La mission de forages menée en août 2015 aux alentours du site de Kirrha constitue le deuxième volet de la mission menée en octobre 2013 et devait permettre de répondre à différentes problématiques environnementales en lien avec le site archéologique de Kirrha, à savoir : Quelles ont été les grandes étapes d’édification de la plaine à l’échelle des 15 000 dernières années? Où et quand se sont installés les premiers occupants du site de Kirrha? Le site était‑il littoral? Était‑il situé (...) à pr... (shrink)

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain (...) in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

Después de unas reflexiones generales sobre lo que representa la experiencia griega de la pasión se consideran las posiciones de Platón y Aristóteles para luego subrayar en forma de contrapunto, la originalidad de la sicología estoica que, al no considerar la presencia de una irracionalidad inherente al alma humana, define la pasión como resultante de un error de juicio. Estas enfermedades del alma que, en una perspectiva estoica, son las pasiones revelan una incomprensión y un desacuerdo del hombre con su (...) entorno incapaz de vivir el presente. El discurso físico, propedéutico de la ética, es revelador de la conducta virtuosa librada de las pasiones. (shrink)

Developing countries face numerous barriers to conducting effective and efficient ethics reviews of international collaborative research. In addition to potentially overlooking important scientific and ethical considerations, inadequate or insufficiently trained ethics committees may insist on unwarranted changes to protocols that can impair a study's scientific or ethical validity. Moreover, poorly functioning review systems can impose substantial delays on the commencement of research, which needlessly undermine the development of new interventions for urgent medical needs. In response to these concerns, the Drugs (...) for Neglected Diseases Initiative, an independent nonprofit organization founded by a coalition of public sector and international organizations, developed a mechanism to facilitate more effective and efficient host country ethics review for a study of the use of fexinidazole for the treatment of late stage African Trypanosomiasis. The project involved the implementation of a novel ‘pre-review’ process of ethical oversight, conducted by an ad hoc committee of ethics committee representatives from African and European countries, in collaboration with internationally recognized scientific experts. This article examines the process and outcomes of this collaborative process. (shrink)

Conformément au protocole défini avec les autorités chypriotes, une opération d’étude et de fouille de la zone du bassin naturel, à l’emplacement supposé du port interne d’Amathonte, a débuté en 2014. Une première campagne de fouilles s’est tenue du 15 septembre au 10 octobre 2014. Elle fut précédée d’une enquête géomorphologique au printemps de la même année. La seconde fouille a eu lieu du 31 août au 25 septembre 2015. Des campagnes intermédiaires d’étude du matériel, essentiellement sur le...

L’étude des troubles de la voix et de la parole est sortie du cadre de la recherche clinique. Par l’observation des dysfonctionnements, les chercheurs non cliniciens confrontent les résultats de leur recherche établis sur des corpus de parole « normale » à des situations de dysfonctionnement. Le défi est immense car le cadre « pathologique » induit une variation considérable dans ses manifestations de surface. Toute généralisation à une population clinique particulière nécessite l’observation d’un grand nombre de patients du fait (...) de la très forte variation interindividuelle. Il est donc important de capitaliser et mutualiser les enregistrements existants. Or pour être utilisables, ces enregistrements doivent répondre à de fortes exigences. Le maillon faible reste la normalisation et la structuration des données sur les locuteurs et leurs productions langagières. Concrètement, si les données sonores sont souvent accessibles, elles ne présentent au final aucun intérêt si les liens entre les enregistrements et les caractéristiques cliniques du locuteur sont rompus ou erronés. L’objectif de ce travail est de présenter différentes actions de terrain et de proposer des recommandations pour la structuration des données sonores, physiologiques et cliniques dans le cas de corpus de parole issue de patients atteints de troubles de la voix et de la parole. (shrink)

Under the provisional title “Towards a Leibnizian History of Philosophy,” edited by Graeme Hunter, a number of Leibniz scholars will look at different aspects of the history of philosophy Leibniz would have written, had he written one. Contributors are Antoine Côté, Graeme Hunter, Yuen-Ting Lai, Michael Latzer, Tom Lennon, Robert McRae.

This article reports on a historical investigation carried out on the conical object MIN000-3519 preserved in the mineralogy collections of the Muséum National d'Histoire Naturelle at Paris (France). The mineralogist René-Just Haüy (1743-1822) included this object, cut in a single pyrite (FeS2) crystal, in his working collection with the references ‘Sulphured iron, mirror of the Incas, of Peru, M. de Jussieu’. All of the research lines followed lead the author to Joseph de Jussieu (1704-1779) and his shipments of botanical specimens (...) and various other samples from South America. As a member of the Godin-La Condamine-Bouguer geodesic expedition on the equator (1735-1743), he returned to France only after 36 years (1771), ill, exhausted and dispossessed of the scientific product of his Andean collections. This pyrite mirror is important because, in addition to appearing to be the only archaeological object that can be linked to Joseph's peregrinations in America, it resembles other specimens found at sites of the Cañaris culture (500-1500 AD) in Ecuador. Preserved within the de Jussieu family, this object would presumably have been given to Haüy by Joseph's heirs, his nephews Antoine-Laurent (1748-1836) or Laurent-Pierre (1792-1866), with whom he had close ties. (shrink)

There is a sort of natural closeness between Sartre and violence. Many have claimed that Sartre was fascinated by violence. Authors as diverse as Michel-Antoine Burnier and Mohamed Harbi have criticised the violence in Sartre, and even Bernard-Henri Lévy sees in Sartre's preface to Fanon's Les Damnés de la Terre a 'Sartre possédé'. Unlike these authors, we claim that Sartre was in no way fascinated by violence. In his eyes, violence was an historical fact that was characteristic of his (...) time and which he, personally, discovered at an early age. What is more, Sartre's violence is situational. If he discovered the world in books, it was also in books that he discovered violence. Books and history were the melting pots of a violence that haunts Sartre's work. The historical situations in which he found himself explain the omnipresence of violence in his work. (shrink)

Summary At the beginning of the 1730s René Antoine Ferchault de Réaumur published two long memoirs on a new type of thermometer equipped with a specially calibrated scale — known ever since as the Réaumur scale. It became one of the most common ‘standardized’ thermometers in Europe until the late nineteenth century. What made this thermometer so successful? What was it specifically? I will first argue that the real Réaumur thermometer as an instrument was a fiction, a ghost — (...) an idealized instrument. On paper, it was theoretically flawless. In reality, the standardized Réaumur thermometer was most likely never achieved. This article shows that its success was essentially due to a recontextualisation from theoretical natural philosophy — Réaumur's principle of uniformity — to: 1) the context of artisanal knowledge and practices and 2) the context of making and reporting in the Mémoires de l'Académie royale des sciences actual measurements done in the field (in Paris at the Observatory, in Provincial France, in the Colonies, and in the rest of Europe). Réaumur's thermometer was essentially a theoretical method to which was associated a particular scale. It was the instrument's reification for market consumption and fieldwork that gave this specific type of thermometer materiality and authority. Although most Réaumur thermometers ever made were strikingly different from one another, over time the thermomètre de Réaumur designation became a brand, a seal of approval born from customary artisanal practices and cultural habitudes. (shrink)

The focus of this paper is the intertextual relationship between the work of François Truffaut and that of Honoré de Balzac. It explores Balzac's influence on the shaping of Truffaut's voice and argues that Balzac's Human Comedy served Truffaut as a model for some of his cinematic innovations. This applies to Truffaut's total oeuvre, but particularly to his series of autobiographical films, “The Adventures of Antoine Doinel”: The 400 Blows (Les Quatre Cents Coups, 1959), Antoine and Colette, (...) Love at Twenty (Antoine et Colette, L'Amour à Vingt Ans, 1962), Stolen Kisses (Baisers Volés, 1968), Bed and Board (Domicile Conjugal, 1970), Love on the Run (L'Amour en Fuite, 1979). In examining Truffaut's “rewriting” of Balzac, I adopt—and adapt—the intertextual approach of Harold Bloom's theory of the “anxiety of influence.” My paper applies Bloom's concept of misreading to an examination of the relationship between Truffaut's autobiographical films, and Balzac's Human Comedy, both thematically and structurally. (shrink)

This essay focuses on an unknown Latin translation of Georg Ernst Stahl's treatise on the nature of sulfur (Zufällige Gedancken und Nützliche Bedencken über den Streit von dem so genannten Sulfure). The original edition, published in 1718, laid the foundation for the phlogiston theory, which dominated European chemistry until the early 1770s. However, the dissemination of the treatise on sulfur outside the German states remained limited. Its Latin translation proposes a different scenario as it was owned by three prominent French (...) chemists: Étienne-François Geoffroy, Jean Hellot and Antoine-Laurent Lavoisier. Geoffroy's early interest in Stahl's chemistry has been evidenced and it is suggested that the acquisition of the manuscript might be linked to his connection with Stahl through Caspar Neumann, a chemist from Berlin. When he entered in the possession of the manuscript Jean Hellot wrote a long excerpt of Stahl’s work. Lavoisier acquired the manuscript in 1766, and his critical reading of Stahl's work significantly influenced his own effort to outline a new theory of combustion. This manuscript represents a significant historical connection between Stahl’s phlogiston theory and Lavoisier's revolutionary ideas. (shrink)

Luca M. Possati, Jean Grondin, Paul Ricoeur ; Aurore Dumont, François Dosse et Catherine Goldenstein, Paul Ricoeur: penser la mémoire ; Paul-Gabriel Sandu, Gert-Jan van der Heiden, The Truth of Language. Heidegger, Ricoeur and Derrida on Disclosure and Displacement ; Paul Marinescu, Marc-Antoine Vallée, Gadamer et Ricoeur. La conception herméneutiquedu langage ; Witold Płotka, Saulius Geniusas, Th e Origins of the Horizon in Husserl’s Phenomenology ; Delia Popa, Annabelle Dufourcq, La dimension imaginaire du réel dans la philosophie de (...) Husserl ; Maria GyemantDenis Seron, Ce que voir veut dire. Essai sur la perception ; Christian Ferencz-Flatz, Hans Friesen, Christian Lotz, Jakob Meier, Markus Wolf, Ding und Verdinglichung. Technik- und Sozialphilosophie nach Heidegger und der Kritischen Th eorie ; Bogdan MincăLarisa Cercel, John Stanley, Unterwegs zu einer hermeneutischen Übersetzungswissenschaft. Radegundis Stolze zu ihrem 60. Geburtstag ; Denisa Butnaru Johann Michel, Sociologie du soi. Essai d’herméneutique appliquée ; Ovidiu Stanciu, Jan Patočka, Aristote, ses devanciers, ses successeurs. Trad. fr. Erika Abrams ; Mădălina Diaconu, Emmanuel Alloa, Das durchscheinende Bild. Konturen einer medialen, Phänomenologie. (shrink)

This paper examines the self-measurement and self-tracking practices of a turn-of-the-nineteenth-century Genevese pastor and pedagogical innovator, François-Marc-Louis Naville, who extensively used Benjamin Franklin’s tools of moral calculation and a lesser known tool, Marc-Antoine Jullien’s moral thermometer, to set a direction to his life and to monitor and improve his moral character. My contribution sheds light on how technologies of quantification molded notions of personal responsibility and character within an emerging utilitarian context. I situate Naville’s use of these tools (...) within his work as a pastor in a parish of the Republic of Geneva and within the Genevese and Swiss pedagogical reform movement of the early nineteenth century. I provide a detailed examination of how Naville used and adapted Franklin’s and Jullien’s tools of moral accounting for his own moral and religious purposes. Time, God’s most precious gift to man, served Naville as the ultimate measure of his moral worth. (shrink)

Nietzsche once proclaimed himself the 'Buddha of Europe', and throughout his life Buddhism held enormous interest for him. While he followed Buddhist thinking in demolishing what he regarded as the two-headed delusion of Being and Self, he saw himself as advocating a response to the ensuing nihilist crisis that was diametrically opposed to that of his Indian counterpart. In this book Antoine Panaïoti explores the deep and complex relations between Nietzsche's views and Buddhist philosophy. He discusses the psychological models (...) and theories which underlie their supposedly opposing ethics of 'great health' and explodes the apparent dichotomy between Nietzsche's Dionysian life-affirmation and Buddhist life-negation, arguing for a novel, hybrid response to the challenge of formulating a tenable post-nihilist ethics. His book will interest students and scholars of Nietzsche's philosophy, Buddhist thought and the metaphysical, existential and ethical issues that emerge with the demise of theism. (shrink)

To fulfill their crucial duty of relieving suffering in their patients, physicians may have to administer palliative sedation when they implement treatment-limitation decisions such as the withdrawal of life-supporting interventions in patients with poor prognosis chronic severe brain injury. The issue of palliative sedation deserves particular attention in adults with serious brain injuries and in neonates with severe and irreversible brain lesions, who are unable to express pain or to state their wishes. In France, treatment limitation decisions for these patients (...) are left to the physicians. Treatment-limitation decisions are made collegially, based on the presence of irreversible brain lesions responsible for chronic severe disorders of consciousness. Before these decisions are implemented, they are communicated to the relatives. Because the presence and severity of pain cannot be assessed in these patients, palliative analgesia and/or sedation should be administered. However, palliative sedation is a complex strategy that requires safeguards to prevent a drift toward hastening death or performing covert euthanasia. In addition to the law on patients' rights at the end of life passed in France on April 22, 2005, a recent revision of Article 37 of the French code of medical ethics both acknowledges that treatment-limitation decisions and palliative sedation may be required in patients with severe brain injuries and provides legal and ethical safeguards against a shift towards euthanasia. This legislation may hold value as a model for other countries where euthanasia is illegal and for countries such as Belgium and Netherlands where euthanasia is legal but not allowed in patients incapable of asking for euthanasia but in whom a treatment limitation decision has been made. (shrink)

Deux décennies après les premières vagues de démocratisation en Afrique, le temps n'est-il pas venu d'instruire le " procès " de la démocratie ?

The epistemology of models has to face a conundrum: models are often described as highly idealised, and yet they are considered to be vehicles for scientific explanations. Truth-oriented—veritist—conceptions of explanation seem thereby undermined by this contradiction. In this article, I will show how this apparent paradox can be avoided by appealing to the notion of fiction. If fictionalism is often thought to lead to various flavours of instrumentalism, thereby weakening the veritist hopes, the fiction view of models offers a framework (...) much richer than it seems at first sight. To do so, I will call upon the concepts of modality, counterfactual structure and credible worlds. In the end, veritism of explanation and fiction can indeed go hand in hand, but the scope of explanations we can hope to draw from models must be more precisely delineated. (shrink)

In the present article I attribute to the common topic in the Rhetoric a two-fold suggestive function and a guarantee function. These three functions are possible because this type of topic, while often quite abstract, nevertheless contains thought-steering, substantial terms, and formulates a generally empirical or normative endoxon. Assuming that according to Aristotle an enthymeme has at least two premises, it would appear that a common topic is the abstract principle behind the often implicit major premise. This means that the (...) topic may be regarded as the – generalizing – if-then statement in a modern argumentation scheme. Therefore it should be possible to see the enthymemes of Rhetoric 2.23 as a combination of a logical argument form (which can usually be reconstructed as modus ponens) and an argumentation scheme – even though we may not attribute this idea to Aristotle himself. (shrink)

The paper presents a research programme for the neuroscience of consciousness called 'neurophenomenology' and illustrates it with a recent pilot study . At a theoretical level, neurophenomenology pursues an embodied and large-scale dynamical approach to the neurophysiology of consciousness . At a methodological level, the neurophenomenological strategy is to make rigorous and extensive use of first-person data about subjective experience as a heuristic to describe and quantify the large-scale neurodynamics of consciousness . The paper focuses on neurophenomenology in relation to (...) three challenging methodological issues about incorporating first-person data into cognitive neuroscience: first-person reports can be biased or inaccurate; the process of generating first-person reports about an experience can modify that experience; and there is an 'explanatory gap' in our understanding of how to relate first-person, phenomenological data to third-person, biobehavioural data. (shrink)

Il est donc devenu banal de dire que Marx n'a pas laissé de théorie achevée de l'Etat et de la politique. Nombreux sont cependant les textes dans lesquels Marx apporte des éléments décisifs à l'analyse de la dimension politique d'une conjoncture et sur l'évolution des formes étatiques du XIXe siècle. Mais on ne trouve pas chez lui une théorie de l'Etat moderne équivalente à son analyse des rapports de production dans le " capital ". Cela laisse en suspens des problèmes (...) d'importance. Ainsi, comment concevoir le lien entre le rapport salarial, la forme juridique et la représentation politique? Il en est de même pour les phénomènes bureaucratiques. Cela lègue aussi un point aveugle sur une question cruciale : que faut-il entendre par dépérissement de l'Etat? Antoine Artous aborde ces problèmes sans chercher à les esquiver, au travers d'un effort pour "faire parler les textes de Marx". Il ne s'agit pas de restituer une pensée mal comprise ou trahie. Il s'agit d'une lecture critique qui n'hésite pas à relever les lacunes, à mettre Marx à l'épreuve de sa postérité. Un dialogue ainsi s'organise avec des auteurs tels que Max Weber, Nicos Poulantzas ou Ernst Bloch. Pour Antoine Artous, l'œuvre de Marx ne peut sortir indemne de l'inscription historique du marxisme dans ce siècle. Croire le contraire serait illusoire. Elle apparaît néanmoins incontournable pour qui veut penser la formidable rupture dans l'histoire des sociétés que représente l'avènement de l'Etat moderne. Incontournable aussi pour qui veut réfléchir sur les perspectives politiques des luttes d'émancipation. (shrink)

The Rhetoric to Alexander (about 340 B.C.) contains a list of proofs (pisteis) and other types of argumentation which may be seen as the oldest surviving typology of argumentation schemes (avant la lettre). In the present article this typology is derived and compared with modern proposals. The conclusion is that the oldest typology is surprisingly similar to the most recent classifications.

The lasting effects of the debate over canon-formation during the 1980s affected the whole field of Humanities, which became increasingly engaged in interrogating the origin and function of the Western canon. In philosophy, a great deal of criticism was, as a result, directed at the traditional narrative of seventeenth-and eighteenth-century philosophies—a critique informed by postcolonialism as well as feminist historiography. D. F. Norton, L. Loeb and many others1 attempted to demonstrate the weaknesses of the tripartite division between rationalism, empiricism and (...) critical philosophy.2 As time went on, symptoms of dissatisfaction with what has... (shrink)

Abstract In initial teacher training, the micro-teaching activities and retroaction have for goals to develop reflexive practitioners and competent professionals with a high professional identity. The double analyze of the teacher’s action – observation of teacher gestures and analysis of retroaction - requires two complementary methods to make the links between interactive and postactive phase. In this article, the authors describe the different training activities, and explain the research approach with an illustration of a concrete case. -/- En formation initiale (...) des enseignants, les activités de micro-enseignement et de rétroaction vidéo ont pour objectif de former des praticiens réflexifs et des professionnels compétents dotés d’une identité forte. La double lecture de l’action, via l’observation des gestes professionnels et l’analyse des traces de réflexivité survenues contenu lors des entretiens de rétroactions, nécessite de mettre en place deux méthodes complémentaires, ceci afin de faire les liens entre phase interactive et phase postactive. Dans cet article, après avoir détaillé le dispositif de formation, les auteurs exposent leurs démarches en les illustrant par le cas concret d’une future enseignante. (shrink)

Spiritualism designates a philosophy that lays claim to the separation of mind and body and the ontological and epistemological primacy of the former. In France, it is associated with the names of Victor Cousin and René Descartes, or more precisely with what Cousin made of Descartes as the founding father of a brittle rational psychology, closed off from the positive sciences, and as a critic in respect to the empiricist legacy of the idéologues. Moreover, by considering merely the end result, (...) severed from its polemical genesis, we are prevented from understanding how the category of experience constituted a crucial question for spiritualism itself. Through returning to the origin of these discussions in the 1826 preface to Cousin’s Fragments philosophiques, this essay pursues a threefold path: to show that the public birth of Cousinian spiritualism coincides with the affirmation of applying the experimental method, issuing from Bacon, to the study of facts of consciousness; that Cousin’s later evolution follows a process of radicalization—that is, in this context, of ontologization and of reduction; and that by recovering this genesis, we can distinguish many forms of spiritualisms committed to the experimental method, both in alliance with the early Cousin and against the later Cousin. In this way, we can rediscover the interwoven philosophical links, lost in the process of institutionalization, between metaphysical demands and empiricist concerns, or between “French” philosophy and the legacy of Condillac. (shrink)

Laboratoire de Neurosciences Cognitives et Imagerie Ce´re´brale (LENA), Hoˆpital de La Salpeˆtrie`re, Centre National de la Recherche Scientifique (CNRS).

Examines the theories of translation by German romantics in the early 19th century, from Novalis, Friedrich Schlegel, and A.W. Schlegel to Schleiermacher, and compares them briefly to the contemporary, but contrasting, theories by Herder, ...

C'est une vieille évidence qu'il n'est rien sujet à plus de continuelle agitation que les lois. Et en effet, l'ordre juridique est toujours instable. Il traduit un point d'équilibre momentané, qui n'était pas le seul possible, ni le seul prévisible. Le meilleur des Codes n'a jamais pu le fixer. Son contenu évolue sans cesse. Car, à l'image de la vie, le champ du droit est un espace ouvert, où s'affrontent un chaos de forces en perpétuel mouvement. Ni Providence, ni Progrès (...) n'y apparaissent avec certitude, l'esprit souffle apparemment où il veut et nul ne sait où il va. La preuve en est que la meilleure des règles en un temps donné finit toujours par avoir des effets pervers et qu'il est peu de lois vicieuses qui n'aient parfois d'heureux effets. Dans ces conditions, il ne faut pas attendre de l'enseignement du droit qu'il fournisse un catalogue de recettes pratiques, stables et sûres. Son seul but devrait être d'apprendre à poser les bonnes questions, qui sont presque toujours les mêmes, pour parvenir un jour à trouver de bonnes réponses, toujours provisoires. Or, aucune démarche n'est plus propice à la réalisation d'un tel but que la méthode historique. Elle révèle qu'il n'y a jamais de solution bonne et durable et que chaque civilisation, chaque génération doit trouver elle même ses propres réponses, avec une étroite marge de manœuvre. Pour trouver sa voie, explique l'auteur, ni la science, ni la philosophie ne livrent de clé. Si l'une peut l'éclairer et l'autre le guider, le droit n'est ni assimilable à une science, ni réductible à une philosophie. C'est un art subtil, qui nécessite de se plier à une discipline spécifique, mais dont la parfaite maîtrise dépasse celle des règles techniques qui lui sont indispensables. Elle suppose la sagesse d'admettre les pesanteurs, la complexité et la relativité de la vie, ainsi que la sérénité d'accepter ce qui ne peut être changé, le courage de modifier ce qui peut l'être et le désir de chercher à distinguer l'un de l'autre sans parti-pris. Ceci requiert une tournure d'esprit et une culture à laquelle il ne paraît pas concevable d'accéder sans le secours de l'expérience et le recours à l'histoire. (shrink)

Dans un monde dominé par les conflits, il arrive qu’il faille se défendre. L’invention des armes a évolué en parallèle avec le savoir technique, puis scientifique, et il est même arrivé que la recherche d’applications militaires ait joué un rôle moteur dans la découverte scientifique. Lorsque les armes ne servent pas à attaquer d’autres nations, leur fabrication et leur commerce se justifient morale- ment. Il faut cependant qu’elles ne puissent échapper à ceux qui les construisent et doivent en contrôler la (...) diffusion. Facilement mise en œuvre, la guerre utilisant des organismes vivants ou ce qu’ils pro- duisent comme armes est très ancienne. Or l’originalité des êtres vivants est qu’ils se multiplient, qu’un seul individu suffit à recouvrir la Terre de ses descendants. La biologie ne se prête jamais à un usage militaire moralement défendable parce que le confinement au champ de bataille est impossible. De ce fait, les applications de la biologie ont été vite écartées du domaine de la Défense permise par les traités internationaux. La Convention de 1972 sur l’Interdiction des Armes Biologiques et à Toxines (CIABT), entrée en vigueur en 1975, est aujourd’hui signée par 183 pays (ratifiée par 175) sur un total de 193, sans compter Taïwan qui l’a ratifiée mais n’est pas reconnu par l’ONU. Elle interdit la mise au point, la fabrication, l’acquisition, le transfert, la conservation, le stockage et l’utilisation des armes bio- logiques et à toxines. Elle constitue un élément essentiel de la lutte contre la prolifération des armes de destruction massive. (shrink)

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_sciousness called ‘neurophenomenology’ (Varela 1996) and illustrates it with a_ _recent pilot study (Lutz et al., 2002). At a theoretical level, neurophenomenology_ _pursues an embodied and large-scale dynamical approach to the_ _neurophysiology of consciousness (Varela 1995; Thompson and Varela 2001;_ _Varela and Thompson 2003). At a methodological level, the neurophenomeno-_ _logical strategy is to make rigorous and extensive use of first-person data about_ _subjective experience as a heuristic to describe and quantify the large-scale_ _neurodynamics of consciousness (Lutz 2002). The paper (...) foocuses on_ _neurophenomenology in relation to three challenging methodological issues_ _about incorporating first-person data into cognitive neuroscience: (i) first-person_ _reports can be biased or inaccurate; (ii) the process of generating first-person_ _reports about an experience can modify that experience; and (iii) there is an ‘ex-_ _planatory gap’ in our understanding of how to relate first-person, phenomeno-_ _logical data to third-person, biobehavioural data._. (shrink)

Recent brain imaging studies using functional magnetic resonance imaging (fMRI) have implicated insula and anterior cingulate cortices in the empathic response to another’s pain. However, virtually nothing is known about the impact of the voluntary generation of compassion on this network. To investigate these questions we assessed brain activity using fMRI while novice and expert meditation practitioners generated a loving-kindness-compassion meditation state. To probe affective reactivity, we presented emotional and neutral sounds during the meditation and comparison periods. Our main hypothesis (...) was that the concern for others cultivated during this form of meditation enhances affective processing, in particular in response to sounds of distress, and that this response to emotional sounds is modulated by the degree of meditation training. The presentation of the emotional sounds was associated with increased pupil diameter and activation of limbic regions (insula and cingulate cortices) during meditation (versus rest). During meditation, activation in insula was greater during presentation of negative sounds than positive or neutral sounds in expert than it was in novice meditators. The strength of activation in insula was also associated with self-reported intensity of the meditation for both groups. These results support the role of the limbic circuitry in emotion sharing. The comparison between meditation vs. rest states between experts and novices also showed increased activation in amygdala, right temporo-parietal junction (TPJ), and right posterior superior temporal sulcus (pSTS) in response to all sounds, suggesting, greater detection of the emotional sounds, and enhanced mentation in response to emotional human vocalizations for experts than novices during meditation. Together these data indicate that the mental expertise to cultivate positive emotion alters the activation of circuitries previously linked to empathy and theory of mind in response to emotional stimuli.. (shrink)