This article discusses common ethical and practical considerations in psychosocial and behavioral research in healthcare. Issues such as appropriate objectives and intent, risk-benefit ratios, research design, and human subject protection are explored. The burden of ethical research design and implementation is placed on the investigator, rather than relying solely on institutional review boards to judge individual projects. The benefit of acquisition of knowledge must be balanced against the burdens of the research on society in general and human subjects specifically. Scientific (...) replication of research is encouraged, unnecessary duplication defined and discouraged, and benefits of true collaboration outlined. Investigators are advised to consider the context, intent, purpose, implementation, and use of information when developing research. The concept of “researcher myopia” is defined as a common stumbling block. It is suggested that academic researchers also look to other disciplines, such as industry, for examples of research that is concise, cost-effective, and reliable. (shrink)

Some properties are discussed of regular polygons that may result from angular homeostatic processes in stable orbit. To characterize these homeostatic polygons we need to discuss the winding number, the sidedness (integer, fractional and irrational), multiplicity, envelopes, and density. A regular (i.e., equilateral, equiangular) polygon may be closed in one revolution about its unique center, in multiple revolutions, or not at all. A homeostatic polygon can be generated only if all vertices are included in a single polygon, which occurs if (...) and only if the number of vertices and the number of revolutions required to complete the polygon are relatively prime. For the homeostatic polygon to have a finite number of sides (without repeating itself) the angle subtended by any two successive vertices at the center must be a rational multiple of 2. Biological implications of these properties are illustrated. (shrink)

From the standpoint of the theory of medicine, a formulation is given of three types of reasoning used by physicians. The first is deduction from probability models (as in prognosis or genetic counseling for Mendelian disorders). It is a branch of mathematics that leads to predictive statements about outcomes of individual events in terms of known formal assumptions and parameters. The second type is inference (as in interpreting clinical trials). In it the arguments from replications of the same process (data) (...) lead to conclusions about the parameters of a system, without calling into question either the probabilistic model or the criteria of evidence. The third is illation (as in the elucidation of symptoms in a patient). It is a process whereby, in the light of the total evidence and the conclusions from the other types of reasoning, one may modify, expand, simplify or demolish a conceptual framework proposed for deductions, and modify the nature of the evidence sought, the criteriology, the axioms, and the surmised complexity of the scientific theory. (The process of diagnosis as applied to a patient may in extreme cases lead to the discovery of an entirely new disease with its own, quite new, set of diagnostic criteria. This course cannot be accommodated inside either of the other two types of reasoning.) Illation has something of the character of Kuhn's scientific revolution in physics; but it differs in that it is the nature, not the degree or frequency of change that distinguishes it from Kuhn's normal science. (shrink)

Background: Relatively little is known about neonatologists' roles in helping families navigate the difficult decision to attempt or withhold resuscitation for a neonate delivering at the threshold...

Aims: The Research Diagnostic Criteria for Temporomandi¬bular Disorders (RDC/TMD) Axis I diagnostic algorithms were demonstrated to be reliable but below target sensitivity and specificity. Empirical data supported Axis I algorithm revisions that were valid. Axis II instruments were shown to be both reliable and valid. An international consensus workshop was convened to obtain recommendations and finalization of new Axis I diagnostic algorithms and new Axis II instruments. Methods: A comprehensive search of published TMD diagnostic literature was followed by review and (...) consensus via a formal structured process by a panel of experts for revision of the RDC/TMD. Results: The recommended Diagnostic Criteria for TMD (DC/TMD) Axis I protocol includes both a valid screener for pain diagnoses and valid criteria for the most common pain-related TMDs and for one intra-articular disorder. The Axis II protocol retains selected RDC/TMD screening instruments augmented with new instruments to better assess the interactions between pain and psychosocial functioning. A comprehensive classification system is also presented. Conclusion: The recommended evidence-based DC/TMD protocol is appropriate for use in both the clinical and research settings. Simple Axis I and II screening tests augmented by validated Axis I and Axis II instruments allow for identification of simple to complex TMD patients. (shrink)

Farm animal welfare is a knowledge domain that can be regarded as a model for new ways of organizing learning and making higher education more responsive to the needs of society. Global concern for animal welfare has resulted in a great demand for knowledge. As a complement to traditional education in farm animal welfare, higher education can be more demand driven and look at a broad range of methods to make knowledge available. The result of an inventory on farm animal (...) welfare, e-learning, learning resources, and open educational resources in three different search engines is presented. A huge amount of information on animal welfare is available on the Internet but many of the providers lock in the knowledge in a traditional course context. Only a few universities develop and disseminate open learning resources within the subject. Higher education institutions are encouraged to develop open educational resources in animal welfare for the benefit of teachers, students, society, and, indirectly, animal welfare. (shrink)

From an Indirect Realist point of view, the Knowledge Argument in the philosophy of perception has been misdirected by its very title. If it can be argued that sense-fields are at their basis no more than evidence, indeed, a part of existence as brute as what is usually termed the 'external', then, if 'knowing' is not essential to sensing, that argument has to be radically reconstructed. Resistance to there being an non-epistemic or 'raw feel' basis for sensing is very fashionable (...) at the moment (e.g. in Davidson, McDowell, Harman), but the present article aims at breaking through it. Scientific facts are adduced to show that sensing can exist without perceiving. It is argued that the part played by motivation in the gathering of knowledge in a feedback system, enhanced by intersubjective linguistic correction in the human case, allows for a ready evolutionary adaptation. One can advance from this to a fresh view of knowledge and rationality which see them at base as part of a folk-psychological method of allowing for continuing disambiguation of what are identified within that method as 'entities' and 'properties'. (shrink)

The central topic for this book is the ethics of treating individuals as though they are members of groups. The book raises many interesting questions, including: Why do we feel so much more strongly about discrimination on certain grounds – e.g. of race and sex - than discrimination on other grounds? Are we right to think that discrimination based on these characteristics is especially invidious? What should we think about ‘rational discrimination’ – ‘discrimination’ which is based on sound statistics? To (...) take just one of dozens of examples from the book. Suppose a landlord turns away a prospective tenant, because this prospective tenant is of a particular ethnicity – arguing that statistics show that one in four of this group have been shown in the past to default on their rent. That seems clearly unfair to people of this ethnicity. But we are routinely being judged in this way – not just on the basis of our ethnicity, but assumptions are made about us and decisions taken about us based on our gender, religion, job, post-code, hobbies, blood-group, nationality, etc. Now suppose that another landlord turns away a convicted criminal, arguing that one in four of convicted criminals have been shown to be unreliable rent payers. Is our intuition the same as before? Should it be? This book is suitable for all students of philosophy, especially those with an interest in applied ethics. (shrink)

The Turing Test (TT), as originally specified, centres on theability to perform a social role. The TT can be seen as a test of anability to enter into normal human social dynamics. In this light itseems unlikely that such an entity can be wholly designed in an off-line mode; rather a considerable period of training insitu would be required. The argument that since we can pass the TT,and our cognitive processes might be implemented as a Turing Machine(TM), that consequently a (...) TM that could pass the TT could be built, isattacked on the grounds that not all TMs are constructible in a plannedway. This observation points towards the importance of developmentalprocesses that use random elements (e.g., evolution), but in these casesit becomes problematic to call the result artificial. This hasimplications for the means by which intelligent agents could bedeveloped. (shrink)

Prior theory – that is theorising on the basis of thought and intuition , as opposed to attempting to explain observed data – inevitably distorts what comes after. It biases us in the selection of our data (the data model) and certainly biases any theorising that follows. It does this because we (as humans) can not help but see the world through our theorising – we are blind without the theoretical “spectacles” described by Kuhn (1962). If a theory has shown (...) to be essentially correct in some domain (i.e. by thorough validation against the target problem or domain) using it as a framework can be helpful, however, if the theory is not mature or even speculative then it can effectively prevent progress . I argue that, although we can not ever completely avoid this sort of bias, we can minimise its effect. Two sources of prior theorising coming from opposite directions are sociology and formal systems – neither of these is inherently biased towards prior theorising, but just happens to be a source for such theorising at the present time. Computer scientists who project the results of interesting models onto society are also guilty of constructing first and fitting later. (shrink)

Over the last two decades judges (and regulators) in all common law jurisdictions have increased their reliance on published medical and scientific literature. During the same period biomedical research has undergone fundamental and unprecedented change. This article explores some of the changes to the location, organization and funding of biomedical research in order to assess their implications for liability and proof. Focusing on peer review and publication, along with reforms promoted by the editors of some of the world's pre-eminent general (...) medical journals (e.g. British Medical Journal, the Lancet, Journal of the American Medical Association and the New England Journal of Medicine), this article considers how judges might respond to recent findings which suggest that corporate sponsorship systematically biases biomedical research. Given that common law judges have been reforming rules of evidence and procedure in search of impartial expertise and privileging published biomedical research, how should they respond to the strategic manipulation of the scientific record? (shrink)

We consider here issues of open access to social simulations, with a particular focus on software licences, though also briefly discussing documentation and archiving. Without any specific software licence, the default arrangements are stipulated by the Berne Convention (for those countries adopting it), and are unsuitable for software to be used as part of the scientific process (i.e. simulation software used to generate conclusions that are to be considered part of the scientific domain of discourse). Without stipulating any specific software (...) licence, we suggest rights that should be provided by any candidate licence for social simulation software, and provide in an appendix an evaluation of some popularly used licences against these criteria. (shrink)

Theophrasti Characteres recensuit Hermannus Diels. Oxford Classical Texts. 1909. 3s. 6d. net. Pp. xxviii + .Θεοφρστου Xαρακτxs22EFρες. The Characters of Theophrastus. An English Translation from a Revised Text. With Introduction and Notes by R. C. Jebb, M.A. A new edition. Edited by J. E. Sandys, Litt.D. Macmillan. 1909. 7s. 6d. net. c. 23×14½. Pp. xvi+229.

In lieu of an abstract, here is a brief excerpt of the content:Hume Studies Volume 30, Number 2, November 2004, pp. 213-236 Pleased and Afflicted: Hume on the Paradox of Tragic Pleasure E. M. DADLEZ How fast can you run? As fast as a leopard. How fast are you going to run? A whistle sounds the order that sends Archie Hamilton and his comrades over the top of the trench to certain death. Racing to circumvent that order and arriving seconds (...) too late, Archie's friend Frank screams in rage and despair. Archie is cut down before he has run twenty yards. Peter Weir's film Gallipoli is a chronicle of the disastrous Dardanelles campaign of the first World War, but it is also a film about racing. Archie is trained by his uncle Jack to run "as fast as a leopard." The film begins as it ends, with Archie sprinting in response to a whistle. Frank is first shown racing after a train, along with friends who are on their way to enlist. Archie and Frank meet while competing in a race, they race in Cairo once they have enlisted, and they finally race death. From the beginning, Archie has been faster; even at the end he is the first to die. And from the beginning he has swept Frank along in his wake, encouraging him, pushing him, inspiring him, and helping him to positions for which he is inadequately qualified. In the end, Archie's compassion and kindness prompt a decision which has grim consequences both for himself and for hundreds of others. Knowing that his friend fears death in the trenches, Archie recommends Frank as a substitute for himself, a designated message runner. But Frank is not fast enough, and falls short by mere seconds which Archie would not have lost. This is what leads to the failure of the one real effort to countermand the fatal charge. E. M. Dadlez is Professor of Humanities and Philosophy, University of Central Oklahoma, Edmond, OK 73034, USA. e-mail: [email protected] 214 E. M. Dadlez I am an emotional wreck by the time the movie is over, though I should admit that most of my tears are the result of sheer rage. Both my dogs exited the room in some haste once I began to shout at the television and the unpardonably dimwitted British officers who sat sipping tea at a comfortable distance as they gave the order for soldiers to commit suicide. But it isn't just the scope of the real human disaster, or the enormity of the blunder, or the pointlessness of the entire enterprise, or even my renewed conviction that stupidity is, in fact, evil, that is so unsettling. The film unnerves with respect to personal as well as global concerns, focusing attention on the chance of vanity's leading one to undertake responsibilities beyond one's competence, the possibility of advancement or security being achievable only at the expense of another, and the realization of how easy it might be to let those things happen. Gallipoli is a sad, disturbing film, and the spectator is grieved and disturbed in the course of watching it. Yet, having said that, I must own to having a copy in my possession, and to having watched it more than once. I recommend it to friends, offering to lend them my videotape. In fact, I press it on them. I say that it is a terrific, rewarding work which they should take the time to see. How is it that I can describe my experience of the film in such glowing terms and at the same time acknowledge the extreme distress I felt in the course of watching it? How can I reconcile the discordant aspects of my experience? David Hume explores some possible answers in his essay "Of Tragedy."1 He begins by calling attention to the paradox of tragic pleasure: It seems an unaccountable pleasure, which the spectators of a well written tragedy receive from sorrow, terror... and other passions, which are in themselves disagreeable and uneasy. The more they are touched and affected, the more are they delighted with the spectacle.... The whole art of the poet is employed in rousing and supporting the compassion and... (shrink)

Les droits de l'homme sont un ensemble normatif qui donne à tout être humain des droits universels et inaliénables, malgré les différences religieuse, raciale, ethnique ou nationale. Ces droits sont reconnus aux hommes au-delà des droits positifs des différents Etats. De manière fondamentale, ils sont une garantie contre l'exercice arbitraire du pouvoir. Ils sont la réaffirmation forte de l'égalité et de la liberté sans lesquelles on ne peut construire une société démocratique et forte. Malgré cette posture, les droits de l'homme (...) se retrouvent en quête de sens. Le présent ouvrage propose de voir les inflexions des droits de l'homme face au pouvoir des nouvelles puissances, face à la plénitude de l'Etat-nation de façon générale, mais principalement face à l'Etat-africain. Comment, à partir des critiques d'Edmond Burke, de Karl Marx et d'Hannah Arendt, penser la réalité des droits de l'homme? Quel commerce ces trois grands penseurs des droits de l'homme entretiennent-ils. [Source : 4e p. de couverture]. (shrink)

When first published twenty years ago, The Logic of Medicine presented a new way of thinking about clinical medicine as a scholarly discipline as well as a profession. Since then, advances in research and technology have revolutionized both the practice and theory of medicine. In this new, extensively rewritten edition, Dr. Murphy includes changes to show how these different areas of scholarship may affect details of "the logic of medicine" without compromising its fundamental coherence. New to this edition are discussions (...) of the challenge of the flood of new empirical data, new ideas in genetics, molecular biology, homeostasis, pathogenesis, cancer, aging, and Alzheimer's disease. Murphy also comments on such new theoretical topics as dynamic systems, chaos, and fractals and their impact on the burgeoning fields of philosophy and practice of medicine. Written with medical students in mind, the book includes a glossary, many new examples, and problems for solutions with comments on each. An entirely new chapter deals with modeling. Clinicians and researchers will also find the principles thought-provoking and illuminating. (shrink)

In 1736, an 80-year-old Edmond Halley, dignified by the academic robes of his alma mater, Queens College Oxford, sat down at the brush of transplanted Swedish artist Michael Dahl for his final official portrait.1 By the time he posed for Dahl, Halley occupied a rank of distinction among practical philosophers of the early Enlightenment. His manifold achievements included authorship of the first catalogue of stars in the Michael Dahl, “Dr E Halley, Aged 80.” © The Royal Society. southern hemisphere, (...) the laying of actuarial foundations for life insurance and annuities, his correct prediction of the return in 1758, 1835, and 1910 of a bright periodic comet that today bears .. (shrink)

Philosophy Bites brings together the twenty-five best interviews from this hugely successful website.

On 25th October 1946, in a crowded room in Cambridge, Ludwig Wittgenstein and Karl Popper came face to face for the first and only time. The meeting was a disaster, their loud and aggressive confrontation became the stuff of legend. This book tells what really went on in that room.

Twenty-seven of today's leading philosophers each introduce and explore ideas from one of history's greatest minds." -- Cover.

A French philosopher specializing in logic, E. Goblot is especially remembered today for his book, La Barrière et le Niveau, which, because it lays the groundwork for a theory of social distinction, has become a classic of sociology. Generally presented as a simple precursor which merely anticipates the more noteworthy work of P. Bourdieu, La Barrière et le Niveau is in fact a work mobilizing arguments which tap into the reality of a social class, the bourgeoisie, with which E. Goblot (...) is intimately familiar. By adopting a critical and reflexive posture, it is possible to appreciate the extent to which E. Goblot’s familial and professional experience contributed to framing the issues and the theses which he would develop regarding the French bourgeoisie’s social-distinction strategies in the fields of education, sociability, and morality. (shrink)

There are many algorithm texts that provide lots of well-polished code and proofs of correctness. Instead, this book presents insights, notations, and analogies to help the novice describe and think about algorithms like an expert. By looking at both the big picture and easy step-by-step methods for developing algorithms, the author helps students avoid the common pitfalls. He stresses paradigms such as loop invariants and recursion to unify a huge range of algorithms into a few meta-algorithms. Part of the goal (...) is to teach the students to think abstractly. Without getting bogged with formal proofs, the book fosters a deeper understanding of how and why each algorithm works. These insights are presented in a slow and clear manner accessible to second- or third-year students of computer science, preparing them to find their own innovative ways to solve problems. (shrink)

Der Berg, a poem written between 1906 and 1907, is perhaps one of the most emblematic places to approach the relationship between Rainer Maria Rilke and the East. The mountain we are speaking of is Fujiyama, to which the celebrated Japanese painter Katsushika Hokusai dedicated two woodcut cycles. Presumably, Rilke came into contact with Japanese art through Edmond Goncourt, who had devoted precisely to Hokusai a major critical study in 1908. Another version of the story sees Rilke as having (...) read the monograph on Hokusai by Friedrich Perzynski, published in 1904 in the same series where Rilke’s Worpswede was issued. But let us read the text first:On several occasions, the artist tried to capture the.. (shrink)

In 1766 philosopher, novelist, composer, and political provocateur Jean-Jacques Rousseau was a fugitive, decried by his enemies as a dangerous madman. Meanwhile David Hume—now recognized as the foremost philosopher in the English language—was being universally lauded as a paragon of decency. And so Rousseau came to England with his beloved dog, Sultan, and willingly took refuge with his more respected counterpart. But within months, the exile was loudly accusing his benefactor of plotting to dishonor him—which prompted a most uncharacteristically violent (...) response from Hume. And so began a remarkable war of words and actions that ensnared many of the leading figures in British and French society, and became the talk of intellectual Europe. Rousseau's Dog is the fascinating true story of the bitter and very public quarrel that turned the Age of Enlightenment's two most influential thinkers into deadliest of foes—a most human tale of compassion, treachery, anger, and revenge; of celebrity and its price; of shameless spin; of destroyed reputations and shattered friendships. (shrink)

La 4e de couverture indique : "Cet ouvrage est écrit à quatre mains et porte sur la relation entre création artistique et sciences de la cognition. L'ouvrage propose deux approches de l'expérience esthétique. Une approche en troisième personne mobilisant des modèles propres aux systèmes dits auto-organisateurs issus de la biologie dédiée à la réception des œuvres d'art et une approche en première personne rendant compte par auto-analyse d'une pratique artistique vécue qui s'appuie également sur de tels systèmes, systèmes eux-mêmes liés (...) aux concepts d'émergence et de complexité". (shrink)