This study aimed to explore stakeholders’ perspectives on the ethical considerations for returning individual pharmacogenomics research results to people living with HIV. A qualitative approach to investigation involved five focus group discussions with 30 Community representatives, 12 key informant interviews with researchers, and 12 in-depth interviews with research ethics committee members. In total, 54 stakeholders who were involved in pharmacogenomics research and HIV treatment and care contributed to the data collection between September 2021 and February 2022. The study explored five (...) prominent themes: (i) defining the nature of research results to return to participants; (ii) preparing research participants to receive their results; (iii) obtaining informed consent for the return of results; (iv) opinions on health personnel to return the results to participants; and (v) opinions on how research results should be communicated to participants. Respondents identified various strategies for the return of individual results with minimal ethical risks including the setting up of a diverse and independent committee to undertake a risk-benefit assessment based on local context; ongoing discussions about the possible kinds of results and their implications throughout the study; and employing genetic counsellors to communicate results to participants. The strategies identified in this study should be further studied and independently verified. (shrink)

Words refer to objects in the world, but this correspondence is not one-to-one: Each word has a range of referents that share features on some dimensions but differ on others. This property of language is called underspecification. Parts of the lexicon have characteristic patterns of underspecification; for example, artifact nouns tend to specify shape, but not color, whereas substance nouns specify material but not shape. These regularities in the lexicon enable learners to generalize new words appropriately. How does the lexicon (...) come to have these helpful regularities? We test the hypothesis that systematic backgrounding of some dimensions during learning and use causes language to gradually change, over repeated episodes of transmission, to produce a lexicon with strong patterns of underspecification across these less salient dimensions. This offers a cultural evolutionary mechanism linking individual word learning and generalization to the origin of regularities in the lexicon that help learners generalize words appropriately. (shrink)

The authors' aim is to provide a more complete picture of a non-anthropocentric relational ethics by addressing the failure to account for environmental justice. They argue that environmental ethics is always more than how discourses are layered over place, by situating moral agency through the body's affective repertoire of being-in-the-world. Empirical evidence for their argument is drawn from self-reflexive accounts of young Americans travelling to Ulu r u-Kata Tju t a National Park, Northern Territory, Australia as part of a study-group. (...) These reflexive travel narratives illustrate the dilemmas that even well-prepared visitors have in negotiating moral pathways invoked by the policy of reconciliation. (shrink)

Bioethicists who seek to defend commercial transactions that intuitively seem exploitative, such as organ sales and commercial surrogacy, typically pair a liberal analysis of exploitation with a libertarian analysis of autonomy. In this paper, I argue that the liberal analysis of exploitation, which focuses primarily on two party transactions between individuals, occludes the structural dimensions of exploitation. This occlusion then paves the way for the transaction to be understood in terms of libertarian autonomy. I propose that a vulnerability analysis paired (...) with a multidimensional and relational theory of autonomy highlights the structural dimensions of exploitation and exposes the myth-making that underlies claims that these forms of exploitation are autonomy-enhancing. (shrink)

In his recent book Reflective Democracy, Robert Goodin argues that 'external-collaborative' models of democratic deliberation procedures need to be supplemented by 'internal-reflective' deliberation. The exercise of the moral imagination plays a central role in Goodin's account of 'democratic deliberation within'. By imaginatively putting ourselves in the place of a range of others, he argues, including those who maybe not be able to represent their own interests, we can make their points of view 'communicatively present' in deliberation. Goodin's argument emphasizes the (...) role of art and other forms of cultural representation in helping to bring about this expansion of moral imagination. Drawing on debates in philosophy of mind concerning the scope and limits of our capacities to simulate other minds, I argue that Goodin's analysis of 'democratic deliberation within' conflates different kinds of imaginative project. In doing so, it underestimates both the difficulties of imaginatively putting ourselves in the place of others and the political risks in doing so. I argue, alternatively, that moral engagement with others involves the capacity for sympathy and that art and other forms of cultural representation can enlarge the scope of our sympathies, by assisting us to overcome imaginative resistance to alien points of view. In developing this argument, I provide a qualified defense of Iris Young's claim that respect for others involves 'asymmetrical reciprocity'. (shrink)

This article provides an account of some of the education provisions by Irish women religious, in the Anglophone world, in the nineteenth century. Although many orders sent Sisters around the globe, to both establish and run schools for English-speaking children, the main focus of this article is on two Irish orders, the Sisters of the Presentation of the Blessed Virgin Mary and the Sisters of Mercy. While the work of other female congregations is noted, the focus on these two orders (...) reflects the fact that they spread quickly around the globe, attracting many Irish vocations and eventually making a substantial contribution to education. The Sisters of Mercy were also known for their work in health care; however, the focus of this article is on education. The article commences with a review of the research in the field and the approaches taken by historians. The article also notes some lacunae in research and points to areas that merit more attention. The article then examines the experience of Irish nuns overseas and the contribution of the Mercy and Presentation nuns. (shrink)

The application of in vivo genetic lineage tracing has advanced our understanding of cellular mechanisms for tissue renewal in organs with slow turnover, like the lung. These studies have identified an adult stem cell with very different properties than classically understood ones that maintain continuously cycling tissues such as the intestine. A portrait has emerged of an ensemble of cellular programs that replenish the cells that line the gas exchange (alveolar) surface, enabling a response tailored to the extent of cell (...) loss. A capacity for differentiated cells to undergo direct lineage transitions allows for local restoration of proper cell balance at sites of injury. We present these recent findings as a paradigm for how a relatively quiescent tissue compartment can maintain homeostasis throughout a lifetime punctuated by injuries ranging from mild to life‐threatening, and discuss how dysfunction or insufficiency of alveolar repair programs produce serious health consequences like cancer and fibrosis. (shrink)

Concern for human vulnerability seems to be at the heart of bioethical inquiry, but the concept of vulnerability is under-theorized in the bioethical literature. The aim of this article is to show why bioethics needs an adequately theorized and nuanced conception of vulnerability. We first review approaches to vulnerability in research ethics and public health ethics, and show that the bioethical literature associates vulnerability with risk of harm and exploitation, and limited capacity for autonomy. We identify some of the challenges (...) emerging from this literature: in particular, how to reconcile universal human vulnerability with a context-sensitive analysis of specific kinds and sources of vulnerability; and how to reconcile obligations to protect vulnerable persons with obligations to respect autonomy. We then briefly survey some of the theoretical resources available within the philosophical literature to address these challenges, and to assist in understanding the conceptual connections between vulnerability and related concepts such as harm, exploitation, needs, and autonomy. We also sketch out a taxonomy of sources and kinds of vulnerability. Finally, we consider the implications for policy evaluation of making vulnerability an explicit and central focus of bioethics. Our investigation is in the form of a broad survey motivating a research agenda rather than a detailed analysis. (shrink)

This collection of original essays explores the social and relational dimensions of individual autonomy. Rejecting the feminist charge that autonomy is inherently masculinist, the contributors draw on feminist critiques of autonomy to challenge and enrich contemporary philosophical debates about agency, identity, and moral responsibility. The essays analyze the complex ways in which oppression can impair an agent's capacity for autonomy, and investigate connections, neglected by standard accounts, between autonomy and other aspects of the agent, including self-conception, self-worth, memory, and the (...) imagination. (shrink)

This enlightening study examines the relationship between being and God in Aristotle and Heidegger. Focusing on the methodology of each thinker, Catriona Hanley contrasts their beliefs on the infinite or finite nature of being, and on God’s role therein. The author also offers some indication of how modern thinkers might rethink the relation of the finite to the infinite, based on the work of these two philosophers. Being and God in Aristotle and Heidegger is a valuable book for philosophers (...) of religion. (shrink)

The concept of dignity plays a foundational role in the more recent versions of Martha Nussbaum’s capabilities theory. However, despite its centrality to her theory, Nussbaum’s conception of dignity remains under-theorised. In this paper we critically examine the role that dignity plays in Nussbaum’s theory by, first, developing an account of the concept of dignity and introducing a distinction between two types of dignity, status dignity and achievement dignity. Next, drawing on this account, we analyse Nussbaum’s conception of dignity and (...) contrast it with Kant’s conception of dignity. On the basis of this comparison between Nussbaum and Kant, we highlight tensions between Nussbaum’s Aristotelianism, which is central to her conception of dignity, and her commitment to political liberalism. This leads us to conclude that Nussbaum’s claim that her conception of dignity is only a partial political conception is implausible and that her conception of dignity seems to commit her to a satisficing form of perfectionist liberalism. (shrink)

In courses in the twenties and early thirties, Heidegger argues that in Aristotle the question of the being of beings (ontology) and that of the unity of beings (theology) are distinct. Although he treated the two questions as part of one science, prôtē philosophía, Aristotle did not, in Heidegger's view, discuss the way in which these questions belong together. Being is determined theoretically as presence; and God, the first mover, is an aítion, an explanatory ground of motion in sensible ousía. (...) God is required as a ground for the presence of beings as a whole. Heidegger no longer seeks explanatory grounds, nor does he prioritize theory. Rather, he inquires into the essence of ground, and the poietical involvement of Dasein in understanding being. The unity of Aristotle's questions is found in a groundless ground: Dasein as transcendence. The metaphysical god is thus no longer required in Heidegger's phenomenology. (shrink)

The ethical debate about neurotechnologies—including both drugs and implanted devices—has been largely framed around the questions of whether and when these technologies could damage or promote authenticity. Patients can experience changes in mood, behavior, emotion, or preferences—seemingly, changes in character or personality. Some describe such changes by saying they feel like different people; that they have become either more or less themselves; or that they feel as though some of their moods, behaviors, emotions or preferences are not their own. These (...) kinds of statements are used to describe both changes that a drug or device is... (shrink)

Why should we be tolerant? What does it mean to ‘live and let live’? What ought to be tolerated and what not? Catriona McKinnon presents a comprehensive, yet accessible introduction to toleration in her new book. Divided into two parts, the first clearly introduces and assesses the major theoretical accounts of toleration, examining it in light of challenges from scepticism, value pluralism and reasonableness. The second part applies the theories of toleration to contemporary debates such as female circumcision, French (...) Headscarves, artistic freedom, pornography and censorship, and holocaust denial. Drawing on the work of philosophers, such as Locke, Mill and Rawls, whose theories are central to toleration, the book provides a solid theoretical base to those who value toleration, whilst considering the challenges toleration faces in practice. It is the ideal starting point for those coming to the topic for the first time, as well as anyone interested in the challenges facing toleration today. (shrink)

The discussion of Heidegger's “destructive retrieve” of Aristotle has been intensified in recent years by the publication of Heidegger's courses in the years surrounding his magnum opus. Heidegger's explicit commentary on Aristotle in these courses permits one to read Being and Time with Aristotle's Nicomachean Ethics and Metaphysics. My paper analyzes a network of differences between the two thinkers, focusing on the relationship between theory and praxis. From Aristotle to Heidegger, there is: a shift from the priority of actuality to (...) the priority of possibility. This shift, I argue, is itself the metaphysical ground of: a shift from the priority of theory to the priority of praxis. This shift is seen most clearly in the way in which Heidegger's notion of Theorie is a modification of his poíesis. The temporal ground of the reversal is seen in Heidegger's notion of transcendence towards the world, and not towards an eternal being. (shrink)

Climate change creates unprecedented problems of intergenerational justice. What do members of the current generation owe to future generations in virtue of the contribution they are making to climate change? Providing important new insights within the theoretical framework of political liberalism, Climate Change and Future Justice presents arguments in three key areas: Mitigation: the current generation ought to adopt a strong precautionary principle in formulating climate change policy in order to minimise the risks of serious harm from climate change imposed (...) on future generations Adaptation: the current generation ought to create a fund to which members of future generations may apply for compensation if the risks of climate change harm imposed on them by the current generation ripen into harms Triage: future generations ought to keep alive hope for a return to the framework of justice for the social cooperation of future people less burdened by climate change harms. This work presents agenda-setting applications of important principles of democratic equality to the most serious set of political challenges ever faced by human society. It should be required reading for political theorists and environmental philosophers. (shrink)

The essays collected in this volume address a range of issues that arise when the focus of philosophical reflection on identity is shifted from metaphysical to practical and evaluative concerns. They also explore the usefulness of the notion of narrative for articulating and responding to these issues. The chapters, written by an outstanding roster of international scholars, address a range of complex philosophical issues concerning the relationship between practical and metaphysical identity, the embodied dimensions of the first-personal perspective, the kind (...) of reflexive agency involved in the self-constitution of one’s practical identity, the relationship between practical identity and normativity, and the temporal dimensions of identity and selfhood. In addressing these issues, contributors engage with debates in the literatures on personal identity, phenomenology, moral psychology, action theory, normative ethical theory, and feminist philosophy. (shrink)

This volume breaks new ground by investigating the ethics of vulnerability. Drawing on various ethical traditions, the contributors explore the nature of vulnerability, the responsibilities owed to the vulnerable, and by whom.

In this 2002 book, Anna Elisabetta Galeotti examines the most intractable problems which toleration encounters and argues that what is really at stake is not religious or moral disagreement but the unequal status of different social groups. Liberal theories of toleration fail to grasp this and consequently come up with normative solutions that are inadequate when confronted with controversial cases. Galeotti proposes, as an alternative, toleration as recognition, which addresses the problem of according equal respect to groups as well as (...) equal liberty to individuals. She offers an interpretation that is both a revision and an expansion of liberal theory, in which toleration constitutes an important component not only of a theory of justice, but also of the politics of identity. Her study will appeal to a wide range of readers in political philosophy, political theory, and law. (shrink)

This book brings together a group of international scholars, many of whom have already contributed to the debate on toleration, and who are offering fresh thoughts and approaches to it. The essays of this collection are written from a variety of perspectives: historical, analytical, normative, and legal. Yet, all authors share a concern with the sharpening of our understanding of the reasons for toleration as well as with making them relevant to the way in which we live with others in (...) our modern and diverse societies. (shrink)

From the paper's conclusion: "In conclusion, I have distinguished between two Rawlsian arguments for the SPP [strong precautionary principle] with respect to CCCs [climate change catastrophes]. Although both are persuasive, ultimately the “unbear-able strains” argument provides the most powerful categorical grounds for takingprecautionary action against CCCs. Overall, I have argued that the nature of CCCs requires us to take drastic precautions against further CC that could lead us to passthe tipping points that cause them. This is the case notwithstanding the (...) fact that weare in a state of strong uncertainty with respect to these events; indeed, our stronguncertainty with respect to them—given their nature—makes the case for action toprevent them even more persuasive, from the point of view of justice. Some peopletranslate the strong uncertainty of CCCs into weak uncertainty in order to justifytaking precautionary action using risk assessment.59My argument is complemen-tary to theirs. If divergent approaches to the uncertainty of CCCs neverthelessconverge on the PP, then we have what Cass Sunstein calls an “incompletelytheorized agreement” on a policy, that is, an agreement to which parties divided byoften deep theoretical differences can nevertheless give their assent,60which isall to the good from a political point of view. In the specific case of CC and itspossible catastrophes, the fact that such an agreement has emerged provides asliver of hope in the face of the increasingly dismal prospects for the planetuncovered by CC science as it progresses. At the level of principle, we are agreed,whatever justificatory reasons we advance. What is needed now—in the immedi-ate present—is policy to promote our principles, and the political will to enact it.". (shrink)

In the face of accelerating climate change and the parlous state of its politics, despair is tempting. This paper analyses two manifestations of despair about climate change related to (1) the inefficacy of personal emissions reductions, and (2) the inability to make a difference to climate change through personal emissions reductions. On the back of an analysis of despair as a loss of hope, the paper argues that the judgements grounding each form of despair are unsound. The paper concludes with (...) consideration of the instrumental value of hope in effective agency to tackle climate change. Overall, the paper’s assessment of personal despair about climate change as philosophically unjustified provides a fresh perspective on aspects of the debate about how to frame climate change in public debate. (shrink)

Wendy Rogers ist Professorin für klinische Ethik und Catriona Mackenzie ist Professorin für Philosophie. Beide lehren an der Macquarie University in Sydney, Australien. Susan Dodds ist Professorin für Philosophie an der La Trobe University in Melbourne, Australien. Alle drei befassen sich seit Jahren intensiv mit feministischer Theorie, angewandter und biomedizinischer Ethik sowie mit Moralphilosophie.

Recent decades have brought environmental justice studies to a much broader analysis and new areas of concern. We take this increased depth and breadth of environmental justice further by considering restorative justice, with a particular emphasis on reconciliation efforts between indigenous and non-indigenous citizens. Our focus is on the reconciliation efforts taken by the indigenous/non-indigenous jointmanagement structure of Uluṟu-Kata Tjuṯa National Park. Usinga framework of restorative justice within a bivalent environmental justice approach, we consider the current management policies at the (...) Park, particularly as it pertains to the controversial climb of the rock, Uluṟu. Our exploration of restorative environmental justice depends upon narrative analysis of embodied ecotourism affects in order to determine the capacity and obstacles of reconciliation efforts in the current management policy. Interviews with tourists from the Greater Sydney Metropolitan Area supply us with cases that provide affective experiences and a postcolonial narrative analysis of touring practices that we argue are imbued with nationalism and colonial naturalism that must be transformed in order to meet the requests of the Park’s traditional indigenous owners. We argue that restorative justice, within a bivalent environmental justice framework that already emphasizes other distributive and recognition measures, is vital for overcoming these obstacles for Australian environmental heritage. (shrink)

This paper examines the stage-level/individual-level hypothesis (Kratzer 1989; Diesing 1988) from the point of view of modern Scottish Gaelic. This language exhibits two syntactically distinct predicational structures, and in particular, two distinct subject positions distinguishable on the basis of word order. While the distinction between the two positions can be shown to support the stage/individual-level hypothesis in one sense, the picture is muddied by the fact that many habitual or ‘characteristic’ sentences seem to be formed according to the stage-level subject (...) construction type.The solution proposed relies on two novel elements. First, it distinguishes the classical Davisonian event variable from the Kratzerian one hypothesized to be the hallmark of the stage-level sentence type. And secondly, it makes a strict logical separation between two types of generics: generics proper, which involve quantifying over an individual variable; and habituals, which only involve quantification over an event variable. These are represented by two distinct logical types which may nevertheless give rise to similar truth conditions in context.I show that the analysis can be made to account for tense interpretation, the scope of genericity, and the facts of syntactic complementation in Scottish Gaelic. To the extent that the solution is successful, it is evidence for a quite direct mapping between syntactic and semantic representations and for the important intuitions behind the initial Kratzer/Diesing stage vs. individual-level hypothesis. (shrink)

Why should I let the toad work Squat on my life? Can’t I use my wit as a pitchfork And drive the brute off? Six days of the week it soils With its sickening poison — Just for paying a few bills! That's out of proportion. From Philip Larkin, ‘Toads’. ABSTRACT This paper mounts a Rawlsian argument for unconditional basic income on the grounds that it maximins the distribution of income and wealth understood as a social basis of self‐respect. The (...) most important objection to this argument available to Rawlsians is that basic income violates the demands of reciprocity, where reciprocity in any scheme of distribution is a requirement of justice. The second half of the paper addresses this objection. It is argued there that even if the objection can be made successfully by Rawlsians (and this is not clear), it is not sufficient to divest them of a commitment to basic income, given some practical considerations about the implementation of alternatives to basic income. (shrink)

Recent work on diachronic agency has challenged the predominantly structural or synchronic approach to agency that is characteristic of much of the literature in contemporary philosophical moral psychology. However, the embodied dimensions of diachronic agency continue to be neglected in the literature. This article draws on phenomenological perspectives on embodiment and narrative conceptions of the self to argue that diachronic agency and selfhood are anchored in embodiment. In doing so, the article also responds to Diana Meyers' recent work on corporeal (...) selfhood. (shrink)

In the Anthropocene, human beings are capable of bringing about globally catastrophic outcomes that could damage conditions for present and future human life on Earth in unprecedented ways. This paper argues that the scale and severity of these dangers justifies a new international criminal offence of ‘postericide’ that would protect present and future people against wrongfully created dangers of near extinction. Postericide is committed by intentional or reckless systematic conduct that is fit to bring about near human extinction. The paper (...) argues that a proper understanding of the moral imperatives embodied in international criminal law shows that it ought to be expanded to incorporate a new law of postericide. (shrink)

Contemporary liberal political justification is often accused of preaching to the converted: liberal principles are acceptable only to people already committed to liberal values. Catriona McKinnon addresses this important criticism by arguing that self-respect and its social conditions should be placed at the heart of the liberal approach to justification. A commitment to self-respect delivers a commitment to the liberal values of toleration and public reason, but self-respect itself is not an exclusively liberal value.

In the recent neuroethics literature, there has been vigorous debate concerning the ethical implications of the use of neurotechnologies that may alter a person’s identity. Much of this debate has been framed around the concept of authenticity. The argument of this chapter is that the ethics of authenticity, as applied to neurotechnological treatment or enhancement, is conceptually misleading. The notion of authenticity is ambiguous between two distinct and conflicting conceptions: self-discovery and self-creation. The self-discovery conception of authenticity is based on (...) a problematic conception of a static, real inner self. The notion of self-creation, although more plausible, blurs the distinction between identity and autonomy. Moreover, both conceptions are overly individualistic and fail sufficiently to account for the relational constitution of personal identity. The authors propose that a relational, narrative understanding of identity and autonomy can incorporate the more plausible aspects of both interpretations of authenticity, while providing a normatively more illuminating theoretical framework for approaching the question of whether and how neurotechnologies threaten identity. (shrink)

This volume brings together philosophical perspectives on emotions, imagination and moral reasoning with contributions from neuroscience, cognitive science, social psychology, personality theory, developmental psychology, and abnormal psychology. The book explores what we can learn about the role of emotions and imagination in moral reasoning from psychopathic adults in the general community, from young children, and adolescents with callous unemotional traits, and from normal child development. It discusses the implications for philosophical moral psychology of recent experimental work on moral reasoning in (...) the cognitive sciences and neurosciences. Conversely, it shows what cognitive scientists and neuroscientists have still to learn from philosophical perspectives on moral reasoning, moral reflection, and moral responsibility. Finally, it looks at whether experimental methods used for researching moral reasoning are consistent with the work in social psychology and with philosophical thought on adult moral reasoning in everyday life. The volume's wide-ranging perspectives reflect the varied audiences for the volume, from students of philosophy to psychologists working in cognition, social and personality psychology, developmental psychology, abnormal psychology, and cognitive neuroscience. (shrink)

I begin from the premise that “environmentalism needs queers.” Given that desire is a significant element in environmental ethics, and that the social organization of sexual-erotic desire has important impacts on human-nonhuman interactions, queer theory promises to aid environmental thought in unraveling and challenging some of these relations. I contribute the following elements to that challenge:the social-sexual organization of natural space; the organizing effects of dominant discourses of reproductive sexuality for both political possibility and bodily experience; and the retrieval (using (...) the works of queer theorist Elizabeth Grosz) of a queer/ecological “erotogenic ethics” based on the blurring of bodily boundaries through eroticized tactile apprehension of the (human and nonhuman) Other. (shrink)

This paper raises the issue of governmentality in popular environmental understandings of the (human) body. Understood as object-subjects of environmental management, “ecological bodies politic” are increasingly produced and organized by disciplinary discourses that have the (ironic) effect of reifying, enclosing and surveilling corporeal experiences in the world, especially for bodies deemed unruly. This paper thus deploys queer theories of corporeal materialization (Butler), and queer histories of corporeal-ecological abjection, toward a political account of embodiment oriented to creative opening and transgression, rather (...) than the increasingly hysterical bodily managerialism of pollution discourses. This paper also performs, through the transgressive presence of body narratives from dance experiences generated as part of a workshop on Japanese Butoh traditions, the kind of practiced body awareness suggested in the political account. (shrink)

This paper raises the issue of governmentality in popular environmental understandings of the (human) body. Understood as object-subjects of environmental management, “ecological bodies politic” are increasingly produced and organized by disciplinary discourses that have the (ironic) effect of reifying, enclosing and surveilling corporeal experiences in the world, especially for bodies deemed unruly. This paper thus deploys queer theories of corporeal materialization (Butler), and queer histories of corporeal-ecological abjection, toward a political account of embodiment oriented to creative opening and transgression, rather (...) than the increasingly hysterical bodily managerialism of pollution discourses. This paper also performs, through the transgressive presence of body narratives from dance experiences generated as part of a workshop on Japanese Butoh traditions, the kind of practiced body awareness suggested in the political account. (shrink)