The Continuous Parameter Estimation Model is applied to develop individual genomic-level heritabilities for the latent hierarchical structure and developmental dynamics of Life History (LH) strategy LH strategies relate to the allocations of bioenergetic resources into different domains of fitness. LH has moderate to high population-level heritability in humans, both at the level of the high-order Super-K Factor and the lower-order factors, the K-Factor, Covitality Factor, and General Factor of Personality (GFP). Several important questions remain unexplored. We developed measures of (...) genome-level heritabilities employing an American sample of 316 monozygotic (MZ) and 274 dizygotic (DZ) twin dyads and a Swedish sample of 863 MZ and 475 DZ twin dyads. This novel heritability index measures individual genetic transmissibility, therefore opening new avenues for analyzing complex interactions among heritable traits inaccessible to standard structural equations methods. For these samples: (1) moderate to high heritability of factor loadings of Super-K on its lower-order factors is demonstrated, evidencing biological preparedness, genetic accommodation, and the gene-culture coevolution of biased epigenetic rules of development; (2) moderate to high heritability of the magnitudes of the effect of the higher-order factors upon their loadings on their constituent factors, evidencing genetic constraints upon phenotypic plasticity; and (3) that heritability of the LH factors, of factor loadings, and of the magnitudes of the correlations among factors are weaker among those with slower LH speeds, demonstrating that inter-individual variation in transmissibility is a function of individual socioecological selection pressures. (shrink)

Genetic engineering is still considered morally wrong by a large proportion of the public. Yet many scientists are puzzled about the public concern over a technology that, in their view, promises great benefits to humans and does not seem to cause more harm to animals than other practices which are rarely questioned. In this book, Michael Hauskeller takes public fears seriously and offers the idea of 'biological integrity' as a clarifying principle which can then be analyzed to show that (...) seemingly irrational public concerns about genetic engineering are not so irrational and that a philosophically sound justification of those concerns can indeed be given. (shrink)

This discussion note aims to address the two points which Lizza raises regarding my critique of his paper “Defining Death: Beyond Biology,” namely that I mistakenly attribute a Lockean view to his ‘higher brain death’ position and that, with respect to the ‘brain death’ controversy, both the notions of the organism as a whole and somatic integration are unclear and vague. First, it is known from the writings of constitutionalist scholars that the constitution view of human persons, a theory which (...) Lizza also holds, has its roots in John Locke’s thought. Second, contrary to Lizza’s claims, the notions of the organism as a whole and somatic integration are both more than adequately described in the biomedical and biophilosophical literature. (shrink)

In the chapter about the religion of art Hegel differentiates between four ways of integrating the Absolute: 1. integration though statues of gods, 2. integration through language, 3. integration through a religious cult, mysteries and festivities, 4. integration through the higher language of tragedy. Integration is conducted by the artist – the spirit is an artist. Still, it was demonstrated that these attempts of integration fail. Only one using speculative philosophy can succeed where the artist cannot: unity with the Absolute. (...) Integration, which was presented by Hegel in the Phenomenology of Spirit, and translated through different forms of the religion of art and the appropriation of the Absolute, leads to a point where the Absolute vanishes: at first the man uses it as a “cleaner, a house and in the feast of its victim“. Then, the inner being of the Absolute is consummated “in the mystery of bread of wine” and, finally, annihilated in the laughter of a comedy. The artist, an integrator of the Absolute in the life of the people, is at last so successful that the relationship is reversed: it is, finally, the true selfness, which rises as the master over the Absolute. The integration of the Absolute fails due to the hypocrisy of the artist’s work. The road the artist walks on, prepares the ground for uncovering an obvious religion and, thus, indirectly, for an appearance of speculative philosophy. (shrink)

This essay outlines a new preface for ethics demanded by the massive developments of the global age. It does so in and through the comparative use of "myths" to explicate the lived structure of experience. The essay begins by isolating main features of global dynamics, including proximity, the compression of the world and the expansion of consciousness, and also global, cultural reflexivity. In the second step of the "preface," it is argued that globality itself is a moral space in which (...) peoples must orient their lives. It is a moral space defined by the massive extension of human power in the modern world. In light of the challenge that global dynamics and the extension of human power now pose, the essay then isolates, methodologically, options for developing a global ethics, and advocates a distinctly hermeneutical approach. This approach is practiced in the last section of the "preface" by engaging ethically the biblical "myth" of creation and its reinterpretation in an epitome of Jesus's Torah teaching. The intention is to show how current religious thought can speak to massive challenges in a distinctive way. It is, again, to offer a preface to ethics. (shrink)

Much is being written these days about integration, its desirability and even its necessity when complex research problems are to be addressed. Seldom, however, do we hear much about the failure of such efforts. Because integration is an ongoing activity rather than a final achievement, and because today’s literature about integration consists mostly of manifesto statements rather than precise descriptions, an examination of unsuccessful integration could be illuminating to understand better how it works. This paper will examine the case of (...) prokaryote phylogeny and its apparent failure to achieve integration within broader tree-of-life accounts of evolutionary history. Despite the fact that integrated databases exist of molecules pertinent to the phylogenetic reconstruction of all lineages of life, and even though the same methods can be used to construct phylogenies wherever the organisms fall on the tree of life, prokaryote phylogeny remains at best only partly integrated within tree-of-life efforts. I will examine why integration does not occur, compare it with integrative practices in animal and other eukaryote phylogeny, and reflect on whether there might be different expectations of what integration should achieve. Finally, I will draw some general conclusions about integration and its function as a ‘meta-heuristic’ in the normative commitments guiding scientific practice. (shrink)

Cellular circadian clocks represent ancient anticipatory systems which co‐evolved with the first cells to safeguard their survival. Cyanobacteria represent one of the most ancient cells, having essentially invented photosynthesis together with redox‐based cellular circadian clocks some 2.7 billion years ago. Bioelectricity phenomena, based on redox homeostasis associated electron transfers in membranes and within protein complexes inserted in excitable membranes, play important roles, not only in the cellular circadian clocks and in anesthetics‐sensitive cellular sentience (awareness of environment), but also in the (...) coupling of single cells into tissues and organs of unitary multicellular organisms. This integration of cellular circadian clocks with cellular basis of sentience is an essential feature of the cognitive CBC‐Clock basis of cellular life. (shrink)

This essay will suggest that Gandhi’s true/real politics can be best understood in terms of the integrity of his ideas. This integrity refers to the fact that Gandhi was a man of integrity but more importantly to the fact that there was an integrity between his ideas and practice and between his ideas themselves. The continuities that we read in Gandhi—between politics and religion, politics religion and morality, the human being and nature and the past and (...) present—can best be unpacked if one were to understand this integrity. This essay will argue that one way to understand it would be to see that Gandhi’s arguments in economics, politics, religion, and even aesthetics drew from his fundamental moral convictions. Accordingly, the first part of this essay will suggest that Gandhi’s politics was premised on his integrity, i.e. on the idea that a human being ought to live an undivided life integrated around and by a commitment to his/her fundamental moral beliefs. The second part of the essay will argue then that a truly meaningful philosophical critique of Gandhi’s politics would only be one which could demonstrate how and where Gandhi’s politics failed to remain integrated with his fundamental moral convictions, i.e. which demonstrated how the integrity between Gandhi’s ideas themselves and between his ideas and practice broke so to say. In this context, the second section of the essay will bring in and philosophically examine Ajay Skaria’s, (Skaria, 2016) argument that satyagraha as a religion of the question (always seeking the truth which the satyagrahi did not know) involved the use of force and the imposition of the thekana/proper on the other. The essay will discuss this critique with a view to examine if it demonstrates that Gandhi’s practice disrupted his integrity both of his character and that between his ideas. (shrink)

In recent years, theories of social understanding have moved away from arguing that just one epistemic strategy, such as theory-based inference or simulation constitutes our ability of social understanding. Empirical observations speak against any monistic view and have given rise to pluralistic accounts arguing that humans rely on a large variety of epistemic strategies in social understanding. We agree with this promising pluralist approach, but highlight two open questions: what is the residual role of mindreading, i.e. the indirect attribution of (...) mental states to others within this framework, and how do different strategies of social understanding relate to each other? In a first step, we aim to clarify the arguments that might be considered in evaluating the role that epistemic strategies play in a pluralistic framework. On this basis, we argue that mindreading constitutes a core epiststrategy in human social life that opens new central spheres of social understanding. In a second step, we provide an account of the relation between different epistemic strategies which integrates and demarks the important role of mindreading for social understanding. (shrink)

Empirical bioethics is commonly understood as integrating empirical research with normative-ethical research in order to address an ethical issue. Methodological analyses in empirical bioethics mainly focus on the integration of socio-empirical sciences and normative ethics. But while there are numerous multidisciplinary research projects combining life sciences and normative ethics, there is few explicit methodological reflection on how to integrate both fields, or about the goals and rationales of such interdisciplinary cooperation. In this paper we will review some drivers for (...) the tendency of empirical bioethics methodologies to focus on the collaboration of normative ethics with particularly social sciences. Subsequently, we argue that the ends of empirical bioethics, not the empirical methods, are decisive for the question of which empirical disciplines can contribute to empirical bioethics in a meaningful way. Using already existing types of research integration as a springboard, five possible types of research which encompass life sciences and normative analysis will illustrate how such cooperation can be conceptualized from a methodological perspective within empirical bioethics. We will conclude with a reflection on the limitations and challenges of empirical bioethics research that integrates life sciences. (shrink)

In recent years, theories of social understanding have moved away from arguing that just one epistemic strategy, such as theory-based inference or simulation constitutes our ability of social understanding. Empirical observations speak against any monistic view and have given rise to pluralistic accounts arguing that humans rely on a large variety of epistemic strategies in social understanding. We agree with this promising pluralist approach, but highlight two open questions: what is the residual role of mindreading, i.e. the indirect attribution of (...) mental states to others within this framework, and how do different strategies of social understanding relate to each other? In a first step, we aim to clarify the arguments that might be considered in evaluating the role that epistemic strategies play in a pluralistic framework. On this basis, we argue that mindreading constitutes a core epiststrategy in human social life that opens new central spheres of social understanding. In a second step, we provide an account of the relation between different epistemic strategies which integrates and demarks the important role of mindreading for social understanding. (shrink)

THEOLOGICALLY CONSIDERED, THE VIRTUE OF PRUDENCE OR PRACTICAL wisdom disposes a moral agent to "reason rightly about things to be done" insofar as the acts of counsel, judgment, and command enable both the discernment and the embodiment of moral reality in the world created and redeemed by God in Jesus Christ. In that world, Christians live and act as both sinful and righteous, and they find their integrity and maturity in an ongoing practice of repentance, renewal, and perseverance.

Gallup surveys consistently show that nine in 10 Americans express a belief in God (Nash, Business, religion, and spirituality: A new synthesis, 2003 ), while more than 45 % claim to have some awareness of God on the job (Nash and McLellan, Church on Sunday, Work on Monday: The Challenges of Fusing Christian Values with Business Life, 2001 ). Recently, Lynn et al. (Journal of Business Ethics 85:227–243, 2009 ) argued that the ability to integrate the specific beliefs and (...) practices of one’s faith with the work one does represent an important although neglected area of research. As such, they developed and demonstrated convergent validity for the faith at work scale, designed to measure the extent to which individuals believe they are able to integrate their Judaeo-Christian beliefs and practices and their work. In a subsequent study, Lynn et al. (Human Relations 64:675–701, 2010 ) demonstrated that the faith at work scale was related to faith maturity, church attendance, age, and denominational strictness, and negatively associated with organizational size. No research, however, has examined the possible positive benefits of integrating faith and work. I therefore developed and tested hypotheses concerning the relationship between the faith at work scale and seven important life and work outcomes (satisfaction with life, intent to leave one’s job, self-rated job performance, job satisfaction, and three forms of organizational commitment). In all, four of seven hypotheses were confirmed. (shrink)

During the last decades the question of defining life has gained increased interest but, at the same time, the difficulty in reaching consensus on a possible answer has led many to skeptical positions. This, in turn, has raised a wider debate about why defining life is so hard and controversial. Such a debate introduces additional aspects to be considered, like the role and nature of a definition of life itself. In this paper, we will focus on those (...) aspects, arguing that progress can be made if we conceive definitions of life as open heuristic tools that contribute to develop specific research strategies in the biological sciences and, more generally, to increase our understanding of life’s complexity. In contrast with pragmatic or operationalist approaches, we will defend that definitions of life comprise a set of ontological assumptions, together with an inherent unifying vocation, so they should be subject to comparison and critical assessment, closely related to the success or failure of the corresponding research programs, but also to the success or failure in establishing well-grounded interconnections among the latter. We consider that the search for a more coherent, integrated and generalized theory of biology cannot be pursued without keeping an empirical standpoint, and the exercise of defining life should not be taken as an obstacle but as a valuable instrument to achieve that goal. (shrink)

The INBIOSA project brings together a group of experts across many disciplines who believe that science requires a revolutionary transformative step in order to address many of the vexing challenges presented by the world. It is INBIOSA’s purpose to enable the focused collaboration of an interdisciplinary community of original thinkers. This paper sets out the case for support for this effort. The focus of the transformative research program proposal is biology-centric. We admit that biology to date has been more fact-oriented (...) and less theoretical than physics. However, the key leverageable idea is that careful extension of the science of living systems can be more effectively applied to some of our most vexing modern problems than the prevailing scheme, derived from abstractions in physics. While these have some universal application and demonstrate computational advantages, they are not theoretically mandated for the living. A new set of mathematical abstractions derived from biology can now be similarly extended. This is made possible by leveraging new formal tools to understand abstraction and enable computability. [The latter has a much expanded meaning in our context from the one known and used in computer science and biology today, that is "by rote algorithmic means", since it is not known if a living system is computable in this sense (Mossio et al., 2009).] Two major challenges constitute the effort. The first challenge is to design an original general system of abstractions within the biological domain. The initial issue is descriptive leading to the explanatory. There has not yet been a serious formal examination of the abstractions of the biological domain. What is used today is an amalgam; much is inherited from physics (via the bridging abstractions of chemistry) and there are many new abstractions from advances in mathematics (incentivized by the need for more capable computational analyses). Interspersed are abstractions, concepts and underlying assumptions “native” to biology and distinct from the mechanical language of physics and computation as we know them. A pressing agenda should be to single out the most concrete and at the same time the most fundamental process-units in biology and to recruit them into the descriptive domain. Therefore, the first challenge is to build a coherent formal system of abstractions and operations that is truly native to living systems. Nothing will be thrown away, but many common methods will be philosophically recast, just as in physics relativity subsumed and reinterpreted Newtonian mechanics. -/- This step is required because we need a comprehensible, formal system to apply in many domains. Emphasis should be placed on the distinction between multi-perspective analysis and synthesis and on what could be the basic terms or tools needed. The second challenge is relatively simple: the actual application of this set of biology-centric ways and means to cross-disciplinary problems. In its early stages, this will seem to be a “new science”. This White Paper sets out the case of continuing support of Information and Communication Technology (ICT) for transformative research in biology and information processing centered on paradigm changes in the epistemological, ontological, mathematical and computational bases of the science of living systems. Today, curiously, living systems cannot be said to be anything more than dissipative structures organized internally by genetic information. There is not anything substantially different from abiotic systems other than the empirical nature of their robustness. We believe that there are other new and unique properties and patterns comprehensible at this bio-logical level. The report lays out a fundamental set of approaches to articulate these properties and patterns, and is composed as follows. -/- Sections 1 through 4 (preamble, introduction, motivation and major biomathematical problems) are incipient. Section 5 describes the issues affecting Integral Biomathics and Section 6 -- the aspects of the Grand Challenge we face with this project. Section 7 contemplates the effort to formalize a General Theory of Living Systems (GTLS) from what we have today. The goal is to have a formal system, equivalent to that which exists in the physics community. Here we define how to perceive the role of time in biology. Section 8 describes the initial efforts to apply this general theory of living systems in many domains, with special emphasis on crossdisciplinary problems and multiple domains spanning both “hard” and “soft” sciences. The expected result is a coherent collection of integrated mathematical techniques. Section 9 discusses the first two test cases, project proposals, of our approach. They are designed to demonstrate the ability of our approach to address “wicked problems” which span across physics, chemistry, biology, societies and societal dynamics. The solutions require integrated measurable results at multiple levels known as “grand challenges” to existing methods. Finally, Section 10 adheres to an appeal for action, advocating the necessity for further long-term support of the INBIOSA program. -/- The report is concluded with preliminary non-exclusive list of challenging research themes to address, as well as required administrative actions. The efforts described in the ten sections of this White Paper will proceed concurrently. Collectively, they describe a program that can be managed and measured as it progresses. (shrink)

This paper draws upon both Carl Jung’s theory of the psyche and nonviolence philosophy to re-examine curriculum dynamics in the context of teacher education. An integrative psychic life is enabled by the transcendent function of assimilating the unconscious to expand the horizon of consciousness while the integrative power of nonviolence heals the wounds of violence and promotes compassionate relationships. These theories follow different directions—the primary focus of Jung’s theory is the individual person and that of nonviolence theory is humane (...) relationality—but their underlying philosophical principles also intersect in ways that have important implications for today’s education. This paper focuses on three major intersections: the thread of interconnectedness is the undercurrent of an integrative psychic life and the underlying foundation for nonviolent relations; the shadow awareness within the individual psyche creates a social space for compassionate relationships with others; and complementary modes of psychic and nonviolent integration provide multiple pathways for teacher educators’ pedagogy and students’ self-education. After elaborating on these intersecting aspects and their curriculum implications, the final section discusses curriculum dynamics for subjective and social transformation through analysing the interactive relationships between and among teacher educators, students, texts, and contexts. (shrink)

Life education, also known as life and death education, is an important subject in Taiwan with institutions offering degree programs and courses that focus on quality learning and implementation of life education. What is interesting from the perspective of Taiwanese Education is that the teaching of life education also incorporates a number of Eastern-derived and conceptualized tenets, for example, Buddhist teaching and the importance of spiritual wisdom. This premise contends then that life education in Taiwan, (...) in general, is concerned with the promotion, fulfillment, and cherishing of quality life experiences (e.g., personal contentment, happiness). One example of life education, which resonates with other spiritual beliefs and religious faiths (e.g., Hinduism), is related to spiritual cultivation and the enlightenment of life wisdom. Our own teaching of the subject, likewise, places emphasis on the goal of teaching students to seek meaningful understanding of and appreciation for three major, interrelated components of life education: life wisdom, life practice, and life care. Life education is a beneficial subject as its theoretical understanding may help individuals cope with pathologies and negative life experiences. One negative life experience, in this case, is the ultimate fate of humankind: death. Approaching death and/or the onset of grief is something that we all have to experience. How does one approach death? It is not easy feat and, of course, grief for a loved one is personal and some of us struggle with this. We contend that spiritual cultivation and enlightenment, arising from life education, may assist us with the coping of death (e.g., the possibility of transcendence beyond the realm of life). Forming the premise of the present article, we propose that a person’s ‘spiritual and enlightened self’, reflecting the convergence of three major aspects of life education (i.e., Philosophical reflection, Enrichment of personal well-being, and Spiritual cultivation), would result in the initiation and creation of a number of virtues and positive characteristics – for example: having a positive outlook in life, showing compassion, forgiveness, etc. These virtues and quality characteristics, from our philosophical reasoning, are equivalent to those qualities that positive psychology advocates for. (shrink)

The somatic integration definition of life is familiar from the debate on the determination of death, with some bioethicists arguing that it supports brain death while others argue that some brain‐dead bodies exhibit sufficient somatic integration for biological life. I argue that on either interpretation, the somatic integration definition of life implies that neither the preimplantation embryo nor the postimplantation embryo meet the somatic integration threshold condition for organismal human life. The earliest point at which a (...) somatic integration determination of life could be made would be the beginning of the fetal stage, 9 weeks postfertilization. Bioethical implications are considered, specifically with respect to the moral status of the postimplantation embryo in embryo research and abortion. (shrink)

This paper argues that research on normative issues in the life sciences will benefit from a tighter integration of philosophy of science. We examine research on ethical, legal and social issues in the life sciences (“ELSI”) and discuss three illustrative examples of normative issues that arise in different areas of the life sciences. These examples show that important normative questions are highly dependent on epistemic issues which so far have not been addressed sufficiently in ELSI, RRI and (...) related areas of research. Accordingly, we argue for the integration of research on the epistemic aspects of the relevant areas of science into ELSI research to provide a better basis for addressing normative questions. (shrink)

Background Nurses providing care to patients with end-of-life or terminal illnesses often encounter ethically challenging situations leading to moral distress. However, existing quantitative studies have examined moral distress using instruments that address general clinical situations rather than those specific to end-of-life care. Furthermore, qualitative studies have often been limited to participants from a single unit or those experiencing moral distress-induced circumstances. A comprehensive and integrated understanding of the overarching process of moral distress is vital to discern the unique (...) circumstances surrounding end-of-life care and its consequential impacts. Research objectives To explore the moral distress experiences of nurses who are frequently involved in caring for patients with end-of-life or terminal illnesses and apply it to two existing theories: the model of moral distress and the ecological model. Research design A qualitative descriptive approach was employed. Participants and research context Seven focus group interviews involving 30 nurses were performed. The subsequent transcriptions underwent rigorous content analysis. Ethical considerations We obtained Institutional Review Board approval from a university. Focus group interviews were conducted with nurses who agreed to participate and signed the consent form. Findings The moral distress-inducing factors and nurses’ perceived impact of moral distress were identified and categorized based on moral distress theories and ecological models. A total of 15 categories and 30 subcategories across the following 4 domains were derived: (1) intrapersonal, (2) interpersonal, (3) organizational, and (4) structural factors. Conclusions End-of-life-specific circumstances induced moral distress among nurses, with both negative and positive impacts identified. Effective organizational and policy support is essential to manage conflicts, form a healthy organizational culture, provide training, and prevent unnecessary expenses due to the negative consequences of moral distress. (shrink)

This article analyses domestic and foreign reactions to a 2008 report in the British Medical Journal on the complementary and, as argued, synergistic relationship between palliative care and euthanasia in Belgium. The earliest initiators of palliative care in Belgium in the late 1970s held the view that access to proper palliative care was a precondition for euthanasia to be acceptable and that euthanasia and palliative care could, and should, develop together. Advocates of euthanasia including author Jan Bernheim, independent from but (...) together with British expatriates, were among the founders of what was probably the first palliative care service in Europe outside of the United Kingdom. In what has become known as the Belgian model of integral end-of-life care, euthanasia is an available option, also at the end of a palliative care pathway. This approach became the majority view among the wider Belgian public, palliative care workers, other health professionals, and legislators. The legal regulation of euthanasia in 2002 was preceded and followed by a considerable expansion of palliative care services. It is argued that this synergistic development was made possible by public confidence in the health care system and widespread progressive social attitudes that gave rise to a high level of community support for both palliative care and euthanasia. The Belgian model of so-called integral end-of-life care is continuing to evolve, with constant scrutiny of practice and improvements to procedures. It still exhibits several imperfections, for which some solutions are being developed. This article analyses this model by way of answers to a series of questions posed by Journal of Bioethical Inquiry consulting editor Michael Ashby to the Belgian authors. (shrink)

What gets integrated in integrative scientific practices has been a topic of much discussion. Traditional views focus on theories and explanations, with ideas of reduction and unification dominating the conversation. More recent ideas focus on disciplines, fields, or specialties; models, mechanisms, or methods; phenomena, problems. How integration works looks different on each of these views since the objects of integration are ontologically and epistemically various: statements, boundary conditions, practices, protocols, methods, variables, parameters, domains, laboratories, and questions all have their own (...) structures, functions and logics. I focus on one particular kind of scientific practice, integration of “approaches” in the context of a research system operating on a special kind of “platform.” Rather than trace a network of interactions among people, practices, and theoretical entities to be integrated, in this essay I focus on the work of a single investigator, David Wake. I describe Wake’s practice of integrative evolutionary biology and how his integration of approaches among biological specialties worked in tandem with his development of the salamanders as a model taxon, which he used as a platform to solve, re-work and update problems that would not have been solved so well by non-integrative approaches. The larger goal of the project to which this paper contributes is a counter-narrative to the story of 20th century life sciences as the rise and march of the model organisms and decline of natural history. (shrink)

To determine when the life of a human organism begins, Mark T. Brown has developed the somatic integration definition of life. Derived from diagnostic criteria for human death, Brown’s account requires the presence of a life‐regulation internal control system for an entity to be considered a living organism. According to Brown, the earliest point at which a developing human could satisfy this requirement is at the beginning of the fetal stage, and so the embryo is not regarded (...) as a living human organism. This, Brown claims, has significant bioethical implications for both abortion and embryo experimentation. Here, we dispute the cogency of Brown’s derivation. Diagnostic criteria for death are used to determine when an organism irreversibly ceases functioning as an integrated whole, and may vary significantly depending on how developed the organism is. Brown’s definition is derived from a specific definition of death applicable to postnatal human beings, which is insufficient for generating a general definition for human organismal life. We have also examined the bioethical implications of Brown’s view, and have concluded that they are not as significant as he believes. Whether the embryo is classified as a human organism is of peripheral interest—a far more morally relevant question is whether the embryo is a biological individual with an identity that is capable of persisting during development. (shrink)

The is the Editorial of the 2015 JPBMB Special Issue on Integral Biomathics: Life Sciences, Mathematics and Phenomenological Philosophy.

The article is devoted to the analysis of the anthropological views of Cyril of Turov on the rela­tionship of spiritual and bodily principles in human nature. In connection with this goal, a review of general anthropological ideas about human nature, presented in Eastern Christian patristic thought, is undertaken in order to identify possible continuity in the works of the ancient Russian author. The tradition of anthropological dualism characteristic of Byzantine patristic thought is shown. A detailed reflection of the relationship between (...) the spiritual and the carnal in human na­ture is considered on the material of such early works by Cyril of Turov as “A word about the monasticism”, “The Legend of the Chernorizsky rank”, and later – “The Parable of the Soul and Body”, “The Word about the Relaxed”. As a result of the research, the author of the article concludes that, firstly, physicality in the anthropology of the ancient Russian author acts as a ne­cessary outer shell for the soul, a form that is not sinful in isolation from spiritual movements, but acts as a receptacle of vice in connection with the free will of a person who has decided to live his life in satisfying earthly temptations and animals needs. Secondly, sin is an exclusively spiritual burden and spiritual responsibility. And, finally, thirdly, according to Cyril of Turov, soul and body are not opposed within a human being, but act as necessary, equally significant parts of the indivi­sible, undifferentiated integrity of the perfect creation of the Lord – man. (shrink)

We propose the camellia model for the integration of science and religion, in which each accepts the knowledge of the other, and they together build a flourishing bush of energetic, inquiring, life-directing, and truthful knowledge. The nature of happiness provides an example of how this model integrates scientific and religious knowledge.

In this chapter, Ayn Rand's new concept of morality is contrasted with familiar concepts according to which morality is an imposition on an individual that demands that he forgo his own interests as a sacrifice, whether to other people or to God. This chapter explores Rand's view that man's life is the standard of value and looks at each value that John Galt describes as supreme and ruling and, then, at the range of other values that Rand thinks man's (...) life. In discussing the supreme and ruling values, the chapter considers the three virtues that correspond to them: rationality, productiveness, and pride. It also looks at the four remaining virtues Rand identifies such as independence, integrity, honesty, and justice. Rand's conception of justice and the facts it recognizes is powerfully illustrated in Atlas Shrugged. Finally, the chapter examines Rand's view of heroism, which is closely connected with her ethics. (shrink)

Research in the globalization era has emphasized the importance of global competence and its integration into language teaching and learning. This article discussed the current focus of global education through the integration of global competence in English as a Second Language in Malaysia. The country’s global competence development among ESL teachers and students, along with its integration into English lessons, were identified, satisfying the need to achieve quality education. The global competence integration of ESL teachers will meet the fourth United (...) Nations Sustainable Development Goal, which strives for quality education. The global education goals form a critical starting point of this article, which articulates the connection to the targets in SDG 4. Hence, this article investigated the significance of global competence in language teaching and learning in Malaysia. Overall, the integration of global competence among ESL teachers can provide life-long learning, enhancing the quality of education. (shrink)

The majority of traditional students enrolled at most colleges and universities are a part of what has been termed the Millennial Generation, also known as Generation Y, which typically describes the group of individuals born in most of the 1980s and 1990s. This cohort’s life has been shaped by corporate scandals, economic instability, and worldwide tragedies. Concurrently, business ethics has become a popular topic in the news within the last 2 decades due to the increase in the number of (...) high-profile business scandals. Unfortunately, this trend has also been accompanied by an increased number of reported incidents of academic dishonesty at many major universities. Two underresearched factors that may be related to academic dishonesty and cheating behavior are religiosity and spirituality. This article attempts to shed more light on the relationship between religious beliefs and unethical behavior, with a focus on millennial college students. It is posited that religiosity and spirituality influence an individual’s attitudes, views, decisions, and ultimately behaviors. The results of this study indicate that religiosity but not spirituality is a predictor of students’ attitudes toward cheating and cheating behavior. (shrink)

Habermas absorb and integrate the achievements of contemporary philosophy of language, formed their own philosophy of language - in the form of pragmatics. This theory of speech acts by the meaning of the effectiveness of its intrinsic correlation between the demands of the analysis, pointed out the significance of speech acts only in the order presented in communicative action. Interpretation of speech acts in the ultimate source of the problem, Habermas introduces Husserl's "life-world" theory, and it was the transformation (...) of the form of pragmatics. Form pragmatics of life-world theory digestion of Husserl's life-world theory, a priori, while broadening the theory of Weber's rationalization of the behavior of sight. Habermas has absorbed and integrated many kinds of contemporary philosophy of language and constituted his own one, which is named formal linguistics. By analyzing the internal connection between the meaning of speech act and its validity claims, Habermas has emphasized that the meaning of speech act can be only demonstrated in communicative action. In the final analysis to the origin of meaning of speech act, he introduces Husserl's theory of lifeworld and reformulates it from the point of the formal linguistics. Habermas' theory of lifeworld removes the transcendental element existing in Husserl's theory , it enlarges Weber's theoretical horizon on rationalization of action at the same time. (shrink)

A philosophical exploration of the ideal of intellectual integrity drawing on Samuel Butler's semi-autobiographical Bildungsroaman, The Way of All Flesh; and relating this to C.S. Peirce's idea of the scientific attitude and Percy Bridgman's reflections on the conditions needed for this ideal to flourish.

Introduction. Cities play a key role in the development of countries and regions. The authors of the article emphasize the importance of the largest cities’ development, which is based on an industrial model that has not exhausted its potential. The authors show possibilities of urban development on the basis of the industrial sector effective functioning in order to improve the citizens’ welfare, meet their needs and improve the life quality. In this regard, the authors formulate a hypothesis that the (...) largest Russian cities developing according to the industrial model have and are able to realize their potential in order to improve the life quality, preserve and increase the population on their territory. The authors set a goal: to identify the possibilities for developing industrial-type megalopolises to improve the population’s life quality of the (PLQ). Methods. The authors use the following information base: strategic documents of different levels, statistical data, scientific literature, analytical documents, and expert assessments of the megalopolises’ development. The authors also use an industrial model for developing the largest cities; they determine conditions under which the potential of megacities can be realized to improve the citizens’ life quality and carry out an analysis of the demographic and social situation in the largest Russian industrial cities. The authors evaluate some approaches and theses of the study as exemplified by the following cities with a million-plus population: Yekaterinburg, Krasnoyarsk, Chelyabinsk, and Omsk and they group the cities according to the signs of growth and decline, which is illustrated by favorable or unfavorable demographic trends. To confirm the identified trends and problems of the largest cities, the authors provide the results of expert assessments on the population’s life quality and the state of the urban environment and emphasize the need for a systemic integrated development of the largest cities of industrial type to improve the life quality of the population of megalopolises. The scientific novelty of the study consists in substantiating the prospects for the socio-economic development of the largest industrial cities of Russia on the basis of an industrial model that provides for the technological transformation of the economy, the use of agglomeration effects, the formation of a friendly urban environment for residents and the achievement of socialization of urban space. Results and conclusions. As a result of the analysis and typology of the largest cities by functional specialization, two groups of cities were identified: one group with signs of demographic growth, the second with signs of decline. The cities of the first group have a greater economic potential, opportunities for agglomeration, provide more comfortable living and consolidation of the population on their territory. On the contrary, cities with signs of decreasing have fewer opportunities (resources), are less diversified, the urban environment in them is less comfortable, which is reflected in the citizens’ life quality and is accompanied by the population’s outflow. At the same time, it was revealed that all analyzed cities actively use digital technologies, realizing, in particular, the concept of a «smart city». At the same time, cities with signs of decreasing show high IQ indicators of cities. Taking into account the identified problems, the authors propose promising directions for the development of industrial megalopolises with signs of decline. (shrink)

The outbreak of the novel coronavirus pandemic, otherwise known as COVID-19 brought about the use of new terminologies—new lexical items such as social distancing, self-isolation, and lockdown. In developed countries, basic social amenities to support these are taken for granted; this is not the case in West African countries. Instead, those suggested safeguards against contracting COVID-19 have exposed the infrastructural deficit in West African countries. In addition, and more profoundly, these safeguards against the disease have distorted the traditional community-individuality balance. (...) The enforcement of social distancing, self-isolation, and lockdown has made it impossible for West Africans to drift to their ancestral homes and villages, as is usually the case in times of crisis, with attendant consequences for communal life and traditional burial rites. This could be one of the reasons why some COVID-19 patients are escaping from isolation centres, since to die in such centres violates their bodily integrity at an ontological level. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Hegel's Concept of Life: Self-Consciousness, Freedom, Logic by Karen NgMarina F. BykovaKaren Ng. Hegel's Concept of Life: Self-Consciousness, Freedom, Logic. Oxford: Oxford University Press, 2020. Pp. iii + 319. Hardback, $85.00.In her insightful book, Karen Ng defends the fundamental significance of Hegel's concept of life, which she considers "constitutive" not merely of his dynamic account of reason but also of his "idealist program" itself (3–4), (...) the very core structure that grounds his idealism (151, 291). Integrating this concept into his philosophy allows Hegel to resolve three systematic problems indicated in the subtitle of the book: self-consciousness, freedom or self-determination, and logical form.The book offers a systematic account of the logical concept of life by defending three interconnected claims, helpfully summarized in chapter 1. The first, rather general claim clarifies Ng's interpretive point of departure. She maintains that the "core tenets" of Hegel's philosophy can be understood through the "purposiveness theme" inherited from Kant's a priori principle of purposiveness in his Critique of Judgment (5, 43). Ng advances this claim in chapter 2, where she argues that it is working through Kant's concept of inner purposiveness of natural ends from the teleological power of judgment that leads Hegel to develop his own account of Concept, which is foundational for his entire philosophical system (61–64).Chapter 3 continues the examination of Hegel's immediate predecessors in relation to the interpretation of his "speculative identity thesis" (8), which constitutes the second claim. According to Ng, Hegel first introduces this thesis—which remains central to all his works—in the Differenzschift. In this work, Hegel, siding with Schelling, criticizes Fichte's subjective version of idealism, more specifically for his explanation of the relation between subject and object as constructed and facilitated by subjective consciousness itself, thus rendering "nature lifeless and dead" (88). Opposing this approach, in the Phenomenology of Spirit, Hegel interprets the identity of object and subject as facilitated by the relation and opposition between self-consciousness and life. Thus, the speculative identity thesis assumes a fundamental significance of life for self-consciousness. Unfolding this thesis is at the core of Hegel's absolute method in the Science of Logic as well. On Ng's reading, Hegel's speculative thesis along with his account of self-consciousness also have their roots in the purposiveness theme inherited from Kant. What is at work here is Kant's claim that the principle of purposiveness is a necessary condition for judgment, which Hegel develops into a claim about the concept of life as being constitutive for self-consciousness.In the rest of the book (chapters 4–8), devoted to a close analysis of Hegel's Science of Logic, Ng advances her third and perhaps most original claim: understanding Hegel's [End Page 527] Subjective Logic "as his own version of a 'critique of judgment'" (18). She demonstrates that this part of the Logic offers a positive account of the concept of life that Hegel develops in his critical interaction with Kant. The most illustrative in this respect is the "Subjectivity" section of the Logic, in which the form of life is presented as the ground and presupposition of Hegel's theory of concepts and judgments. According to Ng, such a reading makes evident that "life opens up the space of reasons" (234, 281).Chapter 4 takes up Hegel's immanent deduction of the Concept argument, revealing that the key to understanding it is the concept of reciprocity (Wechselwirkung) (127), most fully recognizable as an internal purposiveness of the Concept itself.Ng traces the purposiveness theme through the entirety of the Subjective Logic, establishing its significance for understanding the deduction of the Concept and for the transition to the Idea. In her analysis, she closely follows Hegel's division of the Subjective Logic and addresses Subjectivity, Objectivity, and the Idea in chapters 5–8, respectively. With chapter 5, Ng moves to a discussion of how Hegel finds judgment to arise from the "original judgement of life," the initial unity and division of subject and object within life (172). Chapter 6 extends this discussion by elucidating the tension Hegel... (shrink)

Substituted judgment assumes adequate knowledge of patient’s mind-set. However, surrogates’ prediction of individual healthcare decisions is often inadequate and may be based on shared background rather than patient-specific knowledge. It is not known whether surrogate’s prediction of patient’s integrative life-story narrative is better. Respondents in 90 family pairs rank-ordered 47 end-of-life statements as life-story narrative measure and completed instruments on decision-control preference and healthcare-outcomes acceptability as control measures, from respondent’s view and predicted pair’s view. They also scored (...) their confidence in surrogate’s decision-making and familiarity with pair’s healthcare-preferences. Life-story narratives’ prediction was examined by calculating correlation of statements’ ranking scores between respondent-personal and respondent-surrogate Q-sorts and between respondent-surrogate and pair-personal Q-sorts before and after controlling for correlation with respondent-personal scores, and by comparing percentages of respondent-surrogate Q-sorts co-loading with pair-personal vs. respondent-personal Q-sorts. Accuracy in predicting decision-control preference and healthcare-outcomes acceptability was determined by percent concordance. Results were compared among subgroups defined by intra-pair relationship, surrogate’s decision-making confidence, and healthcare-preferences familiarity. Mean age was 35.4 years, 69% were females, and 73 and 80% reported ≥ very good health and life-quality, respectively. Mean surrogate’s decision-making confidence score was 3.35 and 75% were ≥ familiar with pair’s healthcare-preferences. Mean projection, simulation, and adjusted-simulation correlations were 0.68, 0.42, and 0.26, respectively. Out of 180 respondent-surrogate Q-sorts, 24, 9, and 32% co-loaded with respondent-personal, pair-personal, or both Q-sorts, respectively. Accuracy in predicting decision-control preference and healthcare-outcomes acceptability was 47 and 52%, respectively. Surrogate’s decision-making confidence score correlated with adjusted-simulation’s correlation score. There were significant differences among the husband-wife, parent-child, and sibling-sibling subgroups in percentage of respondent-surrogate Q-sorts co-loading with pair-personal Q-sorts and percent agreement on healthcare-outcomes acceptability. Despite high self-reported surrogate’s decision-making confidence and healthcare-preferences familiarity, family surrogates are variably inadequate in simulating life-story narratives. Simulation accuracy may not follow the next-of-kin concept and is 38% based on shared background. (shrink)

In nearly all aspects of life, humans are crossing lines of no return. Modern science is leading us into vast uncharted territory—far beyond the invention of nuclear weapons or taking us to the moon.Today, in labs all over the world, scientists are performing experiments that threaten to fundamentally alter the practical character and ethical color of our everyday lives. In The End of Life as We Know It, bestselling author Michael Guillen takes a penetrating look at how the (...) scientific community is pushing the boundaries of morality, including: • Scientists who detached the head of a Russian man from his crippled, diseased body, and stitching it onto a healthy new donated body. • Fertility experiments aimed at allowing designer babies to be conceived with the DNA from three or more biological parents. • The unprecedented politicization of science – for example, in the global discussion about climate change that is pitting “deniers” against “alarmists” and inspiring Draconian legislation, censorship, and legal prosecutions. • The integration of Artificial Intelligence into communications and the economy. The End of Life as We Know It takes us into labratories and boardrooms where these troubling advances are taking place and asks the question no scientists seem to be asking: What does this mean for the future of humanity? (shrink)

Religion and the Philosophy of Life considers how religion as the source of civilization transforms the fundamental bio-sociology of humans through language and the somatic exploration of religious ritual and prayer. Gavin Flood offers an integrative account of the nature of the human, based on what contemporary scientists tell us, especially evolutionary science and social neuroscience, as well as through the history of civilizations. Part one contemplates fundamental questions and assumptions: what the current state of knowledge is concerning (...) class='Hi'>life itself; what the philosophical issues are in that understanding; and how we can explain religion as the driving force of civilizations in the context of human development within an evolutionary perspective. It also addresses the question of the emergence of religion and presents a related study of sacrifice as fundamental to religions' views about life and its transformation. Part two offers a reading of religions in three civilizational blocks-India, China, and Europe/the Middle East-particularly as they came to formation in the medieval period. It traces the history of how these civilizations have thematised the idea of life itself. Part three then takes up the idea of a life force in part three and traces the theme of the philosophy of life through to modern times. On the one hand, the book presents a narrative account of life itself through the history of civilizations, and on the other presents an explanation of that narrative in terms of life.". (shrink)

"All art should become science and all science art; poetry and philosophy should be made one." Friedrich Schlegel's words perfectly capture the project of the German Romantics, who believed that the aesthetic approaches of art and literature could reveal patterns and meaning in nature that couldn't be uncovered through rationalistic philosophy and science alone. In this wide-ranging work, Robert J. Richards shows how the Romantic conception of the world influenced (and was influenced by) both the lives of the people who (...) held it and the development of nineteenth-century science. Integrating Romantic literature, science, and philosophy with an intimate knowledge of the individuals involved—from Goethe and the brothers Schlegel to Humboldt and Friedrich and Caroline Schelling—Richards demonstrates how their tempestuous lives shaped their ideas as profoundly as their intellectual and cultural heritage. He focuses especially on how Romantic concepts of the self, as well as aesthetic and moral considerations—all tempered by personal relationships—altered scientific representations of nature. Although historians have long considered Romanticism at best a minor tributary to scientific thought, Richards moves it to the center of the main currents of nineteenth-century biology, culminating in the conception of nature that underlies Darwin's evolutionary theory. Uniting the personal and poetic aspects of philosophy and science in a way that the German Romantics themselves would have honored, The Romantic Conception of Life alters how we look at Romanticism and nineteenth-century biology. (shrink)

Learning is a central component of human life and essential for personal development. Therefore, utilizing new technologies in the learning context and exploring their combined potential are considered essential to support self-directed learning in a digital age. A learning environment can be expanded by various technical and content-related aspects. Gamification in the form of elements from video games offers a potential concept to support the learning process. This can be supplemented by technology-supported learning. While the use of tablets is (...) already widespread in the learning context, the integration of a social robot can provide new perspectives on the learning process. However, simply adding new technologies such as social robots or gamification to existing systems may not automatically result in a better learning environment. In the present study, game elements as well as a social robot were integrated separately and conjointly into a learning environment for basic Spanish skills, with a follow-up on retained knowledge. This allowed us to investigate the respective and combined effects of both expansions on motivation, engagement and learning effect. This approach should provide insights into the integration of both additions in an adult learning context. We found that the additions of game elements and the robot did not significantly improve learning, engagement or motivation. Based on these results and a literature review, we outline relevant factors for meaningful integration of gamification and social robots in learning environments in adult learning. (shrink)

In this peer commentary on L. Syd M. Johnson’s “Inference and Inductive Risk in Disorders of Consciousness,” I argue for the necessity of disability education as an integral component of decision-making processes concerning patients with DOC and, mutatis mutandis, all patients with disabilities. The sole qualification Johnson places on such decision-making is that stakeholders are educated about and “understand the uncertainties of diagnosis and prognosis.” Drawing upon research in philosophy of disability, social epistemology, and health psychology, I argue that this (...) educational qualification is insufficient to address systemic ableism and other forms of epistemic bias in quality of life judgments. (shrink)

In her introduction to this collection, Tymieniecka presents her phenomenology of life - the leitmotif of the three-volume anniversary publication of Analecta Husserliana - as something that stands out from preceding historical attempts to investigate life in an 'integral' or 'scientific' way. After an incubation lasting throughout the 2000 years of Occidental philosophy, this scientific phenomenology/philosophy of life at last uncovers the entire area of the 'inner workings of Nature', exposing the way in which the 'sufficient reason' (...) and the 'ground' of beingness as such crystallise out of the 'onto poietic' process. This onto-poietic process, continuing as it does in the human creative condition, also reveals the authentic genius of the works of the human spirit. This new and original philosophy, free of fallacious simplifications, speculations and reductionism, opens up a basic starting point for all philosophy. Life, 'the theme of our times', at last receives a profound philosophical treatment. (shrink)

International migration is an important issue for many high‐income countries and is accompanied by opportunities as well as challenges. South Asians are the largest minority ethnic group in the United Kingdom, and this diaspora is reflective of the growing diversity of British society. An empirical study was performed to ascertain the faith‐based values, beliefs, views and attitudes of participants in relation to their perception of issues pertaining to end‐of‐life care. Empirical observations from this study, as well as the extant (...) knowledge‐base from the literature, are used to support and contextualise our reflections against a socio‐legal backdrop. We argue for accommodation of faith‐based values of migrants at end‐of‐life within normative structures of receiving countries. We posit the ethically relevant principles of inclusiveness, integration and embedment, for an innovative bioethical framework as a vehicle for accommodating faith‐based values and needs of migrants at end‐of‐life. These tenets work conjunctively, as well as individually, in respect of individual care, enabling processes and procedures, and ultimately for formulating policy and strategy. (shrink)

The essays included here represent Fox Keller's attempts to integrate the insights of feminist theory with those of her contemporaries in the history and philosophy of science.