18 found
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  1.  37
    Informing materials: drugs as tools for exploring cancer mechanisms and pathways.Etienne Vignola-Gagné, Peter Keating & Alberto Cambrosio - 2017 - History and Philosophy of the Life Sciences 39 (2):10.
    This paper builds on previous work that investigated anticancer drugs as ‘informed materials’, i.e., substances that undergo an informational enrichment that situates them in a dense relational web of qualifications and measurements generated by clinical experiments and clinical trials. The paper analyzes the recent transformation of anticancer drugs from ‘informed’ to ‘informing material’. Briefly put: in the post-genomic era, anti-cancer drugs have become instruments for the production of new biological, pathological, and therapeutic insights into the underlying etiology and evolution of (...)
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  2.  25
    Too many numbers: Microarrays in clinical cancer research.Peter Keating & Alberto Cambrosio - 2012 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 43 (1):37-51.
    In his highly regarded history of the rise of clinical trials in America, HarryMarks describes how their widespread adoption resulted largely fromthe efforts of ‘therapeutic reformers’ who sought to replace the individualexpertise of clinicians with the ‘science of controlled experiment’. Thetransition described by Marks resembles in many respects the transition fromthe ‘truth-to-nature’ objectivity of individual experts to a ‘mechanical’ formof objectivity portrayed by Daston and Galison. In particular,Marks details the passage from a regime of trust in expertise and experts to (...)
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  3.  31
    Of lymphocytes and pixels: The techno-visual production of cell populations.Alberto Cambrosio & Peter Keating - 2000 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 31 (2):233-270.
  4.  16
    Patents and Free Scientific Information in Biotechnology: Making Monoclonal Antibodies Proprietary.Alberto Cambrosio, Peter Keating & Michael Mackenzie - 1990 - Science, Technology and Human Values 15 (1):65-83.
    There has been some concern m recent years that economic interests in the biotechnology area could, particularly through patenting, have a constricting influence on scientific research. Despite this concern, there have been no studies of this phenomenon beyond isolated cases. In this article we examine the evolution of the biomedical field of hybridoma/monoclonal antibody research with detailed examples of the three types of patent claims that have emerged there—basic claims, claims on application techniques, and claims on specific antibodies. We analyze (...)
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  5.  17
    “Triple negative breast cancer”: Translational research and the assembling of diseases in post-genomic medicine.Peter Keating, Alberto Cambrosio & Nicole C. Nelson - 2016 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 59:20-34.
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  6.  15
    Histology agnosticism: Infra-molecularizing disease?Jonah Campbell, Alberto Cambrosio & Mark Basik - 2024 - Studies in History and Philosophy of Science Part A 104 (C):14-22.
  7.  12
    A New Clinical Collective for French Cancer Genetics: A Heterogeneous Mapping Analysis.Alberto Cambrosio, Claire Julian-Reynier, Andrei Mogoutov & Pascale Bourret - 2006 - Science, Technology, and Human Values 31 (4):431-464.
    Collaborative forms of work such as extended networks, expert groups, and consortia increasingly structure biomedical activities. They are particularly prominent in the cancer field, where procedures such as multicenter clinical trials have been instrumental in establishing the specialty of oncology, and subfields such as cancer genetics, where bioclinical activities—for example, testing for breast and ovarian cancer genes and follow-up interventions—are predicated on the articulation of a number of tasks performed by new clinical collectives. In this article, we examine the founding (...)
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  8.  25
    Between fact and technique: The beginnings of hybridoma technology.Alberto Cambrosio & Peter Keating - 1992 - Journal of the History of Biology 25 (2):175-230.
    At several places in this paper we have made use of a well-known rhetorical device: an argument was made; a character —dubbed “fictional reader” — was then evoked who voiced some objections against that particular argument; and finally, we answered those objections, thus bringing to a close, at least temporarily, our argument. The use of this device raises a question: “How is the presence of the ‘fictional reader” to be understood?” Is it a “mere” rhetorical tool, or does this character (...)
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  9.  26
    Correcting the Blueprint of Life: An Historical Account of the Discovery of DNA Repair Mechanisms. Errol C. Friedberg.Alberto Cambrosio - 1999 - Isis 90 (4):844-845.
  10.  18
    Molecularizing Biology and Medicine: New Practices and Alliances, 1910s-1970s. Soraya de Chadarevian, Harmke Kamminga.Alberto Cambrosio - 1999 - Isis 90 (3):619-620.
  11.  17
    Storia d'Italia. Volume III: Scienza e tecnica nella cultura e nella societa dal Rinascimento ad oggiGianni Micheli.Alberto Cambrosio - 1982 - Isis 73 (2):281-282.
  12. Making Collaboration Networks Visible.Andrei Mogoutov, Alberto Cambrosio & Peter Keating - 2005 - In Bruno Latour & Peter Weibel (eds.), Making Things Public. MIT Press. pp. 342--45.
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  13.  22
    Correction to: Informing materials: drugs as tools for exploring cancer mechanisms and pathways.Etienne Vignola-Gagné, Peter Keating & Alberto Cambrosio - 2017 - History and Philosophy of the Life Sciences 40 (1):12.
    The original version of this article unfortunately contained a mistake. Three entries are incorrect in the reference list. The corrected references are given below.
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  14.  97
    (1 other version)"Ours Is an Engineering Approach": Flow Cytometry and the Constitution of Human T-Cell Subsets. [REVIEW]Peter Keating & Alberto Cambrosio - 1994 - Journal of the History of Biology 27 (3):449 - 479.
  15.  42
    Introduction: Immunology as a historical object. [REVIEW]Alberto Cambrosio, Peter Keating & Alfred I. Tauber - 1994 - Journal of the History of Biology 27 (3):375-378.
  16.  28
    (1 other version)Adriana Petryna. When Experiments Travel: Clinical Trials and the Global Search for Human Subjects. xii + 258 pp., bibl., index. Princeton, N.J./Oxford: Princeton University Press, 2009. $24.95. [REVIEW]Alberto Cambrosio - 2010 - Isis 101 (3):679-680.
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  17.  33
    Helpers and Suppressors: On Fictional Characters in Immunology. [REVIEW]Peter Keating & Alberto Cambrosio - 1997 - Journal of the History of Biology 30 (3):381 - 396.
  18.  23
    Introduction: Historiographic Issues. [REVIEW]Peter Keating, Miriam Balaban, Alberto Cambrosio & Alfred I. Tauber - 1997 - Journal of the History of Biology 30 (3):317-320.