The IARC Monographs: Updated procedures for modern and transparent evidence synthesis in cancer hazard identification
Jonathan M. Samet, Weihsueh A. Chiu, Vincent Cogliano, Jennifer Jinot, David Kriebel, Ruth M. Lunn, Frederick A. Beland, Lisa Bero, Patience Browne, Lin Fritschi, Jun Kanno, Dirk W. Lachenmeier, Qing Lan, Gérard Lasfargues, Frank Le Curieux, Susan Peters, Pamela Shubat, Hideko Sone, Mary C. White, Jon Williamson, Marianna Yakubovskaya, Jack Siemiatycki, Paul A. White, Kathryn Z. Guyton, Mary K. Schubauer-Berigan, Amy L. Hall, Yann Grosse, Véronique Bouvard, Lamia Benbrahim-Tallaa, Fatiha El Ghissassi, Béatrice Lauby-Secretan, Bruce Armstrong, Rodolfo Saracci, Jiri Zavadil, Kurt Straif & Christopher P. Wild
AbstractThe Monographs produced by the International Agency for Research on Cancer apply rigorous procedures for the scientific review and evaluation of carcinogenic hazards by independent experts. The Preamble to the IARC Monographs, which outlines these procedures, was updated in 2019, following recommendations of a 2018 expert Advisory Group. This article presents the key features of the updated Preamble, a major milestone that will enable IARC to take advantage of recent scientific and procedural advances made during the 12 years since the last Preamble amendments. The updated Preamble formalizes important developments already being pioneered in the Monographs Programme. These developments were taken forward in a clarified and strengthened process for identifying, reviewing, evaluating and integrating evidence to identify causes of human cancer. The advancements adopted include strengthening of systematic review methodologies; greater emphasis on mechanistic evidence, based on key characteristics of carcinogens; greater consideration of quality and informativeness in the critical evaluation of epidemiological studies, including their exposure assessment methods; improved harmonization of evaluation criteria for the different evidence streams; and a single-step process of integrating evidence on cancer in humans, cancer in experimental animals and mechanisms for reaching overall evaluations. In all, the updated Preamble underpins a stronger and more transparent method for the identification of carcinogenic hazards, the essential first step in cancer prevention.
Similar books and articles
The IARC and Mechanistic Evidence.Bert Leuridan & Erik Weber - 2011 - In Phyllis Illari, Federica Russo & Jon Williamson (eds.), Causality in the Sciences. Oxford University Press. pp. 91--109.
Extrapolation and the Russo–Williamson Thesis.Michael Wilde & Veli-Pekka Parkkinen - 2019 - Synthese 196 (8):3251-3262.
Mentalism and Epistemic Transparency.Declan Smithies - 2012 - Australasian Journal of Philosophy 90 (4):723-741.
A Theory of Evidence for Evidence-Based Policy.Nancy Cartwright & Jacob Stegenga - 2011 - In Philip Dawid, William Twining & Mimi Vasilaki (eds.), Evidence, Inference and Enquiry. Oup/British Academy. pp. 291.
Mechanisms and the Evidence Hierarchy.Brendan Clarke, Donald Gillies, Phyllis Illari, Federica Russo & Jon Williamson - 2014 - Topoi 33 (2):339-360.
The Fate of Darwinism: Evolution After the Modern Synthesis.David J. Depew & Bruce H. Weber - 2011 - Biological Theory 6 (1):89-102.
Vitamin E and the Risk of Prostate Cancer: Updated Results of the Selenium and Vitamin E Cancer Prevention Trial.E. A. Klein, I. Thompson, C. M. Tangen, M. S. Lucia, P. Goodman, L. M. Minasian, L. G. Ford, H. L. Parnes, J. M. Gaziano, D. D. Karp, M. M. Lieber, P. J. Walther, J. K. Parsons, J. Chin, A. K. Darke, S. M. Lippman, G. E. Goodman, F. L. Meyskens & L. H. Baker - unknown
Identification and Targeting of Cancer Stem Cells.Tobias Schatton, Natasha Y. Frank & Markus H. Frank - 2009 - Bioessays 31 (10):1038-1049.
Foreword to Julian Huxley's "Evolution: The Modern Synthesis".Massimo Pigliucci & Gerd Müller - 2010 - In Massimo Pigliucci & Gerd Müller (eds.), Evolution: The Modern Synthesis The Definitive Edition Edition. MIT Press. pp. 1-8.
Evo-Devo and the Structure(s) of Evolutionary Theory: A Different Kind of Challenge.Alan Love - 2017 - In Philippe Huneman & Denis M. Walsh (eds.), Challenging the Modern Synthesis. New York: Oxford University Press. pp. 159-187.
Racial and Ethnic Disparities in Patient-Provider Communication With Breast Cancer Patients: Evidence From 2011 MEPS and Experiences With Cancer Supplement.I. White-Means Shelley & Osmani Ahmad Reshad - 2017 - Inquiry: The Journal of Health Care Organization, Provision, and Financing 54:004695801772710.
Genetic Polymorphism and Cancer Susceptibility: Evidence Concerning Acetyltransferases and Cancer of the Urinary Bladder.David W. Hein - 1988 - Bioessays 9 (6):200-204.
The So-Called Extended Synthesis and Population Genetics.Lindsay R. Craig - 2010 - Biological Theory 5 (2):117-123.
The so-Called Extended Synthesis and Population Genetics.Lindsay R. Craig - 2010 - Biological Theory 5 (2):117-123.
Added to PP
Historical graph of downloads