood, or why God allowed the devil to tempt humanity, knowing as He did that we would fall. This chapter also looks at the divine (...) nature and the inner-Trinitarian mysteries and God's effects in creation. This chapter provides a complete structure of Book II. Distinction 1 opens the book with reflections on the concept of creation and its reasons. Distinctions 2 through 11 are devoted to the first elements of creation: the angels. Distinctions 12 to 15 offer a hexaemeron. Distinctions 16 to 18 focus more specifically on the creation of mankind, Distinction 18 being devoted exclusively to the creation of woman. (shrink)

This chapter examines Book III of the Peter Lombard's Book of Sentences. The purpose of this chapter is not a historical study of the controversies that surrounded the Book of Sentences before it became the standard textbook of theology in the Christian West, but to examine the strange doctrine that seemed to have marred the Christology of the Sentences. It explains how several contemporary authors have followed Baltzer in his judgment concerning the flawed structure of Book III of the (...) Sentences. It is especially the inclusion of the virtues in Christology that has met with the disapproval of historians of theology. Pope Alexander III condemned Peter's Christology by calling it vicious doctrine. Despite the condemnation, Lombard's Christology did not detract from the esteem in which the Lombard's theology was held. (shrink)

This chapter takes the conception of the sacraments as a sign of Lombard's theological system. Since the sacraments owe their salvific force directly to Christ's exemplary virtue and charity, Christology and the theology of the sacraments are considered closely related to each other. In Book IV, Peter reminds us of the structure of his work: “Having treated of those matters which pertain to the doctrine of things that are to be enjoyed [i.e., the Trinity], that are to be used (...) [creation in general], and that are to be used and enjoyed [man, the angels, the virtues, and even Christ].” The conception of sacraments as signs appropriately places them in the final part of the Lombard's theological system, governed as that is by the Augustinian distinction between things and signs. (shrink)

In the Christian tradition, there have always been those eager to paint the last judgment and the events leading up to it in sensational and lurid colors. Peter Lombard's simple strategy in providing a reliable account of Last Things is to stay close to the scriptural evidence. The structure of the treatise of the Sentences on Last Things is also given. Distinctions 43 and 44 address the resurrection of the dead, Distinction 44 being devoted, in particular, to the condition (...) of the bodies of the resurrected. Distinction 45 asks what prayers, alms, and burial ceremonies can accomplish on behalf of the deceased. This chapter looks at Peter's reference to the blessed and the damned, whose respective fates in the hereafter have formed the subject matter of Book IV of the Sentences. (shrink)

Philippe Stern, qui fut conservateur en chef du Musée Guimet à Paris, est surtout connu comme historien des arts de l'Inde et de l'Asie du Sud-Est. Il a sinon créé, du moins perfectionné la méthode qui consiste à suivre l'évolution, à travers la vie d'un art, de motifs spécialement choisis pour en découvrir la chronologie jusque-là inconnue. Il a fait de cette méthode un outil sûr qui a permis en particulier de redresser la chronologie erronée de l'art khmer, d'établir la (...) chronologie de l'art cham de l'Annam ancien, de préciser la chronologie des temples hypogées de l'Inde classique et celles des nombreuses fondations du dernier grand roi khmer, Jayavarman VII. Mais cet archéologue, cet historien, ce conservateur de Musée fut surtout un amant du beau, préoccupé par la nature et le rôle profond de l'expérience esthétique. Ainsi mûrit lentement à travers toute une existence une oeuvre dont Beauté-Clef (Peter Lang, 1989) est un premier volet et dont voici le second volet. (shrink)

This paper evaluates the claim that it is possible to use nature’s variation in conjunction with retention and selection on the one hand, and the absence of ultimate groundedness of hypotheses generated by the human mind as it knows on the other hand, to discard the ascription of ultimate certainty to the rationality of human conjectures in the cognitive realm. This leads to an evaluation of the further assumption that successful hypotheses with specific applications, in other words heuristics, seem to (...) have a firm footing because they were useful in another context. I argue that usefulness evaluated through adaptation misconstrues the search for truth, and that it is possible to generate talk of randomness by neglecting aspects of a system’s insertion into a larger situation. The framing of the problem in terms of the elimination of unfit hypotheses is found to be unsatisfying. It is suggested that theories exist in a dimension where they can be kept alive rather than dying as phenotypes do. The proposal that the subconscious could suggest random variations is found to be a category mistake. A final appeal to phenomenology shows that this proposal is orphan in the history of epistemology, not in virtue of its being a remarkable find, but rather because it is ill-conceived. (shrink)

After the publication of Marcia Colish’s Peter Lombard in 1994, studies on the author of the Book of Sentences have entered a new phase. This article provides an assessment of the state of research in the field and makes suggestions for its further development. In an appreciation and critique of Marcia Colish’s contribution, it argues that Colish’s interpretation, for all its merit, errs on a number of points: the proofs of God’s existence, charity, and the structure of theological ethics (...) are important examples. The second part of the essay considers the potential of research on the tradition of commentaries upon the Sentences. Given the central place that this genre of theological writing occupied in Christian thought between the twelfth and the sixteenth centuries, the Sentences commentaries could serve as a window upon the tradition. It is suggested that study of the literary form of the commentaries will shed much light on changes in the conception of theology which occurred in the period under consideration. (shrink)

Die Moralphilosophie des 20. und 21. Jahrhunderts hat mit Konsequentialismus, Deontologie, Kontraktualismus und Tugendethik nicht nur höchst einflussreiche Theorieparadigmen produktiv weiterentwickelt, sondern auch eine Reihe wichtiger neuer Probleme aufgeworfen. Der vorliegende Band versammelt zentrale Beiträge der analytischen Moralphilosophie, u. a. von David Gauthier, Shelly Kagan, Frances Kamm, Thomas Nagel, Michael Slote, Christine Swanton und Susan Wolf, die für ein Verständnis gegenwärtiger Diskussionen in der normativen Ethik unabdingbar sind. -/- Inhaltsverzeichnis: Vorwort Einleitung: Analytische Moralphilosophie der Gegenwart -/- 1. Konsequentialismus Shelly Kagan: (...) Ein Plädoyer gegen die Alltagsmoral Peter Railton: Entfremdung, Konsequentialismus und die Anforderungen der Moral -/- 2. Deontologie Thomas Nagel: Ethik William David Ross: Was macht richtige Handlungen richtig? -/- 3. Kontraktualismus David Gauthier: Warum Kontraktualismus? Thomas Scanlon: Die Struktur des Kontraktualismus -/- 4. Tugendethik Christine Swanton: Eine tugendethische Theorie des richtigen Handelns Michael Slote: Akteursbasierte Tugendethik -/- 5. Moralische Aggregation John Taurek: Zählt die Anzahl? Frances M. Kamm: Aggregation und zwei moralphilosophische Methoden -/- 6. Das Prinzip der Doppelwirkung Jonathan Bennett: Vorhergesehene Nebenwirkungen vs. beabsichtigte Folgen Ralph Wedgwood: Zur Verteidigung der Lehre von der Doppelwirkung -/- 7. Moralische Rechte H. L. A. Hart: Gibt es natürliche Rechte? Joseph Raz: Über die Beschaffenheit von Rechten -/- 8. Moralischer Zufall Thomas Nagel: Moralischer Zufall Susan Wolf: Die Moral des moralischen Zufalls. (shrink)

Jusqu'au IXe siècle, en Orient où l'Empire romain perdure comme en Occident où il n'existe plus, « l'Église » se pense et se vit sur le mode synodal, avec les nuances qu'apporte, ici, l'idéologie eusébienne, donnant le primat au « palais royal » sur le « siège apostolique », et, là, l'augustinienne, qui soutient l'inverse. Deux siècles plus tard, alors que l'Empire byzantin a cessé de prétendre à l'universalité romaine, la chrétienté latine occidentale ne rêve que de renovatio romani imperii, (...) à son bénéfice. Entre ces deux moments, il y a l'éphémère aventure de Gerbert d'Aurillac qui, après avoir défendu à Reims la cause des évêques contre le pape, devint, par la grâce d'Otton III, le pape de l'An Mil, Sylvestre II : c'était le nom que portait le pontife du temps de Constantin, auquel le nouvel empereur ne cesse de se référer, en souhaitant un empire moins germanique qu'universel. Ce dut être une grande joie, pour le pape, d'entendre Otton dire en 1001 : « Nous proclamons Rome capitale du monde et nous reconnaissons l'Église romaine comme mère de toutes les Églises. » Désormais, la communion n'est plus réglée par la lex communis ecclesiae catholicae, mais par 1'unius arbitrium et Sylvestre II parlera en « père universel », conscient d'exercer seul le ministère de Pierre. C'est dans ces fortes convictions que l'Église romaine affrontera la crise de la chrétienté des XIIIe-XIVe siècles. Up until the ninth century, when the Roman Empire continued in the East but ceased to exist in the West, « the Church » thought and lived in the synodal mode. The slight difference was that Eusebien ideology prevailed in the East, which gave primacy to the « royal palace » over the « apostolic seat », while Augustinien ideology held the contrary in the West. Two centuries later, when the Byzantine Empire ceased to pretend to Roman universality, western Latin Christianity dreamed only of the renewal of the Roman Empire, to its own advantage. Between these two moments, there was the ephemeral adventure of Gerbert of Aurillac who, after having defended the cause of the bishops against the pope at Reims, became pope Sylvester II in the year 1000, thanks to Otto III. Sylvester was the name of the pontiff at the time of Constantine, to whom the new emperor didn’t cease to compare himself in wishing an empire less Germanic than universal. It must have been a great joy for the pope to hear Otto say in 1001 : « We proclaim Rome the capital of the world and we recognize the Roman Church as mother of all the Churches. » In the future, communion was no longer regulated by the Catholic Church's common law, but by the unius arbitrium, and Sylvester II will speak as « universal father », conscious of exercising alone the ministry of Peter. It is with these strong convictions that the Roman Church would face the crisis of Christianity in the XIII and XIV centuries. (shrink)

It is argued that causal understanding originates in experiences of acting on objects. Such experiences have consistent features that can be used as clues to causal identification and judgment. These are singular clues, meaning that they can be detected in single instances. A catalog of 14 singular clues is proposed. The clues function as heuristics for generating causal judgments under uncertainty and are a pervasive source of bias in causal judgment. More sophisticated clues such as mechanism clues and repeated interventions (...) are derived from the 14. Research on the use of empirical information and conditional probabilities to identify causes has used scenarios in which several of the clues are present, and the use of empirical association information for causal judgment depends on the presence of singular clues. It is the singular clues and their origin that are basic to causal understanding, not multiple instance clues such as empirical association, contingency, and conditional probabilities. (shrink)

In the third of his Logical Investigations, Husserl draws an important distinction between two kinds of parts: the dependent parts like the redness of a visual datum or the squareness of a given picture, and the independent parts like the head of a horse or a brick in a wall. On his view, the distinction is to be understood in terms of a more fundamental notion, the notion of foundation. This paper is an attempt at clarifying that notion. Such attempts (...) have already been undertaken by Peter Simons and Kit Fine, and the paper also contains elements of comparison of our three sets of views. (shrink)

In this paper, we propose a framework capable of dealing with anaphora and ellipsis which is both general and algorithmic. This generality is ensured by the compination of two general ideas. First, we use a dynamic semantics which reperent effects using a monad structure. Second we treat scopes flexibly, extending them as needed. We additionally implement this framework as an algorithm which translates abstract syntax to logical formulas. We argue that this framework can provide a unified account of a large (...) number of anaphoric phenomena. Specifically, we show its effectiveness in dealing with pronominal and VP-anaphora, strict and lazy pronouns, lazy identity, bound variable anaphora, e-type pronouns, and cataphora. This means that in particular we can handle complex cases like Bach–Peters sentences, which require an account dealing simultaneously with several phenomena. We use Haskell as a meta-language to present the theory, which also consitutes an implementation of all the phenomena discussed in the paper. To demonstrate coverage, we propose a test suite that can be used to evaluate computational approaches to anaphora. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Close Enemies: The Relationship of Psychiatry and Psychology in the Assessment of Mental DisordersPhilippe Le Moigne, PhDAs Peter Zachar rightly points out in his comment, the assessment of mental disorders underwent new developments with the release of the Diagnostic and Statistical Manual of Mental Disorders-V in 2013 (American Psychiatric Association, 2013). Whereas in 1980, the manual had been thought of in a rigorously categorical way, on the basis (...) of distinct and closed syndromic entities, this new version advocated the development of a radically dimensionalist approach, with the diagnosis aiming this time to restore the whole symptomatological picture of the patient on a spectrum of ratings are supposed to cover the entirety of psychiatric semiology (American Psychiatric Association, 2013).For its part, my article aimed to show how standardized assessment, guided by the return of psychiatry’s authority and the assertion of its legitimacy in the diagnostic field, gave the ascendancy in the 1980s to the classificatory tradition and thus to the categorical model, to the detriment of personality approach and test psychology which offered a competing solution here. This perspective, historically dated, may have led the reader to think that there is an antagonism that cannot be overcome here. Rather, it should be seen as a form of structuring opposition, or even a “complementarity inscribed in rivalry,” between psychiatry and psychology, which is naturally susceptible to change over time.Indeed, the reversal operated by the Diagnostic and Statistical Manual of Mental Disorders-V is not total because it cannot be total. The defense of the dimensionalist approach, dear to the psychological testing tradition, was intended here to allow the identification of co-morbidities, present in most patients but poorly apprehended by the categorical approach, and to open up diagnosis to prevention by screening for minor manifestations of psychopathology when they suggest the [End Page 259] development of a manifest episode of the disease in the more or less long term. The risk here is that we end up with overdiagnosis and thus an over-representation of false positives (Wakefield, 2015). In other words, this type of approach does not escape the obligation to determine threshold scores, likely to indicate the lower limit of the disorder, and thus to resort to a categorical approach. There is a first affinity between the two perspectives which obeys, beyond the divergences in principle, a technical requirement.But the two approaches have even more in common when we look at their epistemological background: they share the idea that the representation and the intervention on mental disorder, to use Ian Hacking’s expression (1983), must be based on the model proposed by the physical and natural sciences. And as Greta Kaluzeviciute aptly points out in her comment, this orientation leads to the idea of measuring mental disorder in particular to conduct elaborate quantification operations to determine, for example, whether two entities are statistically distinct or whether a drug has a significant effect on the evolution of a pathology.This is in fact an old question that can be formulated as follows, to use the expression of the psychometrician Joel Michell (1999): are psychological dimensions metric? In other words, if we want to apply the language of numbers to mental disorders, they must share its properties, two of which seem essential: it must be possible to establish that each mental disorder, in the same way as qualities attributable to length for example, has a zero and can be divided by means of gradients (or degrees of intensity) whose interval is constant (Le Moigne, 2018; Michell, 1999). For lack of space, let us only address the second condition. This one has already been denied by many, starting with Bergson at the end of the nineteenth century (1889). He does not believe in the quantification of psychological expressions, starting with sensations. What is the common point, he wrote, between the feeling of a mild pain, as one feels a stiffness, and the sensation of a needle being hammered into your flesh? For him, one and the other of these intensities are incomparable, so that they do not belong to a similar register of sensations that one could stage from a 0 toward a... (shrink)

Beginnings can be empirically described, philosophically debated, fictionally recounted or theatrically staged – each kind of discourse approaches beginnings via an examination of representation as an impossible return to source. The work of French philosopher Philippe Lacoue-Labarthe articulates the problem of beginnings by considering them as a form of subjective collapse, loss of integrity and aggravation of emotion resulting from the paradoxical logic of representation. While Lacoue-Labarthe’s position has been largely developed in his philosophical writings, this study focuses more specifically (...) on his literary production, namely his collection of short stories, L’ “Allégorie”, and his staged debate with Jean-Luc Nancy in Scène: suivi de Dialogue sur le dialogue, in which the two writers present opposing views on the theatre. The analysis of the above texts centres on the two key “locations” for beginnings, namely narrative voice and the theatrical stage. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Editors’ Introduction“Between the Bible and the Philosophers”: ShakespearePeter Atterton (bio) and Sean Lawrence (bio)It is not clear when Levinas first read Shakespeare, but we do have some clues. The first complete translation of Shakespeare’s works into Russian, Levinas’s mother tongue, appeared between 1865 and 1868. These volumes doubtless graced the shelves of his family’s bookstore in Kovno (now Kaunas), in Lithuania, then part of the Russian empire. Kovno served (...) as capital of one of three губернии gubernias (provinces), but also as the de facto center of Lithuanian intellectual life. The family bookstore catered to the highbrow tastes of government officials and served the needs of teachers and students at the local lycée. One also imagines that it fired the literary imagination of the young Levinas, who taught himself to read Russian at a young age. However, it would have been highly unusual for one so young, even for one as precocious as Levinas, to have read Shakespeare recreationally and self-educationally during this period (1906–1915). It probably was not until he entered the lycée in Kharkov, in Tsarist Ukraine, where his family emigrated at the beginning the Great War, or after his family’s return in 1920 to Lithuania, where Levinas attended the Hebrew lycée in Kovno, that Levinas read Shakespeare for the first time. We know that Russian gymnasiums and technical schools assigned Shakespeare.1 His gymnasium education, between the ages of eleven and seventeen, is therefore the latest point by which Levinas could have read Shakespeare for the first time, though we do not know what or how much.He certainly acknowledged Shakespeare’s influence on his early thought. In an interview broadcast on Radio France Culture in February 1981, Philippe Nemo asked Levinas what were “the first great books” he encountered, “the Bible or the philosophers?” Levinas answered by saying that he read the Bible while very young but only began to read philosophy with any seriousness at university. He proceeded, however, to volunteer a third category of great books, [End Page 1]between the Bible and the philosophers, the Russian classics—Pushkin, Lermontov, Gogol, Turgenev, Dostoyevsky and Tolstoy, and also the great writers of Western Europe, notably Shakespeare, much admired in Hamlet, Macbeth and King Lear.2If we treat this as a chronology, then Levinas would have first read Shakespeare at some time “between” the age of six, when he began reading the Bible and other Hebrew texts with a private tutor, and the age of seventeen, when he enrolled at the University of Strasbourg.A polyglot, Levinas could have read Shakespeare in English as well as in Russian translation, but also in French, German, or Hebrew translation. For that matter, he could have read it in Lithuanian translation.3 We don’t know which French edition he read first or drew upon most closely.4 In Time and the Other, he follows the translation of Émile Montégut for Macbeth but for Romeo and Juliet, as noted in Sean Lawrence’s article, he does not repeat verbatim any of the major translations. When he quotes Shakespeare in English, he follows an original spelling edition. In the notebooks that he kept during imprisonment, and part of which we have translated here, Levinas appears to quote Shakespeare in English from memory, but incorrectly.This error notwithstanding, the Carnets de captivité show the imprisoned Levinas reading widely in English. Perhaps he expected a victory by the anglo-phone powers, or perhaps he practiced a sort of defiance in reading the language of his captors’ enemies, or perhaps he sought to strengthen his understanding of one of the European languages he had neglected in the precocity of his youth. Besides Shakespeare, we find him reading D. H. Lawrence’s Lady Chatterley’s Lover and Charles Morgan’s Sparkenbroke within our selection. Elsewhere in the notebooks, he refers to Arthur Conan Doyle, Charles Dickens, L. Ryder Haggard, Maurice Baring, Millen Brand, Pearl Buck, and Edgar Allan Poe.5 His references range from the cursory—in the case of Brand’s The Outward Room, it consists only of its title and author—to the surprisingly detailed and suggestive. After reading... (shrink)

Philippe Michel-Thiriet's, published in 1999, contains beside biographical data a »lexicon of characters« and a »lexicon of places in the Recherche.« There is, however, no »lexicon of objects:« No directory of the furniture in the parlor of Madame Verdurin, no comment on the »enmity of the violet curtains« in the Hotel of Balbec, the Queen of Naple's forgotten fan or the hanging lamp in the dining room in Combray. Are these objects thus not part of the novel? Are they mere (...) accessories and requisites? Or are they simply not classifiable in the systematic categories of a lexicon? But why? The paper addresses these questions and tries to give the objects in the attention that usually only the novel's protagonists receive. At the same time, it deals with the legacies of Proust's existence that are occasionally identified with the objects in the novel. But how can a real object enter a novel? And does it ever find its way back out? (shrink)

In this conversation, Brazilian anthropologist, philosopher, and political activist Eduardo Viveiros de Castro offers an overview of his thinking, both past and present. After explaining why initially he argued that ontology should be a topic of anthropologists, he discusses his more recent conclusion that indigenous thought should be regarded instead as metaphysical. It is not that la pensée sauvage has an implicit ontology discoverable by the human sciences but, rather, that indigenous people themselves think about metaphysical issues as such. He (...) explains the origins of this position in the ethnographic fieldwork that he undertook in the 1980s with the Awareté of northwestern Brazil and in his and the anthropologist Philippe Descola's parallel engagements with the structuralism of Claude Lévi-Strauss. Finally, Viveiros de Castro addresses the political stakes of ascribing metaphysics to alien and marginal peoples, clarifying what he means by the “permanent decolonization of thought.”. (shrink)

Das 1999 veröffentlichte Proust-Lexikon von Philippe Michel-Thiriet umfasst neben zahlreichen biographischen Daten ein »Lexikon der Personen in der Recherche« sowie ein »Lexikon der Orte der Recherche«. Es gibt jedoch kein Lexikon der Dinge der Recherche: kein Verzeichnis der Möbel im Salon von Madame Verdurin, keine Notiz zur »Feindseligkeit der violetten Vorhänge« im Hotel in Balbec, zum vergessenen Fächer der Königin von Neapel oder der Hängelampe im Esszimmer von Combray. Gehören diese Dinge demnach nicht dazu? Handelt es sich um Uneigentliches, um (...) Beiwerk oder Requisiten? Oder sind diese Objekte im Ordnungssystem eines Lexikons einfach nicht adressierbar? Aber warum? Der Beitrag geht diesen Fragen nach und versucht, den Gegenständen in À la recherche du temps perdu die gleiche Aufmerksamkeit zu schenken, die in der Regel nur den handelnden Charakteren des Romans gewidmet wird. Zugleich geht es um die Hinterlassenschaften von Prousts Existenz, die gelegentlich mit Dingen im Roman identifiziert wurden. Aber wie kann ein reales Ding in einen Roman eingehen? Und findet es jemals wieder heraus? Philippe Michel-Thiriet's, published in 1999, contains beside biographical data a »lexicon of characters« and a »lexicon of places in the Recherche.« There is, however, no »lexicon of objects:« No directory of the furniture in the parlor of Madame Verdurin, no comment on the »enmity of the violet curtains« in the Hotel of Balbec, the Queen of Naple's forgotten fan or the hanging lamp in the dining room in Combray. Are these objects thus not part of the novel? Are they mere accessories and requisites? Or are they simply not classifiable in the systematic categories of a lexicon? But why? The paper addresses these questions and tries to give the objects in the attention that usually only the novel's protagonists receive. At the same time, it deals with the legacies of Proust's existence that are occasionally identified with the objects in the novel. But how can a real object enter a novel? And does it ever find its way back out? (shrink)

The iconoclastic Brazilian anthropologist and theoretician Eduardo Viveiros de Castro, well known in his discipline for helping initiate its “ontological turn,” offers a vision of anthropology as “the practice of the permanent decolonization of thought.” After showing that Amazonian and other Amerindian groups inhabit a radically different conceptual universe than ours—in which nature and culture, human and nonhuman, subject and object are conceived in terms that reverse our own—he presents the case for anthropology as the study of such “other” metaphysical (...) schemes, and as the corresponding critique of the concepts imposed on them by the human sciences. Along the way, he spells out the consequences of this anthropology for thinking in general via a major reassessment of the work of Claude Lévi-Strauss, arguments for the continued relevance of Deleuze and Guattari, dialogues with the work of Philippe Descola, Bruno Latour, and Marilyn Strathern, and inventive treatments of problems of ontology, translation, and transformation. Bold, unexpected, and profound, _Cannibal Metaphysics_ is one of the chief works marking anthropology’s current return to the theoretical center stage. (shrink)

The Hegel Lectures SeriesSeries Editor: Peter C. Hodgson Hegel's lectures have had as great a historical impact as the works he himself published. Important elements of his system are elaborated only in the lectures, especially those given in Berlin during the last decade of his life. The original editors conflated materials from different sources and dates, obscuring the development and logic of Hegel's thought. The Hegel Lectures series is based on a selection of extant and recently discovered transcripts and (...) manuscripts. The original lecture series are reconstructed so that the structure of Hegel's argument can be followed. Each volume presents an accurate new translation accompanied by an editorial introduction and annotations on the text, which make possible the identification of Hegel's many allusions and sources. Lectures on the Proofs of the Existence of GodHegel lectured on the proofs of the existence of God as a separate topic in 1829. He also discussed the proofs in the context of his lectures on the philosophy of religion, where the different types of proofs were considered mostly in relation to specific religions. The text that he prepared for his lectures in 1829 was a fully formulated manuscript and appears to have been the first draft of a work that he intended to publish and for which he signed a contract shortly before his death in 1831. The 16 lectures include an introduction to the problem of the proofs and a detailed discussion of the cosmological proof. Philipp Marheineke published these lectures in 1832 as an appendix to the lectures on the philosophy of religion, together with an earlier manuscript fragment on the cosmological proof and the treatment of the teleological and ontological proofs as found in the 1831 philosophy of religion lectures. Hegel's 1829 lectures on the proofs are of particular importance because they represent what he actually wrote as distinct from auditors' transcriptions of oral lectures. Moreover, they come late in his career and offer his final and most seasoned thinking on a topic of obvious significance to him, that of the reality status of God and ways of knowing God. These materials show how Hegel conceived the connection between the cosmological, teleological, and ontological proofs. All of this material has been newly translated by Peter C. Hodgson from the German critical editions by Walter Jaeschke. This edition includes an editorial introduction, annotations on the text, and a glossary and bibliography. (shrink)