The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO) project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to (...) existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI) and Phenotype Attribute and Trait Ontology (PATO) without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology) and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT)). The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource providing details on the people, policies, and issues being addressed in association with OBI. (shrink)

This book offers both theoretical overviews and practical approaches for educators, academics, education students and parents who are interested in transforming schools. It encourages reinvigorating approaches to learning and teaching that can easily be integrated into both public and private K-12 school classrooms, with many ideas also applicable to higher education. It supports an educational system based on the beliefs that heart and spirit are intertwined with mind and intellect, and that inner peace, wisdom, compassion, and conscience can be developed (...) together with academic content and skills. (shrink)

The global #MeToo movement has precipitated a reckoning with gendered, sexual, and other forms of harassment and bullying in higher education. In academia, harassment is rooted in the history of re...

Many scientists and philosophers claim that some phenomena are emergent, including consciousness, free will, entanglement, ordinary objects, and spacetime. But beyond the rough idea that emergent f...

Background: Facial proportionality and symmetry are positively associated with perceived levels of facial attractiveness. -/- Objective: The aims of this study were to confirm and extend the association of proportionality with perceived levels of attractiveness and character traits and determine differences in attractiveness and character ratings between "anomalous" and "typical" faces using a large dataset. -/- Methods: Ratings of 597 unique individuals from the Chicago Face Database were used. A formula was developed as a proxy of relative horizontal proportionality, where (...) a proportionality score of "0" indicated perfect proportionality and more negative scores indicated less proportionality. Faces were categorized as "anomalous" or "typical" by 2 independent reviewers based on physical features. -/- Results: Across the ratings for all faces, Spearman correlations revealed greater proportionality was associated with attractiveness ( ρ = 0.292, P < 0.001) and trustworthiness ( ρ = 0.193, P < 0.001), while lesser proportionality was associated with impressions of anger (ρ = 0.132, P = 0.001), dominance (ρ = 0.259, P < 0.001), and threateningness ( ρ = 0.234, P < 0.001). Mann-Whitney U tests revealed the typical cohort had significantly higher levels of proportionality (-13.98 versus -15.14, P = 0.030) and ratings of attractiveness (3.39 versus 2.99, P < 0.001) and trustworthiness (3.48 versus 3.35, P < 0.001). -/- Conclusions: This study demonstrated that facial proportionality is not only significantly associated with higher ratings of attractiveness, but also associated with judgements of trustworthiness. Proportionality plays a role in evoking negative attributions of personality characteristics to people with facial anomalies. (shrink)

Strong emergentism is the position that certain higher-level properties display a kind of metaphysical autonomy from the lower-level properties in which they are grounded. The prospect of collapse is a problem for strong emergentism. According to those who press the collapse problem any purportedly strongly emergent feature inheres in the emergence base and so is not genuinely autonomous from that base. Umut Baysan and Jessica Wilson argue that power emergentism avoids the collapse problem. In this paper, I challenge the (...) claim that power emergentism avoids the collapse problem and argue for explanatory emergentism in its place. (shrink)

How do elite universities in the United States and United Kingdom work to meaningfully address decades of deeply embedded institutional racism and classism? They don’t.Continuing their work of expo...

In ‘Three Arguments Against Prescription Requirements’, Jessica Flanigan argues that ‘prescription drug laws violate patients' rights to self-medication’ and that patients ‘have rights to self-medication for the same reasons they have rights to refuse medical treatment according to the doctrine of informed consent , claiming that the strongest of these reasons is grounded on the value of autonomy. However, close examination of the moral value of autonomy shows that rather than being the strongest justification for the DIC, respect for (...) the value of autonomy is actually the weakest, and it is dependent upon the first two well-being-based justifications for the DIC. Recognising this has important implications for Flanigan's argument against prescription requirements. (shrink)

I problematize Grounding-based formulations of physicalism. More specifically, I argue, first, that motivations for adopting a Grounding-based formulation of physicalism are unsound; second, that a Grounding-based formulation lacks illuminating content, and that attempts to imbue Grounding with content by taking it to be a strict partial order are unuseful and problematic ; third, that conceptions of Grounding as constitutively connected to metaphysical explanation conflate metaphysics and epistemology, are ultimately either circular or self-undermining, and controversially assume that physical dependence is incompatible (...) with explanatory gaps; fourth, that in order to appropriately distinguish physicalism from strong emergentism, a Grounding-based formulation must introduce one and likely two primitives in addition to Grounding; and fifth, that understanding physical dependence in terms of Grounding gives rise to ‘spandrel’ questions, including, e.g., “What Grounds Grounding?”, which arise only due to the overly abstract nature of Grounding. (shrink)

An approach to explaining the nature and source of logic and its laws with a rich historical tradition takes the laws of logic to be laws of thought. This view seems intuitively compelling, after all, logic seems to be intimately related with how we think. But how exactly should we understand it? And what arguments can we give in favour? I will propose one line of argument for the claim that the laws of logic are laws of thought. I will (...) motivate the claim that there is a certain phenomenon, namely, that there are logical principles which are immune to rational doubt. I will then give an argument to the best explanation; I will argue that the best explanation of this phenomenon is to take the laws of logic to be constitutive-normative laws of thought. The proposal, and some responses to potential objections, will have a notably Kantian flavour. (shrink)

According to Ian Hacking, some human kinds are subject to a peculiar type of classificatory instability: individuals change in reaction to being classified, which in turn leads to a revision of our understanding of the kind. Hacking’s claim that these ‘human interactive kinds’ cannot be natural kinds has been vehemently criticized on the grounds that similar patterns of instability occur in paradigmatic examples of natural kinds. I argue that the dialectic of the extant debate misses the core conceptual problem of (...) human interactive kinds. The problem is not that these kinds are particularly unstable but ‘capricious’—their members behave in wayward, unexpected manners that defeats existing theoretical understanding. The reason for that, I argue, is that human interactive kinds are often ‘hybrid kinds’ consisting of a base kind and an associated status, which makes mechanisms that support patterns of change and stability systematically difficult to understand and predict. 1Introduction2The Extant Discussion 2.1Hacking’s account of interactive kinds2.2Classificatory feedback in non-human kinds3Natural kinds and Ontological Instability 3.1Understanding instability3.2The problem of stabilizing feedback3.3Summary4Capricious Kinds 4.1Biased conceptualization4.2Studying social status5Conclusion. (shrink)

This article explores the affective dimension of resilient epistemological systems. Specifically, I argue that responsible epistemic practice requires affective engagement with nondominant experiences. To begin, I outline Kristie Dotson's account of epistemological resilience whereby an epistemological system remains stable despite counterevidence or attempts to alter it. Then, I develop an account of affective numbness. As I argue, affective numbness can promote epistemological resilience in at least two ways. First, it can reinforce harmful stereotypes even after these stereotypes have been rationally (...) demystified. To illustrate, I examine the stereotype of Black criminality as it relates to false confessions. Second, it can encourage “epistemic appropriation”, which I demonstrate by examining the appropriation of “intersectionality” and #MeToo by white culture. Finally, I conclude that resisting harmful resilience requires affective resistance, or efforts that target numbness via different kinds of affective engagement. I consider Kantian “disinterestedness” as a candidate. (shrink)

Numerous studies have found that many people believe that a provocatively dressed woman is at greater risk for sexual assault and bears some responsibility for her assault if she is attacked. Furthermore, in legal, academic, and public debates about sexual assault the appropriateness of the term ‘provocative’ as a descriptor of certain kinds of women’s clothing is rarely questioned. Thus, there is a widespread but largely unquestioned belief that it is appropriate to describe revealing or suggestive women’s clothing as ‘provocative’ (...) and that women who wear such clothing could provoke sexual assault and harassment from men. Yet it is rarely noted that only women’s clothing is described as sexually provocative. Men’s clothing, no matter how revealing, is never described as provocative. Why is this the case? This Article challenges the assumption that it is appropriate to describe women’s clothing as provocative. Drawing on on models of the legal defense of provocation and research on objectification and responsibility, this Article demonstrates that continued use of ‘provocative’ term normalizes and entrenches deeply problematic attitudes about women’s responsibility for men’s sexual behavior. The social interpretation of women’s clothing as provocative arises from the privileged social and legal status of men’s sexual arousal and the objectification of women’s bodies. Describing women’s clothing as provocative thus reinforces a problematic conception of women’s bodies and sexuality that is connected to women’s experiences of their bodies, their clothes, and shapes their vulnerability to sexual assault and social and legal attitudes to such attacks. (shrink)

I first discuss Kit Fine's distinctive 'schema-based' approach to metaphysical theorizing, which aims to identify general principles accommodating any intelligible application of the notion, by attention to his accounts of essence and dependence. I then raise some specific concerns about the general principles Fine takes to schematically characterize these notions. In particular, I present various counterexamples to Fine's essence -based account of ontological dependence. The problem, roughly speaking, is that Fine supposes that an object's essence makes reference to just what (...) it ontologically depends on, but various cases suggest that an object's essence can also make reference to what ontologically depends on it, either by way of composition or causation. As such, Fine's account of ontological dependence is subject to the same objection he raises against modal accounts of essence and dependence---that is, of being insufficiently ecumenical. (shrink)

This essay uses the concept of reconstruction to make an argument and an intervention in relation to the practice and study of black aesthetics. The argument will have to do with the parochialism of John Dewey, the institutional inertia of professional philosophy, the aesthetic dimensions of the US politics of reconstruction, the centrality of reconstructionist politics to the black aesthetic tradition, and the staging of a reconstructionist argument in the film, Black Panther (Coogler 2018). The intervention aims to address the (...) fact that arguments like these tend not to register properly because of certain reflexive and customary limits on some common forms of philosophical inquiry. The sort of professional philosophy I was raised to practise and value tends not to be particularly inclusive and open-minded, especially when it comes to subjects that bear directly on the thoughts, lives, and practices of people racialized as black. black aesthetics, by contrast, is an inherently ecumenical enterprise, reaching across disciplinary and demographic boundaries to build communities of practice and exchange. Hence the need for an intervention: to create the space for arguments and the people who work with them to function across disciplinary and demographic contexts. (shrink)

Explanatory realism is the position that all explanations give information about whatever metaphysically determines the explanandum. This view is popular and plays a central role in metaphysics, but in this paper I argue that explanatory realism is false. In Sect. 1 I introduce explanatory realism in its weak and strong versions, and discuss the argumentative work that explanatory realism is used for in contemporary metaphysics. In Sect. 2 I present a series of problem cases for explanatory realism, including explanation by (...) analogy, explanations involving rules, reduction ad absurdum explanations and certain statistical explanations. In Sect. 3 I consider and reject two modified versions of explanatory realism: the position that explanatory realism is true only of explanation in metaphysics, and the position that determinative explanation is the most complete form of explanation. In conclusion I consider explanatory antirealism and explanatory pluralism as alternatives to explanatory realism. (shrink)

This article is an introduction to a philosophical approach termed “panspiritism.” The fundamental principles of this approach are summarized, with discussion of how it links to earlier (mainly Eastern) philosophical perspectives, how it differs from panpsychism and its relationship to idealism and theism. Issues such as the relationship between mind and matter, the relationship between the mind and the brain, and the emergence of mind are discussed from a “panspiritist” perspective. There is a discussion of how panspiritism relates to mystical (...) experiences. The article concludes by suggesting that this approach can help to elucidate a wide range of phenomena that appear anomalous or problematic from a materialist point of view. (shrink)

In 'Stakes and Kidneys' the author discusses various ethical issues surrounding the international trade in human organs.

"Featuring seventeen original essays on the ethics of Artificial Intelligence by some of the most prominent AI scientists and academic philosophers today, this volume represents the state-of-the-art thinking in this fast-growing field and highlights some of the central themes in AI and morality such as how to build ethics into AI, how to address mass unemployment as a result of automation, how to avoiding designing AI systems that perpetuate existing biases, and how to determine whether an AI is conscious. As (...) AI technologies progress, questions about the ethics of AI, in both the near-future and the long-term, become more pressing than ever. Should a self-driving car prioritize the lives of the passengers over the lives of pedestrians? Should we as a society develop autonomous weapon systems that are capable of identifying and attacking a target without human intervention? What happens when AIs become smarter and more capable than us? Could they have greater than human moral status? Can we prevent superintelligent AIs from harming us or causing our extinction? At a critical time in this fast-moving debate, thirty leading academics and researchers at the forefront of AI technology development come together to explore these existential questions, including Aaron James, Allan Dafoe, Andrea Loreggia, Andrew Critch, Azim Shariff, Carrick Flynn, Cathy O'Neil, Eliezer Yudkowsky, Eric Schwitzgebel, Frances Kamm, Francesca Rossi, Hanna Gunn, Iyad Rahwan, Jessica Taylor, JF Bonnefon, K. Brent Venable, Kate Devlin, Mara Garza, Nicholas Mattei, Nick Bostrom, Patrick LaVictoire, Peter Asaro, Peter Railton, S. Matthew Liao, Shannon Vallor, Stephen Wolfram, Steve Petersen, Stuart Russell, Susan Schneider, Wendell Wallach "--. (shrink)

This is the first comprehensive evaluation of Charles Taylor's work and a major contribution to leading questions in philosophy and the human sciences as they face an increasingly pluralistic age. Charles Taylor is one of the most influential contemporary moral and political philosophers: in an era of specialisation he is one of the few thinkers who has developed a comprehensive philosophy which speaks to the conditions of the modern world in a way that is compelling to specialists in (...) various disciplines. This collection of specially commissioned essays brings together twelve distinguished scholars from a variety of fields to discuss critically Taylor's work. The topics range from the history of philosophy, to truth, modernity and postmodernity, theism, interpretation, the human sciences, liberalism, pluralism and difference. Taylor responds to all the contributions and re-articulates his own views. (shrink)

In this essay we argue against preventing people from amassing extreme wealth via increased taxation. The first argument in favor of such a proposal, recently advanced by Ingrid Robeyns (2018), states that billionaires’ resources would be better spent addressing morally important goals such as meeting disadvantaged people’s needs and solving collective action problems. In response to this claim, we argue that billionaires are typically in a better position to benefit the poor and to solve collective action problems than public officials. (...) The second argument in favor of preventing extreme wealth accumulation, advanced by Robeyns and Robert Reich (2018), states that billionaires have an inappropriate amount of influence in public life, which undermines political equality. We argue that corporate leaders tend to be more accountable to their fellow citizens than public officials. We then consider and criticize the objection that billionaires’ success is typically a result of public investment, which entitles public officials to enforce taxes that demand a return on the public investment. (shrink)

Most people have a clear sense of what they mean by disability, and have little trouble identifying conditions they consider disabling. Yet providing a clear and consistent definition of disability is far from straightforward. Standardly, disability is understood as the restriction in our abilities to perform tasks, as a result of an impairment of normal physical or cognitive human functioning. However, which inabilities matter? We are all restricted by our bodies, and are all incapable of performing some tasks, but most (...) of these inabilities are not considered disabilities. If, then, we are to avoid the category of disability becoming overly broad—and thus politically and practically useless—we need some way of picking out the specific inabilities that are disabling. I argue that our answer should be informed by an account of the opportunities individuals are entitled to be able to perform as a matter of justice. Thus, to be disabled is to have these opportunities restricted, and not to deviate from the species norm or lack any ability that might improve our well-being. (shrink)

Equilibrium explanations use an equilibrium to represent and explain a system’s dynamic behavior. They provide a system with the property of global stability: a system will converge towards and remain in equilibrium regardless of its initial conditions and dynamic process. Thus, equilibrium explanations are generally treated as non-causal explanations. There are two claims subsumed under that comprehensive thesis. The first claim is that equilibrium explanations do not identify any causes because a system with global stability resists manipulation. The second claim (...) is that even if equilibrium explanations do identify causes by manipulation, those causes are embedded in a system’s deeper, underlying structural relationships, and those causes are irrelevant to explaining a system’s behavior. Only the system’s structural relationships are relevant. But equilibrium explanations are not monolithic. I compare dynamic systems with multiple, competing equilibria to systems with a globally stable equilibrium. Equilibrium explanations of the former use intervention on a system’s initial conditions and dynamic process to manipulate equilibria, which identifies causes. Furthermore, a system’s initial conditions and dynamic process are relevant to explaining why one equilibrium is selected instead of another. I then apply these lessons to systems with a globally stable equilibrium and discuss when their corresponding equilibrium explanations have a proper role in the parent sciences. (shrink)

ABSTRACTThis article analyzes the moral-psychological stakes of Jay Garfield's reading of Buddhist ethics as moral phenomenology and applies that thesis to the pedagogical mechanisms of the Tibetan Buddhist lojong tradition. I argue that moral phenomenology requires that the practitioner work on a part of her subjectivity not ordinarily accessible to agential action: the phenomenological structures that condition experience. This makes moral phenomenology a highly ambitious ethical project. I turn to lojong as an example of a Buddhist practice that claims to (...) accomplish this ambitious task. As a training toward the ethical ideal of bodhicitta, lojong utilizes practices of meditation and contemplation to disrupt the habitual, affective responses that arise from the conventional phenomenological orientation to the world, replacing them with imagined responses of radically compassionate altruism. This ultimately inculcates a transformation of the phenomenological structures that underlie both ethical action and conscious experience, fulfilling the aim of moral phenomenology. (shrink)

A wealth of research in social psychology indicates that various ethically arbitrary situational factors exert a surprisingly powerful influence on moral conduct. Empirically-minded philosophers have argued over the last two decades that this evidence challenges Aristotelian virtue ethics. John Doris, Gilbert Harman, and Maria Merritt have argued that situationist moral psychology – as opposed to Aristotelian moral psychology – is better suited to the practical aim of helping agents act better. The Aristotelian account, with its emphasis on individual factors, invites (...) too much risk of morally bad conduct insofar as it ignores the power of situational factors which lead us astray. Moral agents are often better off detecting and intervening on situational factors to help themselves act better. This paper offers an argument against the claim that situationism enjoys practical advantages over Aristotelian virtue ethics. There is empirical evidence suggesting that people can improve their behavior via Aristotelian strategies of deliberate self-improvement. This evidence also suggests that focusing our ethical attention on morally trivial factors may result in worse overall conduct. Accordingly, Aristotelianism may fare better than situationism on the practical issue of moral improvement. (shrink)

The COVID-19 pandemic caused an unprecedented and highly threatening, constrained, and confusing social and educational environment, we decided to expand the traditional focus of the extraneous load in Cognitive Load Theory acknowledging the psychological environment in which learning occurs. We therefore adapted and implemented principles of the CLT to reduce extraneous load for our students by facilitating their educational activities. Given previous empirical support for the principles of CLT, it was expected that the adoption of these principles might enable our (...) students to cultivate attitudes and skills across multiple domains such as online learning and presentation technologies, implementing and maintaining a “classroom atmosphere” in a virtual environment, participating in discussions among large online groups of students, facilitating group work, providing virtual office hours for students, and proactively planning for upcoming semesters. (shrink)

Jessica du Toit wonders if our relationship with our pets can be morally defended.

The possibilities of non-invasive prenatal testing (NIPT) are expanding, and the use of NIPT for adult-onset conditions may become widely available in the near future. If parents use NIPT to test for these conditions, and the pregnancy is continued, they will have information about the child’s genetic predisposition from birth. In this paper, we argue that prospective parents should be able to access NIPT for an adult-onset condition, even when they have no intention to terminate the pregnancy. We begin by (...) outlining the arguments against testing in such a situation, which generally apply the same considerations that apply in the predictive testing of a minor to the fetus in utero. We then contend, firstly, that there are important practical considerations that support availability of testing for prospective parents regardless of their stated intentions. Secondly, we object to the ethical equation of a fetus in utero with a minor. We base our analysis on a view of pregnancy that conceptualises the fetus as a part of the gestational parent, as opposed to the more common ‘container’ model of pregnancy. We suggest that fetal information is best conceptualised as shared information between the gestational parent and future child. Thus, it should be approached in similar ways as other kinds of shared information (such as genetic information with implications for family members), where a person has a claim over their own information, but should be encouraged to consider the interests of other relevant parties. (shrink)

Given the long-standing controversy about whether the brain-dead should be considered alive in an irreversible coma or dead despite displaying apparent signs of life, the ethical and policy issues posed when family members insist on continued treatment are not as simple as commentators have claimed. In this article, we consider the kind of policy that should be adopted to manage a family's insistence that their brain-dead loved one continues to receive supportive care. We argue that while it would be ethically (...) inappropriate to continue to devote scarce acute care resources to such patients in a hospital setting, it may not be ethically inappropriate for patients to receive these resources in certain other settings. Thus, if a family insists on continuing to care for their brain-dead loved at their home, we should not, from a policy perspective, interfere with the family's wishes. We also argue that healthcare professionals should make some effort to facilitate the transfer of brain-dead patients to these other settings when families insist on continued treatment despite being informed about the lack of any potential for recovery of consciousness. Our arguments are strengthened by the fact that patients in a persistent vegetative state, who, when correctly diagnosed, also have no potential for recovery of consciousness, are routinely transferred from hospitals to nursing homes or long-term care facilities where they continue to be ventilated, tube fed and to receive other supportive care. We also briefly explore the question of who should be responsible for the costs of such treatment at the long-term care facility. (shrink)

It is a longstanding problem for theorists of justice that many victims of injustice seem to prefer mistreatment, and perpetuate their own oppression. One possible response is to simply ignore such preferences as unreliable ‘adaptive preferences’. Capability theorists have taken this approach, arguing that individuals should be entitled to certain capabilities regardless of their satisfaction without them. Although this initially seems plausible, worries have been raised that undermining the reliability of individuals' strongly-held preferences impugns their rationality, and further excludes already (...) marginalised groups. I argue that such criticisms trade on an ambiguity between two uses of the term ‘adaptive preference’. An adaptive preference is often assumed to be irrational, and an unreliable guide to its possessor's best interests. However, I suggest a preference may also be adaptive in the sense that it is an unreliable guide to our distributive entitlements, and that this does not require an assessment of individuals' rationality. I consider this distinction in relation to disability, arguing that this clarification allows us to justifiably ignore some disabled individuals' preferences, in the context of theorising about distributive justice, without disrespecting or undermining their rationality or culture. (shrink)