Results for 'Thomas Bl Kirkwood'

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  1.  24
    The free‐radical theory of ageing – older, wiser and still alive.Thomas Bl Kirkwood & Axel Kowald - 2012 - Bioessays 34 (8):692-700.
    The continuing viability of the free‐radical theory of ageing has been questioned following apparently incompatible recent results. We show by modelling positional effects of the generation and primary targets of reactive oxygen species that many of the apparently negative results are likely to be misleading. We conclude that there is instead a need to look more closely at the mechanisms by which free radicals contribute to age‐related dysfunction in living systems. There also needs to be deeper understanding of the dynamics (...)
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  2.  21
    Human senescence.Thomas B. L. Kirkwood - 1996 - Bioessays 18 (12):1009-1016.
    Human life expectancy has increased dramatically through improvements in public health, housing, nutrition and general living standards. Lifespan is now limited chiefly by intrinsic senescence and its associated frailty and diseases. Understanding the biological basis of the ageing process is a major scientific challenge that will require integration of molecular, cellular, genetic and physiological approaches. This article reviews progress that has been made to date, particularly with regard to the genetic contribution to senescence and longevity, and assesses the scale of (...)
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  3.  16
    P53 and Ageing: Too Much of a Good Thing?Thomas B. L. Kirkwood - 2002 - Bioessays 24 (7):577-579.
    A recent report by Tyner et al.1 suggests that p53 is bad for longevity. Heterozygotic mice carrying a p53 mutation that apparently enhances the stability of the wild‐type protein showed shorter lifespans and faster ageing while also developing fewer tumours. This fits with the idea that cellular ageing is the price paid for better protection against unlimited proliferation of cancer cells. But other work shows that there is a strong positive association between DNA repair‐mediated protection against cancer and ageing. So (...)
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  4.  39
    Evolution of the human menopause.Daryl P. Shanley & Thomas B. L. Kirkwood - 2001 - Bioessays 23 (3):282-287.
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  5.  5
    The Genetics of Old Age.Thomas B. L. Kirkwood - 2002 - In Justine Burley & John Harris (eds.), A Companion to Genethics. Wiley-Blackwell. pp. 43–50.
    The prelims comprise: Introduction Genetic Architecture of the Life Span Genetics of Longevity Genetics and the Future of Old Age Conclusion.
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  6.  14
    Book review: Becoming immortal: Combining cloning and stem‐cell therapy. [REVIEW]Thomas B. L. Kirkwood - 2004 - Bioessays 26 (1):106-107.
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  7.  24
    Increasing longevity: an important question, a dubious answer. The evolution of death: Why we are living longer. (2006). By Stanley Shostak. State University of New York Press, Albany 246 pp. ISBN: 07914694689. [REVIEW]Thomas B. L. Kirkwood - 2007 - Bioessays 29 (7):710-711.
  8.  16
    Mitochondria and ageing: winning and losing in the numbers game.João F. Passos, Thomas von Zglinicki & Thomas B. L. Kirkwood - 2007 - Bioessays 29 (9):908-917.
    Mitochondrial dysfunction has long been considered a key mechanism in the ageing process but surprisingly little attention has been paid to the impact of mitochondrial number or density within cells. Recent reports suggest a positive association between mitochondrial density, energy homeostasis and longevity. However, mitochondrial number also determines the number of sites generating reactive oxygen species (ROS) and we suggest that the links between mitochondrial density and ageing are more complex, potentially acting in both directions. The idea that increased density, (...)
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  9.  3
    Biology of ageing.Olivier Toussaint, José Remacle, Brian F. C. Clark, Efstathios S. Gonos, Claudio Franceschi & Thomas B. L. Kirkwood - 2000 - Bioessays 22 (10):954-956.
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  10.  5
    Even when no one is looking: fundamental questions of ethical education.Jan Hábl - 2018 - Eugene, Oregon: Cascade Books.
    This book is not a list or an overview of various theories of ethics. Nor is it a didactic manual for specific teaching units on moral education aimed at some group based on age or a particular theme (although some educational frameworks will be proposed). As the title suggests, the book intends to seek the starting points or foundations without which no moral education would be possible. The goal is to formulate and tackle the key questions that precede all moral (...)
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  11.  12
    Frances McSparran, ed., Octovian Imperator, ed. from MS BL Cotton Caligula A II. Heidelberg: Carl Winter, 1979. Paper. Pp. 123. DM 38. [REVIEW]Thomas J. Heffernan - 1981 - Speculum 56 (2):458.
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  12.  77
    Residuated lattices arising from equivalence relations on Boolean and Brouwerian algebras.Thomas Vetterlein - 2008 - Mathematical Logic Quarterly 54 (4):350-367.
    Logics designed to deal with vague statements typically allow algebraic semantics such that propositions are interpreted by elements of residuated lattices. The structure of these algebras is in general still unknown, and in the cases that a detailed description is available, to understand its significance for logics can be difficult. So the question seems interesting under which circumstances residuated lattices arise from simpler algebras in some natural way. A possible construction is described in this paper.Namely, we consider pairs consisting of (...)
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  13.  27
    A Way to Interpret Łukasiewicz Logic and Basic Logic.Thomas Vetterlein - 2008 - Studia Logica 90 (3):407-423.
    Fuzzy logics are in most cases based on an ad-hoc decision about the interpretation of the conjunction. If they are useful or not can typically be found out only by testing them with example data. Why we should use a specific fuzzy logic can in general not be made plausible. Since the difficulties arise from the use of additional, unmotivated structure with which the set of truth values is endowed, the only way to base fuzzy logics on firm ground is (...)
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  14.  28
    The Long‐term Unemployed: A New Protected Class of Employee?Thomas A. Hemphill, Waheeda Lillevik & Francine Cullari - 2012 - Business and Society Review 117 (4):535-553.
    Since the onset of the latest United States (U.S.) recession (beginning in December 2007), the U.S. economy has been posting high unemployment levels consistently exceeding 8 percent. Of specific interest, the U.S. Department of Labor, Bureau of Labor Statistics (BLS), reports on a specific subset of the U.S. unemployed: the long‐term unemployed, defined as those who are unemployed for 27 weeks and over. Since December 2009, the share of the long‐term unemployed of the total U.S. unemployed has exceeded 40 percent (...)
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  15.  16
    Shaping Knowledge about American Labor: External Advising at the U.S. Bureau of Labor Statistics in the Twentieth Century.Thomas A. Stapleford - 2010 - Science in Context 23 (2):187-220.
    ArgumentCreated in 1884, the U.S. Bureau of Labor Statistics has been the major federal source for data in the United States on labor-related topics such as prices, unemployment, compensation, productivity, and family expenditures. This essay traces the development and transformation of formal and informal consulting relationships between the BLS and external groups over the twentieth century. Though such a history cannot, of course, provide a comprehensive analysis of how political values have shaped the construction of labor statistics during this period, (...)
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  16.  40
    Domestic Religious Themes in Pompeian Painting Thomas Fröhlich: Lararien- und Fassadenbilder in den Vesuvstädten: Untersuchungen zur 'volkstümlichen' pompejanischen Malerei. (Mitteilungen des Deutschen Archäologischen Instituts. Römische Abteilung, Ergänzungsheft 32.) Pp. 370; 11 text-figs., 23 colour pls, 41 bl. and w. pls. Mainz: Von Zabern, 1991. DM 198. [REVIEW]Roger Ling - 1993 - The Classical Review 43 (01):139-141.
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  17.  17
    Thomas Scott of Canterbury (1566–1635): Patriot, civic radical, puritan.Cesare Cuttica - 2008 - History of European Ideas 34 (4):475-489.
    This article sheds new light on the interesting but little-studied figure of Thomas Scott of Canterbury (1566–1635). In presenting Scott's ideas I will modify the interpretation laid out by Peter Clark whose groundbreaking study, ‘Thomas Scott and the Growth of Urban Opposition to the Early Stuart Regime’, is still the only secondary source that pays detailed attention to Scott and his thought, especially his religious opinions. The necessity to revisit Clark's interpretation of Scott's place within the political and (...)
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  18.  13
    Laudatio.Timothy B. Noone - 2010 - Franciscan Studies 68 (1):259-264.
    In lieu of an abstract, here is a brief excerpt of the content:LaudatioTimothy B. Noone (bio)On Sunday, July 26, 2009, the Franciscan Institute was pleased to award to Dr. Girard J. Etzkorn its 22nd Franciscan Institute Medal in recognition of a lifetime of scholarship, editing and publication of texts on medieval philosophy and theology, with a special emphasis on the Franciscan intellectual tradition. The ceremony was held in the Trustees Room of Doyle Hall on the campus of St. Bonaventure University (...)
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  19.  45
    Moving_ Through the Literature: What Is the Emotion Often Denoted _Being Moved?.Janis H. Zickfeld, Thomas W. Schubert, Beate Seibt & Alan P. Fiske - 2019 - Emotion Review 11 (2):123-139.
    When do people say that they are moved, and does this experience constitute a unique emotion? We review theory and empirical research on being moved across psychology and philosophy. We examine feeling labels, elicitors, valence, bodily sensations, and motivations. We find that the English lexeme being moved typically (but not always) refers to a distinct and potent emotion that results in social bonding; often includes tears, piloerection, chills, or a warm feeling in the chest; and is often described as pleasurable, (...)
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  20.  65
    The impact of ethics code familiarity on manager behavior.Thomas R. Wotruba, Lawrence B. Chonko & Terry W. Loe - 2000 - Journal of Business Ethics 33 (1):59 - 69.
    Codes of ethics exist in many, if not the majority, of all large U.S. companies today. But how the impact of these written codes affect managerial attitudes and behavior is still not clearly documented or explained. This study takes a step in that direction by proposing that attention should shift from the codes themselves as the sources of ethical behavior to the persons whose behavior is the focus of these codes. In particular, this study investigates the role of code familiarity (...)
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  21.  42
    Business, Ethics, and Carol Gilligan's.Thomas I. White - 1992 - Business Ethics Quarterly 2 (1):51-61.
    This article argues that Carol Gilligan's research in moral development psychology, work which claims that women speak about ethics in a "different voice" than men do, is applicable to business ethics. This essay claims that Gilligan's "ethic of care" provides a plausible explanation for the results of two studies that found men and women handling ethical dilemmas in business differently. This paper also speculates briefly about the management implications of Gilligan's ideas.
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  22. Art and the Word of God (Arte e la Parola di Dio): A Study of Angelico Rinaldo Zarlenga, O.P. ed. by Vincent I. Zarlenga, O.P. [REVIEW]Benedict M. Ashley - 1994 - The Thomist 58 (1):164-166.
    In lieu of an abstract, here is a brief excerpt of the content:164 BOOK REVIEWS "was presented with wine in the name of the whole University." That evening, one of the feasters recalled that this was the man who had written the foremost theological defense of the Royal Supremacy: the following morning, when Gardiner asked for vessels and vestments to say Mass before proceeding on his way, they were refused him, as to an excommunicate or a schismatic. This incident is (...)
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  23. Kreisel, the continuum hypothesis and second order set theory.Thomas Weston - 1976 - Journal of Philosophical Logic 5 (2):281 - 298.
    The major point of contention among the philosophers and mathematicians who have written about the independence results for the continuum hypothesis (CH) and related questions in set theory has been the question of whether these results give reason to doubt that the independent statements have definite truth values. This paper concerns the views of G. Kreisel, who gives arguments based on second order logic that the CH does have a truth value. The view defended here is that although Kreisel's conclusion (...)
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  24. Social Learning Strategies in Networked Groups.Thomas N. Wisdom, Xianfeng Song & Robert L. Goldstone - 2013 - Cognitive Science 37 (8):1383-1425.
    When making decisions, humans can observe many kinds of information about others' activities, but their effects on performance are not well understood. We investigated social learning strategies using a simple problem-solving task in which participants search a complex space, and each can view and imitate others' solutions. Results showed that participants combined multiple sources of information to guide learning, including payoffs of peers' solutions, popularity of solution elements among peers, similarity of peers' solutions to their own, and relative payoffs from (...)
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  25.  18
    Transformative Philosophy: Socrates, Wittgenstein, and the Democratic Spirit of Philosophy.Thomas Wallgren - 2006 - Lexington Books.
    The cross-fruition between analytical philosophy and continental philosophical traditions has stimulated a wide-ranging debate about the role of philosophy and the use of argument and reason in culture. Through a discussion of salient themes in the analytical tradition, in the work of the later Wittgenstein, and in critical theory,Transformative Philosophy articulates a novel conception of philosophy as a transformative care for self and others.
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  26.  49
    Preferences and reasons for communicating probabilistic information in verbal or numerical terms.Thomas S. Wallsten, David V. Budescu, Rami Zwick & Steven M. Kemp - 1993 - Bulletin of the Psychonomic Society 31 (2):135-138.
  27.  36
    From Foreground to Background: How Task-Neutral Context Influences Contextual Cueing of Visual Search.Xuelian Zang, Thomas Geyer, Leonardo Assumpção, Hermann J. Müller & Zhuanghua Shi - 2016 - Frontiers in Psychology 7.
  28.  30
    7 Reason and the practice of science.Thomas E. Wartenberg - 1992 - In Paul Guyer (ed.), The Cambridge companion to Kant. New York: Cambridge University Press. pp. 3--228.
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  29.  16
    The American Dependency Conflict: Continuities and Discontinuities in Behavior and Values of Countercultural Parents and Their Children.Thomas S. Weisner - 2001 - Ethos: Journal of the Society for Psychological Anthropology 29 (3):271-295.
  30.  55
    Anselm: Basic Writings.Thomas Williams - 1997 - Hackett.
    Ranging from his early treatises, the ’Monologion’ (a work written to show his monks how to meditate on the divine essence) and the ’Proslogion’ (best known for its advancement of the so-called ontological argument for the existence of God), to his three philosophical dialogues on metaphysical topics such as the relationship between freedom and sin, and late treatises on the Incarnation and salvation, this collection of Anselm’s essential writings will be of interest to students of the history of philosophy and (...)
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  31.  45
    Approximate truth.Thomas Weston - 1987 - Journal of Philosophical Logic 16 (2):203 - 227.
    The technical results presented here on continuity and approximate implication are obviously incomplete. In particular, a syntactic characterization of approximate implication is highly desirable. Nevertheless, I believe the results above do show that the theory has considerable promise for application to the areas mentioned at the top of the paper.Formulation and defense of realist interpretations of science, for example, require approximate truth because we hardly ever have evidence that a particular scientific theory corresponds perfectly with a portion of the real (...)
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  32.  55
    Plato's Semantics and Plato's "Cratylus".Thomas Wheaton Bestor - 1980 - Phronesis 25 (3):306-330.
  33.  24
    From Gratification to Justice. The Tension between Anthropology and Pure Practical Reason in Kant’s Conception(s) of the Highest Good.Thomas Wyrwich - 2011 - Kant Yearbook 3 (1):91-106.
  34.  8
    The ecocultural project of human development: Why ethnography and its findings matter.Thomas S. Weisner - 1997 - Ethos: Journal of the Society for Psychological Anthropology 25 (2):177-190.
  35.  71
    Possible states of affairs.Thomas Wetzel - 1998 - Philosophical Studies 91 (1):43-60.
  36.  27
    States of affairs.Thomas Wetzel - 2003 - Stanford Encyclopedia of Philosophy.
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  37.  24
    Forming and implementing community advisory boards in low- and middle-income countries: a scoping review.Yang Zhao, Thomas Fitzpatrick, Bin Wan, Suzanne Day, Allison Mathews & Joseph D. Tucker - 2019 - BMC Medical Ethics 20 (1):1-11.
    Background Community advisory boards have expanded beyond high-income countries and play an increasing role in low- and middle-income country research. Much research has examined CABs in HICs, but less is known about CABs in LMICs. The purposes of this scoping review are to examine the creation and implementation of CABs in LMICs, including identifying frequently reported challenges, and to discuss implications for research ethics. Methods We searched five databases for publications describing or evaluating CABs in LMICs. Two researchers independently reviewed (...)
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  38.  21
    Bankers as Immoral? Some Parallels and Differences between Aquinas's Views on Usury and Marxian Views of Banking and Credit.Thomas E. Lambert - 2024 - Economic Thought 11 (2):31.
    Since ancient times the practices and ethics of bankers and banking in general have undergone a great deal of criticism. While lending is motivated by profit, and while households are not explicitly coerced into borrowing money, the justice of a system which exploits workers and at the same time encourages them to borrow money in order to maintain a certain standard of living can be viewed as sometimes unfair and perhaps immoral. The value of goods, according to St. Thomas (...)
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  39.  38
    Plato's semantics and Plato's "Parmenides".Thomas Wheaton Bestor - 1980 - Phronesis 25 (1):38-75.
  40.  39
    Vaishnavism, antievolutionism, and ambiguities: Revisiting iskcon's darwin‐skepticism.Oliver Zambon & Thomas Aechtner - 2018 - Zygon 53 (1):67-94.
    The International Society of Krishna Consciousness, commonly known as the Hare Krishna Movement, has disseminated a flurry of antievolutionist media since its inception in 1966. Such communications frequently co-opt arguments employed by Christian creationists and Intelligent Design theorists. At the same time, however, there are indications that a scattering of ISKCON publications have articulated relatively ambiguous, less oppositional statements about evolutionary theory. This article reconsiders ISKCON's Darwin-skepticism by appraising recent, largely unexamined Hare Krishna publications, as well as responses to evolutionary (...)
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  41. Anselm’s Account of Freedom.Thomas Williams & Sandra Visser - 2001 - Canadian Journal of Philosophy 31 (2):221-244.
    In this paper we offer a reconstruction of Anselm’s account of freedom that resolves various apparent inconsistencies. The linchpin of this account is the definition of freedom. Anselm argues that the power to preserve rectitude for its own sake requires the power to initiate an action of which the agent is the ultimate cause, but it does not always require that alternative possibilities be available to the agent. So while freedom is incompatible with coercion and external causal determination, an agent (...)
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  42. Philosophy screened: Experiencing the matrix.Thomas E. Wartenberg - 2003 - Midwest Studies in Philosophy 27 (1):139–152.
  43.  40
    Carl du Prel (1839–1899): explorer of dreams, the soul, and the cosmos.Thomas P. Weber - 2007 - Studies in History and Philosophy of Science Part A 38 (3):593-604.
    Nineteenth-century spiritism was a blend of religious elements, the philosophy of mind, science and popular science and contacts with extraterrestrials were a commonplace phenomenon during spiritistic séances. Using the example of Carl du Prel I show how his comprehensive mystic philosophy originated in a theory of extraterrestrial life. Carl du Prel used a Darwinian and monistic framework, theories of the unconscious and a Neo-Kantian epistemology to formulate a philosophy of astronomy and extraterrestrial life. He claimed that the mechanism of Darwinian (...)
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  44.  53
    The Ethical Values in the U.S. Agricultural and Food System.Robert L. Zimdahl & Thomas O. Holtzer - 2016 - Journal of Agricultural and Environmental Ethics 29 (4):549-557.
    Many segments of society have systems of values arising from collective beliefs and motivations. For agriculture, and our food system, increasing production to feed the growing human population clearly is a core value. However, a survey we conducted, together with a previously reported survey, showed that the curricula of most U.S. colleges of agriculture do not offer ethics courses that examine the basis of this core value or include discussion of agriculture’s ethical dilemmas such as misuse of pesticides, not progressing (...)
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  45.  6
    Putting Family Ideals into Practice: Pronaturalism in Conventional and Nonconventional California Families.Thomas S. Weisner, Mary Bausano & Madeleine Kornfein - 1983 - Ethos: Journal of the Society for Psychological Anthropology 11 (4):278-304.
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  46.  17
    The Political Background To Ovid's Tristia 2.Thomas Wiedemann - 1975 - Classical Quarterly 25 (02):264-.
    Although the view dies hard that the poetry which Ovid wrote during his years in exile at Tomi consists largely of the ‘querulous and sycophantic’ complaints of a weak man unable to come to terms with a personal disaster, it has been recognized for many years that the Tristia and the Epistolae ex Ponto are not mere expressions of emotion but are as well thought out and constructed as any other of the doctus poeta's products. Of these poems, Tristia 2 (...)
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  47.  7
    Traité de l'interprétation d'Aristote: commentaire de Thomas d'Aquin (complément de Thomas de Vio dit Cajétan).Thomas D'Aquin & Thomas Cajetan - 2018 - Paris: L'Harmattan. Edited by Guy-François Delaporte & Tommaso de Vio Cajetan.
    " En écrivant son Traité de l'Interprétation, Aristote a trempé sa plume à l'encre de son esprit! " L'antique remarque de Cassiodore vaut encore aujourd'hui tant la matière étudiée est complexe et le style ramassé. Aristote démonte les mécanismes du langage philosophique, aux confins de la linguistique et de la métaphysique. Il offre à cette occasion des développements fondateurs sur la formulation de la vérité, les règles de mise en contradiction, les propositions universelles, la contingence des jugements sur le futur, (...)
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  48.  26
    Die Eigenständigkeit des Krankheitsbegriffs in der Psychiatrie.Thomas Schramme - 2012 - Deutsche Zeitschrift für Philosophie 60 (6):955-970.
    Does the reference to a mental realm in using the notion of mental disorder lead to a dilemma that consists in either implying a Cartesian account of the mind-body relation or in the need to give up a notion of mental disorder in its own right? Many psychiatrists seem to believe that denying substance dualism requires a purely neurophysiological stance for explaining mental disorder. However, this conviction is based on a limited awareness of the philosophical debate on the mind-body problem. (...)
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  49.  27
    Motor unit firing rates during spasms in thenar muscles of spinal cord injured subjects.Inge Zijdewind, Rob Bakels & Christine K. Thomas - 2014 - Frontiers in Human Neuroscience 8.
  50.  66
    The Situated Conception of Social Power.Thomas E. Wartenberg - 1988 - Social Theory and Practice 14 (3):317-343.
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