Background and Aims Progress towards validating amyloid beta as an early indicator of Alzheimer’s disease (AD) heightens the need for evaluation of stakeholders’ perspectives of the benefits and harms of preclinical testing in asymptomatic individuals. Methods Investigators conducted and analyzed 14 semi-structured interviews with family members of patients diagnosed with AD. Results Participants reported benefits, including the potential to seek treatment, make lifestyle changes, and prepare for cognitive impairment. Participants identified harms, including social harms, adverse life decisions, and psychological harms. (...) Nine participants reported either a “positive global perspective” or a “positive global perspective (qualified).” Conclusion Results from this study characterized stakeholders’ perspectives on the potential benefits and harms of clinical use of preclinical testing for AD. Investigators used data from this study to develop a framework that contributes to ongoing discussions that will evaluate widespread adoption of preclinical testing and will inform future research. (shrink)

Drawn from a wide range of writings and featuring state-of-the-art translations, _Basic Works_ offers convenient access to Thomas Aquinas' most important discussions of nature, being and essence, divine and human nature, and ethics and human action. The translations all capture Aquinas's sharp, transparent style and display terminological consistency. Many were originally published in the acclaimed translation-cum-commentary series _The Hackett Aquinas_, edited by Robert Pasnau and Jeffrey Hause. Others appear here for the first time: Eleonore Stump and Stephen Chanderbahn's translation (...) of _On the Principles of Nature_, Peter King's translation of _On Being and Essence_, and Thomas Williams' translations of the treatises On Happiness and On Human Acts from the Summa theologiae. _Basic Works_ will enable students to immerse themselves in Aquinas's thought by offering his fundamental works without internal abridgements. It will also appeal to anyone in search of an up-to-date, one-volume collection containing Aquinas' essential philosophical contributions--from the Five Ways to the immortality of the soul, and from the nature of happiness to virtue theory, and on to natural law. (shrink)

In a chapter illustrating outrageous words and criminal deeds, Valerius Maximus, the Tiberian editor of exempla, includes in his list of foreign examples reference to an impious son, Mithridates, who fought with his father over who should rule : Mitridates autem multo sceleratius, qui non cum fratre de paterno regno, sed cum ipso patre bellum de dominatione gessit. in quo qui aut homines ullos adiutores inuenerit aut deos inuocare ausus sit, † pare admiratione habet †.

Palmer's defense of libertarianism as consequentialist runs afoul of his own failure to provide any consequentialist reasons for libertarian conclusions, and of his own defense of nonconsequentialist arguments for the intrinsic value of capitalism‐cum‐negative freedom. As suck, Palmer's article exemplifies the parasitic codependency of consequentialist and nonconsequentialist reasoning in libertarian thought. Sciabarra's defense of Ayn Rand's libertarianism is even more problematic, because in addition to the usual defects of libertarianism, Rand adds a commitment to ethical egoism that contradicts both her (...) concern for the consequences of capitalism and her commitment to the rights of everyone, not just herself. (shrink)

Richard Gale, in On the Nature and Existence of God, offers several reasons why an “historical-cum-indexical” theory of reference cannot be appropriate in explaining how people refer to God. The present paper identifies five distinct lines of argument in Gale, attempts to clarify several important desiderata for a successful theory of reference, and argues that Gale fails to discharge the burden of proof he has assumed, leaving the most important features of Alston’s “direct reference” theory untouched. Nevertheless, it is conceded (...) that some consequences of Alston’s theory are quite counter-intuitive. The paper therefore concludes with a consideration of two alternatives: either taking a hard, Alstonian line in conflict with people’s linguistic intuitions, or striking a compromise with descriptivism along lines similar to those found in Gareth Evans’s paper, “The Causal Theory of Names.”. (shrink)

(2003). Introduction: ideas, intellectuals and the public. Critical Review of International Social and Political Philosophy: Vol. 6, The Public Role of Intellectuals, pp. 1-7. doi: 10.1080/1369823042000241221.

Should we make significant sacrifices to ever-so-slightly lower the chance of extremely bad outcomes, or to ever-so-slightly raise the chance of extremely good outcomes? *Fanaticism* says yes: for every bad outcome, there is a tiny chance of extreme disaster that is even worse, and for every good outcome, there is a tiny chance of an enormous good that is even better. I consider two related recent arguments for Fanaticism: Beckstead and Thomas's argument from *strange dependence on space and time*, and (...) Wilkinson's *Indology* argument. While both arguments are instructive, neither is persuasive. In fact, the general principles that underwrite the arguments (a *separability* principle in the first case, and a *reflection* principle in the second) are *inconsistent* with Fanaticism. In both cases, though, it is possible to rehabilitate arguments for Fanaticism based on restricted versions of those principles. The situation is unstable: plausible general principles tell *against* Fanaticism, but restrictions of those same principles (with strengthened auxiliary assumptions) *support* Fanaticism. All of the consistent views that emerge are very strange. (shrink)

How do societies improve over time? This paper demonstrates one means through which the independent actions of individuals can produce country-level social change. We explain how institutional governance norms, specifically those surrounding rule of law, are transmitted to developing countries through migrants and their remittances. We develop and test an empirical model using a panel dataset of 49 developing countries from 2001-2010. Results suggest that migrants and their remittances matter, but their impact depends on where both reside abroad. Developing countries (...) that suffer a “brain drain” may in some cases be compensated with a social gain. (shrink)

Eliminativists sometimes invoke evolutionary debunking arguments against ordinary object beliefs, either to help them establish object skepticism or to soften the appeal of commonsense ontology. I argue that object debunkers face a self-defeat problem: their conclusion undermines the scientific support for one of their premises, because evolutionary biology depends on our object beliefs. Using work on reductionism and multiple realizability from the philosophy of science, I argue that it will not suffice for an eliminativist debunker to simply appeal to some (...) object-free surrogate theory of evolution that results from converting any scientific proposition about some object K into a proposition about simples arranged K-wise. In the process, I examine some hazards peculiar to eliminative reductions of scientific theories, and propose a trilemma for eliminativists who attempt to recoup generality for ontologically sparse reducing theories by appealing to pluralities of simples arranged K-wise. The paper is intended to define and develop the object debunker’s self-defeat problem for further study, and to clarify some of the ways sparse and abundant ontologies interact with scientific theory. (shrink)

Lewis sender‐receiver games illustrate how a meaningful term language might evolve from initially meaningless random signals (Lewis 1969; Skyrms 2006). Here we consider how a meaningful language with a primitive grammar might evolve in a somewhat more subtle sort of game. The evolution of such a language involves the co‐evolution of partitions of the physical world into what may seem, at least from the perspective of someone using the language, to correspond to canonical natural kinds. While the evolved language may (...) allow for the sort of precise representation that is required for successful coordinated action and prediction, the apparent natural kinds reflected in its structure may be purely conventional. This has both positive and negative implications for the limits of naturalized metaphysics. (shrink)

Everett's relative-state formulation of quantum mechanics is an attempt to solve the measurement problem by dropping the collapse dynamics from the standard von Neumann-Dirac theory of quantum mechanics. The main problem with Everett's theory is that it is not at all clear how it is supposed to work. In particular, while it is clear that he wanted to explain why we get determinate measurement results in the context of his theory, it is unclear how he intended to do this. There (...) have been many attempts to reconstruct Everett's no-collapse theory in order to account for the apparent determinateness of measurement outcomes. These attempts have led to such formulations of quantum mechanics as the many-worlds, many-minds, many-histories, and relative-fact theories. Each of these captures part of what Everett claimed for his theory, but each also encounters problems. (shrink)

Since the work of Gödel and Cohen, which showed that Hilbert's First Problem was independent of the usual assumptions of mathematics, there have been a myriad of independence results in many areas of mathematics. These results have led to the systematic study of several combinatorial principles that have proven effective at settling many of the important independent statements. Among the most prominent of these are the principles diamond and square discovered by Jensen. Simultaneously, attempts have been made to find suitable (...) natural strengthenings of ZFC, primarily by Large Cardinal or Reflection Axioms. These two directions have tension between them in that Jensen's principles, which tend to suggest a rather rigid mathematical universe, are at odds with reflection properties. A third development was the discovery by Shelah of "PCF Theory", a generalization of cardinal arithmetic that is largely determined inside ZFC. In this paper we consider interactions between these three theories in the context of singular cardinals, focusing on the various implications between square and scales, and on consistency results between relatively strong forms of square and stationary set reflection. (shrink)

The Epistemic Objection says that certain theories of time imply that it is impossible to know which time is absolutely present. Standard presentations of the Epistemic Objection are elliptical—and some of the most natural premises one might fill in to complete the argument end up leading to radical skepticism. But there is a way of filling in the details which avoids this problem, using epistemic safety. The new version has two interesting upshots. First, while Ross Cameron alleges that the Epistemic (...) Objection applies to presentism as much as to theories like the growing block, the safety version does not overgeneralize this way. Second, the Epistemic Objection does generalize in a different, overlooked way. The safety objection is a serious problem for a widely held combination of views: “propositional temporalism” together with “metaphysical eternalism”. (shrink)

Epistemic Consequentialism Consequentialism is the view that, in some sense, rightness is to be understood in terms conducive to goodness. Much of the philosophical discussion concerning consequentialism has focused on moral rightness or obligation or normativity. But there is plausibly also epistemic rightness, epistemic obligation, and epistemic normativity. Epistemic rightness is often denoted with talk … Continue reading Consequentialism Epistemic →.

We prove a number of consistency results complementary to the ZFC results from our paper [J. Cummings, M. Foreman, M. Magidor, Canonical structure in the universe of set theory: part one, Annals of Pure and Applied Logic 129 211–243]. We produce examples of non-tightly stationary mutually stationary sequences, sequences of cardinals on which every sequence of sets is mutually stationary, and mutually stationary sequences not concentrating on a fixed cofinality. We also give an alternative proof for the consistency of (...) the existence of stationarily many non-good points, show that diagonal Prikry forcing preserves certain stationary reflection properties, and study the relationship between some simultaneous reflection principles. Finally we show that the least cardinal where square fails can be the least inaccessible, and show that weak square is incompatible in a strong sense with generic supercompactness. (shrink)

Since the work of Gödel and Cohen, which showed that Hilbert's First Problem was independent of the usual assumptions of mathematics, there have been a myriad of independence results in many areas of mathematics. These results have led to the systematic study of several combinatorial principles that have proven effective at settling many of the important independent statements. Among the most prominent of these are the principles diamond and square discovered by Jensen. Simultaneously, attempts have been made to find suitable (...) natural strengthenings of ZFC, primarily by Large Cardinal or Reflection Axioms. These two directions have tension between them in that Jensen's principles, which tend to suggest a rather rigid mathematical universe, are at odds with reflection properties. A third development was the discovery by Shelah of "PCF Theory", a generalization of cardinal arithmetic that is largely determined inside ZFC. In this paper we consider interactions between these three theories in the context of singular cardinals, focusing on the various implications between square and scales, and on consistency results between relatively strong forms of square and stationary set reflection. (shrink)

A common line of thought in contemporary metaethics is that certain facts about the evolutionary history of humans make moral realism implausible. Two of the most developed evolutionary cases against realism are found in the works of Richard Joyce and Sharon Street. In what follows, I argue that a form of moral realism that I call proper-function moral realism can meet Joyce and Street's challenges. I begin by sketching the basics of proper-function moral realism. I then present what I take (...) to be the essence of Street's and Joyce's objections, and I show how proper-function realism answers them. (shrink)

“There are no gaps in logical space,” David Lewis writes, giving voice to sentiment shared by many philosophers. But different natural ways of trying to make this sentiment precise turn out to conflict with one another. One is a *pattern* idea: “Any pattern of instantiation is metaphysically possible.” Another is a *cut and paste* idea: “For any objects in any worlds, there exists a world that contains any number of duplicates of all of those objects.” We use resources from model (...) theory to show the inconsistency of certain packages of combinatorial principles and the consistency of others. (shrink)

This article challenges the idea that it is possible to produce a theory of context. Such a theory, it is argued, is unintelligible by virtue of the fact that it leaves us with no prior rational concepts with which to make sense of or understand a theory of context. This argument is developed in relation to the treatment of context in clinical pragmatics. The article examines how clinicians and experimentalists examine pragmatic disorders in children and adults. This examination, it is (...) contended, ends up distorting the notion of context that is integral to utterance (pragmatic) interpretation. It is argued that this distortion arises when we mistakenly believe that we can assume a metaphysical standpoint in our deliberations about context. (shrink)

We prove a representation theorem for preference relations over countably infinite lotteries that satisfy a generalized form of the Independence axiom, without assuming Continuity. The representing space consists of lexicographically ordered transfinite sequences of bounded real numbers. This result is generalized to preference orders on abstract superconvex spaces.

We consider two ways one might use algorithmic randomness to characterize a probabilistic law. The first is a generative chance* law. Such laws involve a nonstandard notion of chance. The second is a probabilistic* constraining law. Such laws impose relative frequency and randomness constraints that every physically possible world must satisfy. While each notion has virtues, we argue that the latter has advantages over the former. It supports a unified governing account of non-Humean laws and provides independently motivated solutions to (...) issues in the Humean best-system account. On both notions, we have a much tighter connection between probabilistic laws and their corresponding sets of possible worlds. Certain histories permitted by traditional probabilistic laws are ruled out as physically impossible. As a result, such laws avoid one variety of empirical underdetermination, but the approach reveals other varieties of underdetermination that are typically overlooked. (shrink)

Could space consist entirely of extended regions, without any regions shaped like points, lines, or surfaces? Peter Forrest and Frank Arntzenius have independently raised a paradox of size for space like this, drawing on a construction of Cantor’s. I present a new version of this argument and explore possible lines of response.

The Accreditation Board of Engineering and Technology (ABET) has declared that to achieve accredited status, “engineering programs must demonstrate that their graduates have an understanding of professional and ethical responsibility.” Many engineering professors struggle to integrate this required ethics instruction in technical classes and projects because of the lack of a formalized ethics-in-design approach. However, one methodology developed in human-computer interaction research, the Value-Sensitive Design approach, can serve as an engineering education tool which bridges the gap between design and ethics (...) for many engineering disciplines. The three major components of Value-Sensitive Design, conceptual, technical, and empirical, exemplified through a case study which focuses on the development of a command and control supervisory interface for a military cruise missile. (shrink)

The counterpart theorist has a problem: there is no obvious way to understand talk about actuality in terms of counterparts. Fara and Williamson have charged that this obstacle cannot be overcome. Here I defend the counterpart theorist by offering systematic interpretations of a quantified modal language that includes an actuality operator. Centrally, I disentangle the counterpart relation from a related notion, a ‘representation relation’. The relation of possible things to the actual things they represent is variable, and an adequate account (...) of modal language must keep track of the way it is systematically shifted by modal operators. I apply my account to resolve several puzzles about counterparts and actuality. In technical appendices, I prove some important logical results about this ‘representational’ counterpart system and its relationship to other modal systems. (shrink)

The existence of mereological sums can be derived from an abstraction principle in a way analogous to numbers. I draw lessons for the thesis that “composition is innocent” from neo-Fregeanism in the philosophy of mathematics.

David Carr (2002) has argued against the use of developmental theories as a basis for curriculum development in moral education. Although we find common ground with some aspects of Carr's arguments, we disagree with several of his criticisms of the cognitive‐developmental approach to moral education. He confuses romantic ideology (as espoused by Rousseau and others) and progressive ideology (as espoused by Dewey and others); he assumes that developmental theories have no endpoint or final goal from which to structure moral education; (...) and he argues against the use of psychological inquiry to validate a philosophical ought. This paper is an attempt to clarify Carr's arguments and propose a justification for the developmental approach to moral education. (shrink)

Recently in this journal, Jessica Morley and colleagues (AI & SOC 2023 38:411–423) review AI ethics and education, suggesting that a cultural shift is necessary in order to prepare students for their responsibilities in developing technology infrastructure that should shape ways of life for many generations. Current AI ethics guidelines are abstract and difficult to implement as practical moral concerns proliferate. They call for improvements in ethics course design, focusing on real-world cases and perspective-taking tools to immerse students in challenging (...) situations with relatable personal, social and environmental implications. The present paper considers the ACTWith model of moral cognition for use in such training contexts. Morley and colleagues' paper and contemporary literature are reviewed. Whistleblowing as a source for relatable case studies is discussed, and the purpose of ethics education considered. The ACTWith model is introduced, and correlations with contemporaries noted. The ACTWith model has been successfully employed in a broad range of technology ethics courses in the Netherlands and South Korea. Illustrations are offered. Correlations with contemporary efforts are drawn in the context of software engineering. Summary discussion considers strengths and limitations of the ACTWith program. Overall, the paper emphasizes training high-level moral reasoning through guided inquiry education informing lifetime professional practice, and indicates an outstanding need for teachers able to do the job. (shrink)

There is one critical way we honor great tragedies: by never forgetting. Collective remembrance is as old as human society itself, serving as an important source of social cohesion, yet as Jeffrey Andrew Barash shows in this book, it has served novel roles in a modern era otherwise characterized by discontinuity and dislocation. Drawing on recent theoretical explorations of collective memory, he elaborates an important new philosophical basis for it, one that unveils profound limitations to its scope in relation (...) to the historical past. Crucial to Barash’s analysis is a look at the radical transformations that symbolic configurations of collective memory have undergone with the rise of new technologies of mass communication. He provocatively demonstrates how such technologies’ capacity to simulate direct experience—especially via the image—actually makes more palpable collective memory’s limitations and the opacity of the historical past, which always lies beyond the reach of living memory. Thwarting skepticism, however, he eventually looks to literature—specifically writers such as Walter Scott, Marcel Proust, and W. G. Sebald—to uncover subtle nuances of temporality that might offer inconspicuous emblems of a past historical reality. (shrink)

Although separated by the centuries, Anselm and Hegel represent two different developments of the ontological proof. This book guides the reader through an exploration of the perplexing ontological argument from a well-balanced analysis of the works of two significant, yet polar opposite thinkers, Anselm and Hegel.

We start by studying the relationship between two invariants isolated by Shelah, the sets of good and approachable points. As part of our study of these invariants, we prove a form of “singular cardinal compactness” for Jensen's square principle. We then study the relationship between internally approachable and tight structures, which parallels to a certain extent the relationship between good and approachable points. In particular we characterise the tight structures in terms of PCF theory and use our characterisation to prove (...) some covering results for tight structures, along with some results on tightness and stationary reflection. Finally, we prove some absoluteness theorems in PCF theory, deduce a covering theorem, and apply that theorem to the study of precipitous ideals. (shrink)

“Pragmatic encroachers” about knowledge generally advocate two ideas: (1) you can rationally act on what you know; (2) knowledge is harder to achieve when more is at stake. Charity Anderson and John Hawthorne have recently argued that these two ideas may not fit together so well. I extend their argument by working out what “high stakes” would have to mean for the two ideas to line up, using decision theory.

We prove some consistency results about and δ, which are natural generalisations of the cardinal invariants of the continuum and . We also define invariants cl and δcl, and prove that almost always = cl and = cl.

Prior work proposes a view of development of purpose and source of meaning in life as a more or less temporally distal project ideal self-situation in terms of which intermediate situations are experienced and prospects evaluated. This work considers Augustine on ensoulment alongside current work into self as adapted routines to common social regularities of the sort that Augustine found deficient. How can we account for such diversity of self-reported value orientation in terms of common structural dynamics differently developed, embodied (...) and enacted over the life course? This work in progress represents divergent views as different sorts of error theory, and hypothesizes that differential development of spindle neural projections underlies different accounts of error for attentive self-correction through iterative attenuation. Some implications for AI augmentation and value alignment of autonomous agents developed on such a model are briefly entertained. (shrink)