In a series of writings in recent years, Anthony Giddens has pursued two broad interconnected themes: reflection on the future of radical politics in a world in which, it is claimed, received political ideologies of Right and Left are exhausted; and, analysis of the character of what Giddens calls ‘second-phase’ modernisation. The connection between the two themes is straightforward: it is because the world has changed in profound ways that radical politics cannot be continued in the old way. Both of (...) these themes are analysed at length in Beyond Left and Right. In this work, Giddens describes a long-run shift in our relationship to social and technological change manifest in the advance of ‘manufactured uncertainty’ or risk. This has been accelerated by a shift from ‘simple’ to 'reflexive’ modernisation which is a compound of a related series of developments during the post-war period – the ‘social revolutions of our time’. (shrink)

The ArgumentIn this paper I challenge the “uncertainty reduction” argument — the dominant explanation for the rise of bureaucratic firms in the late nineteenth century. In contradiction to the agrument that “uncertainty” was a barrier to rational economic order and therefore needed to be reduced, I argue that “uncertainty” was manufactured, objectified, and reified in the course of developing industrial bureacracies. Using an alternative historical narrative I demonstrate that “uncertainty” was used to increase the “rationality” (...) — i.e., control — of hierarchies and to enhance the legitimacy of “rational planning.” In other words, strategies to “reduce uncertainty” increased the “certainty” — i.e., control and centrality — of rational planners but increased the “uncertainty” of their subordinates. I point to the fact that the “uncertainty reduction” argument became a central element in the professional idelogy of management and a focal point in management education programs. Furthermore, the canonical organization theory in the social sciences adopted the rhetoric, logic, and epistemlogy produced by the agents under its study and disseminated their ideology. Through their interrelationship in organization theory, “uncertainty” and “rationality” were enacted as two binary opposites that reproduce each other and construct one “coherent” scheme. (shrink)

The dominance of the modern concept of risk and calculability is challenged by and has to be distinguished from “manufactured uncertainties.” Typically today, conflict and controversy flare up around this particular type of new manufactured risk. Neither natural disasters – threats – coming from the outside and thus attributable to God or nature have this effect any longer. Nor do the specific calculable uncertainties – “risks” – which are determinable with actuarial precision interms of a probability calculus backed (...) up by insurance and monetary compensation fall in this category. At the centre of attention today, by contrast, are “manufactured uncertainties.” They are distinguished by the fact that they are dependent on human decisions, created by society itself, immanent to society and thus non-externalizable, collectively imposed and thus individually unavoidable. (shrink)

This paper is motivated by the need to respond to the spread of influential misinformation and manufactured ignorance, which places pressure on the work of experts in various sectors. To meet this need, the paper discusses the conditions required for expert testimony to evolve a reconceptualisation of negative capability as a new form of epistemic humility. In this regard, professional knowledge formation is not considered to be separate from the institutional and social processes and values that uphold its production. (...) Drawing attention to the structural and relational aspects of ignorance, as opposed to the individualistic and internal aspects, we rely on the sociology of knowledge, the social epistemologies and the feminist epistemologies that have played a fundamental role in the development of the investigation of ignorance. First, we analyse the criteria for epistemic humility based on prior theoretical discussions concerning negative knowledge as a form of reflective practice. Then, we seek to determine what kinds of strategies, virtues and skills experts need to have so as to ‘manage ignorance’ in socially complex situations. Finally, we suggest the reformulation of negative expertise as a phronetic skill for navigating through situations of ignorance and uncertainty in an epistemically and socially responsible manner. (shrink)

The kilogram prototype is an object manufactured in late nineteenth century to serve as the standard unit of mass worldwide. Since then, the kilogram definition has been determined by this unique object, making it a peculiar case in metrological studies. However, after realizing that the prototype’s mass was unexpectedly changing, scientists are seeking a new way to define the kilogram in pure mathematical terms.

Recent criticisms of traditional understandings of risk, responsibility and the division of labour between science and politics build on the idea of the co-produced character of the natural and social orders, making a case for less ambitious and more inclusive policy processes, where questions of values and goals may be addressed together with questions of facts and means, causal liabilities and principled responsibilities. Within the neo-liberal political economy, however, the contingency of the world is depicted as a source of unprecedented (...) opportunities for human craftsmanship, rather than of possibly unmanageable surprises. Gene technologies offer a vantage point for reflecting on the consequences of the drift from discovery to invention as a master frame in the appraisal of human intermingling with the world. Biotech patenting regulations carve out a sovereign agency which, by crafting nature, also crafts the distinction between the manufactured and non-manufactured world. Difficulties in ascribing responsibility stem as a consequence. It is likely that politics and economy can be democratized and responsibilities rearranged not by ‘democratizing’ knowledge production, but rather the reverse. (shrink)

Orientation: This study investigated the influence of authentic leadership on employee flourishing while considering the potential mediating effect of trust in the organization and organizational support as underlying mechanisms in an uncertain setting.Research purpose: To examine the relationship between authentic leadership and employee flourishing by evaluating the indirect effect of organizational support and trust in the organization as potential mediators.Motivation for the study: An authentic leadership approach, organizational support, and trust in the organization may influence the flourishing of employees in (...) uncertain times. Increasing the comprehension of the possible interaction effect of organizational support and trust in the organization in the relationship between authentic leadership and employee flourishing may improve individual and organizational efficiency.Research approach/design and method: A quantitative, cross-sectional survey design was applied in this study. The sample comprised 314 employees in a noteworthy South African steel manufacturing entity. The Authentic Leadership Inventory, Workplace Trust Survey, Flourishing-at-Work Scale, and the Job Demands-Resources Scale were administered.Main findings: The findings of this study suggest that authentic leadership was a significant predictor of employee flourishing through organizational support and trust in the organization.Practical/managerial implications: This research illuminates the potential value-adding contribution of an authentic leadership style in promoting a trust-filled relationship between team members and their organization and the support they experience from their employer. Despite the prevailing precarious context, working under the mentioned conditions might result in the increased flourishing of employees.Contribution/value-add: The analyses of the mentioned relationships might assist businesses in optimizing the resources required to improve employee and organizational performance. Additionally, the exploration of organizational support in conjunction with organizational trust raises our understanding of the possible influence these elements can have in enhancing employee flourishing in the workplace. (shrink)

In Science as Social Knowledge in 1990 and The Fate of Knowledge in 2002, Helen Longino develops an epistemological theory known as Critical Contextual Empiricism (CCE). Knowledge production, she argues, is an active, value-laden practice, evidence is context dependent and relies on background assumptions, and science is a social inquiry that, under certain conditions, produces social knowledge with contextual objectivity. While Longino’s work has been generally well-received, there have been a number of criticisms of CCE raised in the philosophical literature (...) in recent years. In this paper I outline the key elements of Longino’s theory and propose modifications to the four norms offered by the account. The version of CCE I defend, which draws on lessons learned by medical researchers in recent years, gives principles of epistemic diversity a central role and also provides greater specification of three of the four norms. Further, it offers additional resources for defending CCE against Alvin Goldman’s suggestion that there is a need for a “healthy dogmatism” in science, as well as a concern about “manufactured uncertainty” arising out of recent work by David Michaels. Finally, the modified version proposed here is also well positioned to respond (negatively) to a suggestion from Kristen Intemann that CCE needs to be adapted to incorporate a central insight from feminist standpoint theory. In light of the variety of social pressures influencing contemporary scientific research, and the role of science in shaping public policy, I argue that a rigorous social epistemology such as CCE is indispensable for understanding and assessing contemporary scientific practice. (shrink)

This article considers some political potentialities of the post-constructivist proposal for substituting truth with traceability. Traceability is a measure of truthfulness in which the rationality of a truth-claim is found in accounting for the work done to maintain links back to an internal referent through a chain of mediations. The substitution of traceability for truth is seen as necessary to move the entire political domain towards a greater responsiveness to the events of the natural-social world. In particular, it seeks to (...) disarm the strategy of ... (shrink)

The quest for effective medicines is very old. In modern times two important tools have been developed to evaluate efficacy of drugs: superiority and non-inferiority types of clinical trials. The former tests the null hypothesis of μ (the difference between a tested drug and comparator) ≤ 0 against μ > 0; the latter tests the null hypothesis of μ ≤ - Δ against, μ > - Δ, where Δ is the clinical difference from the comparator. In a superiority trial, a (...) new drug is tested against a placebo; in a non-inferiority trial, a new drug is tested against active treatment. In this paper, arguments are presented to show that a superiority trial against a placebo is scientifically sound but ethically unacceptable, whereas a non-inferiority trial against active treatment is ethically sound but scientifically not reliable. Switching from a superiority type of trial with placebo to a non-inferiority trial with an active-control — following the latest revision of Declaration of Helsinki — is in practice switching from the violation of the uncertainty principle to uncertainty of results. Given human and financial resources, it appears an academic question as to which is more unethical: to violate patients’ rights or to produce results without scientific value. All presented considerations lead to the conclusion that the use of a superiority trial of design with an active control instead of placebo will satisfy scientific needs, expectation of patients, and the ancient quest for effective medicines. In the era of Good (Clinical, Laboratory, Manufacture) Practice, the attention of those performing clinical trials is focused on the procedure, not always on its essence. However even the excellent performance of a trial which is not worth doing is fruitless. (shrink)

This paper deals with current problems of innovation in manufacturing industries. The shortcomings are analysed as contradictions within the conventional modernity. The main characteristic that makes the transition from modernity to reflexive modernity in an era of not intentional side effects is the omnipresent increase of uncertainties at various societal levels. Furthermore, the emerging need for culturally appropriate regionalized products contributes to the need for a reconsideration of innovation assumptions and goals, which will end up with a reflexive innovation of (...) innovation. Finally, the innovation of innovation is embedded in the concept of culture of manufacturing, which provides a framework for assessing the prospects of trans-disciplinary collaboration between engineers and social scientists. (shrink)

Technology is a practically indispensible means for satisfying one’s basic interests in all central areas of human life including nutrition, habitation, health care, entertainment, transportation, and social interaction. It is impossible for any one person, even a well-trained scientist or engineer, to know enough about how technology works in these different areas to make a calculated choice about whether to rely on the vast majority of the technologies she/he in fact relies upon. Yet, there are substantial risks, uncertainties, and unforeseen (...) practical consequences associated with the use of technological artifacts and systems. The salience of technological failure (both catastrophic and mundane), as well as technology’s sometimes unforeseeable influence on our behavior, makes it relevant to wonder whether we are really justified as individuals in our practical reliance on technology. Of course, even if we are not justified, we might nonetheless continue in our technological reliance, since the alternatives might not be attractive or feasible. In this chapter I argue that a conception of trust in technological artifacts and systems is plausible and helps us understand what is at stake philosophically in our reliance on technology. Such an account also helps us understand the relationship between trust and technological risk and the ethical obligations of those who design, manufacture, and deploy technological artifacts. (shrink)

One of the main fields of research in genome editing is the manufacture of transgenic organisms. If this includes genetically human components, then we must not only ask whether such techniques should be allowed, but also what the moral status of “cross species beings” with a genetically “human” component would be and whether the possibility to manufacture them affects the validity of bioethical arguments from species affiliation. In my chapter I want to show that the two latter questions are less (...) dramatic than it might seem, because most, if not all transgenic organisms are not real “interspecies beings”, but rather belong to one of the original species, or constitute a new species. As for the first question, possible epistemic uncertainties about the status of transgenic organisms call for a precautionary approach. (shrink)

This study treats firm productivity as an accumulation of productive intangibles and posits that stakeholder engagement associated with better corporate social performance helps develop such intangibles. We hypothesize that because shareholders factor improved productive efficiency into stock price, productivity mediates the relationship between corporate social and financial performance. Furthermore, we argue that key stakeholders’ social considerations are more valuable for firms with higher levels of discretionary cash and income stream uncertainty. Therefore, we hypothesize that those two contingencies moderate the (...) mediated process of corporate social performance with financial performance. Our analysis, based on a comprehensive longitudinal dataset of the U.S. manufacturing firms from 1992 to 2009, lends strong support for these hypotheses. In short, this paper uncovers a productivity-based, context-dependent mechanism underlying the relationship between corporate social performance and financial performance. (shrink)

The discovery of CRISPR/cas9 has opened new avenues in gene editing. This system, usually considered as molecular scissors, permits the cutting of the DNA at a targeted site allowing the introduction of new genes or the removal or the modification of existing ones. The genome-editing, involving gene drive or not, is then considered with a strong interest in a variety of fields ranging from agriculture to public health and conservation biology. Given its controversial aspects, it is then no surprise that (...) actors in biodiversity conservation do express conflicting views on this emerging and disruptive technology. The positions are ranging from a request for a moratorium to the will to test and deploy it in strategies aiming at eradicating invasive species of mammals on islands. Reviewing some of its recent developments brings light on the conflicts of interest, the financial support, and lobbying currently occurring in this growing field of biotechnology. While an optimistic view on the use of gene drive for ecosystem conservation was first promoted by several molecular biologists, the risks and uncertainties associated have now led to some reservations. Overall, the eventual use of this novel approach for conservation raises concerns related to the engagement of the public, the communication between scientists, and the public and the risk of a manufactured consent. There are also a series of essential ethical and philosophical questions on the relations we have with Nature that needs to be answered. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Re-examining Empirical Data on Conflicts of Interest Through the Lens of Personal NarrativesEmily E. Anderson and Elena M. KrausIntroductionThe personal stories submitted by physicians and researchers for this symposium add much–needed dimension to conversations on conflicts of interest in medicine and research. Narratives from individuals living with conflicts of interest can serve as a unique lens through which to consider psychological and economic theories and survey data on physician (...) and patient views. In our reading of these personal narratives, we identified four primary themes that will serve as springboards for our commentary. We aim to triangulate clusters of meaning drawn from the narratives with relevant data from published empirical studies and identify gaps in knowledge where more research is needed. These themes are: the unique environments of medicine and research; weighing the potential benefits of conflicts of interest against the risks; conflict of interest management; and the roles and responsibilities of diverse stakeholder groups.The Unique Challenges of the Medical and Research EnvironmentsThe reflections of the narrative authors draw attention to many of the unique environmental aspects of medicine and medical research that make physicians and researchers especially vulnerable to conflicts of interest. Conflicts of interest may be more ubiquitous in medicine than in any other industry (Kassirer, 2006). As the narratives demonstrate, conflicts of interest emerge across a range of health care delivery and research activities. Surveys have shown that 94 percent of physicians have some kind of relationship with industry (Campbell, Gruen, Mountford, et al., 2007). There is also evidence that physician interactions with medical industry begin early and are a regular part of a physician’s professional practice along the career continuum (Wazana, 2000).Medicine as a profession is distinct from banking or law. It is often said that medicine is an art; in treating patients, creative individualized solutions and gut instinct are as (if not more) important than the application of scientific knowledge. Uncertainty surrounds medical decision making. There is limited precision with respect to diagnoses and prognoses, limited data regarding the effectiveness of many treatments, and a range of patient values and preferences. Because of this uncertainty, rules about practice standards, especially with respect to avoidance and management of conflicts of interest, cannot be as explicit as they are in law or business. As demonstrated by the story presented by Sal Cruz–Flores, research and practice often intersect. And, there is no system in greater need of reform—and no system about which there are more divergent opinions as to what shape that reform should take—than the United States health care [End Page 91] system. The narratives of Tony Mikulec, Govind Nagaldinne, and David M. Zientek demonstrate how various aspects of the structure of healthcare service provision and third–party payer arrangements have the potential to harm patients. Conflicts of interest comprise more than relationships with pharmaceutical and medical device manufacturers.The narratives of Laura Jean Bierut and David M. Zientek also discuss examples of conflicts of interest that arise from factors beyond relationships with industry or the direct potential for financial gain. This may be somewhat unique to the medical milieu. Non-financial conflicts such as a desire for the prestige bestowed upon scientists who make key discoveries, a requirement to publish for tenure and promotion, the need to maintain one’s license or other privileges, or simply the pressure of a competitive environment can influence physician and researcher behavior. As noted by Bierut, more research on how to identify and manage non-financial conflicts is needed.The Potential Benefits and Harms of Conflicts of InterestConflicts of interest are usually presented in a negative light, particularly those that involve physician relationships with the pharmaceutical industry. To “have a conflict of interest” is to be in a situation or role where there is potential for personal interests to be prioritized over professional responsibilities. However, in terms of public perception, it seems that conflicts of interest have become almost synonymous with wrongdoing. Perhaps this is due to the barrage of media reports during the last decade on significant harms caused by financial conflicts of interest in business, journalism, and sports as well as in medicine (Steinbrook, 2004). Amidst... (shrink)

Throughout Mary Shelley’s early life, she was exposed to numerous well-known and influential people regarding cultural, political, and socio-economic matters. As she began writing, these influences undoubtedly played a role in her narrative. Her novel, _Frankenstein_, written during the time of the first Industrial Revolution in Britain, was one such novel that exhibited her political and economic influences through science fiction. This article addresses many of those influences, including the introduction of the machine into manufacturing. It further addresses how Frankenstein’s (...) Monster may have been one of the first created forms of artificial intelligence (AI). We further expound upon many economic concepts that have persisted through time and are relevant today given the faciliatory aspects, as well as the uncertainty, of AI. We relate these through the literary piece _Frankenstein_ to explore how a two-century-year-old tale provides a blueprint for understanding the conflict among humans and machines and provides a roadmap for harmonization in the past, present, and future. (shrink)

_The Business of Being Made_ is the first book to critically analyze assisted reproductive technologies from a transdisciplinary perspective integrating psychoanalytic and cultural theories. It is a ground-breaking collection exploring ARTs through diverse methods including interview research, clinical case studies, psychoanalytic based ethnography, and memoir. Gathering clinicians and researchers who specialize in this area, this book engages current research in psychoanalysis, sociology, anthropology, philosophy and debates in feminist, queer and cultural theory about affect, temporality, and bodies. With psychoanalysis as its (...) fulcrum, _The Business of Being Made_ explores the social constructions and personal experiences of ARTs. Katie Gentile frames the cultural context, exploring the ways ARTs have become a complex form of playing with time, attempting to manufacture a hopeful future in the midst of growing global uncertainty. The contributors then present a range of varied experiences related to ARTs, including: Interviews with women and men undergoing ARTs; A psychoanalytic memoir of male infertility; Clinical research and work with transgender, gay and lesbian patients creating new Oedipal constellations, the experiences of LBGTQ people within the medical system and the variety of families that emerge; Research on the experiences of egg donors and a corresponding clinical case study of successful egg donation; The experiences of ongoing failure which is the often unacknowledged for ART procedures; How and when people choose to stop using ARTs; A psychoanalytic ethnography of a neonatal intensive care unit populated in part with the babies created through these technologies and their parents, haggard and in shock after years of failed attempts. Full of original material, _The Business of Being Made_ conveys the ambivalence of these technologies without simplifying their complicated consequences for the bodies of individuals, the family, cultures, and our planet. This book will be relevant to clinicians, medical and psychological personnel working in assisted reproductive technologies and infertility, as well as academics working in the fields of sociology, literature, queer and feminist theories and at the intersections of cultural, critical and psychoanalytic theories. (shrink)

Hip implants have provided life-changing treatment, reducing pain and improving the mobility and independence of patients. Success has encouraged manufacturers to innovate and amend designs, engendering patient hopes in these devices. However, failures of medical implants do occur. The failure rate of the Articular Surface Replacement metal-on-metal hip system, implanted almost 100,000 times world-wide, has re-opened debate about appropriate and timely implant governance. As commercial interests, patient hopes, and devices' governance converge in a socio-technical crisis, we analyse the responses of (...) relevant governance stakeholders in the United Kingdom between 2007 and 2014. We argue that there has been a systemic failure of the governance system entrusted with the safety of patients fitted with medical implants. Commercial considerations of medical implants and the status quo of medical implant governance have been given priority over patient safety despite the availability of significant failure data in an example of uncertainty about what constitutes appropriate precautionary action. (shrink)

The emergence of COVID-19 places the economy at risk of recession or worst, depression. A sharp decline in the country’s economic growth is primarily caused by the weak consumption of locals and non-existence of foreign tourists in the country. On the other hand, disruptions of the supply chain in the manufacturing and retails sectors make the situation much worse. With clear uncertainties in mind, government agencies must lay down economic policies, monetary and fiscal, that would boost the confidence of the (...) consumers and producers. Lastly, a clear and coordinated efforts of the national and local government together with economic agencies of the country must be present at this time of the pandemic. (shrink)

As is clear to any user of software, quality control of software has not reached the same levels of sophistication as it has with traditional manufacturing. In this paper we argue that this is because insufficient thought is being given to the methods of reasoning under uncertainty that are appropriate to this domain. We then describe how we have built a large-scale Bayesian network to overcome the difficulties that have so far been met in software quality control. This exploits (...) a number of recent advances in tool support for constructing large networks. We end the paper by describing how the network was validated and illustrate the range of reasoning styles that can be modelled with this tool. (shrink)

In general, there are two ways to approach cognition. One is to start with the features of the human case and try to generalize to other species. Another is to start with the biological conditions under which natural cognition evolved and currently operates and ask what organisms do such that they might require cognition. A full account of cognition requires both. Cognitive biology, however, requires a biogenic approach. Tight integration with biological knowledge places strong constraints on cognitive explanation. These constraints (...) arise from the fact that cognition evolved in a particular context with very special features. All organisms are complex, self-organizing, dynamical systems that exist far from thermodynamic equilibrium and actively maintain themselves in this statistically improbable state by continuously manufacturing the components of the processes that sustain them. Organisms thus must interact with the world in ways that allow them to actively secure matter and energy. They are also persistence-valuing systems: most organisms have mechanisms for resisting or avoiding perturbations that threaten their integrity. A biogenic approach thus stresses the role of mechanisms that facilitate system persistence, for example, those that integrate information concerning external and internal states of affairs to facilitate adaptive behaviour; differentiate some states of affairs from others; invest different properties of the environment with different degrees of salience; appraise system needs relative to prevailing conditions, the potential for interaction, and whether the current interaction is succeeding ; and reduce the impact of random perturbations on system functioning, of which there are many, potentially lethal sources. These are recognisably cognitive functions. Mounting evidence suggests that even bacteria grapple with problems long familiar to cognitive scientists, including: integrating information from multiple sensory channels to marshal an effective response to fluctuating conditions; making decisions under conditions of uncertainty; communicating with conspecifics and others ; and coordinating collective behaviour to increase the chances of survival. Thus a biogenic approach not only justifies the use of very simple biological models to study cognition, it suggests that this is precisely where we ought to look to ascertain the general logic of the function, as well as the mechanisms that carry it out. (shrink)

A number of recent reports and overviews on the ethical and societal problems of nanotechnology present a public that is polarized about nanotechnology. Very little responsible analysis can be found between those poles for two reasons. First, the debate about the highly controversial notion of molecular manufacturing introduced by Eric Drexler shaped much of the early discussion. Second, the polarization can be seen as a consequence of uncertainty about nanotechnology compounded by cognitive barriers. A reporter to UNESCO acknowledges that (...) “…Assessments of nanotechnology tend to radically diverge…These radically diverging assessments that have thus far dominated the debate on nanotechnology seem to be due to a lack of common ground.” The “lack of common ground” is not unprecedented in the history of technology, and scientists rightfully fear a new “GMO debacle.”. (shrink)

The interruption of supply chain caused by unexpected events results in great economic losses. In this paper, we consider that the supply chain risk management consists of a manufacturer and a retailer faced with demand and supply uncertainties caused by the interruption of supply chain. We consider that the manufacturer transfers the disruption risk by purchasing BI insurance. Three models are established to illustrate the impact of insurance on supply chain decision-making under risk. It is observed that business interruption insurance (...) can increase the retailer’s order quantity and supply chain profit. The higher the interrupt probability is, the more obvious the value of the business interruption insurance is. Furthermore, the retailer helps the manufacturer to share the premium, and the manufacture shares the proceeds of insurance with the retailer, which can stimulate retailer to order more and increase the profit of manufacturer and retailer. (shrink)

AbstractIn marketing channels, distributor whistleblowing can deter unethical behaviors, though little academic research investigates this tactic. Drawing on whistleblowing literature in business ethics and organizational theory, as well as field interviews with channel managers, this article identifies and elucidates the notion of distributor whistleblowing in marketing channels. Specifically, this study investigates how a manufacturer’s control modes (monitoring and incentives) encourage or discourage distributor whistleblowing. This study also considers the impact of distributor whistleblowing on relationship quality and the moderating effects of (...) exchange hazards (i.e., transaction-specific investments and market uncertainty). The empirical results from a sample of 211 Chinese distributors indicate that manufacturers’ monitoring inhibits, whereas incentives boost distributor whistleblowing. Further, a positive link arises between distributor whistleblowing and relationship quality, which is weakened by distributor transaction-specific investments and strengthened by market uncertainty. (shrink)

The Journal of Medical Ethics can sometimes read part Men Like Gods and part A Brave New World. At times, we learn how all controversies can resolved with reference to four principles. At other times, we learn how “every discovery in pure science is potentially subversive”.1 This issue is no exception. Here, we can read about the utopia of gene editing, manufactured organs, and machine learnt algorithmic decision-making. We can also read about the dystopia of inherited disorders from edited (...) germlines, the testing of xenotransplants on braindead patients, and misdiagnosis by artificial intelligence. What we see in the three papers that I will foreground here is the application of medical ethics to avoid the dystopia while preserving the promises of medical science. But as I seek to explain here, our ability to address the controversies that we anticipate in medical science depend on our ability to refine our understanding of what medical ethics requires of us now. From the diagnosis of eye diseases from fungus images to predicting the risk of imminent risk of suicide attempts, machine learnt medical decision making has, in some high profile instances, outperformed clinicians in medical diagnosis and treatment recommendations. While clinician and machine learnt diagnoses will both involve degrees of uncertainty and fallibility, Thomas Grote2 asks us to consider is how much weight a clinician ought to give an algorithmic diagnosis which she disagreements with. Since a clinician is held to account for …. (shrink)

In an age where issues like climate change and the unintended consequences of technological innovation are high on the ethical and political agenda, questions about the nature and extent of our responsibilities to future generations have never been more important, yet simultaneously so difficult to answer. This book takes a unique approach to the problem by drawing on diverse traditions of thinking about care (including developmental psychology, phenomenology and feminist ethics) to explore the nature and meaning of our relationship with (...) the future. Demonstrating that many influential perspectives on intergenerational ethics, including positions advanced by John Rawls, Brian Barry, and Ulrich Beck are undermined by problems relating to uncertainty, it shows that an approach based on care ethics can confront the uncertain future successfully and give a viable account of the nature and scope of future-oriented responsibilities. (shrink)

In this paper, I enter the debate between those who hold that our normative uncertainty matters for what we ought to do, and those who hold that only our descriptive uncertainty matters. I argue that existing views in both camps have unacceptable implications in cases where our descriptive beliefs depend on our normative beliefs. I go on to propose a fix which is available only to those who hold that normative uncertainty matters, ultimately leaving the challenge as (...) a threat to recent skepticism about such views. (shrink)

This paper explores the role of moral uncertainty in explaining the morally disruptive character of new technologies. We argue that existing accounts of technomoral change do not fully explain its disruptiveness. This explanatory gap can be bridged by examining the epistemic dimensions of technomoral change, focusing on moral uncertainty and inquiry. To develop this account, we examine three historical cases: the introduction of the early pregnancy test, the contraception pill, and brain death. The resulting account highlights what we (...) call “differential disruption” and provides a resource for fields such as technology assessment, ethics of technology, and responsible innovation. (shrink)

Abstract: There are epistemic manipulators in the world. These people are actively attempting to sacrifice epistemic goods for personal gain. In doing so, manipulators have led many competent epistemic agents into believing contrarian theories that go against well-established knowledge. In this paper, I explore one mechanism by which manipulators get epistemic agents to believe contrarian theories. I do so by looking at a prominent empirical model of trustworthiness. This model identifies three major factors that epistemic agents look for when trying (...) to determine who is trustworthy. These are (i) ability, (ii) benevolence, and (iii) moral integrity. I then show how manipulators can manufacture the illusion that they possess these factors. This leads epistemic agents to view manipulators as trustworthy sources of information. Additionally, I argue that fact-checking will be an ineffective – or even harmful – practice when correcting the beliefs of epistemic agents who have been tricked by this illusion of epistemic trustworthiness. I suggest that in such cases we should use an alternative correction, which I call trust undercutting. (shrink)

In this chapter I explore the phenomenon of dehumanization in relation to public policy. Using two examples of spectacle lynchings of African Americans, I articulate a conception of dehumanization as the attitude of conceiving of others as subhuman creatures and explain the psychological basis for this phenomenon. I suggest that dehumanization is pertinent to policies concerning hate speech. I address objections to my conception of dehumanization: that dehumanizers implicitly or explicitly acknowledge the humanity of their victims and that dehumanizers regard (...) their victims not merely as animals but also as demons and monsters. I explain how these objections can be met. (shrink)

How is it that thoroughly physical material beings such as ourselves can think, dream, feel, create and understand ideas, theories and concepts? How does mere matter give rise to all these non-material mental states, including consciousness itself? An answer to this central question of our existence is emerging at the busy intersection of neuroscience, psychology, artificial intelligence, and robotics.In this groundbreaking work, philosopher and cognitive scientist Andy Clark explores exciting new theories from these fields that reveal minds like ours to (...) be prediction machines - devices that have evolved to anticipate the incoming streams of sensory stimulation before they arrive. These predictions then initiate actions that structure our worlds and alter the very things we need to engage and predict. Clark takes us on a journey in discovering the circular causal flows and the self-structuring of the environment that define "the predictive brain." What emerges is a bold, new, cutting-edge vision that reveals the brain as our driving force in the daily surf through the waves of sensory stimulation. (shrink)

What skills are required for working with computer-controlled machines in the manufacturing area? Taking the developments in the machine building sector in Germany as an example, it becomes apparent that a human-centred approach (skill-based manufacturing) offers the companies many advantages over Tayloristic forms of work organisation and automation. Closer observations reveal that skills and qualifications based on empirical knowledge and individual capabilities, such as a feeling for machines and materials, continue to play an important part in the work with computer-controlled (...) machines. So far, however, skills of this kind have received neither practical nor systematic consideration and are regarded as tacit skills in most cases. Therefore it is particularly the use of computer technology which is likely — in most cases unintentionally — to restrict and undermine the essential preconditions necessary for the development and application of such skills. (shrink)

The anthropological approach is the central focus of this study. Laboratories are looked upon with the innocent eye of the traveller in exotic lands, and the societies found in these places are observed with the objective yet compassionate eye of the visitor from a quite other cultural milieu. There are many surprises that await us if we enter a laboratory in this frame of mind... This study is a realistic enterprise, an attempt to truly represent the social order of life (...) in laboratories and institutes of research, just as they are. By bringing the philosophical issues to the surface as matters not of prejudgement but as matters of concern, Karin Knorr-Cetina has developed the first really positive challenge to the philosophy of science since the days of paradigms and internal definitions of meanings. (shrink)

The new paradigm in the psychology of reasoning adopts a Bayesian, or prob- abilistic, model for studying human reasoning. Contrary to the traditional binary approach based on truth functional logic, with its binary values of truth and falsity, a third value that represents uncertainty can be introduced in the new paradigm. A variety of three-valued truth table systems are available in the formal literature, including one proposed by de Finetti. We examine the descriptive adequacy of these systems for natural (...) language indicative condi- tionals and bets on conditionals. Within our framework the so-called “defective” truth table, in which participants choose a third value when the antecedent of the indicative conditional is false, becomes a coherent response. We show that only de Finetti’s system has a good descriptive fit when uncer- tainty is the third value. (shrink)

In this essay, we explore an issue of moral uncertainty: what we are permitted to do when we are unsure about which moral principles are correct. We develop a novel approach to this issue that incorporates important insights from previous work on moral uncertainty, while avoiding some of the difficulties that beset existing alternative approaches. Our approach is based on evaluating and choosing between option sets rather than particular conduct options. We show how our approach is particularly well-suited (...) to address this issue of moral uncertainty with respect to agents that have credence in moral theories that are not fully consequentialist. (shrink)

The development of manufacturing technologies for new materials involves the generation of a large and continually evolving volume of information. The analysis, integration and management of such large volumes of data, typically stored in multiple independently developed databases, creates significant challenges for practitioners. There is a critical need especially for open-sharing of data pertaining to engineering design which together with effective decision support tools can enable innovation. We believe that ontology applied to engineering (OE) represents a viable strategy for the (...) alignment, reconciliation and integration of diverse and disparate data. The scope of OE includes: consistent capture of knowledge pertaining to the types of entities involved; facilitation of cooperation among diverse group of experts; more effective ongoing curation, and update of manufacturing data; collaborative design and knowledge reuse. As an illustrative case study we propose an ontology focused on the representation of composite materials focusing in particular on the class of Functionally Graded Materials (FGM) in particular. The scope of the ontology is to provide information about the components of such materials, the manufacturing processes involved in creation, and diversity of application ranging from additive manufacturing to restorative dentistry. The ontology is developed using Basic Formal Ontology (BFO) and the Ontology for Biomedical Investigations (OBI). (shrink)

Evolving manufacturing management strategies pose changing business ethical challenges to the companies and society. The evolution is not one that continuously improves the business ethical performance, some aspects improve it and some other are detrimental. This paper explores the business ethical implications of the evolution of manufacturing management starting at the pre-industrial workshops until the introduction of agile manufacturing based on business ethical criteria drawn from business ethics (applied moral theory) and environmental law.

Model evaluation for long term climate predictions must be done on quantities other than the actual prediction, and a comprehensive uncertainty quantification is impossible. An ad hoc alternative is provided by coordinated model intercomparisons which typically use a “one model one vote” approach. The problem with such an approach is that it treats all models as independent and equally plausible. Reweighting all models of the ensemble for performance and dependence seems like an obvious way to improve on model democracy, (...) yet there are open questions on what constitutes a “good” model, how to define dependency, how to interpret robustness, and how to incorporate background knowledge. Under¬standing those issues has the potential to increase confidence in model predictions in modeling efforts outside of climate science where similar challenges exist. (shrink)

How should we make decisions when we're uncertain about what we ought, morally, to do? Decision-making in the face of fundamental moral uncertainty is underexplored terrain: MacAskill, Bykvist, and Ord argue that there are distinctive norms by which it is governed, and which depend on the nature of one's moral beliefs.

Defenders of deontological constraints in normative ethics face a challenge: how should an agent decide what to do when she is uncertain whether some course of action would violate a constraint? The most common response to this challenge has been to defend a threshold principle on which it is subjectively permissible to act iff the agent's credence that her action would be constraint-violating is below some threshold t. But the threshold approach seems arbitrary and unmotivated: what would possibly determine where (...) the threshold should be set, and why should there be any precise threshold at all? Threshold views also seem to violate ought agglomeration, since a pair of actions each of which is below the threshold for acceptable moral risk can, in combination, exceed that threshold. In this paper, I argue that stochastic dominance reasoning can vindicate and lend rigor to the threshold approach: given characteristically deontological assumptions about the moral value of acts, it turns out that morally safe options will stochastically dominate morally risky alternatives when and only when the likelihood that the risky option violates a moral constraint is greater than some precisely definable threshold (in the simplest case, .5). I also show how, in combination with the observation that deontological moral evaluation is relativized to particular choice situations, this approach can overcome the agglomeration problem. This allows the deontologist to give a precise and well-motivated response to the problem of uncertainty. (shrink)

As well as disagreeing about how much one should donate to charity, moral theories also disagree about where one should donate. In light of this disagreement, how should the morally uncertain philanthropist allocate her donations? In many cases, one intuitively attractive option is for the philanthropist to split her donations across all of the charities that are recommended by moral views in which she has positive credence, with each charity’s share being proportional to her credence in the moral theories that (...) recommend that particular charity. Despite the fact that something like this approach is already being used by real-world philanthropists to distribute billions of dollars of donations, it is not supported by any of the approaches to moral uncertainty that have been proposed thus-far in the philosophical literature. In this paper, we will develop a bargaining-based approach to moral uncertainty that honors the proportionality intuition in favor of splitting one’s donations. We also show how this bargaining-based approach has several further advantages over the best alternative proposals. (shrink)

We are sometimes unsure of the moral status of our relationships with other entities. Recent case studies in this uncertainty include our relationships with artificial agents (robots, assistant AI, etc.), animals, and patients with “locked-in” syndrome. Do these entities have basic moral standing? Could they count as true friends or lovers? What should we do when we do not know the answer to these questions? An influential line of reasoning suggests that, in such cases of moral uncertainty, we (...) need meta-moral decision rules that allow us to either minimize the risks of moral wrongdoing or improve the choice-worthiness of our actions. One particular argument adopted in this literature is the “risk asymmetry argument,” which claims that the risks associated with accepting or rejecting some moral facts may be sufficiently asymmetrical as to warrant favoring a particular practical resolution of this uncertainty. Focusing on the case study of artificial beings, this article argues that this is best understood as an ethical-epistemic challenge. The article argues that taking potential risk asymmetries seriously can help resolve disputes about the status of human–AI relationships, at least in practical terms (philosophical debates will, no doubt, continue); however, the resolution depends on a proper, empirically grounded assessment of the risks involved. Being skeptical about basic moral status, but more open to the possibility of meaningful relationships with such entities, may be the most sensible approach to take. (shrink)

This chapter contains sections titled: Practical Ethics Practical Ethics and Hold Manufacturing Reason 1: Rock Modification is Acceptable Only for Safety Reasons Reason 2: Hold Manufacturing Violates Important Environmental Commitments Reason 3: Hold Manufacturing Harms Future Generations of Good Climbers Reason 4: This is a Slippery Slope; Any Acceptance of Manufacturing Will Lead to Abuses Conclusion.

In this paper we introduce the nascent literature on Moral Uncertainty Theory and explore its application to the criminal law. Moral Uncertainty Theory seeks to address the question of what we ought to do when we are uncertain about what to do because we are torn between rival moral theories. For instance, we may have some credence in one theory that tells us to do A but also in another that tells us to do B. We examine how (...) we might decide whether or not to criminalize some conduct when we are unsure as to whether or not the conduct is morally permitted, and whether or not it is permissible to criminalize the conduct. We also look at how we might make sentencing decisions under moral uncertainty. We argue that Moral Uncertainty Theory can be an illuminating way to address these questions, but find that doing so is a lot more complicated than applying Moral Uncertainty Theory to individual conduct. (shrink)

Model evaluation for long-term climate predictions must be done on quantities other than the actual prediction, and a comprehensive uncertainty quantificationUncertainty quantification is impossible. An ad hoc alternative is provided by coordinated model intercomparisonsModel intercomparisons which typically use a “one model one vote” approach. The problem with such an approach is that it treats all models as independent and equally plausible. Reweighting all models of the ensemble for performance and dependence seems like an obvious way to improve on model (...) democracy, yet there are open questions on what constitutes a “good” model, how to define dependency, how to interpret robustnessRobustness, and how to incorporate background knowledgeBackground knowledge. UnderstandingUnderstanding those issues have the potential to increase confidence in model predictions in modeling efforts outside of climate scienceClimate science where similar challenges exist. (shrink)

Jennifer Rose Carr’s (2020) article “Normative Uncertainty Without Theories” proposes a method to maximize expected value under normative uncertainty without Intertheoretic Value Comparison (hereafter IVC). Carr argues that this method avoids IVC because it avoids theories: the agent’s credence is distributed among normative hypotheses of a particular type, which don’t constitute theories. However, I argue that Carr’s method doesn’t avoid or help to solve what I consider as the justificatory problem of IVC, which isn’t specific to comparing theories (...) as such. This threatens the implementability of Carr’s method. Fortunately, I also show how Carr’s method can nevertheless be implemented. I identify a type of epistemic states where the justificatory problem of IVC is not a necessary obstacle to maximizing expected value. In such states, the uncertainty stems from indecisive normative intuitions, and the agent justifiably constructs each normative hypothesis on the basis of a consistent subset of her intuitions by reference to the same unit of value. This part of my argument complements not only Carr’s (2020) argument, but also some moderate defenses of IVC. The combination of Carr’s paper and mine helps to illuminate the conditions for maximizing expected value under normative uncertainty without unjustified value comparison. (shrink)