Based on Medicine as a human experience / David E. Reiser, David H. Rosen. c1984.

Cognitive neuroscience has inspired a number of methodological advances to extract the highest signal-to-noise ratio from neuroimaging data. Popular techniques used to summarize behavioral data include sum-scores and item response theory. While these techniques can be useful when applied appropriately, item dimensionality and the quality of information are often left unexplored allowing poor performing items to be included in an itemset. The purpose of this study is to highlight how the application of two-stage approaches introduces parameter bias, differential item functioning (...) can manifest in cognitive neuroscience data and how techniques such as the multiple indicator multiple cause model can identify and remove items with DIF and model these data with greater sensitivity for brain–behavior relationships. This was performed using a simulation and an empirical study. The simulation explores parameter bias across two separate techniques used to summarize behavioral data: sum-scores and IRT and formative relationships with those estimated from a MIMIC model. In an empirical study participants performed an emotional identification task while concurrent electroencephalogram data were acquired across 384 trials. Participants were asked to identify the emotion presented by a static face of a child across four categories: happy, neutral, discomfort, and distress. The primary outcomes of interest were P200 event-related potential amplitude and latency within each emotion category. Instances of DIF related to correct emotion identification were explored with respect to an individual’s neurophysiology; specifically an item’s difficulty and discrimination were explored with respect to an individual’s average P200 amplitude and latency using a MIMIC model. The MIMIC model’s sensitivity was then compared to popular two-stage approaches for cognitive performance summary scores, including sum-scores and an IRT model framework and then regressing these onto the ERP characteristics. Here sensitivity refers to the magnitude and significance of coefficients relating the brain to these behavioral outcomes. The first set of analyses displayed instances of DIF within all four emotions which were then removed from all further models. The next set of analyses compared the two-stage approaches with the MIMIC model. Only the MIMIC model identified any significant brain–behavior relationships. Taken together, these results indicate that item performance can be gleaned from subject-specific biomarkers, and that techniques such as the MIMIC model may be useful tools to derive complex item-level brain–behavior relationships. (shrink)

The classical utilitarian legacy of Jeremy Bentham, J. S. Mill, James Mill, and Henry Sidgwick has often been charged with both theoretical and practical complicity in the growth of British imperialism and the emerging racialist discourse of the nineteenth century. But there has been little scholarly work devoted to bringing together the conflicting interpretive perspectives on this legacy and its complex evolution with respect to orientalism and imperialism. This volume, with contributions by leading scholars in the field, represents the first (...) attempt to survey the full range of current scholarly controversy on how the classical utilitarians conceived of 'race' and the part it played in their ethical and political programs, particularly with respect to such issues as slavery and the governance of India. The book both advances our understanding of the history of utilitarianism and imperialism and promotes the scholarly debate, clarifying the major points at issue between those sympathetic to the utilitarian legacy and those critical of it. (shrink)

Modeled on the classic Tao Te Ching, this startling and revealing new interpretation of Carl Jung's life and psychology parallels Jung's natural world of the psyche and that of Taoist philosophy, exploring the integration of such opposites as shadow/persona, yin/yang, dark/light, and feminine/masculine. Photos & drawings.

The course of German Idealism, which lasted from Kant to Schelling, is one of the most important and influential periods in the history of philosophy. _The Routledge Handbook of German Idealism_ is a superb resource for all students and scholars of the movement. Its twelve specially commissioned thematic chapters, all written by experts in the area, cover the essential aspects of German idealism, including Knowledge, nature, freedom and morality, law, history, religion, art and the European legacy of German idealism. In (...) addition to providing essential background to the thought of the period’s most important philosophers, Kant, Hegel, Fichte and Schelling, it also covers philosophers such as Herder, Holderlin, and Schleiermacher. Clearly written, it is accessible to any student of philosophy as well as those in other disciplines with an interest in German idealism, nineteenth century philosophy and continental philosophy. (shrink)

The course of German Idealism, which lasted from Kant to Schelling, is one of the most important and influential periods in the history of philosophy. _The Routledge Handbook of German Idealism_ is a superb resource for all students and scholars of the movement. Its twelve specially commissioned thematic chapters, all written by experts in the area, cover the essential aspects of German idealism, including Knowledge, nature, freedom and morality, law, history, religion, art and the European legacy of German idealism. In (...) addition to providing essential background to the thought of the period’s most important philosophers, Kant, Hegel, Fichte and Schelling, it also covers philosophers such as Herder, Holderlin, and Schleiermacher. Clearly written, it is accessible to any student of philosophy as well as those in other disciplines with an interest in German idealism, nineteenth century philosophy and continental philosophy. (shrink)

Previous work demonstrates that music with more surprising chords tends to be perceived as more enjoyable than music with more conventional harmonic structures. In that work, harmonic surprise was computed based upon a static distribution of chords. This would assume that harmonic surprise is constant over time, and the effect of harmonic surprise on music preference is similarly static. In this study we assess that assumption and establish that the relationship between harmonic surprise and music preference is not constant as (...) time goes on. Analyses of harmonic surprise and preference from 1958 to 1991 showed increased harmonic surprise over time, and that this increase was significantly more pronounced in preferred songs. Separate analyses showed similar increases over the years from 2000 to 2019. As such, these findings provide evidence that the human perception of tonality is influenced by exposure. Baseline harmonic expectations that were developed through listening to the music of “yesterday” are violated in the music of “today,” leading to preference. Then, once the music of “today” provides the baseline expectations for the music of “tomorrow,” more pronounced violations—and with them, higher harmonic surprise values—become associated with preference formation. We call this phenomenon the “Inflationary-Surprise Hypothesis.” Support for this hypothesis could impact the understanding of how the perception of tonality, and other statistical regularities, are developed in the human brain. (shrink)

Background Bioethical debates about privacy, big data, and public health surveillance have not sufficiently engaged the perspectives of those being surveilled. The data justice framework suggests that big data applications have the potential to create disproportionate harm for socially marginalized groups. Using examples from our research on HIV surveillance for individuals incarcerated in jails, we analyze ethical issues in deploying big data in public health surveillance. -/- Methods We conducted qualitative, semi-structured interviews with 24 people living with HIV who had (...) been previously incarcerated in county jails about their perspectives on and experiences with HIV surveillance, as part of a larger study to characterize ethical considerations in leveraging big data techniques to enhance continuity of care for incarcerated people living with HIV. -/- Results Most participants expressed support for the state health department tracking HIV testing results and viral load data. Several viewed HIV surveillance as a violation of privacy, and several had actively avoided contact from state public health outreach workers. Participants were most likely to express reservations about surveillance when they viewed the state’s motives as self-interested. Perspectives highlight the mistrust that structurally vulnerable people may have in the state’s capacity to act as an agent of welfare. Findings suggest that adopting a nuanced, context-sensitive view on surveillance is essential. -/- Conclusions Establishing trustworthiness through interpersonal interactions with public health personnel is important to reversing historical legacies of harm to racial minorities and structurally vulnerable groups. Empowering stakeholders to participate in the design and implementation of data infrastructure and governance is critical for advancing a data justice agenda, and can offset privacy concerns. The next steps in advancing the data justice framework in public health surveillance will be to innovate ways to represent the voices of structurally vulnerable groups in the design and governance of big data initiatives. (shrink)

Web scraping involves using computer programs for automated extraction and organization of data from the Web for the purpose of further data analysis and use. It is frequently used by commercial companies, but also has become a valuable tool in epidemiological research and public health planning. In this paper, we explore ethical issues in a project that “scrapes” public websites of U.S. county jails as part of an effort to develop a comprehensive database to enhance HIV surveillance and improve continuity (...) of care for incarcerated populations. We argue that the well-known framework of Emanuel et al. provides only partial ethical guidance for the activities we describe, which lie at a complex intersection of public health research and public health practice. We suggest some ethical considerations from the ethics of public health practice to help fill gaps in this relatively unexplored area. (shrink)

Peter Abelard (1079–1142 ce) was the most wide‐ranging philosopher of the twelfth century. He quickly established himself as a leading teacher of logic in and near Paris shortly after 1100. After his affair with Heloise, and his subsequent castration, Abelard became a monk, but he returned to teaching in the Paris schools until 1140, when his work was condemned by a Church Council at Sens. His logical writings were based around discussion of the “Old Logic”: Porphyry's Isagoge, aristotle'S Categories and (...) On Interpretation and boethius'S textbook on topical inference. They comprise a freestanding Dialectica (“Logic”; probably c.1116), a set of commentaries (known as the Logica [Ingredientibus], c. 1119) and a later (c. 1125) commentary on the Isagoge (Logica Nostrorum Petititoni Sociorum or Glossulae). In a work Abelard called his Theologia, issued in three main versions (between 1120 and c.1134), he attempted a logical analysis of trinitarian relations and explored the philosophical problems surrounding God's claims to omnipotence and omniscience. The Collationes (“Debates,” also known as “Dialogue between a Christian, a Philosopher and a Jew”; probably c.1130) present a rational investigation into the nature of the highest good, in which the Christian and the Philosopher (who seems to be modeled on a philosopher of pagan antiquity) are remarkably in agreement. The unfinished Scito teipsum (“Know thyself,” also known as the “Ethics”; c.1138) analyses moral action. (shrink)

This paper discusses the Einstein-Podolsky-Rosen paradox from a new point of view. In section II, the arguments by which Einstein, Podolsky and Rosen reach their paradoxical conclusions are presented. They are found to rest on two critical assumptions: (a) that before a measurement is made on a system consisting of two non-interacting but correlated sub-systems, the state of the entire system is exactly represented by: ψ a (r̄ 1 ,r̄ 2 )=∑ η a η τ η (r̄ 1 (...) ,r̄ 2 )=∑ i,k α ik ψ i (r̄ 1 )σ k (r̄ 2 ) (b) that the exact measurement of an observable A in one of the sub-systems is possible. In section III it is shown that assumption (b) is incorrect. Thus we conclude, as did Bohr, that the results of Einstein, Podolsky and Rosen are not valid. The arguments of section III are quite distinct from Bohr's, and therefore in Section IV this work is related to that of Bohr. (shrink)

This article explores the relationship between utility and justice in the ancient Epicurean tradition, and as it developed in the seventeenth and eighteenth centuries following the revival of Epicureanism in the writings of Pierre Gassendi. It focuses on the significance of various allusions to a line from Horace, ‘utilitas, justi prope mater et aequi’, which appeared in writings of Hugo Grotius, David Hume, and Jeremy Bentham, and was used to give utility a prominence in modern hought that it had (...) not hitherto received. The article attempts to provide the context for Hume’s belief in the Enquiry concerning the Principles of Morals that the foundation of justice was utility and for Bentham placing utility at the foundation of his system. (shrink)

This paper explores the meaning of time from three points of view: (1) David Bohm's concepts of "vertical implicate order" and "holomovement"; (2) Alfred North Whitehead's idea of the "actual occasion"; and (3) the author's notion of "nondual duality." The author argues that Bohm and Whitehead alike implicitly divide time into dual and nondual aspects and that, in failing to adequately reconcile these, time, in effect, is denied. The alternative offered seeks to thoroughly integrate dual and nondual (holistic) modalities (...) in the understanding that time as becoming entails a dynamic interpenetration of its opposing aspects. Visual geometry and topology are employed to flesh out the "nondual duality" of temporal structure. (shrink)

This article explores the relationship between utility and justice in the ancient Epicurean tradition, and as it developed in the seventeenth and eighteenth centuries following the revival of Epicureanism in the writings of Pierre Gassendi. It focuses on the significance of various allusions to a line from Horace, 'utilitas, justi prope mater et aequi' , which appeared in writings of Hugo Grotius, David Hume, and Jeremy Bentham, and was used to give utility a prominence in modern thought that it (...) had not hitherto received. The article attempts to provide the context for Hume's belief in the Enquiry concerning the Principles of Morals that the foundation of justice was utility and for Bentham placing utility at the foundation of his system. (shrink)

This paper defends the idea that there might be vagueness or indeterminacy in the world itself---as opposed to merely in our representations of the world---against the charges of incoherence and unintelligibility. First we consider the idea that the world might contain vague *properties and relations*; we show that this idea is already implied by certain well-understood views concerning the semantics of vague predicates (most notably the fuzzy view). Next we consider the idea that the world might contain vague *objects*; we (...) argue that an object is indeterminate in a certain respect (colour, size, etc.) just in case it is a borderline case of a maximally specific colour (size, etc.) property. Finally we consider the idea that the *world as a whole* might be indeterminate; we argue that the world is indeterminate just in case it lacks a determinate division into determinate objects. (shrink)

This book confronts basic anomalies in the foundations of contemporary science and philosophy. It deals with paradoxes that call into question our conventional way of thinking about space, time, and the nature of human experience.

Viewed from a suitable distance, David Lewis's ontological scheme is simplicity itself. Absolutely everything that exists, according to Lewis, is either a spatiotemporal particular, or a set theoretic construction from such particulars, or a mereological aggregate of such items. Set theoretic constructionalism is not an incidental feature of Lewis's system. The master argument of On the Plurality of Worlds is that a pluriverse composed of infinitely many concrete universes constitutes a “paradise for philosophers. Given his other views, his account (...) of classes has profound implications for general metaphysics, implying as it does an account of the nature of properties and instantiation, propositions and propositional truth, the nature of events, and so on. But Lewis does not consider those implications. The aim of this chapter is to close the circle by bringing Lewis's mature account of sets into contact with his larger ontological scheme. (shrink)

The Brock-Rosen problem has been one of the most thoroughly discussed objections to the modal fictionalism bruited in Gideon Rosen’s ‘Modal Fictionalism’. But there is a more fundamental problem with modal fictionalism, at least as it is normally explained: the position does not resolve the tension that motivated it. I argue that if we pay attention to a neglected aspect of modal fictionalism, we will see how to resolve this tension—and we will also find a persuasive reply to (...) the Brock-Rosen objection. Finally, I discuss an alternative reading of Rosen, and argue that this position is also able to fend off the Brock-Rosen objection. (shrink)

The tendency to see English utilitarianism as a fundamentally different enterprise from that of the so-called Scottish Enlightenment is mistaken. One must read Hume backwards, which, despite Hume’s own advice, is rarely done by Hume scholars. In doing so, one more fully appreciates the importance of utility to Hume, and Bentham’s subsequent employment of Hume’s ideas.

Platonism in the philosophy of mathematics is the doctrine that there are mathematical objects such as numbers. John Burgess and Gideon Rosen have argued that that there is no good epistemological argument against platonism. They propose a dilemma, claiming that epistemological arguments against platonism either rely on a dubious epistemology, or resemble a dubious sceptical argument concerning perceptual knowledge. Against Burgess and Rosen, I show that an epistemological anti- platonist argument proposed by Hartry Field avoids both horns of (...) their dilemma. (shrink)

Counterpart theory affords an especially flexible form of essentialism. Gideon Rosen and the author suggested that by endowing the entire world with peculiar essences, they could likewise provide truth makers for negative existential propositions. Thus they avoid the need for states of affairs or non‐transferable tropes as truth makers. States of affairs are somehow constructed from particular things and the properties they instantiate. A legitimate counterpart relation can exist which validates only one direction of set‐theoretical essentialism, but under which (...) any counterpart of a state of affairs must be a state of affairs. States of affairs or tropes are not needed for purposes of truth making. But also, if we help ourselves to the flexibility of counterpart theory, the principal difficulties that stand in the way of using states of affairs or tropes as truth makers vanish. (shrink)

David Bohm, Emeritus Professor of Theoretical Physics at Birkbeck College of the University of London and Fellow of the Royal Society, died of a heart attack on October 29, 1992 at the age of 74. Professor Bohm had been one of the world’s leading authorities on quantum theory and its interpretation for more than four decades. His contributions have been critical to all aspects of the field. He also made seminal contributions to plasma physics. His name appears prominently in (...) the modern physics literature, through the Aharonov- Bohm effect , the Bohm-EPR experiment , the Bohm-Pines collective description of particle interactions (random phase approximation), Bohm diffusion and the Bohm causal interpretation of quantum mechanics, also sometimes called the de Broglie-Bohm pilot wave theory. David Bohm was born in Wilkes-Barre, Pennsylvania on December 20, 1917. A student of J. Robert Oppenheimer, Bohm received his Ph.D. from the University of California at Berkeley in 1943. In 1950 he completed the first of his six books, Quantum Theory, which became the definitive exposition of the orthodox (Copenhagen) interpretation of quantum mechanics. Here Bohm presented his reformulation of the paradox of Einstein, Podolsky, and Rosen. It is this Bohm version of EPR which has provided the basis for the enormous expansion of research on the foundations of quantum theory, focusing on nonlocality and the possible incompleteness of the quantum description (the question of “hidden variables”), which has occurred during the past several decades. (shrink)

My theme is thought experiment in natural science, and its relation to real experiment. I shall defend the thesis that thought experiments that do not lead to theorizing and to a real experiment are generally of much less value that those that do so. To illustrate this thesis I refer to three examples, from three very different periods, and with three very different kinds of status. The first is the classic thought experiment in which Galileo imagined that he had, by (...) pure thought, demolished Aristoteles' dogma that heavier bodies fall more quickly than light ones. I will show that he was mistaken. The second is the Einstein-Podolsky-Rosen paper purporting to show that quantum mechanics must be incomplete in its domain of application. This thought experiment is a very good one, not because its conclusions are correct, but precisely because it was fruitful, leading to theory and, above all, to a real experiment. Finally I discuss the modern string theory of everything, which, while it is regarded as a physical theory by its instigators, shares some properties of the least successful sort of thought experiment. (shrink)

THE PAPER IS AN ATTEMPT TO ANSWER STANLEY ROSEN'S CHARGE\nTHAT MARX'S VIEW OF MAN IS EITHER NIHILISTIC OR INCOHERENT.\nIT IS ALLEGED THAT MARX'S NOTION THAT MAN MAKES HIMSELF\nLEADS TO THE NIHILISTIC CONCLUSION THAT EVERYTHING IS\nPERMISSIBLE. THUS, MARX'S CONCEPT OF HUMAN ALIENATION IS\nEMPTY BECAUSE HE CANNOT MAKE GOOD ON THE NORMATIVE CONCEPT\nOF UNALIENATED EXISTENCE. I ATTEMPT TO EXTRICATE MARX FROM\nROSEN'S DILEMMA BY SHOWING THAT MARX'S NOTION OF HUMAN\nSELF-CREATION IS NOT ONLY CONSISTENT WITH BUT REQUIRES THE\nAFFIRMATION OF A SOCIALIST FRAMEWORK. MARX'S (...) CONCEPT OF\nUNIQUE HUMAN NEEDS TURNS OUT TO BE CRUCIAL. (shrink)

Many philosophers of mathematics are attracted by nominalism – the doctrine that there are no sets, numbers, functions, or other mathematical objects. John Burgess and Gideon Rosen have put forward an intriguing argument against nominalism, based on the thought that philosophy cannot overrule internal mathematical and scientific standards of acceptability. I argue that Burgess and Rosen’s argument fails because it relies on a mistaken view of what the standards of mathematics require.

Benthamite utilitarianism was influential in Britain during the first half of the nineteenth century. Bentham and his followers took a special interest in the British colonies. As a result, key Australian institutions were strongly influenced by Bentham’s ideas, including in relation to democracy, law, and punishment. Benthamite radicals in London, and their associates in the colonies, had a profound influence on the development of the colonies through their activities in parliament, the law, and as theorists and activists. This paper draws (...) attention to some of the areas of influence of Bentham’s ideas in Australia, and reaches towards an understanding of why Australia has been described as a Benthamite society. (shrink)