The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO) project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to (...) existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI) and Phenotype Attribute and Trait Ontology (PATO) without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology) and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT)). The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource providing details on the people, policies, and issues being addressed in association with OBI. (shrink)

Victor and Cullen (1988) identified several dimensions of ethical climate that exist in organizations and organizational subunits. We tested the relationship between these dimensions of ethical climate and ethical behavior at different levels of analysis. Using Within and Between Analysis (WABA) (cf. Dansereau, Alutto and Yammarino, 1984), partial support was found for a relationship between dimensions of ethical climate and ethical behavior.

Posterior parietal cortex has traditionally been considered to be a sensory association area in which higher-order processing and intermodal integration of incoming sensory information occurs. In this paper, evidence from clinical reports and from lesion and behavioral-electrophysiological experiments using monkeys is reviewed and discussed in relation to the overall functional organization of posterior parietal association cortex, and particularly with respect to a proposed posterior parietal mechanism concerned with the initiation and control of certain classes of eye and limb movements. Preliminary (...) data from studies of the effects of posterior parietal lesions on oculomotor control in monkeys are reported.The behavioral effects of lesions of posterior parietal cortex in monkeys have been found to be similar to those which follow analogous damage of the minor hemisphere in humans, while behavioral-electrophysiological experiments have disclosed classes of neurons in this area which have functional properties closely related to the behavioral acts that are disrupted by lesions of the area. On the basis of current data from these areas of study, it is proposed that the sensory association model of posterior parietal function is inadequate to account for the complexities of the present evidence. Instead, it now appears that many diverse neural mechanisms are locatedin partin parietal cortex, that some of these mechanisms are involved in sensory processing and perceptual functions, but that others participate in motor control, and that still others are involved in attentional, motivational, or emotional processes. It is further proposed that the elementary units of these various neural mechanisms are distributed within posterior parietal cortex according to the columnar hypothesis of Mountcastle. (shrink)

The evolutionary advantage of psychological phenomena can be gleaned by comparing them with physical traits that have proven adaptive in other organisms. The present article provides a novel evolutionary explanation of suicide in humans by comparing it with aposematism in insects. Aposematic insects are brightly colored, making them conspicuous to predators. However, such insects are equipped with toxins that cause a noxious reaction when eaten. Thus, the death of a few insects conditions predators to avoid other insects of similar coloration. (...) Analogously, human suicides may increase the credibility of future suicide threats and attempts from others, conveying an evolutionary advantage to the phenotypic expression of suicidal behavior in low-fitness contexts. (shrink)

Is “good” a family-resemblance concept? Wittgenstein holds it is, since cases of goodness may not have anything in common, but there may be a continuous transition from some cases to others. Von Wright and Hacker argue it is not. They hold that family-resemblance concepts satisfy two conditions that goodness does not satisfy. I assess their arguments and then present a constitutivist account of goodness that Wittgenstein seems to endorse. The constitutivist account is what one would expect if goodness was a (...) family-resemblance concept. Finally, I note that Wittgenstein's nod towards non-descriptivism in the Investigations is paralleled by Stevenson's ethical emotivism. (shrink)

From the acclaimed author and scholar James C. Scott, the compelling tale of Asian peoples who until recently have stemmed the vast tide of state-making to live at arm’s length from any organized state society For two thousand years the disparate groups that now reside in Zomia (a mountainous region the size of Europe that consists of portions of seven Asian countries) have fled the projects of the organized state societies that surround them—slavery, conscription, taxes, corvée labor, epidemics, and (...) warfare. This book, essentially an “anarchist history,” is the first-ever examination of the huge literature on state-making whose author evaluates why people would deliberately and reactively remain stateless. Among the strategies employed by the people of Zomia to remain stateless are physical dispersion in rugged terrain; agricultural practices that enhance mobility; pliable ethnic identities; devotion to prophetic, millenarian leaders; and maintenance of a largely oral culture that allows them to reinvent their histories and genealogies as they move between and around states. In accessible language, James Scott, recognized worldwide as an eminent authority in Southeast Asian, peasant, and agrarian studies, tells the story of the peoples of Zomia and their unlikely odyssey in search of self-determination. He redefines our views on Asian politics, history, demographics, and even our fundamental ideas about what constitutes civilization, and challenges us with a radically different approach to history that presents events from the perspective of stateless peoples and redefines state-making as a form of “internal colonialism.” This new perspective requires a radical reevaluation of the civilizational narratives of the lowland states. Scott’s work on Zomia represents a new way to think of area studies that will be applicable to other runaway, fugitive, and marooned communities, be they Gypsies, Cossacks, tribes fleeing slave raiders, Marsh Arabs, or San-Bushmen. (shrink)

Ludwig Wittgenstein's _Tractatus Logico-Philosophicus_ and _Philosophical Investigations_ are among the most influential philosophical books of the twentieth century, and also among the most perplexing. Wittgenstein warned again and again that he was not and would not be understood. Moreover, Wittgenstein's work seems to have little relevance to the way philosophy is done today. In _Wittgenstein in Exile_, James Klagge proposes a new way of looking at Wittgenstein -- as an exile -- that helps make sense of this. Wittgenstein's exile (...) was not, despite his wanderings from Vienna to Cambridge to Norway to Ireland, strictly geographical; rather, Klagge argues, Wittgenstein was never at home in the twentieth century. He was in exile from an earlier era -- Oswald Spengler's culture of the early nineteenth century. Klagge draws on the full range of evidence, including Wittgenstein's published work, the complete Nachlaß, correspondence, lectures, and conversations. He places Wittgenstein's work in a broad context, along a trajectory of thought that includes Job, Goethe, and Dostoyevsky. Yet Klagge also writes from an analytic philosophical perspective, discussing such topics as essentialism, private experience, relativism, causation, and eliminativism. Once we see Wittgenstein's exile, Klagge argues, we will gain a better appreciation of the difficulty of understanding Wittgenstein and his work. (shrink)

In the process of challenging epistemological assumptions that preclude relationships between knowers and the objects of knowing, feminist epistemologists Lorraine Code and Donna Haraway also can be interpreted as troubling forms of argumentation predicated on positivist-derived logic. Against the latter, Christopher Tindale promotes a rhetorical model of argument that appears able to better engage epistemologies of situated knowledges. I detail key features of the latter from Code, especially, and compare and contrast them with relevant parts of Tindale’s discussion of context (...) on the rhetorical model, and I suggest ways that his work could be expanded to accommodate rhetorical implications of situated knowledges. (shrink)

In this book, he also demonstrates a skill shared by the greatest radical thinkers: to reveal positions we've been taught to think of as extremism to be emanations of simple human decency and common sense.

it is easy to think that he did. Clifford certainly had one. In a celebrated essay he argued for the thesis that “it is wrong always, everywhere and for anyone to believe anything upon insufficient evidence“; and his title was “The Ethics of Belief.” Clifford was not alone, for Huxley, also, was of that same opinion. For him, such belief was not just wrong: it was “the lowest depth of immorality.” With that opinion, and with those advocates of it, (...) class='Hi'>James was locked in a struggle throughout his life; and it is a reasonable suspicion that the opponent of one ethics of belief is himself an ethicist with a rival ethics of belief of his own. That suspicion, moreover, appears to be confirmed by James's best known essay. He himself came to the view that his The Will to Believe would have been better named The Right to Believe, and it is a commonplace that “right” is a word of the ethical vocabulary. In short, there are obvious signs pointing to a positive answer to our question. (shrink)

Pharmacy Benefit Managers (PBM) induce drug manufacturers to offer rebates to insurers and employers by denying coverage through formulary exclusions, impeding physician prescription through prior authorization, and reducing patient drug use through cost sharing. As they tighten these access obstacles, PBMs reduce the net prices received by the manufacturers.

The purpose of this study was to determine whether the ethical climate dimensions identified by Victor and Cullen (1987, 1988) could be replicated in the subunits of a multi-unit organization and if so, were the dimensions associated with particular types of operating units. We identified three of the dimensions of ethical climate found by Victor and Cullen and also found a new dimension of ethical climate related to service. Partial support was found for Victor and Cullen's hypothesis that certain ethical (...) climate dimensions are associated with particular forms of organizational governance and control. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:James's Faith-Ladder JAMES C. S. WERNHAM JAMES WROTE OFTEN of a "faith-ladder."' What he said about it has drawn some side-glances from critics, but not yet any sustained and careful look.' That is surprising, for what he says is puzzling enough to invite inquiry. It is also important enough to deserve it. His presentations of the ladder show significant variation, so it is useful to look (...) at a generous sample. In the interest of brevity the following six passages have been extracted from contexts which sometimes have an important bearing on them. The unquoted contexts will get attention as needed. 1. "The inner process is a succession of 'synthetic judgments'. What is so good, may be, ought to be, must be, shall be,--so far as I am concerned, I won't admit the opposite. ''s 2. "[W]e have a conception which being opposed by another is only probab /e. But we feel, it is so good that it isfit to be true, it ought to be true, it must be true etc. And then we say it shall be true for me, it/s true. ''4 3- "Its [faith's] natural logic is the Sorites: fit to be, ought to be, may be, must be, shall be, is etc.''5 4. "The following steps may be called the 'faith-ladder': ~. There is nothing absurd in a certain view of the world being true, nothing self-contradictory; ' To the best of my knowledge, the name "faith-ladder'"does not occur before 19o6. It occurs in "Faith and Reason" and in "Faith and the Right to Believe," both written in that year. But expositions of the thing predate the name. They are found as early as 1899, and in close connection with the will-to-believe doctrine. 9 Levinson's discussion is a partial exception. His treatment is more extended than most. See H. S. Levinson, $c/ence, Metaphysicsand the Chan~e of Salvation (Missoula, MT: Scholars Press, 1978), 161--67; also his The Religious Investigations of Wdliam James (Chapel Hill: University of North Carolina Press, 198 0, 231-34. s Letter to Baldwin, quoted in'R. B. Perry, The Thoughtand Characterof WilliamJames, 2 vols. (Boston: Little, Brown and Co., 1935), 2: 243. 4 Letter to Marshall, Feb. 9, 1899, quoted in Perry, Thought and Character,2: 24~. 5 William James, A Pluralistic Universe (Cambridge, MA and London: Harvard Universit~t Press, 1977), 199. [1o5] lO6 JOURNAL OF THE HISTORY OF PHILOSOPHY 28" 1 JANUARY I990 2. If might have been true under certain conditions; 3- It may be true even now; 4. It isfit to be true; 5- It ought to be true; 6. It must be true; 7- It s/m//be true, at any rate true for me. ''6 5. "Faith's form of argument is something like this: Considering a view of the world: 'It isfit to be true', she feels; 'it would be well if it were true; it might be true; it may be true; it ought to be true', she says; 'it must be true', she continues; 'it shall be true', she concludes, 'for me; that is, I will treat it as if it were true so far as my advocacy and actions are concerned'. ''7 6. "A conception of the world arises in you somehow, no matter how. Is it true or not? you ask. It might be true somewhere, you say, for it is not self-contradictory. It may be true, you continue, even here and now. It is fit to be true, it would be well if it were true, it ought to be true, you presently feel. It must be true, something persuasive in you whispers next; and then--as a final result--it shall be held for true, you decide; it shall be as if true, for you. ''s 9. Between these statements there are clear similarities and clear differences too. Some of them deserve to be noted, some to be noted and explored. a. In these accounts of it the ladder varies in the number of its rungs. By James's own count in one place, it has as many as seven. In... (shrink)

Integrated Information Theory (IIT) identifies consciousness with having a maximum amount of integrated information. But a thing’s having the maximum amount of anything cannot be intrinsic to it, for that depends on how that thing compares to certain other things. IIT’s consciousness, then, is not intrinsic. A mereological argument elaborates this consequence: IIT implies that one physical system can be conscious while a physical duplicate of it is not conscious. Thus, by a common and reasonable conception of intrinsicality, IIT’s consciousness (...) is not intrinsic. It is then argued that to avoid the implication that consciousness is not intrinsic, IIT must abandon its Exclusion Postulate, which prohibits overlapping conscious systems. Indeed, theories of consciousness that attribute consciousness to physical systems, should embrace the view that some conscious systems overlap. A discussion of the admittedly counterintuitive nature of this solution, along with some medical and neuroscientific realities that would seem to support it, is included. (shrink)

In 1896 William James published an essay entitled The Will to Believe, in which he defended the legitimacy of religious faith against the attacks of such champions of scientific method as W.K. Clifford and Thomas Huxley. James's work quickly became one of the most important writings in the philosophy of religious belief. James Wernham analyses James's arguments, discusses his relation to Pascal and Renouvier, and considers the interpretations, and misinterpretations, of James's major critics. Wernham shows (...) convincingly that James was unaware of many destructive ambiguitities in his own doctrines and arguments, although clear and consistent in his view that our obligation to believe in theism is not a moral but a prudential obligation -- a foolish-not-to-believe doctrine, rather than a not-immoral-to-believe one. Wernham also shows that the doctrine is best read as affirming the wisdom of gambling that God exists, a notion which James failed to distinguish from believing and which, among other things, he explicitly identified with faith. James's pragmatism, a theory concerning the meaning of truth, is shown to be quite distinct from the doctrine of The Will to Believe. In concentrating on a careful analysis of this doctrine of the will-to-believe, Wernham not only makes a major contribution to understanding James's philosophy, but also clarifies issues in the philosophy of religion and in the analysis of belief and faith. (shrink)

In 1844 Marx held that labor alienation was wholly eliminable, primarily through the abolition of private property. Work in the context of private property was alienating because it was performed for wages and the production of exchange-value. With such purposes, work was experienced as selfish and forced. With the abolition of private property, work would be performed for the production of use-¥alue, to satisfy human needs. With this human purpose, work would be experienced as a free and fulfilling expression of (...) life. (shrink)

The paper examines how supervisory influence and cognitive moral development influence subordinates' ethical decision-making and ethical behavior. The proposed interactive effect these major variables have on subordinates' ethical considerations are examined with respect to: (1) before an ethical dilemma occurs, (2) when faced with an ethical dilemma, (3) during the decision process, and (4) after ethical or unethical behavior has been executed. Propositions are presented and implications for research and practice are discussed.

This article examines a model of formation within higher education that is committed to educationally based spiritual formation, desiring to see students formed as people who love God and neighbor, devoting their lives to redemptive labor in the world. Deeply influenced by the evolving relationship between the department, the institution, and the broader evangelical culture, the Christian Formation and Ministry department of Wheaton College seeks to equip students with the theological and theoretical foundation, the personal maturity of character and faith, (...) and the practical ministry skills necessary to lead and participate in the formational and caring mission of the church in the world. Wheaton College’s unique approach to teaching spiritual formation and soul care in both their undergraduate and graduate programs is examined through a historical context of the department, a liberal arts and learning-centered approach to education that includes biblical foundations, philosophical framework, pedagogy, and teaching curriculum and assessment. (shrink)

What could it mean to be religious in a world where religion no longer retains its former authority? Posing this question for his fellow Western intellectuals who inhabit just such a world, James C. Edwards investigates the loss of religion's traditional power in a culture characterized by what he calls "normal nihilism"—a situation in which one's commitment to a particular set of values is all one really has, and in which traditional religion is only a means of interpretation used (...) to preserve what one most cares about. Recognizing the important historical role of religion in making us the people we are, he seeks to establish a viable understanding of religion without traditional beliefs and within the context of contemporary skepticism. _The Plain Sense of Things_ is a book more interested in the power of religion that in its truth and in what happens to that power when the claims to truth slacken their grip. (shrink)

While the concept of work ethic has been discussed in the Arab context :35–49, 2009), the significant conceptual and methodological limitations of the existing work ethic and work value research elucidate the need for a more robust investigation of the multidimensional work ethic construct in the Arab context. Multidimensionality of the work ethic concept has gained considerable attention in recent years as researchers attempt to move away from the religiously labeled Islamic and Protestant work ethic conceptualizations. The current study examines (...) the Arab work ethic through the use of the multidimensional work ethic profile on a sample of future business leaders in the United Arab Emirates. A total of 484 business students completed an Arabic version of the MWEP short form. The results show that centrality of work and hard work are the highest scoring work ethics followed by self-reliance, wasted time, and leisure. There are significant differences in work ethic dimensions across gender and categories of family breadwinner. No significant differences in work ethic dimensions are observed across categories of nationality and work preference groups. The findings are discussed in relation to the unique insight they offer on the nature of work ethic in an Arab context. (shrink)

Professions are granted autonomy by society, to regulate their own affairs. In return for the economic benefits autonomy grants to professions, society expects professions to act in a socially responsible manner. This paper presents a game-theoretic analysis of the relationship between society and professions, which shows that the relationship is unstable in the face of opportunities for professions to renege on the social contract. It also shows how periodic controversies regarding the degree to which professionals act in the public interest (...) are expected to occur periodically, and how they are resolved. (shrink)

If Socrates were asked “Is Wittgenstein Still an Analytic Philosopher?” he would first want to know the definition of “analytic philosophy.” Hanjo Glock has done an excellent job trying to offer a family-resemblance account, that connects with the method and content of Wittgenstein’s work and its origins. I will look at some further factors—Wittgenstein’s aims and his impact. When we include these considerations, we are led to wonder whether Wittgenstein is still an analytic philosopher.

In 1896 William James published an essay entitled The Will to Believe, in which he defended the legitimacy of religious faith against the attacks of such champions of scientific method as W.K. Clifford and Thomas Huxley. James's work quickly became one of the most important writings in the philosophy of religious belief. James Wernham analyses James's arguments, discusses his relation to Pascal and Renouvier, and considers the interpretations, and misinterpretations, of James's major critics. Wernham shows (...) convincingly that James was unaware of many destructive ambiguitities in his own doctrines and arguments, although clear and consistent in his view that our obligation to believe in theism is not a moral but a prudential obligation -- a foolish-not-to-believe doctrine, rather than a not-immoral-to-believe one. Wernham also shows that the doctrine is best read as affirming the wisdom of gambling that God exists, a notion which James failed to distinguish from believing and which, among other things, he explicitly identified with faith. James's pragmatism, a theory concerning the meaning of truth, is shown to be quite distinct from the doctrine of The Will to Believe. In concentrating on a careful analysis of this doctrine of the will-to-believe, Wernham not only makes a major contribution to understanding James's philosophy, but also clarifies issues in the philosophy of religion and in the analysis of belief and faith. (shrink)

In an attempt to learn from COVID-19, this essay features six responses to the question: what did COVID-19 teach us, expose in us, or purge out of us when it comes to spiritual formation in Christ? Each response was written independently of the others by one of the coauthors. Diane J. Chandler focuses in on how COVID-19 exposed grievous inequities for ethnic groups in the American church and broader society. Kelly M. Kapic reminds us of the goodness of human finitude (...) and how COVID restrictions have forced many of us to embrace our limitations. Siang-Yang Tan reflects on eight lessons he has learned during this pandemic year in his role shepherding a local church. James C. Wilhoit calls us to consider the structures that are needed for local church leadership to make wise and godly decisions in times of crisis. Richard Peace draws our attention to what might be learned from the forced monasticism brought about by COVID-19 quarantines. Finally, Ruth Haley Barton pauses to consider the interdependence of human life that has been dramatically illustrated by this pandemic. While these six responses certainly do not exhaust all there is for the church to learn from COVID, we present them in the spirit of “O Lord, teach us what we do not see” and hope they will inspire your own reflections. (shrink)

This article is an attempt to expound and distinguish\nbrentano's concept of "Intentional inexistence" (found in\n'psychologie von einem empirischen standpunkt') and\nhusserl's early concept of intentionality (in 'logische\nuntersuchungen'). The main purpose is to show that\nhusserl's phenomenological views are very different from\nand far more developed than brentano's and that he rejects\nmany of his concepts and doctrines. First, brentano's\ndesignation of eight defining characteristics of mental\nphenomena, the purpose of which is to define psychology, is\noutlined. This is followed by a detailed discussion of\nhusserl's criticisms and revisions, (...) emphasizing what\nhusserl thought was brentano's most important insight,\ni.E., That consciousness is intentional. A discussion of\nthree views of the nature of consciousness is given,\nconcluding with husserl's general criticisms that brentano\nfell victim to dualism and representationalism and that his\nconcept of the intentional nature of mind was distorted by\na commitment to naturalism, the latter being overcome only\nby husserl's own transcendental phenomenology in 'ideen'\nand later works. (shrink)

Wittgenstein’s Tractatus is one of the most important philosophical works of the Twentieth Century, yet it is brief and offers little orientation for the reader. This causes two problems: The first-time reader is left wondering what it could be about, and often leaves off reading in frustration after a few pages. The scholar is left with little guidance for interpretation. This paper recounts selected material from my book Tractatus in Context. While the book includes familiar material from Wittgenstein’s notebooks and (...) letters, it also includes lesser-known material such as untranslated correspondence and notebook entries, later lectures and dictations, notes from Ramsey, and previously unknown reviews. Some of the topics to be examined are: simple objects, atomic facts and elementary propositions, limits and boundaries, superstition, the shape of the visual field, and the role of the will. Given the occasion, I’ll also focus on some ways in which conversations with the Vienna Circle help illuminate obscure passages in the Tractatus. (shrink)

In recent years, theoretical and empirical developments in the area of organizational climate has provided the impetus for research concerning ethical climate. According to this latter research, ethical climate is a multi-dimensional construct which is manifested in organizations. Studies, however, have not focused on the relationship between ethical climate and ethical behavior. Furthermore, an enhanced understanding of the multi-dimensionality of ethical climate will likely advance what we know about organizational climate and culture in general. We propose further examination of ethical (...) climate by: (1) showing the conceptual relationship between ethical climate and ethical (or unethical) behavior in organizations; and (2) examining supervision as one of the principle influences on ethical climate and concomitant subordinate behavior. Finally, we explore the implications for future research on ethical climate. (shrink)

A timely and accessible synthesis of the strengths, weaknesses and reality of science through the eyes of a practicing scientist.