Drawing on and extending the Foucaultian philosophical framework that Jeffrey Bishop develops in his masterful book, The Anticipatory Corpse: Medicine, Power, and the Care of the Dying, we undertake a sociological analysis of the neurological procedure—deep brain stimulation —which implants electrodes in the brain, powered by a pacemaker-like device, for the treatment of movement disorders. Following Bishop’s work, we carry out this analysis through a two-fold strategy. First, we examine how a multidisciplinary team evaluates candidates for this implant at a (...) major medical center. We present excerpts from an ethnographic study of the “case conference” where disease entities are presented, contested, ratified, and made objects for intervention with this technology. The case conference becomes the key site in the transition from “person-with-illness” to “person-with-brain-implant” as a team of health professionals determines a plan of action by interpreting both statistical and “quality of life” data regarding their patients. Second, this article explores these decision-making processes through Bishop’s conceptualization of evidence-based medicine, which relies on statistical approaches as the ultimate authority in knowledge production and medical decisions. We then reflect on Bishop’s critique of the social sciences and the methodological, analytical, and substantive ramifications that The Anticipatory Corpse can offer future sociological work. (shrink)

Joan Tronto’s new paradigm of caring democracy bases citizenship on the need to ensure that all people receive and provide care equitably. But how exactly are citizens motivated to take up these caring responsibilities? The writings of Alcoholics Anonymous (AA) co-founder William ‘Bill’ Wilson provide one answer: he pathologizes the alcoholic – dooming him to inevitable relapse and death – to compel AA members to accept shared vulnerability and mutual care as the bedrock of sobriety and AA society. Wilson returns (...) repeatedly to the threat of death to convince AA members to carry out their newfound caring and democratic responsibilities. We use Wilson’s thinking, as well as Michel Foucault’s work on biopower, to forward the concept of biocaring democracy, in which the acceptance of shared pathology compels people to care for each other but also limits their democratic responsibilities. More broadly, our analysis suggests how hinging democracy to shared vulnerability may constrain the radical possibilities that Tronto envisions. (shrink)

Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

BackgroundThe ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are widely endorsed but compliance is limited. We sought to determine whether journal-requested completion of an ARRIVE checklist improves full compliance with the guidelines.MethodsIn a randomised controlled trial, manuscripts reporting in vivo animal research submitted to PLOS ONE (March–June 2015) were randomly allocated to either requested completion of an ARRIVE checklist or current standard practice. Authors, academic editors, and peer reviewers were blinded to group allocation. Trained reviewers performed outcome adjudication (...) in duplicate by assessing manuscripts against an operationalised version of the ARRIVE guidelines that consists 108 items. Our primary outcome was the between-group differences in the proportion of manuscripts meeting all ARRIVE guideline checklist subitems.ResultsWe randomised 1689 manuscripts (control: n = 844, intervention: n = 845), of which 1269 were sent for peer review and 762 (control: n = 340; intervention: n = 332) accepted for publication. No manuscript in either group achieved full compliance with the ARRIVE checklist. Details of animal husbandry (ARRIVE subitem 9b) was the only subitem to show improvements in reporting, with the proportion of compliant manuscripts rising from 52.1 to 74.1% (X2 = 34.0, df = 1, p = 2.1 × 10−7) in the control and intervention groups, respectively.ConclusionsThese results suggest that altering the editorial process to include requests for a completed ARRIVE checklist is not enough to improve compliance with the ARRIVE guidelines. Other approaches, such as more stringent editorial policies or a targeted approach on key quality items, may promote improvements in reporting. (shrink)

From Nietzsche's early writings to those marking the end of his intellectual life, the dynamics of what he called "physiology" permeate virtually every facet of his philosophical enterprise. In the following investigation, these dynamics are explored as an interpretive key to not only the dominant themes but also the philosophical motive underlying Nietzsche's philosophy. This motive is described in terms of his diagnosis and attempted cure for the disease of nihilism. In this we maintain that Nietzsche's foremost philosophical task is (...) that of a cultural physician. ;In pursuit of this theme, Nietzsche's "clinical standpoint" is explored and applied with regard to Socrates and Jesus Christ as two case studies in decadence. These two "cases" are a simultaneous physiological investigation into both the ancient Greek and Hebrew cultures. ;This investigation concludes with a detailed analysis of the physiological significance of the Revaluation of all Values, Eternal Recurrence, the Overman and Dionysus as integral to curing the sickness of nihilism. (shrink)

The fundamental postulate of sociobiology is that individuals exploit favorable environments to increase their genetic representation in the next generation. The data on fertility differentials among contemporary humans are not cotvietent with this postulate. Given the importance ofHomo sapiensas an animal species in the natural world today, these data constitute particularly challenging and interesting problem for both human sociobiology and sociobiology as a whole.The first part of this paper reviews the evidence showing an inverse relationship between reproductive fitness and “endowment” (...) in contemporary, urbanized societies. It is shown that a positive relationship is observed only for those cohorts who bore their children during a unique period of rising fertility, 1935–1960, and that these cohorts are most often cited by sociobiologists as supporting the central postulate of sociobiology. Cohorts preceding and following these show the characteristic inverse relationship between endowment and fertility. The second section reviews the existing so-ciobiological models of this inverse relationship, namely, those of Barkow, Burley, and Irons, as well as more informal responses among sociobiologists to the persistent violation of sociobiology's central postulate, such as those of Alexander and Dawkins. The third section asks whether the goals of sociobiology, given the violation of its fundamental postulate by contemporary human societies, might not be better thought of as applied rather than descriptive, with respect to these societies. A proper answer to this question begins with the measurement of the pace and direction of natural selection within modern human populations, as compared to other sources of change. The vast preponderance of the shifts in human trait distributions, including the IQ distribution, appears to be due to environmental rather than genetic change. However, there remains the question of just how elastic these distributions are in the absence of reinforcing genetic change. (shrink)

Hybrid metaethical theories attempt to incorporate essential elements of expressivism and cognitivism, and thereby to accrue the benefits of both. Hybrid theories are often defended in part by appeals to slurs and other pejoratives, which have both expressive and cognitivist features. This paper takes far more seriously the analogy between pejoratives and moral predicates. It explains how pejoratives work, identifies the features that allow pejoratives to do that work, and models a theory of moral predicates on those features. The result (...) is an expressivist theory that, among other advantages, is immune to embedding difficulties and avoids an overlooked difficulty concerning attitude ascriptions that is lethal to most other hybrid theories. (shrink)

In _The Smile of Tragedy_, Daniel Ahern examines Nietzsche’s attitude toward what he called “the tragic age of the Greeks,” showing it to be the foundation not only for his attack upon the birth of philosophy during the Socratic era but also for his overall critique of Western culture. Through an interpretation of “Dionysian pessimism,” Ahern clarifies the ways in which Nietzsche sees ethics and aesthetics as inseparable and how their theoretical separation is at the root of Western nihilism. (...) Ahern explains why Nietzsche, in creating this precursor to a new aesthetics, rejects Aristotle’s medicinal interpretation of tragic art and concentrates on Apollinian cruelty as a form of intoxication without which there can be no art. Ahern shows that Nietzsche saw the human body as the vessel through which virtue and art are possible, as the path to an interpretation of “selflessness,” as the means to determining an order of rank among human beings, and as the site where ethics and aesthetics coincide. (shrink)

This book excavates the political thought embedded in Heidegger’s philosophy. Though keenly aware of the controversy over Heidegger’s National Socialism, Ward highlights the political ramifications of Heidegger’s thought as opposed to entering the polarized debate concerning the “Heidegger Case.” Chapter 1 accesses Heidegger’s political thought via the distinction Heidegger made between science and philosophy. This leads to Heidegger’s view that modern “culture,” is basically “... superficial and merely contemporary. ‘Liberalism’ will be its political embodiment”. Chapter 2 pursues these themes with (...) special emphasis on Heidegger’s opposition to any naturalistic or biological interpretation of human beings, and this in contrast with the racism of National Socialism. The third chapter describes how, for Heidegger, the rank of a people can be determined in terms of how that people comes to terms with the question of Being. Those who have not fallen away from this question still stand at the highest rank, while those who have are spiralling into decline. As in chapter 2, Nietzsche looms large in this chapter, and one gets the distinct impression here that Heidegger has taken up the Nietzschean project of restoring an order of rank sans physiologie. In chapter 4, Ward articulates “the decisive difference between Heidegger’s National Socialism and that of the National Socialists themselves”. This difference is explored through Heidegger’s interpretation of work—both physical and intellectual—as a means to understanding Heidegger’s critique of Marxism, the role of the university, and, therewith, the primarily philosophical foundation of the sciences within the spiritual mission of the German people. (shrink)

Hybrid metaethical theories attempt to incorporate essential elements of expressivism and cognitivism, and thereby to accrue the benefits of both. Hybrid theories are often defended in part by appeals to slurs and other pejoratives, which have both expressive and cognitivist features. This paper takes far more seriously the analogy between pejoratives and moral predicates. It explains how pejoratives work, identifies the features that allow pejoratives to do that work, and models a theory of moral predicates on those features. The result (...) is an expressivist theory that, among other advantages, is immune to embedding difficulties and avoids an overlooked difficulty concerning attitude ascriptions that is lethal to most other hybrid theories. (shrink)

Ignorance is trending. Politicians boast, "I'm not a scientist." Angry citizens object to a proposed state motto because it is in Latin, and "This is America, not Mexico or Latin America." Lack of experience, not expertise, becomes a credential. Fake news and repeated falsehoods are accepted and shape firm belief. Ignorance about American government and history is so alarming that the ideal of an informed citizenry now seems quaint. Conspiracy theories and false knowledge thrive. This may be the Information Age, (...) but we do not seem to be well informed. In this book, philosopher Daniel DeNicola explores ignorance -- its abundance, its endurance, and its consequences. (shrink)

Corporate Strategy has emerged as a central metaphor for private-sector enterprise. Given inherent imperfections in markets, one important question to consider is how well the practice of Corporate Strategy contributes to social welfare. An account of the implicit morality of free markets is developed as a standard against which two particular, second best solutions to market imperfections — namely, American federal antitrust policy and Corporate Strategy — are compared. Corporate Strategy is subsequently evaluated in terms of the fundamental principles of (...) Rawls' theory of justice. In both analyses, Corporate Strategy is found to depart significantly and systematically from the standards of social justice. An alternative principle, grounded in the concept of duty, is introduced as a means for reconceptualizing Corporate Strategy. (shrink)

In all facets of our lives, humans construct meaning to understand their place in the world and their relationships to one another and to broader environments. Within this semantic web, words, stor...

George Herbert Mead has long been known for his social theory of meaning and the 'self' - an approach which becomes all the more relevant in light of the ways we develop and represent ourselves online. But recent scholarship has shown that Mead's pragmatic philosophy can help us understand a much wider range of contemporary issues including how humans and natural environments mutually influence one another, how deliberative democracy can and should work, how thinking is dependent upon the body and (...) on others, and how social changes in the present affect our understandings of the past. Historical scholarship has also changed what we know of Mead's life, including new emphasis on his social reform efforts, his engagement with colonization and war, and critical reinterpretation of the works published after his death. This book provides an approachable introduction to Mead's contemporary relevance in the social sciences, showing how a pragmatic view of social action serves as the core of Mead's theory, offering striking insights into human agency, symbolism, politics, social change, temporality, and materiality. As such, it will appeal to scholars of sociology and the social sciences more broadly, with interests in social theory and the enduring importance of the sociological classics. (shrink)

Kierkegaard’s distinction of chatter from silence gives forgiveness a linguistic spin. How can forgiveness be spoken? Is forgiveness something to be said and heard? Is saying it aloud saying too much, or too little? What is said when (and if) forgiveness is said? Should forgiveness be chatted away, or reserved in silence? For Kierkegaard, the answer(s) is (are) neither/nor: forgiveness can only be said indirectly, kept (almost) indistinguishable from resentment or indifference, as if discarded in the face of offense—if it (...) is to happen. (shrink)

A new proof of the impossibility of a universal quantum-classical dynamics is given. It has at least two consequences. The standard paradigm “quantum system is measured by a classical apparatus” is untenable, while a quantum matter can be consistently coupled only with a quantum gravity.

How important is atheism for Jewish history and Jews for the history of atheism? Modern Jewish histories have tended to focus on Jewish secularization rather than atheism, and historical surveys of atheism in the West have tended to neglect the Jewish experience which is subsumed in the Judeo-Christian tradition. It is possible to make the case that the secularization narrative privileges social change over Jewish intellectual engagement with non-belief, and that just as Jewish and Christian conceptions of theism differ, so (...) do their atheisms. Jewish historical attitudes towards atheism are complicated and have shifted over time. Here, skeptical tendencies, that is, attitudes and ideas that would be associated later with atheism, will be considered alongside claims about atheism per se. (shrink)

La imagen del jorobado que aparece aquí y allá en el corpus benjaminiano, una imagen que el mismo Benjamin califica como el prototipo de la distorsión es también el prototipo del sujeto necesitado de perdón. Una lectura crítica de los lugares en los que Benjamin refiere a esta “imagen distorsionada” ofrece la posibilidad de levantar una teoría del perdón que no reduce el perdón a una forma jurídica, a una particular dinámica emocional, o a un intercambio de condiciones morales, sino (...) que la dota además de una clara dimensión corporal que está simplemente ausente en la mayoría de las consideraciones a propósito del perdón desarrolladas en el siglo XX. (shrink)

Limited strikes are arguably different from war insofar as they are more circumscribed, less destructive, and cost less in blood and treasure to employ. However, what they can achieve is also considerably more circumscribed than what is set out by the goals of war. How do we morally evaluate limited strikes? As part of the roundtable, “The Ethics of Limited Strikes,” this essay argues that we need to turn to the ethics of limited of force, orjus ad vim, to do (...) so. Two moral assumptions that are the keystone tojus ad vimcan shed light on the moral imperatives and ethical dilemmas of undertaking limited strikes. First, such strikes should be seen as an alternative to war, and not part of thejus ad bellumlast resort process. What I call the “Rubicon assessment” determines at what level force should be used: at the level of war, with all its costs and unpredictability, or at that of the more predictable and less costly limited force. Second, limited strikes should adhere to a “presumption against escalation”; that is, a moral commitment not to escalate to war. This essay highlights these moral principles in five different limited strike scenarios: “hot pursuit,” “red line,” “the last straw,” “the point of no return,” and “the right of retaliation.” The conclusion explores the notion of justice after limited strikes, or what I calljus post vim, to show that while what can be accomplished by limited strikes is inherently constrained, they can, if used morally and in tune with diplomacy, be of service in the quest for peace. (shrink)

Deaths of Despair (DoD), or mortality resulting from suicide, drug overdose, and alcohol-related liver disease, have been rising steadily in the United States over the last several decades. In 2020, a record 186,763 annual despair-related deaths were documented, contributing to the longest sustained decline in US life expectancy since 1915–1918. This forum feature considers how health humanities disciplines might fruitfully engage with this era-defining public health catastrophe and help society better understand and respond to the crisis.

In short, he is known in a discipline in which he did not teach for a book he did not write. In Becoming Mead, Daniel R. Huebner traces the ways in which knowledge has been produced by and about the famed American philosopher.

_The Widening Scope of Shame_ is the first collection of papers on shame to appear in a decade and contains contributions from most of the major authors currently writing on this topic. It is not a sourcebook, but a comprehensive introduction to clinical and theoretical perspectives on shame that is intended to be read cover to cover. The panoramic scope of this multidisciplinary volume is evidenced by a variety of clinically and developmentally grounded chapters; by chapters explicating the theories of (...) Silvan Tomkins and Helen Block Lewis; and by chapters examining shame from the viewpoints of philosophy, social theory, and the study of family systems. A final section of brief chapters illuminates shame in relation to specific clinical problems and experiential contexts, including envy, attention deficit disorder, infertility, masochism, the medical setting, and religious experience. This collection will be of special interest to psychoanalytically oriented readers. It begins with a chapter charting the evolution of Freud's thinking on shame, followed by chapters providing contemporary perspectives on the role of shame in development, and the status of shame within the theory of narcissism. Of further psychoanalytic interest are two reprinted classics by Sidney Levin on shame and marital dysfunction. In both depth of clinical coverage and breadth of perspectives, _The Widening Scope of Shame_ is unique in the shame literature. Readable, well organized, and completely up to date, it becomes essential reading for all students of this intriguing and unsettling emotion and of human development more generally. (shrink)

Distinguished contributors take up eminent scholar Daniel R. Schwarz’s reading of modern fiction and poetry as mediating between human desire and human action. The essayists follow Schwarz’s advice, “always the text, always historicize,” thus making this book relevant to current debates about the relationships between literature, ethics, aesthetics, and historical contexts.

The papers by Mele, Randels, and Schrag call attention to the proper work that the concept of loyalty can perform. All threeauthors argue that loyalty is not taken seriously enough in modern corporations. As Mele, Randels, and Schrag independently ascribespecial status to the concept of loyalty, their analyses converge along numerous conceptual margins. Along these margins, a singularconception of loyalty comes into focus. Along these margins, we can see Simultaneously why each author assigns extraordinary status to loyalty and why, ironically, (...) each turns the special concept of loyalty over to the service of conventional management thinking. Mele,Randels, and Schrag leave it for us to ponder whether this ironic twist is unique to the concept of loyalty. (shrink)

Why has comedy become one of our most abiding ethical preoccupations as well as a dominant mode of political critique? It is suggested that comedy appeals to contemporary persons because it provides an apt social-aesthetic form through which to face up to living with others at a time when it is hard to bear others or otherness. The article outlines an ethics of modern individuality by developing a theory of comedy as more about building social bonds and finding out what (...) could be shared knowledge and experience than the toppling of dominant modes of thought or repudiating our mutuality with others. Drawing on Georg Simmel’s ‘The Law of the Individual’, the article develops a Simmelian reading of Freud’s Jokes to argue that comedy is one solution to resolving our mutual un-alikeness by way of forging knotted paths toward recognising how we could be alike. (shrink)

Integrating concepts of maintenance and of origins is essential to explaining biological diversity. The unified theory of evolution attempts to find a common theme linking production rules inherent in biological systems, explaining the origin of biological order as a manifestation of the flow of energy and the flow of information on various spatial and temporal scales, with the recognition that natural selection is an evolutionarily relevant process. Biological systems persist in space and time by transfor ming energy from one state (...) to another in a manner that generates structures which allows the system to continue to persist. Two classes of energetic transformations allow this; heat-generating transformations, resulting in a net loss of energy from the system, and conservative transformations, changing unusable energy into states that can be stored and used subsequently. All conservative transformations in biological systems are coupled with heat-generating transformations; hence, inherent biological production, or genealogical proesses, is positively entropic. There is a self-organizing phenomenology common to genealogical phenomena, which imparts an arrow of time to biological systems. Natural selection, which by itself is time-reversible, contributes to the organization of the self-organized genealogical trajectories. The interplay of genealogical (diversity-promoting) and selective (diversity-limiting) processes produces biological order to which the primary contribution is genealogical history. Dynamic changes occuring on times scales shorter than speciation rates are microevolutionary; those occuring on time scales longer than speciation rates are macroevolutionary. Macroevolutionary processes are neither redicible to, nor autonomous from, microevolutionary processes. (shrink)

Given the difficulty of characterizing the quandary introduced in Hume’s Appendix to the Treatise, coupled with the alleged “underdetermination” of the text, it is striking how few commentators have considered whether Hume addresses and/or redresses the problem after 1740—in the first Enquiry, for example. This is not only unfortunate, but ironic; for, in the Appendix, Hume mentions that more mature reasonings may reconcile whatever contradiction(s) he has in mind. I argue that Hume’s 1746 letter to Lord Kames foreshadows a subtle, (...) but significant, shift in Hume’s reasonings regarding the relevance of “real connexions”; that the Enquiry of 1748 provides evidence for this shift; and that this shift obviates Hume’s second thoughts by reconciling the contradiction that he had in mind. In short, Hume’s letter to Kames and Enquiry supply the retrodictive keys to a systematically satisfactory account. (shrink)

Epidemiology is a science of disease which specifies rates (illness prevalences, incidences, distributions, etc.). Evolution is a science of life which specifies changes (gene frequencies, generations, forms, function, etc.). Evolutionary Epidemiology is a synthesis of these two sciences which combines the empirical power of classical methods in genetical epidemiology with the interpretive capacities of neo-darwinian evolutionary genetics. In particular, prevalence rates of genetical diseases are important data points when reformulated for the purpose of analysis in terms of their evolutionary frequencies. (...) Traits which exceedprevalences beyond the rates of mutation (in Hardy-Weinberg calculations) or evidence unusualrange of phenotypic reaction are of special interest. This is because traits which did not confer advantages in the environment of evolutionary adaptation cannot accede, through natural selection, to anything but low rates of genomic prevalence.Evolutionary epidemiology is, in all of medicine, of particular promise in ongoing efforts to better understand psychopathology. Many complexities of phenotypic adjustment arise when new developmental demands are placed on an old genome. The new and complex biosocial ecology of human mass society now evokes different phenotypes than those in the prehistorical ecology to which the genome is structurally and functionally better adapted. Some of these new phenotypes are darwinian failures. In this paper, the theoretical implications of evolutionary epidemiology are extended and some tentative points of clinical application (particularly to psychiatry) are offered. (shrink)

I evaluate two claims; that (a) Jesus’ message as recorded in the gospels implies exclusivism with respect to salvation and that, correspondingly, (b) Christians should be exclusivists with respect to salvation. I evaluate these claims through a cataloguing and evaluation of the logical condition involved in each of the claims regarding conditions for salvation made by Jesus in the Gospel of John. As a result, I argue that (a) is false and that, correspondingly, so is (b).

The use of literature, and other sources from the humanities, in management education has become more prominent in recent years. But, there is reason to question the ethical justifications by which the marriage of Management and the Humanities is customarily defended. This paper is a critique of Management and the Humanities as it is practiced through the use of literature. By means of a liberal pragmatist kind of criticism, and a case analysis about a hypothetical Grand Theory of Management called (...) Theory R, I draw a sharp distinction between a Management and the Humanities approach that merely confirms conventional truths and a new approach to Management and the Humanities that enables students to grow as what Henry Giroux calls "critical rather than 'good' citizens." I show how this new approach can enable management educators to retrieve the potential of Management and the Humanities to contribute to liberal education. (shrink)

The use of literature, and other sources from the humanities, in management education has become more prominent in recent years. But, there is reason to question the ethical justifications by which the marriage of Management and the Humanities is customarily defended. This paper is a critique of Management and the Humanities as it is practiced through the use of literature. By means of a liberal pragmatist kind of criticism, and a case analysis about a hypothetical Grand Theory of Management called (...) Theory R, I draw a sharp distinction between a Management and the Humanities approach that merely confirms conventional truths and a new approach to Management and the Humanities that enables students to grow as what Henry Giroux calls "critical rather than 'good' citizens." I show how this new approach can enable management educators to retrieve the potential of Management and the Humanities to contribute to liberal education. (shrink)

This is the first modern book to describe Francis Bacon's jurisprudence. He has long been famous as a scientist, philosopher, politician and literary giant, but his career as one of England's greatest lawyers and jurists has been largely overlooked. Bacon's major contribution to Anglo-American jurisprudence is presented in such a way as to be suitable to specialists and non-specialists alike. The purpose is to restore Bacon to his rightful place as England's first true critical and analytical jurist, and to describe (...) how his legal thought related to his other great intellectual achievements. (shrink)