Scientific Practice

In recent years, disagreement as a philosophical topic has started to attract considerable attention, giving rise to rich debates not only on the logical nature of disagreement but also on specifically political and religious forms of it. Moreover, in some recent documents of the Catholic Church, we see corresponding attempts at understanding religious pluralism, dialogue among religions, and doctrinal tensions that sometimes arise within various parts of the Church itself. In such debates, many assume that the realm of the humanities (...) is clearly distinct from that of the natural sciences and, as a consequence, the dynamics of disagreement within the two realms is distinct as well. This paper challenges this assumption. Sociological studies of science are undermining the idea of a strict dichotomy between the dynamics of disagreement within the sciences and that within other areas of inquiry. Engaging in comparative methodology, this paper critically evaluates the dynamics of ecclesial disagreement and the associated idea of doctrinal authority by comparing them with what happens in the sciences. (shrink)

Working from within the Lakatosian framework of scientific change, this paper seeks to gain a deeper understanding of the Jesuits’ role in the scientific revolution during the years of Galileo’s trials and the subsequent century. Their received research program was Aristotelian cosmology. Their efforts to construct protective belts to shield the core principles were fueled not only by the basic instinct to conserve but also by the impact of official prohibitions from the side of Church authorities. The paper illustrates how (...) these Church restrictions were not as paralyzing for Jesuit intellectuals as has often been thought. They left considerable space for maneuvering. The paper shows how, within this space, Jesuits were engaged mainly in the indispensable task of exhausting all the potential of Aristotelian cosmology. They did this primarily by trying to build intellectual bridges to ensure coherence between three realms of the cosmological imagination of the time: the received Aristotelian view, the new empirical data, and the realm of everyday experience. (shrink)

In order to gain a better understanding of the impact and circulation of the first edition of the Principia, we offer an analysis of public perceptions in Britain of Isaac Newton’s approach to physical inquiry in the Principia between the appearance of its first and second editions, in 1687 and 1713, respectively. We treat Newton’s readers as actors with distinctive scholarly backgrounds and interests rather than as followers or popularisers of a “Newtonian philosophy,” a label we find to be largely (...) absent in the historical record before 1713, when it was purposefully used by Roger Cotes in his preface to the second edition of the Principia. Through our survey, we gain considerable insight into how Newton’s readers characterised the Principia and its author. We establish that British readers of the first edition of the Principia ascribed a relatively stable and interrelated number of characteristics to Newton’s natural philosophical approach, although different readers emphasised different things. We also show that the most detailed accounts of Newton’s natural philosophical approach were, not surprisingly, given in polemical contexts. We find that it is only at the very end of this period, and in polemical contexts, that the notion of a “Newtonian philosophy” with a specific and pathbreaking approach to physical inquiry arose. (shrink)

Debates on dualism continue to plague psychiatry. I suggest that these debates are based on false dichotomies. According to metaphysical physicalism, reality is ultimately physical. Although this view excludes the idea of entities distinct from physical reality, it does not compel us to favour neural over psychological interventions. According to methodological dualism, both physical and mental interventions on the world can be deemed effective, and both perspectives can therefore be thought to be equally ‘real’.

This Introduction provides a rationale for a collection of new paper on Thomas Kuhn. Scholarship on Kuhn has changed dramatically in the last 20 years for numerous reasons. First, scholars studying Kuhn no longer focus narrowly on Structure of Scientific Revolutions. Scholars have been giving careful consideration to Kuhn’s later work. Second, many scholars have been drawing on the vast unpublished resources at the Thomas S. Kuhn Archive at MIT. Third, with the 50th anniversary of the publication of Structure in (...) 2012, there were quite a number of conferences held which led to the publication of a number of volumes reflecting on Kuhn’s impact in philosophy and history of science. These three developments have contributed significantly to our collective understanding of Kuhn and his theories of scientific change and scientific knowledge. Though Kuhn’s position in the philosophy of science can be difficult to gauge, by objective measures Kuhn’s impact is undeniable. Kuhn’s influence outside philosophy of science is also astounding, especially in the social sciences. So it is beyond dispute that Kuhn has had a profound and wide-ranging impact on scholarship. (shrink)

Scientific specialties are the key unit of analysis in Kuhn’s theory of scientific change. Kuhn believed that scientific specialties, in their normal phases, are characterized by theoretical monism. This is what makes scientists so efficient in realizing their epistemic goals. Recent work in the philosophy of scientific practice raises questions about the extent to which there is or needs to be consensus in science, thus challenging a key dimension of Kuhn’s view. Hasok Chang has been a leader in this project, (...) focusing attention on the benefits of pluralism. I argue that Chang and other pluralists are overcorrecting. I argue that a variety of types of pluralism can be reconciled with theoretical monism, and that theoretical monism serves significant functions, aiding scientists in the effective pursuit of their epistemic goals. Thus, I aim to set limits to pluralism. I argue that Kuhn’s theoretical monism not only has room for the sort of pluralism that Chang and others aims to defend, I also show that it presupposes such forms of pluralism. (shrink)

El propósito del ensayo es ofrecer una reflexión sobre la profesión del investigador novel desde la experiencia del autor a la luz de las ideas y reflexiones ofrecidas por Pierre Bourdieu en su obra “El oficio de científico” con cuestiones actuales y retos a los que se enfrentan la comunidad científica en el ámbito de las ciencias de la educación. El texto se articula con relación a los temas que surgen de la lectura del libro de Bourdieu que se irán (...) nutriendo de los aportes de otros textos y artículos relacionados con la materia. Como señala Martel (2016), se pretende aportar un trozo de este espejo roto que es la profesión del investigador para reconstruirlo a modo de aviso para navegantes para los que vienen detrás desde la experiencia del investigador novel. (shrink)

Mathematics is often taken to play one of two roles in the empirical sciences: either it represents empirical phenomena or it explains these phenomena by imposing constraints on them. This article identifies a third and distinct role that has not been fully appreciated in the literature on applicability of mathematics and may be pervasive in scientific practice. I call this the “bridging” role of mathematics, according to which mathematics acts as a connecting scheme in our explanatory reasoning about why and (...) how two different descriptions of an empirical phenomenon relate to each other. I discuss two bridging roles appearing in biological and physical explanations. (shrink)

Cross-disciplinary scientific collaboration is emerging as standard operating procedure for many scholarly research enterprises. And yet, the skill set needed for effective collaboration is neither taught nor mentored. The goal of the Toolbox Dialogue Initiative is to facilitate cross-disciplinary collaboration. This book, inspired by this initiative, presents dialogue-based methods designed to increase mutual understanding among collaborators so as to enhance the quality and productivity of cross-disciplinary collaboration. It provides a theoretical context, principal activities, and evidence for effectiveness that will assist (...) readers in honing their collaborative skills. (shrink)

Biological individuality is a notoriously thorny topic for biologists and philosophers of biology. In this paper we argue that biological individuality presents multiple, interconnected questions for biologists and philosophers that together form a problem agenda. Using a case study of an interdisciplinary research group in ecology, behavioral and evolutionary biology, we claim that a debate on biological individuality that seeks to account for diverse practices in the biological sciences should be broadened to include and give prominence to questions about uniqueness (...) and temporality. We show that broadening the problem agenda of biological individuality draws attention to underrecognized philosophical issues and discussions and thereby organizes and enriches the existing debate. (shrink)

A map is not its territory. Taking a map too seriously may lead to pernicious reification: map and world are conflated. As one family of cases of such reification, I focus on maps exuding the omphalos syndrome, whereby a centred location on the map is taken to be the world navel of, for instance, an empire. I build on themes from my book _When Maps Become the World_, in which I analogize scientific theories to maps, and develop the tools of (...) assumption archaeology and integration platforms. Here I argue that excavating assumptions helps fill cartographic silences, showing the limitations of perspectives often at war. Furthermore, integrating perspectives permits resisting imperial central or master images. A worthwhile future project would be a repository of world-navel maps, critically annotated with cultural context and imperial information. Mutual understanding may result from such an integration platform, perhaps implemented online or in a museum. (shrink)

There is a long tradition of preferring local theories to ones that posit lawful or causal influence at a spacetime distance. In this paper, we argue against this preference. We argue that nonlocality is scientifically unobjectionable and that nonlocal theories can be known. Scientists can gather evidence for them and confirm them in much the same way that they do for local theories. We think these observations point to a deeper constraint on scientific theorizing and experimentation: the (quasi‐) isolation of (...) causal or lawful influence. We argue that this requirement ought to replace the locality desideratum in science. We then explore the possibility that the order of explanation has been reversed: perhaps it is isolatable influence that determines what counts as local in the first place. (shrink)

Scientists represent their world, grouping and organizing phenomena into classes by means of concepts. Philosophers of science have historically been interested in the nature of these concepts, the criteria that inform their application and the nature of the kinds that the concepts individuate. They also have sought to understand whether and how different systems of classification are related and more recently, how investigative practices shape conceptual development and change. Our aim in this paper is to provide a critical overview of (...) some of the key developments in this philosophical literature and identify some interesting issues it raises about the prospects of the so-called “special sciences”, including psychiatry, psychology, and the mind-brain sciences more generally, to discover natural kinds. (shrink)

Science, technology, and professions form a system with strong interactions. Yet, these activities attack different kinds of problems which require different kinds of solutions. The problems that trigger scientific and technological research remain insufficiently solved or unsolved, therefore their possible solutions must be invented (i. e. they are partially or totally original) and, consequently, they should be tested against reality by researchers before considering them as true or useful. On the contrary, the problems that trigger professional inquiry are already solved, (...) or have at least some partial solution at hand that is available in the form of a technical protocol. This solution is applied with caution but without testing (i. e. the professional assumes that the solution works because it was already challenged by researchers). Moreover, science and technology tackle unsolved inverse problems, which allow the radical advancement of knowledge, and genuine innovation. A science policy based on a clear distinction between creative and routine activities (i. e. a cre- atively friendly policy) offers an opportunity for societies to reach value-added innovative economic and integral development. (shrink)

La science, la technologie et les professions forment un système de fortes interactions. Pourtant, ces activités s’attaquent à différents types de problèmes qui nécessitent différentes solutions. Les problèmes qui aiguillonnent la recherche scientifique et technologique demeurent insuffisamment résolus ou non résolus, donc leurs possibles solutions doivent être inventées (c.-à-d. qu’elles sont partiellement ou totalement originales) et, par conséquent, elles doivent être testées contre la réalité par les chercheurs avant de les considérer comme vraies ou utiles. Par contre, les problèmes qui (...) aiguillonnent une investigation professionnelle sont déjà résolus ou une solution partielle est disponible sous la forme d’un protocole technique. Cette solution est appliquée avec prudence sans être testée (c’est-à-dire que le professionnel suppose que la solution fonctionne parce qu’elle a déjà été mise à l’épreuve par les chercheurs). De plus, la science et la technologie s’attaquent à des problèmes inverses non résolus, ce qui permet l’avancement radical des connaissances par de véritables innovations. Une politique scientifique fondée sur une dis- tinction claire entre les activités créatives et les activités routinières (c.-à-d. une politique respectueuse de la créativité) offre à la société la possibilité d’un développement économique et intégral à valeur ajoutée. (shrink)

According to the homeostatic property cluster family of accounts, one of the main conditions for groups of properties to count as natural is that these properties be frequently co-instantiated. I argue that this condition is, in fact, not necessary for natural-kindness. Furthermore, even when it is present, the focus on co-occurrence distorts the role natural kinds play in science. Co-occurrence corresponds to what information theorists call redundancy: observing the presence of some of the properties in a frequently co-occurrent cluster makes (...) observations of other members of the cluster comparatively uninformative. Yet, scientific practice often, and increasingly often, singles out as natural groups of properties that are not redundant, but synergic: instantiations of properties in synergic clusters are not necessarily informative about instantiations of other properties in the cluster; rather, it is their joint instantiation that plays the explanatory role for which the natural kind is recruited. (shrink)

Moral and political philosophers commonly appeal to moral “intuitions” at crucial points in their reasoning. This chapter considers recent challenges to this practice—here referred to as “the Method”—based in empirical studies of moral intuitions. It contends that such studies do not justify radical or revisionary conclusions about the Method. A method is aimed at achieving certain goals. The key issue is the nature of the goals in relation to which the Method is to be evaluated. This chapter argues that the (...) relevant goal is not the “realist goal” of discovering the truth about moral and political matters. The central point is that, the chapter argues, the systematic philosophical study of moral and political questions would be worthwhile even if it turned out that moral realism cannot be vindicated or that the Method cannot be vindicated in relation to the realist goal. If this is correct, then the goal relative to which it is crucial to vindicate the Method is not the realist goal. A Rawlsian view is more plausible, according to which the relevant goal is to “characterize our moral sensibility” as it would be in “reflective equilibrium.” It turns out, however, that this Rawlsian view has some, perhaps unwelcome, deflationary implications. (shrink)

Behavioral genetic (BG) research has yielded many important discoveries about the origins of human behavior, but offers little insight into how we might improve outcomes. We posit that this gap in our knowledge base stems in part from the epidemiologic nature of BG research questions. Namely, BG studies focus on understanding etiology as it currently exists, rather than etiology in environments that could exist but do not as of yet (e.g., etiology following an intervention). Put another way, they focus exclusively (...) on the etiology of “what is” rather than “what could be”. The current paper discusses various aspects of this field-wide methodological reality, and offers a way to overcome it by demonstrating how behavioral geneticists can incorporate an experimental approach into their work. We outline an ongoing study that embeds a randomized intervention within a twin design, connecting “what is” and “what could be” for the first time. We then lay out a more general framework for a new field—experimental BGs—which has the potential to advance both scientific inquiry and related philosophical discussions. (shrink)

Well-known epistemologies of science have implications for how best to understand knowledge transfer (KT). Yet, to date, no serious attempt has been made explicate these particular implications. This paper infers views about KT from two popular epistemologies; what we characterize as incommensurabilitist views (after Devitt 2001; Bird 2002, 2008; Sankey and Hoyningen-Huene 2013) and voluntarist views (after van Fraassen 1984; Dupré 2001; Chakravartty 2015). We argue views of the former sort define the methodological, ontological, and social conditions under which research (...) operates within ‘different worlds’ (to use Kuhn’s expression), and entail that genuine KTs under those conditions should be difficult or even impossible. By contrast, more liberal voluntarist views recognize epistemological processes that allow for transfers across different sciences even under such conditions. After outlining these antithetical positions, we identify two kinds of KTs of two kinds present in well-known episodes in the history of ecology—specifically, successful model transfers from chemical kinetics and thermodynamics into areas of ecological research—which reveal significant limitations of incommensurabilitist views. We conclude by discussing how the selected examples support a pluralistic voluntarism regarding KT. (shrink)

A crucial aspect of scientific realism is what do we mean by true. In Luk’s theory and model of scientific study, a theory can be believed to be “true” but a model is only accurate. Therefore, what do we mean by a “true” theory in scientific realism? Here, we focus on exploring the notion of truth by some thought experiments and we come up with the idea that truth is related to what we mean by the same. This has repercussion (...) to the repeatability of the experiments and the predictive power of scientific knowledge. Apart from sameness, we also found that truth is related to the granularity of the observation, the limit of detection, the distinguishability of the objects in theory, the simultaneous measurements of objects/processes, the consistencies of the theory and the one-to-one correspondence between terms/events and objects/processes, respectively. While there is no guarantee that we can arrive at the final “true” theory, we have a process/procedure with more and more experiments together with our own ingenuity, to direct us towards such a “true” theory. For quantum mechanics, since a particle is also regarded as a wave, quantum mechanics cannot be considered as a true theory based on the correspondence theory of truth. Failing this, truth may be defined by the coherence theory of truth which is similar to the coherence of beliefs. However, quantum mechanics may not be believed to be a true theory based on the coherence theory of truth because wave properties and particle properties may contradict. Further research is needed to address this problem if we want to regard quantum mechanics as a “true” theory. (shrink)

Conceptual analysis as a method of inquiry has long enjoyed popularity in analytic philosophy, including the philosophy of science. In this article I offer a perspective on the ways in which the method of conceptual analysis has been used, and distinguish two broad kinds, namely philosophical and empirical conceptual analysis. In so doing I outline a historical trend in which non-naturalized approaches to conceptual analysis are being replaced by a variety of naturalized approaches. I outline the basic characteristics of these (...) approaches with illustrative examples, arguing that recent developments in the philosophy of science show that in order to achieve a more adequate understanding of scientific endeavour we need to prioritize the naturalized accounts of the method. (shrink)

The production of scientific instruments in America was neither a postwar phenomenon nor dramatically different from that of several other developed countries. It did, however, undergo a step-change in direction, size and style during and after the war. The American scientific instrument industry after 1945 was intimately dependent on, and shaped by, prior American and European experience. This was true of the specific genres of instrument produced commercially; to links between industry and science; and, just as importantly, to manufacturing practices (...) and cultures. I will argue that, despite the new types of instrument commercialized after the war, this historical continuity of links with science and scientists guided and constrained the design and manufacture of these products. Nevertheless, new designers, manufacturers and customers gradually transformed the culture of scientific instruments in the second half of the century. -/- This chapter deals with a subset of the American instrument industry, namely the measuring and monitoring instruments manufactured for scientific use. Even with the specification of ‘scientific’ instruments, however, these borders are rather artificial and unclear: instrument making from the seventeenth through the twentieth century has generally involved the fabrication of both standard products and custom-made devices for scientific use.2 In this context of sales quantities, ‘scientific’ instruments have often been defined as low-volume, special-order or custom devices. In a similar vein, ‘scientific’ instruments were commonly distinguished from ‘production’ instruments by context of usage, namely their very absence from – and indeed irrelevance to – production environments. This demarcation according to customer and environment was mirrored in at least one furth er respect: the training of their users. The classification into ‘scientific’ and ‘engineering’ applications was as fluid as the relationship between American universities and technical industries themselves.Despite these complementary definitions, the notion of the ‘scientific instrument’ was beginning to prove inadequate even at the turn of the twentieth century, and dramatically so when discussing the post-Second World War period. Definitions altered qualitatively after the Second World War in at least three further ways: (a) new genres of device altered the scope of the scientific instrument; (b) the contribution of State and military sponsorship of new forms of instrument became significant; and, (c) the postwar demand for specialist instruments increased rapidly, owing to wartime innovation, new applications and new customers. I will explore the evolution of instrument manufacturing in this changing context of new technology, funding, development and markets. (shrink)

Cancer research is experiencing ‘paradigm instability’, since there are two rival theories of carcinogenesis which confront themselves, namely the somatic mutation theory and the tissue organization field theory. Despite this theoretical uncertainty, a huge quantity of data is available thanks to the improvement of genome sequencing techniques. Some authors think that the development of new statistical tools will be able to overcome the lack of a shared theoretical perspective on cancer by amalgamating as many data as possible. We think instead (...) that a deeper understanding of cancer can be achieved by means of more theoretical work, rather than by merely accumulating more data. To support our thesis, we introduce the analytic view of theory development, which rests on the concept of plausibility, and make clear in what sense plausibility and probability are distinct concepts. Then, the concept of plausibility is used to point out the ineliminable role played by the epistemic subject in the development of statistical tools and in the process of theory assessment. We then move to address a central issue in cancer research, namely the relevance of computational tools developed by bioinformaticists to detect driver mutations in the debate between the two main rival theories of carcinogenesis. Finally, we briefly extend our considerations on the role that plausibility plays in evidence amalgamation from cancer research to the more general issue of the divergences between frequentists and Bayesians in the philosophy of medicine and statistics. We argue that taking into account plausibility-based considerations can lead to clarify some epistemological shortcomings that afflict both these perspectives. (shrink)

Bayesian confirmation theory is a leading theory to decide the confirmation/refutation of a hypothesis based on probability calculus. While it may be much discussed in philosophy of science, is it actually practiced in terms of hypothesis testing by scientists? Since the assignment of some of the probabilities in the theory is open to debate and the risk of making the wrong decision is unknown, many scientists do not use the theory in hypothesis testing. Instead, they use alternative statistical tests that (...) can measure the risk or the reliability in decision making, circumventing some of the theoretical problems in practice. Therefore, the theory is not very popular in hypothesis testing among scientists at present. However, there are some proponents of Bayesian hypothesis testing, and software packages are made available to accelerate utilization by scientists. Time will tell whether Bayesian confirmation theory can become both a leading theory and a widely practiced method. In addition, this theory can be used to model the belief of scientists when testing hypotheses. (shrink)

Holograms have been in the public eye for over a half-century, but their influences have deeper cultural roots. No other visual experience is quite like interacting with holograms; no other cultural product melds the technological sublime with magic and optimism in quite the same way. As holograms have evolved, they have left their audiences alternately fascinated, bemused, inspired or indifferent. From expressions of high science to countercultural art to consumersecurity, holograms have represented modernity, magic and materialism. Their most pervasive impact (...) has been to galvanise hopeful technological dreams. Engineers, artists, hippies and hobbyists have played with, and dreamed about, holograms. This book explores how holograms found a place in distinct cultural settings. It is aimed at readers attracted to pop culture, visual studies and cultural history, scholars concerned with media history, fine art and material studies and, most of all, cross-disciplinary audiences intrigued about how this ubiquitous but still-mysterious visual medium grew up in our midst and became entangled in our culture. This book explores the technical attractions and cultural uses of the hologram, how they were shaped by what came before them, and how they have matured to shape our notional futures. Today, holograms are in our pockets (as identity documents) and in our minds (as gaming fantasies and faux hologram performers). Why arent they more often in front of our eyes? (shrink)

The first nuclear engineers emerged from the Manhattan Project in the USA, UK and Canada, but remained hidden behind security for a further decade. Cosseted and cloistered by their governments, they worked to explore applications of atomic energy at a handful of national labs. This unique bottom-up history traces how the identities of these unusually voiceless experts - forming a uniquely state-managed discipline - were shaped in the context of pre-war nuclear physics, wartime industrial management, post-war politics and utopian energy (...) programmes. Even after their eventual emergence at universities and companies, nuclear workers carried the enduring legacy of their origins. Their shared experiences shaped not only their identities, but our collective memories of the late twentieth century. And as illustrated by the Fukushima accident seven decades after the Manhattan project began, this book explains why they are still seen conflictingly as selfless heroes or as mistrusted guardians of a malevolent genie. (shrink)

The paper takes off from the suggestion of Jouni-Matti Kuukkanen that Kuhn’s account of science may be understood in coherentist terms. There are coherentist themes in Kuhn’s philosophy of science. But one crucial element is lacking. Kuhn does not deny the existence of basic beliefs which have a non-doxastic source of justification. Nor does he assert that epistemic justification only derives from inferential relationships between non-basic beliefs. Despite this, the coherentist interpretation is promising and I develop it further in this (...) paper. I raise the question of whether Kuhn’s account of science can deal with the input objection to coherentism. I argue that the role played by problems in Kuhn’s theory of science ensures that there is input from the external world into scientists’ belief-systems. I follow Hoyningen-Huene in pointing to the causal role played by the external world in determining perceptual states. I next turn to the question of whether Kuhn’s rejection of foundationalism implies coherentism. I argue that Kuhn’s rejection of the one-to-one relation between object and experience is compatible with a foundationalist account of justification. Nor does Kuhn’s rejection of the given entail the same coherentist implications as Sellars’ critique of the myth of the given. (shrink)

Science communication via testimony requires a certain level of trust. But in the context of ideologically-entangled scientific issues, trust is in short supply—particularly when the issues are politically ‘entangled’. In such cases, cultural values are better predictors than scientific literacy for whether agents trust the publicly-directed claims of the scientific community. In this paper, we argue that a common way of thinking about scientific literacy—as knowledge of particular scientific facts or concepts—ought to give way to a second-order understanding of science (...) as a process as a more important notion for the public’s trust of science. (shrink)

Sensations can occur in the absence of perception and yet be experienced ‘as if’ seen, heard, tasted, or otherwise perceived. Two concepts used to investigate types of these sensory-like mental phenomena (SLMP) are mental imagery and hallucinations. Mental imagery is used as a concept for investigating those SLMP that merely resemble perception in some way. Meanwhile, the concept of hallucinations is used to investigate those SLMP that are, in some sense, compellingly like perception. This may be a difference of degree. (...) Attempts to reliably differentiate between instances of each type of SLMP remain unresolved. Despite this, the concepts of mental imagery and hallucinations are each routinely used independently of the other. These uses are especially interesting in those published accounts of experiments where equivalent findings about the neuroanatomical correlates of SLMP are reported in support of diverging knowledge-claims about the role of SLMP in neurocognitive processes. This practice presents a puzzle. To examine one aspect of this puzzle, I compare the uses of these two scientific concepts in three ways: examining their roles in differentiating between types of SLMP; exploring how their respective historical developments intersect; and analysing their contributions in neuroimaging experiments. In presenting this series of comparative analyses, I will draw on three themes from historical, philosophical, and social studies of scientific practices: interest in material contributions to knowledge; accounts of how concepts are used in experiments; and explorations of the historical conditions within which current practices emerge. Building on this literature, my comparative analyses supports five related claims. My first claim is that the concepts of mental imagery and hallucinations are each used as independent tools in neuroimaging experiments. My second claim is that, as experimental tools, the concepts of mental imagery and hallucinations are each used for investigating discrete epistemic goals. My third claim is that there are implicit interdependent associations that structure the uses of these two concepts as tools for independently investigating these discrete epistemic goals in neuroimaging experiments. This third claim rests on my analyses of both past and present uses of each concept. Firstly, as seen in their intersecting histories, there are disciplined performances of using the concepts of mental imagery and hallucinations that carry-along shared associations about the mediating role of SLMP in thought. Secondly, these interdependent ‘mediator-view’ associations continue to structure the independent uses of each concept as a tool for investigating SLMP in pursuit of specific goals. Taking this further, my fourth claim is that recognising the structured uses of the concepts of mental imagery and hallucinations can help to account for how equivalent SLMP-neuro-correlates are generated in support of diverging knowledge-claims. Finally, my fifth claim is that the structured uses of these concepts as tools can contribute to experiments in ways analogous to, yet not equivalent with, the active contributions of material instruments. Bringing these claims together, I argue that the concepts of mental imagery and hallucinations operate as structured tools that can actively contribute to the knowledge generated by neuroimaging experiments. In presenting this argument I seek to demonstrate that examining the structured uses of concepts as tools can complement existing approaches to studying how the heterogeneous dynamics of experimental practices can come to contribute to scientific knowledge in unintended ways. (shrink)

Our paper studies the anatomy of the discovery of the Higgs boson at the Large Hadron Collider and its influence on the broader model landscape of particle physics. We investigate the phases of this discovery, which led to a crucial reconfiguration of the model landscape of elementary particle physics and eventually to a confirmation of the standard model. A keyword search of preprints covering the electroweak symmetry breaking sector of particle physics, along with an examination of physicists own understanding of (...) the discovery as documented in semiannual conferences, has allowed us an empirical investigation of its model dynamics. From our analyses we draw two main philosophical lessons concerning the nature of scientific reasoning in a complex experimental and theoretical environment. For one, from a confirmation standpoint, some SM alternatives could be considered even more confirmed by the Higgs discovery than the SM. Nevertheless, the SM largely remains the commonly accepted account of EWSB. We present criteria for comparing degrees of confirmation and expose some limits of a purely logical approach to understanding the Higgs discovery as a victory for the SM. Second, we understand the persistence of SM alternatives in the face of disfavourable evidence by borrowing the Lakatosian concept of a research programme, where the core idea behind a group of models survives, while other aspects adapt to incoming data. In order to apply this framework to the model landscape of EWSB, we must introduce a new category of research programme, the model-group, and we test its viability using the example of composite Higgs models. (shrink)

This paper examines a specific kind of part-whole relations that exist in the molecular genetic domain. The central question is under which conditions a particular molecule, such as a DNA sequence, is a biological part of the human genome. I address this question by analyzing how biologists in fact partition the human genome into parts. This paper thus presents a case study in the metaphysics of biological practice. I develop a metaphysical account of genomic parthood by analyzing the investigative and (...) reasoning practices in the ENCODE (ENCyclopedia Of DNA Elements) project. My account reveals two conditions that determine whether a molecule is a part of the human genome (i.e., a genomic part). First, genomic parts must possess a causal role function in the genome as a whole, that is, their functions must contribute to the genome directing the overall functioning of the cell. Second, genomic parts must have a specific chemical structure and be actual segments of the DNA sequence of the genome. (shrink)

The replication crisis has prompted many to call for statistical reform within the psychological sciences. Here we examine issues within Frequentist statistics that may have led to the replication crisis, and we examine the alternative—Bayesian statistics—that many have suggested as a replacement. The Frequentist approach and the Bayesian approach offer radically different perspectives on evidence and inference with the Frequentist approach prioritising error control and the Bayesian approach offering a formal method for quantifying the relative strength of evidence for hypotheses. (...) We suggest that rather than mere statistical reform, what is needed is a better understanding of the different modes of statistical inference and a better understanding of how statistical inference relates to scientific inference. (shrink)

Dieser Aufsatz beschreibt und erörtert fünf Aspekte der gegenwärtigen Wissenschaft: Verfahren, Zwiespalt, Schweigen, Hoffnung, und Probieren.

Scientists’ graphical practices have recently become a target of inquiry in the philosophy of science, and in the cognitive sciences. Here I supplement our understanding of graphical practices via a case study of how researchers crafted the graphics for scientific publication in the field of circadian biology. The case highlights social aspects of graphical production which have gone understudied e especially concerning the negotiation of publication. I argue that it also supports a challenge to the claim that empirically-informed “cognitive design (...) principles” offer an apt understanding of the norms of success which govern good scientific graphic design to communicate data and hypotheses to other experts. In this respect, the case-study also illustrates how “descriptive” studies of scientific practice can connect with normative issues in philosophy of science, thereby addressing a central concern in recent discussions of practice-oriented philosophy of science. (shrink)

Two developments have been of crucial significance to create the today's relation of theoretical jurisprudence and the practical pursuit of law:1. The process of forming a jurisprudence basing on scientific methods around 1800. This process is particularly based on the following epistemological changes: The late 18th century gave birth to the idea of a system of science as an unchangeable context of science in abstracto. Therefore the practical application of parts of this system appeared no longer as an independent science. (...) Besides the late 18th century gave birth to the distinction between scientific ability and practical ability . Finally the late 18th century established criteria of a scientific method — necessity, reasoning, systematics —, which the practical application could not satisfy. Jurisprudence absorbed these epistemological changes in the late 18th century and regarded itself as a science. Therefore the legal science dismissed the “applied jurisprudence” that is to say the practical pursuit of law . 2. The change in the relation of academic and practical education of lawyers around and after 1800: The practical education was dislodged from the universities and found its place in the practical judicial training after the first state examination . This “two-step-education” was established first in Prussia and since 1879 everywhere in Germany. (shrink)

Thought experiments are one among the oldest and effectively employed tools of scientific reasoning. Hacking (Philos Sci 2:302–308, 1992) argues that thought experiments in contrast to real experiments do not have a life of their own. In this paper, I attempt to show that contrary to Hacking’s contentions, thought experiments do have a life of their own. The paper is divided into three main sections. In the first section, I review the reasons that Hacking sets out for believing in the (...) life of experiments. Second section discusses Hacking’s characterization of thought experiments. The section also reviews his arguments for denying a life to thought experiments. In the third section, I argue for a life of thought experiments. In this section, I discuss the historical evolution of the EPR thought experiment and Galileo’s Free Falling Bodies in detail to show the untenability of Hacking’s arguments. The third section is followed by a conclusion that thought experiments do have a life of their own. (shrink)

The physician and philosopher Johannes Jessenius, an enthusiastic anatomist in Wittenberg, often had to defend his anatomical practices against Lutheran orthodoxy, as is apparent from the invitations he wrote concerning his dissections. His most systematic defence can be found in the introduction to his description of the dissection performed in Prague in 1600, where he provides three different strategies for the justification of anatomical research. The first method traditionally builds on the use of the ancient dictum ‘know thyself;’ the second (...) strategy is based on teleology, which Jessenius adopted from Vesalius’ work; and the final method is derived from the philosophical tradition of the Renaissance. Jessenius makes use of the concept of the dignity of man in order to support the dignity of anatomical practice. The fundamental meaning of the philosophical framework of Jessenius’s approach emerges from the comparison with both Andreas Vesalius, whose Fabric was one model for Jessenius’s anatomical work, and with the speech delivered by Adamus Zaluzanius a Zaluzaniis prior to Jessenius’s Prague anatomical performance. (shrink)

Nobody wants unnatural kinds. Just as we prefer all natural ingredients in our food, so also we prefer natural kinds in our ontology and epistemology. Philosophers contrast natural with merely “conventional” kinds, and scientists advocate for natural rather than artificial classification systems. A central plank of the desired naturalness is “mind independence”—the property of existing independent of human interests and desires. Natural kinds are discovered, not made. They reflect the structure of the world (“nature’s joints”) and for this reason justify (...) the practice of inductive inference. Conventional kinds, by contrast, are dependent on human classificatory activities. They are created with an end in view and therefore lack “a real existence in nature” (J. S. Mill, A System of Logic, Ratiocinative and Inductive [London: Longmans, 1843], 1:165). Since their existence is dependent on human activities, nominal kinds need not track nature’s joints. Because scientists are interested in groupings that really exist in nature—not those fabricated for human purposes—their classificatory practices aim to achieve natural-kind classifications. Achieving these classifications is crucial to the success of science. (shrink)