The treatise On Formative Power of Ferrara's emblematic medical humanist, Nicolò Leoniceno , is the one of the first embryological monographs of the Renaissance. It shows, at the same time, the continuity of medieval Arabo-Latin tradition and the new elements brought by Renaissance medical humanism, namely through the use of the ancient Greek commentators of Aristotle like Simplicius. Thus this treatise stands at the crossroad of these two currents. The present study analyses the range of Leoniceno's philosophical discussion, (...) determines its exact sources and brings to light premises for the early modern development of the concept of formative force, which will end up in the theory of "plastic nature" at the heart of the Scientific Revolution. (shrink)

This volume deals with philosophically grounded theories of animal generation as found in two different traditions: one, deriving primarily from Aristotelian natural philosophy and specifically from his Generation of Animals; and another, deriving from two related medical traditions, the Hippocratic and the Galenic. The book contains a classification and critique of works that touch on the history of embryology and animal generation written before 1980. It also contains translations of key sections of the works on which it is focused. (...) It looks at two different scholarly communities: the physicians and philosophers, that share a set of textual resources and philosophical lineages, as well as a shared problem, but that nevertheless have different concerns and commitments. The book demonstrates how those working in these two traditions not only shared a common philosophical background in the arts curricula of the universities, but were in constant intercourse with each other. This book presents a test case of how scholarly communities differentiate themselves from each other through methods of argument, empirical investigation, and textual interpretations. It is all the more interesting because the two communities under investigation have so much in common and yet, in the end, are distinct in a number of important ways. (shrink)

In his embryological treatise De plastica seminis facultate , Jacob Schegk , professor of philosophy and medicine at the University of Tübingen, developed, through a unique interpretation of the Aristotelian embryology, a theory of the "plastic faculty" , whose origin lay in the Galenic idea of the formative power. The present study analyses the precise nature of Schegk's theory, by setting it in its historical and intellectual context. It will also discuss the hitherto unappreciated Neoplatonic dimension of Schegk's notion (...) of the soul's vehicle. (shrink)

What does Descartes's embryology look, if related to the Scholastic theories of his time? In order to reply to this question, the present chapter aims at sketching a portrait of the embryological epigenetics Descartes could find in his recognized Scholastic sources (the Commentaries on Aristotle by Toledo, the Coimbra Jesuits, Suárez, and Rubio, as well as the Summae by Eustachius a Sancto Paulo and Abra de Raçonis), a tradition that received and incorporated in the Aristotelian-Galenic body many novelties from (...) Renaissance medicine, especially Fernel, Paré, and Vallès. It being impossible to deal extensively with the whole of the contents of these works, I picked up three issues in particular, corresponding to the first three paragraphs of this paper: 1) the nature of the semen, and the action of the vis formativa, as well as its relationship with vital heat and temperaments; 2) the problem of the real and/or rational distinction(s) between the generative, the nutritive, and the augmentative powers; 3) the epigenetic order of generation of vital organs, i.e. the right sequence over which the fundamental organs of a living body are generated and then ensouled. In the last paragraph I integrate these reconstructions with some conclusions about Descartes' own theory. (shrink)

From the sixteenth to the eighteenth century, new anatomical investigations of the brain and the nervous system, together with a renewed interest in comparative anatomy, allowed doctors and philosophers to ground their theories on sense perception, the emergence of human intelligence, and the soul/body relationship in modern science. They investigated the anatomical structures and the physiological processes underlying the rise, differentiation, and articulation of human cognitive activities, and looked for the “anatomical roots” of the specificity of human intelligence when compared (...) to other forms of animal sensibility. This edited volume focuses on medical and philosophical debates on human intelligence and animal perception in the early modern age, providing fresh insights into the influence of medical discourse on the rise of modern philosophical anthropology. Contributions from distinguished historians of philosophy and medicine focus on sixteenth-century zoological, psychological, and embryological discourses on man; the impact of mechanism and comparative anatomy on philosophical conceptions of body and soul; and the key status of sensibility in the medical and philosophical enlightenment. (shrink)

The treatise On Formative Power of Ferrara's emblematic medical humanist, Nicolò Leoniceno, is the one of the first embryological monographs of the Renaissance. It shows, at the same time, the continuity of medieval Arabo-Latin tradition and the new elements brought by Renaissance medical humanism, namely through the use of the ancient Greek commentators of Aristotle like Simplicius. Thus this treatise stands at the crossroad of these two currents. The present study analyses the range of Leoniceno's philosophical discussion, determines (...) its exact sources and brings to light premises for the early modern development of the concept of formative force, which will end up in the theory of "plastic nature" at the heart of the Scientific Revolution. (shrink)

Historically, philosophers of biology have tended to sidestep the problem of development by focusing primarily on evolutionary biology and, more recently, on molecular biology and genetics. Quite often too, development has been misunderstood as simply, or even primarily, a matter of gene activation and regulation. Nowadays a growing number of philosophers of science are focusing their analyses on the complexities of development, and in Embryology, Epigenesis and Evolution Jason Scott Robert explores the nature of development against current trends in (...) biological theory and practice and looks at the interrelations between development and evolution, an area of resurgent biological interest. Clearly written, this book should be of interest to students and professionals in the philosophy of science and the philosophy of biology. (shrink)

Historically embryogenesis has been among the most philosophically intriguing phenomena. In this paper I focus on one aspect of biological development that was particularly perplexing to the ancients: self-organisation. For many ancients, the fact that an organism determines the important features of its own development required a special model for understanding how this was possible. This was especially true for Aristotle, Alexander, and Simplicius, who all looked to contemporary technology to supply that model. However, they did not all agree on (...) what kind of device should be used. In this paper I explore the way these ancients made use of technology as a model for the developing embryo. I argue that their different choices of device reveal fundamental differences in the way each thinker understood the nature of biological development itself. In the final section of the paper I challenge the traditional view (dating back to Alexander's interpretation of Aristotle) that the use of automata in GA can simply be read off from their use in the de motu. (shrink)

The extent of the dependence of early Greek cosmogony on mythical conceptions has long been a prolific source of controversy. Views on the subject have varied from Professor Cornford's claim that ‘there is a real continuity between the earliest rational speculation and the religious representation that lay behind it’ to Professor Burnet's extreme statement, ‘it is quite wrong to look for the origins of Ionian science in mythological ideas of any kind.’ The solution of the problem that I wish to (...) suggest is one which should satisfy those who insist on ‘the scientific character of the early Greek cosmology,’ while retaining a direct connection with pre-scientific beliefs—namely, that some, at least, of the earliest philosophers founded their doctrines of the beginning of the universe on a deliberate rationalization of earlier and contemporary mythical ideas. The appearance of notions like the ‘world-egg’ in a number of passages, too well known for quotation, shows that primitive cosmogony assumed an analogy between the generation of the world and the generation of animate creatures. I believe it can be proved that, so far from the ‘renunciation of sexual imagery’ which even Professor Cornford has recently attributed to Anaximander, he and other philosophers retained the habit of regarding cosmogony and anthropogony as parallel phenomena, only substituting for the mythical ‘world-egg’ a more scientific view of the embryo and its development. They looked at the world through the same spectacles as their predecessors, but after wiping from them the rose tint of mythological fancy. (shrink)

During the early part of the 20th century most embryologists were skeptical about the significance of Mendelian genetics to embryological development. A few embryologists began to study the developmental effects of Mendelian genes around 1940. Such work was a necessary step on the path to modern developmental biology. It occurred during the time when the Evolutionary Synthesis was integrating Mendelian and population genetics into a unified evolutionary theory. Why did the first embryological geneticists begin their study at that particular time? (...) One possible explanation is that developmental genetics was a potential avenue of alliance between embryology and evolutionary biology, two fields that had been separated since the 1890s. To assess this possible motive it is necessary to explore the methodological contrasts that obtained between embryology and both Mendelian-chromosomal genetics and neo-Darwinian evolutionary theory. Some of these contrasts persist to the present day. (shrink)

The Renaissance was a period of great intellectual change and innovation as philosophers rediscovered the philosophy of classical antiquity and passed it on to the modern age. Renaissance philosophy is distinct both from the medieval scholasticism, based on revelation and authority, and from philosophers of the seventeenth and eighteenth centuries who transformed it into new philosophical systems. Despite the importance of the Renaissance to the development of philosophy over time, it has remained largely understudied by historians of (...) philosophy and professional philosophers. This anthology aims to correct this by providing scholars and students of philosophy with representative translations of the most important philosophers of the Renaissance. Its purpose is to help readers appreciate philosophy in the Renaissance and its importance in the history of philosophy. The anthology includes translations from philosophers from the thirteenth to the seventeenth centuries, and it ranges from works on moral and political philosophy, to metaphysics, epistemology, and natural philosophy, thereby providing historians and students of philosophy with a sense for the nature, breadth, and complexity of philosophy in the Renaissance. Each translation is accompanied by an introduction by a historian of Renaissance philosophy, as well as select secondary sources, in order to encourage further study. (shrink)

Over the last several decades many abortion advocates have attempted to spread confusion and doubt concerning the beginnings of human life. A particularly cynical strategy has involved invoking the authority historical thinkers, especially Doctors of the Church, to support the claim that (at least) early abortion does not constitute homicide because the early embryo is not yet fully human. Anyone familiar with context of these historical thinkers should realize that their specific judgments regarding abortion are now obsolete in virtue of (...) their primitive scientific understanding of embryology. In what follows, I summarize the Aristotelian embryology that explains why these historical thinkers held the views that they did. I then explore how we should best understand their broader ethical views in light of our vastly superior contemporary knowledge of human embryology. Unsurprisingly, it turns out that if we apply the contemporary empirical findings of embryology the very same metaphysical and ethical principles informing the thinking of the historical figures supports the prolife position. (shrink)

In this paper I have not, of course, presented all the embryological data that can be collected from the Talmudic and Midrashic literature. More details can be found in Julius Preuss' classical work on biblical and talmudic medicine, now available in Fred Rosner's English translation and in a French M.D. thesis by Martine Michel.75 I also did not present any data on teratology, and did not deal with the very rich Jewish mystical lore, the Cabbala. But a few comments are (...) in order here about the material on embryology.There are very few original ideas in the Talmudic corpus on embryology, but it is obvious that the Sages were well aware of the Greek and Roman theories on embryology.The fact that the Talmud is a compilation that was built up slowly, during several centuries, explains why the information recorded in it cannot be ascribed solely to one school of thought or one clear-cut influence.When a definite problem was difficult to solve because there were many different theories about it, the Sages based their opinion on a famous experiment that seemed to offer guarantees of validity. This was the case with the controversial problem of the formation of the embryo and its sexual differentiation, where the Sages made use of an experiment allegedly initiated by Cleopatra.The Sages were ready to discuss scientific problems with non-Jewish scholars and even to accept their arguments. This was the case with the important topic of the time of the entry of the soul into the embryo. But the legal conclusions drawn from the Sages' opinion were not consistent with those declared by Churth Fathers such as Tertullian. Embryotomy, for instance, was permitted by Jewish law.Wide interest, scholarly discussions, suggestive descriptions and readiness to inquire and to obtain detailed information characterized the Talmudic discussions of embryology.In conclusion, I quote a Talmudic text that reviews the whole process of embryological development through the sequence of prayers of a faithful Jew who learns that his wife is expecting a baby.The first three days, [he should pray to the Lord] that the seed should not putrefy.From the third to the fortieth day: that the child should be a male.From the fortieth day to the third month: that there should not occur any superfetation, which could lead the first embryo to be a fetus compressus.From the third to the sixth month: that an abortion should not occur.From the sixth to the ninth month: that the birth should be without problems.76. (shrink)

The Renaissance has long been recognized as a brilliant moment in the development of Western civilization. Little attention has been devoted, however, to the distinct contribution of philosophy to Renaissance culture. This volume introduces the reader to the philosophy written, read, taught, and debated during the period traditionally credited with the "revival of learning." Beginning with original sources still largely inaccessible to most readers, and drawing on a wide range of secondary studies, the author examines the relation of (...) Renaissance philosophy to humanism and the universities, the impact of rediscovered ancient sources, the recovery of Plato and the Neoplatonists, and the evolving ascendancy of Aristotle. Renaissance Philosophy also explores the original contributions of major figures including Bruni, Valla, Ficino, Pico della Mirandola, Pomponazzi, Machiavelli, More, Vitoria, Montaigne, Bruno, and Camapanella. (shrink)

In a poem setting forth the way things are in nature, it is fitting for Lucretius to address, among many other phenomena, human conception and embryonic determination. With an eye toward ethics, Lucretius demonstrates how sexual reproduction at the seminal level can be explained by Epicurean atomism. In this paper, I am concerned with the biological ‘how’ of conception as explained inDe Rerum Natura(=DRN) but also with the ethical ‘therefore’ for Lucretius’ readership and (over)estimations of male autonomy. For modern audiences (...) with a basic grasp of procreation that includes sperm supplied by a male and egg supplied by a female, encountering Lucretius’ verses on women contributing semen (semina) to the process of conception can be surprising (4.1209–62). The idea of female semen may give us pause as we calibrate it with our understanding of eggs and ovulation, but Lucretius, in his time, was not advancing some novel theory. Wading into established debates on male-only or joint male-female semen production and gendered insemination (that is, who produces semen and whose semen is active at conception), Lucretius sides with those promulgating mutuality for both questions (for example Democritus [DK 24 A13]) and rejects Aristotle's representative exclusivist claim of male activity vs female passivity (τὸ ἄρρεν ἐστὶν ὡς κινοῦν καὶ ποιοῦν, τὸ δὲ θῆλυ ὡς παθητικόν,Gen. an.729a28–30; cf. 726a30–6). That is to say, a sexually mature female, like her male counterpart, emits semen that has determining potency in the formation of a human embryo (Lucr. 4.1209–62). Although the discharge and activity of female semen is the focus of this paper, my investigation is not aQuellenforschungor historical survey of Greco-Roman ideas about women's contributions to insemination and fertility, since others have treated these matters extensively. I concentrate rather on how Lucretius employs the concept of female semen in terms of his poetics in Book 4 and what I see as an ethical argument against the domineering nature of Roman masculinity. The problem of female semen, from the point of view of Lucretius’ Roman male audience, is that it is potentially costly to men because it rivals and threatens their status from the physiological to the discursive level. Iain Lonie broaches the same issue from Greek perspectives. (shrink)

Ackrill’s Problem is a tension between Aristotle’s alleged view that the matter of a living being is a body that is essentially ensouled, and his view that the matter of a substance preexists its generation. Most interpreters solve the tension by claiming that the subject of substantial generation is not the organic body of the living being, but its non-organic matter. I defend a different solution by showing that the embryological theory ofOn the Generation of Animalsimplies that the organic body (...) of a living being already exists before acquiring the soul in actuality. (shrink)

The Human Fertilisation and Embryology Act 2008: a missed opportunity?Amel AlghraniCorrespondence to Dr Amel Alghrani, Institute for Science, Ethics and Innovation, Centre for Social Ethics and Policy, School of Law, University of Manchester, Oxford Road, Manchester, M13 9PL; [email protected] 16 September 2009 Accepted 24 September 2009 Regulating reproduction is no easy feat. In the past three decades we have witnessed a reproductive revolution and great strides have been made to alleviate the effects of infertility. Reproductive advances such as in-vitro (...) fertilisation , sex selection, reproductive cloning and embryo selection for the purpose of creating “saviour siblings” have all emerged as part of a rapid and ever-changing branch of medicine, each promising to upset the status quo and transform human reproduction.Following much activity in this area, the lengthy process of updating the legislation is now complete. The Human Fertilisation and Embryology Act 2008 received Royal Assent on 13 November 2008. The majority of the HFE Act 2008’s amendments will come into force in October of this year, with the exception of the provisions pertaining to parenthood, which commenced in April 2009. Welcoming Royal Assent, Professor Lisa Jardine, Chair of the Human Fertilisation and Embryology Authority, stated:“This is a momentous day for the HFEA and for those with fertility problems. The regulatory system that has served us so well has been renewed. Parliament has provided a clear framework for the future and a solid base on which to regulate 21st century practice within 21st century law.”1However, as scientific endeavours into developments such as artificial gametes, womb transplantation and ectogenesis continue apace, it could be argued that Jardine was perhaps overly optimistic about the achievements of the new legislation. The HFE Act 2008 is an amending statute, and as Jackson 2 notes “much of the regulatory architecture” in the 1990 legislation “remains intact”. In retaining the architecture of the 1990 legislation, and merely amending or adding certain provisions, has the government missed an ideal opportunity to consider how to equip the regulatory framework for the next phase/era of assisted reproduction?The next …. (shrink)

Renaissance magic was an attempt to supply Platonism with a philosophy of nature that could compete with Aristotelian physics. It was expected to heal the increasing breach between science and faith. However, the basic presupposition of every magic worldview, the notion of a living universe, favors immanentism and arguably hastened the rise of secularism. Secularism, it should be noted, was not an identifiable set of theories but a process towards modernity with its correspondent philosophical theology. Three different stages in (...) that development can be shown in the philosophical systems of three famous Renaissance magicians: Henry Cornelius Agrippa, Giordano Bruno, and Tommaso Campanella. (shrink)

An eleventh-century manuscript in the Biblioteca Laurenziana in Florence preserves a short excerpt of a calendar outlining stages in the development of the foetus. It is headed Δαμναστού έκ τού Περί κυουσών καί βρεΦών θεραπείας, ‘Damnastes, from On the Care of Pregnant Women and of Infants’. Though its existence has long been noted, it has not been previously edited or published.

In 2006, based on the advice of 50 international experts, the Lawson Wilkins Pediatric Endocrine Society and the European Society for Paediatric Endocrinology issued a consensus statement on the nomenclature and management of children who have a phenotype that is neither typical male nor female (Lee et al. 2006). Responding to a decade of criticism over the terminology that had been in place, including such terms as intersex, hermaphrodite, or pseudohermaphrodite, they proposed to call those conditions in which the patient (...) does not have the typical male or female gonads, chromosomes, or anatomy "disorders of sexual development."While this proposed change in nomenclature is helpful, in order to truly effect a .. (shrink)

Francesco Petrarca, translated by H. Nachod: Introduction. A self-portrait. The ascent of Mont Ventoux. On his own ignorance and that of many others. A disapproval of an unreasonable use of the discipline of dialectic. An Averroist visits Petrarca. Petraca's aversion to Arab science. A request to take up the fight against Averroes.--Lorenzo Valla, translated by C.E. Trinkaus, Jr.: Introduction by C.E. Trinkaus, Jr. Dialogue on free will.--Marsilio Ficino, translated by J.L. Burroughs: Introduction, by J.L. Burroughs. Five questions concerning the mind.-- (...) Giovanni Pico della Mirandola, translated by E.L. Forbes Introduction, by P.O. Kristeller. Oration on the dignity of man.--Pietro Pomponazzi, translated by W.H. Hay. Introduction, by J.H. Randall. On the immortality of the soul.--Juan Luis Vives, translated by N. Lenkeith: Introduction, by N. Lenkeith. A fable about man.--Selective bibliography (p. 397-400). (shrink)

In this paper we examine the study of minerals from the Renaissance to the early nineteenth century in the light of the work of Michel Foucault on the history of systems of thought. In spite of a certain number of theoretical problems, Foucault's enterprise opens up to the historian of science a vast terrain for exploration. But this is the place neither for a general exegesis nor for a general criticism of his position; our aim here is the more (...) modest one of taking certain points from Foucault's study,The order of things, and seeing how far they can be extended into an area not explicitly considered in that work. (shrink)

The problem of generation has been, for Kant scholars, a kind of test of Kant's successive concepts of finality. Although he deplores the absence of a naturalistic account of purposiveness (and hence of reproduction) in his pre-critical writings, in the First Critique he nevertheless presents a "reductionist" view of finality in the Transcendental Dialectic's Appendices. This finality can be used only as a language, extended to the whole of nature, but which must be filled with mechanistic explanations. Therefore, in 1781, (...) mechanism and teleology are synonymous languages. Despite the differences between its two authors, the Wolffian embryology, exposed in the Theorie der Generation (1764), and debated by Blumenbach's dissertation on Bildungstrieb, enabled Kant to resolve the philosophical problem of natural generation, and subsequently to determine what is proper to the explanation of living processes. Thus, in the Third Critique he could give another account of purposiveness, restricted to the organism, and more realistic than his former one; this philosophical reappraisal of purposiveness in embryology required the new concept of "simply reflexive judgement", and the correlated notion of "regulative principle". Thus framed, this naturalized teleology provided some answers to the Kantian problem of order and contingency after the end of classical (Leibnizian) metaphysics. (shrink)

"Plato in the Italian Renaissance, the first book-length treatment of Renaissance Platonism in over fifty years, is a study of the dramatic revival of interest in the Platonic dialogues in Italy in the fifteenth century. Through a richly contextual study of the translations and commentaries on Plato, James Hankins seeks to show how the interpretation of Plato was molded by the expectations of fifteenth-century readers, by the need to protect Plato against his critics, and the broader hermeneutical assumptions (...) and practices of the period. (shrink)