14 found
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  1.  21
    Ethics Education for Healthcare Professionals in the Era of ChatGPT and Other Large Language Models: Do We Still Need It?Vasiliki Rahimzadeh, Kristin Kostick-Quenet, Jennifer Blumenthal Barby & Amy L. McGuire - 2023 - American Journal of Bioethics 23 (10):17-27.
    ChatGPT has taken the academic community by storm (Cotton, Cotton, and Shipway 2023; Cox and Tzoc 2023; Sullivan, Kelly, and McLaughlan 2023). Since its release in November 2022, chatGPT has predic...
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  2.  36
    Mitigating Racial Bias in Machine Learning.Kristin M. Kostick-Quenet, I. Glenn Cohen, Sara Gerke, Bernard Lo, James Antaki, Faezah Movahedi, Hasna Njah, Lauren Schoen, Jerry E. Estep & J. S. Blumenthal-Barby - 2022 - Journal of Law, Medicine and Ethics 50 (1):92-100.
    When applied in the health sector, AI-based applications raise not only ethical but legal and safety concerns, where algorithms trained on data from majority populations can generate less accurate or reliable results for minorities and other disadvantaged groups.
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  3.  31
    Researcher Views on Changes in Personality, Mood, and Behavior in Next-Generation Deep Brain Stimulation.Peter Zuk, Clarissa E. Sanchez, Kristin Kostick-Quenet, Katrina A. Muñoz, Lavina Kalwani, Richa Lavingia, Laura Torgerson, Demetrio Sierra-Mercado, Jill O. Robinson, Stacey Pereira, Simon Outram, Barbara A. Koenig, Amy L. McGuire & Gabriel Lázaro-Muñoz - 2023 - American Journal of Bioethics Neuroscience 14 (3):287-299.
    The literature on deep brain stimulation (DBS) and adaptive DBS (aDBS) raises concerns that these technologies may affect personality, mood, and behavior. We conducted semi-structured interviews with researchers (n = 23) involved in developing next-generation DBS systems, exploring their perspectives on ethics and policy topics including whether DBS/aDBS can cause such changes. The majority of researchers reported being aware of personality, mood, or behavioral (PMB) changes in recipients of DBS/aDBS. Researchers offered varying estimates of the frequency of PMB changes. A (...)
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  4.  18
    Research on the Clinical Translation of Health Care Machine Learning: Ethicists Experiences on Lessons Learned.Jennifer Blumenthal-Barby, Benjamin Lang, Natalie Dorfman, Holland Kaplan, William B. Hooper & Kristin Kostick-Quenet - 2022 - American Journal of Bioethics 22 (5):1-3.
    The application of machine learning in health care holds great promise for improving care. Indeed, our own team is collaborating with experts in machine learning and statistical modeling to bu...
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  5.  33
    Perspectives on informed assent and bodily integrity in prospective deep brain stimulation for youth with refractory obsessive-compulsive disorder.Jared N. Smith, Natalie Dorfman, Meghan Hurley, Ilona Cenolli, Kristin Kostick-Quenet, Gabriel Lazaro-Munoz, Eric A. Storch & Jennifer Blumenthal-Barby - forthcoming - Clinical Ethics.
    BackgroundDeep brain stimulation is approved for treating refractory obsessive-compulsive disorder in adults under the US Food and Drug Administration Humanitarian Device Exemption, and studies hav...
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  6.  8
    Computational Ethics Tools to Audit Corporate Self-Governance in Data Processing.Christine R. Deeney & Kristin Kostick-Quenet - 2023 - American Journal of Bioethics 23 (11):42-44.
    Frameworks for responsible data stewardship, such as that proposed by McCoy et al. (2023), are intended to encourage and provide guidelines for data processors to engage in responsible data process...
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  7.  31
    Trust criteria for artificial intelligence in health: normative and epistemic considerations.Kristin Kostick-Quenet, Benjamin H. Lang, Jared Smith, Meghan Hurley & Jennifer Blumenthal-Barby - forthcoming - Journal of Medical Ethics.
    Rapid advancements in artificial intelligence and machine learning (AI/ML) in healthcare raise pressing questions about how much users should trust AI/ML systems, particularly for high stakes clinical decision-making. Ensuring that user trust is properly calibrated to a tool’s computational capacities and limitations has both practical and ethical implications, given that overtrust or undertrust can influence over-reliance or under-reliance on algorithmic tools, with significant implications for patient safety and health outcomes. It is, thus, important to better understand how variability in trust (...)
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  8.  16
    Adolescent OCD Patient and Caregiver Perspectives on Identity, Authenticity, and Normalcy in Potential Deep Brain Stimulation Treatment.Jared N. Smith, Natalie Dorfman, Meghan Hurley, Ilona Cenolli, Kristin Kostick-Quenet, Eric A. Storch, Gabriel Lázaro-Muñoz & Jennifer Blumenthal-Barby - forthcoming - Cambridge Quarterly of Healthcare Ethics:1-14.
    The ongoing debate within neuroethics concerning the degree to which neuromodulation such as deep brain stimulation (DBS) changes the personality, identity, and agency (PIA) of patients has paid relatively little attention to the perspectives of prospective patients. Even less attention has been given to pediatric populations. To understand patients’ views about identity changes due to DBS in obsessive-compulsive disorder (OCD), the authors conducted and analyzed semistructured interviews with adolescent patients with OCD and their parents/caregivers. Patients were asked about projected impacts (...)
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  9.  10
    Personalized Roadmaps for Returning Results From Digital Phenotyping.Kristin Marie Kostick-Quenet, John Herrington & Eric A. Storch - 2024 - American Journal of Bioethics 24 (2):102-105.
    While the intellectual challenge of digital phenotyping (DP) has evolved from data collection to more complex data analysis (Onnela 2021), core ethical considerations remain centered on patient pri...
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  10.  24
    Hope and Optimism in Pediatric Deep Brain Stimulation: Key Stakeholder Perspectives.Natalie Dorfman, Lilly Snellman, Ynez Kerley, Kristin Kostick-Quenet, Gabriel Lazaro-Munoz, Eric A. Storch & Jennifer Blumenthal-Barby - 2023 - Neuroethics 16 (3):1-15.
    IntroductionDeep brain stimulation (DBS) is utilized to treat pediatric refractory dystonia and its use in pediatric patients is expected to grow. One important question concerns the impact of hope and unrealistic optimism on decision-making, especially in “last resort” intervention scenarios such as DBS for refractory conditions.ObjectiveThis study examined stakeholder experiences and perspectives on hope and unrealistic optimism in the context of decision-making about DBS for childhood dystonia and provides insights for clinicians seeking to implement effective communication strategies.Materials and MethodsSemi-structured interviews (...)
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  11.  15
    Integrating Social Determinants of Health into Ethical Digital Simulations.Kristin Kostick-Quenet, Vasiliki Rahimzadeh, Sharmila Anandasabapathy, Meghan Hurley, Anika Sonig & Amy Mcguire - 2023 - American Journal of Bioethics 23 (9):57-60.
    In their article, Cho and Martinez-Martin (2023) argue that developers and users of digital simulacra for modelling health and disease should involve a continued focus on causality of health states...
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  12.  12
    A Call for Behavioral Science in Embedded Bioethics.Kristin M. Kostick-Quenet, Benjamin Lang, Natalie Dorfman & J. S. Blumenthal-Barby - 2022 - Perspectives in Biology and Medicine 65 (4):672-679.
    ABSTRACT:Bioethicists today are taking a greater role in the design and implementation of emerging technologies by "embedding" within the development teams and providing their direct guidance and recommendations. Ideally, these collaborations allow ethical considerations to be addressed in an active, iterative, and ongoing process through regular exchanges between ethicists and members of the technological development team. This article discusses a challenge to this embedded ethics approach—namely, that bioethical guidance, even if embraced by the development team in theory, is not easily (...)
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  13.  20
    Researchers’ Ethical Concerns About Using Adaptive Deep Brain Stimulation for Enhancement.Kristin Kostick-Quenet, Lavina Kalwani, Barbara Koenig, Laura Torgerson, Clarissa Sanchez, Katrina Munoz, Rebecca L. Hsu, Demetrio Sierra-Mercado, Jill Oliver Robinson, Simon Outram, Stacey Pereira, Amy McGuire, Peter Zuk & Gabriel Lazaro-Munoz - 2022 - Frontiers in Human Neuroscience 16.
    The capacity of next-generation closed-loop or adaptive deep brain stimulation devices to read and write shows great potential to effectively manage movement, seizure, and psychiatric disorders, and also raises the possibility of using aDBS to electively modulate mood, cognition, and prosociality. What separates aDBS from most neurotechnologies currently used for enhancement is that aDBS remains an invasive, surgically-implanted technology with a risk-benefit ratio significantly different when applied to diseased versus non-diseased individuals. Despite a large discourse about the ethics of enhancement, (...)
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  14.  22
    Capacities and Limitations of Using Polygenic Risk Scores for Reproductive Decision Making.Gabriel Lázaro-Muñoz, Stacey Pereira, Meghna Mukherjee, Kristin Marie Kostick-Quenet, Shai Carmi, Todd Lencz & Dorit Barlevy - 2022 - American Journal of Bioethics 22 (2):42-45.
    In their article “Implementing Expanded Prenatal Genetic Testing: Should Parents Have Access to Any and All Fetal Genetic Information?” Bayefsky and Berkman briefly mention that: “[s]ome are...
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