Patientenmobilität und grenzüberschreitende Gesundheitsversorgung sind alltägliche Phänomene in der Europäischen Union (EU). Im Jahr 2011 hat die EU eine Richtlinie erlassen, um in diesem Kontext Rechtssicherheit herzustellen. Bisher gibt es keine umfassenden systematischen Studien über ethische Aspekte grenzübergreifender Gesundheitsversorgung. In dieser Arbeit werden die rechtlichen Entwicklungen der grenzübergreifenden Gesundheitsversorgung dargestellt und die in der Literatur vereinzelt erwähnten ethisch relevanten Aspekte heuristisch und auf Patiententypologien aufbauend systematisch inventarisiert und diskutiert. Es zeigt sich, dass die Möglichkeit der Patientenmobilität und die damit vor (...) allem verbundenen Finanzierungsregelungen die Autonomie einiger Patienten sicherlich verbessern kann. Allerdings können wohl nicht alle Patienten Versorgungsverbesserungen erwarten. Im Gegenteil können sogar negative Konsequenzen für einige Patienten folgen, was vor allem aus gerechtigkeitstheoretischen Überlegungen kritisch zu sehen ist. (shrink)

ZusammenfassungPatientenmobilität und grenzüberschreitende Gesundheitsversorgung sind alltägliche Phänomene in der Europäischen Union. Im Jahr 2011 hat die EU eine Richtlinie erlassen, um in diesem Kontext Rechtssicherheit herzustellen. Bisher gibt es keine umfassenden systematischen Studien über ethische Aspekte grenzübergreifender Gesundheitsversorgung. In dieser Arbeit werden die rechtlichen Entwicklungen der grenzübergreifenden Gesundheitsversorgung dargestellt und die in der Literatur vereinzelt erwähnten ethisch relevanten Aspekte heuristisch und auf Patiententypologien aufbauend systematisch inventarisiert und diskutiert. Es zeigt sich, dass die Möglichkeit der Patientenmobilität und die damit vor allem (...) verbundenen Finanzierungsregelungen die Autonomie einiger Patienten sicherlich verbessern kann. Allerdings können wohl nicht alle Patienten Versorgungsverbesserungen erwarten. Im Gegenteil können sogar negative Konsequenzen für einige Patienten folgen, was vor allem aus gerechtigkeitstheoretischen Überlegungen kritisch zu sehen ist. (shrink)

Since its original publication in 1975, this groundbreaking work has awakened millions of concerned men and women to the shocking abuse of animals everywhere--inspiring a worldwide movement to eliminate much of the cruel and unnecessary laboratory animal experimentation of years past. In this newly revised and expanded edition, author Peter Singer exposes the chilling realities of today's "factory farms" and product-testing procedures--offering sound, humane solutions to what has become a profound environmental and social as well as moral issue. An (...) important and persuasive appeal to conscience, fairness, decency and justice, Animal Liberation is essential reading for the supporter and the skeptic alike.--From publisher description. (shrink)

The relationship of part to whole is one of the most fundamental there is; this is the first and only full-length study of this concept. This book shows that mereology, the formal theory of part and whole, is essential to ontology. Peter Simons surveys and criticizes previous theories, especially the standard extensional view, and proposes a more adequate account which encompasses both temporal and modal considerations in detail. 'Parts could easily be the standard book on mereology for the next (...) twenty or thirty years.' Timothy Williamson, Grazer Philosophische Studien. (shrink)

Acting Now to End World Poverty Peter Singer. were our own, and we cannot deny that the suffering and death are bad. The second premise is also very difficult to reject, because it leaves us some wiggle room when it comes to situations in.

According to standard teleosemantics, intentional states are selectional states. This claim is put forward not as a conceptual analysis, but as a ‘theoretical reduction’—an a posteriori hypothesis analogous to ‘water = H2O’. Critics have tried to show that this meta-theoretical conception of teleosemantics leads to unacceptable consequences. In this paper, I argue that there is indeed a fundamental problem with the water/H2O analogy, as it is usually construed, and that teleosemanticists should therefore reject it. Fortunately, there exists a viable alternative (...) to the water/H2O model which avoids the fundamental problem, while explaining the a posteriori character of teleosemantics equally well. (shrink)

Africa is a religiously plural society with interaction between people of different religions and diverse value systems. The author, Professor of Comparative Religion in Uganda, describes and compares the position of traditional African religion, Christianity, Islam and Baha'i Faith on selected moral issues relevant to Africa today. His central argument is that in order to maintain their identity, African people must rediscover their ethical and moral heritage. He also argues that the new African ethical and moral systems must take into (...) account the ethics of Christianity, Islam and the Baha'i Faith without embracing the cultures of the societies where those religions originated. (shrink)

This article examines the relationship between compromise and fairness, and considers in particular why, if a fair outcome to a conflict is available, the conflict should still be subject to compromise. It sets out the defining features of compromise and explains how fair compromise differs from both principled and pragmatic compromise. The fairness relating to compromise can be of two types: procedural or end-state. It is the coherence of end-state fairness with compromise that proves the more puzzling case. We offer (...) reasons why people should be allowed to resolve conflicting or competing claims through compromise, even if compromise comes at the expense of end-state fairness, but we resist the suggestion that the primary rationale for compromise is to be found in non-ideal circumstances. (shrink)

The topic of personal identity has prompted some of the liveliest and most interesting debates in recent philosophy. In a fascinating new contribution to the discussion, Peter Unger presents a psychologically aimed, but physically based, account of our identity over time. While supporting the account, he explains why many influential contemporary philosophers have underrated the importance of physical continuity to our survival, casting a new light on the work of Lewis, Nagel, Nozick, Parfit, Perry, Shoemaker, and others. Deriving from (...) his discussion of our identity itself, Unger produces a novel but commonsensical theory of the relations between identity and some of our deepest concerns. In a conservative but flexible spirit, he explores the implications of his theory for questions of value and of the good life. (shrink)

The current research applied a mid-level evolutionary theory that has been successfully employed across numerous animal species—life history theory—in an attempt to understand the Dark Triad personality trait cluster (narcissism, psychopathy, and Machiavellianism). In Study 1 (N = 246), a measure of life history strategy was correlated with psychopathy, but unexpectedly with neither Machiavellianism nor narcissism. Study 2 (N = 321) replicated this overall pattern of results using longer, traditional measures of the Dark Triad traits and alternative, future-discounting indicators of (...) life history strategy (a smaller-sooner, larger-later monetary dilemma and self-reported risk-taking behaviors). Additional findings suggested two sources of shared variance across the Dark Triad traits: confidence in predicting future outcomes and openness to short-term mating. (shrink)

PROBEX (PROBabilities from EXemplars), a model of probabilistic inference and probability judgment based on generic knowledge is presented. Its properties are that: (a) it provides an exemplar model satisfying bounded rationality; (b) it is a “lazy” algorithm that presumes no pre‐computed abstractions; (c) it implements a hybrid‐representation, similarity‐graded probability. We investigate the ecological rationality of PROBEX and find that it compares favorably with Take‐The‐Best and multiple regression (Gigerenzer, Todd, & the ABC Research Group, 1999). PROBEX is fitted to the point (...) estimates, decisions, and probability assessments by human participants. The best fit is obtained for a version that weights frequency heavily and retrieves only two exemplars. It is proposed that PROBEX implements speed and frugality in a psychologically plausible way. (shrink)

Peter A Joy reviews Assessing Lawyer's Ethics: A Practitioner's Guide by Adrian Evans.

In this paper, we move toward offering psychological benchmarks to measure success in building increasingly humanlike robots. By psychological benchmarks we mean categories of interaction that capture conceptually fundamental aspects of human life, specified abstractly enough to resist their identity as a mere psychological instrument, but capable of being translated into testable empirical propositions. Nine possible benchmarks are considered: autonomy, imitation, intrinsic moral value, moral accountability, privacy, reciprocity, conventionality, creativity, and authenticity of relation. Finally, we discuss how getting the right (...) group of benchmarks in human–robot interaction will, in future years, help inform on the foundational question of what constitutes essential features of being human. (shrink)

Non-reductive physicalism is the view that mental events cause other events in virtue of their mental properties and that mental properties supervene on, without being identical to, physical properties. Jaegwon Kim has presented several much-discussed arguments against this view. But the much simpler causal closure argument, which purports to establish that every mental property is identical to a physical property, has received less attention than Kim’s arguments. This paper aims to show how a non-reductive physicalist should rebut the causal closure (...) argument. A crucial premise in the argument is a principle stating that the physical world is causally closed. It states, roughly, that every physical event has a physical sufficient cause. I argue that when the principle is formulated in this way, the causal closure argument is invalid. Less frequently, the causal closure principle is formulated in terms of a difference-making conception of causation so that it states that every physical effect has a physical difference-making cause. I argue that the principle, so formulated, is false and the causal closure argument unsound. Either way the argument lacks the apodeictic force to compel acceptance of its conclusion. (shrink)

Issues of religious toleration might be thought dead and advocacy of religious toleration a pointless exercise in preaching to the converted, at least in most contemporary European societies. This paper challenges that view. It does so principally by focusing on issues of religious accommodation as these arise in contemporary multi-faith societies. Drawing on the cases of exemption, Article 9 of the ECHR, and law governing indirect religious discrimination, it argues that issues and instances of accommodation are issues and instances of (...) toleration. Special attention is given to issues that arise when the claims of religious belief conflict with those of other legally protected characteristics, especially sexual orientation. The paper uses a concept of toleration appropriate to a liberal democratic political order—one that replaces the ‘vertical’ ruler-to-subject model of toleration that suited early modern monarchies with a ‘horizontal’ citizen-to-citizen model appropriate to a political order that aims to uphold an ideal of toleration rather than itself extend toleration to those whose lives it regulates. (shrink)

"Peter Iver Kaufman is admirably and ideally qualified to undertake this project of reading More on politics in the light of Augustine on politics. In vigorous, well-paced prose, he tackles an important and original subject." —_Marcia L. Colish, Frederick B. Artz Professor of History, emerita, Oberlin College_ _“Incorrectly Political_ will attract readers not only because it is written with the author's characteristic flair and liveliness, but also because of his established capacity to bridge centuries of Western thought and history. (...) Written at the dawn of the new century, this book acquires deep resonance from the events unfolding around the world, circumstances to which Augustine’s and More's complex thoughts on political possibility still speak. If ever a study of such hoary figures from the Christian past deserved the label 'timely,' it is surely this one.” —_Kevin Madigan, Harvard University Divinity School_ Augustine in the fourth and fifth centuries and Thomas More in the sixteenth were familiar with the deceits and illusions that enabled even the most vile rulers to shore up their dignity and that gave repressive regimes an inviolability of sorts. Both men knew the politics of their times, both were involved in politics, and both were at one time politically ambitious. Augustine needed and made good use of government's powers of coercion and damage control in his struggle against the Donatists. The clear advantages of political protection and correction preoccupied More in his battle against Martin Luther. Both later changed their minds and believed, finally, the political imagination, based as it is on a desire for power, always and inevitably leads to devastation and suffering. Peter Iver Kaufman explains how and why we have failed to appreciate Augustine's and More's profound political pessimism, reintroducing readers to two of the Christian tradition's most enigmatic yet influential figures. Each had been disturbed by the reach of his own political ambitions—as by those of contemporaries. Each knew that government was useful—yet always deceitful. And each wrote a classic—widely read to this day, Augustine's _City of God_ and More's _Utopia,_as well as abundant correspondence and polemical tracts to explain why government on earth might be used, though never meaningfully improved. (shrink)

This paper examines the ramifications of Hume's view of the relation of conceivability to metaphysical possibility. It argues that the limitations Hume places of the representations involved in moves to conceivability to metaphysical possibility preclude any straightforward argument against full-blooded causal realism in Hume from conceivability. Furthermore, our finding certain states of affairs conceivable when they are not metaphysically possible is perfectly compatible with the thrust of the causal realist position.

The place of moral innocence in politics is the central theme of Peter Johnson's subtle and original book.

The last several decades have produced a slew of important studies by Marxists of the logic of capital, as well as numerous explorations by postcolonial theorists of the narratives that structure racial and ethnic discrimination. Far too often, however, these two currents have assumed different or even opposed trajectories, making it all the harder to transcend one-sided class-reductionist analyses and equally one-sided affirmations of identity that bypass or ignore class. In light of the new reality produced by the deepening crisis (...) of neoliberalism and the looming disintegration of the political order that has defined global capitalism since the end of the Cold War, the time has come to revisit theoretical approaches that can help delineate the integrality of race, class and capitalism. (shrink)

It is widely assumed that candidates for free, undetermined choices must have objective probabilities prior to their performance. Indeed although this premise figures prominently in a widely discussed argument against libertarianism, few libertarians have called it into question. In this article, I will investigate whether libertarians ought to reject it. I will conclude that doing so should not be tempting to event-causal libertarians or most agent-causal ones, because the added costs outweigh the benefits.

In his highly regarded history of the rise of clinical trials in America, HarryMarks describes how their widespread adoption resulted largely fromthe efforts of ‘therapeutic reformers’ who sought to replace the individualexpertise of clinicians with the ‘science of controlled experiment’. Thetransition described by Marks resembles in many respects the transition fromthe ‘truth-to-nature’ objectivity of individual experts to a ‘mechanical’ formof objectivity portrayed by Daston and Galison. In particular,Marks details the passage from a regime of trust in expertise and experts to (...) aregime based on the mechanical generation of data, the elimination ofhuman judgement and the adoption of a ‘view from nowhere’ where individual and group idiosyncrasies are systematically suppressedthrough recourse to quantitative methods.[...]. (shrink)

ABSTRACT:In this paper we examine how ethical values contribute to national economic prosperity. We extend the concept of an ethical wealth of nations first introduced by Donaldson in which he proposed four categories of ethical values—fairer distribution of goods, better government, ingrained social cooperation, and inculcation of economic duties—that can drive economic performance, but only if citizens ascribe “intrinsic value” to them independent of their economic interests. Our analysis draws on institutional economics and sociology research to show that if ethical (...) values are to drive economic performance, they must also be supported by the institutional fabric of the nation. We embed an expanded set of ethical values in a set of democratic, free market and civil society institutions spanning three sectors of society—political, economic and cultural respectively. We conclude by discussing the implications of our institutional framework for moral education. (shrink)

The twelfth century philosopher-theologian Fakhr al-Dīn al-Rāzī is well known for his critique of Avicennan metaphysics. In this paper, I examine his critique of Avicenna's physics, and in particular his rejection of the Avicennan and Aristotelian theory of place as the inner boundary of a containing body. Instead, Fakhr al-Dīn defends a definition of place as self-subsisting extension, an idea explicitly rejected by Aristotle and Avicenna after him. Especially in his late work, theMaṭālib, Fakhr al-Dīn explores a number of important (...) philosophical issues with reference to this theory of place, including the principle that two indiscernible things must be identical and the idea that motion and rest are always relative.RésuméLe philosophe-théologien du XIIesiècle Fakhr al-Dīn al-Rāzī est bien connu pour sa critique de la métaphysique avicennienne. Nous examinons, dans cet article, sa critique de la physique d'Avicenne, et en particulier son rejet de la théorie avicennienne et aristotélicienne du lieu – lieu comme limite interne du corps englobant. Alternativement, Fakhr al-Dīn défend une théorie du lieu comme extension auto-subsistante, doctrine explicitement révoquée par Aristote et Avicenne à sa suite. En particulier dans son œuvre tardive, lesMaṭālib, Fakhr al-Dīn explore plusieurs questions philosophiques importantes en rapport avec cette théorie du lieu, dont: le principe voulant que deux choses indiscernables soient identiques, et l'idée selon laquelle mouvement et repos sont toujours relatifs. (shrink)

Although it is widely acknowledged that Foucault’s accounts of the concept of heterotopia remain briefly sketched and somewhat confusing, the notion has provoked many interpretations and applications across a range of disciplines. In particular, it has been coupled with different stages or processes of modernity and persistently linked to forms of resistance. This article re-examines Foucault’s concept through a close textual analysis. It contrasts heterotopia with Lefebvre’s conceptualization of heterotopy and wider formulations of utopia. Drawing on Foucault’s study of the (...) spaces of literature of Borges, and particularly Blanchot, the article argues that heterotopia refers to varied spatial and temporal disruptions that imaginatively interrogate and undermine certain formulations of utopia. It concludes by outlining how heterotopia contests the space in which we live. (shrink)

The full-text of this article is not available in ORA, but you may be able to access the article via the publisher copy link on this record page.

This volume collects a wealth of articles covering a range of topics of practical concern in the field of ethics, including active and passive euthanasia, abortion, organ transplants, capital punishment, the consequences of human actions, slavery, overpopulation, the separate spheres of men and women, animal rights, and game theory and the nuclear arms race. The contributors are Thomas Nagel, David Hume, James Rachels, Judith Jarvis Thomson, Michael Tooley, John Harris, John Stuart Mill, Louis Pascal, Jonathan Glover, Derek Parfit, R.M. Hare, (...) Janet Radcliffe Richards, Peter Singer, and Nicholas Measor. (shrink)

In The Philosophy of Manners Peter Johnson makes a compelling case for manners as a subject for investigation by modern moral philosophy. He examines manners as 'little virtues', explaining their distinctive conceptual characteristics and charting their intricate detail and relationships with each other. In demonstrating why manners are important to our mutual expectations, Johnson reveals a terrain which modern moral philosophy has left largely unmapped. Through a critical examination of the ethics of John Rawls and Alasdair MacIntyre, Johnson shows (...) how the nature of manners constitutes a philosophical problem both for liberalism and its critics. Taking the recent revival of virtue ethics as its broad starting point, The Philosophy of Manners discusses the 'little virtues' as they are treated in the Aristotelian and Kantian traditions of writing on ethics. Original features of the book include discussions of nameless virtues, the logical intricacy of the 'little virtues' which compose manners, and the nature of their orchestration by the more substantial virtues and moral concerns. The aim throughout is to give manners a philosophically defensible place in the moral life - a place which neither inflates nor understates their importance. --an examination of why manners are essential to moral literacy and an ethical society --the first work of its kind - no other ethical investigation concentrates on manners --relevant to the recent revival of interest in virtue ethics and any course in contemporary ethics --will provoke argument and disagreement. (shrink)

ABSTRACT In Germany, applied ethics is under attack from a diverse coalition of left‐wing organisations, disability groups, and some conservative defenders of a strict doctrine of the sanctity of human life. The attack has been pressed to the point of forcing the cancellation of conferences and disrupting lectures or classes so that they cannot take place. This essay describes the extent and nature of the attack, and makes a preliminary assessment of its significance.

Formal logic provides us with a powerful set of techniques for criticizing some arguments and showing others to be valid. These techniques are relevant to all of us with an interest in being skilful and accurate reasoners. In this highly accessible book, Peter Smith presents a guide to the fundamental aims and basic elements of formal logic. He introduces the reader to the languages of propositional and predicate logic, and then develops formal systems for evaluating arguments translated into these (...) languages, concentrating on the easily comprehensible 'tree' method. His discussion is richly illustrated with worked examples and exercises. A distinctive feature is that, alongside the formal work, there is illuminating philosophical commentary. This book will make an ideal text for a first logic course, and will provide a firm basis for further work in formal and philosophical logic. (shrink)

Generally we think it good to tolerate and to accord recognition. Yet both are complex phenomena and our teaching must acknowledge and cope with that complexity. We tolerate only what we object to, so our message to students cannot be simply, ‘promote the good and prevent the bad’. Much advocacy of toleration is not what it pretends to be. Nor is it entirely clear what sort of conduct should count as intolerant. Sometimes people are at fault for tolerating what they (...) should not, or for tolerating what they should find unexceptionable. So virtue does not always lie with toleration. Tolerance can also seem condescending; should we therefore replace it with recognition? But recognition may not be able to coexist with the disapproval that makes toleration necessary. However, not everything about toleration and recognition is controversial; there are fixed points from which students can grapple with the issues presented by both. (shrink)

How should we deal with social diversity if we conceive it as cultural diversity? Appeals to cultural relativism and to the collective good of diversity provide inadequate answers. Taking cultural diversity seriously requires that we respond to it fairly or justly and that, in turn, requires an approach that is impartial (or neutral) amongst cultures. Claims of impartiality are often thought peculiarly implausible when applied to cultural diversity, but an impartialist approach is in fact peculiarly appropriate to that form of (...) diversity. The issue is not whether we can be impartial, but whether we are ready to accept the implications of describing a diversity as ?cultural? and, if we are, what form our impartiality should take. Attempts to avoid claims of impartiality by dealing with diversity through deliberative processes are misguided since those processes must embody commitments to impartiality if their outcomes are to be just. (shrink)

This paper delves into the nature of intellectual property rights in aesthetic creations, particularly works of visual art and literary works. The discussion focuses on copyrights interests, but there are also implications for trademark and patent rights. The argument assumes a fairly conventional definition of "property," namely, the set of legal relations between the owner and all other persons relating to the use, enjoyment and disposition of a tangible thing. The problem with such a definition as applied to aesthetic creations (...) is that no ordinary tangible thing necessarily embodies a creation which can exist in multiple copies, so the paper takes the transcendent view that the tangible thing subject to legal relations is the entire terra firma or material universe being shaped in the image, sounds or words of the aesthetic creation. Therefore, the paradigm suggested for intellectual property is a monopoly on shaping the entire physical universe, thus the Worldmaking concept. It then follows that intellectual property in an aesthetic creation enables the owner to stop plagiarists from using any part of the material world to recreate in the audience the imaginative experiences first created by the protected work. (shrink)

Adults and infants display a robust ability to perceive the unity of a center-occluded object when the visible ends of the object undergo common motion (e.g. Kellman, P.J., Spelke, E.S., 1983. Perception of partly occluded objects in infancy. Cognitive Psychology 15, 483±524). Ecologically oriented accounts of this ability focus on the primacy of motion in the perception of segregated objects, but Gestalt theory suggests a broader possibility: observers may perceive object unity by detecting patterns of synchronous change, of which common (...) motion is a special case. We investigated this possibility with observations of adults and 4-month-old infants. Participants viewed a center-occluded object whose visible surfaces were either misaligned or aligned, stationary or moving, and unchanging or synchronously changing in color or bright- ness in various temporal patterns (e.g. ¯ashing). Both alignment and common motion con- tributed to adults' perception of object unity, but synchronous color changes did not. For infants, motion was an important determinant of object unity, but other synchronous changes and edge alignment were not. When a stationary object with aligned edges underwent syn- chronous changes in color or brightness, infants showed high levels of attention to the object, but their perception of its unity appeared to be indeterminate. An inherent preference for fast over slow ¯ash rates, and a novelty preference elicited by a change in rate, both indicated that infants detected the synchronous changes, although they failed to use them as information for object unity. These ®ndings favor ecologically oriented accounts of object perception in which surface motion plays a privileged role. Ó 1999 Elsevier Science B.V. All rights reserved. (shrink)

A recently published hypothesis on the nature of time by physicist Richard A. Muller seeks to provide an objective account of the present moment and the ‘flow’ of time. Muller also claims that his hypothesis makes testable predictions. It is shown that the predictions offered cannot be used to test Muller’s hypothesis, that the hypothesis does not rate scientific status, has a number of questionable metaphysical premises, and is merely a re-fashioning of the Growing Block theory of time.

While ancient civilizations worshipped strong, active emotions, modern societies have favored more peaceful attitudes, especially within the democratic process. We have largely forgotten the struggle to make use of _thymos_, the part of the soul that, following Plato, contains spirit, pride, and indignation. Rather, Christianity and psychoanalysis have promoted mutual understanding to overcome conflict. Through unique examples, Peter Sloterdijk, the preeminent posthumanist, argues exactly the opposite, showing how the history of Western civilization can be read as a suppression and (...) return of rage. By way of reinterpreting the _Iliad_, Alexandre Dumas's _Count of Monte Cristo_, and recent Islamic political riots in Paris, Sloterdijk proves the fallacy that rage is an emotion capable of control. Global terrorism and economic frustrations have rendered strong emotions visibly resurgent, and the consequences of violent outbursts will determine international relations for decades to come. To better respond to rage and its complexity, Sloterdijk daringly breaks with entrenched dogma and contructs a new theory for confronting conflict. His approach acknowledges and respects the proper place of rage and channels it into productive political struggle. (shrink)

Whistleblowing has been defined often and in differing ways in the literature. This paper has as its main purposes to clarify the meaning of whistleblowing and to speak for a narrow interpretation of it. A restrictive, general purpose definition is provided which contains six necessary elements: act of disclosure, actor, disclosure subject, target, disclosure recipient, and outcome.Whistleblowing is characterised as a dissenting act of public accusation against an organisation which necessitates being disloyal to that organisation. The definition differs from others (...) in many ways but especially by its emphasis on dissent, by being based on the ethical dilemma of conflicting loyalties, and by the strict way that dilemma is formulated in terms of confidentiality and proprietary rights over information. These features result in a definition in which motive has no part, and which requires a free choice decision to make disclosure to an external party. (shrink)

The discursive explosion that was provoked by the new genetics could support the impression that the ethical and social problems posed by the new genetics are somehow exceptional in their very nature. According to this view we are faced with special ethical and social problems that create a challenge so fundamental that the special label of genethics is needless to justify. The historical account regarding the evolution of the gene concepts could serve us to highlight the limits of what we (...) know about genes and what we can do with genes. The widespread notion about the exceptionality of genetic knowledge and its applicative possibilities is hardly justifiable and leads to misunderstandings regarding the conceptualization of the ethical and social problems we might face. Following a more realistic interpretation of the role of genes in human life we might avoid a whole set of fictive dilemmas and counterproductive regulatory efforts in bioethics. Bioethical discourse should move from the gene-centered scientific discourse toward the more sophisticated and complex discourses where human development represented as a matter of complex interactions between genomes and environments, between genes, educational factors, nutritional regimes, and other different developmental resources. If a gene is seen as one among the different developmental resources that are shaping a given human trait then both genethics and genetic exceptionalism could hardly be represented as a justified approach in discussing the ethical and social problems of genetics. (shrink)

The aim of this book is to provide a realist account of the constants in physics as an alternative to the prevailing conventionalist perspective of many philosophers. To do so the author first focuses on the discussion of the most primitive categories of physical constants which underlie modern science. Subsequently, the conventionalist case is examined in depth and, while held to be coherent, is shown to provide an incomplete account of how constants and related concepts of dimensions function in science. (...) Having repudiated the conventionalist challenge, the positive case for a realist account is then considered and is found to be comfortably accommodated by modest realist accounts such as the natural ontological attitude (NOA). (shrink)

The view that metaphysics is a waste of time appears to be gaining in popularity. It is held openly by many scientists and even many philosophers. I argue here that this is a consequence of the way metaphysics is usually done and the futility of a certain approach to it, and not a reason to suppose there is no useful knowledge to be acquired from its study. -/- .

I reply to each of the contributions in this issue. I agree with much that Hillel Steiner argues, especially his insistence that the associated ideas of impartiality and discontinuity are crucial to dealing satisfactorily with a diversity of competing claims. I am, however, less willing to conceive provision for that diversity as the role, rather than a role, that we should ascribe to rights. I question the success of David Miller’s endeavour to provide a unified justification of human rights grounded (...) in the concept of need. It is the notion of a minimally decent human life, rather than need itself, that does most of the justificatory work in Miller’s argument and, arguably, that notion does not deliver a genuinely unitary account of human rights. I concede the case for state funding of opera and the arts more generally to John Horton’s argument, but defend neutralism, and its associated distinction between the right and the good, as a strategy for dealing with diversity, including cultural diversity. I resist Richard Bellamy’s attempt to ground all basic rights in democracy and suggest that his argument relies upon idealized assumptions about the functioning of democracy. I share much of his objection to substituting judicial for political decision-making but argue that a strong moral commitment to rights need not imply a shift in power from democratic processes to courts. I endorse Albert Weale’s argument for favouring a beneficial design approach over a rights approach to healthcare and to many other social goods. Rights should not monopolize our moral and political thinking. (shrink)

We will analyse the representations and conceptualisation of genetics and genetic information in bioethical discourse. Genetics and genetic information is widely believed to be revolutionizing medicine and is sometimes misconceived as having a high predictive value compared to traditional diagnostics. We will attempt to present the inherent limitations of genetic information within its health care context. We␣will also argue against the exceptional treatment of genetic information that seems to govern bioethical reflection and regulatory approaches. And finally, we will make the (...) claim that geneticization should be seen as a more serious threat to our privacy, autonomy and freedom, than genetic discrimination. (shrink)

Immunofluorescent labelling demonstrates that human metaphase chromosomes contain hyperacetylated histone H4. With the exception of the inactive X chromosome in female cells, where the bulk of histone H4 is under‐acetylated, H4 hyperacetylation is non‐uniformly distributed along the chromosomes and clustered in cytologically resolvable chromatin domains that correspond, in general, with the R‐bands of conventional staining. The strongest immunolabelling is often found in T‐bands, the subset of intense R‐bands having the highest GC content. The majority of mapped genes also occurs in (...) R‐band regions, with the highest gene density in T‐bands. These observations are consistent with a model in which hyperacetylation of histone H4 marks the position of potentially active gene sequences on metaphase chromosomes. Since acetylation is maintained during mitosis, progeny cells receive an imprint of the histone H4 acetylation pattern that was present on the parental chromosomes before cell division. Histone acetylation could provide a mechanism for propagating cell memory, defined as the maintenance of committed states of gene expression through cell lineages. (shrink)