Genome editing enables very accurate alterations to DNA. It promises profound and potentially disruptive changes in healthcare, agriculture, industry, and the environment. This paper presents a multidisciplinary analysis of the contemporary development of genome editing and the tension between continuity and change. It draws on the idea that actors involved in innovation are guided by “sociotechnical regimes” composed of practices, institutions, norms, and cultural beliefs. The analysis focuses on how genome editing is emerging in different domains and whether this marks (...) continuity or disruption of the established biotechnology regime. In conclusion, it will be argued that genome editing is best understood as a technology platform that is being powerfully shaped by this existing regime but is starting to disrupt the governance of biotechnology. In the longer term is it set to converge with other powerful technology platforms, which together will fundamentally transform the capacity to engineer life. (shrink)

By the 1840s and 1850s biogeographical theory had polarized into two opposing views — both of which had their origins in the sixteenth or seventeenth centuries. At issue in this polarization was the question of God's involvement with His creation. At one end of the spectrum were Sclater, Agassiz, Kirby, and others who saw a neatly designed world in which geographical distributions were planned and executed by the hand of God at creation. For most of these naturalists, organisms were created (...) en masse within the regions they now occupy. Disjunct distributions were proof to them that God had indeed created species in situ as many individuals. These naturalists hoped to reveal God's biogeographical plan by discovering His regions of creation. They had hoped to demonstrate a neatly devised set of regions of creation which might be applicable to all creatures, but in attempting to do so, they arrived at conflicting sets of delineations — thus helping to undermine their conceptions of nature in which design (both idealist and utilitarian) played an important part.93At the other end of the biogeographical spectrum were the theoretical ideas of Prichard and Lyell, who viewed a more remote God — one who allowed His creation to be shaped and modified by secondary laws. Lyell in particular wished to leave considerations of design aside, hoping to demonstrate that the shape of the present creation is due to natural laws. Prichard and Lyell saw God's role in the creation of species (and distributions) as being extremely limited. In fact, the regions of creation seen today are in actuality only natural artifacts produced by migrations and barriers. They saw distributions being in constant flux, as was the rest of nature.Those supporting the views of Prichard and Lyell spent a great deal of effort in attempting to remove a major obstacle in their paths — disjunct distributions. If disjunct distributions were indeed the products of separate creative acts, as Sclater and others claimed, then the arguments of Prichard and Lyell would be negated. For if the creation of a species was shown to be the product of multiple creations, then what was the need of migrations and dispersal mechanisms? Also at stake, of course, was the concept of species based upon generation. Darwin was well aware that if the supernatural implications of disjunct distributions could not be refuted, then his evolutionary system — founded upon a species concept based on descent — would be in peril.94A further barrier to the acceptance of the Prichard/Lyell view was the fact that those sympathetic to a nonsupernatural explanation of disjunct distributions could not agree upon a natural explanation for those anomalies, and an internal debate between naturalists within this group raged for decades.95By 1859 a biogeographical stalemate had occurred. Sclater and others, supporting their static view of nature, continued to look for regions of creation, pointing to disjunct distributions in support of their arguments, while those favorable to the views of Prichard and Lyell continued to search for natural explanations for such biogeographical anomalies.The key needed to resolve the biogeographical debate was a credible theory for species origins. By 1858 there were essentially three options for British naturalists: supernatural creation, Lamarckian transmutation, or natural creation. A few British naturalists grasped at these straws, but most workers preferred the option of remaining silent until a more viable explanation for the origin and distribution of species could be advanced.96 And not until the publication of Darwin's theory did that explanation become available. (shrink)

This study examines the form and function of gestural depictions that develop over extended stretches of concept explanation by a philosopher. Building onStreeck’s (2009)explorations of depiction by gesture, we examine how this speaker’s process of exposition involves sequences of multimodal, analogical depiction by which the philosophical concepts are not only expressed through gesture forms, but also dynamically analyzed and construed through gestural activity. Drawing on perspectives of gesture as active meaning making (Müller 2014,2016,Streeck 2009), we argue that the build-up of (...) gestures in depiction sequences, activated through a multimodal metaphor (Müller & Cienki 2009), engages the wider philosophical standpoint of the speaker. Using video analysis supported by interview data, we demonstrate how examination of gestures within and across discourse can lead to understanding of how dynamic, embodied, and subjective processes of conceptualization contribute to philosophical theorizing. (shrink)

Because youths are particularly vulnerable to social problems, philosophers since Plato to date have continued to show interest in developing, empowering, and protecting the youths. African youths are particularly far more than ordinarily vulnerable to various social problems including racism especially from outside the continent, mainly because of the shortfall in youth development and empowerment strategies in most African countries. Consequently, young people are pulled to countries with resources and infrastructures that provide them with opportunities to enlarge their capabilities and (...) improve their quality of life, where they are also faced with discriminatory, prejudicial, and antagonistic treatments simply because of their skin colour. So, one way to look at racism and reduce its effects is to examine those socio-political as well as economic structures that constitute obstacles to youth development and empowerment, and which push and expose the young in Africa to the ill-treatments emanating from racism. (shrink)

This paper offers a philosophical response to an aspect of the youth question in Africa – the question of youth vulnerability and its consequences on the human development outcome. To achieve the desired goal, first, I stretch the concept of pathogenic vulnerability from being more than ordinarily vulnerable to being far more than ordinarily vulnerable. Second, I identify two elements of African cultural structure – primacy of community over the individual and the belief that elders always possess superior knowledge over (...) the youth – that influence and restrict capacity/capabilities in African youth and therefore make their transition to adulthood defective. Consequently, the African youth is deprived of the special opportunity to develop, encounter and explore the various character options from which he/she learns, selects and forms her identity. Third, I argue that these restraints of capacity/capabilities make African youths far more than ordinarily vulnerable to human development outcome. (shrink)

L'article examine la relation de Bernard Lonergan à John Henry Newman, son premier inspirateur intellectuel. Il cherche à aller plus loin que les questions de références explicites ou des influences directes pour identifier les domaines majeurs òu les deux penseurs ont des affinités, ce qui inclut les limitations de la logique, l'attention aux structures cognitives, la centralité du jugement, la dialectique de l'autotranscendance que dévient des attitudes erronées, le parallèle entre l'assentiment réel et la conversion. Lonergan s'appropria et transforma les (...) fondements libérateurs qu'il découvrit au long de sa lecture de jeunesse de Newman. Un même ligne de pensée, empirique et psychologique, caractérise les deux auteurs, mais Lonergan va au delà des vastes catégories descriptives de Newman afin d'ouvrir des horizons plus larges à l'exploration de la méthode et de l'intériorité. (shrink)

Although both the ancient classical forms of tragedy and the nihilist tendencies of postmodern writing are marked by paralysis and passivity before fate, more religiously influenced periods of English literature are characterised by self-transcending and self-transforming movement beyond tragic impotence. This insight is illustrated briefly through references to Shakespeare's King Lear but it can also be found in Dante and in less explicitly Christian authors. The wisdom of humility exemplified in these literary masterpieces with a religious background embodies an implicit (...) theology of redemption, whereby evil can ultimately be transfigured into good. (shrink)

Though largely a theoretical endeavour, environmental ethics also has a practical agenda to help humans achieve environmental sustainability. Environmental ethicists have extensively debated the grounds, contents and implications of our moral obligations to nonhuman nature, offering up different notions of an 'environmental ethic' with the presumption that, if humans adopt such an environmental ethic, they will then engage in less environmentally damaging behaviours. We assess this presumption, drawing on psychological research to discuss whether or under what conditions an environmental ethic (...) might engender pro-environmental behaviour. We focus discussion on three lines of scholarship in the environmental ethics literature, on 1) intrinsic value, 2) care ethics, and 3) the land ethic. We conclude by commenting generally on both the limits and transformative potential of an environmental ethic in its larger sociocultural context. (shrink)

Though largely a theoretical endeavour, environmental ethics also has a practical agenda to help humans achieve environmental sustainability. Environmental ethicists have extensively debated the grounds, contents and implications of our moral obligations to nonhuman nature, offering up different notions of an 'environmental ethic' with the presumption that, if humans adopt such an environmental ethic, they will then engage in less environmentally damaging behaviours. We assess this presumption, drawing on psychological research to discuss whether or under what conditions an environmental ethic (...) might engender pro-environmental behaviour. We focus discussion on three lines of scholarship in the environmental ethics literature, on 1) intrinsic value, 2) care ethics, and 3) the land ethic. We conclude by commenting generally on both the limits and transformative potential of an environmental ethic in its larger sociocultural context. (shrink)

Although Alston believed epistemically circular arguments were able to justify their conclusions, he was also disquieted by them. We will argue that Alston was right to be disquieted. We explain Alston’s view of epistemic circularity, the considerations that led him to accept it, and the purposes he thought epistemically circular arguments could serve. We then build on some of Alston’s remarks and introduce further limits to the usefulness of such arguments and introduce a new problem that stems from those limits. (...) The upshot is that adopting Alston’s view that epistemically circular arguments can be used to justify their conclusions is more costly than even he thought. (shrink)

The ethical issues raised by cybersecurity practices and technologies are of critical importance. However, there is disagreement about what is the best ethical framework for understanding those issues. In this paper we seek to address this shortcoming through the introduction of a principlist ethical framework for cybersecurity that builds on existing work in adjacent fields of applied ethics, bioethics, and AI ethics. By redeploying the AI4People framework, we develop a domain-relevant specification of five ethical principles in cybersecurity: beneficence, non-maleficence, autonomy, (...) justice, and explicability. We then illustrate the advantages of this principlist framework by examining the ethical issues raised by four common cybersecurity contexts: penetration testing, distributed denial of service attacks (DDoS), ransomware, and system administration. These case analyses demonstrate the utility of this principlist framework as a basis for understanding cybersecurity ethics and for cultivating the ethical expertise and ethical sensitivity of cybersecurity professionals and other stakeholders. (shrink)

In an opinion piece penned at the Great War’s onset yet apparently unpublished until now, the historian of religion Hermann Gunkel outlined the opportunities he saw for the German people in anticipation of their triumph. He believed this war could consummate what the Napoleonic Wars and the Unification of Germany had not. Gunkel hoped for true German unity, more liberal domestic politics, and spiritual restoration. Further still, he referred to a resurgence of piety on account of the conflict. On the (...) Great War’s centenary, this documentation speaks to the mobilizing, nationalist activities of Gunkel in particular and of academicians and theologians more generally. (shrink)

The discussion of the recently derived quantum Hamilton equations for a spinning particle is extended to spin measurement in a Stern–Gerlach experiment. We show that this theory predicts a continuously changing orientation of the particles magnetic moment over the course of its motion across the Stern–Gerlach apparatus. The final measurement results agree with experiment and with predictions of the Pauli equation. Furthermore, the Einstein–Podolsky–Rosen–Bohm thought experiment is investigated, and the violation of Bells’s inequalities is reproduced within this stochastic mechanics approach. (...) The origin of the violation of Bell’s inequalities is traced to the the non-local nature of the velocity fields for an entangled state in the stochastic formalism, which is a result of a non-separable probability distribution of the considered particles. (shrink)

Tuberculosis (TB) is theTuberculosis (TB) second leading infectious cause of mortality worldwide and arguably the most important neglected topic in bioethics. This chapter: (1) explains the ethical importance of TB, (2) documents its neglect in bioethics discourse, (3) maps the terrain of ethical issues associated with TBTuberculosis (TB), and (4) advocates a moderate pluralistic approach to ethical issues associated with TB.

In their chapter, “In What Sense Does the One Exist? Existence and Hypostasis in Plotinus,” Paul DiRado and Michael Wiitala consider the problem of the One’s existence. Starting with the modern philosophical distinction between the “is” of predication and the “is” of existence, they show that Plotinus does not make such a distinction. The reason for this, they argue, is that Plotinus does not share with modern philosophers a univocal notion of existence. For Plotinus, both the verb “einai” (...) and the word “hypostasis” have variable meanings. Thus Plotinus can, in some contexts, say that “the One is” without being committed to the view that the One is or exists in the same way that other entities lower in the metaphysical hierarchy (Forms, say) exist. To say that “the One is” is to say that the One is the basis for the being of other entities; the Forms, on the other hand, truly “are,” in that they are the subjects of necessary and unchanging real predication. (shrink)

This volume draws together leading theologians and Christian ethicists from across the globe to critically engage with and reflect upon Gerald McKenny, widely acknowledged as one of the most original and important Christian ethicists working today. The essays highlight the significance of McKenny's interventions with a range of important debates in contemporary theological ethics, ranging from analyses of the Protestant conception of grace to bioethics and medicine. The Ethics of Grace is the first volume to facilitate critical engagements with a (...) number of key themes in McKenny's work, not in the least his interpretation of Karl Barth. Among the contributions, Jennifer Herdt discusses McKenny's Barthian interest in the relationship between nature and grace; Angela Carpenter uses his Barthian understanding of grace and human action as a framework to discuss Jonathan Edwards; Stanley Hauerwas pushes McKenny's theology beyond Barth. Economic, political, and technological themes are also discussed in depth, for instance in Robert Song's chapter on the phenomenology of biotechnological enhancement. Reaching far beyond the work of Gerald McKenny, this multifaceted volume is a high-level resource for students and scholars of theological and philosophical ethics. (shrink)

The race against COVID-19 has been intense and painful and many of us are now looking for a way to move on. We may try to seize a degree of comfort and security by convincing ourselves that we are among the “fittest”—that is, among those who have managed to survive—who can now hope for a “new-normal” time, relatively unscathed. But this isn’t what we should be hoping for. Our world, and ourselves, will never be free of COVID-19 or its insidious (...) effects. COVID-19, like climate change, is a threat multiplier and the challenges it has raised are now indelibly engraved in our vulnerable, interconnected lives. Rather than vainly hoping for a return to an imaginary, erstwhile “normal” what we need is something more fundamental: a new version of hope that embraces a courage to learn what we need to do, to enable us to live a future to which we aspire. Perhaps counter-intuitively, we need to accept that the COVID-19 experience has already changed us deeply and hope that we can learn from this and from the future changes that the pandemic will give rise to. We need to radicalize our responses to the challenges, enabling ourselves to learn new lessons about old but increasingly pertinent topics, such as the realities of human fragility, and inter-connection. (shrink)

Intellectual humility, which entails openness to other views and a willingness to listen and engage with them, is crucial for facilitating civil dialogue and progress in debate between opposing sides. In the present research, we tested whether intellectual humility can be reliably detected in discourse and experimentally increased by a prior self-affirmation task. Three-hundred and three participants took part in 116 audio and video-recorded group discussions. Blind to condition, linguists coded participants’ discourse to create an intellectual humility score. As expected, (...) the self-affirmation task increased the coded intellectual humility, as well as participants’ self-rated prosocial affect (e.g., empathy). Unexpectedly, the effect on prosocial affect did not mediate the link between experimental condition and intellectual humility in debate. Self-reported intellectual humility and other personality variables were uncorrelated with expert-coded intellectual humility. Implications of these findings for understanding the social psychological mechanisms underpinning intellectual humility are considered. (shrink)

Management theory and practice are facing unprecedented challenges. The lack of sustainability, the increasing inequity, and the continuous decline in societal trust pose a threat to ‘business as usual’. Capitalism is at a crossroad and scholars, practitioners, and policy makers are called to rethink business strategy in light of major external changes. In the following, we review an alternative view of human beings that is based on a renewed Darwinian theory developed by Lawrence and Nohria. We label this alternative view (...) ‘humanistic’ and draw distinctions to current ‘economistic’ conceptions. We then develop the consequences that this humanistic view has for business organizations, examining business strategy, governance structures, leadership forms, and organizational culture. Afterward, we outline the influences of humanism on management in the past and the present, and suggest options for humanism to shape the future of management. In this manner, we will contribute to the discussion of alternative management paradigms that help solve the current crises. (shrink)

Seit dem 2. nachchristlichen Jahrhundert werden die Schriften von Aristoteles kommentiert. Diese Ausgabe enthält griechische Kommentare zu seinem Werk vom 3. bis 8. Jahrhundert n. Chr., u. a. von Alexander von Aphrodiensias, Themistios, Joh. Philoponus, Simplicius in griechischer Sprache.

Michael A. Petersa and Fazal Rizvib aBeijing Normal University, Beijing, PR China; bMelbourne University, Melbourne, Australia Our minds are still racing back and forth, longing for a return to ‘no...

Attentional control theory (ACT) was proposed to account for trait anxiety’s effects on cognitive performance. According to ACT, impaired processing efficiency in high anxiety is mediated through inefficient executive processes that are needed for effective attentional control. Here we review the central assumptions and predictions of ACT within the context of more recent empirical evidence from neuroimaging studies. We then attempt to provide an account of ACT within a framework of the relevant cognitive processes and their associated neural mechanisms and (...) networks, particularly the fronto-parietal, cingular-opercula, and default mode networks. Future research directions, including whether a neuroscience-informed model of ACT can provide a platform for novel neurocognitive intervention for anxiety, are also discussed. (shrink)

ASHÉ: Ritual Poetics in African Diasporic is a collection of interdisciplinary essays contributed by international scholars and practitioners. Having distinguished themselves across such disciplines as Anthropology, Art, Music, Literature, Dance, Philosophy, Religion, and Theology and conjoined to construct a defining approach to the study of Aesthetics throughout the African Diaspora with the Humanities at the core, this collection of essays will break new ground in the study of Black Aesthetics. This book will be of great interest to scholars, practitioners, and (...) students interested in tracing African heritage identities throughout the African Diaspora through close examination of a variety of discourses directly connected to expressive elements of cultural production and religious rituals. (shrink)

ASHÉ: Ritual Poetics in African Diasporic is a collection of interdisciplinary essays contributed by international scholars and practitioners. Having distinguished themselves across such disciplines as Anthropology, Art, Music, Literature, Dance, Philosophy, Religion, and Theology and conjoined to construct a defining approach to the study of Aesthetics throughout the African Diaspora with the Humanities at the core, this collection of essays will break new ground in the study of Black Aesthetics. This book will be of great interest to scholars, practitioners, and (...) students interested in tracing African heritage identities throughout the African Diaspora through close examination of a variety of discourses directly connected to expressive elements of cultural production and religious rituals. (shrink)

Demands for absolute or near certainty are a common way for those with a political agenda to undermine science and to delay action. Through our combined experience in science, philosophy and cultural theory, we are acquainted with these attempts to undermine science. We want to help readers figure out how to evaluate their merits or lack thereof.

With this special volume of Speculations, the editors wanted to challenge the contested term "speculative realism," offering scholars who have some involvement with it a space to voice their opinions of the network of ideas commonly associated with the name.

In this third volume of Speculations, a serial imprint created to explore post-continental philosophy and speculative realism, a wide range of topics are covered, from the philosophy of religion to psychoanalysis to the philosophy of science to gender studies, and in a wide variety of formats (articles, interviews, position pieces, translations, and review essays).

Hermann Broch (1886-1951) gehört mit seinen Novellen, Dramen, Gedichten und vor allem mit seinen Romanen zu den bedeutendsten und innovativsten deutschsprachigen Autoren der ersten Hälfte des 20. Jahrhunderts. Sein Gesamtwerk, zu dem auch Tausende von Briefen gehören, umfasst nicht nur poetische Texte von Weltrang, sondern auch Schriften zur Literatur, zur Philosophie, zur Politik, zur Demokratie- und zur Massenwahntheorie. Das vorliegende Handbuch wurde in Kooperation mit einem internationalen Forscherteam realisiert. Es setzt sich zum Ziel, Brochs Biographie und sein gesamtes literarisches und (...) essayistisches Werk im Zeithorizont vorzustellen, in relevanten Kontexten zu analysieren und neu zu gewichten. Eigene Bearbeitung findet das epistolarische Werk des Autors, seine Kontakte und Netzwerke, darüber hinaus Stationen und Schwerpunkte der Broch-Rezeption. Mit einer umfangreichen, schwerpunktmäßig auf die letzten 25 Jahre konzentrierten Bibliographie zur Primär- und Forschungsliteratur wird der Band vervollständigt. (shrink)

We present an exactly soluble electron trajectory that permits an analysis of the soft (deep infrared) radiation emitted, the existence of which has been experimentally observed during beta decay via lowest order inner bremsstrahlung. Our treatment also predicts the time evolution and temperature of the emission, and possibly the spectrum, by analogy with the closely related phenomenon of the dynamic Casimir effect.

This collection of essays focuses on the work of James D. Marshall, who has been active in the philosophy of education for three decades. Deals with Marshall’s long-standing criticism of the public education system in New Zealand Discusses his work considering the relevance of Wittgenstein and Foucault for philosophy of education. Features tributes to Marshall in the form of interviews and testimonials. Contains remarks from Marshall himself in response to the commentaries of his colleagues.

Heyes’ book is an important contribution that rightly integrates cognitive development and cultural evolution. However, understanding the cultural evolution of cognitive gadgets requires a deeper appreciation of complexity, feedback, and self-organization than her book exhibits.

Drawing on insights from evolutionary psychology and modern neuroscience, this paper highlights propositions about human nature that have far reaching consequences, when applied to leadership. We specifically examine the main factors of human survival and extend them to a model for leadership in the twenty-first century. The discussion concludes with an outlook on the organizational and structural conditions that would allow for better and more balanced leadership.