Emotional processing and episodic memory are closely related throughout childhood development. With respect to emotional episodic memory, available evidence shows that the consolidation of information is accompanied by an arousal that generates longer duration and persistence of the memory representations. In the case of early stages of development (i.e., first 5 years), it is less clear how these associations emerge and are modulated by individual and environmental factors. In this study, 116 4- to 5-years old Argentinean children from (...) different socio-environmental contexts (i.e., favorable or unfavorable living conditions at home), performed a task of visual emotional memory in which they observed a set of 15 images with variable emotional valences (negative, neutral, and positive). The child’s task was to appraise each image using one of the following three possible valences: (a) drawings of faces with smiles (positive valence), (b) drawings of faces with tears and round mouth with edges down (negative valence), or (c) drawings of faces with horizontal mouth (neutral valence). Five years-old children exhibited greater accuracy appraisal. Individual differences in emotional accuracy appraisal allowed us to observe different performances in free recall of negative visual images. Accuracy appraisal did not vary between children with respect to gender, living conditions at home, or language ability. Seven to ten days after the emotional appraisal children were asked to tell the experimenter all the images they remembered (variables of interest: free recall of negative, positive, or neutral images). Results showed individual (age) differences. Specifically, 5-years-old children evoked more images than 4-years-old children. These findings contribute to the understanding of emotional memory in early developmental stages and raise the need to include emotional appraisal in the assessment of episodic memory. (shrink)

Objective: The dopamine hypothesis is one of the most influential theories of the neurobiological background of schizophrenia (SCZ). However, direct evidence for abnormal dopamine-related subcortical-cortical circuitry disconnectivity is still lacking. The aim of this study was therefore to test dopamine-related substantia nigra (SN)-based striato-thalamo-cortical resting-state functional connectivity (FC) in SCZ. Method: Based on our a priori hypothesis, we analyzed a large sample resting-state functional magnetic resonance imaging (fMRI) dataset from first-episode drug-naïve SCZ patients (n = 112) and healthy controls (n (...) = 82) using the SN as the seed region for an investigation of striato-thalamo-cortical FC. This was done in the standard band of slow frequency oscillations and then in its subfrequency bands (Slow4 and Slow5). Results: The analysis showed in SCZ: (1) reciprocal functional hypo-connectivity between SN and striatum, with differential patterns for Slow5 and Slow4; (2) functional hypo-connectivity between striatum and thalamus, as well as functional hyper-connectivity between thalamus and sensorimotor cortical areas, specifically in Slow4; (3) correlation of thalamo-sensorimotor functional hyper-connectivity with psychopathological symptoms. Conclusions: We demonstrate abnormal dopamine-related SN-based striato-thalamo-cortical FC in slow frequency oscillations in first-episode drug-naive SCZ. This suggests that altered dopaminergic function in the SN leads to abnormal neuronal synchronization (as indexed by FC) within subcortical-cortical circuitry, complementing the dopamine hypothesis in SCZ on the regional level of resting-state activity. (shrink)

The goal of the present study was to examine the hypothesis that the ability to construct vivid mental images of the future involves sampling the contents of memory. In two experiments, participants envisioned future scenarios occurring in contextual settings that were represented in memory in varying degrees of perceptual detail. In both experiments, detailed contextual settings were associated with more detailed images of the future and a stronger subjective experience. Our findings suggest that the contents of memory are routinely (...) sampled during the construction of personal future scenarios. (shrink)

This study explored spatial navigation alongside several other cognitive abilities that are thought to share common underlying neurocognitive mechanisms (e.g., the capacity for self-projection, scene construction, or mental simulation), and which we hypothesised may be impaired in autism spectrum disorder (ASD). Twenty intellectually high-functioning children with ASD (with a mean age of ~8 years) were compared to 20 sex, age, IQ, and language ability matched typically developing children on a series of tasks to assess spatial navigation, episodic memory, (...) class='Hi'>episodic future thinking (also known as episodic foresight or prospection), theory of mind, relational memory, and central coherence. This is the first study to explore these abilities concurrently within the same sample. Spatial navigation was assessed using the “memory island” task, which involves finding objects within a realistic, computer simulated, three-dimensional environment. Episodic memory and episodic future thinking were assessed using a past and future event description task. Theory of mind was assessed using the “animations” task, in which children were asked to describe the interactions between two animated triangles. Relational memory was assessed using a recognition task involving memory for items (line drawings), patterned backgrounds, or combinations of items and backgrounds. Central coherence was assessed by exploring differences in performance across segmented and unsegmented versions of block design. Children with ASD were found to show impairments in spatial navigation, episodic memory, episodic future thinking, and central coherence, but not theory of mind or relational memory. Among children with ASD, spatial navigation was found to be significantly negatively related to number of repetitive behaviours. In other words, children who showed more repetitive behaviours showed poorer spatial navigation. The theoretical and practical implications of the results are discussed. (shrink)

Autobiographical memories of older adults show fewer episodic and more non-episodic elements than those of younger adults. This semantization effect is attributed to a loss of episodic memory ability. However the alternative explanation by an increasing proclivity to search for meaning has not been ruled out to date. To test whether a decrease in episodicity and an increase in meaning-making in autobiographical narratives are related across the lifespan, we used different instructions, one focussing on specific episodes, the (...) other on embedding events in life, in two lifespan samples. A continuous decrease of episodic quality of memory was confirmed. An increase of search for meaning was confirmed only up to middle adulthood. This non-inverse development of episodicity and searching for meaning in older age speaks for an autonomous semantization effect that is not merely due to an increase in interpretative preferences. (shrink)

In four studies, we examine the “LIFE IS A JOURNEY” conceptual metaphor using as data output from semantic and episodic memory. In the first three studies output from semantic memory indicates that undergraduate samples, when primed to think in “LIFE” in terms of a course followed until one's 70th year, provided a set of events output in a sequential order and when compared to a second sample, showed high agreement on the ages in which the events would occur. These (...) data were taken as supportive of a “JOURNEY” metaphor in which one progressed along a life path. Study 2 indicated that the “LIFE” events produced also aroused specific subthemes, consistent with the notion of the arousal of lower-level “LIFE-JOURNEY” metaphors (e.g., “LOVE IS A JOURNEY”). In a third study, we experimentally constrained the order of report from semantic memory. These data indicate that free output of events (as in Study 1) involves both a forward-temporal output, and clustering of life themes, but that forcing a forward-temporal order is indicative of the arousal of the superordinate conceptual metaphor but not the lower-level themes. Finally, in an episodic memory task one finds the reverse, namely arousal of the lower-level themes but not of the superordinate conceptual metaphor. Taken together, these findings indicate conditions under which the “LIFE IS A JOURNEY” metaphor is facilitated, and when lower-level metaphors are made more salient. In a more general way, the studies provide a new tool with which to study conceptual metaphors. (shrink)

In the course of his chemical investigation of crude platina ore, William Hyde Wollaston in 1802 isolated and characterized the metal palladium. In early 1803, he chose to make known his discovery by offering small samples of the metal for sale through a small shop in London. In the notice advertising the properties of the new metal, no information was given as to its source nor to its discoverer. The unique properties of the metal, and the secrecy surrounding its discovery, (...) led the Irish chemist Richard Chenevix to question the elemental nature of the new metal. His hasty but extensive investigation of the chemical properties of palladium convinced him that it was no more than an alloy of platinum and mercury, and he denounced the discovery as fraudulent. The president of the Royal Society, Joseph Banks, was drawn into the resulting furore, and correspondence between him and Chenevix reveals involved plans to obtain the identity of the palladium discoverer. The controversy is viewed as a significant episode in the continuing debate in the chemical community over the operational definition of a chemical element, and although Chenevix's concern over the growth in the number of new elements was justified, his choice of palladium as a test case was an unfortunate one, for his claim that the metal was an alloy was found to be erroneous. Motives for the actions of both Chenevix and Wollaston are sought, and the judgement that their careers were damaged by the incident is questioned. (shrink)

Exploitation locates what it is we recognize as bad when we judge a situation to be exploitative. Ideal for courses in social and political philosophy, public policy, or political science.

This paper aims to resolve an unremarked-upon tension between Anne Conway’s commitment to the moral responsibility of created beings, or creatures, and her commitment to emanative, constant creation. Emanation causation has an atemporal aspect according to which God’s act of will coexists with its effect. There is no before or after, or past or future in God’s causal contribution. Additionally, Conway’s constant creation picture has it that all times are determined via divine emanation. Creaturely agency, by contrast, is fundamentally temporal, (...) occurring successively over time. It is unclear how creatures can count as emanative causes, which coexists with its effect, given that their agency is limited by time, proceeding from before to after, or past to future. Conway’s account of divine justice in the progress of time, however, requires that creatures are causally responsible. That is, moral responsibility requires causal responsibility. I propose that Conway’s distinction between vital motion and local motion enables a resolution of the tension. Vital motion contributes an atemporal aspect to creaturely agency so that creatures can count as secondary emanative causes. (shrink)

If we cannot define science using only analysis or description, then we must rely on imagination to provide us with suitable objects of philosophical inquiry. This process ties our intellectual findings to the particular ways in which we philosophers think about scientific practice and carve out a cognitive space between real world practice and conceptual abstraction. As an example, I consider Heather Douglas’s work on the responsibilities of scientists and document her implicit ideal of science, defined primarily as an epistemic (...) practice. I then contrast her idealization of science with an alternative: “technoscience,” a heuristic concept used to describe nanotechnology, synthetic biology, and similar “Mode 2” forms of research. This comparison reveals that one’s preferred imaginary of science, even when inspired by real practices, has significant implications for the distribution of responsibility. Douglas’s account attributes moral obligations to scientists, while the imaginaries associated with “technoscience” and “Mode 2 science” spread responsibility across the network of practice. This dynamic between mind and social order, I argue, demands an ethics of imagination in which philosophers of science hold themselves accountable for their imaginaries. Extending analogous challenges from feminist philosophy and Mills’s. “Ideal Theory’ as Ideology,” I conclude that we ought to reflect on the idiosyncrasy of the philosophical imagination and consider how our idealizations of science, if widely held, would affect our communities and broader society. (shrink)

Since the 1960s, scientists, engineers, and healthcare professionals have developed brain–computer interface (BCI) technologies, connecting the user’s brain activity to communication or motor devices. This new technology has also captured the imagination of publics, industry, and ethicists. Academic ethics has highlighted the ethical challenges of BCIs, although these conclusions often rely on speculative or conceptual methods rather than empirical evidence or public engagement. From a social science or empirical ethics perspective, this tendency could be considered problematic and even technocratic because (...) of its disconnect from publics. In response, our trinational survey (Germany, Canada, and Spain) reports public attitudes toward BCIs (N = 1,403) on ethical issues that were carefully derived from academic ethics literature. The results show moderately high levels of concern toward agent-related issues (e.g., changing the user’s self) and consequence-related issues (e.g., new forms of hacking). Both facets of concern were higher among respondents who reported as female or as religious, while education, age, own and peer disability, and country of residence were associated with either agent-related or consequence-related concerns. These findings provide a first look at BCI attitudes across three national contexts, suggesting that the language and content of academic BCI ethics may resonate with some publics and their values. (shrink)

Kyle Stanford’s reformulation of the problem of underdetermination has the potential to highlight the epistemic obligations of scientists. Stanford, however, presents the phenomenon of unconceived alternatives as a problem for realists, despite critics’ insistence that we have contextual explanations for scientists’ failure to conceive of their successors’ theories. I propose that responsibilist epistemology and the concept of “role oughts,” as discussed by Lorraine Code and Richard Feldman, can pacify Stanford’s critics and reveal broader relevance of the “new induction.” The possibility (...) of unconceived alternatives pushes us to question our contemporary expectation for scientists to reason outside of their historical moment. (shrink)

Promising new solutions or risking unprecedented harms, science and its technological affordances are increasingly portrayed as matters of global concern, requiring in-kind responses. In a wide range of recent discourses and global initiatives, from the International Summits on Human Gene Editing to the Intergovernmental Panel on Climate Change, experts and policymakers routinely invoke cosmopolitan aims. The common rhetoric of a shared human future or of one humanity, however, does not always correspond to practice. Global inequality and a lack of accountability (...) within most institutional contexts of international governance render these cosmopolitan proclamations of ‘one human community’ incoherent and even harmful. More generally, there exists no shared normative standard for the cosmopolitan governance of science, with which such global initiatives could be evaluated. Taking a broadly philosophical perspective, the present paper aims to better understand this problem situation, identifying three high-level challenges global governance of technoscience: problematic ideals of technology and science, the unjust formation of “global” concerns, and the limitations of cosmopolitan theory. By holistically engaging these jointly empirical and normative sites of inquiry, scholars can better support humanity’s re-imagination of technoscientific practices within and beyond the nation-state. (shrink)

Scientists, engineers, and healthcare professionals are currently developing a variety of new devices under the category of brain-computer interfaces (BCIs). Current and future applications are both medical/assistive (e.g., for communication) and non-medical (e.g., for gaming). This array of possibilities comes with ethical challenges for all stakeholders. As a result, BCIs have been an object of both hope and concern in various media. We argue that these conflicting sentiments can be productively understood in terms of personhood, specifically the impact of BCIs (...) on what it means to be a person and to be recognized as such by others. To understand the dynamics of personhood in the context of BCI use and investigate whether ethical guidance is required, a meeting entitled "BCIs and Personhood: A Deliberative Workshop" was held in May 2018. In this article, we describe how BCIs raise important questions about personhood and propose recommendations for BCI development and governance. (shrink)

What are philosophers doing when they prescribe a particular epistemology for science? According to science and technology studies, the answer to this question implicates both knowledge and politics, even when the latter is hidden. Exploring this dynamic via a specific case, I argue that Longino’s “critical contextual empiricism” ultimately relies on a form of political liberalism. Her choice to nevertheless foreground epistemological concerns can be clarified by considering historical relationships between science and society, as well as the culture of academic (...) philosophy. This example, I conclude, challenges philosophers of science to consider the political ideals and accountability entailed by their prescribed knowledge practices. (shrink)

Ankeny and Leonelli propose “repertoires” as a new way to understand the stability of certain research programs as well as scientific change in general. By bringing a more complete range of social, material, and epistemic elements into one framework, they position their work as a correction for the Kuhnian impulse in philosophy of science and other areas of science studies. I argue that this “post-Kuhnian” move is not complete, and that repertoires maintain an internalist perspective, caused partly by an asymmetrical (...) emphasis on the scientists’ side of practice. If we compare “repertoires” to alternative frameworks, like “sociotechnical imaginaries” of Jasanoff and Kim, it is evident that repertoires are missing two specific things. First, I argue that the framework needs to include the role of audience, without whom the repertoires of science are unintelligible. Second, I suggest that the framework also lacks an explicit place for ethical and political imagination, which provide meaning for otherwise mechanical promotion of particular research programs. With these modifications, Ankeny and Leonelli’s framework might fulfill its post-Kuhnian potential. (shrink)

ABSTRACT: Simon Baron-Cohen has argued that autism and related developmental disorders (sometimes called “autism spectrum conditions” or “autism spectrum disorders”) can be usefully thought of as the condition of possessing an “extreme male brain.” The impetus for regarding autism spectrum disorders (ASD) this way has been the accepted science regarding the etiology of autism, as developed over that past several decades. Three important features of this etiology ground the Extreme Male Brain theory. First, ASD is disproportionately male (approximately 10:1 in (...) the case of Asperger’s Syndrome or high-functioning autism (HFA) and approximately 4:1 in the case of autistic disorder). Second, ASD is not psychogenic but biological in origin, and hence is not the product of sexist conditioning or childrearing practices, although these may affect the development of the disorder. Third, ASD is regarded as a spectrum developmental disorder, unlike other disorders such as Down Syndrome that are diagnosed by a (nearly) binary criterion. Down Syndrome, for example, is diagnosed by the presence in all or most cells within a given individual of an extra copy of Chromosome 21. Autism, on the other hand, is diagnosed by the presence of a set of symptoms that vary in their intensity and in their milder forms seem to conform to purported sex differences in cognitive, emotional, and social functioning. -/- In this paper, I do not challenge accepted science regarding the etiology of autism, and I do not challenge the idea of ASD as a disorder. Nor do I wish to offer an alternative account of what autism is. Instead, I focus on the usefulness of thinking of a disorder as an extreme version of ordinary sex differences. Does it follow from the fact that a disorder is more often found in men that we should think of it as an extreme form of maleness? If not, what other conditions must be met in order to warrant this way of thinking about ASD? What does it mean to say that ASD is a form of “extreme male brain”? Feminists are rightly skeptical of theories that make claims about male and female brains, so how should we respond to the clear evidence that the differences between typical and ASD individuals are not caused by childrearing practices? I explain what I take to be Baron-Cohen’s central argument that autism should be seen as the extreme male brain, and critique that argument. I conclude that there is no good argument that autistic symptoms should be regarded as an extreme form of male mental traits, and that Baron-Cohen’s claim does not help us to understand autism, women, or men. His claim is a speculative thesis that is readily mobilized for sexist practices. As such it requires a higher threshold for evidentiary support and rigorous argumentation—support and argumentation that does not exist. -/- KEYWORDS: autism, brain, gender, neuroscience, feminism, male . (shrink)

Anne Conway’s commitment to the moral responsibility of creatures, or created beings, is seemingly in tension with her unique metaphysics. Conway is committed to individual moral responsibility. Conway insists that an innocent person ought not be punished for someone else’s sin. Interesting recent work highlights a unique aspect of Conway’s position that creatures are multiplicities: not only are creatures integrated into the larger whole of creation, but also their parts are mutually integrated into one another. The latter, which I will (...) call ‘ontological overlap,’ renders the boundaries between creatures unclear. However, creatures must be distinct enough from each other to provide a proper subject for individual moral responsibility. This contribution suggests that Conway’s account of vital power can resolve an apparent tension between ontological overlap and individual moral responsibility and, more broadly, that Conway has a relational metaphysics of moral subjecthood. (shrink)

When interpreters orient Kant’s philosophy of time in relation to McTaggart’s distinction among different ways of characterizing a temporal order, they claim that he is best described as endorsing an A series position according to which there is a metaphysically privileged present that determines the past and the future. Whether Kant might also be understood as a proponent of the B series - according to which there is no privileged present, but rather time is comprised of relations of earlier than, (...) later than, and simultaneity - has not been discussed in the literature. I argue that, for Kant, the appearances can be described as an A series, while the phenomena are to be understood as a B series, neither of which is more fundamental than the other. Contra a common approach in the literature that neglects a metaphysical difference between appearances and phenomena, I argue Kant’s transcendental idealism about time is best understood in relation to his account of appearances and phenomena. (shrink)

Declaring a cosmopolitan right to scientific progress risks perpetuating many of the inequities it aims to overcome. This calls for a re-imagination of science that directly responds to science’s links to violent nationalist projects and the harms of capitalism.

This paper makes explicit some issues of gender that have been implicitly raised in recent discussions concerning the recovery of European women's contributions to the history of seventeenth‐ and eighteenth‐century philosophy. A useful way to bring these issues to light is to distinguish between the project of recovering women's contributions and the project of justifying their inclusion. The former project is an important effort to provide a more accurate understanding of the history of philosophy. Within the latter project, there is (...) a distinction between justifying the inclusion of a specific author and justifying women's inclusion in general. The suggestion that we need to justify women's inclusion in general is fundamentally illegitimate because it presumes that either women's philosophical ability is up for debate or that their contributions require special explanation, both of which are misogynist. (shrink)

Conway characterizes freedom in apparently contradictory ways. She describes God as the most free, yet he is necessitated to act perfectly due to his wisdom and goodness. Created beings, by contrast, sin. They are not necessitated to do so. This suggests that Conway has a binary account of freedom: divine freedom is a matter of being necessitated by wisdom and goodness, whereas creaturely freedom consists in indifference, understood as a power to act, or not act. Despite the apparently conflicting remarks, (...) I argue that Conway has a single account of freedom as spontaneity. Conway defines spontaneity in terms of causing one’s own action independent of external causes. I suggest that spontaneity is more precisely understood as an intrinsic power aimed at the good in Conway’s metaphysics, and that this account of freedom can combine necessity and contingency. Rather than a binary, Conway offers an account of freedom in creation that has it on a continuum with divine freedom. (shrink)

When interpreters orient Kant in relation to contemporary philosophy of time, they claim that the B series is dependent on the A series. However, I claim that the opposite direction of dependence is also supported, due to Kant’s position that change is both intelligible and involves incompatibility. This paper extends the contemporary description of Kant’s philosophy of time to show that Kant endorses the interdependence of A series and B series views on time.

Kant’s ethics provides surprising resources for addressing duties with respect to climate change. First, I show how Kant’s moral metaphysics, according to which the self is a phenomenon, provides a distinctive ground to mitigate the harm of climate change for future generations. In short, the physical appearances of our actions are grounded in an atemporal existence from which our intrinsic moral value derives. As such, the a priori basis for addressing climate duties to the present is no different from that (...) of duties to address climate duties to the future, though we must consider present circumstances in order to act effectively. Second, I show that recent helpful contributions towards understanding the resources of Kantian ethics for addressing climate face the following prima facie dilemma: perfect duties to reduce emissions are overly demanding because it requires reduction below subsistence levels, while imperfect duties to reduce emissions are not demanding enough to address the climate crisis. Without ruling out the existence of perfect duties to address climate, I analyze the latter horn of the dilemma and show how imperfect duties can be more demanding than one might have thought, given that we are in a climate emergency. Recent work on the role of emergency in Kant’s ethics has shown that there are resources for making sense of the prioritization of some concerns as more pressing. Overall, the aim of this contribution is to highlight some of the prospects and problems that face Kantian approaches to climate ethics. (shrink)

Nearly everyone agrees that sexual exploitation occurs and that, when it does, it is morally wrong. However, there is substantial disagreement over what constitutes sexual exploitation and why it is wrong. Is sex between freely consenting adults ever exploitative? Is prostitution always exploitative? What features of sexually exploitative interactions lead us to regard them as morally wrong? And if sexual exploitation is morally wrong, what should be done about it?These are not new questions for the social philosopher. However, recent criticisms (...) of social contract theory may lead us to wonder whether contractarianism has the resources to criticize important cases of sexual exploitation—particularly prostitution. Some liberals have defended prostitution “in principle,” arguing that when prostitution is truly consensual, there is nothing wrong with it. This is called “sound prostitution.” Indeed, in cases where the parties to a sexual exchange are both competent adults, liberals and libertarians have a difficult time criticizing it, since to do so runs the risk of imposing a local and historically specific sexual ideal on members of society who explicitly reject it or else suggests that the prostitutes and their clients are not really competent agents. (shrink)

In Exploitation: What It Is and Why It's Wrong (2003), I argued that the major non‐Marxist “ethically thick” approaches to exploitation were not successful in capturing what we find morally objectionable in paradigmatic cases of exploitation. My argument there focused on the consequentialist account of exploitation defended by Robert Goodin. Here I revisit the question of whether the recent multi‐level act consequentialist account of exploitation defended by Richard Arneson is successful. I raise questions about the nature of the account, and (...) conclude that it is a possibly coherent and ultimately inadequate account of the wrongness of exploitation. (shrink)

The misleading and propagandistic tendencies in American news reporting have been a part of public discussion from its earliest days as a republic (Innis, 2007;Sheppard, 2007). “Fake news” is hardly new (McKernon, 1925), and the term has been applied to a variety of distinct phenomenon ranging from satire to news, which one may find disagreeable (Jankowski, 2018;Tandoc et al., 2018). However, this problem has become increasingly acute in recent years with the Macquarie Dictionary declaring “fake news” the word of the (...) year in 2016 (Lavoipierre, 2017). The international recognition of fake news as a problem (Pomerantsev and Weiss, 2014;Applebaum and Lucas, 2016) has led to a number of initiatives to mitigate perceived causes, with varying levels of success (Flanagin and Metzger, 2014;Horne and Adali, 2017;Sample et al., 2018). The inability to create a holistic solution continues to stymie researchers and vested parties. A significant contributor to the problem is the interdisciplinary nature of digital deception. While technology enables the rapid and wide dissemination of digitally deceptive data, the design and consumption of data rely on a mixture of psychology, sociology, political science, economics, linguistics, marketing, and fine arts. The authors for this effort discuss deception’s history, both old and new, from an interdisciplinary viewpoint and then proceed to discuss how various disciplines contribute to aiding in the detection and countering of fake news narratives. A discussion of various fake news types (printed, staged events, altered photographs, and deep fakes) ensues with the various technologies being used to identify these; the shortcomings of those technologies and finally the insights offered by the other disciplines can be incorporated to improve outcomes. A three-point evaluation model that focuses on contextual data evaluation, pattern spread, and archival analysis of both the author and publication archives is introduced. While the model put forth cannot determine fact from fiction, the ability to measure distance from fact across various domains provides a starting point for evaluating the veracity of a new story. (shrink)

Ranging from miniaturized biological robots to organoids, multi-cellular engineered living systems (M-CELS) pose complex ethical and societal challenges. Some of these challenges, such as how to best distribute risks and benefits, are likely to arise in the development of any new technology. Other challenges arise specifically because of the particular characteristics of M-CELS. For example, as an engineered living system becomes increasingly complex, it may provoke societal debate about its moral considerability, perhaps necessitating protection from harm or recognition of positive (...) moral and legal rights, particularly if derived from cells of human origin. The use of emergence-based principles in M-CELS development may also create unique challenges, making the technology difficult to fully control or predict in the laboratory as well as in applied medical or environmental settings. In response to these challenges, we argue that the M-CELS community has an obligation to systematically address the ethical and societal aspects of research and to seek input from and accountability to a broad range of stakeholders and publics. As a newly developing field, M-CELS has a significant opportunity to integrate ethically responsible norms and standards into its research and development practices from the start. With the aim of seizing this opportunity, we identify two general kinds of salient ethical issues arising from M-CELS research, and then present a set of commitments to and strategies for addressing these issues. If adopted, these commitments and strategies would help define M-CELS as not only an innovative field, but also as a model for responsible research and engineering. (shrink)

Headlines in 2019 are inundated with claims about the “digital society,” making sweeping assertions of societal benefits and dangers caused by a range of technologies. This situation would seem an ideal motivation for ethics research, and indeed much research on this topic is published, with more every day. However, ethics researchers may feel a sense of déjà vu, as they recall decades of other heavily promoted technological platforms, from genomics and nanotechnology to machine learning. How should ethics researchers respond to (...) the waves of rhetoric and accompanying academic and policy-oriented research? What makes the digital society significant for ethics research? In this paper, we consider two examples of digital technologies (artificial intelligence and neural technologies), showing the pattern of societal and academic resources dedicated to them. This pattern, we argue, reveals the jointly sociological and ethical character of significance attributed to emerging technologies. By attending to insights from pragmatism and science and technology studies, ethics researchers can better understand how these features of significance affect their work and adjust their methods accordingly. In short, we argue that the significance driving ethics research should be grounded in public engagement, critical analysis of technology’s “vanguard visions,” and in a personal attitude of reflexivity. (shrink)

Title: Political Theology Publisher: The MIT Press ISBN: 0262192446 Author: Carl Schmitt Title: The Crisis of Parliamentary Democracy Publisher: The MIT Press ISBN: 0262691264 Author: Carl Schmitt.

If we cannot define science using only analysis or description, then we must rely on imagination to provide us with suitable objects of philosophical inquiry. This process links our findings to the particular ways in which we philosophers idealize scientific practice and carve out an experimental space between real world practice and thought experiments. As an example, I examine Heather Douglas’ recent work on the responsibilities of scientists and contrast her account of science with that of “technoscience,” as mobilized in (...) nanotechnology, synthetic biology, and similar control-oriented fields. The difference between the two idealizations of science reveals that one’s preferred imaginary of science, even when inspired by real practices, has real implications for the distribution of responsibility. Douglas’ account attributes moral obligations to scientists, while a framework of “technoscience” spreads responsibility across the network of practice. I use this case to call for an ethics of imagination, in which philosophers of science hold themselves accountable for their imaginaries. We ought reflect on the idiosyncrasy of the philosophical imagination and consider how our idealizations, if widely held, would affect our fellow citizens. (shrink)

The ultimate aim of this dissertation is to determine whether libertarian theories of property can be adequately grounded in Locke's theory of natural rights. I defend the thesis that Locke's theory has no room for a fundamental commitment to natural rights, including property rights. ;In the first three chapters, I challenge each component of the dominant interpretation of Locke's theory of property in this century, viz., that of C. B. Macpherson. In Chapter One, I criticize Macpherson's claim that Locke's view (...) allows unlimited appropriation. In Chapter Two, I agree with Macpherson that Locke defended a state in which the franchise was restricted to those who held significant property, viz., land. However, this can be reconciled with an initial contract into civil society that meets certain standards of rationality and fairness. Thus, while political power is not equally distributed in the state Locke describes, that is not necessarily inconsistent with a rational, free, and voluntary social contract. This shows that we need not see Locke as committed to the interests of the wealthiest members of society. In Chapter Three, I agree with Macpherson that Locke's view is that the purpose of contracting out of the state of nature is the protection of one's property. But I briefly argue that Macpherson does not take seriously Locke's concept of property right and the wide range of objects that count as property. If we pay careful attention to Locke's terminology, we can see that although the purpose of the state is the protection of property, that does not guarantee greater protection for the wealthy than it ensures the poor. ;In Chapter Four, I challenge a quite different thesis. James Tully has argued that Locke did not defend private property at all, but attacked it. I criticize this interpretation on the grounds that Locke explicitly allows certain practices that Tully takes to be violations of the law of nature as Locke construes it. I also criticize the claim that certain developments in a commercial economy, such as the consumption of valuable land, necessarily violate the law of nature. In addition, I argue that the idea of conventionally established property rights is inconsistent with Locke's account of how and why government comes to be established. ;In Chapter Five, I provide an account of the principles underlying Locke's account of rights, both within and without civil society. I argue that Locke's view is improperly construed as a view which gives pride of place to rights. Rather, rights are almost always derivative from duties, and in those cases where they are not derivative, they are subordinate to certain primary duties that oblige us in virtue of our status as God's creations. (shrink)