Three experiments investigated the effect of rarity on people's selection and interpretation of data in a variant of the pseudodiagnosticity task. For familiar (Experiment 1) but not for arbitrary (Experiment 3) materials, participants were more likely to select evidence so as to complete a likelihood ratio when the initial evidence they received was a single likelihood concerning a rare feature. This rarity effect with familiar materials was replicated in Experiment 2 where it was shown that participants were relatively (...) insensitive to explicit manipulations of the likely diagnosticity of rare evidence. In contrast to the effects for data selection, there was an effect of rarity on confidence ratings after receipt of a single likelihood for arbitrary but not for familiar materials. It is suggested that selecting diagnostic evidence necessitates explicit consideration of the alternative hypothesis and that consideration of the possible consequences of the evidence for the alternative weakens the rarity effect in confidence ratings. Paradoxically, although rarity effects in evidence selection and confidence ratings are in the spirit of Bayesian reasoning, the effect on confidence ratings appears to rely on participants thinking less about the alternative hypothesis. (shrink)

It is often supposed that valuable organisms are more valuable if they are rare. Likewise if they belong to endangered species. I consider what kinds of value rarity and endangerment can add in such cases. I argue that individual organisms of a valuable species typically have instrumental value as means to the end of preserving their species. This progenitive value, I suggest, tends to increase exponentially with rarity. Endlings, for their part, typically have little progenitive value; however, I (...) argue that they may nonetheless have persistence value because, merely by existing, they postpone the numerical extinction of their species. Finally, I propose that a sentient endling can have higher lifeworld value than it would have had were it not the last of its kind. This, I argue, is because when a sentient endling dies, very little of its lifeworld is preserved – and this, I suggest, can be a bad thing. (shrink)

One feature of the individuals Nietzsche considers paradigms of greatness is that they are, in some capacity, rare —an exception to the majority.1 It would be difficult to overstate the frequency of this association in the texts. From as early as UM, Nietzsche repeatedly contrasts the “rarest and most valuable exemplars” with the pejorative “herd [Heerde]”, the “common [gemein]”, the “mediocre [mittelmässig]”, and the “rabble [Pöbel]”.2 This contrast becomes more explicit in Nietzsche’s mature period, where, for example, he writes plainly (...) that “what can be common has ever but little... (shrink)

The stunning possibility of “reprogramming” differentiated somatic cells to express a pluripotent stem cell phenotype (iPS, induced pluripotent stem cell) and the “ground state” character of pluripotency reveal fundamental features of cell fate regulation that lie beyond existing paradigms. The rarity of reprogramming events appears to contradict the robustness with which the unfathomably complex phenotype of stem cells can reliably be generated. This apparent paradox, however, is naturally explained by the rugged “epigenetic landscape” with valleys representing “preprogrammed” attractor states (...) that emerge from the dynamical constraints of the gene regulatory network. This article provides a pedagogical primer to the fundamental principles of gene regulatory networks as integrated dynamic systems and reviews recent insights in gene expression noise and fate determination, thereby offering a formal framework that may help us to understand why cell fate reprogramming events are inherently rare and yet so robust. (shrink)

“Situationists” such as Gilbert Harman and John Doris have accused virtue ethicists as having an “empirically inadequate” theory, arguing that much of social science research suggests that people do not have robust character traits as traditionally thought. By far, the most common response to this challenge has been what I refer to as “the rarity response” or the “rarity thesis”. Rarity responders deny that situationism poses any sort of threat to virtue ethics since there is no reason (...) to suppose that the moral virtues are typical or widespread. But, far from being its saving grace, I will argue, the rarity thesis forces virtue ethicists into positions that are incompatible with their theoretical foundations or render their theory normatively irrelevant. The more the virtue ethicists modify their thesis to fit the empirical evidence and to be normatively relevant, the less they retain a virtue ethical theory. This is also the case for virtue epistemologists. (shrink)

What is the Problem with the Rarity of the Virtues?An important strand of the situationist challenge to Aristotelian virtue ethics rests on the following claim:Rarity Thesis: On the basis of evidence from psychological research, we are justified in believing that possession of the Aristotelian virtues is very rare.The Rarity Thesis is sometimes regarded as a problem for virtue ethics, or as an embarrassing implication of claims made by virtue ethicists.See John Doris, Lack of Character (Cambridge, UK: Cambridge (...) University Press, 2002), 58–60, 110–112; John Doris and Stephen Stich, “As a Matter of Fact: Empirical Perspectives on Ethics” in The Oxford Handbook of Contemporary Philosophy (Oxford, UK: Oxford University Press, 2005), see esp. 120–123. Mark Alfano, Character as Moral Fiction (Cambridge, UK: Cambridge University Press, 2013). For the purposes of this essay, I will use “virtue ethics” to refer to broadly Aristotelian virtue ethics. However, as many people have pointed out, Ari. (shrink)

We introduce a ``rarity of defeat'' principle, valid in cases of deference to an expert, to address intuitions involved in a puzzle of Nissan-Rozen concerning epistemic deference and evidential screening-off.

Rare diseases pose a particular priority setting problem. The UK gives rare diseases special priority in healthcare priority setting. Effectively, the National Health Service is willing to pay much more to gain a quality-adjusted life-year related to a very rare disease than one related to a more common condition. But should rare diseases receive priority in the allocation of scarce healthcare resources? This article develops and evaluates four arguments in favour of such a priority. These pertain to public values, luck (...) egalitarian distributive justice the epistemic difficulties of obtaining knowledge about rare diseases and the incentives created by a higher willingness to pay. The first is at odds with our knowledge regarding popular opinion. The three other arguments may provide a reason to fund rare diseases generously. However, they are either overinclusive because they would also justify funding for many non-rare diseases or underinclusive in the sense of justifying priority for only some rare diseases. The arguments thus fail to provide a justification that tracks rareness as such. There are no data in this work. (shrink)

This article uses a core group of three arguments to support the contention that Yellowstone National Park's thermal sites deserve special efforts to preserve them, and that this goes above and beyond the general spirit motivating the national parks. It considers arguments having to do with educational value and rarity, and an argument that relies on aesthetic constructs. For purposes of evaluating the notion of rarity, comparison is made to work on the rare saline water preserve of Mono (...) Lake. Part and parcel of this line of debate has to do with the notion that there has been a general lack of commentary on the value of geothermal areas. The work of William J. Fritz and Robert C. Thomas, Marc Hendrix, and others is cited. (shrink)

Four classes of naturally rare vascular plant species are described and classified, based on parameters of spatial distribution and longevity. Properties intrinsic to these time/space parameters are explored and an importance hierarchy of causes of rarity is proposed for each class. These hierarchies serve as the basis for a predictive classification. Human causes of rarity such as habitat destruction and taxonomic difficulties are not considered in detail here but are discussed as confounding factors in the elucidation of (...) class='Hi'>rarity in vascular plants. Several examples are provided to illustrate this classification and provide testable hypotheses concerning the origins of natural rarity in plant species. (shrink)

This brief report raises the ethical dilemma encountered by an obstetrician involved in the care of a pregnant woman with life-threatening disease. This is a particularly difficult issue if the maternal well-being is in conflict with the survival of the unborn child.

The rarity of altruistic punishment in small-scale societies should not be interpreted as evidence that altruistic punishment is not an important determinant of cooperation in general. While it is essential to collect field data on altruistic punishment, this kind of data has limitations. Laboratory experiments can help shed light on the role of altruistic punishment.

Aristotle is a rarity in the history of philosophy and science - he is a towering figure in the history of both disciplines. Moreover, he devoted a great deal of philosophical attention to the nature of scientific knowledge. How then do his philosophical reflections on scientific knowledge impact his actual scientific inquiries? In this book James Lennox sets out to answer this question. He argues that Aristotle has a richly normative view of scientific inquiry, and that those norms are (...) of two kinds: a general, question-guided framework applicable to all scientific inquiries, and domain-specific norms reflecting differences in the target of inquiry and in the means of observation available to researchers. To see these norms of inquiry in action, the second half of this book examines Aristotle's investigations of animals, the soul, material compounds, the motions of heavenly bodies, and respiration. (shrink)

Thomas Kuhn is a rarity. Widely regarded as one of the most influential theorists of the physical sciences, he has also, largely through his concept of the ‘paradigm’, had a sustained effect on the social sciences and education. His classic The Structure of Scientific Revolutions is read and cited by scholars in an astonishing range of disciplines, in part due to its acquired association with progressive social research and practice. This article takes issue with Kuhn’s conceptions of science and (...) its translation into educational practice, and suggests that they do not deserve the warm embrace they have received. It is argued that Kuhn’s popularity among progressive thinkers is somewhat ironic, since his portrayal of ‘normal science education’ is inherently indoctrinatory, presenting insurmountable barriers to acceptance as part of a liberal educational philosophy. (shrink)

In recent years, several philosophers have used “situationist” findings in social psychology to criticize character-based ethical theories. After showing how these criticisms apply, prima facie, to Kant’s moral theory, I lay out a Kantian response to them. Kant admits the empirical reality of situation-dependence in human actions but articulates a conception of “ought implies can” that vindicates his character-based moral theory in the face of rarity of character. Moreover, he provides an interpretive framework for the situation-dependence of human motivation (...) in terms of humans’ “propensity to evil.” He also provides a framework for highlighting empirical bases for moral hope, a framework that makes it possible to see lack of character as something human beings can overcome. And he outlines a “moral anthropology” that develops something akin to what Mark Alfano calls “moral technologies,” but in Kant’s case, these technologies focus on cultivating character as such rather than merely good behavioral outcomes. (shrink)

The ability to convey our thoughts using an infinite number of linguistic expressions is one of the hallmarks of human language. Understanding the nature of the psychological mechanisms and representations that give rise to this unique productivity is a fundamental goal for the cognitive sciences. A long-standing hypothesis is that single words and rules form the basic building blocks of linguistic productivity, with multiword sequences being treated as units only in peripheral cases such as idioms. The new millennium, however, has (...) seen a shift toward construing multiword linguistic units not as linguistic rarities, but as important building blocks for language acquisition and processing. This shift—which originated within theoretical approaches that emphasize language learning and use—has far-reaching implications for theories of language representation, processing, and acquisition. Incorporating multiword units as integral building blocks blurs the distinction between grammar and lexicon; calls for models of production and comprehension that can accommodate and give rise to the effect of multiword information on processing; and highlights the importance of such units to learning. In this special topic, we bring together cutting-edge work on multiword sequences in theoretical linguistics, first-language acquisition, psycholinguistics, computational modeling, and second-language learning to present a comprehensive overview of the prominence and importance of such units in language, their possible role in explaining differences between first- and second-language learning, and the challenges the combined findings pose for theories of language. (shrink)

Contrary to the rarity of totipotent cells in animals, almost every cell formed by a fungus can function as a “stem cell”. The multicellular fruiting bodies of basidiomycete fungi consist of the same kind of filamentous hyphae that form the feeding phase, or mycelium, of the organism, and visible cellular differentiation is almost nonexistent. Mushroom primordia develop from masses of converging hyphae, and the stipe (or stem), cap, and gills are clearly demarcated within the embryonic fruiting body long before (...) the organ expands and unfolds through water uptake and cell wall loosening.aThough frequent references are made to gilled mushrooms in this article, the totipotent nature of fruiting body cells and lack of meristems is also applicable to basidiomycetes that spread their spore‐producing tissues inside tubes (e.g., boletes), over spines and rippled surfaces, or form spores in cavities within the fruiting body. Even in the mature mushroom, every hypha retains its totipotency. Among animals, only sponges exhibit a similar degree of developmental flexibility, which is interesting, because these simple metazoans may be relatively close relatives of fungi. BioEssays 24:949–952, 2002. © 2002 Wiley Periodicals, Inc. (shrink)

It has been reported as a robust effect that people are likely to select a matching case in the Wason selection task. For example, they usually select the 5 case, in the Wason selection task with the conditional "if an E, then a not-5". This was explained by the matching bias account that people are likely to regard a matching case as relevant to the truth of the conditional (Evans, 1998). However, because a positive concept usually constructs a smaller set (...) than its negative one does (a rarity assumption), it is more effective to get information on the truth of the conditional in a positive set than in a negative set. Thus the optimal data selection account can also explain the effect. The set size of Q and matching by introducing negation were manipulated independently in four experiments. From the results it was inferred that the so-called matching bias was an amalgam of two different cognitive components-relevance judgement by matching and optimal data selection. (shrink)

BackgroundThe Health Research Council of New Zealand is the first major government funding agency to use a lottery to allocate research funding for their Explorer Grant scheme. This is a somewhat controversial approach because, despite the documented problems of peer review, many researchers believe that funding should be allocated solely using peer review, and peer review is used almost ubiquitously by funding agencies around the world. Given the rarity of alternative funding schemes, there is interest in hearing from the (...) first cohort of researchers to ever experience a lottery. Additionally, the Health Research Council of New Zealand wanted to hear from applicants about the acceptability of the randomisation process and anonymity of applicants.MethodsThis paper presents the results of a survey of Health Research Council applicants from 2013 to 2019. The survey asked about the acceptability of using a lottery and if the lottery meant researchers took a different approach to their application.ResultsThe overall response rate was 39%, with 30% from applicants in the years 2013 to 2018, and 68% for those in the year 2019 who were not aware of the funding result. There was agreement that randomisation is an acceptable method for allocating Explorer Grant funds with 63% in favour and 25% against. There was less support for allocating funds randomly for other grant types with only 40% in favour and 37% against. Support for a lottery was higher amongst those that had won funding. Multiple respondents stated that they supported a lottery when ineligible applications had been excluded and outstanding applications funded, so that the remaining applications were truly equal. Most applicants reported that the lottery did not change the time they spent preparing their application.ConclusionsThe Health Research Council’s experience through the Explorer Grant scheme supports further uptake of a modified lottery. (shrink)

_ Source: _Volume 46, Issue 1, pp 35 - 53 In a letter written at the end of July 1930, Jean Cavaillès singled out two of his successful students at the _Ecole Normale_, Merleau-Ponty and Lautman, “full of interest in the philosophy of mathematics”. While both would play an important role in French philosophy in the coming decades, one almost never thinks of their names together. Indeed, only rarely do we think of Merleau-Ponty and Cavaillès together. This paper will argue (...) against this rarity. Cavaillès would write a treatise on logic that in retrospect is often viewed to advance French philosophy—but precisely at the expense phenomenology. I will argue that this evaluation is overblown. Merleau-Ponty’s philosophy, on the other hand, is often viewed in opposition to this as defending a Husserlian account of perception, a view equally too narrow. Between them, instead, I argue, we can see both transforming the Husserlian account of a transcendental logic and a transcendental aesthetic. Both provide resources for understanding phenomenology as a dialectical and historically emergent theory. Notwithstanding Cavaillès initial characterization of Husserl’s “exhorbitant use of the Cogito”, or his “aggressive” description of acts, to use Merleau-Ponty’s term, the result, in both cases, focuses on phenomenology as an emergent experience of philosophy as an “architecture” of signs. (shrink)

This book is a rarity in the currently popular "physics-for-poets" genre insofar as it has a legitimate claim to the interests of metaphysicians and philosophers of science. The author is a veteran scholar who has achieved the unusual combination of professional respectability and commercial success. Although the nonscientific reader may at first be intimidated by the book's clutter of technical jargon, and although readers from all backgrounds may be annoyed by Comfort's compressed style and faddish language, colloquialisms, and mixed (...) metaphors, the text is still quite readable, both since Comfort has provided a useful glossary of technical terms and since his presentation, while difficult in both form and content, is often witty and provocative--and never dull. But one who likes this book could also reasonably be expected to like Finnegan's Wake. (shrink)

Syntactic complexity effects have been investigated extensively with respect to comprehension . According to one prominent class of accounts , certain structures cause comprehension difficulty due to their scarcity in the language. But why are some structures less frequent than others? In two elicited-production experiments we investigated syntactic complexity effects in relative clauses and wh-questions varying in whether or not they contained non-local dependencies. In both experiments, we found reliable durational differences between subject-extracted structures and object-extracted structures : Participants took (...) longer to begin and produce object-extractions. Furthermore, participants were more likely to be disfluent in the object-extracted constructions. These results suggest that there is a cost associated with planning and uttering the more syntactically complex, object-extracted structures, and that this cost manifests in the form of longer durations and disfluencies. Although the precise nature of this cost remains to be determined, these effects provide one plausible explanation for the relative rarity of object-extractions: They are more costly to produce. (shrink)

It’s natural to assume that the bearers of virtues are individual agents, which would make virtues monadic dispositional properties. I argue instead that the most attractive theory of virtue treats a virtue as a triadic relation among the agent, the social milieu, and the asocial environment. A given person may or may not be disposed to behave in virtuous ways depending on how her social milieu speaks to and of her, what they expect of her, and how they monitor her. (...) Likewise, asocial environmental factors such as mood elevators, mood depressors, ambient sounds, and ambient smells mediate morally important behavioral dispositions. Many commentators have responded to such intrusions from outside the agent by arguing for the rarity of virtue understood as a monadic property. In contrast, I claim that we need to rethink the very nature of virtue, which would entail that cultivating virtue can be accomplished not only by habituation and other such interventions on the individual agent but also by selecting, modifying, and reinterpreting the social and asocial aspects of the environment. (shrink)

We present a theoretical framework bearing on the evolution of written communication. We analyze writing as a special kind of graphic code. Like languages, graphic codes consist of stable, conventional mappings between symbols and meanings, but (unlike spoken or signed languages) their symbols consist of enduring images. This gives them the unique capacity to transmit information in one go across time and space. Yet this capacity usually remains quite unexploited, because most graphic codes are insufficiently informative. They may only be (...) used for mnemonic purposes or as props for oral communication in real-time encounters. Writing systems, unlike other graphic codes, work by encoding a natural language. This allows them to support asynchronous communication in a more powerful and versatile way than any other graphic code. Yet, writing systems will not automatically unlock the capacity to communicate asynchronously. We argue that this capacity is a rarity in non-literate societies, and not so frequent even in literate ones. Asynchronous communication is intrinsically inefficient because asynchrony constrains the amount of information that the interlocutors share and limits possibilities for repair. This would explain why synchronous, face-to-face communication always fosters the development of sophisticated codes (natural languages), but similar codes for asynchronous communication evolve with more difficulties. It also implies that writing cannot have evolved, at first, for supporting asynchronous communication. (shrink)

Given that natural selection is so powerful at optimizing complex adaptations, why does it seem unable to eliminate genes (susceptibility alleles) that predispose to common, harmful, heritable mental disorders, such as schizophrenia or bipolar disorder? We assess three leading explanations for this apparent paradox from evolutionary genetic theory: (1) ancestral neutrality (susceptibility alleles were not harmful among ancestors), (2) balancing selection (susceptibility alleles sometimes increased fitness), and (3) polygenic mutation-selection balance (mental disorders reflect the inevitable mutational load on the thousands (...) of genes underlying human behavior). The first two explanations are commonly assumed in psychiatric genetics and Darwinian psychiatry, while mutation-selection has often been discounted. All three models can explain persistent genetic variance in some traits under some conditions, but the first two have serious problems in explaining human mental disorders. Ancestral neutrality fails to explain low mental disorder frequencies and requires implausibly small selection coefficients against mental disorders given the data on the reproductive costs and impairment of mental disorders. Balancing selection (including spatio-temporal variation in selection, heterozygote advantage, antagonistic pleiotropy, and frequency-dependent selection) tends to favor environmentally contingent adaptations (which would show no heritability) or high-frequency alleles (which psychiatric genetics would have already found). Only polygenic mutation-selection balance seems consistent with the data on mental disorder prevalence rates, fitness costs, the likely rarity of susceptibility alleles, and the increased risks of mental disorders with brain trauma, inbreeding, and paternal age. This evolutionary genetic framework for mental disorders has wide-ranging implications for psychology, psychiatry, behavior genetics, molecular genetics, and evolutionary approaches to studying human behavior. (Published Online November 9 2006) Key Words: adaptation; behavior genetics; Darwinian psychiatry; evolution; evolutionary genetics; evolutionary psychology; mental disorders; mutation-selection balance; psychiatric genetics; quantitative trait loci (QTL). (shrink)

Since 1923 the Sammlung Tusculum has published authoritative editions of Greek and Latin works together with a German translation. The original texts are comprehensively annotated, and feature an introductory chapter. In the new volumes, additional essays delve into specific aspects of the works, illuminating their historical context and reception to the present day. The high academic quality of the new editions together with clearly written essays and annotations make the Sammlung Tusculum essential reading for students who are discovering an ancient (...) author for the first time as well as professional scholars who would like to gain a deeper understanding of specific aspects of a given work. Moreover, the series is ideal for lay readers who would like to engage with antiquity through a reliable German translation. The series contains over 270 titles, available in print and eBook editions, making previously out-of-print titles and rarities available again for the first time. In order to celebrate the 90th anniversary of the series, De Gruyter is proud to present Tusculum Online, an eBook package which contains all titles that appeared between 1923 and 2013 - a fitting tribute to an important part of German publishing history. For more information, please see www.degruyter.com/tusculum. (shrink)

Since 1923 the Sammlung Tusculum has published authoritative editions of Greek and Latin works together with a German translation. The original texts are comprehensively annotated, and feature an introductory chapter. In the new volumes, additional essays delve into specific aspects of the works, illuminating their historical context and reception to the present day. The high academic quality of the new editions together with clearly written essays and annotations make the Sammlung Tusculum essential reading for students who are discovering an ancient (...) author for the first time as well as professional scholars who would like to gain a deeper understanding of specific aspects of a given work. Moreover, the series is ideal for lay readers who would like to engage with antiquity through a reliable German translation. The series contains over 270 titles, available in print and eBook editions, making previously out-of-print titles and rarities available again for the first time. In order to celebrate the 90th anniversary of the series, De Gruyter is proud to present Tusculum Online, an eBook package which contains all titles that appeared between 1923 and 2013 - a fitting tribute to an important part of German publishing history. For more information, please see www.degruyter.com/tusculum. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Standing UpEmily QuinnA 10–year old and her mother walk into a male gynecologist’s office. That sounds like the beginning of a sick joke, right? Imagine how it must have felt to actually be that 10–year–old. I walked into the Salt Lake City ob–gyn office, terrified out of my mind. It was the year 1999 and due to the recent accessibility of the Internet, there was a surprising amount of (...) information about complete androgen insensitivity syndrome (CAIS) available. There was also an active and prominent support group for women with CAIS and other similar conditions. Despite all of this, I was standing in the office of a doctor who knew nothing about my body. He did not direct me to any actual support, and for the next twelve years I went from doctor to doctor, none of them really knowing what to do with me. For as much as I was in and out of the doctor’s office, I never seemed to receive any “care.”It was really difficult to have doctors who knew nothing about my condition. It was scary to be a kid with hundreds of questions but without an adult who had the answers. So many doctors were excited to look at me, to talk to me, to get the chance to meet me. As a child it made me feel like a freak. I felt alone, and scared, like I was on parade for all of these people who didn’t know anything about me except that I was “special.”I was savvy enough to turn to the Internet for help, but searching for “sex disorders” online was a terrifying thing to do back then. Even now, it’s not a safe space for a pre–teen looking for answers. I was so scared and ashamed of my body, and I desperately wanted someone to talk to about it. I found articles about celebrities who were rumored to be like me, and I saw the word “hermaphrodite” thrown around as carelessly as it had been used in my doctor’s office. I wished desperately that one of those celebrities would admit to having a body like mine. Because if any of them were like me, maybe I wouldn’t be the freak that the adults made me feel like I was. Maybe then I wouldn’t be so alone.As hard as all of this was, in a way my doctor’s lack of knowledge turned out to be both a blessing and a curse. I felt cursed and ashamed of this different, “broken” body that couldn’t be “fixed.” I felt like a problem that nobody had the solution to. I was told so many lies—that I would definitely get cancer, that I could never have sex, that I needed surgery immediately. Not once was I ever told the truth—that there were hundreds of others out there I could talk to, that I didn’t do anything wrong, that I was going to be okay. My doctors didn’t point me in the direction of a support group or a therapist who could help me work through what it all meant. In Utah, the most important thing a woman can do is to have children, and it was devastating to learn I would not to be able to conceive. I wish any of my doctors had pointed me in the direction of a professional I could talk to about it.It wasn’t until I was older that I discovered the blessing amongst all of this pain. As it turns out, my doctors were so entirely ignorant about my condition that they didn’t know how to remove or even find my internal testes. I’ve managed to make it 25 years without surgery. Now, when I speak to medical students, many of them balk at this idea that surgery is something I’ve “escaped.” But I know how many affected individuals see it as I do. It’s incredibly lucky that somebody with CAIS is surgically untouched, and I fully believe that rarity to be the saddest thing. It shouldn’t be the norm to... (shrink)

Forensic evidence often involves an evaluation of whether two impressions were made by the same source, such as whether a fingerprint from a crime scene has detail in agreement with an impression taken from a suspect. Human experts currently outperform computer-based comparison systems, but the strength of the evidence exemplified by the observed detail in agreement must be evaluated against the possibility that some other individual may have created the crime scene impression. Therefore, the strongest evidence comes from features in (...) agreement that are also not shared with other impressions from other individuals. We characterize the nature of human expertise by applying two extant metrics to the images used in a fingerprint recognition task and use eye gaze data from experts to both tune and validate the models. The Attention via Information Maximization model quantifies the rarity of regions in the fingerprints to determine diagnosticity for purposes of excluding alternative sources. The CoVar model captures relationships between low-level features, mimicking properties of the early visual system. Both models produced classification and generalization performance in the 75%–80% range when classifying where experts tend to look. A validation study using regions identified by the AIM model as diagnostic demonstrates that human experts perform better when given regions of high diagnosticity. The computational nature of the metrics may help guard against wrongful convictions, as well as provide a quantitative measure of the strength of evidence in casework. (shrink)

The word euboulia, which means excellence in counsel or sound judgement, occurs in only three places in the authentic writings of Plato. The sophist Protagoras makes euboulia the focus of his whole enterprise : What I teach a person is good judgement about his own affairs — how best he may manage his own household; and about the affairs of the city — how he may be most able to handle the business of the city both in action and in (...) speech. Thrasymachus, too, thinks well of euboulia. Invited by Socrates to call injustice kakoetheia ’, i.e. as simple-mindedness), he declines the sophistry and says : ‘No, I call it good judgement’. But Plato finds little occasion to introduce the concept in developing his own ethical and political philosophy. The one place where he mentions euboulia is in his defence of the thesis that his ideal city possesses the four cardinal virtues. He begins with wisdom, and justifies the ascription of wisdom to the city on the ground that it has euboulia — which he goes on to identify with the knowledge required by the guardians: ‘with this a person does not deliberate on behalf of any of the elements in the city, but for the whole city itself — how it may best have dealings with itself and with the other cities’ . It is normally rather dangerous to draw an inference from the absence or rarity of a word to the absence or rarity of the idea expressed by the word. (shrink)

Orphan drug policy often gives ‘special treatment’ to rare diseases, by giving additional priority or making exceptions to specific drugs, based on the rarity of the conditions they aim to treat. This essay argues that the goal of orphan drug policy should be to make prevalence irrelevant to funding decisions. It aims to demonstrate that it is severity, not prevalence, which drives our judgments that important claims are being overlooked when treatments for severe rare diseases are not funded. It (...) shows that prioritising severity avoids problems caused by prioritising rarity, and that it is compatible with a range of normative frameworks. The implications of a severity-based view for drug development are then derived. The severity-based view also accounts for what is wrong with how the current system of drug development unfairly neglects common diseases that burden the developing world. Lastly, the implications of a severity-based view for current orphan drug policies are discussed. There are no data in this work. (shrink)

In the present manuscript, we comment upon a paper that strongly criticized an expert report written by the consultants of the defense in a case of pedophilia, in which clinical and neuro-scientific data were used to establish the causal link between brain alterations and onset of criminal behavior. These critiques appear to be based mainly on wrong pieces of information and on a misinterpretation of the logical reasoning adopted by defense consultants. Here we provide a point-by-point reply to the issues (...) raised in the above paper and also discuss the potential role that neuroscience may contribute in the forensic context. Did the forensic neuroscience defense consultants claim the existence of a deterministic relationship between brain structure or function and behavior? How did the neuroscientific logic work in this specific case? How may the classic psychiatric/neurologic examination and neuroscientific evidence work side by side? Does the rarity of a disease impact on the causal relationship between the disease and the crime? Do neuroscientific data need to be interpreted? We address the above questions and conclude that neuroscience may strengthen the results of psychiatric evaluations, thus reducing uncertainty in the forensic settings. (shrink)

To what extent do I have a sense of agency over my thoughts while I dream? The sense of agency in dreams can alter in a variety of interesting ways distinct from normal, waking experience. In fact, dreams show many similarities to the experiences of individuals with schizophrenia. In this paper I analyze these alterations with a focus on distinguishing between reduced sense of agency and other cognitive features such as metacognition, confabulation and attention. I argue that some dream reports (...) demonstrate two interesting commonalities with schizophrenia: thought insertion (TI) and auditory hallucination (AH). This line of research has the potential to further our understanding of TI and AH in schizophrenia through the analysis of similar experience in a different conscious state. Through the analysis of dream reports, I found that although TI and AH both occur in dreams, TI is very rare. This is an interesting result since TI is common in patients with schizophrenia. I propose two speculative lines of explanation for the rarity of TI in dreams: first, the cognitive differences between the symptoms of schizophrenia and dreams, and second, the problem of dream reporting conditions. Dream reporting conditions are particularly important, as without controls, reports can be vague. Analysis of dream reports reveals that it is often unclear whether 'hearing voices' indicates sound phenomenology or thought phenomenology. I propose that dream reports could be disambiguated given the right experimental conditions and I suggest how this could be achieved in future experimental research. (shrink)

This book conveys the breadth and interconnectedness of questions of justice - a rarity in contemporary moral and political philosophy. James P. Sterba argues that a minimal notion of rationality requires morality, and that a minimal libertarian morality requires the welfare and equal opportunity endorsee by welfare liberals and the equality endorsed by socialists, as well as a full feminist agenda. Feminist, racial, homosexual, and multicultural justice, are also shown to be mutually supporting. The author further shows the compatibility (...) between anthropocentric and biocentric environmental ethics, as between just war and pacifist theories. Finally, he spells out when normal politics, legal protest, civil disobedience, revolutionary action, and criminal disobedience are morally permitted by justice for here and now. This highly original and potentially controversial book is ideal for courses in moral and political philosophy, applied ethics, women's studies, environmental studies, and peace studies. (shrink)

The acquisition of genetic information (GI) confronts both the affected individuals and healthcare providers with difficult, ambivalent decisions. Genetic responsibility (GR) has become a key concept in both ethical and socioempirical literature addressing how and by whom decision-making with respect to the morality of GI is approached. However, despite its prominence, the precise meaning of the concept of GR remains vague. Therefore, we conducted a systematic literature review on the usage of the concept of GR in qualitative, socioempirical studies, to (...) identify the main interpretations and to provide conceptual clarification. The review identified 75 studies with primarily an Anglo-American setting. The studies focused on several agents: the individual, the family, the parent, the healthcare professional, and the institution and refer to the concept of GR on the basis of either a rational/principle-oriented approach or an affective/relational approach. A subtype of the rational/principle-oriented approach is the reactive approach. The review shows how the concept of GR is useful for analyzing and theorizing about socioempirical findings within qualitative socioempirical studies and also reveals conceptual deficits in terms of insufficient theoretical accuracy and heterogeneity, and in the rarity of reflection on cultural variance. The vagueness and multiplicity of meanings for GR in socioempirical studies can be avoided by more normative-theoretical explication of the underlying premises. This would provide a higher degree of differentiation of empirical findings. Thereby, the complex findings associated with the individual and social implications of genetic testing in empirical studies can be better addressed from a theoretical point of view and can subsequently have a stronger impact on normative and policy debates. (shrink)

The wordeuboulia, which meansexcellence in counselorsound judgement, occurs in only three places in the authentic writings of Plato. The sophist Protagoras makeseubouliathe focus of his whole enterprise(Prot.318e–319a):What I teach a person is good judgement about his own affairs — how best he may manage his own household; and about the affairs of the city — how he may be most able to handle the business of the city both in action and in speech.Thrasymachus, too, thinks well ofeuboulia. Invited by Socrates (...) to call injusticekakoetheia(vicious disposition — he has just identified justice as ‘an altogether noble good nature (euetheia)’, i.e. as simple-mindedness), he declines the sophistry and says (Rep. 348d): ‘No, I call it good judgement’. But Plato finds little occasion to introduce the concept in developing his own ethical and political philosophy. The one place where he mentionseubouliais in his defence of the thesis that his ideal city possesses the four cardinal virtues. He begins with wisdom, and justifies the ascription of wisdom to the city on the ground that it haseuboulia(Rep.428b) — which he goes on to identify with the knowledge required by the guardians: ‘with this a person does not deliberate on behalf of any of the elements in the city, but for the whole city itself — how it may best have dealings with itself and with the other cities’ (428c–d). It is normally rather dangerous to draw an inference from the absence or rarity of a word to the absence or rarity of the idea expressed by the word. (shrink)

When aggression is conceptualised in terms of a cost-benefit ratio, sex differences are best understood by a consideration of female costs as well as male benefits. Benefits must be extremely high to outweigh the greater costs borne by females, and circumstances where this occurs are discussed. Achievement of dominance is not such a circumstance and evidence bearing upon women's egalitarian relationships is reviewed. Attempts to explain sex differences in terms of sexual dimorphism, sex-of-target effects, social control, and socialisation are found (...) to be inadequate. The suggestion that the stigmatisation of female aggreession arises not from patriarchal imposition but from statistical rarity (resulting from evolutionary pressures) is given serious consideration. Two hypotheses (“internal read-out” versus social/epidemiological representations) are described to explain the relationship between sex differences in behaviour and corresponding lay explanations. (shrink)

Is blue food desirable or disgusting? The answer, it would seem, is both, but it really depends on the food in which the color happens to be present. It turns out that the oft-cited aversive response to blue meat may not even have been scientifically validated, despite the fact that blue food coloring is often added to discombobulate diners. In the case of drinks, however, there has been a recent growth of successful new blue product launches in everything from beer (...) to tea, and from wine to gin, arguing that coloring food products blue is more than simply a contemporary fad. In fact, the current interest in blue food coloring builds on the color's earlier appearance in everything from blue curacao to blue-raspberry candyfloss, and thereafter a number of soft drinks. Over the years, the combination of blue coloring with raspberry flavoring has also appeared in everything from bubble-gum to patriotic pop rocks. Ultimately, it is the rarity of naturally-blue foods that is likely what makes this color so special. As such, blue food coloring can both work effectively to attract the visual attention of the shopper while, at the same time, being linked to a range of different flavors depending on the food format in which it happens to appear. Note also that the basic descriptor “blue” covers a wide range of hues having a range of different associations, hence eliciting different reactions. While blue was once associated with artificiality, a growing number of natural blue food colorings have come onto the market in recent years thus perhaps changing the dominant associations that many consumers may have with this most unusual of food colors. (shrink)

Longtermism is the thesis that in a large class of decision situations, the best thing we can do is what is best for the long-term future. The scope question for longtermism asks: how large is the class of decision situations for which this is true? In this paper, I suggest that the scope of longtermism may be narrower than many longtermists suppose. I identify a restricted version of longtermism: swamping axiological strong longtermism (swamping ASL). I identify three scope-limiting factors - (...) probabilistic and decision-theoretic phenomena which, when present, tend to reduce the prospects for swamping ASL. I argue that these scope-limiting factors are often present in human decision problems, then use two case studies from recent discussions of longtermism to show how the scope-limiting factors lead to a restricted, if perhaps nonempty, scope for swamping ASL. (shrink)

In this article, 41 models of covariation detection from 2 × 2 contingency tables were evaluated against past data in the literature and against data from new experiments. A new model was also included based on a limiting case of the normative phi‐coefficient under an extreme rarity assumption, which has been shown to be an important factor in covariation detection (McKenzie & Mikkelsen, 2007) and data selection (Hattori, 2002; Oaksford & Chater, 1994, 2003). The results were supportive of the (...) new model. To investigate its explanatory adequacy, a rational analysis using two computer simulations was conducted. These simulations revealed the environmental conditions and the memory restrictions under which the new model best approximates the normative model of covariation detection in these tasks. They thus demonstrated the adaptive rationality of the new model. (shrink)

In the ancient world, precious stones (valuable stones and hard substances excluding gold, silver and copper) were distinguished in terms of appearance (beauty, colour), function (durability) and cost (rarity). As a result, there is considerable difficulty in determining how to correlate the inventory of lexical terms referring to precious stones in the ancient Near East with modern mineralogical identifications. In this article, the etymology and identification of precious stones in the Bible are revisited using editorial theory and complexity thinking. (...) The starting point for lexicographical identification is the breastpiece of the high priest (Ex 28:17–20; 39:10–14) with its 12 precious stones and the translation of the Hebrew terms in the Septuagint. In the light of the considerable writings in the Hellenistic world on precious stones, especially Pliny’s Naturalis Historia and Theophrastus’ On Stones, the Septuagint provides the key for the etymology and identification of the precious stones in both the Old Testament and the New Testament. Contribution: The Septuagint translation of the precious stones in the high priest’s breastpiece is the Rosetta Stone for the identification all of the precious stones in the Hebrew Bible and New Testament. The subsequent translations of the terms indicate changes or substitutions of referents and their meanings. (shrink)

It is intuitively plausible that not every evildoer is an evil person. In order to make sense of this intuition we need to construct an account of evil personhood in addition to an account of evil action. Some philosophers have offered aggregative accounts of evil personhood, but these do not fit well with common intuitions about the explanatory power of evil personhood, the possibility of moral reform, and the relationship between evil and luck. In contrast, a dispositional account of evil (...) personhood can allow that evil is explanatory, that an evil person can become good, and that luck might prevent evil persons from doing evil or cause non-evil persons to do evil. Yet the dispositional account of evil personhood implies that some evil persons are blameless, which seems to clash with the intuition that evil persons deserve our strongest moral condemnation. Moreover, since it is likely that a large proportion of us are disposed to perform evil actions in some environments, the dispositional account threatens to label a large proportion of people evil. In this paper I consider a range of possible modifications to the dispositional account that might bring it more closely into alignment with our intuitions about moral condemnation and the rarity of evil persons. According to the most plausible of these theories, S is an evil person if S is strongly disposed to perform evil actions when in conditions that favour S's autonomy. (shrink)

This study examines the influence of auditor-CEO surname sharing on financial misstatement and further investigates whether the above effect depends on hometown relationship and the rarity of surnames, respectively. Using hand-collected data from China, the findings show that ACSS is significantly positively related to financial misstatement, suggesting that the auditor-CEO ancestry membership elicits the collusion and increases the likelihood of financial misstatement. Moreover, ACSS based upon hometown relationship leads to significantly higher likelihood of financial misstatement, compared with ACSS without (...) hometown relationship. Furthermore, the positive relation between ACSS and financial misstatement is more pronounced for rare surnames than for common surnames. The above findings are robust to sensitivity tests on the basis of different measures of ACSS and financial misstatement, and my conclusions are still valid after using the propensity score matching approach to address the endogeneity concerns. (shrink)