Together, Models and Computability and its sister volume Sets and Proofs will provide readers with a comprehensive guide to the current state of mathematical logic. All the authors are leaders in their fields and are drawn from the invited speakers at 'Logic Colloquium '97' (the major international meeting of the Association of Symbolic Logic). It is expected that the breadth and timeliness of these two volumes will prove an invaluable and unique resource for specialists, post-graduate researchers, and the informed and (...) interested nonspecialist. (shrink)

Human control of action in routine situations involves a flexible interplay between (a) task-dependent serial ordering constraints; (b) top-down, or intentional, control processes; and (c) bottom-up, or environmentally triggered, affordances. In addition, the interaction between these influences is modulated by learning mechanisms that, over time, appear to reduce the need for top-down control processes while still allowing those processes to intervene at any point if necessary or if desired. We present a model of the acquisition and control of goal-directed (...) action that goes beyond existing models by operationalizing an interface between two putative systems—a routine and a non-routine system—thereby demonstrating how explicitly represented goals can interact with the emergent task representations that develop through learning in the routine system. The gradual emergence of task representations offers an explanation for the transfer of control with experience from the non-routine goal-based system to the routine system. At the same time it allows action selection to be sensitive both to environmental triggers and to biasing from multiple levels within the goal system. (shrink)

In this article, I compare and evaluate R. D. Laing and A. Esterson’s account of schizophrenia as developed in Sanity, Madness and the Family, social models of disability, and accounts of extended mental disorder. These accounts claim that some putative disorders should not be thought of as reflecting biological or psychological dysfunction within the afflicted individual, but instead as external problems. In this article, I consider the grounds on which such claims might be supported. I argue that problems should not (...) be located within an individual putative patient in cases where there is some acceptable test environment in which there is no problem. A number of cases where such an argument can show that there is no internal disorder are discussed. I argue, however, that Laing and Esterson’s argument—that schizophrenia is not within diagnosed patients—does not work. The problem with their argument is that they fail to show that the diagnosed women in their study function adequately in any environment. (shrink)

This paper is part of a broader project whose aim is to present a coherent unified approach to natural language dialogue semantics using tools from type theory. Here we explore aspects of our approach which relate to situation theory and situation semantics. We first point out a relationship between type theory and the Austinian notion of truth. We then consider how records in type theory might be used to represent situations and how dependent record types can be used to (...) class='Hi'>model constraints on situations. We then sketch treatments of attitude phenomena for which Barwise and Perry proposed situation semantic analyses (perception complements, belief, the Pierre puzzle) as well as two other intensional phenomena (intensional verbs and intentional identity). Finally we give a characterisation of the type theory used and a small illustrative fragment of English. (shrink)

Automatic imitation or “imitative compatibility” is thought to be mediated by the mirror neuron system and to be a laboratory model of the motor mimicry that occurs spontaneously in naturalistic social interaction. Imitative compatibility and spatial compatibility effects are known to depend on different stimulus dimensions—body movement topography and relative spatial position. However, it is not yet clear whether these two types of stimulus–response compatibility effect are mediated by the same or different cognitive processes. We present an interactive activation (...) model of imitative and spatial compatibility, based on a dual-route architecture, which substantiates the view they are mediated by processes of the same kind. The model, which is in many ways a standard application of the interactive activation approach, simulates all key results of a recent study by Catmur and Heyes (2011). Specifically, it captures the difference in the relative size of imitative and spatial compatibility effects; the lack of interaction when the imperative and irrelevant stimuli are presented simultaneously; the relative speed of responses in a quintile analysis when the imperative and irrelevant stimuli are presented simultaneously; and the different time courses of the compatibility effects when the imperative and irrelevant stimuli are presented asynchronously. (shrink)

Disney's animated film canon offers two contrasting visions of marriage and parenthood, which correspond to two rival portrayals of family life. The first vision of the family is what people can call the Irrational Matriarchy and Patriarchy (IMP) model. The second is what they can call the Family Unity Model. Disney's IMP families often recapitulate an old debate in political philosophy – that between Robert Filmer and John Locke. According to Locke, the most promising argument for the patriarchist (...) position is that parents give their children life and therefore have a power over their lives. In contrast with the Lockean vision of marriage, the author considers the marriage vows between Pongo and Perdita. In the Family Unity Model, having and rearing children is not to be feared as a threat to one's liberty, success, and happiness. Indeed, The Incredibles turns Beauvoir's critique of the family on its head in several ways. (shrink)

The Liberal Arts model of undergraduate education within small, internationally-focused University Colleges is becoming increasingly popular in Europe. This trend is most notable in the Netherlands, where the liberal arts model is acclaimed as filling a gap in Dutch undergraduate education at conventional research universities. This paper explores the status of the Dutch University College as simultaneously continuing the liberal arts tradition of the US, with its civic and pedagogic values, and providing a truly modern education preparing students (...) to find innovative and inter-disciplinary solutions to the complex problems which define contemporary society. It concludes that the traditional role of a liberal arts education in cultivating intellectual rather than vocation skills does not have to exclude its appeal as providing the skills necessary for professional success in global sectors of the 21 st century knowledge economy. (shrink)

The format of this book is unusual, especially for a book about linguistics. The book is meant primarily as a research monograph aimed at linguists who have some background in formal semantics, e. g. Montague Grammar. However, I have two other audiences in mind. Linguists who have little or no experience of formal semantics, but who have worked through a basic mathematics for linguists course (e. g. using Wall, 1972, or Partee, 1978), should, perhaps with the help of a sympathetic (...) Montague gramma rian, be able to discover enough of how I have adapted some of the basic ideas in formal semantics to make the developments that I undertake in the rest of the book accessible. Logicians and computer scientists who know about model theoretic semantics and formal systems should be able to glean enough from Chapters I and II about linguistic concerns and techniques to be able to read the remainder of the book, again possibly with the help of a sympathetic Montague grammarian. However, readers should beware. Chapter II is not meant as a general introduction either to formal semantics or to linguistics and while much of the presentation there is going over ground that is already well covered in the literature, the particular formulation and the emphases are very much oriented to the developments to be undertaken later in the book. (shrink)

As the prospects for a negotiated two-state solution to the Israeli–Palestinian conflict have dwindled, Jewish scholars in the United States have increasingly invoked the concept of diaspora to counter a purported Jewish consensus regarding Zionism. In this essay, I critique prominent exponents of this approach from a diasporic standpoint. My concern is not that Butler and the Boyarins attack Israel publicly, endorse a binational solution to the Israeli–Palestinian conflict, and/or support the movement for Boycott, Divestment, and Sanctions—rather, it is that (...) they lack a compelling vision for diasporic politics. Their visions prove wanting because they contest Zionism on the terrain of Jewish identity. To loosen Zionism’s hold, Butler and the Boyarins recover alternative approaches to the attainment or grounding of Jewish identity. Yet when framed as an ethic of particular identity, diasporic thinking can neither rebut Zionism’s political arguments, nor can it develop alternative models of Jewish self-rule. Instead of theorizing Jewish identity, I argue, diasporic thinkers should envision Jewish political solidarity beyond the confines of the nation-state. (shrink)

Background: Increasing interest in empirical ethics has enhanced understanding of healthcare professionals’ ethical problems and attendant decision-making. A four-stage decision-making model involving ethical attention, reasoning, intention and action offers further insights into how more than reasoning alone may contribute to decision-making.Aims: To explore how the four-stage model can increase understanding of decision-making in healthcare and describe the decision-making of an under-researched professional group.Methods: 23 purposively sampled UK community pharmacists were asked, in semi-structured interviews, to describe ethical problems in (...) their work and how they were resolved. Framework analysis of transcribed interviews utilised the four decision-making stages, together with constant comparative methods and deviant-case analysis.Results: Pharmacists were often inattentive and constructed problems in legal terms. Ethical reasoning was limited, but examples of appeals to consequences, the golden rule, religious faith and common-sense experience emerged. Ethical intention was compromised by frequent concern about legal prosecution. Ethical inaction was common, typified by pharmacists’ failure to report healthcare professionals’ bad practices, and ethical passivity emerged to describe these negative examples of the four decision-making stages. Pharmacists occasionally described more ethically active decision-making, but this often involved ethical uncertainty.Discussion: The four decision-making stages are a useful tool in considering how healthcare professionals try to resolve ethical problems in practice. They reveal processes often ignored in normative theories, and their recognition and the emergence of ethical passivity indicates the complexity of decision-making in practice. Ethical passivity may be deleterious to patients’ welfare, and concerns emerge about improving pharmacists’ ethical training and promoting ethical awareness and responsibility. (shrink)

This book is a sustained examination of issues in the philosophy of ecology that have been a source of controversy since the emergence of ecology as an explicit scientific discipline. The controversies revolve around the idea of a balance of nature, the possibility of general ecological knowledge and the role of model-building in ecology. The Science of the Struggle for Existence is also a detailed treatment of these issues that incorporates both a comprehensive investigation of the relevant ecological literature (...) and the development of an explicit theoretical framework in the philosophy of science. It addresses issues in the philosophy of ecology that are of particular importance for the deployment of ecology in the solution of environmental problems. It will have a cross-disciplinary appeal and will interest students and professionals in science, the philosophy of science, and environmental studies as well as policy-makers. (shrink)

This paper describes the application of eight statistical and machine-learning methods to derive computer models for predicting mortality of hospital patients with pneumonia from their findings at initial presentation. The eight models were each constructed based on 9847 patient cases and they were each evaluated on 4352 additional cases. The primary evaluation metric was the error in predicted survival as a function of the fraction of patients predicted to survive. This metric is useful in assessing a model’s potential to (...) assist a clinician in deciding whether to treat a given patient in the hospital or at home. We examined the error rates of the models when predicting that a given fraction of patients will survive. We examined survival fractions between 0.1 and 0.6. Over this range, each model’s predictive error rate was within 1% of the error rate of every other model. When predicting that approximately 30°K of the patients will survive, all the models have an error rate of less than 1.5%. The models are distinguished more by the number of variables and parameters that they contain than by their error rates; these differences suggest which models may be the most amenable to future implementation as paper-based guidelines. (shrink)

: This article seeks to explain how thought experiments work, and also the reasons why they can fail. It is divided into four sections. The first argues that thought experiments in philosophy and science should be treated together. The second examines existing accounts of thought experiments and shows why they are inadequate. The third proposes a better account of thought experiments. According to this account, a thought experimenter manipulates her worldview in accord with the “what if” questions posed by a (...) thought experiment. When all necessary manipulations are carried through, the result is either a consistent model or a contradiction. If a consistent model is achieved, the thought experimenter can conclude that the scenario is possible; if a consistent model cannot be constructed, then the scenario is not possible. The fourth section of the article uses this account to shed light on the circumstances in which thought experiments fail. (shrink)

Computability theory concerns information with a causal–typically algorithmic–structure. As such, it provides a schematic analysis of many naturally occurring situations. Emil Post was the first to focus on the close relationship between information, coded as real numbers, and its algorithmic infrastructure. Having characterised the close connection between the quantifier type of a real and the Turing jump operation, he looked for more subtle ways in which information entails a particular causal context. Specifically, he wanted to find simple relations on reals (...) which produced richness of local computability-theoretic structure. To this extent, he was not just interested in causal structure as an abstraction, but in the way in which this structure emerges in natural contexts. Post’s programme was the genesis of a more far reaching research project. In this article we will firstly review the history of Post’s programme, and look at two interesting developments of Post’s approach. The first of these developments concerns the extension of the core programme, initially restricted to the Turing structure of the computably enumerable sets of natural numbers, to the Ershov hierarchy of sets. The second looks at how new types of information coming from the recent growth of research into randomness, and the revealing of unexpected new computability-theoretic infrastructure. We will conclude by viewing Post’s programme from a more general perspective. We will look at how algorithmic structure does not just emerge mathematically from information, but how that emergent structure can model the emergence of very basic aspects of the real world. (shrink)

Recent controversy over the existence of biological laws raises questions about the cognitive aims of theoretical modeling in that science. If there are no laws for successful theoretical models to approximate, then what is it that successful theories do? One response is to regard theoretical models as tools. But this instrumental reading cannot accommodate the explanatory role that theories are supposed to play. Yet accommodating the explanatory function, as articulated by Brandon and Sober for example, seems to involve us once (...) again in a reliance on laws. The paper concludes that we must rethink both the nature of laws and theoretical explanation in biology. (shrink)

Focusing on the speculative methodologies used to generate models of the financial and meteorological future, this article develops a series of theses on the ‘evental’ and ‘atmospheric’ quality of contemporary power. What is at stake in the circulation of capital today, I argue, is not so much the exchange of equivalents as the universal transmutability of fluctutation. Whether we are dealing with the turbulence of world financial markets or that of complex earth systems, the non-dialectical relation can itself be extracted, (...) recombined and liquefied, as it were, in a dimension of its own. In the same way that financial derivatives price the variable relation between and across national currencies, weather derivatives now make it possible to issue contracts on the unknowable contingencies embedded in complex atmospheric relations. This reconfiguration of value requires a thorough rethinking of classical sociological conceptions of debt, promise and political violence. (shrink)

The Plant Ontology (PO; http://www.plantontology.org/) is a publicly-available, collaborative effort to develop and maintain a controlled, structured vocabulary (“ontology”) of terms to describe plant anatomy, morphology and the stages of plant development. The goals of the PO are to link (annotate) gene expression and phenotype data to plant structures and stages of plant development, using the data model adopted by the Gene Ontology. From its original design covering only rice, maize and Arabidopsis, the scope of the PO has been (...) expanded to include all green plants. The PO was the first multi-species anatomy ontology developed for the annotation of genes and phenotypes. Also, to our knowledge, it was one of the first biological ontologies that provides translations (via synonyms) in non-English languages such as Japanese and Spanish. There are about 2.2 million annotations linking PO terms to over 110,000 unique data objects representing genes or gene models, proteins, RNAs, germplasm and Quantitative Traits Loci (QTLs) from 22 plant species. In this paper, we focus on the plant anatomical entity branch of the PO, describing the organizing principles, resources available to users, and examples of how the PO is integrated into other plant genomics databases and web portals. We also provide two examples of comparative analyses, demonstrating how the ontology structure and PO-annotated data can be used to discover the patterns of expression of the LEAFY (LFY) and terpene synthase (TPS) gene homologs. (shrink)

There is a long history of controversy in ecology over the role of competition in determining patterns of distribution and abundance, and over the significance of the mathematical modeling of competitive interactions. This paper examines the controversy. Three kinds of considerations have been involved at one time or another during the history of this debate. There has been dispute about the kinds of regularities ecologists can expect to find, about the significance of evolutionary considerations for ecological inquiry, and about the (...) empirical credentials of theoretical studies of competition. Each of these elements is examined with an eye toward gaining philosophical clarification of the issues involved. In the process, certain shortcomings of contemporary philosophical theories are revealed. In particular, I argue that plausibility arguments based on background considerations are an important part of the model building tradition, but that current accounts of the structure and evaluation of scientific theories do little to illuminate this side of theoretical ecology. (shrink)

The development of analogical reasoning has traditionally been understood in terms of theories of adult competence. This approach emphasizes structured representations and structure mapping. In contrast, we argue that by taking a developmental perspective, analogical reasoning can be viewed as the product of a substantially different cognitive ability – relational priming. To illustrate this, we present a computational (here connectionist) account where analogy arises gradually as a by-product of pattern completion in a recurrent network. Initial exposure to a situation primes (...) a relation that can then be applied to a novel situation to make an analogy. Relations are represented as transformations between states. The network exhibits behaviors consistent with a broad range of key phenomena from the developmental literature, lending support to the appropriateness of this approach (using low-level cognitive mechanisms) for investigating a domain that has normally been the preserve of high-level models. Furthermore, we present an additional simulation that integrates the relational priming mechanism with deliberative controlled use of inhibition to demonstrate how the framework can be extended to complex analogical reasoning, such as the data from explicit mapping studies in the literature on adults. This account highlights how taking a developmental perspective constrains the theory construction and cognitive modeling processes in a way that differs substantially from that based purely on adult studies, and illustrates how a putative complex cognitive skill can emerge out of a simple mechanism. (shrink)

In this book, Cooper brings together psychoanalysis and Zen Buddhism by offering a comprehensive and integrated model, described as "The Realizational Model", that is consistent with the core concepts of Soto Zen Buddhism and psychoanalytic practice. Focusing primarily on Soto Zen Buddhism as presented in the original writings of the Japanese scholar monk Eihei Dōgen (1200-1253), and supported and elaborated by relevant contemporary scholarship in relation to the writings of the British psychoanalyst, Wilfred Bion (1897-1979), this book addresses (...) the issue of how can one understand, assimilate, and integrate conceptions of the human mind that originate in the 13th and 20th Centuries, as they are visited and inflected by the unconscious preconceptions of a 21st-Century perspective. Expressing authentic Buddhist tradition within the frame of psychoanalytic thinking, and supported by online guided audio meditations that accompany the text, this work offers a uniquely interdisciplinary perspective of invaluable clinical significance. Case material garnered from thirty-five years of psychoanalytic practice, as well as examples from daily life support the abstract concepts discussed in the text, rendering it equally relevant for psychoanalysts and psychotherapists, as well as students of Zen wishing to explore its practical applications. (shrink)

David KC Cooper,1 David Ayares21Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USA; 2Revivicor, Blacksburg, VA, USA: The transplantation of organs and cells from pigs into humans could overcome the critical and continuing problem of the lack of availability of deceased human organs and cells for clinical transplantation. Developments in the genetic engineering of pigs have enabled considerable progress to be made in the experimental laboratory in overcoming the immune barriers to successful xenotransplantation. With regard to (...) pig organ xenotransplantation, antibody- and cell-mediated rejection have largely been overcome, and the current major barrier is the development of coagulation dysregulation. This is believed to be due to a combination of immune activation of the vascular endothelial cells of the graft and molecular incompatibilities between the pig and primate coagulation–anticoagulation systems. Pigs with new genetic modifications specifically directed to this problem are now becoming available. With regard to less complex tissues, such as islets, neuronal cells, and corneas, the remaining barriers are less problematic, and graft survival in nonhuman primate models extends for >1 year in all three cases. In planning the initial clinical trials, consideration will be concentrated on the risk–benefit ratio, based to a large extent on the results of preclinical studies in nonhuman primates. If the benefit to the patient is anticipated to be high, eg, insulin-independent control of glycemia, and the potential risks low, eg, minimal risk of transfer of a porcine infectious agent, then a clinical trial would be justified.Keywords: infection, pigs, genetically-engineered, xenotransplantation, islets, xenotransplantation, organs. (shrink)

History ended, according to Hegel according to Kojève, with the establishment and proliferation in Europe of states organized along Napoleonic lines: rational, bureaucratic, homogenous, atheist. This state lives in some tension with the popular slogan that helped give it birth: Liberty, Equality, Fraternity. But there is now also totalitarianism – the only new kind of regime, according to Arendt, created since the national state. Man is now in charge of nature, technology, and society; much of political life has become a (...) gavotte elaborating the meaning of the Napoleonic model. This interpretation, however opposed it seems to common sense, has been influential, particularly in France where the course of existentialism is unintelligible without taking it into account. Professor Cooper argues that it is inherently plausible and examines the arguments of Hegel and Kojève to reveal its consistency and explanatory power. And he applies it to more contemporary events – the experience of the atomic bomb, the Gulag system of extermination, and the growth of multinational corporations. The work concludes by pulling together the presuppositions and theories of the totalitarian system, the Hegelian version of the Napoleonic state, and our contemporary technological society. Overall, the reader will find here a complete and challenging presentation of how the modern world understands its collective life. (shrink)

It has been suggested that the enterprise of developing mechanistic theories of the human cognitive architecture is flawed because the theories produced are not directly falsifiable. Newell attempted to sidestep this criticism by arguing for a Lakatosian model of scientific progress in which cognitive architectures should be understood as theories that develop over time. However, Newell's own candidate cognitive architecture adhered only loosely to Lakatosian principles. This paper reconsiders the role of falsification and the potential utility of Lakatosian principles (...) in the development of cognitive architectures. It is argued that a lack of direct falsifiability need not undermine the scientific development of a cognitive architecture if broadly Lakatosian principles are adopted. Moreover, it is demonstrated that the Lakatosian concepts of positive and negative heuristics for theory development and of general heuristic power offer methods for guiding the development of an architecture and for evaluating the contribution and potential of an architecture's research program. (shrink)

In an era when public faith in politicians is dwindling, yet trust in scientists remains relatively high, governments are increasingly emphasizing the role of science based policy-making in response to challenges such as climate change and global pandemics. In this paper we question the quality of some scientific advice given to governments and the robustness and transparency of the entire framework which envelopes such advice, all of which raise serious ethical concerns. In particular we focus on the so-called Imperial (...) class='Hi'>Model which heavily influenced the government of the United Kingdom in devising its response to the COVID-19 crisis. We focus on and highlight several fundamental methodological flaws of the model, raise concerns as to the robustness of the system which permitted these to remain unchallenged, and discuss the relevant ethical consequences. (shrink)

Teacher and author Vivian Paley is highly regarded by parents, educators, and other professionals for her original insights into such seemingly everyday issues as play, story, gender, and how young children think. In _The Classrooms All Young Children Need_, Patricia M. Cooper takes a synoptic view of Paley’s many books and articles, charting the evolution of Paley’s thinking while revealing the seminal characteristics of her teaching philosophy. This careful analysis leads Cooper to identify a pedagogical model organized around two (...) complementary principles: a curriculum that promotes play and imagination, and the idea of classrooms as fair places where young children of every color, ability, and disposition are welcome. With timely attention paid to debates about the reduction in time for play in the early childhood classroom, the role of race in education, and No Child Left Behind, _The Classrooms All Young Children Need_ will be embraced by anyone tasked with teaching our youngest pupils. (shrink)

A fundamental philosophical question that arises in connection with evolutionary theory is whether the fittest patterns of behavior are always the most rational. Are fitness and rationality fully compatible? When behavioral rationality is characterized formally as in classical decision theory, the question becomes mathematically meaningful and can be explored systematically by investigating whether the optimally fit behavior predicted by evolutionary process models is decision-theoretically coherent. Upon investigation, it appears that in nontrivial evolutionary models the expected behavior is not always in (...) accord with the norms of the standard theory of decision as ordinarily applied. Many classically irrational acts, e.g. betting on the occurrence of one event in the knowledge that the probabilities favor another, can under certain circumstances constitute adaptive behavior.One interesting interpretation of this clash is that the criterion of rationality offered by classical decision theory is simply incorrect (or at least incomplete) as it stands, and that evolutionary theory should be called upon to provide a more generally applicable theory of rationality. Such a program, should it prove feasible, would amount to the logical reduction of the theory of rational choice to evolutionary theory. (shrink)

The politics of precarity have emerged on the contemporary scene of critical theory with great social force in recent years. This paper looks at the risks and obstacles of positing precariousness and vulnerability as the basis of a universal ethics while also arguing for the socially transformative potential of such a model. More broadly, it considers the crucial question of what stands in the way of human relation and ethical life in an age of neoliberalism and biopolitics, and posits (...) an ethics of resemblance grounded in the commonality of flesh and in the at once singular and universal experience of loss. (shrink)

This paper develops the idea, articulated by Martin Buber among others, that a religious sense cannot be identified independently of sensory and practical engagement with the world of ordinary experience. It begins by rejecting the ‘doxastic’ model’ on which religiousness is equated with propositional belief. Criticisms, however, are made of some attempts to soften the contrast between belief and practice. The religious sense, which need not be a theistic one, is understood in terms of a sense of the mystery (...) or ineffability of things – one that has become occluded in modernity. This sense, in turn, is understood in terms of how it may be cultivated and exemplified in and through practices. This claim is elaborated by considering the East Asian notion of ‘Ways’ – practices, like ‘The Way of Tea’, that aim at self-cultivation and spiritual enlightenment. Gardening, in particular, has been regarded as an exemplary Way through which a sense of mystery is cultivated and shaped. The paper concludes by proposing that, when engaged in appropriately and mindfully, almost any ordinary practice may both reflect and confirm an attunement to a mystery that is diffused over the world at large. (shrink)

It is widely mooted that a plausible computational cognitive model should involve both symbolic and connectionist components. However, sound principles for combining these components within a hybrid system are currently lacking; the design of such systems is oftenad hoc. In an attempt to ameliorate this we provide a framework of types of hybrid systems and constraints therein, within which to explore the issues. In particular, we suggest the use of system independent constraints, whose source lies in general considerations about (...) cognitive systems, rather than in particular technological or task-based considerations. We illustrate this through a detailed examination of an interruptibility constraint: handling interruptions is a fundamental facet of cognition in a dynamic world. Aspects of interruptions are delineated, as are their precise expression in symbolic and connectionist systems. We illustrate the interaction of the various constraints from interruptibility in the different types of hybrid systems. The picture that emerges of the relationship between the connectionist and the symbolic within a hybrid system provides for sufficient flexibility and complexity to suggest interesting general implications for cognition, thus vindicating the utility of the framework. (shrink)

Plato in his discussion of the Divided Line introduces a distinction between knowledge of the Forms in and by themselves () and . The first distinguishing characteristic of is that it ‘is compelled to employ assumptions, while knowledge of the Forms tries to advance to a certain first principle’ . The second distinguishing characteristic of is that it employs the ordinary objects of sense-perception as images . The geometer, in order to find out about ‘the Square’ and ‘the Diagonal’, draws (...) diagrams and makes models. (shrink)

Sketching as a scientific practice goes beyond the simple act of inscribing diagrams onto paper. Scientists produce a wide range of representations through sketching, as it is tightly coupled to model-based reasoning. Chemists in particular make extensive use of sketches to reason about chemical phenomena and to communicate their ideas. However, the chemical sciences have a unique problem in that chemists deal with the unseen world of the atomic-molecular level. Using sketches, chemists strive to develop causal mechanisms that emerge (...) from the structure and behavior of molecular-level entities, to explain observations of the macroscopic visible world. Interpreting these representations and constructing sketches of molecular-level processes is a crucial component of student learning in the modern chemistry classroom. Sketches also serve as an important component of assessment in the chemistry classroom as student sketches give insight into developing mental models, which allows instructors to observe how students are thinking about a process. In this paper we discuss how sketching can be used to promote such model-based reasoning in chemistry and discuss two case studies of curricular projects, CLUE and The Connected Chemistry Curriculum, that have demonstrated a benefit of this approach. We show how sketching activities can be centrally integrated into classroom norms to promote model-based reasoning both with and without component visualizations. Importantly, each of these projects deploys sketching in support of other types of inquiry activities, such as making predictions or depicting models to support a claim; sketching is not an isolated activity but is used as a tool to support model-based reasoning in the discipline. (shrink)

Despite the reality of intersex individuals whose biological markers do not necessarily all point towards a traditional binary understanding of either male or female, the vast majority of sports divide competition into categories based on a binary notion of biological sex and develop policies and regulations to police the divide. In so doing, sports governing bodies (SGBs) adopt an imperfect model of biological sex in order to serve their particular purposes, which, typically, will include protecting the fundamental sporting value (...) of fair competition. Yet, one potential consequence of enforcing such an approach would seem to be the exclusion or marginalization of individuals whose biological development does not fit within the binary model, whether due to genetics or through a choice to undergo medical intervention to better represent a chosen gender identity. Any such exclusion or marginalization will inevitably tend to undermine another fundamental value of sport, that of inclusivity. In the context of those with differences of sex development, SGBs appear to be faced with a difficult problem: dealing with a conflict between two fundamental values of sport. Different approaches to this problem have been suggested, with some academics proposing that sports organisations, in general, ought to prioritise fairness above, while others suggest the need to ‘balance’ competing values or even to prioritise inclusion over fairness. However, it is argued that any of these approaches are, in principle, justifiable as any sport should be free to prioritise or balance its own values. What seems more important for any SGB is the need for a rational and transparent justification of regulations that pursue fair competition at the expense of inclusivity. Furthermore, where fair competition and inclusivity are fundamental values, any such justification would seem to demand adherence to some basic norms. First, the regulations should be built on (and articulate) a consistent and principled basis of what ‘fair competition’ means in a particular sport. Second, any regulations should only exclude or restrict participation to the minimum degree necessary to achieve the sense of fair competition so articulated. Third, SGBs should be transparent about what their values are and where their priorities lie so that participants and other stakeholders are able to make an informed choice as to whether they wish to participate in, support, or be associated with a particular sport. With reference to the adoption of the Eligibility Regulations for Athletes with Differences of Sex Development (the ‘DSD Regulations’) by the International Association of Athletic Federations (IAAF), this article seeks to evaluate whether the approach of the IAAF satisfied these basic requirements. (shrink)

We live in the era of Facebook, Fitbit, and Skype. As such, it would be unreasonable to expect that the healthcare industry would not see the same kind of globalization as do our social spheres and consumer activities. Indeed, the explosion of information technology, the ease of transcontinental travel, and the emergence of a more globally aware citizenry allows for scientific collaboration that has had many positive effects on global health. However, the economic and structural disparities between systems of healthcare (...) delivery in the industrialized world and parts of the developing world have created a monster in the form of an international medical tourism industry that endangers the health and safety of citizens of the host country as well as visiting patients. Not only does the practice of medical tourism pose a practical danger to those in direct contact with the industry, but it brings up troubling philosophical problems centering on national responsibility and the commodification of healthcare, among other important issues. In the United States, the driving force behind international medical tourism is the exorbitant cost of healthcare, particularly for the uninsured but also for the underinsured and those who experience catastrophic medical expenses from chronic illness or sudden health crises. Not only have individuals begun to look outside the U.S. for surgical procedures and other expensive therapies, but employers have begun to toy with the idea of outsourcing the medical care of the employees they insure in order to cut costs. In other industrialized nations, the issues that underpin international medical tourism are related to healthcare rationing and reflect different shortcomings in the delivery of healthcare in those nations, such as the United Kingdom and Canada, that have single-payer systems. Yet the regulatory and philosophical implications for both patients and hosts of international healthcare are largely the same. The challenge of regulating international trade in medical care is obvious and becomes particularly acute when there are insurers and employers involved. Complicating matters further, medical care that takes place outside the country of origin of the patient is often brokered by “medical concierge services,” which, though quick to claim indemnity from any harm arising from substandard or inappropriate medical care, cannot be divorced from responsibility for the health outcomes of their clients. Agreements hashed out between concierge services and patients specify that any remedy for harm stemming from their medical care must be pursued within the confines of the law of the host country, but the practical implications of this are troublesome. How can a foreign patient—often without either linguistic or cultural competency in the host country—be expected to navigate the complexity of a foreign legal system, particularly one that may be far less developed than his home country? Furthermore, if insurance companies and employers are involved with such care, who pays for an adverse result or determines responsibility for harm that may befall the patient? Under which countries’ laws? If a patient travels to Singapore for sexual reassignment surgery or a cardiac valve repair, returns to the States and suffers complications, who pays for the restoration of her health? Beyond legal standards and judicial remedies for harm to patients seeking care on the international market, there is the question of what ethical standards and norms apply to such patients. What effect does it have on American patients, for example, to receive care within a system that does not emphasize autonomy and informed consent the way they are used to? Why should foreign physicians care about the cultural mores of their patients’ country of origin? Can they be expected to grasp cultural differences between American, Canadian, and British patients? The medical concierge might respond, “Well, buyer beware!” This is unreasonable: It is nearly impossible for any patient to accurately assess the various options, risks and benefits that go with a particular medical treatment, much less the patient who is attempting to do so on the international market. And the crass invocation of the doctrine of caveat emptor betrays a view of healthcare as a commodity that is naive and inappropriate. Paramount in my mind, however, are the practical implications for the care of the citizens of developing nations that host international patients and the broader philosophical issue of what the goals of the medical profession as a whole and each country’s individual healthcare system should be. While I understand the argument that international medical tourism creates great economic gains for developing nations, which can then be channeled toward the care of their citizenry as a whole, there is much reason to doubt that this “trickle-down” model of economics provides real benefits for underserved, whether in healthcare or other arenas. What is more likely is that, while lucrative international “medi-cities” may keep bright doctors in their home countries, it is also likely to lure them away from the institutions that serve the lion’s share of their countrymen. With the concentration of talented native doctors in private hospitals that serve citizens of the developed world, the population at large is left to obtain care at institutions that suffer “brain drain” from the flight of talented local staff to more prestigious, often “brand name,” institutions that give them more Western-like salaries while allowing them to practice in their countries of origin. The very fact that citizens of the wealthiest nations in the world are forced to go abroad for life-saving care speaks to an abdication of national responsibility on the part of their home countries. The provision of health care is one of the principal responsibilities of any nation and it is unacceptable that a nation with the strength and wealth of the United States would take advantage of the weaker political and economic situations of developing nations in order to shirk its responsibility to its fellow citizens. If we take care of our countrymen and take pride in an equitable system of healthcare delivery, there will be no need to shrug our shoulders and say “Buyer beware” to the patient who heads to the Philippines for heart surgery. (shrink)

Recent new paradigms of computation, based on biological and physical models, address in a radically new way questions of efficiency and challenge assumptions ...

Within the community of researchers applying type theory to natural language there have been proposals to use contexts from type theory to model information states and to use context extension to model information updates. Examples of this are Ranta (1994) and research conducted in the DenK project (e.g. Ahn, 1995, Ahn and Borghuis, 1998).

The paper examines two forms of naturalistic moral realism, “Micro-structure realism” and “Reason realism” . The latter, as we defend it, locates the objectivity of moral facts in socially constructed reality, but the former, as exemplified by David Brink\'s model of naturalistic moral realism, secures the objectivity of moral facts in their micro- structure and a nomic supervenience relationship. We find MSR\'s parity argument for this account of moral facts implausible; it yields a relation ship between moral facts and (...) their natural- scientific constitution that has a queer, slapped- together quality. We argue that the relationship needs to be spelled out by a process of social construction, involving collective intentionality and constitutive rules. We explain how our constructivist model of RR differs from a form of it defended by Michael Smith , which analyzes moral facts by reference not to construction but rather to a hypothetical situation of full rationality. We agree with Smith, as against Bernard Williams, that a rational agent may have reasons for acting that go beyond the agent\'s “subjective motivational set,” but we locate such reasons by reference to the agent\'s member ship in an actual community, and we explore the prospects for moral objectivity given this constraint on moral reasons. (shrink)

Protein splicing is an extraordinary post‐translational reaction that removes an intact central “spacer” domain (Sp) from precursor proteins (N‐Sp‐C) while splicing together the N‐ and C‐domains of the precursor, via a peptide bond, to produce a new protein (N‐C). All of the available data on protein splicing fit a model in which these intervening sequences excise at the protein level via a self‐splicing mechanism. Several proteins have recently been discovered that undergo protein splicing, and in two such cases, the (...) excised spacer protein is an endonuclease. Such endonucleases are capable of conferring genetic mobility upon the intervening sequences that encodes them. These intervening sequences define a new family of mobile genetic elements that are translated yet remain phenotypically silent by excising at the protein rather than the RNA level. (shrink)

One of the claims of Type Theory with Records is that it can be used to model types learned by agents in order to classify objects and events in the world, including speech events. That is, the types can be represented by patterns of neural activation in the brain. This claim would be empty if it turns out that the types are in principle impossible to represent on a finite network of neurons. We will discuss how to represent types (...) in terms of neural events on a network and present a preliminary computational implementation that maps types to events on a network. The kind of networks we will use are closely related to the transparent neural networks discussed by Strannegård. (shrink)

After acquiring knowledge of the neuroscience of learning, memory, stress and emotions, teachers incorporate more cognitive engagement and student-centered practices into their lessons. However, the role understanding neuroscience plays in teachers own affective and motivational competencies has not yet been investigated. The goal of this study was to investigate how learning neuroscience effected teachers’ self-efficacy, beliefs in their ability to teach effectively, self-responsibility and other components of teacher motivation. A pilot training-of-trainers program was designed and delivered in Liberia combining basic (...) neuroscience with information on social, emotional, behavioral and mental health issues faced by students. Tier I of the professional development was a 2 weeks workshop led by a visiting neuroscientist. A subset of the 24 Tier I secondary science teachers formed a Leadership Team who adapted the content to the Liberian context and subsequently led additional workshops and follow-up sessions for the Tier II secondary science teachers. Science teachers in both tiers completed the affective-motivational scales from the internationally vetted, multiscale Innovative Teaching for Effective Learning Teacher Knowledge Survey from the OECD. Tier II teachers completed the survey in a pre-post-delayed post design. Tier I teachers completed the survey after the workshop with their attitudes at that time and separately with retrospective projections of their pre-workshop attitudes. Ten of the 92 Tier II teachers participated in structured interviews at follow-up. Statistical analysis of survey data demonstrated improved teacher self-efficacy, self-responsibility for student outcomes, and motivation to teach. Qualitatively, teachers expressed more confidence in their ability to motivate students, engage them through active learning, and manage the class through positive rather than negative reinforcement. Teachers’ own self-regulation improved as they made efforts to build supporting relationships with students. Together, these results demonstrated that (i) teacher affective-motivational attitudes can be altered with professional development, (ii) basic neuroscience, as knowledge of how students learn, can improve teacher competency, and (iii) a training-of-trainers model can be effective in a low and middle income country for disseminating neuroscience knowledge, increasing teachers’ knowledge of students’ social and emotional needs, and promoting educational improvement. (shrink)

Turing’s paper on computable numbers has played its role in underpinning different perspectives on the world of information. On the one hand, it encourages a digital ontology, with a perceived flatness of computational structure comprehensively hosting causality at the physical level and beyond. On the other, it can give an insight into the way in which higher order information arises and leads to loss of computational control—while demonstrating how the control can be re-established, in special circumstances, via suitable type reductions. (...) We examine the classical computational framework more closely than is usual, drawing out lessons for the wider application of information–theoretical approaches to characterizing the real world. The problem which arises across a range of contexts is the characterizing of the balance of power between the complexity of informational structure and the means available to bring this information back into the computational fold. We proceed via appropriate mathematical modelling to a more coherent view of the computational structure of information, relevant to a wide spectrum of areas of investigation. (shrink)

This article considers the difficulties with using Gillon's model for health care ethics in the context of clinical practice. Everyday difficulties can arise when caring for people from different ethnic and cultural backgrounds, especially when they speak little or no English. A case is presented that establishes, owing to language and cultural barriers, that midwives may have difficulty in providing ethically appropriate care to women of Pakistani Muslim origin in the UK. The use of interpreters is discussed; however, there (...) are limitations and counter arguments to their use. Training is identified as needed to prepare service providers and midwives for meeting the needs of a culturally diverse maternity population. (shrink)

The dilemma confronted by Buridan’s Ass leads into a problem about nil-preference situations, to which there is a solution in the literature that is inspired by Alan Turing: we have evolved with a computational module in our brains that comes into play in such situations by picking a random action among the alternatives that detennines the subject’s choice. We relate these Buridan’s Ass situations to a larger, theoretically interesting category in which there is no alternative that is decisively superior to (...) others with respect to expected utility, and we try to show how our emotional makeup figures in a rational response, particularly as informed by symbolic utilitythat we draw down from our culture’s shared understandings. The category is theoretically interesting because it contains moral dilemmas, as well as hard cases in which an imponant choice must be made without an option that has clearly superior expected utility. We argue that our Emotional Response Model is preferable to Turing’s Randomizer for this category, as well as more illuminating about nil-preference situations or close approximations thereto. (shrink)