Cortical stimulation has been used for brain mapping for over a century, and a standard assumption is that stimulation interferes with task execution due to local effects at the stimulation site. Stimulation can however produce afterdischarges which interfere with functional localization and can lead to unwanted seizures. We previously showed that cognitive effort can terminate these afterdischarges, when termination thus occurs, there are electrocorticography changes throughout the cortex, not just at sites with afterdischarges or sites thought functionally important for the (...) cognitive task used, and thresholds for afterdischarges and functional responses can change among stimulation trials. We here show that afterdischarge termination can occur prior to overt performance of the cognitive tasks used to terminate them. These findings, taken together, demonstrate that task-related brain changes are not limited to one or a group of functional regions or a specific network, and not limited to the time directly surrounding overt task execution. Discrete locations, networks and times importantly underpin clinical behaviors. However, brain activity that is diffuse in location and extended in time also affect task execution and can affect brain mapping. This may in part reflect fluctuating levels of attention, engagement, or motivation during testing. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Reconfiguring Modernity: Concepts of Nature in Japanese Political IdeologyWilliam R. LaFleurReconfiguring Modernity: Concepts of Nature in Japanese Political Ideology. By Julia Adeney Thomas. Berkeley, Los Angeles, and London: University of California Press, 2001. Pp. xvi + 225.Books written by persons who self-identify as intellectual historians usually lend themselves more easily to review in history journals than in those that focus on philosophy. Reconfiguring Modernity: Concepts of Nature in (...) Japanese Political Ideology, Julia Adeney Thomas' study of certain Meiji period thinkers is such a book. In 2002 it was awarded the John K. Fairbank Prize in history. Taking a cue to step into her topic from an early essay by Robert Bellah, one in which he had written that "the concern for nature has been a pervasive one in much of modern Japanese thought,"1 Thomas specifies her own search: "It is now time to recover the historical mutability of that concept, and to describe precisely its politics at particular moments in Japan's confrontation with modernity, both within the dominant ideology of the moment and with the alternatives to it" (pp. 30-31).Thomas is among those American students of Japan apparently trained to challenge the massive amounts of excavational scholarship and mile-high reputations of Japanese scholars of Japan. She picks arguments with some of the most highly respected Japanese minds of the twentieth century: the late Maruyama Masao, the late Ienaga Saburō, and Matsumoto Sannosuke.Although Thomas' criticisms tend to focus on those portions of the works of these prolific scholars that have been translated into English,2 some of her criticisms are certainly interesting and possibly valid. For instance, Maruyama, "who repeatedly excoriated Japan's reliance on the political authority of nature (shizen) " (p. 16), envisioned modernity, surely desirable, as involving a move "against Chu Hsi Confucianism"—that is, "an inevitable turning away from nature (shizen) to invention (sakui)" (p. 17). Nevertheless, Maruyama's hero, Ogyū Sorai (1666-1728), had understood "the narrative of modernity" but, tragically, stepped "back from invention at the critical moment, unable, it would seem, to embrace it as the culmination of the historical process" (p. 19).Thomas, rightly I think, indicates that most left and liberal thinkers in Europe and America in the early and mid-twentieth century were skeptical of an invocation of the "natural" in the making of political theory.3 However, she stakes a claim to being part of a different generation, one that rejects the old binary opposition between nature and culture—as well as the further assumption that Western political thinking had successfully disengaged itself from invoking the category of what is natural. Taking a cue from Stephen Toulmin's demonstration of how many of Europe's modernizers embraced and used, rather than rejected, concepts of nature,4 Thomas claims that, at least for us who now live "'on the far side of modernity,' nature can be seen [End Page 172] as multivalent rather than the antonym in a series of binary opposites." In practice this means that for us now, "nature can no longer appear synonymous with the anti-modern, the past, the oppressive, or the Orient" (p. 25).I ask that the reader highlight the sentences above. They constitute what in my view is the most important and by far the most interesting move made in Refiguring Modernity. I will return to them below. First, however, I will recapitulate the progression of the book's chapters. They move in the pattern of linear history. The first, discussed already and titled "The Trouble with Nature," introduces the problem. The second, "The Topographical Imagination of Tokugawa Politics," deals with thinkers of the Tokugawa (Edo) period (1600-1868). Theirs was an era during which, although Chinese claims to being both topographically and morally central had long been dutifully accepted in Japan, strong-thinking Japanese argued that China's frequent dynastic changes demonstrated that "centralness need not be possessed physically to be enacted morally" (p. 42). By outdoing contemporaneous Chinese in terms of being Confucian, Neo-Confucian, or whatever it was that had its origins in China, Japanese and in some sense Japan as a whole were imagined to be the "real China."5... (shrink)

One of the most important of Japan's movements in search of a national identity during the 17th-18th centuries was known as kokugaku (national studies). It was the first major movement through which the intrinsic values inherent in ancient Japanese life were rediscovered from studies of early Japanese texts. Motoori Norinaga (1730-1801) was its greatest leader.

The origins of Japan's medical ideas, which are deeply rooted in its religion, culture and history, are not widely understood in medical societies of other countries. We have taken up the task of summarising this tradition here so that some insight can be gained into the unique issues that characterise the practice of medicine in Japan. We borrow from the sayings of Tohkaku Wada, a medical philosopher of late eighteenth-century Japan, for a look at Japanese medical tradition. Wada's medical thought (...) was very much reflective of the Buddhism, Zen, and swordsmanship that informed eighteenth-century philosophy in Japan. His central concepts were “chu” and “sei”, that is, complete and selfless dedication to the patient and the practice of medicine. This paper explores Wada's thought, explaining it mainly from the standpoint of Japanese traditional culture. (shrink)

Experience of matter can be described in the context of time and space, whereas, some people say, experience of mind may be described according to time only. Accordingly, though time and space together are regarded as objective forms, one may have a propensity for treating time alone as a particular form of the subjective consciousness. For space is indeed referred to the self-evidence of being, while time is thought to belong rather to the self-evidence of our own consciousness. According to (...) my opinion, however, even the spatial description is indispensable for the state of “mind”. For instance, the contents of our consciousness can be described only in terms of the localized phases of their images. Contrary to Kant, who regarded time and space together as forms of the outer intuition (i.e. as conditions of sensation), and time alone as form of the inner sense, I have a firm intention to assert them both as two forms of objective being because it is the being itself that can be the ultimate object of any of our cognitive powers — sensation, understanding and reason. Time and space are not forms proper to a particular “being” such as conscious existence like ours; they are also, nay, above all, two objective forms of being in general that transcends all such limited existences. It follows that these forms themselves, once abstracted in our mind, must, first of all, be valid for material beings; after that, i.e. derivatively and analogically, they may also be valid for mind-beings. The main aim of this paper is “dialectically” to elucidate that fact on the subject of time in particular. (shrink)

In this paper, I discuss the problems of ``order in social situations'' using a computer simulation of iterated N -person prisoners' dilemma game. It has been claimed that, in the case of the 2 -person prisoners' dilemma, repetition of games and the reciprocal use of the ``tit-for-tat'' strategy promote the possibility of cooperation. However, in cases of N -person prisoners' dilemma where N is greater than 2, the logic does not work effectively. The most essential problem is so called ``sanctioning (...) problems''. In this paper, firstly, I discuss the ``sanctioning problems'' which were introduced by Axelrod and Keohane in 1986. Based on the model formalized by Axelrod, I propose a new model, in which I added a mechanism of players' payoff changes in the Axelrod's model. I call this mechanism norm-internalization and call our model `` norm-internalization game ''. Second, by using the model, I investigated the relationship between agents' norm-internalization (payoff-alternation) and the possibilities of cooperation. The results of computer simulation indicated that unequal distribution of cooperating norm and uniform distribution of sanctioning norm are more effective in establishing cooperation. I discuss the mathematical features and the implications of the results on social science. (shrink)

Reason and Value collects 15 new papers by leading contemporary philosophers on themes from the work of Joseph Raz. Raz has made major contributions in a wide range of areas, including jurisprudence, political philosophy, and the theory of practical reason; but all of his work displays a deep engagement with central themes in moral philosophy. The subtlety and power of Raz's reflections on ethical topics make his writings a fertile source for anyone working in this area. Especially significant are his (...) explorations of the connections between practical reason and the theory of value, which constitute a sustained and penetrating treatment of a set of issues at the very center of moral philosophy as it is practiced today. The contributors to the volume acknowledge the importance of Raz's contributions by engaging critically with his positions and offering independent perspectives on the topics that he has addressed. The volume aims both to honour Raz's accomplishments in the area of ethical theorizing, and to contribute to an enhanced appreciation of the significance of his work for the subject. (shrink)

Although we have learned much about the neuropsychological control of facial expressions of emotion, there is still much work to do. We suggest that future work integrate advances in our theoretical understanding of the roles of volition and consciousness in the elicitation of emotion and the production of facial expressions with advances in our understanding of its underlying neurophysiology. We first review the facial musculature and the neural paths thought to innervate it, as well as previous attempts at understanding the (...) neural control of facial expressions of emotion, focusing on the voluntary-involuntary dichotomy and studies of hemispheric specialization. In the second section, we discuss four major aspects of the psychology of facial expressions of emotion that have particular import to their neurophysiological substrates. We offer these as a starting point for a better integration of psychological and neurophysiological perspectives in considering the neuropsychological control of facial expressions of emotion. (shrink)

Human beings express affinity (Shinwa‐kan in Japanese language) in communicating transactive engagements among healthcare providers, patients and healthcare robots. The appearance of healthcare robots and their language capabilities often feature characteristic and appropriate compassionate dialogical functions in human–robot interactions. Elements of healthcare robot configurations comprising its physiognomy and communication properties are founded on the positivist philosophical perspective of being the summation of composite parts, thereby mimicking human persons. This article reviews Mori's theory of the Uncanny Valley and its consequent debates, (...) and examines "Uncanny" relations with generating healthcare robot conversational content with artificial affective communication (AAC) using natural language processing. With healthcare robots provoking influential physical composition and sensory expressions, the relations in human–healthcare robot transactive engagements are argued as supportive of the design and development in natural language processing. This implies that maintaining human–healthcare robot interaction and assessing the eeriness situations explained in the Uncanny Valley theory are crucial positions for healthcare robot functioning as a valuable commodity in health care. As such, physical features, language capabilities and mobility of healthcare robots establish the primacy of the AAC with natural language processing as integral to healthcare robot–human healthcare practice. (shrink)

Crew Pairing is one of the most important and difficult problems for airline companies. Nets to fuel costs, the crew costs constitute the largest cost of airlines, and the crew costs depend on the quality of the solution to the pairing problem. Conventional systems have been used to solve a daily model, which handles only regular flights with many simplifications, so a lot of corrections are needed to get a feasible solution and the quality of the solution is not so (...) high. A fully dated model, which handles regular flights and irregular flights simultaneously, is extremely hard and has not been solved directly hitherto. The number of irregular flights tend to increase in Europe and Japan, hence the resolution of the practical fully dated pairing system is desired. This paper presents a new approach which solves directly the fully dated crew pairing by Genetic Algorithms. GA is improved with stochastic processes to attack the fully dated model, and many heuristics are included in the decoding mecanism of the GA. For several hundred flights per day for fully dated 2 months scheduling period, the system found better or equivalent solutions to the human scheduler’s without any simplification from 5 to 20 times faster. (shrink)

To preserve postoperative brain function, it is important for neurosurgeons to fully understand the brain's structure, vasculature, and function. Intraoperative high-frequency electrical stimulation during awake craniotomy is the gold standard for mapping the function of the cortices and white matter; however, this method can only map the “focal” functions and cannot monitor large-scale cortical networks in real-time. Recently, an in vivo electrophysiological method using cortico-cortical evoked potentials induced by single-pulse electrical cortical stimulation has been developed in an extraoperative setting. By (...) using the CCEP connectivity pattern intraoperatively, mapping and real-time monitoring of the dorsal language pathway is available. This intraoperative CCEP method also allows for mapping of the frontal aslant tract, another language pathway, and detection of connectivity between the primary and supplementary motor areas in the frontal lobe network. Intraoperative CCEP mapping has also demonstrated connectivity between the frontal and temporal lobes, likely via the ventral language pathway. Establishing intraoperative electrophysiological monitoring is clinically useful for preserving brain function, even under general anesthesia. This CCEP technique demonstrates potential clinical applications for mapping and monitoring large-scale cortical networks. (shrink)

This study considers food commercials featuring the term otona, meaning ‘adult, mature person’. Although the term is not explicitly gendered, this study demonstrates that food advertising using otona becomes a conduit for the construction of gendered lifestyle formulations via consumption practices offering consumers entrance into a range of gendered adult life stage practices. Unlike the socially aspirational consumption practices described by Agha, the consumption of inexpensive otona-marked products, which cost the same as their non-otona-marked counterparts but are intended by commercial (...) producers to be viewed by prospective consumers as more mature, is linked to the process of entering adulthood. However, whereas male performance of otona masculinity is shown in the commercials to be based on psychological maturity and economic and social independence, female performance of otona femininity is determined by the commercial producers and the product manufacturers to be based on successful performance of external beauty, sexuality and support of male social sphere members. This article shows how otona becomes a catch-all for aspirational gendered performance, arguing that terms like otona are particularly suited for normative gendered performance presentations. (shrink)

The geographically inequitable distribution of physicians has long posed a serious social problem in Japan. The government tackled this problem by establishing and managing Jichi Medical University (JMU) and regional quotas (RQs) for medical schools. JMU/RQs recruit local students who hope to work as physicians in rural areas, educate them for 6 years without tuition (JMU) or with scholarship (RQs), and after graduation, assign them to their home prefectures for 9 years, including 4–6 years of rural service. JMU/RQs entrants now (...) occupy 11.6% of all medical school entrants. While JMU/RQs have been shown to be highly effective in securing physicians for rural areas, ethical issues related to these policies have been raised, such as whether the government truly needs to implement these policies using tax money, and whether it is acceptable to limit the personal freedoms of the physicians. In this paper, we discuss these issues from the perspectives of social justice, utilitarianism, luck egalitarianism, liberty, medical professionalism and consistency with national health insurance and the Japanese Constitution. We conclude that JMU/RQs are necessary and ethically valid policies, and also propose some institutional improvements to better secure the integrity and maturity of these systems. (shrink)

We posit a model of emotion and nonverbal behavior (NVB) that incorporates a perspective of consciousness. We leverage an understanding of the neural pathways innervating NVB to describe the complexity of its neural architecture and the links between those pathways and mental states. We suggest that all NVB are activated by both cortical and subcortical structures, allowing for unconscious, coordinated movements across multiple channels as well as conscious, less coordinated movements; that mental states are associated with both cortical and subcortical (...) structures; and thus that NVB will occur in multiple channels, both unconsciously and consciously, and differ across time. We discuss the implications of this model for future theory and research. (shrink)

According to Wierzbicka, one of the core values of Polish culture is sincerity and emotional frankness, in this study we tested this assumption analyzing display rules operating between friends. 100 respondents completed modified version of the Display Rule Assessment Inventory. Results show that Polish participants endorse more expression with close friends than with acquaintances and strangers. The obtained differences between those groups were quite large and similar to a pattern typical for collectivistic cultures. On the other hand, we reported high (...) level of overall expressivity, typical of individualism. Such a high expressivity was found for all studied emotions, but pride, which is consistent with previous research on self-presentational modesty in Polish culture. (shrink)

Researchers have been interested in what retrieval process is responsible for overgeneral autobiographical memories (OGM) in depression. Previous cross-sectional studies demonstrated that, for negatively valenced cues, directly retrieved OGM, rather than generatively retrieved OGM, are associated with depression. However, longitudinal evidence of this relationship is still lacking and needs to be tested. We conducted a re-analysis of the online computerised memory specificity training (c-MeST) data to examine whether directly retrieved OGM for negative cues prospectively predicts high levels of depression 1 (...) month later. Participants who met the criteria of current major depressive disorders (N = 116; n = 58 in the c-MeST group and n = 58 in the control group) recalled autobiographical memories for positive and negative cues and judged each retrieval process (i.e. direct or generative). The results supported our prediction, and directly retrieved OGM for negative cues predicted high levels of depressive symptoms 1 month later even after controlling for the group effect, baseline depressive symptoms, executive functioning and rumination. Exploratory analysis showed that direct retrieval of specific memories prospectively predicted low levels of depression. These results support the theory that elevated accessibility of negatively valenced general memory representations is a vulnerability factor for depressive symptoms. (shrink)

IntroductionPrevious transcranial magnetic stimulation studies have revealed that the activity of the primary motor cortex ipsilateral to an active hand plays an important role in motor control. The aim of this study was to investigate whether the ipsi-M1 excitability would be influenced by goal-directed movement and laterality during unilateral finger movements.MethodTen healthy right-handed subjects performed four finger tapping tasks with the index finger: simple tapping task, Real-word task, Pseudoword task, and Visually guided tapping task. In the Tap task, the subject (...) performed self-paced simple tapping on a touch screen. In the real-word task, the subject tapped letters displayed on the screen one by one to create a Real-word. Because the action had a specific purpose, this task was considered to be goal-directed as compared to the Tap task. In the Pseudoword task, the subject tapped the letters to create a pseudoword in the same manner as in the Real-word task; however, the word was less meaningful. In the VT task, the subject was required to touch a series of illuminated buttons. This task was considered to be less goal-directed than the Pseudoword task. The tasks were performed with the right and left hand, and a rest condition was added as control. Single- and paired-pulse TMS were applied to the ipsi-M1 to measure corticospinal excitability and short- and long-interval intracortical inhibition in the resting first dorsal interosseous muscle.ResultsWe found the smaller SICI in the ipsi-M1 during the VT task compared with the resting condition. Further, both SICI and LICI were smaller in the right than in the left M1, regardless of the task conditions.DiscussionWe found that SICI in the ipsi-M1 is smaller during visual illumination-guided finger movement than during the resting condition. Our finding provides basic data for designing a rehabilitation program that modulates the M1 ipsilateral to the moving limb, for example, for post-stroke patients with severe hemiparesis. (shrink)

A major issue facing many businesses today, both large and small, concerns intercultural adaptation, and more broadly, diversity. Many businesses struggle with their employees sent to different countries and cultures to adapt effectively in host cultures, as well as for their home culture employees to adapt effectively to changing environments brought on by visitors from other cultures and other sources of diversity. To address this issue, many tests and measures have been developed to identify the core psychological skills, competencies, and (...) aptitudes underlying intercultural adaptation. Elucidation of such skills and competencies would have multiple theoretical and practical ramifications. A recent review of this literature indicated that three tests – the Multicultural Personality Questionnaire, the Cultural Intelligence Scale, and the Intercultural Adjustment Potential Scale – had the best psychometric evidence for validity to date. No study, however, has examined the statistical overlap among these tests; which scales or combination of scales best predict adaptation; and most importantly, what are the possible, yet unassessed, constructs underlying them. The purpose of this study was to examine these three questions initially. Non-immigrant, non-sojourner convenience samples from four countries/language groups completed all three tests and a measure of life satisfaction as a proxy for adaptation. Scales from the three tests were moderately – highly intercorrelated and predicted adaptation. A combination of scales from the tests best predicted adaptation, better than scales from any one test. Analyses examining the latent structures underlying the combined tests suggested several psychological constructs new to the intercultural adaptation literature. We discuss the implications of these findings for theory and application in international business. (shrink)

BackgroundEmotional regulation is important for adolescents’ adaptive development. Preventive interventions for anxiety and depression are necessary for reducing the development of disorders later in life, and emotional regulation is a potentially relevant factor.ObjectiveWe investigated the effects of a mindfulness-based psychological education and prevention program [the Mindfulness and Awareness Program ] on the mental health of junior high school students in Japan.MethodsOur MAP primarily focused on mindfulness meditation to improve emotional regulation, thereby reducing depression and anxiety. The MAP comprised eight sessions (...) administered by a school counselor in a school setting. All participants were 12–13-year-old adolescents from nine classes in two Japanese schools. The program was provided to the intervention group, wherein students were educated on emotional expression, emotional cognition, and emotional regulation. The control group received regular school counseling services.ResultsCompared with the control group, the intervention group showed significant improvement in emotional regulation and a decrease in depression and generalized anxiety. The effect was greater at the follow-up assessment than at the immediate post-intervention assessment, and greater in female students.ConclusionOur mental health prevention program exhibited efficacy in reducing depression and anxiety and enhancing emotional regulation in early adolescence. Further, it appeared to be more effective for female adolescents. (shrink)

CALHM1 was recently demonstrated to be a voltage‐gated ATP‐permeable ion channel and to serve as a bona fide conduit for ATP release from sweet‐, umami‐, and bitter‐sensing type II taste cells. Calhm1 is expressed in taste buds exclusively in type II cells and its product has structural and functional similarities with connexins and pannexins, two families of channel protein candidates for ATP release by type II cells. Calhm1 knockout in mice leads to loss of perception of sweet, umami, and bitter (...) compounds and to impaired gustatory nerve responses to these tastants. These new studies validate the concept of ATP as the primary neurotransmitter from type II cells to gustatory neurons. Furthermore, they identify voltage‐gated ATP release through CALHM1 as an essential molecular mechanism of ATP release in taste buds. We discuss these new findings, as well as unresolved issues in peripheral taste signaling that we hope will stimulate future research. (shrink)

Although the neural bases of the brain associated with movement disorders in children with developmental coordination disorder are becoming clearer, the information is not sufficient because of the lack of extensive brain function research. Therefore, it is controversial about effective intervention methods focusing on brain function. One of the rehabilitation techniques for movement disorders involves intervention using motor imagery. MI is often used for movement disorders, but most studies involve adults and healthy children, and the MI method for children with (...) DCD has not been studied in detail. Therefore, a review was conducted to clarify the neuroscientific basis of the methodology of intervention using MI for children with DCD. The neuroimaging review included 20 magnetic resonance imaging studies, and the neurorehabilitation review included four MI intervention studies. In addition to previously reported neural bases, our results indicate decreased activity of the bilateral thalamus, decreased connectivity of the sensory-motor cortex and the left posterior middle temporal gyrus, bilateral posterior cingulate cortex, precuneus, cerebellum, and basal ganglia, loss of connectivity superiority in the abovementioned areas. Furthermore, reduction of gray matter volume in the right superior frontal gyrus and middle frontal gyrus, lower fractional anisotropy, and axial diffusivity in regions of white matter pathways were found in DCD. As a result of the review, children with DCD had less activation of the left brain, especially those with mirror neurons system and sensory integration functions. On the contrary, the area important for the visual space processing of the right brain was activated. Regarding of characteristic of the MI methods was that children observed a video related to motor skills before the intervention. Also, they performed visual-motor tasks before MI training sessions. Adding action observation during MI activates the MNS, and performing visual-motor tasks activates the basal ganglia. These methods may improve the deactivated brain regions of children with DCD and may be useful as conditioning before starting training. Furthermore, we propose a process for sharing the contents of MI with the therapist in language and determining exercise strategies. (shrink)