This is, of course, a philosophical question, but it is one that I hope to undercut in this paper, by directing attention away from it to what I think is the more basic question, what are the conditions of order, whether the latter be something that arises in a mind by reason of its habits of analysis and synthesis, or whether it be something inherent in nature and discovered directly? It is, however, necessary to assume that order can be recognized, (...) whatever its origin, and while there is much evidence to suggest that men can be made more sensitive to order through training, I think it must be admitted that even the untrained can recognize order in many situations. I shall therefore make use of the phrases "intuitive order," and "the intuitive recognition of order," to apply to those cases in which order is recognized without the presence in consciousness of explicit principles of order. In other words, I assume that order reveals itself. If it did not, it would be difficult to understand how principles of order ever came to be recognized, for it is only on analysis of a given order that they come to consciousness. (shrink)

Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

Whitehead's magnum opus is as important as it is difficult. It is the only work in which his metaphysical ideas are stated systematically and completely, and his metaphysics are the heart of his philosophical system as a whole.

Our century has witnessed violence on an unprecedented scale, in wars that have torn deep into the fabric of national and international life. And as we can see in the recent strife in Bosnia, genocide in Rwanda, and the ongoing struggle to control nuclear weaponry, ancient enmities continue to threaten the lives of masses of human beings. As never before, the question is urgent and practical: How can nations--or ethnic groups, or races--after long, bitter struggles, learn to live side by (...) side in peace? In An Ethic for Enemies, Donald W. Shriver, Jr., President Emeritus of Union Theological Seminary, argues that the solution lies in our capacity to forgive. Taking forgiveness out of its traditional exclusive association with personal religion and morality, Shriver urges us to recognize its importance in the secular political arena. The heart of the book examines three powerful and moving cases from recent American history--our postwar dealings with Germany, with Japan, and our continuing domestic problem with race relations--cases in which acts of forgiveness have had important political consequences. Shriver traces how postwar Germany, in its struggle to break with its political past, progressed from denial of a Nazi past, to a formal acknowledgement of the crimes of Nazi Germany, to providing material compensation for survivors of the Holocaust. He also examines the efforts of Japan and the United States, over time and across boundaries of race and culture, to forgive the wrongs committed by both peoples during the Pacific War. And finally he offers a fascinating discussion of the role of forgiveness in the American civil rights movement. He shows, for instance, that even Malcolm X recognized the need to move from contempt for the integrationist ideal to a more conciliatory, repentant stance toward Civil Rights leaders. Malcolm came to see that only through forgiveness could the separate voices of the African-American movement work together to achieve their goals. If mutual forgiveness was a radical thought in 1964, Shriver reminds us that it has yet to be realized in 1994. "We are a long way from ceasing to hold the sins of the ancestors against their living children," he writes. Yet in this poignant volume, we discover how, by forgiving, enemies can progress and have progressed toward peace. A timely antidote to today's political conflicts, An Ethic for Enemies challenges to us to confront the hatreds that cripple society and threaten to destroy the global village. (shrink)

Cognitive neuroscientists have anticipated the union of neural and behavioral science with ethics (Gazzaniga 2005). The identification of an ethical rule—the dictum that we should treat others in the manner in which we would like to be treated—apparently widespread among human societies suggests a dependence on fundamental human brain mechanisms. Now, studies of neural and molecular mechanisms that underlie the feeling of fear suggest how this form of ethical behavior is produced. Counterintuitively, a new theory presented here states that it (...) is actually a loss of social information that leads to sharing others' fears with our own, thus allowing us to treat others as we would like to be treated. Adding to that hypothetical mechanism is the well-studied predilection toward affiliative behaviors. Thus, even as Chomsky hypothesizes that humans are predisposed to utter grammatical sentences, we propose that humans are 'wired for reciprocity'. However, these two neural forces supporting ethical behavior do not explain individual or collective violence. At any given moment, the ability to produce behavior that obeys this ethical rule is proposed to depend on a balance between mechanisms for prosocial and antisocial behaviors. That balance results not only from genetic influences on temperament but also from environmental effects particularly during critical neonatal and pubertal periods. (shrink)

Applying the rules and systems of mathematics and logic to instance ontology, this work argues for the validity and problem-solving capacities of instance ontology, and associates it with a version of the realist position which is named by the author as moderate realism.

The most popular and convincing arguments for the claim that vegetarianism is morally obligatory focus on the extensive, unnecessary harm done to animals and to the environment by raising animals industrially in confinement conditions (factory farming). I outline the strongest versions of these arguments. I grant that it follows from their central premises that purchasing and consuming factoryfarmed meat is immoral. The arguments fail, however, to establish that strict vegetarianism is obligatory because they falsely assume that eating vegetables is the (...) only alternative to eating factory-farmed meat that avoids the harms of factory farming. I show that these arguments not only fail to establish that strict vegetarianism is morally obligatory, but that the very premises of the arguments imply that eating some (non-factory-farmed) meat rather than only vegetables is morally obligatory. Therefore, if the central premises of these usual arguments are true, then strict vegetarianism is immoral. (shrink)

Immanuel Kant was a German philosopher. He is a central figure of modern philosophy, and set the terms by which all subsequent thinkers have had to grapple. He argued that human perception structures natural laws, and that reason is the source of morality. His thought continues to hold a major influence in contemporary thought, especially in fields such as metaphysics, epistemology, ethics, political philosophy, and aesthetics.

An adaptive preference is a preference that is regimented in response to an agent’s set of feasible options. The fabled fox in the sour grapes story undergoes an adaptive preference change. I consider adaptive preferences more broadly, to include adaptive preference formation as well. I argue that many adaptive preferences that other philosophers have cast out as irrational sour-grapes-like preferences are actually fully rational preferences worthy of pursuit. I offer a means of distinguishing rational and worthy adaptive preferences from irrational (...) and unworthy ones. The distinction is based on the agent’s own appraisal of the adaptive preference. (shrink)

There is almost no theoretical discussion of non‐human animal well‐being in the philosophical literature on well‐being. To begin to rectify this, I develop a desire satisfaction theory of well‐being for animals. I contrast this theory with my desire theory of well‐being for humans, according to which a human benefits from satisfying desires for which she can offer reasons. I consider objections. The most important are (1) Eden Lin's claim that the correct theory of well‐being cannot vary across different welfare subjects (...) and (2) his objection against theories of human well‐being that require exercising a sophisticated capacity such as reason giving. (shrink)

One version of the desire satisfaction theory of well-being (i.e., welfare, or what is good for one) holds that only the satisfaction of one's present desires for present states of affairs can affect one's well-being. So if I desire fame today and become famous tomorrow, my well-being is positively affected onlyif tomorrow, when I am famous, I still desire to be famous. Call this the present desire satisfaction theory of well-being. I argue, contrary to this theory, that the satisfaction of (...) past desires that are no longer held does indeed affect one's well-being. The satisfaction of past desires is good for one in that the present satisfaction of past desires positively affects one's past well-being. I argue for this view in stages, starting with the recognition that many of our desires are satisfied not at an instant but over an interval of time, and that it is during this interval of time that our well-being is positively affected. Once we get our foot in the door with some temporal thickness to desire satisfaction and the associated well-being, I argue, the door must open more widely to allow for greater temporal distance between present desire satisfaction and past well-being. I defend my thesis that present satisfaction of past desires increases one's past welfare against objections, including the claim that it involves backward causation and Velleman's claim that the view is highly counterintuitive whether or not it involves backward causation. I argue that some of the objections rely on hedonistic intuitions, intuitions that most desire satisfaction theories of welfare aim to correct. Once properly understood and applied, my counterintuitive and controversial thesis is really quite innocuous. (shrink)

Here Donald Livingston traces this distinction through all of Hume's writings and reveals its relevance for contemporary discussion.

In a well-known paper, Bernard Williams argues that an immortal life would not be worth living, for it would necessarily become boring. I examine the implications for the boredom thesis of three human traits that have received insufficient attention in the literature on Williams’ paper. First, human memory decays, so humans would be entertained and driven by things that they experienced long before but had forgotten. Second, even if memory does not decay to the extent necessary to ward off boredom, (...) once-satisfied desires often return after a sufficient period of time. Eternity would always contain sufficient time for our desires to rejuvenate. Third, even if too many of our desires were satisfied but not yet rejuvenated, we can expect that human ingenuity would continue to invent new pursuits, pastimes, careers, and ways of life that would prevent us from becoming bored as we moved from one to another. Finally, I consider and respond to several objections, including the claims that as much variety as I propose to be put into an eternal life is inconsistent with having one character throughout one’s life and that the sort of character change and memory decay I postulate is inconsistent with personal identity. (shrink)

James's classic article "The Dilemma of Determinism" represents only an early and partial statement on his views of free will and determinism. James's mature position incorporates the arguments of "The Dilemma of Determinism" into a robust theory of free will which at once explains the operations of free effort, and delineates the scope of legitimate psychological explanation. Free will is an issue of fact while being beyond the competence of psychological science.

Although human well-being is a topic of much contemporary philosophical discussion, there has been comparatively little theoretical discussion in philosophy of (nonhuman) animal well-being. Animal welfare science is a well-established scientific discipline that studies animal well-being from an empirical standpoint. This article examines parts of this literature that may be relevant to philosophical treatments of animal well-being and to other philosophical issues. First, I explain the dominant conceptions of well-being in animal welfare science and survey some debates in that literature (...) surrounding these competing conceptions. Second, I explain the empirical methods used to measure animal well-being. Third, I argue for the philosophical relevance of the research in animal welfare science and outline some philosophical issues concerning animal welfare and its science that I claim are worthy of attention by philosophers. (shrink)

Institutional corruption is a normative concept of growing importance that embodies the systemic dependencies and informal practices that distort an institution’s societal mission. An extensive range of studies and lawsuits already documents strategies by which pharmaceutical companies hide, ignore, or misrepresent evidence about new drugs; distort the medical literature; and misrepresent products to prescribing physicians. We focus on the consequences for patients: millions of adverse reactions. After defining institutional corruption, we focus on evidence that it lies behind the epidemic of (...) harms and the paucity of benefits. (shrink)

Over the past 35 years, patients have suffered from a largely hidden epidemic of side effects from drugs that usually have few offsetting benefits. The pharmaceutical industry has corrupted the practice of medicine through its influence over what drugs are developed, how they are tested, and how medical knowledge is created. Since 1906, heavy commercial influence has compromised congressional legislation to protect the public from unsafe drugs. The authorization of user fees in 1992 has turned drug companies into the FDA's (...) prime clients, deepening the regulatory and cultural capture of the agency. Industry has demanded shorter average review times and, with less time to thoroughly review evidence, increased hospitalizations and deaths have resulted. Meeting the needs of the drug companies has taken priority over meeting the needs of patients. Unless this corruption of regulatory intent is reversed, the situation will continue to deteriorate. We offer practical suggestions including: separating the funding of clinical trials from their conduct, analysis, and publication; independent FDA leadership; full public funding for all FDA activities; measures to discourage R&D on drugs with few, if any, new clinical benefits; and the creation of a National Drug Safety Board. (shrink)