We critically review themushrooming literature addressing the neuralmechanisms of moral cognition (NMMC), reachingthe following broad conclusions: (1) researchmainly focuses on three inter-relatedcategories: the moral emotions, moral socialcognition, and abstract moral reasoning. (2)Research varies in terms of whether it deploysecologically valid or experimentallysimplified conceptions of moral cognition. Themore ecologically valid the experimentalregime, the broader the brain areas involved.(3) Much of the research depends on simplifyingassumptions about the domain of moral reasoningthat are motivated by the need to makeexperimental progress. This is a (...) valuablebeginning, but as more is understood about theneural mechanisms of decision-making, morerealistic conceptions will need to replace thesimplified conceptions. (4) The neuralcorrelates of real-life moral cognition areunlikely to consist in anything remotely like a``moral module'' or a ``morality center.'' Moralrepresentations, deliberations and decisionsare probably highly distributed and notconfined to any particular brainsub-system. Discovering the basic neuralprinciples governing planning, judgment anddecision-making will require vastly more basicresearch in neuroscience, but correlatingactivity in certain brain regions withwell-defined psychological conditions helpsguide neural level research. Progress on socialphenomena will also require theoreticalinnovation in understanding the brain'sdistinctly biological form of computationthat is anchored by emotions, needs, drives,and the instinct for survival. (shrink)

Hegel introduced the Phenomenology of Mind as a work on the problem of knowledge. In the first chapter, entitled “Sense Certainty, or the This and Meaning,” he concluded that knowledge cannot consist of an immediate awareness of particulars ). The tradition discusses sense certainty in terms of this failure of immediate knowledge without, however, specifically addressing the problem of reference. Yet reference is distinct from knowledge in the sense that while there can be no knowledge of objects without reference, there (...) may be reference without knowledge. If that is the case, then the failure of immediate knowledge does not entitle us to conclude anything about the success or failure of reference. It is not surprising, then, that a few scholars have begun to examine sense certainty primarily as a thesis about reference. (shrink)

The AAR-SBL Women’s Caucus session on ‘Beyond Down and Dirty: From Good to Great Sex’ revisited the Good Sex: Feminist Perspectives from the World’s Religions project and book with the participation of two of its co-editors, Mary E. Hunt and Patricia Beattie Jung, and co-author and collaborator, Wanda Defeilt. Scholar colleagues, Brandy Daniels, Fitri Junoes, and Alicia Besa Panganiban, presented intriguing papers on feminist religious and ethical reflections on what constitutes great sex as they examined the issues discussed by (...) feminist scholars and activist authors of Good Sex. Moreover, the session was an exhilarating dialogue of international, interreligious, and intergenerational perspectives on what women think is great sex. It was an exciting starting ground for intergenerational discussion with senior scholars, associated with the Good Sex book, providing generous, constructive, and well-considered responses to the presentations of their colleagues. The diverse international audience of masters, doctoral and senior scholars – male and female – was included in the complex, fun, and challenging discussion of sex. Amidst various issues raised, there was a consensus that discussions on great sex must address issues of safety, justice, and pleasure. Overall the session was a success as the platform for the presentations modelled a feminist method that was intentionally designed to give more time for discussion, not only among panelists but also with the audience. (shrink)

This paper considers the process of becoming an international public intellectual, taking the case of Maria Montessori (1870–1952), the Italian physician who became an authority on education and, u...

Informed consent documents are central to the informed consent process and are required for participation in clinical trials in the U.S. The primary purpose of the document is “to assist a prospect...

The value of any kind of data is greatly enhanced when it exists in a form that allows it to be integrated with other data. One approach to integration is through the annotation of multiple bodies of data using common controlled vocabularies or ‘ontologies’. Unfortunately, the very success of this approach has led to a proliferation of ontologies which itself creates obstacles to integration. The Open Biomedical Ontologies (OBO) consortium has set in train a strategy to overcome this problem. Existing (...) OBO ontologies, including the Gene Ontology, are undergoing a process of coordinated reform and new ontologies being created on the basis of an evolving set of shared principles governing ontology development. The result is an expanding family of ontologies designed to be interoperable, logically well-formed, and to incorporate accurate representations of biological reality. We describe the OBO Foundry initiative, and provide guidelines for those who might wish to become involved. (shrink)

The nm23 gene, a putative metastasis suppressor gene, was originally identified by its reduced expression in highly metastatic K‐1735 murine melanoma cell lines, as compared to related, low metastatic melanoma cell lines. Transfection of nm23 cDNA has been reported to suppress malignant progression in Drosophila and mammalian cells. Highly conserved homologues of nm23 have been found in organisms ranging from the prokaryote Myxococcus xanthus to Drosophila, where the gene is involved in normal development and differentiation. The product of the nm23 (...) gene exhibits a nucleoside diphosphate kinase activity, yet the nucleoside diphosphate kinase activity of Nm23 does not correlate with its apparent biological functions. We review recent cellular, genetic, biochemical and X‐ray crystallographic data to formulate and evaluate hypotheses concerning the molecular mechanism of nm23 action. (shrink)

At the beginning of 2020, COVID-19 became a global problem. Despite all the efforts to emphasize the relevance of preventive measures, not everyone adhered to them. Thus, learning more about the characteristics determining attitudinal and behavioral responses to the pandemic is crucial to improving future interventions. In this study, we applied machine learning on the multi-national data collected by the International Collaboration on the Social and Moral Psychology of COVID-19 (N = 51,404) to test the predictive efficacy of constructs from (...) social, moral, cognitive, and personality psychology, as well as socio-demographic factors, in the attitudinal and behavioral responses to the pandemic. The results point to several valuable insights. Internalized moral identity provided the most consistent predictive contribution—individuals perceiving moral traits as central to their self-concept reported higher adherence to preventive measures. Similar was found for morality as cooperation, symbolized moral identity, self-control, open-mindedness, collective narcissism, while the inverse relationship was evident for the endorsement of conspiracy theories. However, we also found a non-negligible variability in the explained variance and predictive contributions with respect to macro-level factors such as the pandemic stage or cultural region. Overall, the results underscore the importance of morality-related and contextual factors in understanding adherence to public health recommendations during the pandemic. (shrink)

State Medical Boards (SMBs) can take severe disciplinary actions (e.g., license revocation or suspension) against physicians who commit egregious wrongdoing in order to protect the public. However, there is noteworthy variability in the extent to which SMBs impose severe disciplinary action. In this manuscript, we present and synthesize a subset of 11 recommendations based on findings from our team’s larger consensus-building project that identified a list of 56 policies and legal provisions SMBs can use to better protect patients from egregious (...) wrongdoing by physicians. (shrink)

Just Ecological Integrity presents a collection of revised and expanded essays originating from the international conference "Connecting Environmental Ethics, Ecological Integrity, and Health in the New Millennium" held in San Jose, Costa Rica in June 2000. It is a cooperative venture of the Global Ecological Integrity Project and the Earth Charter Initiative.

BackgroundStructured, systematic methods to formulate consensus recommendations, such as the Delphi process or nominal group technique, among others, provide the opportunity to harness the knowledge of experts to support clinical decision making in areas of uncertainty. They are widely used in biomedical research, in particular where disease characteristics or resource limitations mean that high-quality evidence generation is difficult. However, poor reporting of methods used to reach a consensus – for example, not clearly explaining the definition of consensus, or not stating (...) how consensus group panellists were selected – can potentially undermine confidence in this type of research and hinder reproducibility. Our objective is therefore to systematically develop a reporting guideline to help the biomedical research and clinical practice community describe the methods or techniques used to reach consensus in a complete, transparent, and consistent manner.MethodsThe ACCORD project will take place in five stages and follow the EQUATOR Network guidance for the development of reporting guidelines. In Stage 1, a multidisciplinary Steering Committee has been established to lead and coordinate the guideline development process. In Stage 2, a systematic literature review will identify evidence on the quality of the reporting of consensus methodology, to obtain potential items for a reporting checklist. In Stage 3, Delphi methodology will be used to reach consensus regarding the checklist items, first among the Steering Committee, and then among a broader Delphi panel comprising participants with a range of expertise, including patient representatives. In Stage 4, the reporting guideline will be finalised in a consensus meeting, along with the production of an Explanation and Elaboration document. In Stage 5, we plan to publish the reporting guideline and E&E document in open-access journals, supported by presentations at appropriate events. Dissemination of the reporting guideline, including a website linked to social media channels, is crucial for the document to be implemented in practice.DiscussionThe ACCORD reporting guideline will provide a set of minimum items that should be reported about methods used to achieve consensus, including approaches ranging from simple unstructured opinion gatherings to highly structured processes. (shrink)

Peter Geach famously holds that there is no such thing as absolute identity. There are rather, as Geach sees it, a variety of relative identity relations, each essentially connected with a particular monadic predicate. Though we can strictly and meaningfully say that an individual a is the same man as the individual b, or that a is the same statue as b, we cannot, on this view, strictly and meaningfully say that the individual a simply is b. It is difficult (...) to find anything like a persuasive argument for this doctrine in Geach's work. But one claim made by Geach is that his account of identity is the account most naturally aligned with Frege's widely admired treatment of cardinality. And though this claim of an affinity between Frege's and Geach's doctrines has been challenged, the challenge has been resisted. William Alston and Jonathan Bennett, indeed, go further than Geach to argue that Frege's doctrine implies Geach's. If Alston and Bennett are right, then those who favor a broadly Fregean treatment of cardinality have no choice but to adopt Geach's doctrine of relative identity. And because contemporary set-theoretic accounts of cardinality are essentially Fregean in all respects relevant to this issue (see §11 below), it follows from Alston and Bennett's claim that virtually every standard modern treatment of cardinality requires a 'relativized' treatment of identity. The purpose of this paper is to argue against the implication claimed by Alston and Bennett. Despite some superficial similarities between Frege's treatment of cardinality and Geach's treatment of identity, the two doctrines are fundamentally opposed. Frege's account of cardinality, and its set-theoretic descendants, are all inconsistent with the claim that identity is 'relative' in Geach's sense. (shrink)

This article is an edited version of the response paper offered at the conclusion of the symposium, Modern Sensibilities. It ties together themes from the symposium papers, as well as ideas prompted by Mieke Bal’s exhibition, Emma & Edvard: Love in the Time of Loneliness, and her accompanying book, Emma and Edvard Looking Sideways: Loneliness and the Cinematic. It focuses on the anachronistic entanglements among Flaubert’s “Emma,” Munch’s motifs, Mieke Bal and Michelle Williams Gamaker’s Madame B, the Munch Museum’s architecture (...) and exhibition scenography, and the exhibition viewer. (shrink)

Sont éditées et présentées 24 lettres de Bergson à Salomon Reinach. Outre l'intérêt biographique de cette correspondance, on y trouve trois lettres au moins offrant un véritable intérêt philosophique : une présentation par Bergson de la philosophie de William James et deux lettres sur des aspects de sa propre philosophie, suscitées par la préparation et la parution des Lettres à Zoé. Twenty-four letters from Bergson to Salomon Reinach are edited and presented here. Besides the biographical interest of this correspondence, at (...) least three letters offer a real philosophical interest: a presentation by Bergson of William James's philosophy and two letters on aspects of his own philosophy, prompted by the preparation and the publication of Lettres à Zoé, a book on history of philosophy by Reinach. (shrink)

Although it is now fifteen years since G. Williams' thorough-going criticism of B. Axelson's Unpoetische Wörter, his discussion has failed to elicit the adverse response which might have been expected in view of the widespread influence exerted by the earlier work. The reason for this may be that Axelson's theory is so widely accepted that any refutation thereof may be disregarded. Yet surely Williams was right to point to the dangers of total reliance on statistics and to the necessity of (...) considering the contexts in which words occur in Latin poetry. In this respect, he was not so much rejecting Axelson's work as pointing to its inadequacies: whereas Axelson would be content to label a word that occurs only rarely in poetry as ‘unpoetisch’, it is necessary, as Williams demonstrates, to take the further step of determining the effect that such a word has in a given context. This approach will be particularly helpful, for example, in the case of parvulus at Virg. Aen. 4.328, where the heightened pathos achieved by Virgil's use of a diminutive is better appreciated by the reader who is aware of the scarcity of diminutive adjectives in poetry and in epic above all. To recognise parvulus as an ‘unpoetic word’, with Axelson, is the essential first step, but we should proceed a stage further to inquire what effect was intended by the employment of a form not normally found in elevated poetry. Of greater importance is Williams' rejection of the ‘hierarchy of genres’ theory, taken for granted by Axelson, that is, that Latin poetry may be divided into a number of higher- or lower-ranking genres and that the more elevated a genre the less unpoetic vocabulary it is liable to employ. (shrink)

When George Bernard Shaw described Dartington Hall as a ‘salon in the countryside’, he was referring to the maelstrom of ideas, conversations, and experimentation around psychology, mysticism, and spirituality within the estate's larger ethos of community living and rural reform. Disenchanted with the effects of industrialization and the ravages of the First World War, American railway heiress Dorothy Whitney Elmhirst and her second husband, Leonard Elmhirst, purchased the extensive Devonshire estate in 1925 and began to encourage regular visits and social (...) and spiritual advice from prominent British interwar intellectuals such as Aldous Huxley and Gerald Heard. As the estate's activities expanded during the 1930s, Dorothy enlisted the help of visiting American constitutional psychologist William Sheldon to assess and advise upon the well-being of children attending Dartington's experimental school. Sheldon's ‘Promethean Psychology’ and ‘Somatotyping’ body classification system offered the Dartington group, a social, spiritual, and ‘scientific’ alternative to Freudian understandings of the mind. Visitors such as Huxley, decades later, relied on Sheldon's somatotyping system to fashion a utopian education in Pala (in his last novel, Island) where the population might live in nonmaterialistic cooperative harmony. Dartington's attraction to the use of Sheldon's Promethean psychology in supporting a utopian view of progressive education was as short-lived as were Pala's utopian ambitions decades later. In years to come, however, elements of Sheldon's views continued to find an audience among physical educators and sports scientists, who saw in somatotypes a useful guide for assessing talent identification and future sporting success. (shrink)

En este artículo sobre la poesía testimonial del Caribe colombiano propongo un camino de lectura de los afectos y las imágenes, frente a la violencia y las hegemonías de los discursos pacificadores del siglo XXI. Hago primero un recorrido sobre las tradiciones literarias en relación con la violencia en Colombia. Sin embargo, me centraré en la producción contemporánea, en lo que respecta a publicaciones que se hacen en un momento de posconflicto y de política de la memoria en el siglo (...) XXI. Interpreto la manera en que la imagen poética le responde estética y políticamente a lo que Williams (1980) llamó estructura sentimental de la época. Escojo los poemarios de escritores colombianos caribeños sobre la violencia: “Regresemos a que nos maten amor” (Ariza Navarro 2008), “Al otro lado de la guerra” (Acosta 2014), “Alarmas armadas” (Núñez 2016). Mi tesis es que la poesía testimonial, como flujo estético que viene desde el siglo XX, manifiesta y construye políticas poéticas desde la dialéctica de los afectos, desde la huella de la guerra; se vale de las imágenes para exhibir la violencia, pero crea una sensibilidad que interpela a los lectores sobre lo sentido en una realidad póstuma. (shrink)

The debate over the central issue confronted in Closing--the role of the university and the liberal arts in the United States--has become increasingly urgent and contentious. The goal of this collection of essays is to consider what we can learn about the dilemmas confronting American culture through a consideration of both The Closing of the American Mind and the debate it has aroused. The contributors differ among themselves as to the validity of both the diagnoses and the solutions Bloom offers, (...) yet they do not engage in "Bloom-bashing" or hero-worship. The goal of the book is to place the debate over Closing into the larger context than can be achieved in a book review format. To provide the historical perspective that has been missing in the controversy over Bloom, included in this volume is Christopher Lasch's "The Great Experiment: Where Did it Go Wrong?" Also included are essays by other leading critics: John K. Roth, Frank Caucci, William K. Buckley, Milton R. Stern, Susan Bourgeois, Margaret C. Jones, Daniel Zins, Kenneth Alan Hovey, Bonnie A. Hain, John Peacock, Patricia L. Lundberg, Peter Siedlecki, Mark W. Roche, William Thickstun, Lorraine Clark, and Gerald Graff. This volume of essays does much to illuminate the issue surrounding The Closing of the American Mind. (shrink)

English people have long been renowned for their obsession with the weather: Francis Bacon chose to write about the wind for the first installment of his natural history. Place is central to Vladimir Janković's analysis, so it is highly appropriate that he should focus on England to study the prehistory of quantitative meteorology. Janković's major innovation is to argue that local interests in recording strange weather conditions later became converted into the global concerns of nineteenth‐century scientists. Before then, he maintains, (...) reading the skies was not a science, because it meant engaging with the human rather than the physical environment. Janković demonstrates convincingly that the activities of provincial naturalists, and their concern with investigating abnormal events to strengthen regional identities, played vital roles in altering the observation and interpretation of weather conditions.Meteorology is a tricky discipline to discuss historically because the word's significance has changed dramatically. In Janković's period, the seventeenth and eighteenth centuries, it embraced diverse celestial phenomena—meteors, comets, and the northern lights as well as rain, snow, and so forth. Rather strangely, considering his historical sensitivity, Janković uses the word “meteorology” throughout, a confusing decision. Well organized into seven distinct chapters, Reading the Skies opens by examining how traditional beliefs fashioned weather reports and includes a fine investigation of the political and religious implications of extraordinary phenomena. The central section explores the importance of regional interests in recording weather characteristics for local natural histories. Clergymen were particularly important in maintaining research traditions based on provincial pride, and the career of an erudite Cornish naturalist, Reverend William Borlase, illustrates the relationships between national and local concerns. The final two chapters concentrate on changes toward the end of the period, discussing how agricultural requirements and the demands of metropolitan chemical reformers resulted in shifts away from localized studies based on classical principles. In the early nineteenth century specialized experts and instrument makers were converting the whole world and its atmosphere into their laboratory. They sought to measure ordinary weather accurately so that they could build causal, predictive models.As in many good books, a third is taken up with notes and bibliographies. This type of research involves retrieving fleeting references from a wide range of texts, and the succinct, scholarly prose relies on an impressive breadth of reading. The intriguing illustrations are supplemented by text boxes—framed lists of articles, peoples, and episodes that would normally be relegated to an appendix but that here provide valuable visual evidence to support an argument. Nevertheless, since Reading the Skies claims to be “a cultural history,” it is disconcerting to find that artistic and literary sources have been deliberately excluded. This is very much a gentlemanly account. Little attention is paid to the farmers, laundresses, and other workers for whom weather vagaries were not just diary items but held a very real and practical significance. Women are also absent, even though many men held witches responsible for the unpredictable and freakish behavior of unruly female nature.This is a learned study that engages with historiographical issues yet also provides a wealth of detailed primary information. It empathetically reconstructs the preoccupations of English provincial gentlemen who then, as now, were convinced that England's weather was deteriorating. (shrink)

For two hundred years materialist philosophers have argued that man is some sort of machine. The claim began with French materialists of the Enlightenment such as Pierre Cabanis, Julien La Mettrie, and Baron d’Holbach (La Mettrie even wrote a book titled Man the Machine). Likewise contemporary materialists like Marvin Minsky, Daniel Dennett, and Patricia Churchland claim that the motions and modifications of matter are sufficient to account for all human experiences, even our interior and cognitive ones. Whereas the Enlightenment (...) philosophes might have thought of humans in terms of gear mechanisms and fluid flows, contemporary materialists think of humans in terms of neurological systems and computational devices. The idiom has been updated, but the underlying impulse to reduce mind to matter remains unchanged. (shrink)

Presenting an engaging overview of the Churchlands that is accessible to undergraduate philosophy students and general readers, this title-a volume in the Wadsworth Philosophy Topics Series--provides a concise introduction to this pertinent topic of philosophical interest. The Wadsworth Philosophy Topics Series presents readers with concise, timely, and insightful introductions to a variety of traditional and contemporary philosophical subjects. With this series edited by Daniel Kolak of the William Paterson University of New Jersey, philosophy students will be able to discover the (...) richness of philosophical inquiry across a wide array of concepts, including hallmark philosophical themes and topics typically underrepresented in mainstream philosophy publishing. Written by a distinguished list of scholars who have been noted for their exceptional teaching abilities, this series presents the vast sweep of today's philosophical exploration in highly accessible and affordable volumes. These books will prove valuable to philosophy teachers and their students as well as to other readers who share a general interest in philosophy. (shrink)

Patricia Williams made a number of claims concerning the methods and practise of cladistic analysis and classification. Her argument rests upon the distinction of two kinds of hierarchy: a divisional hierarchy depicting evolutionary descent and the Linnean hierarchy describing taxonomic groups in a classification. Williams goes on to outline five problems with cladistics that lead her to the conclusion that systematists should eliminate cladism as a school of biological taxonomy and to replace it either with something that is philosophically (...) coherent or to replace it with pure methodology, untainted by theory (Williams 1992, 151). Williams makes a number of points which she feels collectively add up to insurmountable problems for cladistics. We examine Williams' views concerning the two hierarchies and consider what cladists currently understand about the status of ancestors. We will demonstrate that Williams has seriously misunderstood many modern commentators on this subject and all of her five persistent problems are derivable from this misunderstanding. Some persons believe and argue, on grounds approaching faith it seems to me, that phylogeny comes from our knowledge of evolution. Others have found to their surprise, and sometimes dismay, that phylogeny comes from our knowledge of systematics. Nelson (1989, 67). (shrink)

The Tobacco Control Legal Consortium is a national “network” designed to tap expertise about tobacco control legislation and to leverage existing resources. Based at the William Mitchell College of Law in St. Paul, Minnesota, the Consortium supports local counsel with research, strategic advice, sample materials and pleadings, and amicus briefs. The Consortium’s priorities are to support capacity nationally, to offer education, and to perform outreach activities to a variety of audiences.The Consortium seeks to advance policy change by making legal expertise (...) more readily available to the tobacco control community. Legal issues are inevitably involved in policy change. The Consortium does not provide legal representation, but conducts analysis and research. They publish on important and emerging legal issues as well as on specific cases, assist in the development of legislation, and train public health practitioners and policy makers on recurring legal issues. (shrink)