The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO) project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to (...) existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI) and Phenotype Attribute and Trait Ontology (PATO) without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology) and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT)). The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource providing details on the people, policies, and issues being addressed in association with OBI. (shrink)

Numerous studies suggest that both emotion knowledge and language abilities are powerfully related to young children’s theory of mind. Nonetheless, the magnitude and direction of the associations between language, emotion knowledge, and theory-of-mind performance in the first years of life are still debated. Hence, the aim of this study was to assess the direct effects of emotion knowledge and language on theory-of-mind scores in 2- and 3-year-old children. A sample of 139 children, aged between 24 and 47 months ( M (...) = 35.5 months; SD = 6.73), were directly administered measures of emotion knowledge, theory of mind, and language. We conducted structural equation modeling (SEM) to evaluate the effects of these variables within a single comprehensive framework, while also controlling for any effects of age and gender. The proposed structural equation model provided an excellent fit for the data, indicating that both children’s emotion knowledge, and their language ability had direct positive effects on theory of mind scores. In addition, age was found to wield statistically significant effects on all the variables under study, whereas gender was not significantly associated with any of them. These findings suggest the importance of fostering young children’s emotion knowledge and language ability with a view to enhancing their comprehension of mental states. (shrink)

In the 1950s, long before his ascent to international renown, Michel Foucault published a scant few works. His early writings on psychology, psychopathology, and anthropology have been dismissed as immature. However, recently discovered manuscripts from the mid-1950s, when Foucault was a lecturer at the University of Lille, testify to the significance of the work that the philosopher produced in the years leading up to the “archaeological” project he launched with History of Madness. Elisabetta Basso offers a groundbreaking and in-depth (...) analysis of Foucault’s Lille manuscripts that sheds new light on the origins of his philosophical project. She considers the epistemological style and methodology of these writings as well as their philosophical context and the scholarly networks in which Foucault was active, foregrounding his relationship to existential psychiatry. Young Foucault blurs the boundaries between biography and theory, exploring the transformations—and, at times, contradictions—that characterize the intellectual trajectory of a philosopher who, as Foucault himself put it, “turned to psychology, and from psychology to history.” Retracing the first steps of the philosopher’s intellectual journey, Basso shows how Foucault’s early writings provide key insights into his archaeological work of the 1960s. Assembling a vast array of archival sources—including manuscripts, reading notes, notes for lectures and conferences, and correspondence—this book develops a new and deeper understanding of Foucault’s body of work. (shrink)

This commentary focuses on Machery's eliminativist claim, that ought to be eliminated from the theoretical vocabulary of psychology because it fails to denote a natural kind. I argue for the more traditional view that concepts are a functional kind, which provides the simplest account of the empirical evidence discussed by Machery.

Nel nostro mondo occidentale e urbanizzato i bambini subiscono forme di segregazione e controllo, al pari di altre categorie sociali altrettanto ‘scomode', perché ostacolano il cosiddetto ‘ordine morale del profitto e del consumo'. La casa, la scuola, i luoghi strutturati e sorvegliati delle attivitÀ del tempo libero, vengono presentati come il rifugio contro i pericoli della strada che č perciň interdetta ai bambini con ogni mezzo, compreso il coprifuoco. Ma la libera fruizione di uno spazio pubblico fatto di strade, piazze, (...) slarghi, aree vuote e marginali, č invece fondamentale per lo sviluppo delle capacitÀ sociali dei bambini. Uno dei tre principi della Carta ONU dei Diritti dell'infanzia, quello alla partecipazione e all'autonomia, č violato. (shrink)

This book provides an introduction to the study of words, their main properties and how we use them to create meaning. It offers a detailed description of the organizational principles of the lexicon, and of the categories used to classify various lexical phenomena, including polysemy, meaning variation, behaviour in composition, and the interface with pragmatics. Elisabetta Ježek uses empirical data from digitalized corpora and speakers' judgements, combined with the formalisms developed in the field of general and theoretical linguistics, to (...) propose representations for each of these phenomena. The book's clear structure and accessible approach make it an ideal textbook for all students of linguistics and a valuable resource for scholars and students of language in the fields of cognitive science and philosophy. (shrink)

This book provides an introduction to the study of words, and how we use words to create meaning. It offers an accessible description of the main properties of words and the organizational principles of the lexicon, based on theoretical accounts and extensive empirical data.

There is a lot of conceptual engineering going on in medical research. I substantiate this claim with two examples, the medical debate about cancer classification and about obesity as a disease I also argue that the proper target of conceptual engineering in medical research are experts’ conceptions. These are explicitly written down in documents and guidelines, and they bear on research and policies. In the second part of the chapter, I propose an externalist framework in which conceptions have both the (...) explanatory power of psychological concepts and that of semantic concepts. It is likely, however, that human activities and practices distinct from medical research, and regulated by different practices and epistemic rules, call for different targets for conceptual engineering. I conclude with indicating an open agenda of problems for philosophers of medicine interested in conceptual engineering. (shrink)

This paper focuses on one of the original moments of the development of the “phenomenological” current of psychiatry, namely, the psychopathological research of Ludwig Binswanger. By means of the clinical and conceptual problem of schizophrenia as it was conceived and developed at the beginning of the twentieth century, I will try to outline and analyze Binswanger’s perspective from a both historical and epistemological point of view. Binswanger’s own way means of approaching and conceiving schizophrenia within the scientific, medical, and psychiatric (...) context of that time will lead us to grasp the epistemological stakes at the origins of his project of reforming psychiatry by means of phenomenology. I will finally attempt to upgrade and update Binswanger’s project in light of the current reappraisal of phenomenology within the ongoing debate on psychopathology engaged by studies in the field of science and philosophy of mind. (shrink)

The distinction between concept and conception has been widely debated in political philosophy, whereas in the philosophy of psychology is frequently used, but rarely focused on. This paper aims at filling in this lacuna. I claim that far from being explanatorily idle, the distinction makes it possible to provide an adequate description of phenomena such as genuine disagreement, and concept contestation, which would otherwise remain implausibly puzzling. I illustrate and assess three accounts of the concept-conception distinction. Finally I propose a (...) social externalist account, which relies on deference to experts, and builds on Tyler Burge’s ideas of many decades ago. The debate on concepts and conceptions thus shows a connection with the increasing research work on experts and expertise in psychology and social epistemology. (shrink)

This paper explores the possibility of resisting meaning scepticism – the thesis that there are many alternative incompatible assignments of reference to each of our terms - by appealing to the idea that the nature of reference is to maximize knowledge. If the reference relation is a knowledge maximizing-relation, then some candidate referents are privileged among the others - i.e., those referents we are in a position to know about – and a positive reason against meaning scepticism is thus individuated. (...) A knowledge-maximizing principle on the nature of reference was proposed by Williamson in a recent paper (Williamson 2005). According to Williamson, such a principle would count as a defeasible reason for thinking that most of our beliefs tend to be true. My paper reverses Williamson’s dialectic, and argues that reference is knowledge-maximizing from the premise that most of our beliefs tend to be true. (shrink)

Based on the empirical findings correlating disgust with conservatism, most disgust scholars have fed arguments for its moral unreliability and concluded with moral condemnation of this emotion. In this paper, I will examine common arguments about whether relying on disgust in the moral domain is to be considered good or bad. I will problematize the suggestion that we are justified in firmly believing that disgust is an ethically «dumb» – or an ethically «smart» – emotion. It rather seems that moral (...) disgust can be rational or irrational, pro-social or anti-social, liberal or conservative depending on the eliciting contexts, and that such case-by-case conclusions rely on additional meta-ethical premises. (shrink)

Advanced medical imaging, such as CT, fMRI and PET, has undergone enormous progress in recent years, both in accuracy and utilization. Such techniques often bring with them an illusion of immediacy, the idea that the body and its diseases can be directly inspected. In this paper we target this illusion and address the issue of the reliability of advanced imaging tests as knowledge procedures, taking positron emission tomography in oncology as paradigmatic case study. After individuating a suitable notion of reliability, (...) we argue that PET is a highly theory-laden and non-immediate knowledge procedure, in spite of the photographic-like quality of the images it delivers; the diagnostic conclusions based on the interpretation of PET images are population-dependent; PET images require interpretation, which is inherently observer-dependent and therefore variable. We conclude with a three-step methodological proposal for enhancing the reliability of advanced medical imaging. (shrink)

Introduction: A general trend in the psychological literature suggests that guilt contributes to morality more than shame does. Unlike shame-prone individuals, guilt-prone individuals internalize the causality of negative events, attribute responsibility in the first person, and engage in responsible behavior. However, it is not known how guilt- and shame-proneness interact with the attribution of responsibility to others. -/- Methods: In two Web-based experiments, participants reported their attributions of moral culpability (i.e., responsibility, causality, punishment and decision-making) about morally ambiguous acts of (...) killing in different conditions. In Study 1 the vignettes were presented in the 1st person, while in Study 2 in the 3rd person. To test proneness to guilt and shame, we utilized the GASP scale, which differentiates between the affective and behavioral components of each emotion. Statistical analyses were performed in Matlab and R. -/- Results: We found that guilt- and shame-proneness were associated with the severity of attributions in both the first and the third person, but the effect was strong only in the guilt case (both subtypes) and shame-affect case, and not in the shame-behavior case. We call this the Moralizing Effect. -/- Discussion: We wonder whether our finding that guilt-prone people tend to attribute a higher degree of culpability to others is really consistent with the view that guilt motivates people to choose the “moral paths in life”. This echoes views about the harmful aspects of guilt, which have been expressed historically in philosophy, for example, by Friedrich Nietzsche. (shrink)

Baccarini and Malatesti (2017) defend the idea that we must use coercively biomedical means to enhance the morality of a specific group of individuals: psychopaths, diagnosed through the Psychopathy Checklist-Revised (PCL-R) standards (Hare, 2003). Their argument is theoretical, thus it goes independently from the actual effectiveness of existent treatments, and it is based on a logical reasoning. Moral bioenhancement (MB) means include psychotropic drugs, brain stimulations, neurosurgeries, genetic editing, etc. -/- In short, the authors apply Gerald Gaus' account of open (...) justification (Gaus, 1996, 2011), according to which “a prescription addressed to an agent is a reasoning that includes premises that consider the system of reasons (such as beliefs, preferences, etc.) of that agent” (Baccarini and Malatesti, 2017, p. 1). In their view, coercive MB of psychopaths is morally sound and deducible by reasons within the psychopath's cognitive-affective system—even if the psychopath needs not to be able to consciously or sincerely endorse them. We believe that this argument is flawed. In sum, we argue that the psychopath's cognitive-affective system would consistently justify reasons against mandatory MB to herself, even if she wishes differently for others, and that the prescription cannot be extended. (shrink)

A Kuhnian reformulation of the recent debate in psychiatric nosography suggested that the current psychiatric classification system (the DSM) is in crisis and that a sort of paradigm shift is awaited (Aragona, 2009). Among possible revolutionary alternatives, the proposed fi ve-axes etiopathogenetic taxonomy (Charney et al., 2002) emphasizes the primacy of the genotype over the phenomenological level as the relevant basis for psychiatric nosography. Such a position is along the lines of the micro-reductionist perspective of E. Kandel (1998, 1999), which (...) sees mental disorders reducible to explanations at a fundamental epistemic level of genes and neurotransmitters. This form of micro-reductionism has been criticized as a form of genetic-molecular fundamentalism (e.g. Murphy, 2006) and a multi-level approach, in the form of the burgeoning Cognitive Neuropsychiatry, was proposed. This article focuses on multi-level mechanistic explanations, coming from Cognitive Science, as a possible alternative etiopathogenetic basis for psychiatric classification. The idea of a mechanistic approach to psychiatric taxonomy is here defended on the basis of a better conception of levels and causality. Nevertheless some critical remarks of Mechanism as a psychiatric general view are also offered. (shrink)

Critics of clinical artificial intelligence (AI) suggest that the technology is ethically harmful because it may lead to the dehumanization of the doctor–patient relationship (DPR) by eliminating moral empathy, which is viewed as a distinctively human trait. The benefits of clinical empathy—that is, moral empathy applied in the clinical context—are widely praised, but this praise is often unquestioning and lacks context. In this article, I will argue that criticisms of clinical AI based on appeals to empathy are misplaced. As psychological (...) and philosophical research has shown, empathy leads to certain types of biased reasoning and choices. These biases of empathy consistently impact the DPR. Empathy may lead to partial judgments and asymmetric DPRs, as well as disparities in the treatment of patients, undermining respect for patient autonomy and equality. Engineers should consider the flaws of empathy when designing affective artificial systems in the future. The nature of sympathy and compassion (i.e., displaying emotional concern while maintaining some balanced distance) has been defended by some ethicists as more beneficial than perspective-taking in the clinical context. However, these claims do not seem to have impacted the AI debate. Thus, this article will also argue that if machines are programmed for affective behavior, they should also be given some ethical scaffolding. (shrink)

We raise a problem of applicability of RCTs to validate nuclear diagnostic imaging tests. In spite of the wide application of PET and other similar techniques that use radiopharmaceuticals for diagnostic purposes, RCT-based evidence on their validity is sparse. We claim that this is due to a general conceptual problem that we call Prevalence of Treatment, which arises in connection with designing RCTs for testing any diagnostic procedure in the present context of medical research, and is particularly apparent in this (...) case. We also identify three practical reasons why RCTs do not qualify as the best option for PET validation, which have to do with specific characteristics of nuclear diagnostic imaging, and of radiopharmaceuticals. The paper is meant to contribute both to the philosophical discussion on the EBM hierarchy of evidence, and on the specific debate on radiopharmaceuticals in nuclear medicine. (shrink)

The institution of “probation,” a form of judicial probation aimed for adults, was rewied by the recent justice reform law (Cartabia Reform, Dec. 30, 2022), where, even in the rewied version, was confirmed its high civic and reeducational value. Through probation, offenders can realize the paths to change own critical reinterpretation of their behavior. This is an interpretation of punishment that preserves its retributive value, but the challenge that institutions and associations take as welcoming these people into the activities and (...) projects of a (re)educational nature, gives this particular penal measure a restorative purpose too. Probation concerns first and foremost the offender, it also verifies the skills, resilience, and responsibility of those it accommodates. With these premises, in 2023 a collaboration between some professors of the Catholic University of the Sacred Heart and the Piacenza Volunteer Service Center led to the realization a training course and later a Research involving the Associations that take in the people on probation. (shrink)

Philosophical Psychology is dedicating this issue on trust and trustworthiness to Katherine Hawley (1971–2021) for two reasons. First, she was an expert in the area. Hawley was one of the most rele...

We give a description of the effect of the gravitational field by using the geodesic equation of motion with respect to a first order Finslerian approximation of the Minkowski metric. This motivates linking the physical force of gravity to the non flat nature of space in the Finslerian setting and leads to an anisotropic version of the red shift formula. We solve the linearized Finslerian field equations proposed by S.F. Rutz (Gen. Relativ. Gravit. 25(11):1139–1158, 1993).

Cet article présente et discute les textes du débat qui opposa, entre 1913 et 1914, Karl Jaspers et Ludwig Binswanger à propos du thème de la « méthode structurale » en psychopathologie (K. Jaspers, Allgemeine Psychopathologie, 1913 ; et « Kausale und “verständliche” Zusammenhänge zwischen Schicksal und Psychose bei der Dementia praecox – Schizophrenie » ; L. Binswanger, « Bemerkungen zu der Arbeit Jaspers’ “Kausale und “verständliche” Zusammenhänge zwischen Schicksal und Psychose bei der Dementia praecox (Schizophrenie)” », 1913 ; et (...) « Psychologische Tagesfragen innerhalb der klinischen Psychiatrie », 1914). L’enjeu est de montrer la diverse manière dont les deux auteurs adoptent la phénoménologie à partir de leur réception de la psychanalyse freudienne au début des années 1910. (shrink)

Résumé Cet article expose les tendances actuelles de ce nouveau domaine de recherche qu’est la « philosophie de la psychiatrie » à travers son évolution dans la dernière décade. La première partie se concentre sur le passage d’une approche strictement conceptuelle des thèses issues du savoir psychiatrique à une approche qui prend en compte également les dimensions sociales, pratiques et cliniques de cette discipline. La seconde partie de l’article montre comment l’exigence d’un engagement mutuel de la philosophie et de la (...) psychiatrie a été diversement perçue selon les pays engagés dans le programme de la philosophie de la psychiatrie. L’article s’intéresse en particulier à la France, où l’enthousiasme pour la « nouvelle philosophie de la psychiatrie » n’a pas eu le même retentissement sur la scène philosophique que dans les pays anglophones. Enfin cette contribution montre comment le domaine de la philosophie de la psychiatrie se présente comme un terrain fécond pour de nouvelles formes d’interaction entre la tradition analytique et la tradition continentale, en particulier à partir de la réflexion sur les thèmes de la normativité, du langage et de l’interprétation. (shrink)

This paper stresses the circumstance that Ferraris’ Documentalità shows that what is often improperly called “communication society” actually consists in a “recording society”. Recording is either a condition of the persistence of thought, and of the existence and the recognition of the social world, which expresses and settles itself in a configuration of documents. This perspective gets the notion of “spirit” out from its abstraction: without a letter, the spirit wouldn’t have any ontological consistence. What we call “spiritual” is the (...) result of registrations: as such, it has a foundational value and implies the responsibility for the acts that result from it. (shrink)