Results for 'Andrea Loettgers'

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  1. Mathematization in Synthetic Biology: Analogies, Templates, and Fictions.Andrea Loettgers & Tarja Knuuttila - 2017 - In Martin Carrier & Johannes Lenhard (eds.), Mathematics as a Tool: Tracing New Roles of Mathematics in the Sciences. Springer Verlag.
    In his famous article “The Unreasonable Effectiveness of Mathematics in the Natural Sciences” Eugen Wigner argues for a unique tie between mathematics and physics, invoking even religious language: “The miracle of the appropriateness of the language of mathematics for the formulation of the laws of physics is a wonderful gift which we neither understand nor deserve”. The possible existence of such a unique match between mathematics and physics has been extensively discussed by philosophers and historians of mathematics. Whatever the merits (...)
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  2.  46
    Model Organisms and Mathematical and Synthetic Models to Explore Gene Regulation Mechanisms.Andrea Loettgers - 2007 - Biological Theory 2 (2):134-142.
    Gene regulatory networks are intensively studied in biology. One of the main aims of these studies is to gain an understanding of how the structure of genetic networks relates to specific functions such as chemotaxis and the circadian clock. Scientists have examined this question by using model organisms such as Drosophila and mathematical models. In the last years, synthetic models—engineered genetic networks—have become more and more important in the exploration of gene regulation. What is the potential of this new approach (...)
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  3.  50
    Synthetic Biology and the Emergence of a Dual Meaning of Noise.Andrea Loettgers - 2009 - Biological Theory 4 (4):340-356.
    The question is discussed how noise gained a functional meaning in the context of biology. According to the common view, noise is considered a disturbance or perturbation. I analyze how this understanding changed and what kind of developments during the last 10 years contributed to the emergence of a new understanding of noise. Results gained during a field study in a synthetic biology laboratory show that the emergence of this new research discipline—its highly interdisciplinary character, its new technologies and novel (...)
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  4.  18
    Getting Abstract Mathematical Models in Touch with Nature.Andrea Loettgers - 2007 - Science in Context 20 (1):97.
  5. Magnetized Memories: Analogies and Templates in Model Transfer.Tarja Knuuttila & Andrea Loettgers - 2020 - In S. Holm & M. Serban (eds.), Biology: Living Machines? Routledge. pp. 123-140.
    One striking feature of the contemporary modeling practice is its interdisciplinarity: the same function forms and equations, and mathematical and computational methods are being transferred across disciplinary boundaries. Within philosophy of science this interdisciplinary dimension of modeling has been addressed by both analogy and template-based approaches that have proceeded separately from each other. We argue that a more fully-blown account of model transfer needs both perspectives. We examine analogical reasoning and template application through a detailed case study on the transfer (...)
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  6.  22
    Correction: What are definitions of life good for? Transdisciplinary and other definitions in astrobiology.Andrea Loettgers & Tarja Knuuttila - 2023 - Biology and Philosophy 38 (2):1-2.
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  7.  56
    How Can History of Science Matter to Scientists?Jane Maienschein, Manfred Laubichler & Andrea Loettgers - 2008 - Isis 99 (2):341-349.
    History of science has developed into a methodologically diverse discipline, adding greatly to our understanding of the interplay between science, society, and culture. Along the way, one original impetus for the then newly emerging discipline—what George Sarton called the perspective “from the point of view of the scientist”—dropped out of fashion. This essay shows, by means of several examples, that reclaiming this interaction between science and history of science yields interesting perspectives and new insights for both science and history of (...)
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  8. Modelling as Indirect Representation? The Lotka–Volterra Model Revisited.Tarja Knuuttila & Andrea Loettgers - 2017 - British Journal for the Philosophy of Science 68 (4):1007-1036.
    ABSTRACT Is there something specific about modelling that distinguishes it from many other theoretical endeavours? We consider Michael Weisberg’s thesis that modelling is a form of indirect representation through a close examination of the historical roots of the Lotka–Volterra model. While Weisberg discusses only Volterra’s work, we also study Lotka’s very different design of the Lotka–Volterra model. We will argue that while there are elements of indirect representation in both Volterra’s and Lotka’s modelling approaches, they are largely due to two (...)
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  9. Model templates within and between disciplines: from magnets to gases – and socio-economic systems.Tarja Knuuttila & Andrea Loettgers - 2016 - European Journal for Philosophy of Science 6 (3):377-400.
    One striking feature of the contemporary modelling practice is its interdisciplinary nature. The same equation forms, and mathematical and computational methods, are used across different disciplines, as well as within the same discipline. Are there, then, differences between intra- and interdisciplinary transfer, and can the comparison between the two provide more insight on the challenges of interdisciplinary theoretical work? We will study the development and various uses of the Ising model within physics, contrasting them to its applications to socio-economic systems. (...)
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  10. Varieties of noise: Analogical reasoning in synthetic biology.Tarja Knuuttila & Andrea Loettgers - 2014 - Studies in History and Philosophy of Science Part A 48:76-88.
    The picture of synthetic biology as a kind of engineering science has largely created the public understanding of this novel field, covering both its promises and risks. In this paper, we will argue that the actual situation is more nuanced and complex. Synthetic biology is a highly interdisciplinary field of research located at the interface of physics, chemistry, biology, and computational science. All of these fields provide concepts, metaphors, mathematical tools, and models, which are typically utilized by synthetic biologists by (...)
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  11. (Un)Easily Possible Synthetic Biology.Tarja Knuuttila & Andrea Loettgers - 2022 - Philosophy of Science (5):1-14.
    Synthetic biology has a strong modal dimension that is part and parcel of its engineering agenda. In turning hypothetical biological designs into actual synthetic constructs, synthetic biologists reach towards potential biology instead of concentrating on naturally evolved organisms. We analyze synthetic biology’s goal of making biology easier to engineer through the combinatorial theory of possibility, which reduces possibility to combinations of individuals and their attributes in the actual world. While the last decades of synthetic biology explorations have shown biology to (...)
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  12.  56
    Basic science through engineering? Synthetic modeling and the idea of biology-inspired engineering.Tarja Knuuttila & Andrea Loettgers - 2013 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (2):158-169.
    Synthetic biology is often understood in terms of the pursuit for well-characterized biological parts to create synthetic wholes. Accordingly, it has typically been conceived of as an engineering dominated and application oriented field. We argue that the relationship of synthetic biology to engineering is far more nuanced than that and involves a sophisticated epistemic dimension, as shown by the recent practice of synthetic modeling. Synthetic models are engineered genetic networks that are implanted in a natural cell environment. Their construction is (...)
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  13. What are definitions of life good for? Transdisciplinary and other definitions in astrobiology.Tarja Knuuttila & Andrea Loettgers - 2017 - Biology and Philosophy 32 (6):1185-1203.
    The attempt to define life has gained new momentum in the wake of novel fields such as synthetic biology, astrobiology, and artificial life. In a series of articles, Cleland, Chyba, and Machery claim that definitions of life seek to provide necessary and sufficient conditions for applying the concept of life—something that such definitions cannot, and should not do. We argue that this criticism is largely unwarranted. Cleland, Chyba, and Machery approach definitions of life as classifying devices, thereby neglecting their other (...)
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  14. Synthetic Modeling and Mechanistic Account: Material Recombination and Beyond.Tarja Knuuttila & Andrea Loettgers - 2013 - Philosophy of Science 80 (5):874-885.
    Recently, Bechtel and Abrahamsen have argued that mathematical models study the dynamics of mechanisms by recomposing the components and their operations into an appropriately organized system. We will study this claim through the practice of combinational modeling in circadian clock research. In combinational modeling, experiments on model organisms and mathematical/computational models are combined with a new type of model—a synthetic model. We argue that the strategy of recomposition is more complicated than what Bechtel and Abrahamsen indicate. Moreover, synthetic modeling as (...)
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  15.  32
    Basic science through engineering?: Synthetic modeling and the idea of biology-inspired engineering.Tarja Knuuttila & Andrea Loettgers - 2013 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (2):158-169.
    Synthetic biology is often understood in terms of the pursuit for well-characterized biological parts to create synthetic wholes. Accordingly, it has typically been conceived of as an engineering dominated and application oriented field. We argue that the relationship of synthetic biology to engineering is far more nuanced than that and involves a sophisticated epistemic dimension, as shown by the recent practice of synthetic modeling. Synthetic models are engineered genetic networks that are implanted in a natural cell environment. Their construction is (...)
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  16. Magnets, spins, and neurons: The dissemination of model templates across disciplines.Tarja Knuuttila & Andrea Loettgers - 2014 - The Monist 97 (3):280-300.
    One of the most conspicuous features of contemporary modeling practices is the dissemination of mathematical and computational methods across disciplinary boundaries. We study this process through two applications of the Ising model: the Sherrington-Kirkpatrick model of spin glasses and the Hopfield model of associative memory. The Hopfield model successfully transferred some basic ideas and mathematical methods originally developed within the study of magnetic systems to the field of neuroscience. As an analytical resource we use Paul Humphreys's discussion of computational and (...)
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  17. Contrasting Cases: The Lotka-Volterra Model Times Three.Tarja Knuuttila & Andrea Loettgers - 2016 - Boston Studies in the Philosophy of Science 319:151-178.
    How do philosophers of science make use of historical case studies? Are their accounts of historical cases purpose-built and lacking in evidential strength as a result of putting forth and discussing philosophical positions? We will study these questions through the examination of three different philosophical case studies. All of them focus on modeling and on Vito Volterra, contrasting his work to that of other theoreticians. We argue that the worries concerning the evidential role of historical case studies in philosophy are (...)
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  18. The productive tension : mechanisms vs. templates in modeling the phenomena.Tarja Knuuttila & Andrea Loettgers - 2011 - In Paul Humphreys & Cyrille Imbert (eds.), Models, Simulations, and Representations. Routledge.
  19. Causal isolation robustness analysis: the combinatorial strategy of circadian clock research.Tarja Knuuttila & Andrea Loettgers - 2011 - Biology and Philosophy 26 (5):773-791.
    This paper distinguishes between causal isolation robustness analysis and independent determination robustness analysis and suggests that the triangulation of the results of different epistemic means or activities serves different functions in them. Circadian clock research is presented as a case of causal isolation robustness analysis: in this field researchers made use of the notion of robustness to isolate the assumed mechanism behind the circadian rhythm. However, in contrast to the earlier philosophical case studies on causal isolation robustness analysis (Weisberg and (...)
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  20. Biological Control Variously Materialized: Modeling, Experimentation and Exploration in Multiple Media.Tarja Knuuttila & Andrea Loettgers - 2021 - Perspectives on Science 29 (4):468-492.
    This paper examines two parallel discussions of scientific modeling which have invoked experimentation in addressing the role of models in scientific inquiry. One side discusses the experimental character of models, whereas the other focuses on their exploratory uses. Although both relate modeling to experimentation, they do so differently. The former has considered the similarities and differences between models and experiments, addressing, in particular, the epistemic value of materiality. By contrast, the focus on exploratory modeling has highlighted the various kinds of (...)
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  21.  50
    Modeling and experimenting: The combinatorial strategy in synthetic biology.Tarja Knuuttila & Andrea Loettgers - unknown
    In which respects do modeling and experimenting resemble or differ from each other? We explore this question through studying in detail the combinatorial strategy in synthetic biology whereby scientists triangulate experimentation on model organisms, mathematical modeling, and synthetic modeling. We argue that this combinatorial strategy is due to the characteristic constraints of the three epistemic activities. Moreover, our case study shows that in some cases materiality clearly matters, in fact it provides the very rationale of synthetic modeling. We will show (...)
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  22.  39
    Synthetic Biology as an Engineering Science? Analogical Reasoning, Synthetic Modeling, and Integration.Tarja Knuuttila & Andrea Loettgers - 2013 - In Hanne Andersen, Dennis Dieks, Wenceslao González, Thomas Uebel & Gregory Wheeler (eds.), New Challenges to Philosophy of Science. Springer Verlag. pp. 163--177.
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  23.  21
    Model templates: transdisciplinary application and entanglement.Tarja Knuuttila & Andrea Loettgers - 2023 - Synthese 201 (6):1-23.
    The omnipresence of the same basic equations, function forms, algorithms, and quantitative methods is one of the most spectacular characteristics of contemporary modeling practice. Recently, the emergence of the discussion of templates and template transfer has addressed this striking cross-disciplinary reach of certain mathematical forms and computational algorithms. In this paper, we develop a notion of a model template, consisting of its mathematical structure, ontology, prototypical properties and behaviors, focal conceptualizations, and the paradigmatic questions it addresses. We apply this notion (...)
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  24.  18
    Correction to: Model templates within and between disciplines: from magnets to gases – and socio-economic systems.Tarja Knuuttila & Andrea Loettgers - 2023 - European Journal for Philosophy of Science 13 (1):1-2.
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  25.  8
    Modeling/Experimentation: The Synthetic Strategy in the Study of Genetic Circuits.Tarja Knuuttila & Andrea Loettgers - 2018 - In Isabelle Peschard & Bas C. Van Fraassen (eds.), The Experimental Side of Modeling. University of Minnesota Press. pp. 118-147.
  26.  30
    Synthetic Modeling and the Functional Role of Noise.Tarja Knuuttila & Andrea Loettgers - unknown
    In synthetic biology the use of engineering metaphors to describe biological organisms and their behavior has become a common practice. The concept of noise provides one of the most compelling examples of such transfer. But this notion is also confusing: While in engineering noise is a destructive force perturbing artificial systems, in synthetic biology it has acquired an additional functional meaning. It has been found out that noise is an important factor in driving biological processes such as gene regulation, development, (...)
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  27.  7
    Philosophy of science: an introduction for future knowledge workers.Andreas Beck Holm - 2013 - Frederiksberg C: Samfundslitteratur.
    A student's future as a knowledge worker (one who "thinks for a living" with the task of problem solving) is the starting point of this book. With this in mind, the book combines a review of philosophical positions and problems with practical examples and perspectives gained from everyday challenges faced by knowledge workers in their businesses and organizations. Through the use of summative chapters, highlighted key concepts, questions for reflection, and illustrative examples on how to work with the theories presented, (...)
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  28.  48
    Scienza e società della conoscenza.Andrea Cerroni - 2006 - Torino: UTET università.
    Anche se siamo comunemente abituati a pensare alla scienza come a un qualcosa di assolutamente atemporale e indipendente da tutto, in realtà essa è profondamente influenzata dalla cultura e dalla società del tempo in cui vive. Infatti né la scienza è isolabile dalla società, né la società è isolabile dalla scienza, tanto meno come si sta configurando oggi. Per approfondire questi aspetti, esistono però due visioni antagoniste che bisogna superare: secondo la visione scolastica, retaggio del positivismo ottocentesco ancora molto diffuso (...)
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  29.  9
    L'incubo degli ultimi uomini: etica e politica in Max Weber.Dimitri D'Andrea - 2005 - Roma: Carocci.
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  30. Am I Socially Related to Myself?Andreas Bengtson - forthcoming - Erkenntnis:1-18.
    According to relational egalitarianism, justice requires equal relations. The theory applies to those who stand in the relevant social relations. In this paper, I distinguish four different accounts of what it means to be socially related and argue that in all of them, self-relations—how a person relates to themselves—fall within the scope of relational egalitarianism. I also point to how this constrains what a person is allowed to do to themselves.
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  31. The Oxford handbook of Emile Durkheim.Hans Joas & Andreas Pettenkofer (eds.) - 2024 - New York, NY: Oxford University Press.
    Émile Durkheim remains one of the most controversial, and deeply misunderstood, classics of social theory. His work differs from the dominant version of sociology that has essentially accepted the modernist self-description of contemporary societies; and it contradicts the individualism that has come to dominate the social sciences. For everybody who is interested in constructing theoretical alternatives to this individualism, Durkheim's sociology can be a useful inspiration - not only because of the solutions it suggests, but already because of the questions (...)
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  32. The Vienna Circle’s reception of Nietzsche.Andreas Vrahimis - 2020 - Journal for the History of Analytical Philosophy 8 (9):1-29.
    Friedrich Nietzsche was among the figures from the history of nineteenth century philosophy that, perhaps surprisingly, some of the Vienna Circle’s members had presented as one of their predecessors. While, primarily for political reasons, most Anglophone figures in the history of analytic philosophy had taken a dim view of Nietzsche, the Vienna Circle’s leader Moritz Schlick admired and praised Nietzsche, rejecting what he saw as a misinterpretation of Nietzsche as a militarist or proto-fascist. Schlick, Frank, Neurath, and Carnap were in (...)
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  33. Yet another victim of Kripkenstein’s monster: dispositions, meaning, and privilege.Andrea Guardo - 2022 - Ergo 8 (55):857-882.
    In metasemantics, semantic dispositionalism is the view that what makes it the case that, given the value of the relevant parameters, a certain linguistic expression refers to what it does are the speakers’ dispositions. In the literature, there is something like a consensus that the fate of dispositionalism hinges on the status of three arguments, first put forward by Saul Kripke ‒ or at least usually ascribed to him. This paper discusses a different, and strangely neglected, anti-dispositionalist argument, which develops (...)
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  34.  34
    Global Rules and Private Actors: Toward a New Role of the Transnational Corporation in Global Governance.Andreas Georg Scherer, Guido Palazzo & Dorothée Baumann - 2006 - Business Ethics Quarterly 16 (4):505-532.
    Abstract:We discuss the role that transnational corporations (TNCs) should play in developing global governance, creating a framework of rules and regulations for the global economy. The central issue is whether TNCs should provide global rules and guarantee individual citizenship rights, or instead focus on maximizing profits. First, we describe the problems arising from the globalization process that affect the relationship between public rules and private firms. Next we consider the position of economic and management theories in relation to the social (...)
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  35. What Relational Egalitarians Should (Not) Believe.Andreas Bengtson & Lauritz Aastrup Munch - 2024 - Journal of Ethics and Social Philosophy 27 (2).
    Relational egalitarianism is a theory of justice according to which justice requires that people relate as equals. According to some relational egalitarians, X and Y relate as equals if, and only if, they (1) regard each other as equals; and (2) treat each other as equals. In this paper, we argue that relational egalitarians must give up 1.
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  36.  25
    Epistemology and Political Philosophy in Gilbert Simondon.Andrea Bardin - unknown
    Simondon adopts some concepts of social psychology as ‘in group’ and ‘out group’, namely from Kurt Lewin and Gordon Allport, that allow him to describe the fundamental processes shaping the domain of collective individuation, and to challenge Bergson’s distinction between a ‘closed’ community and an ‘open’ society. Reconstructing Simondon’s sources is necessary to understand how he tries to provide an analysis of the social system without presupposing a given anthropology, but rather exploring different perspectives on the human/nature threshold through the (...)
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  37. Climate Change and Decision Theory.Andrea S. Asker & H. Orri Stefánsson - 2023 - In Pellegrino Gianfranco & Marcello Di Paola (eds.), Handbook of Philosophy of Climate Change. Springer Nature. pp. 267-286.
    Many people are worried about the harmful effects of climate change but nevertheless enjoy some activities that contribute to the emission of greenhouse gas (driving, flying, eating meat, etc.), the main cause of climate change. How should such people make choices between engaging in and refraining from enjoyable greenhouse-gas-emitting activities? In this chapter, we look at the answer provided by decision theory. Some scholars think that the right answer is given by interactive decision theory, or game theory; and moreover think (...)
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  38.  37
    Present pasts: urban palimpsests and the politics of memory.Andreas Huyssen - 2003 - Stanford, Calif.: Stanford University Press.
    Memory of historical trauma has a unique power to generate works of art. This book analyzes the relation of public memory to history, forgetting, and selective memory in Berlin, Buenos Aires, and New York—three late-twentieth-century cities that have confronted major social or political traumas. Berlin experienced the fall of the Berlin Wall and the city’s reemergence as the German capital; Buenos Aires lived through the dictatorships of the 1970s and 1980s and their legacy of state terror and disappearances; and New (...)
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  39. Networks in Cognitive Science.Andrea Baronchelli, Ramon Ferrer-I.-Cancho, Romualdo Pastor-Satorras, Nick Chater & Morten H. Christiansen - 2013 - Trends in Cognitive Sciences 17 (7):348-360.
  40.  97
    How to Define Emotions Scientifically.Andrea Scarantino - 2012 - Emotion Review 4 (4):358-368.
    The central contention of this article is that the classificatory scheme of contemporary affective science, with its traditional categories of emotion, anger, fear, and so on, is no longer suitable to the needs of affective science. Unlike psychological constructionists, who have urged the transition from a discrete to a dimensional approach in the study of affective phenomena, I argue that we can stick to a discrete approach as long as we accept that traditional emotion categories will have to be transformed (...)
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  41.  31
    Defending the Structural Concept of Representation.Andreas Bartels - 2006 - Theoria: Revista de Teoría, Historia y Fundamentos de la Ciencia 21 (1):7-19.
    The aim of this paper is to defend the structural concept of representation, as defined by homomorphisms, against its main objections, namely: logical objections, the objection from misrepresentation, theobjection from failing necessity, and the copy theory objection. The logical objections can be met by reserving the relation ‘to be homomorphic to’ for the explication of potential representation (or, of the representational content). Actual reference objects (‘targets’) of representations are determined by (intentional or causal) representational mechanisms. Appealing to the independence of (...)
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  42.  35
    Defending the structural concept of representation.Andreas Bartels - 2006 - Theoria 21 (1):7-19.
    The paper defends the structural concept of representation, defined by homomorphisms, against the main objections that have been raised against it: Logical objections, the objection from misrepresentation, the objection from failing necessity, and the copy theory objection. Homomorphic representations are not necessarily ‘copies’ of their representanda, and thus can convey scientific insight.
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  43.  18
    Husserl's Transcendental Phenomenology: Nature, Spirit, and Life.Andrea Staiti - 2014 - New York: Cambridge University Press.
    Edmund Husserl is regarded as the founder of transcendental phenomenology, one of the major traditions to emerge in twentieth-century philosophy. In this book Andrea Staiti unearths and examines the deep theoretical links between Husserl's phenomenology and the philosophical debates of his time, showing how his thought developed in response to the conflicting demands of Neo-Kantianism and life-philosophy. Drawing on the work of thinkers including Heinrich Rickert, Wilhelm Dilthey and Georg Simmel, as well as Husserl's writings on the natural and (...)
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  44. Deserved Guilt and Blameworthiness over Time.Andreas Brekke Carlsson - 2022 - In Andreas Carlsson (ed.), Self-Blame and Moral Responsibility. New York, USA: Cambridge University Press.
  45. Shame and Attributability.Andreas Brekke Carlsson - 2019 - In David Shoemaker (ed.), Oxford Studies in Agency and Responsibility Volume 6. Oxford University Press.
    Responsibility as accountability is normally taken to have stricter control conditions than responsibility as attributability. A common way to argue for this claim is to point to differences in the harmfulness of blame involved in these different kinds of responsibility. This paper argues that this explanation does not work once we shift our focus from other-directed blame to self-blame. To blame oneself in the accountability sense is to feel guilt and feeling guilty is to suffer. To blame oneself in the (...)
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  46.  25
    Defending the structural concept of representation.Andreas Bartels - 2010 - Theoria 21 (1):7-19.
    The paper defends the structural concept of representation, defined by homomorphisms, against the main objections that have been raised against it: Logical objections, the objection from misrepresentation, the objection from failing necessity, and the copy theory objection. Homomorphic representations are not necessarily ‘copies’ of their representanda, and thus can convey scientific insight.
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  47. A dilemma for dispositional answers to Kripkenstein’s challenge.Andrea Guardo - 2023 - Minds and Machines 33 (1):135-152.
    Kripkenstein’s challenge is usually described as being essentially about the use of a word in new kinds of cases ‒ the old kinds of cases being commonly considered as non-problematic. I show that this way of conceiving the challenge is neither true to Kripke’s intentions nor philosophically defensible: the Kripkean skeptic can question my answering “125” to the question “What is 68 plus 57?” even if that problem is one I have already encountered and answered. I then argue that once (...)
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  48.  6
    Nichtwissen im Überfluss? Einige Präzisierungsvorschläge im Hinblick auf Nichtwissen und Technik.Andreas Kaminski - 2005 - In Gerhard Gamm (ed.), Unbestimmtheitssignaturen der Technik. Transcript Verlag. pp. 183-200.
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  49.  2
    Substanz Als Existenz Eine Philosophische Auslegung der Prote Ousia : Mit Text, ubersetzung und Diskussion von Aristoteles, Categoriae 1-5.Andrea Ermano - 2000 - New York: G. Olms.
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  50.  16
    Eine zeitgemäß-unzeitgemäße Philosophie der Technik.Andreas Hetzel & Gerhard Gamm - 2005 - In Gerhard Gamm (ed.), Unbestimmtheitssignaturen der Technik. Transcript Verlag. pp. 9-16.
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