The rise of neurotechnologies, especially in combination with artificial intelligence (AI)-based methods for brain data analytics, has given rise to concerns around the protection of mental privacy, mental integrity and cognitive liberty – often framed as “neurorights” in ethical, legal, and policy discussions. Several states are now looking at including neurorights into their constitutional legal frameworks, and international institutions and organizations, such as UNESCO and the Council of Europe, are taking an active interest in developing international policy and governance guidelines (...) on this issue. However, in many discussions of neurorights the philosophical assumptions, ethical frames of reference and legal interpretation are either not made explicit or conflict with each other. The aim of this multidisciplinary work is to provide conceptual, ethical, and legal foundations that allow for facilitating a common minimalist conceptual understanding of mental privacy, mental integrity, and cognitive liberty to facilitate scholarly, legal, and policy discussions. (shrink)

The increasing availability of brain data within and outside the biomedical field, combined with the application of artificial intelligence (AI) to brain data analysis, poses a challenge for ethics and governance. We identify distinctive ethical implications of brain data acquisition and processing, and outline a multi-level governance framework. This framework is aimed at maximizing the benefits of facilitated brain data collection and further processing for science and medicine whilst minimizing risks and preventing harmful use. The framework consists of four primary (...) areas of regulatory intervention: binding regulation, ethics and soft law, responsible innovation, and human rights. (shrink)

_BMC Medical Ethics_ is an open access journal publishing original peer-reviewed research articles in relation to the ethical aspects of biomedical research and clinical practice, including professional choices and conduct, medical technologies, healthcare systems and health policies. _BMC __Medical Ethics _is part of the _BMC_ series which publishes subject-specific journals focused on the needs of individual research communities across all areas of biology and medicine. We do not make editorial decisions on the basis of the interest of a study or (...) its likely impact. Studies must be scientifically valid; for research articles this includes a scientifically sound research question, the use of suitable methods and analysis, and following community-agreed standards relevant to the research field. Specific criteria for other article types can be found in the submission guidelines. _BMC series - open, inclusive and trusted_. (shrink)

Durch genomweite Analysen werden vielfältige gesundheitsrelevante Informationen über eine Person gewonnen. Solche Informationen können die Behandlung von Krankheiten verbessern. Sie ermöglichen aber auch Vorhersagen, ob eine Person und deren Verwandte in Zukunft möglicherweise erkranken werden. Der neuartige Charakter des Informationseingriffs und sein prädiktive Potential bedürfen der ethischen, juristischen und ökonomischen Reflexion, damit diese Technologie zum Wohl der Patienten, der Familienangehörigen und der Solidargemeinschaft eingesetzt werden kann. Die vorliegende Schrift leistet mit ihren interdisziplinären, vom BMBF finanzierten Analysen dazu einen Beitrag. Grundlagen (...) für einen ethisch und juristisch verantwortbaren Einsatz der Genomsequenzierung zu medizinischen Zwecken werden erörtert und Eckpunkte für Kostenanalysen sowie Elemente einer “Guten klinischen Praxis” präsentiert. (shrink)

En este texto examinaremos la relación problemática entre parrhesía, necropolítica y víctima. Nuestro trabajo estará radicado en una examinación de la necropolítica y su íntima relación con el biopoder foucaultiano, sus resistencias y efectos. Una resistencia particular está contenida en la noción de parrhesía, la cual recibirá su respectiva modificación modal ante los efectos de la necropolítica bajo las circunstancias examinadas. Con lo anterior, nuestra intención sería retratar una teoría de "víctimas y parrhesía" bajo el contexto de lo necropolítico y (...) la no–filosofía. Nos "serviremos" de la manera más ética posible de material visual, entablando unos respectivos límites teóricos. (shrink)

Rare Disease research has seen tremendous advancements over the last decades, with the development of new technologies, various global collaborative efforts and improved data sharing. To maximize the impact of and to further build on these developments, there is a need for model consent clauses for rare diseases research, in order to improve data interoperability, to meet the informational needs of participants, and to ensure proper ethical and legal use of data sources and participants’ overall protection. A global Task Force (...) was set up to develop model consent clauses specific to rare diseases research, that are comprehensive, harmonized, readily accessible, and internationally applicable, facilitating the recruitment and consent of rare disease research participants around the world. Existing consent forms and notices of consent were analyzed and classified under different consent themes, which were used as background to develop the model consent clauses. The IRDiRC-GA4GH MCC Task Force met in September 2018, to discuss and design model consent clauses. Based on analyzed consent forms, they listed generic core elements and designed the following rare disease research specific core elements; Rare Disease Research Introductory Clause, Familial Participation, Audio/Visual Imaging, Collecting, storing, sharing of rare disease data, Recontact for matching, Data Linkage, Return of Results to Family Members, Incapacity/Death, and Benefits. The model consent clauses presented in this article have been drafted to highlight consent elements that bear in mind the trends in rare disease research, while providing a tool to help foster harmonization and collaborative efforts. (shrink)

We explain the general significance of integer-based descriptors for natural shapes and show that the evolution of two such descriptors, called mechanical descriptors (the number _N_(_t_) of static balance points and the Morse–Smale graph associated with the scalar distance function measured from the center of mass) appear to capture (unlike classical geophysical shape descriptors) one of our most fundamental intuitions about natural abrasion: shapes get monotonically _simplified_ in this process. Thus mechanical descriptors help to establish a correlation between subjective and (...) objective descriptors of perceived objects. (shrink)

Plato claimed that the regular solids are the building blocks of all matter. His views, commonly referred to as the geometric atomistic model, had enormous impact on human thought despite the fact that four of the five Platonic solids can not fill space without gaps. In this paper we quantify these gaps, showing that the errors in Plato’s estimates were quite small. We also develop a mean field approximation to convex honeycombs using a generalized version of Plato’s idea. This approximation (...) not only admits to view convex mosaics in$$d=3$$d=3dimensions as a continuum but we also find that it is quite accurate, showing that Plato’s geometric intuition may have been remarkable. (shrink)

the Mona Lisa, the Mondscheinsonate, the Chanson d’automne are works of art, the salt shaker on your table, the car in your garage, or the pijamas on your bed are not. the basic question of the metaphysics of works of art is this: what makes a thing a work of art? that is: what sort of property do works of art have in virtue of which they are works of art? or more simply: what sort of property being a work (...) of art is? In this paper we argue that things are works of art in virtue of what they are like, their intrinsic features, that is, in virtue of the fact that they have the perceptual (auditory, visual, etc.) properties they have. In other words: being a work of art supervenes on perceptual-intrinsic features. Currently, this metaphysical view is extremely unpopular within the philosophy of art. It is unpopular because there allegedly exists a knock-down objection to it, the well-known argument from indiscernible counterparts. our thesis implies, among other things, that every perceptual duplicate of a work of art is also a work of art. according to the argument from indiscernible counterparts, however, there could be (or even: there are) indiscernible counterparts such that one of them is a work of art while the other is not. hence things cannot be works of art solely in virtue of what they are like. Our paper divides into three parts. In the first part we state our views. In the second part we defend it against various versions of the argument from indiscernible counterparts. (In doing so our position will become more plausible, we hope). In the final part we provide some meta-reflections on the matter. (shrink)

Based on the existence of polysemy (e.g., lunch can refer to both food and events), it is argued that central tenets of externalist semantics and Fodorian concept atomism, an externalist theory on which words lack semantic structure, are unsound. We evaluate the premise that these arguments rely on—that polysemous words have separate, finer‐grained senses. We survey the evidence across psychology and linguistics and argue that it shows that polysemy does not exist, at least not in this “sense”. The upshot is (...) that if polysemy does not exist, it cannot pose a problem for atomism or externalism. (shrink)

"In this book, Gabor Csepregi describes in detail the nature and scope of the body's innate abilities and reflects on their significance in human life."--BOOK JACKET.

SUMMARYThis study is centred on events in 1580 surrounding a scandalous publication of Machiavelli’s The Prince by Pietro Perna in Basel. With the presentation of new documents the paper fully reconstructs the judicial case that followed its publication, raising new questions about the author of the infamous book Vindiciae contra tyrannos. However, this fascinating story will serve only as a starting point for the investigation of Machiavelli's late-sixteenth-century reception, providing insights into not only the political and religious but also the (...) scientific context of its publication. These fields, it will be argued, were thoroughly interrelated, all sharing similar epistemological premises. (shrink)

ArgumentThe subject of the paper is the shift from an astrology-oriented astronomy towards an allegedly more objective, mathematically grounded approach to astronomy. This shift is illustrated through a close reading of Tycho Brahe's scientific development and the contemporaneous changes in his communicational strategies. Basing the argument on a substantial array of original sources it is claimed that the Danish astronomer developed a new astronomical discourse in pursuit of credibility, giving priority to observational astronomy and natural philosophical questions. The abandonment of (...) astrology in public discourse is primarily explained by Tycho's social position and greater sensibility to controversial issues. Tycho's example suggests that the changes in rhetorical strategies regarding astrology (which happened earlier than changes in astrological belief) should be given more recognition in the history of astronomy. (shrink)

If any nature of science perspective is to be incorporated in science-related curricula, it is hard to imagine a satisfactory didactic toolkit that neglects the social studies of science, the academic field of study of the institutional structures and networks of science. Knowledge production takes place in a world populated by actors, instruments, and ideas, and various epistemic cultures are responsible for providing the concepts, abstractions, and techniques that slowly trickle down the information pathways to become stabilized in university curricula (...) or ossified in high-school science, losing much of the tacit knowledge along the way that enabled the production of knowledge in the first place. The discussion of the sociology of science and the sociology of scientific knowledge is followed by a short overview of recent approaches in science studies and the studies of expertise. (shrink)

Recent work in social and cultural studies of science and technology has shown that the ‘epistemic dependence’ of laypeople on experts is not a relation of blind trust, but typically and necessarily involves critical assessment of expert testimonies. Normative epistemologists have suggested a number of criteria, mostly of contextual nature since expert knowledge means restricted cognitive access to some epistemic domain, according to which non-experts can reliably evaluate expert claims; while science studies scholars have concentrated on how laypeople can come (...) to warranted decisions about technical matters on non-technicalgrounds. Instead of addressing the problem transcendentally (how such decisions are possible) or normatively (how such decisions should be reached), this paper contrasts the recommendations available in the literature with the empirical findings of a rough case study concerning the public reaction to the H1N1 vaccine issue. Awareness of how lay people do come to such decisions may inform and refine normative philosophical investigations. (shrink)

ABSTRACTThis paper argues that Machiavelli's method, his inductive and comparative use of history and experience for political analysis, and his fashioning of historical-political analysis as ‘science’, played an important and still unrecognised role in his reception in the sixteenth century. It makes the case that Machiavelli's inductive reasoning and stress on historia and experientia offered a model for scientific method that open-minded sixteenth-century scholars, eager to understand, organise and augment human knowledge, could fit to their own epistemology. By focusing on (...) the question of method—a crucial issue for sixteenth-century contemporaries—the paper offers more than a key to the understanding of Machiavelli's positive reception. It also helps in apprehending the crucial importance of Lucretius to Machiavelli's scholarship; the role of the late Renaissance fascination with historia in his reception; and the breadth of appropriation of his method exactly in the decades when anti-Machiavellianism became official politics all over Europe. These claims are sustained through the cases of Machiavelli's early translators and promulgators; the French legal humanists and historiographers; the Swiss, Italian and French scholars engaging with medicine, Paracelsism and astronomy; the authors of political maxims from all over Europe; and finally Francis Bacon. (shrink)

This is a comprehensive study of the Derveni Papyrus. The papyrus, found in 1962 near Thessaloniki, is not only one of the oldest surviving Greek papyri but is also considered by scholars as a document of primary importance for a better understanding of the religious and philosophical developments in the fifth and fourth centuries BC. Gábor Betegh aims to reconstruct and systematically analyse the different strata of the text and their interrelation by exploring the archaeological context; the interpretation of (...) rituals in the first columns of the text; the Orphic poem commented on by the author of the papyrus; and the cosmological and theological doctrines which emerge from the Derveni author's exegesis of the poem. Betegh discusses the place of the text in the context of late Presocratic philosophy and offers an important preliminary edition of the text of the papyrus with critical apparatus and English translation. (shrink)

Continuity as appears to us immediately by intuition differs from its current formalization, the arithmetical continuum or equivalently the set of real numbers used in modern mathematical analysis. Motivated by the known mathematical and physical problems arising from this formalization of the continuum, our aim in this paper is twofold. Firstly, by interpreting Chaitin’s variant of Gödel’s first incompleteness theorem as an inherent uncertainty or fuzziness of the arithmetical continuum, a formal set-theoretic entropy is assigned to the arithmetical continuum. Secondly, (...) by analyzing Noether’s theorem on symmetries and conserved quantities, we argue that whenever the four dimensional space-time continuum containing a single, stationary, asymptotically flat black hole is modeled by the arithmetical continuum in the mathematical formulation of general relativity, the hidden set-theoretic entropy of this latter structure reveals itself as the entropy of the black hole, indicating that this apparently physical quantity might have a pure set-theoretic origin, too. (shrink)

SUMMARYThis paper presents the unusual story of the efforts of the political agent and pamphleteer Kaspar Schoppe to rehabilitate Machiavelli. Unlike the few earlier attempts by Machiavelli's Florentine descendants, Schoppe's campaign was motivated by complex factors, which were in a great part related to his vision of Catholic renewal. Through the story of Schoppe's campaign for Machiavelli, this paper offers not only a novel interpretation of this fascinating figure of the Counter-Reformation but also insight into the problems of science and (...) political philosophy in the Catholic world. (shrink)

George Molnar came to see that the solution to a number of the problems of contemporary philosophy lay in the development of an alternative to Hume's metaphysics. This alternative would have real causal powers at its centre. Molnar set about developing a thorough account of powers that might persuade those who remained, perhaps unknowingly, in the grip of Humean assumptions. He succeeded in producing something both highly focused and at the same time wide-ranging. He showed both that the notion of (...) a power was central and that it could serve to dispel a number of long-standing philosophical problems.Molnar's account of powers is as realist as any that has so far appeared. He shows that dispositions are as real as any other properties. Specifically, they do not depend for their existence on their manifestations. Nevertheless, they are directed towards such manifestations. Molnar thus appropriates the notion of intentionality, from Brentano, and argues that it is the essential characteristic of powers. He offers a persuasive case for there being some basic and ungrounded powers, thus ruling out the reducibility of the dispositional to the non-dispositional. However, he does allow that there are non-power properties as well as power properties. In this respect, his final position is dualistic.This is contemporary metaphysics of the highest quality. It is a work that was almost complete when its author died. It has been edited for publication by another specialist in the subject, Stephen Mumford, who has also provided an introduction that will allow non-specialists to become acquainted with the issues. David Armstrong, one of the greatest living metaphysicians and personal friend of George Molnar, has provided a Foreword. (shrink)

The short treatise known as Περὶ κόσμου is a learned piece of protreptic addressed to Alexander, ‘the best of princes’, usually identified with Alexander the Great. The treatise is traditionally attributed to Aristotle, and although it does espouse recognizably Aristotelian views, it contains various doctrinal and linguistic elements which have led the large majority of scholars to regard it as inauthentic. The dating of the treatise is a more controversial matter, though most scholars would put it somewhere in the Hellenistic (...) period. (shrink)

The new star of 1572 and the comet of 1577 had a major impact on the ways in which astronomical research developed in the late sixteenth and early seventeenth centuries. Behind this gradual but significant change there was an extended epistemological reform which placed increasing emphasis on reason and experience and strove to exclude arguments from Scripture and authority from scientific debate. This paper argues that the humanist debate on astrology after 1577, which was initiated by highly prestigious members of (...) a supraconfessional Republic of Letters, can be seen as an element of this process. Unlike earlier detractors of astrology, these new critics chiefly employed philosophical and scientific arguments concerning the legitimation of the entire art. By analysing a variety of accounts, this paper will reveal how great and complex the stakes in the debate over astrology were. They concerned not only the crucial problem of predestination and God’s interventionalism (hence also the possibility of miracles), but also the idea of science, the concept of the human mind, and ultimately the humanist ideal of the virtuous, rational, and responsible citizen. (shrink)

We are easily misguided as to the true nature of Facebook, and tend to treat it simply as a powerful technological instrument in the service of human intentions. We can, however, gain a better picture of it through recourse to the Jewish tradition of the golem, an image of human beings, created by them in a re‐enactment of their own creation by God. It turns into a magic servant in modernity with an inherent dynamic running between its human and its (...) subhuman characteristics. This dynamic is the main cause behind its becoming uncontrollable. In like manner, what is subhuman in Facebook serves its masters and functions under their total control, but also empowers Facebook's increasingly human operation, an algorithm‐based capability which raises growing doubts about what counts as human. Facebook implies the crisis of humanity which coincides with the “death of God,” that is, the obsolescence of the idea of a divine creator. (shrink)

The paper first discusses the metaphysical framework that allows the soul's integration into the physical world. A close examination of B36, supported by the comparative evidence of some other early theories of the soul, suggests that the word psuchê could function as both a mass term and a count noun for Heraclitus. There is a stuff in the world, alongside other physical elements, that manifests mental functions. Humans, and possibly other beings, show mental functions in so far as they have (...) a portion of that stuff. Turning to the physical characterization of the soul, the paper argues that B36 is entirely consistent with the ancient testimonies that say that psuchê for Heraclitus is exhalation. But exhalations cover all states of matter from the lowest moist part of atmospheric air to the fire of celestial bodies. If so, psuchê for Heraclitus is both air and fire. The fact that psuchê can manifest the whole range of physical properties along the dry-wet axis guarantees that souls can show different intellectual and ethical properties as well. Moreover, Sextus Empiricus, supported by some other sources, provides us with an answer how portions of soul stuff are individuated into individual souls. The paper closes with a brief discussion of the question whether, and if so with what qualifications, we can apply the term 'physicalism' to Presocratic theories of the soul. (shrink)

Here we investigate the classes RCA $^\uparrow_\alpha$ of representable directed cylindric algebras of dimension α introduced by Nemeti[12]. RCA $^\uparrow_\alpha$ can be seen in two different ways: first, as an algebraic counterpart of higher order logics and second, as a cylindric algebraic analogue of Quasi-Projective Relation Algebras. We will give a new, "purely cylindric algebraic" proof for the following theorems of Nemeti: (i) RCA $^\uparrow_\alpha$ is a finitely axiomatizable variety whenever α ≥ 3 is finite and (ii) one can obtain (...) a strong representation theorem for RCA $^\uparrow_\alpha$ if one chooses an appropriate (non-well-founded) set theory as foundation of mathematics. These results provide a purely cylindric algebraic solution for the Finitization Problem (in the sense of [11]) in some non-well-founded set theories. (shrink)

Current philosophical reflections on science have departed from mainstream history of science with respect to both methodology and conclusions. The article investigates how different approaches to reconstructing commitments can explain these differences and facilitate a mutual understanding and communication of these two perspectives on science. Translating the differences into problems pertaining to principles of charity, the paper offers a platform for clarification and resolution of the differences between the two perspectives. The outlined contextual approach occupies a middle ground between mainstream (...) history and sociology of science, bracketing questions of rationality, and individual coherence-maximizing, rationality-centered approaches. It can satisfy those, who believe that science is an epistemically privileged endeavor, and its epistemic content should not be neglected when reconstructing the scientists’ positions. It can also satisfy those who hold that it is naive to believe that the immediate context, e.g. the challenges to a theory, the expectations of the author about his audience, etc., does not affect the position a scientist takes. Its theoretical considerations are exemplified with a close study of the debate following the 1672 publication of Newton's theory of light and colours, also offering a novel reading of the development of his methodological views concerning the demonstrativity of the famous crucial experiment. Although we only show the capacity of the framework to analyze a direct controversy, given that it is hard to think about any scientific text as detached from an argumentative context, this approach has the potential to be a general guide for interpretation. (shrink)

The current confrontation between Russia and Ukraine raises essential problems regarding ethics and laws of war. It also presents an opportunity to compose an ethics case study to analyze the idea of a just war. The present-day war of Russia’s aggression toward Ukraine can hardly be analyzed ethically. We lean back to the seminal ideas of just war theorists to argue that war must be waged in a manner that is consistent with moral and ethical principles, such as proportionality, discrimination, (...) and respect for the rights of non-combatants. This article emphasizes the relationship between war and politics, and the belief that military forces should be used rationally and calculatedly. Wars have influenced the development of the modern world history. The fall of the Soviet Union led to 30 years of peace; however, the ideas of its creators returned to contemporary Russian thinking. We attempt to draw conclusions based on the past to enable conflict to end peacefully and a balance to be restored. (shrink)