32 found
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  1.  7
    Researcher Perspectives on Ethical Considerations in Adaptive Deep Brain Stimulation Trials.Katrina A. Muñoz, Kristin Kostick, Clarissa Sanchez, Lavina Kalwani, Laura Torgerson, Rebecca Hsu, Demetrio Sierra-Mercado, Jill O. Robinson, Simon Outram, Barbara A. Koenig, Stacey Pereira, Amy McGuire, Peter Zuk & Gabriel Lázaro-Muñoz - 2020 - Frontiers in Human Neuroscience 14.
  2.  21
    DBS and Autonomy: Clarifying the Role of Theoretical Neuroethics.Peter Zuk & Gabriel Lázaro-Muñoz - 2021 - Neuroethics 14 (1):83-93.
    In this article, we sketch how theoretical neuroethics can clarify the concept of autonomy. We hope that this can both serve as a model for the conceptual clarification of other components of PIAAAS and contribute to the development of the empirical measures that Gilbert and colleagues [1] propose.
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  3.  17
    Looking for Trouble: Preventive Genomic Sequencing in the General Population and the Role of Patient Choice.Gabriel Lázaro-Muñoz, John M. Conley, Arlene M. Davis, Marcia Van Riper, Rebecca L. Walker & Eric T. Juengst - 2015 - American Journal of Bioethics 15 (7):3-14.
    Advances in genomics have led to calls for developing population-based preventive genomic sequencing programs with the goal of identifying genetic health risks in adults without known risk factors. One critical issue for minimizing the harms and maximizing the benefits of PGS is determining the kind and degree of control individuals should have over the generation, use, and handling of their genomic information. In this article we examine whether PGS programs should offer individuals the opportunity to selectively opt out of the (...)
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  4.  12
    Researcher Perspectives on Data Sharing in Deep Brain Stimulation.Peter Zuk, Clarissa E. Sanchez, Kristin Kostick, Laura Torgerson, Katrina A. Muñoz, Rebecca Hsu, Lavina Kalwani, Demetrio Sierra-Mercado, Jill O. Robinson, Simon Outram, Barbara A. Koenig, Stacey Pereira, Amy L. McGuire & Gabriel Lázaro-Muñoz - 2020 - Frontiers in Human Neuroscience 14.
    The expansion of research on deep brain stimulation and adaptive DBS raises important neuroethics and policy questions related to data sharing. However, there has been little empirical research on the perspectives of experts developing these technologies. We conducted semi-structured, open-ended interviews with aDBS researchers regarding their data sharing practices and their perspectives on ethical and policy issues related to sharing. Researchers expressed support for and a commitment to sharing, with most saying that they were either sharing their data or would (...)
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  5.  11
    Neuroethics at 15: Keep the Kant but Add More Bacon.Gabriel Lázaro-Muñoz, Peter Zuk, Stacey Pereira, Kristin Kostick, Laura Torgerson, Demetrio Sierra-Mercado, Mary Majumder, J. Blumenthal-Barby, Eric A. Storch, Wayne K. Goodman & Amy L. McGuire - 2019 - American Journal of Bioethics Neuroscience 10 (3):97-100.
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  6.  7
    DBS and Autonomy: Clarifying the Role of Theoretical Neuroethics.Peter Zuk & Gabriel Lázaro-Muñoz - 2021 - Neuroethics 14 (1):83-93.
    In this article, we sketch how theoretical neuroethics can clarify the concept of autonomy. We hope that this can both serve as a model for the conceptual clarification of other components of PIAAAS and contribute to the development of the empirical measures that Gilbert and colleagues [1] propose.
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  7.  15
    Alienation, Quality of Life, and DBS for Depression.Peter Zuk, Amy L. McGuire & Gabriel Lázaro-Muñoz - 2018 - American Journal of Bioethics Neuroscience 9 (4):223-225.
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  8.  14
    Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies.Vinata Vedam-Mai, Karl Deisseroth, James Giordano, Gabriel Lazaro-Munoz, Winston Chiong, Nanthia Suthana, Jean-Philippe Langevin, Jay Gill, Wayne Goodman, Nicole R. Provenza, Casey H. Halpern, Rajat S. Shivacharan, Tricia N. Cunningham, Sameer A. Sheth, Nader Pouratian, Katherine W. Scangos, Helen S. Mayberg, Andreas Horn, Kara A. Johnson, Christopher R. Butson, Ro’ee Gilron, Coralie de Hemptinne, Robert Wilt, Maria Yaroshinsky, Simon Little, Philip Starr, Greg Worrell, Prasad Shirvalkar, Edward Chang, Jens Volkmann, Muthuraman Muthuraman, Sergiu Groppa, Andrea A. Kühn, Luming Li, Matthew Johnson, Kevin J. Otto, Robert Raike, Steve Goetz, Chengyuan Wu, Peter Silburn, Binith Cheeran, Yagna J. Pathak, Mahsa Malekmohammadi, Aysegul Gunduz, Joshua K. Wong, Stephanie Cernera, Aparna Wagle Shukla, Adolfo Ramirez-Zamora, Wissam Deeb, Addie Patterson, Kelly D. Foote & Michael S. Okun - 2021 - Frontiers in Human Neuroscience 15.
    We estimate that 208,000 deep brain stimulation devices have been implanted to address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters pooled data and determined that DBS expanded in its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. The DBS Think Tank was founded in 2012 providing a space where clinicians, engineers, researchers from industry and academia discuss current and emerging DBS technologies and logistical and ethical issues facing the field. The (...)
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  9.  15
    Ethical Analysis of “Mind Reading” or “Neurotechnological Thought Apprehension”: Keeping Potential Limitations in Mind.Peter Zuk & Gabriel Lázaro-Muñoz - 2019 - American Journal of Bioethics Neuroscience 10 (1):32-34.
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  10.  5
    Neural Safeguards Against Global Impacts of Memory Modification on Identity: Ethical and Practical Considerations.Kristin Marie Kostick & Gabriel Lázaro-Muñoz - 2021 - American Journal of Bioethics Neuroscience 12 (1):45-48.
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  11.  5
    Testimonial Injustice: Considering Caregivers in Paediatric Behavioural Healthcare.Michelle Trang Pham, Eric A. Storch & Gabriel Lázaro-Muñoz - 2021 - Journal of Medical Ethics 47 (11):738-739.
    Harcourt argues that in clinical contexts, children and young people with mental health illness can experience epistemic, specifically testimonial, injustice when their perspectives are unjustifiably discounted by health service providers.1 Our goal in this commentary was to illustrate how caregivers, a critical component of CYP treatment triad, can also engage in testimonial injustice towards CYP patients. Testimonial injustice occurs when one suffers a credibility deficit and that credibility deficit is based on prejudice.2 Harcourt expands Fricker’s account of testimonial injustice by (...)
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  12.  11
    Responsible Translation of Psychiatric Genetics and Other Neuroscience Developments: In Need of Empirical Bioethics Research.Gabriel Lázaro-Muñoz - 2017 - American Journal of Bioethics 17 (4):33-35.
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  13.  23
    The Fiduciary Relationship Model for Managing Clinical Genomic “Incidental” Findings.Gabriel Lázaro-Muñoz - 2014 - Journal of Law, Medicine and Ethics 42 (4):576-589.
    This paper examines how the application of legal fiduciary principles , can serve as a framework to promote management of clinical genomic “incidental” or secondary target findings that is patient-centered and consistent with recognized patient autonomy rights. The application of fiduciary principles to the clinical genomic testing context gives rise to at least four physician fiduciary duties in conflict with recent recommendations by the American College of Medical Genetics and Genomics . These recommendations have generated much debate among lawyers, clinicians, (...)
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  14.  22
    Could Genetic Enhancement Really Lead to Obsolescence?Gabriel Lázaro-Muñoz, Kristin M. Kostick & Peter Zuk - 2019 - American Journal of Bioethics 19 (7):34-36.
    Volume 19, Issue 7, July 2019, Page 34-36.
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  15.  18
    The Fiduciary Relationship Model for Managing Clinical Genomic “Incidental” Findings.Gabriel Lázaro-Muñoz - 2014 - Journal of Law, Medicine and Ethics 42 (4):576-589.
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  16.  7
    Ethical and Social Considerations for Increasing Use of DTC Neurotechnologies.Kristin M. Kostick, Demetrio Sierra-Mercado & Gabriel Lázaro-Muñoz - 2019 - American Journal of Bioethics Neuroscience 10 (4):183-185.
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  17.  35
    Genomic Contraindications for Heart Transplantation.Danton S. Char, Gabriel Lázaro-Muñoz, Aliessa Barnes, David Magnus, Michael J. Deem & John D. Lantos - 2017 - Pediatrics 139 (4).
  18.  12
    Operationalizing Agency in Brain Computer Interface (BCI) Research.Kristin Kostick, Peter Zuk & Gabriel Lázaro-Muñoz - 2021 - American Journal of Bioethics Neuroscience 12 (2-3):203-205.
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  19.  2
    Researcher Views on Changes in Personality, Mood, and Behavior in Next-Generation Deep Brain Stimulation.Peter Zuk, Clarissa E. Sanchez, Kristin Kostick-Quenet, Katrina A. Muñoz, Lavina Kalwani, Richa Lavingia, Laura Torgerson, Demetrio Sierra-Mercado, Jill O. Robinson, Stacey Pereira, Simon Outram, Barbara A. Koenig, Amy L. McGuire & Gabriel Lázaro-Muñoz - forthcoming - American Journal of Bioethics Neuroscience:1-13.
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  20.  7
    Pediatric Deep Brain Stimulation for Dystonia: Current State and Ethical Considerations.Katrina A. Muñoz, Jennifer Blumenthal-Barby, Eric A. Storch, Laura Torgerson & Gabriel Lázaro-muñoz - 2020 - Cambridge Quarterly of Healthcare Ethics 29 (4):557-573.
    Dystonia is a movement disorder that can have a debilitating impact on motor functions and quality of life. There are 250,000 cases in the United States, most with childhood onset. Due to the limited effectiveness and side effects of available treatments, pediatric deep brain stimulation has emerged as an intervention for refractory dystonia. However, there is limited clinical and neuroethics research in this area of clinical practice. This paper examines whether it is ethically justified to offer pDBS to children with (...)
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  21.  7
    Is Real-Time ELSI Realistic?John M. Conley, Anya E. R. Prince, Arlene M. Davis, Jean Cadigan & Gabriel Lazaro-Munoz - 2020 - Ajob Empirical Bioethics 11 (2):134-144.
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  22.  6
    Treatment Search Fatigue and Informed Consent.Peter Zuk & Gabriel Lázaro-Muñoz - 2021 - American Journal of Bioethics Neuroscience 12 (1):77-79.
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  23.  6
    Reconceptualizing Triage to Incorporate Principles of Risk and Uncertainty: An Example From Deep Brain Stimulation Patients with Treatment-Resistant Disorders.Lavina Kalwani, Kristin Kostick, Eric A. Storch & Gabriel Lázaro-Muñoz - 2020 - American Journal of Bioethics 20 (7):207-209.
    Volume 20, Issue 7, July 2020, Page 207-209.
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  24.  5
    The Ethics of Getting Ahead When All Heads Are Enhanced.Kristin Marie Kostick, J. S. Blumenthal-Barby, Eric A. Storch & Gabriel Lázaro-Muñoz - 2020 - American Journal of Bioethics Neuroscience 11 (4):256-258.
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  25.  13
    Scientific Social Responsibility: Lessons From the Corporate Social Responsibility Movement.John M. Conley, Gabriel Lázaro-Muñoz, Anya E. R. Prince, Arlene M. Davis & R. Jean Cadigan - 2015 - American Journal of Bioethics 15 (12):64-66.
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  26.  8
    Enhance Diversity Among Researchers to Promote Participant Trust in Precision Medicine Research.Demetrio Sierra-Mercado & Gabriel Lázaro-Muñoz - 2018 - American Journal of Bioethics 18 (4):44-46.
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  27.  12
    Automatic Placement of Genomic Research Results in Medical Records: Do Researchers Have a Duty? Should Participants Have a Choice?Anya E. R. Prince, John M. Conley, Arlene M. Davis, Gabriel Lázaro-Muñoz & R. Jean Cadigan - 2015 - Journal of Law, Medicine and Ethics 43 (4):827-842.
    The growing practice of returning individual results to research participants has revealed a variety of interpretations of the multiple and sometimes conflicting duties that researchers may owe to participants. One particularly difficult question is the nature and extent of a researcher’s duty to facilitate a participant’s follow-up clinical care by placing research results in the participant’s medical record. The question is especially difficult in the context of genomic research. Some recent genomic research studies — enrolling patients as participants — boldly (...)
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  28.  11
    Response to Open Peer Commentaries on “Looking for Trouble: Preventive Genomic Sequencing in the General Population and the Role of Patient Choice”.Gabriel Lázaro-Muñoz, John M. Conley, Arlene M. Davis, Marcia Van Riper, Rebecca L. Walker & Eric T. Juengst - 2015 - American Journal of Bioethics 15 (12):6-9.
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  29.  1
    Researchers’ Ethical Concerns About Using Adaptive Deep Brain Stimulation for Enhancement.Kristin Kostick-Quenet, Lavina Kalwani, Barbara Koenig, Laura Torgerson, Clarissa Sanchez, Katrina Munoz, Rebecca L. Hsu, Demetrio Sierra-Mercado, Jill Oliver Robinson, Simon Outram, Stacey Pereira, Amy McGuire, Peter Zuk & Gabriel Lazaro-Munoz - 2022 - Frontiers in Human Neuroscience 16.
    The capacity of next-generation closed-loop or adaptive deep brain stimulation devices to read and write shows great potential to effectively manage movement, seizure, and psychiatric disorders, and also raises the possibility of using aDBS to electively modulate mood, cognition, and prosociality. What separates aDBS from most neurotechnologies currently used for enhancement is that aDBS remains an invasive, surgically-implanted technology with a risk-benefit ratio significantly different when applied to diseased versus non-diseased individuals. Despite a large discourse about the ethics of enhancement, (...)
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  30.  5
    Automatic Placement of Genomic Research Results in Medical Records: Do Researchers Have a Duty? Should Participants Have a Choice?Anya E. R. Prince, John M. Conley, Arlene M. Davis, Gabriel Lázaro-Muñoz & R. Jean Cadigan - 2015 - Journal of Law, Medicine and Ethics 43 (4):827-842.
    The growing practice of returning individual results to research participants has revealed a variety of interpretations of the multiple and sometimes conflicting duties that researchers may owe to participants. One particularly difficult question is the nature and extent of a researcher’s duty to facilitate a participant’s follow-up clinical care by placing research results in the participant’s medical record. The question is especially difficult in the context of genomic research. Some recent genomic research studies — enrolling patients as participants — boldly (...)
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  31.  1
    Research Comparing iPSC-Derived Neural Organoids to Ex Vivo Brain Tissue of Postmortem Donors: Identity After Life?Peter Zuk, Laura Stertz, Consuelo Walss-Bass & Gabriel Lázaro-Muñoz - 2022 - American Journal of Bioethics Neuroscience 13 (2):111-113.
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  32.  1
    Capacities and Limitations of Using Polygenic Risk Scores for Reproductive Decision Making.Gabriel Lázaro-Muñoz, Stacey Pereira, Meghna Mukherjee, Kristin Marie Kostick-Quenet, Shai Carmi, Todd Lencz & Dorit Barlevy - 2022 - American Journal of Bioethics 22 (2):42-45.
    In their article “Implementing Expanded Prenatal Genetic Testing: Should Parents Have Access to Any and All Fetal Genetic Information?” Bayefsky and Berkman briefly mention that: “[s]ome are...
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