" Vivid . . . immense clarity . . . the product of a brilliant and extremely forceful intellect." — Journal of the Royal Naval Scientific Service "Still a sheer joy to read." — Mathematical Gazette "Should be read by any student, teacher or researcher in mathematics." — Mathematics Teacher The originator of algebraic topology and of the theory of analytic functions of several complex variables, Henri Poincare (1854–1912) excelled at explaining the complexities of scientific and mathematical ideas to (...) lay readers. Science and Method, written in 1908, has been appreciated by a wide audience of nonprofessionals and translated into many languages. It defines the basic methodology and psychology of scientific discovery, particularly in regard to mathematics and mathematical physics. Drawing on examples from many fields, it explains how scientists analyze and choose their working facts, and it explores the nature of experimentation, theory, and the mind. 1914 edition. Translated by Francis Maitland. (shrink)

THE VALUE OF SCIENCE INTRODUCTION The search for truth should be the goal of our activities; it is the sole end worthy of them. Doubtless we should first bend our efforts to assuage human suffering, but why ? Not to suffer is a negative ...

Henri Lefebvre has considerable claims to be the greatest living philosopher. His work spans some sixty years and includes original work on a diverse range of subjects, from dialectical materialism to architecture, urbanism and the experience of everyday life. The Production of Space is his major philosophical work and its translation has been long awaited by scholars in many different fields. The book is a search for a reconciliation between mental space and real space. In the course of his (...) exploration, Henri Lefebvre moves from metaphysical and ideological considerations of the meaning of space to its experience in the everyday life of home and city. He seeks, in other words, to bridge the gap between the realms of theory and practice, between the mental and the social, and between philosophy and reality. In doing so, he ranges through art, literature, architecture and economics, and further provides a powerful antidote to the sterile and obfuscatory methods and theories characteristic of much recent continental philosophy. This is a work of great vision and incisiveness. It is also characterized by its author's wit and by anecdote, as well as by a deftness of style which Donald Nicholson-Smith's sensitive translation precisely captures. (shrink)

A monumental work by an important modern philosopher, Matter and Memory (1896) represents one of the great inquiries into perception and memory, movement and time, matter and mind. Nobel Prize-winner Henri Bergson surveys these independent but related spheres, exploring the connection of mind and body to individual freedom of choice. Bergson’s efforts to reconcile the facts of biology to a theory of consciousness offered a challenge to the mechanistic view of nature, and his original and innovative views exercised a (...) profound influence on other philosophers--including James, Whitehead, and Santayana--as well as novelists such as Dos Passos and Proust. Matter and Memory is essential to an understanding of Bergson’s philosophy and its legacy. (shrink)

-- v. 3. From modernity to modernism (towards a metaphilosophy of daily life).

The possibility of employing human enhancement interventions to aid in future space missions has been gaining attention lately. These possibilities have included one of the more controversial kinds of enhancements: biomedical moral enhancement. However, the discussion has thus far remained on a rather abstract level. In this paper we further this conversation by looking more closely at what type of interventions with what sort of effects we should expect when we are talking about biomedical moral enhancements. We suggest that a (...) more grounded way to picture moral enhancement, at least in the near term, is to envision a form of cognitive enhancement that also provides some moral benefits by heightening the enhanced person's capability for acting according to their own subjective moral code. While this concept of moral adherence enhancement also has relevance for the moral enhancement discussion more widely, in this paper we apply it specifically in the context of space missions. We argue that there are weighty reasons to consider making biomedical enhancements of the proposed kind a mandatory feature of early-phase long-distance space travel because these missions are high-stakes in nature and take place in an environment where the enhancement could be seen as conferring important advantages while negating many of the traditional arguments weighed against it. (shrink)

This paper assesses the prospects of combining the distinctive strengths of the two major educational research programs of critical thinking and critical pedagogy—or, described more accurately, overcoming their shared limitations—in a new and superior educational objective called criticality. Several recent proposals explore the possibilities of engaging in bridge-building between these camps. The plan is that the distinctive strengths of these paradigms—the logical and epistemological precision of critical thinking together with the socio-political consciousness of critical pedagogy—could complement each other, while the (...) associated adjustments to the overall picture could also help us to address their shared shortcomings. This gives us a new and more grounded educational goal of criticality, as suggested and developed independently by a growing number of thinkers. This article joins the ongoing conversation but provides a more counterreactionary tone by striving to vindicate the traditional mainstream conception of critical thinking. I maintain that despite their admirable ambitions, the various expressions of criticality do not succeed in combining the best parts of critical thinking and critical pedagogy, since on a deep metatheoretical level these two paradigms have irreconcilable core principles. First, I argue that the depiction of the failures of critical thinking used to motivate criticality is to a large degree a straw man: in actuality, the existing conceptualization of critical thinking can already do the desired extra socio-political educational work, so there really is no pressing need for the suggested augmentations. Second, the traditional worries of indoctrination, which have followed critical pedagogy since the inception of this educational movement, still remain unresolved within criticality. The only way to address this concern successfully is to lean on critical thinking as the core of our educational theory, bringing us right back to where we started. (shrink)

One of the requirements in the Dutch regulation for euthanasia and assisted suicide is that the doctor must be satisfied ‘that the patient's suffering is unbearable, and that there is no prospect of improvement.’ In the notorious Chabot case, a psychiatrist assisted a 50 year old woman in suicide, although she did not suffer from any somatic disease, nor strictly speaking from any psychiatric condition. In Seduced by Death, Herbert Hendin concluded that apparently the Dutch regulation now allows physicians to (...) assist anyone in suicide simply because he or she is unhappy.In this paper, I reject Hendin's conclusion and in particular his description of Mrs Boomsma as someone who was ‘simply unhappy.’ After a detailed narration of her lifestory, I turn to the American philosopher Harry Frankfurt's account of volitional incapacity and love for a more accurate characterization of her suffering. Having been through what she had, she could only go on living as another person than the one she had been when she was a happy mother. That would have violated her integrity, and that she could not bring herself to do. (shrink)

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain (...) in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

BackgroundSince 2006, the genetic testing company 23andMe has collected biological samples, self-reported information, and consent documents for biobanking and research from more than 1,000,000 individuals, through a direct-to-consumer online genetic-testing service providing a genetic ancestry report and a genetic health report. However, on November 22, 2013, the Food and Drug Administration halted the sale of genetic health testing, on the grounds that 23andMe was not acting in accordance with federal law, by selling tests of undemonstrated reliability as predictive tests for (...) medical risk factors. Consumers could still obtain the genetic ancestry report, but they no longer had access to the genetic health report in the United States. However, this did not prevent the company from continuing its health research, with previously obtained and future samples, provided that consent had been obtained from the consumers concerned, or with health reports for individuals from other countries. Furthermore, 23andMe was granted FDA authorization on February 19, 2015, first to provide reports about Bloom syndrome carrier status, and, more recently, to provide consumers with “carrier status” information for 35 genes known to cause disease.DiscussionIn this Debate, we highlight the likelihood that the primary objective of the company was probably two-fold: promoting itself within the market for predictive testing for human genetic diseases and ancestry at a low cost to consumers, and establishing a high-value database/biobank for research and personal information).SummaryBy dint of this marketing approach, a two-sided market has been established between the consumer and the research laboratories, involving the establishment of a database/DNA biobank for scientific and financial gain. We describe here the profound ethical issues raised by this setup. (shrink)

Most human societies have undergone much greater change over the last few decades, or even years, than in the preceding millennia. This is partly due to the emergence of various phenomena in medici...

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in (...) the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

Networks for the exchange and/or sharing of genetic data are developing in many countries. We focus here on the situations in the US and France. We highlight some recent and remarkable differences between these two countries concerning the mode of access to, and the storage and use of genetic data, particularly as concerns two-sided markets and dynamic consent or dynamic electronic informed consent. This brief overview suggests that, even though the organization and function of these two-sided markets remain open to (...) criticism, dynamic e-IC should be more widely used, especially in France, if only to determine its real effectiveness. (shrink)

HENRI BERGSON (1859-1941), philosophe français, professeur au Collège de France de 1900 jusqu´à 1921, récompensé avec le prix Nobel de littérature en 1928. Ses oeuvres majeures, écrites avec un style parfaitement accessible au lecteur non spécialisé, sont : « Essai sur les données immédiates de la conscience » (1889), « Matière et mémoire » (1896), « L´évolution créatrice » (1907) et « Les deux sources de la morale et de la religion » (1932). Dans ces études, Bergson élabore une (...) vision philosophique en opposition au matérialisme et positivisme scientifique. Concentrant sa recherche sur les intuitions individuelles, il prône la notion d´élan vital, lequel dirige le procès évolutif vers des états d´organisation de plus en plus complexes, et de là vient l´intérêt de donner prééminence à tout ce qui est spirituel et ouvertement créatif, sur tout ce qui est formel, fixé, fermé. Dans « Le rire : essai sur la signification du comique » (1900), il trouve que le comique est soulevé des que nous percevons dans les actions humaines les automatismes, répétitions ou dysfonctionnements qui contrastent avec l´essentielle spontanéité de la vie réelle. (shrink)

HENRI BERGSON (1859-1941), philosophe français, professeur au Collège de France de 1900 jusqu´à 1921, récompensé avec le prix Nobel de littérature en 1928. Ses oeuvres majeures, écrites avec un style parfaitement accessible au lecteur non spécialisé, sont : « Essai sur les données immédiates de la conscience » (1889), « Matière et mémoire » (1896), « L´évolution créatrice » (1907) et « Les deux sources de la morale et de la religion » (1932). Dans ces études, Bergson élabore une (...) vision philosophique en opposition au matérialisme et positivisme scientifique. Concentrant sa recherche sur les intuitions individuelles, il prône la notion d´élan vital, lequel dirige le procès évolutif vers des états d´organisation de plus en plus complexes, et de là vient l´intérêt de donner prééminence à tout ce qui est spirituel et ouvertement créatif, sur tout ce qui est formel, fixé, fermé. Dans « Le rire : essai sur la signification du comique » (1900), il trouve que le comique est soulevé des que nous percevons dans les actions humaines les automatismes, répétitions ou dysfonctionnements qui contrastent avec l´essentielle spontanéité de la vie réelle. (shrink)

The practice and development of modern medicine requires large amounts of data, particularly in the domain of cancer. The future of personalized medicine lies neither with “genomic medicine” nor with “precision medicine”, but with “data medicine”. The establishment of this DM has required far-reaching changes, to establish four essential elements connecting patients and doctors: biobanks, databases, bioinformatic platforms and genomic platforms. The “transformation” of scientific research areas, such as genetics, bioinformatics and biostatistics, into clinical specialties has generated a new vision (...) of care. Molecular tumor boards are one response to these changes and are now providing better access to next-generation sequencing and new cancer treatments to patients with inoperable or metastatic cancers, and those for whom the usual treatment has failed. However, MTB face a crucial ethical challenge: maintaining and improving the trust of patients, clinicians, researchers and industry in academic medical centers supported by private or public funding rather than providing genetic data directly to private companies. We believe that, in this era of DM, appropriate modern digital communication networks will be required to maintain this trust and to improve the organization and effectiveness of the system. There is, therefore, a need to reconsider the form and content of informed consent documents at all academic medical centers and to introduce dynamic and electronic informed consent. (shrink)

Given a 4-tuple of Boolean variables (a, b, c, d), logical proportions are modeled by a pair of equivalences relating similarity indicators ( \({a \wedge b}\) and \({\overline{a} \wedge \overline{b}}\) ), or dissimilarity indicators ( \({a \wedge \overline{b}}\) and \({\overline{a} \wedge b}\) ) pertaining to the pair (a, b), to the ones associated with the pair (c, d). There are 120 semantically distinct logical proportions. One of them models the analogical proportion which corresponds to a statement of the form “a (...) is to b as c is to d”. The paper inventories the whole set of logical proportions by dividing it into five subfamilies according to what they express, and then identifies the proportions that satisfy noticeable properties such as full identity (the pair of equivalences defining the proportion hold as true for the 4-tuple (a, a, a, a)), symmetry (if the proportion holds for (a, b, c, d), it also holds for (c, d, a, b)), or code independency (if the proportion holds for (a, b, c, d), it also holds for their negations \({{(\overline{a},\overline{b}, \overline{c}, \overline{d})}}\) ). It appears that only four proportions (including analogical proportion) are homogeneous in the sense that they use only one type of indicator (either similarity or dissimilarity) in their definition. Due to their specific patterns, they have a particular cognitive appeal, and as such are studied in greater details. Finally, the paper provides a discussion of the other existing works on analogical proportions. (shrink)

The objective of this study is to analyze the measurability and interfirm comparability of sustainability performance through the qualitative content analysis of 12 sustainability reports of mining firms using the Global Reporting Initiative guidelines. The systematic comparison of information disclosed in 92 GRI indicators sheds light on the reasons underlying the impossibility of rigorously measuring and comparing the sustainability performance of firms from the same sector, which are supposed to be strictly following the same reporting guideline. These reasons include qualitative (...) aspects of sustainability, lack of compliance with GRI protocols, indicator contingency, ambiguous or incomplete information, data heterogeneity, and report opacity. The study makes it possible to return to the very notion of sustainability, its meaning, and flexible application by organizations. The results are discussed from three different theoretical perspectives, each of which proposes possible and complementary explanations of the main findings. (shrink)

Considers the problem of stylistic change in art, arguing that art is not reducible to external political, social, or economic determinants.

Volume 20, Issue 7, July 2020, Page W1-W1.

The Löwenheim-Hilbert-Bernays theorem states that, for an arithmetical first-order language L, if S is a satisfiable schema, then substitution of open sentences of L for the predicate letters of S...

In lieu of an abstract, here is a brief excerpt of the content:Notes and Discussions NOTE SUR G. SEBBA,"A 'NEw' DESCARTESEDITION?"* Puisque le titre du tr~s int~ressant article: "A 'New' Descartes Edition?" contient un point d'interrogation, donnons imm~diatement la r6ponse: non, il ne s'agit pas d'une 6dition vraiment "nouvelle." Le professeur Gregor Sebba a tr~s exactement expos6 les raisons qui justifieraient une "nouvelle ~dition": le projet de la Librairie Vrin pretend simplement ~tre une solution empirique et provisoire. Des professeurs et (...) des chercheurs ont actuellement besoin de l'6dition Adam et Tannery pour pr6parer des cours ou des theses ou des articles: on va leur procurer les onze 1 volumes sous un format plus commode, certains ~tant divis~s en deux tomes; avec le concours de Centre National de la Recherche Scientifique, nous esp6rons que le prix de vente de chaque tome ne sera pas trop 61ev6; enfin, si minutieuse que soit la r6vision, rien n'empdchera une publication rapide. IIne peut &re question de commentaires. Mais, par des cahiers suppl6mentaires ajout6s ~t chaque volume et particuli~rement importants pour les tomes de la Correspondance, le lecteur saura tout ce que l'6rudition contemporaine ajoute, depuis 1913, ~ notre connaissance des textes cartesiens. Bien entendu, on reprendra ce que L6on Roth a apport6 sur la correspondance de Descartes avec Huygens. M. Bernard Rochot fera entrer darts les appendices tousles 616merits actuellement connus de la future 6dition critique que souhaite M. Gregor Sebba. Quant,h cette 6dition critique, elle est une oeuvre de longue haleine. I1 conviendrait, en particulier, de reviser les notices qui pr6sentent chaque lettre, d'op6rer un s6rieux contr61e des dates propos6es, de reprendre l'6dition des textes du t. X comme le demande M. Gregor Sebba. Tousles historiens de Descartes souhaitent qu'un nouvel Adam et un nouveau Tannery se chargent d'un travail aussi utile. Mais ceux que la Librairie Vrin a consuh~s ont pens6 que, en attendant, une r6-6dition de l'"Adam et Tannery," mis "hjour, si l'on peut dire, ~3tait devenue indispensable. HENRI GOUHIER Paris, France 9 Journal o[ the tlistory o[ Philosophy, Vol. I, No. 2 (1963), pp. 231-236. xII n'est pas question de r6-6diter let. XII, c'est.h-dire la Fie de Descartes par Ch. Adam. [71]... (shrink)

Organoids, in general, have become an established theme in bioethics. However, brain organoids are almost unique due to the vital and symbolic nature of the organ they reproduce, albeit partially,...

On the nature of mathematical reasoning -- Mathematical magnitude and experience -- Non-Euclidian geometries -- Space and geometry -- Experience and geometry -- Classical mechanics -- Relative and absolute motion -- Energy and thermodynamics -- Hypotheses in physics -- Theories of modern physics -- Probability calculus -- Optics and electricity -- Electrodynamics -- The end of matter.

This review of Turner’s “Computational Artifacts” focuses on one of the key novelties of the book, namely the proposal to understand the nature of computer programs as a “trinity” of specification, symbolic program, and physical process, replacing the traditional dualist views of programs as functional/structural or as symbolic/physical. This trinitarian view is found to be robust and helpful to solve typical issues of dualist views. Drawing comparisons with Simon’s view of the artifact as an interface, the author suggests that this (...) trinitarian view may characterize not only computational artifacts but also artifacts in general. One ambiguity is however noticed on the denotation of what Turner actually calls the “physical process.”. (shrink)