Similar to parasites, cancer cells depend on their hosts for sustenance, proliferation and reproduction, exploiting the hosts for energy and resources, and thereby impairing their health and fitness. Because of this lifestyle similarity, it is predicted that cancer cells could, like numerous parasitic organisms, evolve the capacity to manipulate the phenotype of their hosts to increase their own fitness. We claim that the extent of this phenomenon and its therapeutic implications are, however, underappreciated. Here, we review and discuss what can (...) be regarded as cases of host manipulation in the context of cancer development and progression. We elaborate on how acknowledging the applicability of these principles can offer novel therapeutic and preventive strategies. The manipulation of host phenotype by cancer cells is one more reason to adopt a Darwinian approach in cancer research. -/- . (shrink)

Workplace bullying is defined as repeated, malicious, and health-endangering mistreatment of an employee by one or more other employees. Workplace bullying has been associated with negative outcomes for the individual being bullied and for the organization in which such actions take place. This paper explains the nature, frequency, and costs of workplace bullying in the context of organizational culture, ethical culture, and organizational moral development. We also propose ways that organizations can and should deal with this increasingly common behavior.

The article represents a first approach of the campaign in the frenchspeakingradio and television. A thorough study will be done later. The topics examined here are: the impact of the campaign on the people; the organization of the campaign in the radio and television and the presentation of the different broadcastings in the national and the regional campaign; the topics of the campaign through the political platforms, the debates between several parties and the questions asked by the audience; the personalities (...) and «stars» during the campaign ; the audience and the campaign on RTL and in the press. (shrink)

Many political theorists have turned to the dramatic political events of the post-9/11 world – terrorism, war, and the erosion of civil liberties – for insight into our changing sense of the political. Yet few have examined the economic dimensions of these events or sought to learn what they might tell us about the changing nature of political community today. This article seeks to fill this gap by drawing on the work of Michel Foucault and Georgio Agamben to examine the (...) intimate and changing relationship between the political and the economic in the contemporary world. Now more than ever, there is a particular conception of politics at stake in global efforts to govern economic relations. Global economic institutions like the IMF and World Bank are policing the definition of political community and, in doing so, extending the scope of liberal governmentality. At the same time, the character of their implementation and justification is that of the sovereign exception, as state autonomy must continually be breached through extensive conditionality in order for it to be re-established in the form of a more ‘sound’ political and economic order. This is a sovereign exception with a difference: for the norm that is being established is one that necessarily limits the scope of sovereign power in the interests of market freedom. Paradoxically, while the economy is often the exception to politics as usual, is it an exception that simultaneously enables and constrains the possibility of exercising sovereignty itself? (shrink)

The article describes how an intellectual community of those following French trends in the academy have, for the past forty years, been offering a mistaken reading of Friedrich Nietzsche's concept of genealogy. The essay shows how Nietzsche mocks moral psychologists by calling them genealogists, contrasts Nietzsche's work with that of genealogists, and then documents how subsequent academics, encouraged by the work of Gilles Deleuze and, in turn, Michel Foucault, created a revaluation of genealogy's meaning, thereby fetishizing their own scholarly authority.

This article presents an analysis of visual-acoustic dissonance in Raise The Red Lantern ( Dà Hóng Dēnglóng Gāogāo Guà , Zhang Yimou, 1991). Drawing upon Michel Foucault's discussion of the Panopticon, this study argues that the camera in this film represents a panoptic entity whose subversion can only be achieved by means outside the visual economy. Sound is that means; the aural regime works consistently to unhinge the balance of the optical machinery on both a thematic and cinematographic level. By (...) coding the optical as a totalising and oppressive force, and subverting that force through various forms of visual-acoustic dissonance, Raise The Red Lantern unseats the traditionally dominant camera-image dyad, and presents a powerful rejection of the camera as the only life-giving force in an artistic medium that so privileges the visual. (shrink)

Ce recueil se veut un instrument de travail à l'intention de ceux qui s'interrogent sur les idéologies, ce qu'elles sont, d'où elles viennent et à quoi elles servent. Michel Simon y a réuni un certain nombre de textes qui ont marqué l'histoire et la réflexion sur l'idéologie et les idéologies et qui sont proposés comme autant de points de repères : Marx, Engels, Lénine, Lukacs, Mannheim, Korsch, Gramsci, Althusser chez les marxistes, mais aussi Jean Baechler et Pierre Ansart. Un (...) commentaire d'accompagnement situe ces textes dans leur contexte et fournit les explications nécessaires tandis que des tableaux récapitulatifs donnent une vue d'ensemble de chaque auteur. (shrink)

This book addresses central issues in the philosophy and metaphysics of science, namely the nature of scientific theories, their partial truth, and the necessity of scientific laws within a moderate realist and empiricist perspective. Accordingly, good arguments in favour of the existence of unobservable entities postulated by our best theories, such as electrons, must be inductively grounded on perceptual experience and not their explanatory power as most defenders of scientific realism claim. Similarly, belief in the reality of dispositions such as (...) causal powers which ground the natural necessity of scientific laws must be based on experience. Hence, this book offers a synthetic presentation of an original metaphysics of science, namely a metaphysics of properties, both categorical and dispositional, while at the same time opposing strong versions of necessitarism according to which laws are true in all possible worlds. The main theses and arguments are clearly presented in a non-technical way. Thus, on top of being of interest to the specialists of the topics discussed, it is also useful as a textbook in courses for third year and more advanced university students. (shrink)

This essay discusses an important early French response to the American Revolution, chapters 38-52 in Book 18 of Raynal and Diderot's Histoire des deux Indes (1780), and explores how this reponse was shaped by the influence of Montesquieu. In Raynal and Diderot's conception of political freedom, as in Montesquieu's, universalism is tempered by empiricism. Public opinion must never be ignored, local factors matter: the two philosophes praise the American revolutionaries for their wisdom in this respect. Clearly Montesquieuan in inspiration, the (...) American chapters of the Histoire des deux Indes constitute one of the most significant pre-revolutionary examples of moderate liberalism in France. (shrink)

One might be inclined to assume, given the mouse donning its cover, that the behavior of interest in Nicole Nelson's book Model Behavior (2018) is that of organisms like mice that are widely used as “stand-ins” for investigating the causes of human behavior. Instead, Nelson's ethnographic study focuses on the strategies adopted by a community of rodent behavioral researchers to identify and respond to epistemic challenges they face in using mice as models to understand the causes of disordered human behaviors (...) associated with mental illness. Although Nelson never explicitly describes the knowledge production activities in which her behavioral geneticist research subjects engage as “exemplary”, the question of whether or not these activities constitute “model behavior(s)”—generalizable norms for engaging in scientific research—is one of the many thought-provoking questions raised by her book. As a philosopher of science interested in this question, I take it up here. (shrink)

Whether the prefrontal cortex is part of the neural substrates of consciousness is currently debated. Against prefrontal theories of consciousness, many have argued that neural activity in the prefrontal cortex does not correlate with consciousness but with subjective reports. We defend prefrontal theories of consciousness against this argument. We surmise that the requirement for reports is not a satisfying explanation of the difference in neural activity between conscious and unconscious trials, and that prefrontal theories of consciousness come out of this (...) debate unscathed. (shrink)

Warum und wie genau darf zu Hause oder auf einer Theaterbühne anders gehandelt werden, als im Büro; wie verändert sich die Bedeutung von Worten, je nachdem wo, von wem und wie sie gesagt werden? Warum und mit welchen Mitteln versuchen wir, höflich zu sein, und inwiefern sind wir von unangemessenem Verhalten anderer bedroht? Welches Weltwissen benötigen Beobachter, um beurteilen zu können, wann Verhalten als angemessen oder unangemessen einzustufen ist? Im vorliegenden Band untersuchen die Beitragenden das Phänomen sozialer Angemessenheit unter anderem (...) aus philosophischer, sozialpsychologischer, soziologischer, kulturtheoretischer, linguistischer und anthropologischer Perspektive. Dabei werden insbesondere Bedingungen und Auswirkungen, Merkmale sowie Wandlungs- und Entstehungsprozesse sozialer Angemessenheit thematisiert. Die Herausgebenden Jacqueline Bellon M.A. promoviert an der TU Darmstadt und arbeitet als Philosophin, Kultur- und Sozialwissenschaftlerin. Dr. Bruno Gransche ist Philosoph am Institut für Technikzukünfte (ITZ) des Karlsruher Instituts für Technologie (KIT). Sebastian Nähr-Wagener M.A. ist wiss. Mitarbeiter am Institut für Technikzukünfte (ITZ) des Karlsruher Instituts für Technologie (KIT). (shrink)

To understand the political theory—and especially its alleged modernity—of Ogy Sorai, one of the most important philosophers of Tokugawa Japan, we need to understand the pivotal role that heaven, gods and spirits play in this theory. This is no easy task. This article will start with an analysis of the reasons of this difficulty: the numerous tensions and contradictions found in Sorai's remarks on the subject. Refusing to ignore one side of the story, refusing (...) also to reach too quickly a verdict of inconsistency, it also questions the rare attempt at a unified interpretation undertaken by Maruyama Masao. The article suggests that the solution is to understand that Sorai needs to speak from two different perspectives on the Way: the external perspective of the sages who grasp the relationships between the Way and the natural world as purveyor of the raw materials the Way is made of, and the internal perspective of commoners who must accept everything that is in a Way. This permits us to rescue the positivist interpretation of Sorai advanced by Maruyama and much criticized in recent years. (shrink)

Phenomena like the happiness of the wicked or the misfortune of the worthies were for Confucian thinkers, just as for Christian theologians, puzzles that their ‘theories on fortune and misfortune’, just like Theodicies in the West, were trying, with some difficulty, to explain or rationalize. This article first surveys some standard explanations of the phenomena given by scholars of eighteenth-century Japan within the framework of the available monist, rationalist paradigms. Afterward, it turns to another type of representation of the world (...) that could answer the puzzles—not, it should be stressed, by solving them, but rather by dis-solving them: by making them disappear as problems. In this new representation, for which many inhabitants of industrialized societies today have much affinity, the world in which humans live is ruled by many independent and mutually irreducible rationalities—economic, productive, military, moral (under various forms), political, physical, etc. If humans view the world in such manner, they are certainly confronted by many questions—for example the need to order or prioritize those logics in order to achieve an overarching order—but they are delivered at least of one burden: the necessity to justify scandals like the happiness of the wicked. Most such tragedies arise then simply from the encounter of different rationalities qua independent rationalities: say, the encounter of the physical laws that produce devastating earthquakes with the moral principles that lead us to attach value to human lives. There is no mystery to explain, just a tragedy to lament. The article thus captures the most important developments in political, social and economic thought of the Japanese eighteenth century through the concept of concurrent rationalities, following the thread of the treatments of the puzzle of the happy villains. (shrink)

In his correspondence, John Locke described his close friend Damaris Masham as ‘a determined foe to ecclesiastical tyranny’ and someone who had ‘the greatest aversion to all persecution on account of religious matters.’ In her short biography of Locke, Masham returned the compliment by commending Locke for convincing others that ‘Liberty of Conscience is the unquestionable Right of Mankind.’ These comments attest to Masham’s personal commitment to the cause of religious liberty. Thus far, however, there has been no scholarly discussion (...) of the tolerationist ethic underlying Masham’s 1705 publication, Occasional Thoughts. In this chapter, I argue that Masham’s work appeals to three common tolerationist principles of her time: the idea that the authorities should not use coercion and penalties as ways of imposing religious beliefs on others; the view that God requires human beings to attain salvation through their own efforts, and not by blindly following the dictates of the state-established religion; and the idea that the granting of liberty of conscience helps to ensure the peace and stability of political society. I show that Masham goes further than her tolerationist contemporaries by arguing that together these principles imply that a woman’s intellectual education—or the conscious cultivation of a woman’s ability to reflect critically on her religious beliefs—is vital for the good of the commonwealth. (shrink)

In this rich and detailed study of early modern women's thought, Jacqueline Broad explores the complexity of women's responses to Cartesian philosophy and its intellectual legacy in England and Europe. She examines the work of thinkers such as Mary Astell, Elisabeth of Bohemia, Margaret Cavendish, Anne Conway and Damaris Masham, who were active participants in the intellectual life of their time and were also the respected colleagues of philosophers such as Descartes, Leibniz and Locke. She also illuminates the continuities (...) between early modern women's thought and the anti-dualism of more recent feminist thinkers. The result is a more gender-balanced account of early modern thought than has hitherto been available. Broad's clear and accessible exploration of this still-unfamiliar area will have a strong appeal to both students and scholars in the history of philosophy, women's studies and the history of ideas. (shrink)

In his influential article ‘Essence and Modality’, Fine proposes a definition of necessity in terms of the primitive essentialist notion ‘true in virtue of the nature of’. Fine’s proposal is suggestive, but it admits of different interpretations, leaving it unsettled what the precise formulation of an Essentialist definition of necessity should be. In this paper, four different versions of the definition are discussed: a singular, a plural reading, and an existential variant of Fine’s original suggestion and an alternative version proposed (...) by Correia which is not based on Fine’s primitive essentialist notion. The first main point of the paper is that the singular reading is untenable. The second that given plausible background assumptions, the remaining three definitions are extensionally equivalent. The third is that, this equivalence notwithstanding, Essentialists should adopt Correia’s version of the definition, since both the existential variant, which has de facto been adopted as the standard version of the definition in the literature, and the plural reading suffer from problems connected to Fine’s primitive essentialist notion. (shrink)

Ian Hacking instigated a revolution in 20th century philosophy of science by putting experiments (“interventions”) at the top of a philosophical agenda that historically had focused nearly exclusively on representations (“theories”). In this paper, I focus on a set of conceptual tools Hacking (1992) put forward to understand how laboratory sciences become stable and to explain what such stability meant for the prospects of unity of science and kind discovery in experimental science. I first use Hacking’s tools to understand sources (...) of instability and disunity in rodent behavioral neuroscience. I then use them to understand recent grass-roots collaborative open science initiatives aimed at establishing stability in this research area and tease out some implications for unity of science and kind creation and discovery in cognitive neuroscience. -/- . (shrink)

Kaiho Seiry (1755-1817) is probably the first Japanese thinker to proclaim the contractual nature of human relationships. I examine in this paper the view of human beings that led him to this conclusion. Giving up previous definitions of humans, Seiry focuses on the faculty of practical reason. While this leads him to recognize a hierarchy of humans, some having more humanity than others, it also allows him to develop the most modern understanding of social relationship available in his time. His (...) radical reinterpretation of what it is to be a human being is all the more remarkable because it was done with the concepts and ideas provided by the Chinese Classics. Establishing new connections, giving new life to ideas that were never exploited, Seiry showed it was possible to make sense of modernity without using foreign concepts. (shrink)

Comment caractériser les utopies actuelles de la communication ? Le terme même d’utopie convient-il en ce domaine ? Pour répondre à ces questions, on se propose de retracer les thèmes fondamentaux des utopies d’autrefois, de Platon à Fourier , et de les confronter aux thèmes contemporains. La confrontation conduit à mettre en relief l’étendue des fausses similitudes.How to characterize the current utopias about communication ? Is the term itself – utopia – really appropriate ? To answer these questions, we propose (...) to review the fundamental themes of former utopias, from Plato to Fourier and to confront them to present themes. This comparison tends to clear the ambiguities of contemporary utopias and the extension of inadequate similarities. (shrink)

It is widely agreed that fiction is necessarily incomplete, but some recent work postulates the existence of universal fictions—stories according to which everything is true. Building such a story is supposedly straightforward: authors can either assert that everything is true in their story, define a complement function that does the assertoric work for them, or, most compellingly, write a story combining a contradiction with the principle of explosion. The case for universal fictions thus turns on the intuitive priority we assign (...) to the law of non-contradiction. My goal in this paper is to show that our critical and reflective literary practices set constraints on story-telling which preclude universal fictions. I will raise four stumbling blocks for universal fictionalists: the gap between saying and making true, our actual interpretive reactions to story-level contradictions, the criteria we accept for what counts as a story in our literary practices, and the undesirability of the universal fictionalist’s closure principles. (shrink)

La contribution de Michel Troper à la théorie générale du droit et à la théorie constitutionnelle est aujourd'hui reconnue et célébrée un peu partout dans le monde. Un talent d'architecte se tient à l'origine de cette audience rarement égalée dans la sphère francophone : celui qu'il faut pour accommoder toutes les exigences, quel que soit l'ordre de valeur dans lequel on les trouve : originalité, rigueur, souci de la fonction, esthétisme, solidité, adaptation, intelligence, inquiétude, esprit critique, renoncement, réalisme... A ces (...) mérites, on ajoutera une curiosité insatiable, un goût prononcé pour l'échange et le débat, un refus distingué de l'académisme, un sens exigeant de l'amitié et une méfiance profônde pour les adjectifs... C'est cet édifice de qualités que les élèves, collègues et amis de Michel Troper sont heureux de célébrer en lui offrant ces Mélanges. (shrink)

The premise that every work belongs to an art-kind has recently inspired a kind-centred approach to theories of art. Kind-centred analyses posit that we should abandon the project of giving a general theory of art and focus instead on giving theories of the arts. The main difficulty, however, is to explain what makes a given kind an art-kind in the first place. Kind-centred theorists have passed this buck on to appreciative practices, but this move proves unsatisfactory. I argue that the (...) root of this dissatisfaction stems not from the act of kicking the can down the road, but from not kicking it far enough. The missing ingredient, I argue, is a notion of convention which does the work of marking the difference between art and non-art for a given physical medium. (shrink)

Abstract: In this paper, I respond to James Sterba’s recent book ‘Is a Good God Logically Possible?’ I show that Sterba concludes that God is not logically possible by ignoring three important issues: (a) the different functions of leeway indeterminism (and the political freedom presupposed by it) and autonomy (the two are very different things, even though both go under the name of freedom), (b) the differences in the conditions of agency in God and in creatures, (there is non-parity in (...) how each must apply the single moral law), and (c) the non-parity between our knowledge and God’s. I provide a brief summary of Sterba’s arguments, and I develop the following points: 1. Sterba’s argument against a Free-Will Defense hinges on his conflation of political freedom and autonomy; 2. Sterba’s crucial premise for his argument against soul-making theodicies (namely, that the “Pauline Principle” should be applied univocally across God and creatures) is false; 3. Sterba’s arguments against skeptical theism depend on his assumption that our knowledge is comparable to that of God. In each case, Sterba either does not recognize non-parity between God and creatures or does not recognize the difference between the profane (e.g., political matters) and the sacred, (e.g., spiritual matters having to do with the inner nature of the soul’s development). (shrink)

A critic of utilitarianism, in a paper entitled “Innocence and Consequentialism” Laing argues that Singer cannot without contradicting himself reject baby farming (a thought experiment that involves mass-producing deliberately brain damaged children for live birth for the greater good of organ harvesting) and at the same time hold on to his “personism” a term coined by Jenny Teichman to describe his fluctuating (and Laing says, discriminatory) theory of human moral value. His explanation that baby farming undermines attitudes of care and (...) concern for the very young, can be applied to babies and the unborn (non-persons on his view) and contradicts positions that he adopts elsewhere in his work. (shrink)

Despite its centrality in the philosophy of cognitive science, there has been little prior philosophical work engaging with the notion of representation in contemporary NLP practice. This paper attempts to fill that lacuna: drawing on ideas from cognitive science, I introduce a framework for evaluating the representational claims made about components of neural NLP models, proposing three criteria with which to evaluate whether a component of a model represents a property and operationalising these criteria using probing classifiers, a popular analysis (...) technique in NLP (and deep learning more broadly). The project of operationalising a philosophically-informed notion of representation should be of interest to both philosophers of science and NLP practitioners. It affords philosophers a novel testing-ground for claims about the nature of representation, and helps NLPers organise the large literature on probing experiments, suggesting novel avenues for empirical research. (shrink)

As citizens, we hold certain truths to be self-evident: that the rights to own land, marry, inherit property, and especially to assume birthright citizenship should be guaranteed by the state. The laws promoting these rights appear not only to preserve our liberty but to guarantee society remains just. Yet considering how much violence and inequality results from these legal mandates, Jacqueline Stevens asks whether we might be making the wrong assumptions. Would a world without such laws be more just? (...) Arguing that the core laws of the nation-state are more about a fear of death than a desire for freedom, Jacqueline Stevens imagines a world in which birthright citizenship, family inheritance, state-sanctioned marriage, and private land ownership are eliminated. Would chaos be the result? Drawing on political theory and history and incorporating contemporary social and economic data, she brilliantly critiques our sentimental attachments to birthright citizenship, inheritance, and marriage and highlights their harmful outcomes, including war, global apartheid, destitution, family misery, and environmental damage. It might be hard to imagine countries without the rules of membership and ownership that have come to define them, but as Stevens shows, conjuring new ways of reconciling our laws with the condition of mortality reveals the flaws of our present institutions and inspires hope for moving beyond them. (shrink)

As citizens, we hold certain truths to be self-evident: that the rights to own land, marry, inherit property, and especially to assume birthright citizenship should be guaranteed by the state. The laws promoting these rights appear not only to preserve our liberty but to guarantee society remains just. Yet considering how much violence and inequality results from these legal mandates, Jacqueline Stevens asks whether we might be making the wrong assumptions. Would a world without such laws be more just? (...) Arguing that the core laws of the nation-state are more about a fear of death than a desire for freedom, Jacqueline Stevens imagines a world in which birthright citizenship, family inheritance, state-sanctioned marriage, and private land ownership are eliminated. Would chaos be the result? Drawing on political theory and history and incorporating contemporary social and economic data, she brilliantly critiques our sentimental attachments to birthright citizenship, inheritance, and marriage and highlights their harmful outcomes, including war, global apartheid, destitution, family misery, and environmental damage. It might be hard to imagine countries without the rules of membership and ownership that have come to define them, but as Stevens shows, conjuring new ways of reconciling our laws with the condition of mortality reveals the flaws of our present institutions and inspires hope for moving beyond them. (shrink)

In her Remarks Upon Some Writers (1743), Catharine Trotter Cockburn takes a seemingly radical stance by asserting that it is possible for atheists to be virtuous. In this paper, I examine whether or not Cockburn’s views concerning atheism commit her to a naturalistic ethics and a so-called radical enlightenment position on the independence of morality and religion. First, I examine her response to William Warburton’s critique of Pierre Bayle’s arguments concerning the possibility of a society of virtuous atheists. I argue (...) that this response shows Cockburn vacillating between a moral naturalism, on the one hand, and a theistic morality, on the other. Second, I draw on Cockburn’s letters to her niece Ann Arbuthnot, and her opinions concerning mystical ideas about “the will of God” in north-east Scotland in the mid-eighteenth century. I maintain that these letters give us a fuller appreciation of Cockburn’s naturalistic position. My conclusion is that Cockburn’s ideas concerning atheism prompt us to consider the close interplay between secular and religious principles in so-called radical ideas of the period. (shrink)

This anthology offers a comprehensive introduction to Pliny the Younger's Epistulae for intermediate and advanced Latin students, with the grammatical, lexical, and historical support to enable them to read quickly and fluidly. As the only selection of the letters with extensive commentary, it provides instructors with a unique and complete resource for students.ABOUT THE SERIESThe Oxford Greek and Latin College Commentaries is designed for students in intermediate or advanced Greek or Latin. Each volume includes a comprehensive introduction. The placement, on (...) the same page, of the ancient text, a running vocabulary, and succinct notes focusing on grammar, syntax, and distinctive features of style provides students with essential learning aids.Series Editors: Barbara Weiden Boyd, Bowdoin College, Stephen Esposito, Boston University, and Mary Lefkowitz, Wellesley CollegeAlso Available Ovid: Ars Amatoria, Book 3, Christopher M. Brunelle, St. Olaf CollegeForthcoming Latin VolumesSuetonius's Life of AugustusDarryl Phillips, Connecticut CollegeLucan's De Bello Civile, Book 5Jonathan Tracy, Massey University, New Zealand. (shrink)