In the current model of visual transduction, the lifetime of active cGMP phosphodiesterase depends upon the period of its interaction with GTP-bound transducin. If recoverin regulates the lifetime of light-activated cGMP phosphodiesterase through inhibition of rhodopsin phosphorylation, rhodopsin should directly interact with cGMP phosphodiesterase and/or GTP-bound transducin complexed with cGMP phosphodiesterase. Is this true?

The goal of this article is to shed light on Deep Brain Stimulation (DBS) postoperative suicidality risk factors within Treatment Resistant Depression (TRD) patients, in particular by focusing on the ethical concern of enrolling patient with history of self-estrangement, suicide attempts and impulsive–aggressive inclinations. In order to illustrate these ethical issues we report and review a clinical case associated with postoperative feelings of self-estrangement, self-harm behaviours and suicide attempt leading to the removal of DBS devices. Could prospectively identifying (...) and excluding patients with suicidality risk factors from DBS experimental trials—such as history of self-estrangement, suicide attempts and impulsive–aggressive inclinations—lead to minimizing the risk of suicidality harm? (shrink)

Neural impulses from the senses to the brain convey information, not sensation. The direct electrical stimulation of the cortex produces sensations. Hence, such sensations are evoked in the brain, and not received from the senses, nor from the outside world through the senses. More specifically, the experience of light is evoked in the brain and not received from the eyes. Consequently, the born blind, too, would experience light in response to electrical brain stimulation. The luminosity of (...) light is not a property of electromagnetic radiation. If the experience of light is private, then so are the visual observations it makes possible. (shrink)

Despite growing evidence that a significant number of patients living with Parkison’s disease experience neuropsychiatric changes following Deep Brain Stimulation treatment, the phenomenon remains poorly understood and largely unexplored in the literature. To shed new light on this phenomenon, we used qualitative methods grounded in phenomenology to conduct in-depth, semi-structured interviews with 17 patients living with Parkinson’s Disease who had undergone DBS. Our study found that patients appear to experience postoperative DBS-induced changes in the form of self-estrangement. Using (...) the insights from patients’ subjective perceptions of postoperative self-change provides a potent explanation of potential DBS-induced self-estrangement. (shrink)

Flickering light induces visual hallucinations in human observers. Despite a long history of the phenomenon, little is known about the dependence of flicker-induced subjective impressions on the flicker frequency. We investigate this question using Ganzfeld stimulation and an experimental paradigm combining a continuous frequency scan with a focus on re-occurring, whole percepts. On the single-subject level, we find a high degree of frequency stability of percepts. To generalize across subjects, we apply two rating systems, a set of complex (...) percept classes derived from subjects’ reports and an enumeration of elementary percept features, and determine distributions of occurrences over flicker frequency. We observe a stronger frequency specificity for complex percept classes than elementary percept features. Comparing the similarity relations among percept categories to those among frequency profiles, we observe that though percepts are preferentially induced by particular frequencies, the frequency does not unambiguously determine the experienced percept. (shrink)

Deep brain stimulation (DBS) is an effective treatment for the debilitating motor symptoms of Parkinson’s disease and other neurological disorders. However, clinicians and commentators have noted that DBS recipients have not necessarily experienced the improvements in quality of life that would be expected, due in large part to what have been described as the ‘psychosocial’ impacts of DBS. The premise of this paper is that, in order to realise the full potential of DBS and similar interventions, clinical services need (...) to be arranged in such a way that these psychosocial dimensions are recognised and managed. Our starting point is that the psychosocial effects of DBS ‘in the field’ present us with analytically-useful disruptions: they disturb and foreground deeply held assumptions relating to the individual, health and its treatment, and which in a crude form manifest as the myth of technological solutionism within health care. Drawing on scholarship in medical sociology and science and technology studies (STS), we argue that DBS brings to the fore the relational dimensions of personhood, and demonstrates the emotional and social turmoil that can result if the relational dimensions of personhood are ignored by clinical services. In light of this, we argue that DBS should be implemented within a regime of care. Drawing on ethnographic research of a paediatric DBS clinical service, we provide an example of a regime of care, and conclude by reflecting on what other DBS services might learn from this paediatric service. (shrink)

In this article, I explore select case studies of Parkinson patients treated with deep brain stimulation in light of the notions of alienation and authenticity. While the literature on DBS has so far neglected the issues of authenticity and alienation, I argue that interpreting these cases in terms of these concepts raises new issues for not only the philosophical discussion of neuro-ethics of DBS, but also for the psychological and medical approach to patients under DBS. In particular, I (...) suggest that the experience of alienation and authenticity varies from patient to patient with DBS. For some, alienation can be brought about by neurointerventions because patients no longer feel like themselves. But, on the other hand, it seems alienation can also be cured by DBS as other patients experience their state of mind as authentic under treatment and retrospectively regard their former lives without stimulation as alienated. I argue that we must do further research on the relevance of authenticity and alienation to patients treated with DBS in order to gain a deeper philosophical understanding, and to develop the best evaluative criterion for the behavior of DBS patients. (shrink)

Background -/- Innovative neurosurgical treatments present a number of known risks, the natures and probabilities of which can be adequately communicated to patients via the standard procedures governing obtaining informed consent. However, due to their novelty, these treatments also come with unknown risks, which require an augmented approach to obtaining informed consent. -/- Objective -/- This paper aims to discuss and provide concrete procedural guidance on the ethical issues raised by serious unexpected complications of novel deep brain stimulation treatments. (...) -/- Approach -/- We illustrate our analysis using a case study of the unexpected development of recurrent stereotyped events in patients following the use of deep brain stimulation (DBS) to treat severe chronic pain. Examining these unexpected complications in light of medical ethical principles, we argue that serious complications of novel DBS treatments do not necessarily make it unethical to offer the intervention to eligible patients. However, the difficulty the clinician faces in determining whether the intervention is in the patient's best interests generates reasons to take extra steps to promote the autonomous decision making of these patients. -/- Conclusion and recommendations -/- We conclude with clinical recommendations, including details of an augmented consent process for novel DBS treatment. (shrink)

The use of transcranial Electrical Stimulation in the modulation of cognitive brain functions to improve neuropsychiatric conditions has extensively increased over the decades. tES techniques have also raised new challenges associated with study design, stimulation protocol, functional specificity, and dose-response relationship. In this paper, we addressed challenges through the emerging methodology to investigate the dose-response relationship of High Definition-transcranial Direct Current Stimulation, identifying the role of negative valence in tinnitus perception. In light of the neurofunctional testable (...) framework and tES application, hypotheses were formulated to measure clinical and surrogate endpoints. We posited that conscious pairing adequately pleasant stimuli with tinnitus perception results in correction of the loudness misperception and would be reinforced by concurrent active HD-tDCS on the left Dorsolateral Prefrontal Cortex. The dose-response relationship between HD-tDCS specificity and the loudness perception is also modeled. We conducted a double-blind, randomized crossover pilot study with six recruited tinnitus patients. Accrued data was utilized to design a well-controlled adaptive seamless Bayesian dose-response study. The sample size and optimum interims were anticipated for adaptive decision-making about efficacy, safety, and single session dose parameters. Furthermore, preliminary pilot study results were sufficient to show a significant difference within the longitudinally detected self-report tinnitus loudness between before and under positive emotion induction. This study demonstrated a research methodology used to improve emotion regulation in tinnitus patients. In the projected method, positive emotion induction is essential for promoting functional targeting under HD-tDCS anatomical specificity to indicate the efficacy and facilitate the dose-finding process. The continuous updating of prior knowledge about efficacy and dose during the exploratory stage adapts the anticipated dose-response model. Consequently, the effective dose range to make superiority neuromodulation in correcting loudness misperception of tinnitus will be redefined. Highly effective dose adapts the study to a standard randomized trial and transforms it into the confirmatory stage in which active HD-tDCS protocol is compared with a sham trial. Establishing the HD-tDCS intervention protocols relying on this novel method provides reliable evidence for regulatory agencies to approve or reject the efficacy and safety. Furthermore, this paper supports a technical report for designing multimodality data-driven complementary investigations in emotion regulation, including EEG-driven neuro markers, Stroop-driven attention biases, and neuroimaging-driven brain network dynamics. (shrink)

Using P300-based brain–computer interfaces in daily life should take into account the user’s emotional state because various emotional conditions are likely to influence event-related potentials and consequently the performance of P300-based BCIs. This study aimed at investigating whether external emotional stimuli affect the performance of a P300-based BCI, particularly built for controlling home appliances. We presented a set of emotional auditory stimuli to subjects, which had been selected for each subject based on individual valence scores evaluated a priori, while they (...) were controlling an electric light device using a P300-based BCI. There were four conditions regarding the auditory stimuli, including high valence, low valence, noise, and no sound. As a result, subjects controlled the electric light device using the BCI in real time with a mean accuracy of 88.14%. The overall accuracy and P300 features over most EEG channels did not show a significant difference between the four auditory conditions. When we measured emotional states using frontal alpha asymmetry and compared FAA across the auditory conditions, we also found no significant difference. Our results suggest that there is no clear evidence to support a hypothesis that external emotional stimuli influence the P300-based BCI performance or the P300 features while people are controlling devices using the BCI in real time. This study may provide useful information for those who are concerned with the implementation of a P300-based BCI in practice. (shrink)

In this article, I examine children's reported experiences with stimulant drug treatments for attention deficit hyperactivity disorder in light of bioethical arguments about the potential threats of psychotropic drugs to authenticity and moral agency. Drawing on a study that involved over 150 families in the USA and the UK, I show that children are able to report threats to authenticity, but that the majority of children are not concerned with such threats. On balance, children report that stimulants improve their (...) capacity for moral agency, and they associate this capacity with an ability to meet normative expectations. I argue that although under certain conditions stimulant drug treatment may increase the risk of a threat to authenticity, there are ways to minimise this risk and to maximise the benefits of stimulant drug treatment. Medical professionals in particular should help children to flourish with stimulant drug treatments, in good and in bad conditions. (shrink)

IntroductionDeep brain stimulation (DBS) is utilized to treat pediatric refractory dystonia and its use in pediatric patients is expected to grow. One important question concerns the impact of hope and unrealistic optimism on decision-making, especially in “last resort” intervention scenarios such as DBS for refractory conditions.ObjectiveThis study examined stakeholder experiences and perspectives on hope and unrealistic optimism in the context of decision-making about DBS for childhood dystonia and provides insights for clinicians seeking to implement effective communication strategies.Materials and MethodsSemi-structured (...) interviews with clinicians (n = 29) and caregivers (n = 44) were conducted, transcribed, and coded.ResultsUsing thematic content analysis, four major themes from clinician interviews and five major themes from caregiver interviews related to hopes and expectations were identified. Clinicians expressed concerns about caregiver false hopes (86%, 25/29) and desperation (68.9%, 20/29) in light of DBS being a last resort. As a result, 68.9% of clinicians (20/29) expressed that they intentionally tried to lower caregiver expectations about DBS outcomes. Clinicians also expressed concern that, on the flip side, unrealistic pessimism drives away some patients who might otherwise benefit from DBS (34.5%, 10/29). Caregivers viewed DBS as the last option that they had to try (61.3%, 27/44), and 73% of caregivers (32/44) viewed themselves as having high hopes but reasonable expectations. Fewer than half (43%, 19/44) expressed that they struggled setting outcome expectations due to the uncertainty of DBS, and 50% of post-DBS caregivers (14/28) expressed some negative feelings post treatment due to unmet expectations. 43% of caregivers (19/44) had experiences with clinicians who tried to set low expectations about the potential benefits of DBS.ConclusionThoughtful clinician-stakeholder discussion is needed to ensure realistic outcome expectations. (shrink)

In this article we report relevant data that shed light on the topic of hope and patients’ expectations in the use of DBS, for standard, approved, and established indications, based on a broader qualitative study on the ethical and social challenges that healthcare providers face in the field of DBS.

If the notion of free will is to be retained by philosophers, psychiatrists and psychologists, then it will be a free will which is essentially non-conscious. The purpose of this paper is to demonstrate that a conscious free will (in the sense of consciousness initiating action) is incompatible with the evidence of neuroscience, and the phenomenology described in the literature of normal creativity, psychotic passivity, and the neurological syndrome of the alien limb or hand. In particular the work of Libet (...) and others who have directly stimulated the brain and measured activity from its surface leads to the conclusion that subjective states (be they sensory or intentional) are preceded by predictive neural activity. Subjective phenomenology is temporally distinct from the initiation of “voluntary” action. In addition it will be argued that free will is more than a belief and that it comprises a perceptual sensorimotor component. Free will is conceptualized as a three component phenomenon consisting of a perceptual, non-linguistic experience of freedom, an experiential belief which is linguistic, and related to a specified action in time, and an abstract belief which is linguistic but remote from any particular action and akin to philosophical discourse (the abstract belief or otherwise, in free will). A theoretical explanation of some of the pathological phenomenology of possession of action is offered in terms of temporal considerations. The direction of action within mental/virtual space is hypothesized to be a function of the temporal sequence of its initiation and awareness of the latter “reaching” consciousness. It is suggested that perturbation of this temporal sequence may lead to the misattribution of host-as-alien-initiated action. Work of this kind, which is beyond subjective introspection, is necessary if we are to develop adequate models to use in conjunction with modern investigation techniques. (shrink)

Our understanding of human visual perception generally rests on the assumption that conscious visual states represent the interaction of spatial structures in the environment and our nervous system. This assumption is questioned by circumstances where conscious visual states can be triggered by external stimulation which is not primarily spatially defined. Here, subjective colors and forms are evoked by flickering light while the precise nature of those experiences varies over flicker frequency and phase. What’s more, the occurrence of one (...) subjective experience appears to be associated with the occurrence of others. While these data indicate that conscious visual experience may be evoked directly by particular variations in the flow of spatially unstructured light over time, it must be assumed that the systems responsible are essentially temporal in character and capable of representing a variety of visual forms and colors, coded in different frequencies or at different phases of the same processing rhythm. (shrink)

This is an excellent book about a variety of themes in seventeenth-century philosophy. Unlike books that try to do too much and succeed at little, this one claims to do a single thing but accomplishes much more than that. Jolley sets out to explore various views about ideas, primarily in the work of Descartes, Malebranche, and Leibniz, but also in others, such as Locke and Arnauld. He does so by examining the contexts in which the "way of ideas" occurs, from (...) innateness to causality to religious issues, in a variety of debates and encounters between these various philosophers. The result is not a comprehensive treatment of the doctrine of ideas in the seventeenth century; figures such as Hobbes and Spinoza are largely excluded and the treatment of Locke and others is very selective. But Jolley does provide something extremely valuable: an engaging and stimulating tour of a series of fascinating philosophical debates which constitute central dimensions of the seventeenth-century philosophical tradition. (shrink)

In this sweeping revision of avant-garde history, John Cage takes his rightful place as Wordsworth's great and final heir. George Leonard traces a direct line back from Cage, Pop, and Conceptual Art through the Futurists to Whitman, Emerson, Ruskin, Carlyle, and Wordsworth, showing how the art of everyday objects, often thought an exclusively contemporary phenomenon, actually began as far back as 1800. In recovering the links between such seemingly disparate figures, Leonard transforms our understanding of modern culture. Selected by the (...) American Library Association's journal, _Choice_, as "one of the Outstanding Academic Books of the Year" "Leonard's book is a fine example of interdisciplinary studies. He shifts focus persuasively from art theory to literature to religious thought and biography, making his method seem the natural mode of inquiry into culture."—Kenneth Baker, _San Francisco Chronicle Book Review_ "Provocative and illuminating."—_Library Journal_ "Highly stimulating, impassioned."—_Publisher's Weekly_ "A rich and rewarding study written in a clear and accessible style with excellent references and a very useful index. Highly recommended."—_Choice_. (shrink)

The centrality of trust in traditional doctor–patient relationships has been criticized as inordinately paternalistic, yet in today's discussions about medical ethics—mostly in response to disruptive innovation in healthcare—trust reappears as an asset to enable empowerment. To turn away from paternalistic trust‐based doctor–patient relationships and to arrive at an empowerment‐based medical model, increasing reference is made to the importance of nurturing trust in technologies that are supposed to bring that empowerment. In this article we stimulate discussion about why the move towards (...) patient empowerment may not be able to keep clear of the criticism of trust in traditional patient–doctor relationships. First, we explore how such a shift in trust dynamics might corrode patient empowerment in the name of patient empowerment. Second, we examine how a translocation of trust may at best push the “trust issue” elsewhere and at worst make it harder to evaluate trustworthiness. (shrink)

The role of augustine for wittgenstein's life and thought has not yet been sufficiently explored. it can throw important light on his personality and on his philosophizing. augustine's impact on wittgenstein's religious life begins during his imprisonment at monte cassino at the end of world war i, but is not reflected in his own writings. in his philosophical texts thus far published references to the "confessions" are traced after "tractatus" in fourteen passages, exceeding those to all other philosophers. a (...) study of these quotations in their contexts shows that they serve not only as inspiration and confirmation but very often as targets for the development of wittgenstein's own thinking. (shrink)

Very few studies are available to understand the philosophical views of Rabindranath Tagore in the light of his attitude and realization of Islam vis-à-vis idea of universalism. Fact remains that the Islamic civilization has thoroughly been recognized in the academic circles but its depth and learning have not been studied up to expectation. European historians and philosophers seem to be hesitant to acknowledge the contribution of Islamic civilization over the centuries. Even a majority of Eastern scholars are critical about (...) welcoming the actual merit of Islam. Rabindranath Tagore being one of the brightest stars in the galaxy of poets and writers made a serious study on the philosophy and writings of many Muslim thinkers and ultimately brought to our notice an extraordinary feeling about Islamic ideas and philosophy. Rabindranth Tagore seems to have sought the inner meaning of Islam and developed a kind of value- based attitude towards human life and the universe. It is likely that through his Gitanjali and Religion of Man in particular were presented with an objective to stimulate and guide men in search of Ultimate Truth and Oneness of God. It is said that Rabindranth Tagore was acquainted with the verses of the Qur‟an in his childhood and in this respect his father Maharishi Devendranath Tagore imbibed in him many theological aspects of Islam as a religion. The paper intends to explore how Tagore was influenced by Islam and as a poet-thinker he nurtured the idea of eternal truth from the Upanishads, the Tripitakas as well as the Bible and through a particular discipline and inner uplift he came to the conclusion that aggregate of essentials of diversity cannot be judged in the light of mere logic and arguments. This feeling seems to have prompted Tagore to find out the inner truth of the universe and side by side to propagate the idea of universal humanism throughout the world. Philosophy and Progress, Vol#61-62; No#1-2; Jan-Dec 2017 P 53-66. (shrink)

The pupils of the eyes reflexively constrict in light and dilate in dark to optimize retinal illumination. Non-visual cognitive factors, like attention, arousal, decision-making, etc., also influence pupillary light response. During passive viewing, the eccentricity of a stimulus modulates the pupillary aperture size driven by spatially weighted corneal flux density, which is the product of luminance and the area of the stimulus. Whether the scope of attention also influences PLR remains unclear. In this study, we contrasted the pupil (...) dynamics between diffused and focused attentional conditions during decision-making, while the global CFD remained the same in the two conditions. A population of 20 healthy humans participated in a pair of forced choice tasks. They distributed attention to the peripheral decision cue in one task, and concentrated at the center in the other to select the target from four alternatives for gaze orientation. The location of this cue did not influence participants’ reaction time. However, the magnitude of constriction was significantly less in the task that warranted attention to be deployed at the center than on the periphery. We observed similar pupil dynamics when participants either elicited or canceled a saccadic eye movement, which ruled out pre-saccadic obligatory attentional orientation contributing to PLR. We further addressed how the location of attentional deployment might have influenced PLR. We simulated a biomechanical model of PLR with visual stimulation of different strengths as inputs corresponding to the two attentional conditions. In this homeomorphic model, the computational characteristic of each element was derived from the physiological and/or mechanical properties of the corresponding biological element. The simulation of this model successfully mimicked the observed data. In contrast to common belief that the global ambient luminosity drives pupillary response, the results of our study suggest that the effective CFD determined via the luminance multiplied by the size of the stimulus at the location of deployed attention in the visual space is critical for the magnitude of pupillary constriction. (shrink)

In the past thirty years environmental ethics has emerged as one of the most vibrant and exciting areas of applied philosophy. Several journals and hundreds of books testify to its growing importance inside and outside philosophical circles. But with all of this scholarly output, it is arguably the case that environmental ethics is not living up to its promise of providing a philosophical contribution to the resolution of environmental problems. This article surveys the current state of the field and offers (...) an alternative path for the future development of environmental ethics toward a more publicly engaged model of applied philosophy. (shrink)

The aesthetics of everyday life, originally developed by Henri Lefebvre and other modernist theorists, is an extension of traditional aesthetics, usually confined to works of art. It is not limited to the study of humble objects but is rather concerned with all of the undeniably aesthetic experiences that arise when one contemplates objects or performs acts that are outside the traditional realm of aesthetics. It is concerned with the nature of the relationship between subject and object. One significant aspect of (...) everyday aesthetics is environmental aesthetics, whether constructed, as a building, or manipulated, as a landscape. Others, also discussed in the book, include sport, weather, smell and taste, and food. (shrink)

Institutional corruption is a normative concept of growing importance that embodies the systemic dependencies and informal practices that distort an institution’s societal mission. An extensive range of studies and lawsuits already documents strategies by which pharmaceutical companies hide, ignore, or misrepresent evidence about new drugs; distort the medical literature; and misrepresent products to prescribing physicians. We focus on the consequences for patients: millions of adverse reactions. After defining institutional corruption, we focus on evidence that it lies behind the epidemic of (...) harms and the paucity of benefits. (shrink)

Over the past 35 years, patients have suffered from a largely hidden epidemic of side effects from drugs that usually have few offsetting benefits. The pharmaceutical industry has corrupted the practice of medicine through its influence over what drugs are developed, how they are tested, and how medical knowledge is created. Since 1906, heavy commercial influence has compromised congressional legislation to protect the public from unsafe drugs. The authorization of user fees in 1992 has turned drug companies into the FDA's (...) prime clients, deepening the regulatory and cultural capture of the agency. Industry has demanded shorter average review times and, with less time to thoroughly review evidence, increased hospitalizations and deaths have resulted. Meeting the needs of the drug companies has taken priority over meeting the needs of patients. Unless this corruption of regulatory intent is reversed, the situation will continue to deteriorate. We offer practical suggestions including: separating the funding of clinical trials from their conduct, analysis, and publication; independent FDA leadership; full public funding for all FDA activities; measures to discourage R&D on drugs with few, if any, new clinical benefits; and the creation of a National Drug Safety Board. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Ethics & the Environment 7.1 (2002) 102-108 [Access article in PDF] Symposium IntroductionEric Katz's Nature As Subject Andrew Light Can and should we distinguish between nature and culture? The question has become a perennial one in environmental ethics, as well as in allied fields in environmental history, sociology, and politics. And just when we think it is settled—as many did after William Cronon's famous deconstruction of wilderness in (...) 1995—and it feels safe to go back into the metaphysical waters of environmental philosophy, such issues pop up again to send us running.What follows extends this debate in the context of Eric Katz's well-known work in environmental ethics. Brought together here are Katz and two critics sympathetic to his positions, Wayne Ouderkirk and Ned Hettinger. While the occasion for the exchange was the publication of Katz's book, Nature as Subject: Human Obligation and Natural Community (1997), which collects his papers from 1979 to 1996, the focus quickly became somewhat narrower, centering on possible problems with Katz's ontological dualism between natural and artifactual entities.Katz has exerted a strong influence on the development of environmental ethics, particularly through his persistent arguments for a distinction between individualist and holist approaches to obligations to the nonhuman natural world and his metaphysical and moral critique of attempts [End Page 102] by humans to create, repair, or restore nature. While these positions continue to be on display here, there is also something more. In this exchange Katz throws down the gauntlet on his nature-culture dualism, admitting at the start that the accusation is true. Like the Protestants in Monty Python's The Meaning of Life, he is a dualist—and fiercely proud of it! Despite whatever misgivings I or others may have about this position, I believe that in making this claim, Katz, similar to David Chalmers's open embrace and resuscitation of dualism in philosophy of mind, has done us a great service. For it is arguably true that many environmental philosophers, along with other academics, have settled into a complacent "labeling as argument" pattern. If we can label a position as "dualist" or "essentialist," then our work is done. But surely not every form of dualism is necessarily wrong, even if, as Ouderkirk reminds us in his reading of Val Plumwood's work, the logic of many forms of dualism has tended toward a pernicious pattern. Arguments are needed in both directions. If nature-culture dualism is mistaken or wrongheaded, or leads to unfortunate conclusions, then we must know why; if dualism is the only way to make sense of the hurdles presented to us in coming to a better understanding of the value of nature and culture then we must know why as well. And further, because many in the field have assumed a nature-culture dualism without admitting to it, we can admire that Katz chooses to "fess up" and finally put the issue squarely on the table.If this is the road we are heading down with this particular exchange, then we are off to a good start. Both critics of Katz do a thorough job of pressing home their arguments, rather than only pointing accusatory fingers. Ned Hettinger, in "The Problem of Finding a Positive Role for Humans in the Natural World," avoids using the term "dualism," but nonetheless argues that Katz has a tendency to "rigidly dichotomize the natural/artifactual distinction." Additionally, Hettinger argues that Katz tends to overlook his own admission that the differences between nature and artifacts admit to degrees rather than a strict dualism. Hettinger focuses the bulk of his critique on the unfortunate upshot of such a position: given such a distinction, there is little if any place for a positive role for human intervention in nature, or for a philosophical contribution to the formation of better environmental policies.Wayne Ouderkirk, in "Katz's Problematic Dualism and its 'Seismic' Effects on His Theory," is sympathetic with Katz's intuitions that some distinction is needed between artifacts and natural entities. The problem [End Page 103] he sees is that such... (shrink)

_ _ _Environmental Ethics: An Anthology_ brings together both classic and cutting-edge essays which have formed contemporary environmental ethics, ranging from the welfare of animals versus ecosystems to theories of the intrinsic value of nature.

There are many ways to describe cities. As a physical environment, more so than many other environments, they are at least an extension of our present intentions. But cities are not confined to the moment. Built spaces are also in conversation with the past and oriented toward the future as physical manifestations of our values and priorities. But even with all of the ways we have to describe cities we do not normally think of them as in any way akin (...) to the “natural” environment. City and country, nature and culture, are opposed. We move through cities differently, with a different set of values, whether articulated or not. Consider just one small example: Even the most jaded urban dweller may hesitate to sully the environment around him when he perceives it to be something other than a product of the human community. Though we have all seen trash in a national park, we suspect (or at least hope) that there is a kind of hesitancy that occurs with a person wondering what to do with her candy wrappers on a trail in Yosemite. On the other hand, a visitor to my home, Greenwich Village, will usually not think twice about tossing his cigarette butts on the ground as he walks toward his next destination. (shrink)