Results for 'Chris Gyngell'

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  1. Stocking the Genetic Supermarket: Reproductive Genetic Technologies and Collective Action Problems.Chris Gyngell & Thomas Douglas - 2014 - Bioethics 29 (4):241-250.
    Reproductive genetic technologies allow parents to decide whether their future children will have or lack certain genetic predispositions. A popular model that has been proposed for regulating access to RGTs is the ‘genetic supermarket’. In the genetic supermarket, parents are free to make decisions about which genes to select for their children with little state interference. One possible consequence of the genetic supermarket is that collective action problems will arise: if rational individuals use the genetic supermarket in isolation from one (...)
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  2.  99
    Enhancing the Species: Genetic Engineering Technologies and Human Persistence.Chris Gyngell - 2012 - Philosophy and Technology 25 (4):495-512.
    Many of the existing ethical analyses of genetic engineering technologies (GET) focus on how they can be used to enhance individuals—to improve individual well-being, health and cognition. There is a gap in the current literature about the specific ways enhancement technologies could be used to improve our populations and species, viewed as a whole. In this paper, I explore how GET may be used to enhance the species through improvements in the gene pool. I argue one aspect of the species (...)
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  3.  36
    Cognitive Diversity and Moral Enhancement.Chris Gyngell & Simon Easteal - 2015 - Cambridge Quarterly of Healthcare Ethics 24 (1):66-74.
  4.  56
    The Ethics of Human Life Extension: The Second Argument from Evolution.Chris Gyngell - 2015 - Journal of Medicine and Philosophy 40 (6):696-713.
    One argument that is sometimes made against pursuing radical forms of human life extension is that such interventions will make the species less evolvable, which would be morally undesirable. In this article, I discuss the empirical and evaluative claims of this argument. I argue that radical increases in life expectancy could, in principle, reduce the evolutionary potential of human populations through both biological and cultural mechanisms. I further argue that if life extension did reduce the evolvability of the species, this (...)
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  5.  24
    Valuable and Valueless Diversity.Chris Gyngell - 2015 - American Journal of Bioethics 15 (6):38-39.
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  6. Germline edits: Trust ethics review process.Julian Savulescu, Chris Gyngell & Thomas Douglas - 2015 - Nature 520.
    Summary: Edward Lanphier and colleagues contend that human germline editing is an unethical technology because it could have unpredictable effects on future generations. In our view, such misgivings do not justify their proposed moratorium.
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  7. The Moral Imperative to Continue Gene Editing Research on Human Embryos.Julian Savulescu, Jonathan Pugh, Thomas Douglas & Chris Gyngell - 2015 - Protein Cell 6 (7):476–479.
    The publication of the first study to use gene editing techniques in human embryos (Liang et al., 2015) has drawn outrage from many in the scientific community. The prestigious scientific journals Nature and Science have published commentaries which call for this research to be strongly discouraged or halted all together (Lanphier et al., 2015; Baltimore et al., 2015). We believe this should be questioned. There is a moral imperative to continue this research.
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  8. Section I. Understanding the debate. Reason, emotion, and morality : some cautions for the enhancement project / C. A. J. Coady ; Repugnance as performance error : the role of disgust in bioethical intuitions / Joshua May ; Reasons, reflection, and repugnance / Doug McConnell and Jeanette Kennett ; A natural alliance against a common foe? Opponents of enhancement and the social model of disability / Linda Barclay ; Playing God : What is the problem? / John Weckert ; Conservative and critical morality in debate about reproductive technologies / John McMillan ; Human enhancement : conceptual clarity and moral significance / Chris Gyngell and Michael J. Selgelid ; Human enhancement for whom? [REVIEW]Robert Sparrow - 2016 - In Steve Clarke, Julian Savulescu, C. A. J. Coady, Alberto Giubilini & Sagar Sanyal (eds.), The Ethics of Human Enhancement: Understanding the Debate. Oxford University Press.
     
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  9.  19
    Goldilocks and the two principles. A response to Gyngell et al.Peter Mills - 2019 - Journal of Medical Ethics 45 (8):524-525.
    In their paper Chris Gyngell, Hilary Bowman-Smart and Julian Savulescu offer a careful analysis of the Nuffield Council on Bioethics report, Genome Editing and Human Reproduction: social and ethical issues but they challenge us to go further still.i I want to suggest that, although their analysis is clear and accurate, its rather ‘molecular’ approach neglects the overall arc and orientation of the report. Furthermore, their conclusions about prospective parents’ reproductive obligations lack sensitivity to the proper evaluative context and (...)
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  10. The Ethics of Germline Gene Editing.Gyngell Christopher, Douglas Thomas & Savulescu Julian - 2017 - Journal of Applied Philosophy 34 (4):498-513.
    Germline Gene Editing has enormous potential both as a research tool and a therapeutic intervention. While other types of gene editing are relatively uncontroversial, GGE has been strongly resisted. In this article, we analyse the ethical arguments for and against pursuing GGE by allowing and funding its development. We argue there is a strong case for pursuing GGE for the prevention of disease. We then examine objections that have been raised against pursuing GGE and argue that these fail. We conclude (...)
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  11. Great Minds Think Different: Preserving Cognitive Diversity in an Age of Gene Editing.Jonny Anomaly, Julian Savulescu & Christopher Gyngell - 2020 - Bioethics 34 (1):81-89.
  12.  70
    Moral reasons to edit the human genome: picking up from the Nuffield report.Christopher Gyngell, Hilary Bowman-Smart & Julian Savulescu - 2019 - Journal of Medical Ethics 45 (8):514-523.
    In July 2018, the Nuffield Council of Bioethics released its long-awaited report on heritable genome editing. The Nuffield report was notable for finding that HGE could be morally permissible, even in cases of human enhancement. In this paper, we summarise the findings of the Nuffield Council report, critically examine the guiding principles they endorse and suggest ways in which the guiding principles could be strengthened. While we support the approach taken by the Nuffield Council, we argue that detailed consideration of (...)
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  13. Selecting Against Disability: The Liberal Eugenic Challenge and the Argument from Cognitive Diversity.Christopher Gyngell & Thomas Douglas - 2018 - Journal of Applied Philosophy 35 (2):319-340.
    Selection against embryos that are predisposed to develop disabilities is one of the less controversial uses of embryo selection technologies. Many bio-conservatives argue that while the use of ESTs to select for non-disease-related traits, such as height and eye-colour, should be banned, their use to avoid disease and disability should be permitted. Nevertheless, there remains significant opposition, particularly from the disability rights movement, to the use of ESTs to select against disability. In this article we examine whether and why the (...)
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  14.  22
    Drawing the line on in vitro gametogenesis.Lauren Notini, Christopher Gyngell & Julian Savulescu - 2019 - Bioethics 34 (1):123-134.
    In vitro gametogenesis (IVG) might offer numerous research and clinical benefits. Some potential clinical applications of IVG, such as allowing opposite‐sex couples experiencing infertility to have genetically related children, have attracted support. Others, such as enabling same‐sex reproduction and solo reproduction, have attracted significantly more criticism. In this paper, we examine how different ethical principles might help us to draw lines and distinguish between ethically desirable and undesirable uses of IVG. We discuss the alleged distinction between therapeutic and non‐therapeutic uses (...)
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  15.  19
    Non-Invasive Prenatal Testing for “Non-Medical” Traits: Ensuring Consistency in Ethical Decision-Making.Hilary Bowman-Smart, Christopher Gyngell, Cara Mand, David J. Amor, Martin B. Delatycki & Julian Savulescu - 2021 - American Journal of Bioethics 23 (3):3-20.
    The scope of noninvasive prenatal testing (NIPT) could expand in the future to include detailed analysis of the fetal genome. This will allow for the testing for virtually any trait with a genetic contribution, including “non-medical” traits. Here we discuss the potential use of NIPT for these traits. We outline a scenario which highlights possible inconsistencies with ethical decision-making. We then discuss the case against permitting these uses. The objections include practical problems; increasing inequities; increasing the burden of choice; negative (...)
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  16.  25
    Non-Invasive Prenatal Testing for “Non-Medical” Traits: Ensuring Consistency in Ethical Decision-Making.Hilary Bowman-Smart, Christopher Gyngell, Cara Mand, David J. Amor, Martin B. Delatycki & Julian Savulescu - 2021 - American Journal of Bioethics 23 (3):3-20.
    The scope of noninvasive prenatal testing (NIPT) could expand in the future to include detailed analysis of the fetal genome. This will allow for the testing for virtually any trait with a genetic contribution, including “non-medical” traits. Here we discuss the potential use of NIPT for these traits. We outline a scenario which highlights possible inconsistencies with ethical decision-making. We then discuss the case against permitting these uses. The objections include practical problems; increasing inequities; increasing the burden of choice; negative (...)
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  17. Germline gene editing and the precautionary principle.Julian J. Koplin, Christopher Gyngell & Julian Savulescu - 2019 - Bioethics 34 (1):49-59.
    The precautionary principle aims to influence decision‐making in contexts where some activity poses uncertain but potentially grave threats. This perfectly describes the controversy surrounding germline gene editing. This article considers whether the precautionary principle should influence how we weigh the risks and benefits of human germline interventions, focusing especially on the possible threats to the health of future generations. We distinguish between several existing forms of the precautionary principle, assess their plausibility and consider their implications for the ethics of germline (...)
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  18. The dynamics of vagueness.Chris Barker - 2002 - Linguistics and Philosophy 25 (1):1-36.
  19.  24
    Drugs, genes and screens: The ethics of preventing and treating spinal muscular atrophy.Christopher Gyngell, Zornitza Stark & Julian Savulescu - 2020 - Bioethics 34 (5):493-501.
    Spinal muscular atrophy (SMA) is the most common genetic disease that causes infant mortality. Its treatment and prevention represent the paradigmatic example of the ethical dilemmas of 21st‐century medicine. New therapies (nusinersen and AVXS‐101) hold the promise of being able to treat, but not cure, the condition. Alternatively, genomic analysis could identify carriers, and carriers could be offered in vitro fertilization and preimplantation genetic diagnosis. In the future, gene editing could prevent the condition at the embryonic stage. How should these (...)
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  20.  16
    The Parliamentary Inquiry into Mitochondrial Donation Law Reform (Maeve’s Law) Bill 2021 in Australia: A Qualitative Analysis.Jemima W. Allen, Christopher Gyngell, Julian J. Koplin & Danya F. Vears - 2024 - Journal of Bioethical Inquiry 21 (1):67-80.
    Recently, Australia became the second jurisdiction worldwide to legalize the use of mitochondrial donation technology. The Mitochondrial Donation Law Reform (Maeve’s Law) Bill 2021 allows individuals with a family history of mitochondrial disease to access assisted reproductive techniques that prevent the inheritance of mitochondrial disease. Using inductive content analysis, we assessed submissions sent to the Senate Committee as part of a programme of scientific inquiry and public consultation that informed drafting of the Bill. These submissions discussed a range of bioethical (...)
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  21. Scepticism about Grounding.Chris Daly - 2012 - In Fabrice Correia & Benjamin Schnieder (eds.), Metaphysical Grounding: Understanding the Structure of Reality. Cambridge University Press. pp. 81.
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  22.  93
    Action understanding as inverse planning.Chris L. Baker, Rebecca Saxe & Joshua B. Tenenbaum - 2009 - Cognition 113 (3):329-349.
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  23.  3
    1 Good Parents and New Reproductive Technologies.Christopher Gyngell - 2018 - In Emilian Mihailov, Tenzin Wangmo, Victoria Federiuc & Bernice S. Elger (eds.), Contemporary Debates in Bioethics: European Perspectives. [Berlin]: De Gruyter Open. pp. 1-10.
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  24. Philosophy of Psychedelics.Chris Letheby - 2021 - Oxford, UK: Oxford University Press.
    Recent clinical trials show that psychedelics such as LSD and psilocybin can be given safely in controlled conditions, and can cause lasting psychological benefits with one or two administrations. Supervised psychedelic sessions can reduce symptoms of anxiety, depression, and addiction, and improve well-being in healthy volunteers, for months or even years. But these benefits seem to be mediated by "mystical" experiences of cosmic consciousness, which prompts a philosophical concern: do psychedelics cause psychological benefits by inducing false or implausible beliefs about (...)
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  25. Negotiating Taste.Chris Barker - 2013 - Inquiry: An Interdisciplinary Journal of Philosophy 56 (2-3):240-257.
    Using a vague predicate can make commitments about the appropriate use of that predicate in the remaining part of the discourse. For instance, if I assert that some particular pig is fat, I am committed to judging any fatter pig to be fat as well. We can model this update effect by recognizing that truth depends both on the state of the world and on the state of the discourse: the truth conditions of ‘This pig is fat’ rule out evaluation (...)
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  26.  82
    Promoting Biodiversity.Christopher Gyngell & Julian Savulescu - 2017 - Philosophy and Technology 30 (4):413-426.
    Advances in biotechnology mean that it may soon be possible to recreate previously extinct species. This has led to an emerging debate within bioethics about whether we ought to reintroduce extinct species into our ecosystems. In this paper, we discuss the role that biodiversity could play in this debate. Many believe that biodiversity is a good that should be protected. We argue that if biodiversity is a good, then this suggests it should also be promoted, including by reintroducing previously extinct (...)
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  27.  43
    Ecology and socialism: [solutions to capitalist ecological crisis].Chris Williams - 2010 - Chicago: Haymarket Books.
    A timely, well-grounded analysis that reveals an inconvenient truth: we can't save capitalism and save the planet.
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  28.  26
    Ethics gets in the way: A reply to David Bastow: Chris Gudmunsen.Chris Gudmunsen - 1972 - Religious Studies 8 (4):311-318.
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  29. Justice and Attachment to Natural Resources.Chris Armstrong - 2013 - Journal of Political Philosophy 22 (1):48-65.
  30.  24
    Intrusive images in psychological disorders: Characteristics, neural mechanisms, and treatment implications.Chris R. Brewin, James D. Gregory, Michelle Lipton & Neil Burgess - 2010 - Psychological Review 117 (1):210-232.
  31. Self unbound: ego dissolution in psychedelic experience.Chris Letheby & Philip Gerrans - 2017 - Neuroscience of Consciousness 3:1-11.
    Users of psychedelic drugs often report that their sense of being a self or ‘I’ distinct from the rest of the world has diminished or altogether dissolved. Neuroscientific study of such ‘ego dissolution’ experiences offers a window onto the nature of self-awareness. We argue that ego dissolution is best explained by an account that explains self-awareness as resulting from the integrated functioning of hierarchical predictive models which posit the existence of a stable and unchanging entity to which representations are bound. (...)
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  32. What is Deep Disagreement?Chris Ranalli - 2018 - Topoi 40 (5):983-998.
    What is the nature of deep disagreement? In this paper, I consider two similar albeit seemingly rival answers to this question: the Wittgensteinian theory, according to which deep disagreements are disagreements over hinge propositions, and the fundamental epistemic principle theory, according to which deep disagreements are disagreements over fundamental epistemic principles. I assess these theories against a set of desiderata for a satisfactory theory of deep disagreement, and argue that while the fundamental epistemic principle theory does better than the Wittgensteinian (...)
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  33.  17
    The Donation of Human Biological Material for Brain Organoid Research: The Problems of Consciousness and Consent.Masanori Kataoka, Christopher Gyngell, Julian Savulescu & Tsutomu Sawai - 2024 - Science and Engineering Ethics 30 (1):1-15.
    Human brain organoids are three-dimensional masses of tissues derived from human stem cells that partially recapitulate the characteristics of the human brain. They have promising applications in many fields, from basic research to applied medicine. However, ethical concerns have been raised regarding the use of human brain organoids. These concerns primarily relate to the possibility that brain organoids may become conscious in the future. This possibility is associated with uncertainties about whether and in what sense brain organoids could have consciousness (...)
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  34.  24
    Continuations and Natural Language.Chris Barker & Chung-Chieh Shan - 2014 - Oxford University Press.
    This book takes concepts developed by researchers in theoretical computer science and adapts and applies them to the study of natural language meaning. Summarizing over a decade of research, Chris Barker and Chung-chieh Shan put forward the Continuation Hypothesis: that the meaning of a natural language expression can depend on its own continuation.
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  35.  10
    Shaping children through genetic and environmental means.Christopher Gyngell & Tamara Kayali Browne - forthcoming - Journal of Medical Ethics.
    In ‘Parental Genetic Shaping and Parental Environmental Shaping’, Anca Gheaus argues there is a normative difference between parents using genetic means to influence the development of their child, and parents using environmental means to achieve the same ends. Genetic shaping but not environmental shaping, it is claimed, introduces a negative asymmetry in the child–caregiver relationship. In this paper, we argue that Gheaus’ argument fails as a critique of genetic shaping, and does not establish a moral difference between genetic and environmental (...)
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  36. Fairness, Free-Riding and Rainforest Protection.Chris Armstrong - 2016 - Political Theory 44 (1):106-130.
    If dangerous climate change is to be avoided, it is vital that carbon sinks such as tropical rainforests are protected. But protecting them has costs. These include opportunity costs: the potential economic benefits which those who currently control rainforests have to give up when they are protected. But who should bear those costs? Should countries which happen to have rainforests within their territories sacrifice their own economic development, because of our broader global interests in protecting key carbon sinks? This essay (...)
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  37.  50
    Collective Reflective Equilibrium in Practice (CREP) and controversial novel technologies.Julian Savulescu, Christopher Gyngell & Guy Kahane - 2021 - Bioethics 35 (7):652-663.
    In this paper, we investigate how data about public preferences may be used to inform policy around the use of controversial novel technologies, using public preferences about autonomous vehicles (AVs) as a case study. We first summarize the recent ‘Moral Machine’ study, which generated preference data from millions of people regarding how they think AVs should respond to emergency situations. We argue that while such preferences cannot be used to directly inform policy, they should not be disregarded. We defend an (...)
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  38.  40
    Justice and Natural Resources: An Egalitarian Theory.Chris Armstrong - 2017 - Oxford: Oxford University Press.
    Struggles over precious resources such as oil, water, and land are increasingly evident in the contemporary world. States, indigenous groups, and corporations vie to control access to those resources, and the benefits they provide. These conflicts are rapidly spilling over into new arenas, such as the deep oceans and the Polar regions. How should these precious resources be governed, and how should the benefits and burdens they generate be shared? Justice and Natural Resources provides a systematic theory of natural resource (...)
  39.  5
    Contemporary challenges in children’s health: law, ethics and policy.Michelle Taylor-Sands & Christopher Gyngell - 2021 - Monash Bioethics Review 39 (Suppl 1):1-3.
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  40.  78
    Do States Have the Right to Exclude Immigrations?Chris Bertram - 2018 - Cambridge, UK ; Medford, MA: Polity.
    States claim the right to choose who can come to their country. They put up barriers and expose migrants to deadly journeys. Those who survive are labelled ‘illegal’ and find themselves vulnerable and unrepresented. The international state system advantages the lucky few born in rich countries and locks others into poor and often repressive ones. In this book, Christopher Bertram skilfully weaves a lucid exposition of the debates in political philosophy with original insights to argue that migration controls must be (...)
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  41.  13
    Moving from ‘fully’ to ‘appropriately’ informed consent in genomics: The PROMICE framework.Julian J. Koplin, Christopher Gyngell, Julian Savulescu & Danya F. Vears - 2022 - Bioethics 36 (6):655-665.
    Genomic sequencing technologies (GS) pose novel challenges not seen in older genetic technologies, making traditional standards for fully informed consent difficult or impossible to meet. This is due to factors including the complexity of the test and the broad range of results it may identify. Meaningful informed consent is even more challenging to secure in contexts involving significant time constraints and emotional distress, such as when rapid genomic testing (RGS) is performed in neonatal intensive care units. In this article, we (...)
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  42. Deep disagreement and hinge epistemology.Chris Ranalli - 2018 - Synthese:1-33.
    This paper explores the application of hinge epistemology to deep disagreement. Hinge epistemology holds that there is a class of commitments—hinge commitments—which play a fundamental role in the structure of belief and rational evaluation: they are the most basic general ‘presuppositions’ of our world views which make it possible for us to evaluate certain beliefs or doubts as rational. Deep disagreements seem to crucially involve disagreements over such fundamental commitments. In this paper, I consider pessimism about deep disagreement, the thesis (...)
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  43.  76
    An Introduction to Philosophical Methods.Chris Daly - 2010 - Peterborough, CA: Broadview Press.
    An Introduction to Philosophical Methods is the first book to survey the various methods that philosophers use to support their views. Rigorous yet accessible, the book introduces and illustrates the methodological considerations that are involved in current philosophical debates. Where there is controversy, the book presents the case for each side, but highlights where the key difficulties with them lie. While eminently student-friendly, the book makes an important contribution to the debate regarding the acceptability of the various philosophical methods, and (...)
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  44.  55
    Deep disagreement and hinge epistemology.Chris Ranalli - 2020 - Synthese 197 (11):4975-5007.
    This paper explores the application of hinge epistemology to deep disagreement. Hinge epistemology holds that there is a class of commitments—hinge commitments—which play a fundamental role in the structure of belief and rational evaluation: they are the most basic general ‘presuppositions’ of our world views which make it possible for us to evaluate certain beliefs or doubts as rational. Deep disagreements seem to crucially involve disagreements over such fundamental commitments. In this paper, I consider pessimism about deep disagreement, the thesis (...)
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  45. So where's the explanation?Chris Daly - 2005 - In Helen Beebee & Julian Dodd (eds.), Truthmakers: The Contemporary Debate. Clarendon Press. pp. 85.
  46.  15
    Doing ethics in media: theories and practical applications.Chris Roberts - 2022 - New York, NY: Routledge. Edited by Jay Black.
    The second edition of Doing Ethics in Media continues its mission of providing an accessible but comprehensive introduction to media ethics, with a theoretical grounding in moral philosophy, to help students think clearly and systematically about dilemmas in the rapidly changing media environment. Each chapter highlights specific considerations, cases, and practical applications for the fields of journalism, advertising, digital media, entertainment, public relations, and social media. Six fundamental decision-making questions - the "5Ws and H" around which the book is organized (...)
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  47.  62
    Deep Disagreement (Part 1): Theories of Deep Disagreement.Chris Ranalli & Thirza Lagewaard - 2022 - Philosophy Compass 17 (12):e12886.
    Some disagreements concern our most fundamental beliefs, principles, values, or worldviews, such as those about the existence of God, society and politics, or the trustworthiness of science. These are ‘deep disagreements’. But what exactly are deep disagreements? This paper critically overviews theories of deep disagreement. It does three things. First, it explains the differences between deep and other kinds of disagreement, including peer, persistent, and widespread disagreement. Second, it critically overviews two mainstream theories of deep disagreement, the Wittgensteinian account and (...)
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  48.  18
    Subsidizing PGD: The Moral Case for Funding Genetic Selection.James M. Kemper, Christopher Gyngell & Julian Savulescu - 2019 - Journal of Bioethical Inquiry 16 (3):405-414.
    Preimplantation genetic diagnosis allows the detection of genetic abnormalities in embryos produced through in vitro fertilization. Current funding models in Australia provide governmental subsidies for couples undergoing IVF, but do not extend to PGD. There are strong reasons for publicly funding PGD that follow from the moral principles of autonomy, beneficence and justice for both parents and children. We examine the objections to our proposal, specifically concerns regarding designer babies and the harm of disabled individuals, and show why these are (...)
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  49.  30
    A dual representation theory of posttraumatic stress disorder.Chris R. Brewin, Tim Dalgleish & Stephen Joseph - 1996 - Psychological Review 103 (4):670-686.
  50. Are Ableist Insults Secretly Slurs?Chris Cousens - 2020 - Language Sciences 77.
    Philosophers often treat racist and sexist slurs as a special sort of puzzle. What is the difference between a slur and its correlates? In attempting to answer this question, a second distinction has been overlooked: that between slurs and insults. What makes a term count as a slur? This is not an unnecessary taxonomical question as long as ableist terms such as ‘moron’ are dismissed as mere insults. Attempts to resolve the insult/slur distinction by considering the communicative content of slurs (...)
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