Thierry Patrice, 57 ans, médecin, nommé professeur à 32 ans, Lauréat de la Faculté, est internationalement connu pour ses travaux concernant l'action de la lumière sur les tissus vivant en cancérologie. Il a reçu plusieurs Prix pour l'étude du rôle de l'oxygène dans différentes maladies, dont le diabète, mais aussi lors du vieillissement.

On savait que c’était l’entité la plus complexe de l’univers connu. Mais le feu d’artifice de découvertes récentes dépasse l’entendement et fait exploser tous les schémas. Votre cerveau est (beaucoup) plus fabuleux que vous le croyez. Il est : totalement élastique, même âgé, handicapé, voire amputé de plusieurs lobes, le système nerveux central peut se reconstituer et repartir à l’assaut des connaissances et de l’action sur le monde ; totalement social, un cerveau n’existe jamais seul, mais toujours en résonance avec (...) d’autres. Mieux : nous sommes neuronalement constitués pour entrer en empathie avec autrui et aller à son secours. Ce livre aborde ces questions passionnantes avec cinq spécialistes. (shrink)

Rationale In Belgium, several policies regulating reimbursement of acid suppressant drugs and evidence-based recommendations for clinical practice were issued in a short period of time, creating a unique opportunity to observe their effect on prescribing. Aims and objectives To describe the evolution of prescriptions for acid suppressants and explore the interaction of policies and practice recommendations with prescribing patterns. Method Monthly claims-based data for proton pump inhibitors (PPIs) and H-2-antihistamines by general practitioners, internists and "astroenterologists were obtained from the Belgian (...) national health insurance database (1997-2005). The evolution of reimbursed defined daily doses and expenses after introduction of reimbursement regulations and dissemination of practice recommendations was explored. Results Recommendations had no impact on prescribing. All changes can be related to concomitant policies. Lifting reimbursement restrictions for cheaper products did not control growth or save costs in the Iona term. Only restricting reimbursement of all PPIs managed to curb the growth. We observed an unintended increase of non-omeprazole PPIs by gastroenterologists. Conclusions Reimbursement policies influence prescribing, but their effect can be unintended. A dialogue between policymakers and guideline developers, and evidence-based policies that are linked to clinical guidelines, could be an effective way to pursue both cost-containment and quality of care. (shrink)

Research suggested that developing mindfulness skills in children improves proximal outcomes, such as attention and executive functions, as well as distal outcomes, such as academic achievement. Despite empirical evidence supporting this claim, research on the benefits of mindfulness training in child populations is scarce, with some mixed findings in the field. Here, we aimed to fill in this gap, by examining the effects of a mindfulness training on third graders’ proximal and distal outcomes, namely, attention and executive functions (viz., inhibitory (...) control, working memory, and cognitive flexibility) as well as literacy-related achievement (viz., handwriting fluency, text quality, Portuguese grades). These outcomes were measured with behavioral tasks and teacher ratings. Sixty-six Portuguese children were randomly allocated to an experimental group receiving mindfulness training (n= 29) or an active control group receiving relaxation training (n= 37). Both training programs were implemented by psychologists in two 30-min weekly sessions for 8 weeks. All students were assessed before and after the interventions. Three main findings are noteworthy: (a) mindfulness training enhanced teacher-rated cognitive flexibility and a performance-based composite score of executive functions among children with higher pretest scores; (b) relaxation training improved performance-based cognitive flexibility and the composite score of executive functions among children with lower pretest scores; (c) children receiving mindfulness training had higher handwriting fluency and better grades in Portuguese than those receiving relaxation training. These findings provide preliminary evidence on the benefits of mindfulness training in educational settings and highlight the moderating role of baseline performance on those benefits. (shrink)

This paper discusses cross-border projects and their respective social representations to local groups. We present as a case study the boatmen who pilot their boats between Brazil and France on the construction of the Binational Bridge. Catraieiros are currently responsible for much of the logistics between Amapá and French Guiana. Our theoretical framework is based on the literature on Regional Integration and Social Representation. We applied interviews to one third of the catraieiros. We concluded that in the Subject-Representation-Object relationship, the (...) group that understood itself as responsible for the dialogue between two cities built a negative and threatening representation on the Bridge. (shrink)

En mai 2007, une «table ronde» s’est tenue, au Collège International de Philosophie à Paris, autour de l’ouvrage de Pierre Magnard Pourquoi la religion?. Dans un texte récapitulatif, l’auteur du livre, spécialiste de la pensée de la Renaissance, montre les enjeux spéculatifs et pratiques de son approche de la religion, tout en exposant comment celle-ci se déploie dans la «marche» des hommes, en souci de leur humanisation. Si la religion – terme qu’il faut entendre ici au singulier – fait oeuvre (...) de reliaison, apportant sa contribution au fondement du lien social, n’est-ce pas en raison de sa vertu déliante: «seule la religion rassemble dûment, car elle seule est capable de délier»? Jean Leclercq donne une présentation des lignes de faîte de l’ouvrage, ce qui permet d’en prendre une première connaissance et de suivre les trois lectures, accompagnées de questionnements, que proposent ensuite, selon des perspectives différentes et complémentaires, Bernard Bourgeois, Thierry Gontier et Christian Trottmann. (shrink)

Sponges branch basally in the metazoan phylogenetic tree and are believed to be composed of four distinct lineages with still uncertain relationships. Indeed, some molecular studies propose that Homoscleromorpha may be a fourth Sponge lineage, distinct from Demospongiae in which they were traditionally classified. They harbour many features that distinguish them from other sponges and are more evocative of those of the eumetazoans. They are notably the only sponges to possess a basement membrane with collagen IV and specialized cell‐junctions, thus (...) possessing true epithelia. Among Homoscleromorphs, we have chosen Oscarella lobularis as a model species. This common and easily accessible sponge is characterized by relatively simple histology and cell composition, absence of skeleton, and strongly pronounced epithelial structure. In this review, we explore the specific features that make O. lobularis a promising homoscleromorph sponge model for evolutionary and developmental researches. (shrink)

Gperhard Heinzmann, Rédacteur en chef La philosophie est la mère des sciences. Il faut avoir une bonne mémoire pour se le rappeler. Quel bonheur lorsque ce rappel vient d’une collègue qui ne l’a pas appris, mais qui éprouve la nécessité de questionner sa pratique scientifique et actualise ainsi l’ancienne métaphore! C’était le cas de Catherine Dufour. On se connaissait vaguement depuis l’école maternelle des Trois Maisons que fréquentaient nos enfants. Je fus donc très heureux de découvrir,...

Perceptual grouping is fundamental to many auditory processes. The Iambic–Trochaic Law (ITL) is a default grouping strategy, where rhythmic alternations of duration are perceived iambically (weak‐strong), while alternations of intensity are perceived trochaically (strong‐weak). Some argue that the ITL is experience dependent. For instance, French speakers follow the ITL, but not as consistently as German speakers. We hypothesized that learning about prosodic patterns, like word stress, modulates this rhythmic grouping. We tested this idea by training French adults on a German‐like (...) stress contrast. Individuals who showed better phonological learning had more ITL‐like grouping, particularly over duration cues. In a non‐phonological condition, French adults were trained using identical stimuli, but they learned to attend to acoustic variation that was not linguistic. Here, no learning effects were observed. Results thus suggest that phonological learning can modulate low‐level auditory grouping phenomena, but it is constrained by the ability of individuals to learn from short‐term training. (shrink)

Les interventions du sociologue Pierre Bourdieu dans l'espace public datent du début des années 60, à propos de la guerre d'Algérie. Dès lors, il poursuit une réflexion sur les conditions sociales de possibilité de son engagement politique. Ce recueil montre une articulation entre recherche scientifique et intervention politique ; le travail de conversion des pulsions sociales en impulsions critiques. Science sociale et militantisme peuvent être conçus comme les deux faces d'un même travail d'analyse, de décryptage et de critique de la (...) réalité sociale pour aider à sa transformation. (shrink)

When subordinates have suffered an unfairness, managers sometimes try to compensate them by allocating something extra that belongs to the organization. These reactions, which we label as managerial Robin Hood behaviors, are undertaken without the consent of senior leadership. In four studies, we present and test a theory of managerial Robin Hoodism. In study 1, we found that managers themselves reported engaging in Robin Hoodism for various reasons, including a moral concern with restoring justice. Study 2 results suggested that managerial (...) Robin Hoodism is more likely to occur when the justice violations involve distributive and interpersonal justice rather than procedural justice violations. In studies 3 and 4, when moral identity was low, both distributive and interpersonal justice violations showed similar relationships to managerial Robin Hoodism. However, when moral identity was high, interpersonal justice violations showed a strong relationship to managerial Robin Hoodism regardless of the level of distributive justice. (shrink)

A generalized third-order autonomous Duffing–Holmes system is proposed and deeply investigated. The proposed system is obtained by adding a parametric quadratic term m x 2 to the cubic nonlinear term − x 3 of an existing third-order autonomous Duffing–Holmes system. This modification allows the system to feature smoothly adjustable nonlinearity, symmetry, and nontrivial equilibria. A particular attention is given to the effects of symmetric and asymmetric nonlinearity on the dynamics of the system. For the specific case of m = 0, (...) the system is symmetric and interesting phenomena are observed, namely, coexistence of symmetric bifurcations, presence of parallel branches, and the coexistence of four and six symmetric attractors. For m ≠ 0, the system loses its symmetry. This favors the emergence of other behaviors, such as the coexistence of asymmetric bifurcations, involving the coexistence of several asymmetric attractors. All these phenomena have been numerically highlighted using nonlinear dynamic tools and an analog computer of the system. In fact, PSpice simulations of the latter confirm numerical results. Moreover, amplitude control and synchronization strategies are also provided in order to promote the exploitation of the proposed system in engineering. (shrink)

La méconnaissance du virus SARS-CoV-2 et une communication publique déficiente ont contribué à alimenter l’incertitude radicale depuis le début de la pandémie. Cette conjoncture est propice au déferlement de contre-discours dits complotistes dans les arènes numériques et autres « forums hybrides ». Les institutions publiques et médiatiques, en privilégiant une approche épistémologique basée sur le debunking, échouent à comprendre la préférence d’une frange de la population pour les vérités « alternatives » au détriment des preuves scientifiques. En analysant les formes (...) médiatiques et alèthurgiques d’un tel contre-discours, nous montrons comment il se nourrit de l’incertitude pour asseoir son pouvoir et son autorité, témoignant du retour d’une (mauvaise) parrêsia. (shrink)

The meaning of material artifacts that remain unchanged in form can change through spatial references and through changes in context. In this volume, spatial, historical, topographical, and discursive contextual changes are analyzed in case studies, and their meanings and intersections are critically reflected upon.

'The Matrix Project' comprises two contexts, namely photographic work of architect Thierry Lagrange and the self-reflective trajectory that he developed during his doctorate at KULeuven. Lagrange's practice-based research developed to an autonomous artistic project, in which he studied the signification and nature of observation within a creative process. Through his multifaceted practice as an architect, photographer and researcher, Lagrange developed 'The Matrix Method'; a method that stimulates creativity within different contexts and can be implemented for example in art education. (...) For the Matrix Project, 25 years' worth of photographs was entered into a context of research and presents a new perspective on different ways of seeing in our present visual culture. (shrink)

In this paper, I evaluate recently defended mechanistic accounts of the unity of neuroscience from a metaphysical point of view. Considering the mechanistic framework in general , I argue that explanations of this kind are essentially reductive . The reductive character of mechanistic explanations provides a sufficiency criterion, according to which the mechanism underlying a certain phenomenon is sufficient for the latter. Thus, the concept of supervenience can be used in order to describe the relation between mechanisms and phenomena . (...) Against this background, I show that the mechanistic framework is subject to the causal exclusion problem and faces the classical metaphysical options when it comes to the relations obtaining between different levels of mechanisms . Finally, an attempt to improve the metaphysics of mechanisms is made and further difficulties are pointed out. (shrink)

Les travaux de Patrice Bret occupent une place centrale en histoire des sciences et en histoire des techniques. Ce livre entend les mettre à l'honneur, qu'il s'agisse de l'histoire des savoirs académiques, du régime techno-politique du XVIIIe siècle, des interactions entre savants et praticiens à l'heure de la chimie lavoisienne, des circulations culturelles et des traductions ou encore de la place des femmes de sciences. Les contributions réunies dans ce volume illustrent, par leur diversité, l'influence de Patrice Bret (...) dans la communauté historienne. Nous proposons ainsi de mettre en perspective son oeuvre en la replaçant dans un contexte intellectuel, scientifique et épistémologique. Un constat s'impose : loin de distinguer entre les approches conceptuelles, érudites et méthodologiques, Patrice Bret joue un rôle de premier plan dans un milieu scientifique qui a choisi de conjuguer le renouvellement des questionnements avec la production d'instruments de recherche et les interrogations de repérage, de dénomination, d'identification, seules à même de contrer les récits téléologiques qui ont longtemps prévalu dans ce domaine. Si l'histoire des sciences et l'histoire des techniques sont de nos jours à l'avant-poste du renouvellement de la science historique, c'est aussi grâce au rôle de passeur de Patrice Bret. (shrink)

¿Qué significa vivir y filosofar bajo una dictadura militar? Tomaré como punto de partida la experiencia que he compartido con mis amigos chilenos, excluidos o marginados de su universidad, y pronto con otros, argentinos y uruguayos, en las postrimerías de los regímenes autoritarios, una aventura que dura cuarenta años. Al hacerlo, me viene a la memoria la frase de George Eliott que da título al excelente libro de Patrick Vauday, Comenzar. Variaciones sobre la idea de comienzo : “Los hombres no (...) pueden hacer nada sin la ficción de un comienzo”. Es el precio de toda historia o narración, pero “hay sin embargo una necesidad, la de dar cuenta de lo nuevo que no se desprende de lo que le precede sin al menos desviar o derivarse de su línea, como aspirado por lo que aspira a nacer”. (shrink)

This essay investigates the linguistic, artistic, and typographical dimensions of Anne Carson’s H of H Playbook and Trojan Women by Euripides: A Comedy. I argue that graphic design and design-thinking principles provide a useful and unexplored theoretical framework for deciphering these books, given the often-complex relationship in them between image and words, and sometimes even words presented in different typeface and handwriting. Carson worked in graphic design for a time, and as a poet, words – and metaphor, specifically – are (...) her primary design tool. Language works in tandem with image and form to create broader artistic meaning. (shrink)

Simone Weil (1909-1943) foi filósofa, escritora, ativista política e humanista. Nasceu em Paris, no seio de família judaica. Formou-se em filosofia pela Université de Sorbonne e se tornou a primeira mulher catedrática da França. Militou fervorosamente pela causa dos trabalhadores fabris e, posteriormente, lutou na Guerra Civil Espanhola. Faleceu aos trinta e quatro anos por motivos de saúde.[1] [1] Para mais informações, vide texto disponível em:. Acesso em: 25 de junho de 2019.

Malgré sa proximité avec le courant cypherpunk, le secteur des cryptomonnaies n’a pas toujours été fidèle à ses valeurs anarchistes, la finance capitaliste investissant toujours davantage dans les cryptomonnaies pour s’approprier ces nouveaux produits financiers. Cette ambiguïté se retrouve dans les DAO, cette nouvelle forme de gouvernance créée par la technologie blockchain. Cette gouvernance décentralisée est en effet tout à la fois l’expérimentation d’une démocratie radicale, bien qu’asociale, et un retour à une ploutocratie qui peut cacher la violence de ses (...) décisions par l’automatisme des mécanismes informatiques. (shrink)

An adequate analysis of experiences and situations specific to women, especially mothering, requires consideration of women's difference. A focus on women's difference, however, jeopardizes feminism's claims of women's equal individualist subjectivity, and risks recuperating the inequality and oppression of women, especially the view that all women should be mothers, want to be mothers, and are most happy being mothers. This book considers how thinkers including Simone de Beauvoir, Julia Kristeva, Nancy Choderow and Adrienne Rich struggle to negotiate this dilemma of (...) difference in analyzing mothering, encompassing the paradoxes concerning embodiment, gender and representation they encounter. Patrice Di Quinzio shows that mothering has been and will continue to be an intractable problem for feminist theory itself, and suggests the political usefulness of an explicitly paradoxical politics of mothering. (shrink)

The paper argues that a functional reduction of ordinary psychology to neuropsychology is possible by means of constructing fine-grained functional, mental sub-types that are coextensive with neuropsychological types. We establish this claim by means of considering as examples the cases of the disconnection syndrome and schizophrenia. We point out that the result is a conservative reduction, vindicating the scientific quality of the mental types of ordinary psychology by systematically linking them with neuroscience. That procedure of conservative reduction by means of (...) functional sub-types is in principle repeatable down to molecular neuroscience. (shrink)

This book explores the mind-body issue from both the perspectives of philosophy of mind and philosophy of science. Starting from the problem of mental causation, it provides an overview of the contemporary metaphysical discussion and argues in favour of the token-identity thesis, as the only position that can account for the causal efficacy of the mental. Showing furthermore that this ontological reductionism is not dissociable from epistemological reductionism, the author applies a new strategy of inter-theoretic reduction, which is compatible with (...) the multiple realizability of mental properties. Using functionally defined sub-types, this account establishes a conservative reduction of psychology to neuroscience, which vindicates both the scientific legitimacy and the theoretical indispensability of psychology. This account is illustrated by several empirical examples borrowed from contemporary neuroscience. (shrink)