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  1. Conceptual Engineering of Medical Concepts.Elisabetta Lalumera - forthcoming - In Manuel Gustavo Isaac & Kevin Scharp (eds.), New Perspectives on Conceptual Engineering.
    There is a lot of conceptual engineering going on in medical research. I substantiate this claim with two examples, the medical debate about cancer classification and about obesity as a disease I also argue that the proper target of conceptual engineering in medical research are experts’ conceptions. These are explicitly written down in documents and guidelines, and they bear on research and policies. In the second part of the chapter, I propose an externalist framework in which conceptions have both the (...)
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  2. New Directions in Philosophy of Medicine.Jacob Stegenga, Ashley Kennedy, Serife Tekin, Saana Jukola & Robyn Bluhm - forthcoming - In James Marcum (ed.), Bloomsbury Companion to Contemporary Philosophy of Medicine. Bloomsbury Academic. pp. 343-367.
    The purpose of this chapter is to describe what we see as several important new directions for philosophy of medicine. This recent work (i) takes existing discussions in important and promising new directions, (ii) identifies areas that have not received sufficient and deserved attention to date, and/or (iii) brings together philosophy of medicine with other areas of philosophy (including bioethics, philosophy of psychiatry, and social epistemology). To this end, the next part focuses on what we call the “epistemological turn” in (...)
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  3. Unveiling the interplay between evidence, values and cognitive biases. The case of the failure of the AstraZeneca COVID‐19 vaccine.Cristina Amoretti & Elisabetta Lalumera - 2023 - Journal of Evaluation in Clinical Practice 1.
  4. Probability and Informed Consent.Nir Ben-Moshe, Benjamin A. Levinstein & Jonathan Livengood - 2023 - Theoretical Medicine and Bioethics 44 (6):545-566.
    In this paper, we illustrate some serious difficulties involved in conveying information about uncertain risks and securing informed consent for risky interventions in a clinical setting. We argue that in order to secure informed consent for a medical intervention, physicians often need to do more than report a bare, numerical probability value. When probabilities are given, securing informed consent generally requires communicating how probability expressions are to be interpreted and communicating something about the quality and quantity of the evidence for (...)
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  5. Simulation of Trial Data to Test Speculative Hypotheses about Research Methods.Hamed Tabatabaei Ghomi & Jacob Stegenga - 2023 - In Kristien Hens & Andreas De Block (eds.), Advances in Experimental Philosophy of Medicine. London: Bloomsbury. pp. 111-128.
  6. What evidence for a cholera vaccine? Jaime Ferrán’s submissions to the Prix Bréant.David Teira & Clara Uzcanga - 2023 - Journal of the History of Medicine and Allied Sciences.
    This article analyses how the French Academy of Sciences assessed Jaime Ferrán’s cholera vaccine submitted for the Prix Bréant in the 1880s. Ferrán, a Spanish independent physician, discovered the treatment in 1884 and tried it on thousands of patients during the cholera outbreak in Valencia the following year. His evaluation sparked a controversy in Spain and abroad on the vaccine’s efficacy. The Bréant jury did not see any evidence for it in Ferrán’s submission, a decision usually interpreted in terms of (...)
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  7. Reviewing the Reproduction Number R in Covid-19 Models.Maria Cristina Amoretti & Elisabetta Lalumera - 2022 - Philosophy of Medicine 3 (1).
    Most of the epidemiological models of the Covid-19 pandemic contain the reproduction number as a parameter. In this article we focus on some shortcomings regarding its role in driving health policies and political decisions. First, we summarize what R is and what it is used for. Second, we introduce a three-question matrix for the evaluation of any construct or parameter within a model. We then review the main literature about R to highlight some of its shortcomings and apply to them (...)
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  8. Reductionist methodology and the ambiguity of the categories of race and ethnicity in biomedical research: an exploratory study of recent evidence.Joanna Karolina Malinowska & Tomasz Żuradzki - 2022 - Medicine, Health Care and Philosophy (1):1-14.
    In this article, we analyse how researchers use the categories of race and ethnicity with reference to genetics and genomics. We show that there is still considerable conceptual “messiness” (despite the wide-ranging and popular debate on the subject) when it comes to the use of ethnoracial categories in genetics and genomics that among other things makes it difficult to properly compare and interpret research using ethnoracial categories, as well as draw conclusions from them. Finally, we briefly reconstruct some of the (...)
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  9. Evidence of effectiveness.Jacob Stegenga - 2022 - Studies in History and Philosophy of Science Part A 91 (C):288-295.
    There are two competing views regarding the role of mechanistic knowledge in inferences about the effectiveness of interventions. One view holds that inferences about the effectiveness of interventions should be based only on data from population-level studies (often statistical evidence from randomised trials). The other view holds that such inferences must be based in part on mechanistic evidence. The competing views are local principles of inference, the plausibility of which can be assessed by a more general normative principle of inference. (...)
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  10. Red herrings about relative measures: A response to Hoefer and Krauss.Jacob Stegenga - 2022 - Studies in History and Philosophy of Science Part A 92 (C):56-59.
  11. Philosophy of Advanced medical Imaging.Elisabetta Lalumera & Stefano Fanti - 2021 - Springer International.
    This is the first book to explore the epistemology and ethics of advanced imaging tests, in order to improve the critical understanding of the nature of knowledge they provide and the practical consequences of their utilization in healthcare. Advanced medical imaging tests, such as PET and MRI, have gained center stage in medical research and in patients’ care. They also increasingly raise questions that pertain to philosophy: What is required to be an expert in reading images? How are standards for (...)
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  12. Being Seen by the Doctor: A Meditation on Power, Institutional Racism, and Medical Ethics.Bryan Mukandi - 2021 - Journal of Bioethical Inquiry 18 (1):33-44.
    The following pages sketch the outlines of “a Canaanite reading” of the health system. Beginning with the Black person—African, Afro-diasporic, Aboriginal, and Torres Strait Islander—who is seen by a health professional, the functions and effects of the racializing gaze are examined. I wrestle with Al Saji’s understanding of “colonial disregard,” Whittaker’s insights into the extractive disposition of settler institutions vis-à-vis Indigenous peoples, and Saidiya Hartman and Fred Moten’s struggle with the spectacular. This leads me to conclude that the situation of (...)
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  13. The Quest for System-Theoretical Medicine in the COVID-19 Era.Felix Tretter, Olaf Wolkenhauer, Michael Meyer-Hermann, Johannes W. Dietrich, Sara Green, James Marcum & Wolfram Weckwerth - 2021 - Frontiers in Medicine 8:640974.
    Precision medicine and molecular systems medicine (MSM) are highly utilized and successful approaches to improve understanding, diagnosis, and treatment of many diseases from bench-to-bedside. Especially in the COVID-19 pandemic, molecular techniques and biotechnological innovation have proven to be of utmost importance for rapid developments in disease diagnostics and treatment, including DNA and RNA sequencing technology, treatment with drugs and natural products and vaccine development. The COVID-19 crisis, however, has also demonstrated the need for systemic thinking and transdisciplinarity and the limits (...)
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  14. The case as a travelling genre.Maria Böhmer - 2020 - History of the Human Sciences 33 (3-4):111-128.
    This contribution explores how Forrester’s work on cases has opened up an arena that might be called ‘the medical case as a travelling genre’. Although usually focused on the course of disease in an individual patient and authored mostly by one medical author, medical case histories have a social dimension: Once published, they often circulate in networks of scholars. Moreover, scholars of the history of literature have shown that numerous medical cases seem to travel easily beyond the context of medical (...)
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  15. If p 0, then 1: The impossibility of thinking out cases.Michael J. Flexer - 2020 - History of the Human Sciences 33 (3-4):175-197.
    Forrester’s proposed seventh style of reasoning – thinking in cases – functions as an analogous, dyadic relationship that, whilst indebted philosophically to the logical reasoning and semiotics of Charles Peirce, is prone to creating feedback loops between induction and deduction, precluding novel abductive hypotheses from advancing medical knowledge. Reasoning with a Peircean triadic model opens up the contexts and methods of meaning-making and reasoning through medical cases, and the potent influence of their genre conventions, to intellectual critical scrutiny. Vitally, it (...)
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  16. Medical Nihilism by Jacob Stegenga: What is the right dose? [REVIEW]Jonathan Fuller - 2020 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 81.
  17. A Moral Obligation to Proper Experimentation: Research Ethics as Epistemic Filter in the Aftermath of World War II.Noortje Jacobs - 2020 - Isis 111 (4):759-780.
  18. The limits of conventional justification: inductive risk and industry bias beyond conventionalism.Miguel Ohnesorge - 2020 - Frontiers in Research Metric and Analytics 14.
    This article develops a constructive criticism of methodological conventionalism. Methodological conventionalism asserts that standards of inductive risk ought to be justified in virtue of their ability to facilitate coordination in a research community. On that view, industry bias occurs when conventional methodological standards are violated to foster industry preferences. The underlying account of scientific conventionality, however, is problematically incomplete. Conventions may be justified in virtue of their coordinative functions, but often qualify for posterior empirical criticism as research advances. Accordingly, industry (...)
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  19. COVID-19 and Control: An Essay from a Pragmatic Perspective on Science.Tuomas K. Pernu - 2020 - Multidisciplinary Perspectives on the COVID-19 Pandemic.
    The COVID-19 pandemic has demonstrated how different (even conflicting) interventions on nature can be scientifically justified: interventions can be deemed "effective" only in relation to specific target variables - in relation to variables the values of which we seek to control. Choosing the "right" target variables, in turn, depends on our values and pragmatic aims. This essay is based on a presentation given at the symposium "Multidisciplinary Perspectives on the COVID-19 Pandemic", organised at the Helsinki Collegium for Advanced Studies on (...)
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  20. Moral Normative Force and Clinical Ethics Expertise.Parker Crutchfield - 2019 - American Journal of Bioethics 19 (11):89-91.
    Brummett and Salter propose a useful and timely taxonomy of clinical ethics expertise (2019). As the field becomes further “professionalized” this taxonomy is important, and the core of it is right. It needs some refinement around the edges, however. In their conclusion, Brummett and Salter rightly point out that there is a significant difference between the ethicist whose recommendations are procedure- and process-heavy, consensus-driven, and dialogical and the authoritarian ethicist whose recommendations flow from “private moral views” (Brummett and Salter, 2019). (...)
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  21. Fanti, S., Oyen, W., & Lalumera, E. (2019). Consensus Procedures in Oncological Imaging: The Case of Prostate Cancer.Stefano Fanti, Wim Oyen & Elisabetta Lalumera - 2019 - Cancers 11:1178-1190.
    Recently, there has been increasing interest in methodological aspects of advanced imaging, including the role of guidelines, recommendations, and experts’ consensus, the practice of self-referral, and the risk of diagnostic procedure overuse. In a recent Delphi study of the European Association for Nuclear Medicine (EANM), panelists were asked to give their opinion on 47 scientific questions about imaging in prostate cancer. Nine additional questions exploring the experts’ attitudes and opinions relating to the procedure of consensus building itself were also included. (...)
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  22. Clinical Equipoise and Adaptive Clinical Trials.Nicolas Fillion - 2019 - Topoi 38 (2):457-467.
    Ethically permissible clinical trials must not expose subjects to risks that are unreasonable in relation to anticipated benefits. In the research ethics literature, this moral requirement is typically understood in one of two different ways: as requiring the existence of a state of clinical equipoise, meaning a state of honest, professional disagreement among the community of experts about the preferred treatment; or as requiring an equilibrium between individual and collective ethics. It has been maintained that this second interpretation makes it (...)
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  23. Randomized Controlled Trials for Diagnostic Imaging: Conceptual and Pratical Problems.Elisabetta Lalumera & Stefano Fanti - 2019 - Topoi 38 (2):395-400.
    We raise a problem of applicability of RCTs to validate nuclear diagnostic imaging tests. In spite of the wide application of PET and other similar techniques that use radiopharmaceuticals for diagnostic purposes, RCT-based evidence on their validity is sparse. We claim that this is due to a general conceptual problem that we call Prevalence of Treatment, which arises in connection with designing RCTs for testing any diagnostic procedure in the present context of medical research, and is particularly apparent in this (...)
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  24. An epistemological problem for integration in EBM.Sasha Lawson-Frost - 2019 - Journal of Evaluation in Clinical Practice 25 (6):938-942.
    Evidence-based medicine (EBM) calls for medical practitioners to “integrate” our best available evidence into clinical practice. A significant amount of the literature on EBM takes this integration to be unproblematic, focusing on questions like how to interpret evidence and engage with patient values, rather than critically looking at how these features of EBM can be implemented together. Other authors have also commented on this gap in the literature, for example, identifying the lack of clarity about how patient preferences and evidence (...)
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  25. The Immortal Fly: Eternal Whispers _ Google Scholar.Rituparna Ray Chaudhuri - 2019 - Bloomington,USA: Partridge International In Association with Penguin Random House.
    THE IMMORTAL FLY: ETERNAL WHISPERS. WHO IS SHE? Author: Rituparna Ray Chaudhuri. Hello, Recently my book named, ‘The Immortal Fly: Eternal Whispers : Based On True Events of a Family' been published from Partridge (USA) In Association with Penguin Random House (UK) and achieved a separate Google identity. -/- As being # the author of the book, I thought to define self in the book what is definition of 'Depression'. I wanted to explain self in many ways, but the best (...)
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  26. How (not) to think about theory-change in epidemiology.Dana Tulodziecki - 2019 - Synthese 198 (Suppl 10):2569-2588.
    My purpose in this paper is to show how a re-examination of Snow’s famous South London water study, widely taken to have established that cholera is water-borne, highlights some problems with current, scientific realist accounts of theory-change. When examining scientific controversies, such accounts focus disproportionately on the ‘winning’ theories and their properties, or on those of the reasoning of the scientists who proposed them. I argue that this focus is misguided and leads us to neglect much of what is epistemically (...)
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  27. Ethical and Moral Concerns Regarding Artificial Intelligence in Law and Medicine.Soaad Hossain - 2018 - Journal of Undergraduate Life Sciences 12 (1):10.
    This paper summarizes the seminar AI in Medicine in Context: Hopes? Nightmares? that was held at the Centre for Ethics at the University of Toronto on October 17, 2017, with special guest assistant professor and neurosurgeon Dr. Sunit Das. The paper discusses the key points from Dr. Das' talk. Specifically, it discusses about Dr. Das' perspective on the ethical and moral issues that was experienced from applying artificial intelligence (AI) in law and how such issues can also arise when applying (...)
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  28. Medizin als Wissenschaft - eine wissenschaftstheoretische Analyse.Holger Lyre - 2018 - In Daniela Ringkamp & Héctor Wittwer (eds.), Was ist Medizin? Der Begriff der Medizin und seine ethischen Implikationen. Alber.
    Gegenstand dieses Beitrags ist eine Auseinandersetzung mit der Wissenschaftlichkeit der Medizin. Den Leitfaden der Analyse bildet dabei ein jüngerer Ansatz in der analytischen Wissenschaftstheorie, wonach Systematizität als zentrales Kriterium von Wissenschaft anzusehen ist (Hoyningen-Huene 2013). Ich werde im Detail zeigen, dass die Medizin dieses mehrdimensionale Kriterium insgesamt erfüllt, dass aus der Wissenschaftlichkeit der Medizin aber gleichwohl normative Konsequenzen folgen, die beispielsweise zur Abgrenzung von der Homöopathie und einer kritischen Bewertung des biopsychosozialen Modells führen. Zudem resultieren der Anwendungscharakter der Medizin und (...)
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  29. Medicine without Cure?: A Cluster Analysis of the Nature of Medicine.Thaddeus Metz - 2018 - Journal of Medicine and Philosophy 43 (3):306-312.
    Part of a symposium devoted to ‘Prediction, Understanding, and Medicine’, in which Alex Broadbent argues that the nature of medicine is determined by its competences, i.e., which things it can do well. He argues that, although medicine cannot cure well, it can do a good job of enabling people not only to understand states of the human organism and of what has caused them, but also to predict future states of it. From this Broadbent concludes that medicine is (at least (...)
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  30. Advancing the Philosophy of Medicine: Towards New Topics and Sources.Thaddeus Metz & Chadwin Harris - 2018 - Journal of Medicine and Philosophy 43 (3):281-288.
    The first part of a symposium devoted to Alex Broadbent's essay titled ‘Prediction, Understanding and Medicine’, this article notes the under-development of a variety of issues in the philosophy of medicine that transcend bioethics and the long-standing debates about the nature of health/illness and of evidence-based medicine. It also indicates the importance of drawing on non-Western, and particularly African, traditions in addressing these largely metaphysical and epistemological matters.
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  31. The doctrine of specific etiology.Lauren N. Ross - 2018 - Biology and Philosophy 33 (5-6):37.
    Modern medicine is often said to have originated with nineteenth century germ theory, which attributed diseases to bacterial contagions. The success of this theory is often associated with an underlying principle referred to as the “doctrine of specific etiology”. This doctrine refers to specificity at the level of disease causation or etiology. While the importance of this doctrine is frequently emphasized in the philosophical, historical, and medical literature, these sources lack a clear account of the types of specificity that it (...)
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  32. Twierdzenie Bayesa w projektowaniu strategii diagnostycznych w medycynie.Tomasz Rzepiński - 2018 - Diametros 57:39-60.
    The paper will compare two methods used in the design of diagnostic strategies. The first one is a method that precises predictive value of diagnostic tests. The second one is based on the use of Bayes’ theorem. The main aim of this article is to identify the epistemological assumptions underlying both of these methods. For the purpose of this objective, example projects of one and multi-stage diagnostic strategy developed using both methods will be considered.
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  33. Patient centred diagnosis: sharing diagnostic decisions with patients in clinical practice.Zackary Berger, J. P. Brito, Ns Ospina, S. Kannan, Js Hinson, Ep Hess, H. Haskell, V. M. Montori & D. Newman-Toker - 2017 - British Medical Journal 359:j4218.
    Patient centred diagnosis is best practised through shared decision making; an iterative dialogue between doctor and patient, whichrespects a patient’s needs, values, preferences, and circumstances. -/- Shared decision making for diagnostic situations differs fundamentally from that for treatment decisions. This has important implications when considering its practical application. -/- The nature of dialogue should be tailored to the specific diagnostic decision; scenarios with higher stakes or uncertainty usually require more detailed conversations.
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  34. Pain Research: Where We Are and Why it Matters.Jennifer Corns - 2017 - In The Routledge Handbook of the Philosophy of Pain. Routledge.
  35. The new medical model: a renewed challenge for biomedicine.Jonathan Fuller - 2017 - Canadian Medical Association Journal 189:E640-1.
    Over the past 25 years, several new “medicines” have come screeching onto health care’s various platforms, including narrative medicine, personalized medicine, precision medicine and person-centred medicine. Philosopher Miriam Solomon calls the first three of these movements different “ways of knowing” or “methods,” and argues that they are each a response to shortcomings of methods that came before them. They should also be understood as reactions to the current dominant model of medicine. In this article, I will describe our dominant model, (...)
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  36. The relativity of ‘placebos’: defending a modified version of Grünbaum’s definition.Jeremy Howick - 2017 - Synthese 194 (4):1363-1396.
    Debates about the ethics and effects of placebos and whether ‘placebos’ in clinical trials of complex treatments such as acupuncture are adequate rage. Yet there is currently no widely accepted definition of the ‘placebo’. A definition of the placebo is likely to inform these controversies. Grünbaum’s characterization of placebos and placebo effects has been touted by some authors as the best attempt thus far, but has not won widespread acceptance largely because Grünbaum failed to specify what he means by a (...)
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  37. ‘Cruel to be kind?’ Professionalization, politics and the image of the abstinent psychoanalyst, c. 1940–80.Ulrich Koch - 2017 - History of the Human Sciences 30 (2):88-106.
    This article investigates the changing justifications of one of the hallmarks of orthodox psychoanalytic practice, the neutral and abstinent stance of the psychoanalyst, during the middle decades of the 20th century. To call attention to the shifting rationales behind a supposedly cold, detached style of treatment still today associated with psychoanalysis, explanations of the clinical utility of neutrality and abstinence by ‘classical’ psychoanalysts in the United States are contrasted with how intellectuals and cultural critics understood the significance of psychoanalytic abstinence. (...)
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  38. A Challenge for Evidence-Based Policy.Adam La Caze & Mark Colyvan - 2017 - Axiomathes 27 (1):1-13.
    Evidence-based policy has support in many areas of government and in public affairs more generally. In this paper we outline what evidence-based policy is, then we discuss its strengths and weaknesses. In particular, we argue that it faces a serious challenge to provide a plausible, over-arching account of evidence. We contrast evidence-based policy with evidence-based medicine, especially the role of evidence in assessing the effectiveness of medicines. The evidence required for policy decisions does not easily lend itself to randomized controlled (...)
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  39. Neither from words, nor from visions: understanding p-medicine from innovative treatments.Maël Lemoine - 2017 - Lato Sensu, Revue de la Société de Philosophie des Sciences 4 (2):12-23.
    Despite its vagueness Personalized, Precision, P4, P5, individualized, stratified medicine—or p-medicine in short—has become an increasingly popular term in biomedical literature. Philosophers have attempted to analyze what these various terms involve and have discussed consequences for medical practices. In this article, I argue that an important question remains unaddressed: what has made this project of p-medicine convincing to so many? My argument is that without real achievements, it would never have been. I also make the case that these achievements stem (...)
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  40. Notes on the use of randomised controlled trials to evaluate complex interventions: Community treatment orders as an illustrative case.Feras Ali Mustafa - 2017 - Journal of Evaluation in Clinical Practice 23 (1):185-192.
    Over the past seven decades, randomised controlled trials (RCTs) have revolutionised clinical research and achieved a gold standard status. However, extending their use to evaluate complex interventions is problematic. In this paper we will demonstrate that complex intervention RCTs violate the necessary premises that govern the RCTs logic and underpin their rigour. The lack of blinding, heterogeneity of participants, as well as poor treatment standardisation and difficulty of controlling for confounders, which characterise complex intervention RCTs, can potentially be profoundly detrimental (...)
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  41. ¿Es la medicalización un fenómeno negativo? Un análisis de las consecuencias que suelen atribuirse a la medicalización?Alberto Oya - 2017 - Daimon: Revista Internacional de Filosofía (71):7-18.
    En este artículo expondré un análisis de la valoración negativa de las consecuencias que suelen atribuirse al fenómeno de la medicalización y, partiendo de aquí, mi objetivo básico será mostrar que la medicalización no es en sí mismo un fenómeno negativo. Sólo lo será cuando se obtenga un valor negativo del cálculo entre, por un lado, la efectividad de la propuesta médica para solucionar el problema y, por otro lado, el balance entre los beneficios de dicha propuesta médica y sus (...)
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  42. Handbook of the Philosophy of Medicine.T. Schramme & Steven Edwards (eds.) - 2017 - Springer.
    This is the first wide-ranging, multi-authored handbook in the field of philosophy of medicine, covering the underlying conceptual issues of many important social, political and ethical issues in health care. It introduces and develops over 70 topics, concepts, and issues in the field. It is written by distinguished specialists from multiple disciplines, including philosophy, health sciences, nursing, sociology, political theory, and medicine. Many difficult social and ethical issues in health care are based on conceptual problems, most prominently on the definitions (...)
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  43. Pesticides, Neurodevelopmental Disagreement, and Bradford Hill’s Guidelines.Kristin Shrader-Frechette & Christopher ChoGlueck - 2017 - Accountability in Research 1 (24):30-42.
    Neurodevelopmental disorders such as autism affect one-eighth of all U.S. newborns. Yet scientists, accessing the same data and using Bradford-Hill guidelines, draw different conclusions about the causes of these disorders. They disagree about the pesticide-harm hypothesis, that typical United States prenatal pesticide exposure can cause neurodevelopmental damage. This article aims to discover whether apparent scientific disagreement about this hypothesis might be partly attributable to questionable interpretations of the Bradford-Hill causal guidelines. Key scientists, who claim to employ Bradford-Hill causal guidelines, yet (...)
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  44. Drug Regulation and the Inductive Risk Calculus.Jacob Stegenga - 2017 - In Kevin Elliott & Ted Richards (eds.), Exploring Inductive Risk. New York: Oxford University Press. pp. 17-36.
    Drug regulation is fraught with inductive risk. Regulators must make a prediction about whether or not an experimental pharmaceutical will be effective and relatively safe when used by typical patients, and such predictions are based on a complex, indeterminate, and incomplete evidential basis. Such inductive risk has important practical consequences. If regulators reject an experimental drug when it in fact has a favourable benefit/harm profile, then a valuable intervention is denied to the public and a company’s material interests are needlessly (...)
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  45. Marcum, James A. : The Bloomsbury companion to contemporary philosophy of medicine: Bloomsbury Academic, London, 2017. 424 pp, $172.00 , ISBN: 9781474233002. [REVIEW]Mary Jean Walker - 2017 - Theoretical Medicine and Bioethics 38 (6):501-506.
  46. Reasonableness, Credibility, and Clinical Disagreement.Mary Jean Walker & Wendy A. Rogers - 2017 - AMA Journal of Ethics 19 (2):176-182.
    Evidence in medicine can come from more or less trustworthy sources and be produced by more or less reliable methods, and its interpretation can be disputed. As such, it can be unclear when disagreements in medicine result from different, but reasonable, interpretations of the available evidence and when they result from unreasonable refusals to consider legitimate evidence. In this article, we seek to show how assessments of the relevance and implications of evidence are typically affected by factors beyond that evidence (...)
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  47. Reduction in the Biomedical Sciences.Holly Andersen - 2016 - In Miriam Solomon, Jeremy Simon & Harold Kincaid (eds.), Routledge Companion to Philosophy of Medicine. Routledge.
    This chapter discusses several kinds of reduction that are often found in the biomedical sciences, in contrast to reduction in fields such as physics. This includes reduction as a methodological assumption for how to investigate phenomena like complex diseases, and reduction as a conceptual tool for relating distinct models of the same phenomenon. The case of Parkinson’s disease illustrates a wide variety of ways in which reductionism is an important tool in medicine.
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  48. Evidence based or person centered? An ontological debate.Rani Lill Anjum - 2016 - European Journal for Person Centered Healthcare 4 (2):421-429.
    Evidence based medicine (EBM) is under critical debate, and person centered healthcare (PCH) has been proposed as an improvement. But is PCH offered as a supplement or as a replacement of EBM? Prima facie PCH only concerns the practice of medicine, while the contended features of EBM also include methods and medical model. I here argue that there are good philosophical reasons to see PCH as a radical alternative to the existing medical paradigm of EBM, since the two seem committed (...)
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  49. Evaluating Normative Epistemic Frameworks in Medicine: EBM and Casuistic Medicine.Emily Bingeman - 2016 - Journal of Evaluation in Clinical Practice 22 (4):490-495.
    Since its inception in the early 1990s, evidence-based medicine (EBM) has become the dominant epistemic framework for Western medical practice. However, in light of powerful criticisms against EBM, alternatives such as casuistic medicine have been gaining support in both the medical and philosophical community. In the absence of empirical evidence in support of the claim that EBM improves patient outcomes, and in light of considerations that it is unlikely that such evidence will be forthcoming, another standard is needed to assess (...)
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  50. Henry Knowles Beecher, Jay Katz, and the Transformation of Research with Human Beings.Alexander Morgan Capron - 2016 - Perspectives in Biology and Medicine 59 (1):55-77.
    The modern history of experimentation with human beings is notable for its ethical lacunae. In 1865, in his great work, An Introduction to the Study of Experimental Medicine, Dr. Claude Bernard, the French physician who first established the use of the scientific method in medicine, echoed the earlier injunctions of physician-moralist Moses Maimonides in counseling his fellow physicians not to treat their patients solely as a means of advancing knowledge. Yet such cautions had no apparent effect on the physicians who, (...)
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