Bioethicists have recently expressed concern over a lack of quality control within the field. This apprehension focuses on bioethics expanding in ways that obscure its distinctive ethical remit and the specialist reasoning skills it requires. This thesis about the quality and conduct of bioethics may have particular relevance for clinical ethics. As one of the youngest offshoots of bioethics, the field focuses on the ethical issues that arise specifically in a clinical context. However, non-ethics specialists are increasingly involved in this (...) field. This means that clinical ethics could be especially vulnerable to the quality control concerns articulated within bioethics. The growing public profile of clinical ethics means that concerns over quality in this area warrant specific attention by those concerned with declining standards in bioethics and those working in clinical ethics. (shrink)

Strategies to address misinformation and hesitancy about vaccines, including the fear of needles, and to overcome obstacles to access, such as the refrigeration that some vaccines demand, strongly suggest the need to develop new vaccine delivery technologies. But, given widespread distrust surrounding vaccination, these new technologies must be introduced to the public with the utmost transparency, care, and community involvement. Two emerging technologies, one a skin‐patch vaccine and the other a companion dye and detector, provide excellent examples of greatly improved (...) delivery technologies for which such a careful approach should be developed in order to increase vaccine uptake. Defusing fears and conspiracy mongering must be a key part of their rollout. (shrink)

Incapacitated and surrogateless patients are an ever-growing trend in the world of health care. Although the extent of the issue is unknown, 1 out 20 deaths in the intensive care unit (ICU) occurre...

The new regulations on xenotransplantation pay insufficient attention to the broad ethical problems raised by this technique and that the abandonment of a national body with overall regulatory authority in this area is a mistake.Following reports from the Nuffield Council on Bioethics1 and, most importantly, the Advisory Group on the Ethics of Xenotransplantation2 , the UK Xenotransplantation Interim Regulatory Authority was established in 1997. The existence of a national body to govern xenotransplantation was deemed to be of critical importance by (...) the Kennedy report given the practical and ethical issues associated with xenotransplantation. Indeed, the Kennedy report recommended that ultimately UKXIRA should be placed on a statutory footing.2 The remit of UKXIRA was to advise the Secretary of State on particular applications, gather information on issues such as safety, and assess whether the preconditions identified by the Kennedy report had been met.3In December 2006, UKXIRA was quietly disbanded, and the Department of Health issued a statement of guidance, the terms of which now govern xenotransplantation in the UK. This document superseded procedures that had been in place since 1998, which had placed the overall regulation of applications to conduct xenotransplantation in the hands of UKXIRA and, ultimately, the Secretary of State.4 The revised guidance defines xenotransplantation as being: “… any procedure that involves the transplantation, implantation, or infusion into a human recipient of either live tissues or organs retrieved from animals, or, human body fluids, cells, tissue or organs that have undergone ex vivo contact with live non-human animal cells, tissues or organs.”5 . Given the range and nature of the procedures covered by the guidance, it is surprising, not to say a little worrying, that it is so …. (shrink)

__Creating Safe, Equitable, Engaging Schools_ brings together the collective wisdom of more than thirty experts from a variety of fields to show how school leaders can create communities that support the social, emotional, and academic needs of all students._ It offers an essential guide for making sense of the myriad evidence‐based frameworks, resources, and tools available to create a continuous improvement system. Chapters illustrate how leaders can leverage the power of school-based teams to assess the needs of students in their (...) school and select appropriate interventions across a wide variety of domains, including social and emotional learning, trauma, restorative practices, cultural responsiveness, and student and family engagement. Filled with recommendations gleaned from research and ongoing work in every US state and territory, _Creating Safe, Equitable, Engaging Schools_ is a critical resource for understanding and adopting evidence-based practices and making programmatic decisions to ensure the ideal conditions for learning, growth, and development. (shrink)

The role of Human Research Ethics Committees (HRECs) in health research is well established. Ethics committees have the good of research participants in mind but they must also assess scientific merit including the design and conduct of studies. In this article the authors’ focus is on qualitative research method and the challenge that the National Statement on Ethical Conduct in Human Research (2007) poses for ethics committees when they assess proposals using the methods outlined in the National Statement.We set out (...) a process for judging the standard of qualitative research proposals and propose that qualitative health research can be assessed using a hierarchy designed for evaluating interview studies. We contrast well-designed studies with those that have design flaws in order to focus on the hallmarks of research merit in studies that use qualitative research methods. Finally, we show that our proposal is compatible with the National Statement.Ethics review provides an early opportunity to identify and redesign inadequate studies that will not contribute to our knowledge base. The challenge for members of ethics committees with little experience in qualitative studies is to be able to assess research excellence by assessing research merit in proposals, recognising the special design features of qualitative research methods. (shrink)

The Monographs produced by the International Agency for Research on Cancer (IARC) apply rigorous procedures for the scientific review and evaluation of carcinogenic hazards by independent experts. The Preamble to the IARC Monographs, which outlines these procedures, was updated in 2019, following recommendations of a 2018 expert Advisory Group. This article presents the key features of the updated Preamble, a major milestone that will enable IARC to take advantage of recent scientific and procedural advances made during the 12 years since (...) the last Preamble amendments. The updated Preamble formalizes important developments already being pioneered in the Monographs Programme. These developments were taken forward in a clarified and strengthened process for identifying, reviewing, evaluating and integrating evidence to identify causes of human cancer. The advancements adopted include strengthening of systematic review methodologies; greater emphasis on mechanistic evidence, based on key characteristics of carcinogens; greater consideration of quality and informativeness in the critical evaluation of epidemiological studies, including their exposure assessment methods; improved harmonization of evaluation criteria for the different evidence streams; and a single-step process of integrating evidence on cancer in humans, cancer in experimental animals and mechanisms for reaching overall evaluations. In all, the updated Preamble underpins a stronger and more transparent method for the identification of carcinogenic hazards, the essential first step in cancer prevention. (shrink)

Physical activity, and likely the motivation for it, varies throughout the day. The aim of this investigation was to create a short assessment (CRAVE: Cravings for Rest and Volitional Energy Expenditure) to measure motivation states (wants, desires, urges) for physical activity and sedentary behaviors. Five studies were conducted to develop and evaluate the construct validity and reliability of the scale, with 1,035 participants completing the scale a total of 1,697 times. In Study 1, 402 university students completed a questionnaire inquiring (...) about the want or desire to perform behaviors “at the present moment (right now).” Items related to physical activity (e.g., “move my body”) and sedentary behaviors (e.g., “do nothing active”). An exploratory structural equation model (ESEM) revealed that 10 items should be retained, loading onto two factors (5 each for Move and Rest). In Study 2, an independent sample (n= 444) confirmed these results and found that Move and Rest desires were associated with stage-of-change for exercise behavior. In Study 3, 127 community-residing participants completed the CRAVE at 6-month intervals over two years- two times each session. Across-session interclass correlations (ICC) for Move (ICC = 0.72–0.95) and Rest (ICC = 0.69–0.88) were higher than when they were measured across 24-months (Move: ICC = 0.53; Rest: ICC = 0.49), indicating wants/desires have state-like qualities. In Study 4, a maximal treadmill test was completed by 21 university students. The CRAVE was completed immediately pre and post. Move desires decreased 26% and Rest increased 74%. Changes in Move and Rest desires were moderately associated with changes in perceived physical fatigue and energy. In Study 5, 41 university students sat quietly during a 50-min lecture. They completed the CRAVE at 3 time points. Move increased 19.6% and Rest decreased 16.7%. Small correlations were detected between move and both perceived energy and tiredness, but not calmness or tension. In conclusion, the CRAVE scale has good psychometric properties. These data also support tenets of the WANT model of motivation states for movement and rest (Stults-Kolehmainen et al., 2020a). Future studies need to explore how desires to move/rest relate to dynamic changes in physical activity and sedentarism. (shrink)

From the end of the seventeenth century to now well into the 21st, John Locke’s theory of personal identity has been foundational in the field of philosophy and psychology. Here we suggest that there are two fundamental threads intertwined in Lockean identity, the flux of perception-thought-action (i.e. continuity of consciousness) and memory. Using Maurice Merleau-Ponty, Paul Ricoeur, and Bernard Steigler as guides we will see that these threads constitute a phenomenological self (l’ésprit), a lived experience of our identity that is (...) not only perhaps the most essential component of our humanity, but also the most threatened in today’s ongoing, commercial convergence of the real and the virtual in the “Age of Disruption”. (shrink)

Given a 1-ary sentence operator , we describe L - another 1-ary operator - as as a left inverse of in a given logic if in that logic every formula is provably equivalent to L. Similarly R is a right inverse of if is always provably equivalent to R. We investigate the behaviour of left and right inverses for taken as the operator of various normal modal logics, paying particular attention to the conditions under which these logics are conservatively extended (...) by the addition of such inverses, as well as to the question of when, in such extensions, the inverses behave as normal modal operators in their own right. (shrink)

The main result of this paper is that KT is closed under a cancellation principle. This result extends to KTG1, but it does not extend to modal systems associated with the provability interpretation of L, such as KW and KT4Grz. Following Williamson, these results are applied to philosophical concerns about the proper form for theories of meaning, via the interpretation of L as some kind of veriflability. The cancellation principle can then be read as saying that verifilability conditions and (...) falsiflability conditions jointly determine truth conditions. (shrink)

The paper defends the intelligibility of unrestricted quantification. For any natural number n, 'There are at least n individuals' is logically true, when the quantifier is unrestricted. In response to the objection that such sentences should not count as logically true because existence is contingent, it is argued by consideration of cross-world counting principles that in the relevant sense of 'exist' existence is not contingent. A tentative extension of the upward L?wenheim-Skolem theorem to proper classes is used to argue that (...) a sound and complete axiomatization of the logic of unrestricted universal quantification results from adding all sentences of the form 'There are at least n individuals' as axioms to a standard axiomatization of the first-order predicate calculus. (shrink)

In his book Modal Logic as Metaphysics, Williamson argues that the traditional actualist‐possibilist debate should be abandoned as hopelessly unclear and that we should get on with the clearer contingentism‐necessitism debate. We think that Williamson’s pessimism is not warranted by the brief arguments he gives. In this paper, we explain why and provide a clear formulation of the traditional actualist‐possibilist debate.

An introduction to the special issue on epistemic logic and the foundations of game theory edited by Michael Bacharach and Philippe Mongin. Contributors are Michael Bacharach, Robert Stalnaker, Salvatore Modica and Aldo Rustichini, Luc Lismont and Philippe Mongin, and Hyun-Song Shin and Timothy Williamson.

Timothy Williamson has argued that, unless the speech act of assertion were supposed to be governed by his so-called Knowledge Rule, one could not explain why sentences of the form "A and I do not know that A" are unassertable. This paper advances three objections against that argument, of which the first two aim to show that, even assuming that Williamson's explanandum has been properly circumscribed, his explanation would not be correct, and the third aims to show that (...) his explanandum has not been properly circumscribed. (shrink)

In this paper I shall argue that Tim Williamson’s argument for the anti-luminosity of many mental states faces difficult logical, psychological and epistemological problems. From a logical point of view, his argument is correct. However, the contrary argument that says that the anti-luminosity thesis does not necessarily follow from it is also correct. This opens a sceptical scenario. Hence, if Williamson wants to convince us that we should rationally prefer his argument rather than the other, he needs to (...) add considerations that are not merely logical. These are psychological and epistemological in nature. However, none of these considerations is convincing. (shrink)

ABSTRACT: Many of the results of Timothy Williamson's Knowledge and Its Limits depend upon his argument that many, if not all, of our mental states fail to be luminous in the sense that if we are in them, then we are in a position to know that we are in them. The purpose of this article is to show that his argument is unsound. I conclude by distinguishing between partial and total luminosity, and by arguing that even if mental (...) states are not totally luminous, they are at least partially so.RÉSUMÉ: Plusieurs des résultats du livre de Timothy Williamson, Knowledge and Its Limits dépendent de son argument à l'effet que la plupart, sinon tous nos états mentaux ne sont pas lumineux au sens où tout en se trouvant dans un tel état, nous sommes en position, de savoir que tel est notre état. Cet article a pour objectif de démontrer que ce raisonnement ne tient pas. Nous concluons par une distinction entre luminosité partielle ou complète et soutenons que, même si les états mentaux ne sont pas entièrernent clairvoyants, ils le sont en partie. (shrink)

When I take off my glasses, the world looks blurred. When I put them back on, it looks sharpedged. I do not think that the world really was blurred; I know that what changed was my relation to the distant physical objects ahead, not those objects themselves. I am more inclined to believe that the world really is and was sharp-edged. Is that belief any more reasonable than the belief that the world really is and was blurred? I see more (...) accurately with my glasses on than off, so visual appearances when they are on have some cognitive priority over visual appearances when they are off. If I must choose which kind of visual appearance to take at face value, I will choose the sharp-edged look. But what should I think when I see a mist, which looks very blurred however well I am seeing? Indeed, why choose to take any of the looks at face value? Why not regard all the choices as illegitimate projections of ways of seeing the world onto the world itself? (shrink)

Two opposing tendencies in the philosophy of language go by the names of ‘referentialism’ and ‘inferentialism’ respectively. In the crudest version of the contrast, the referentialist account of meaning gives centre stage to the referential semantics for a language, which is then used to explain the inference rules for the language, perhaps as those which preserve truth on that semantics (since a referential semantics for a language determines the truth-conditions of its sentences). By contrast, the inferentialist account of meaning gives (...) centre stage to the inference rules for the language, which are then used to explain its referential semantics, perhaps as the semantics on which the rules preserve truth. On pain of circularity, we cannot combine both directions of explanation. (shrink)

Timothy Williamson defensa que la filosofia és una ciència teòrica que s’ocupa d’investigar sobre la realitat, d’obtenir coneixement, i que ho fa construint teories, confrontant-les amb l’evidència, d’una manera sistemàtica, disciplinada i socialment organitzada, com les altres ciències. En aquest article es compara aquesta posició, d’una banda, amb la que considera que la filosofia és una reflexió de segon ordre sobre la ciència, la moral, la política, l’art…; i, de l’altra, amb la concepció de la filosofia com a guia (...) de la vida, com a recerca de la saviesa pràctica. (shrink)

Metaphysical modalities are definable from counterfactual conditionals, and the epistemology of the former is a special case of the epistemology of the latter. In particular, the role of conceivability and inconceivability in assessing claims of possibility and impossibility can be explained as a special case of the pervasive role of the imagination in assessing counterfactual conditionals, an account of which is sketched. Thus scepticism about metaphysical modality entails a more far-reaching scepticism about counterfactuals. The account is used to question the (...) significance of the distinction between a priori and a posteriori knowledge. (shrink)

Experiences of embodied remembering are familiar and diverse. We settle bodily into familiar chairs or find our way easily round familiar rooms. We inhabit our own kitchens or cars or workspaces effectively and comfortably, and feel disrupted when our habitual and accustomed objects or technologies change or break or are not available. Hearing a particular song can viscerally bring back either one conversation long ago, or just the urge to dance. Some people explicitly use their bodies to record, store, or (...) cue memories. Others can move skilfully, without stopping to think, in complex and changing environments thanks to the cumulative expertise accrued in their history of fighting fires, or dancing, or playing hockey. The forms of memory involved in these cases may be distinct, operating at different timescales and levels, and by way of different mechanisms and media, but they often cooperate in the many contexts of our practices of remembering. (shrink)

This book brings together in one place the work of one of our most respected economic theorists, on a field in which he has played a large part in originating: the New Institutional Economics. Transaction cost economics, which studies the governance of contractual relations, is the branch of the New Institutional Economics with which Oliver Williamson is especially associated.Transaction cost economics takes issue with one of the fundamental building blocks in microeconomics: the theory of the firm. Whereas orthodox economics (...) describes the firm in technological terms, as a production function, transaction cost economics describes the firm in organizational terms, as a governance structure. Alternative feasible forms of organization--firms, markets, hybrids, bureaus--are examined comparatively. The analytical action resides in the details of transactions and the mechanisms of governance.Transaction cost economics has had a pervasive influence on current economic thought about how and why institutions function as they do, and it has become a practical framework for research in organizations by representatives of a variety of disciplines. Through a transaction cost analysis, The Mechanisms of Governance shows how and why simple contracts give way to complex contracts and internal organization as the hazards of contracting build up. That complicates the study of economic organization, but a richer and more relevant theory of organization is the result. Many testable implications and lessons for public policy accrue to this framework. Applications of both kinds are numerous and growing.Written by one of the leading economic theorists of our time, The Mechanisms of Governance is sure to be an important work for years to come. It will be of interest to scholars and students of economics, organization, management, and law. (shrink)

Being social creatures in a complex world, we do things together. We act jointly. While cooperation, in its broadest sense, can involve merely getting out of each other’s way, or refusing to deceive other people, it is also essential to human nature that it involves more active forms of collaboration and coordination (Tomasello 2009; Sterelny 2012). We collaborate with others in many ordinary activities which, though at times similar to those of other animals, take unique and diverse cultural and psychological (...) forms in human beings. But we also work closely and interactively with each other in more peculiar and flexible practices which are in distinctive ways both species-specific and culturally and historically contingent: from team sports to shared labour, from committee work to mass demonstrations, from dancing to reminiscing together about old times. (shrink)

The need to evaluate the performance of clinical ethics services is widely acknowledged although work in this area is more developed in the United States. In the USA many studies that assess clinical ethics services have utilized empirical methods and assessment criteria. The value of these approaches is thought to rest on their ability to measure the value of services in a demonstrable fashion. However, empirical measures tend to lack ethical content, making their contribution to developments in ethical governance unclear. (...) The steady increase of clinical ethics committees in the UK must be accompanied by efforts to evaluate their performance. As part of this evaluative work it is important to examine how the practice of clinical ethics committees can be informed by empirical measures. (shrink)

It is widely assumed that religion is responsible for dictating and guiding moral behavior. This study investigated that claim and its relationship to monetary incentive, self-esteem, and gender within the context of academic dishonesty. A sample of 65 undergraduate students were assessed using a revision of Allport's Religious Orientation Scale and then monitored for cheating on a computerized version of the Graduate Records Exam under different experimental conditions. Self-esteem and monetary incentive were manipulated, and gender was selected to measure their (...) effect on cheating behavior. Results of this study found that: participants’ religious orientation was not related to their tendency to cheat in any way; participants cheated significantly more when receiving monetary incentive for their performance than when they did not; participants with induced low self-esteem cheated significantly more than those with induced high self-esteem; and men cheated more than women at a level that bordered on significance. Academic performance was not found related to academic cheating. Findings are discussed in the context of existing literature. (shrink)

Kant stated that there are three mental faculties: cognition, feeling, and desire. The faculty of feeling has received the least scholarly attention, despite its importance in Kant's broader thought, and this volume of new essays is the first to present multiple perspectives on a number of important questions about it. Why does Kant come to believe that feeling must be described as a separate faculty? What is the relationship between feeling and cognition, on the one hand, and desire, on the (...) other? What is the nature of feeling? What do the most discussed Kantian feelings, such as respect and sublimity, tell us about the nature of feeling for Kant? And what about other important feelings that have been overlooked or mischaracterized by commentators, such as enthusiasm and hope? This collaborative and authoritative volume will appeal to Kant scholars, historians of philosophy, and those working on topics in ethics, aesthetics, and emotions. (shrink)