Genetics

Edited by Yafeng Shan (Hong Kong University of Science and Technology)
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  1. Glass ceilings in bacterial genetics.Thomas Bonnin - 2024 - Metascience 33 (1):77-80.
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  2. Origin’s Chapter II: Darwin’s Ideas on Variation Under the Lens of Current Evolutionary Genetics.Roberto Rozenberg - 2023 - In Maria Elice Brzezinski Prestes (ed.), Understanding Evolution in Darwin's “Origin”: The Emerging Context of Evolutionary Thinking. Springer. pp. 221-236.
    The “long argument” presented in the opening chapter of On the Origin of Species develops steadily. Darwin’s comparison between variation under domestication (Chapter I) and variation under nature (Chapter II) is an argument that approximates artificial and natural selection, rendering the second more intelligible. However, questions remain about whether Darwin conceived the analogy before developing the theory of natural selection or whether its use later fulfilled a didactic strategy. Despite not being part of the book, Darwin’s theory of inheritance, Pangenesis, (...)
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  3. Correction to: Richard Lewontin and Theodosius Dobzhansky: Genetics, Race, and the Anxiety of Influence.David Depew - forthcoming - Biological Theory:1-1.
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  4. Specificity as a Guide for the Safe Use of Human Germline Gene Editing—A Response to Sarkar’s Cut and Paste Genetics.Janella Baxter - 2023 - In Michael Boylan (ed.), International Public Health Policy and Ethics. Springer Verlag. pp. 349-354.
    For human germline gene editing to be a viable technique for preventing disease, it must meet a baseline level of safety. This commentary unpacks Sahotra Sarkar’s concept of specificity outlined in Cut and Paste Genetics, which he proposes as a guide for when human germline gene editing can be performed safely. The commentary raises conceptual questions to how specificity is intended to work and raises further epistemic questions for how evidenceEvidence meets the demands of specificity.
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  5. Cut-and-Paste Genetics: A Response to Newman and Baxter.Sahotra Sarkar - 2023 - In Michael Boylan (ed.), International Public Health Policy and Ethics. Springer Verlag. pp. 369-376.
    Newman objects to human germ-line editingGerm-line editing on both philosophical and practical grounds. While the philosophical grounds are compelling, I argue that they are not sufficiently strong to exclude all germ-line editingGerm-line editing to eliminate genetic diseasesGenetic disease. However, the practical reasons he offers preclude germ-line editing except in very limited circumstances. I argue that my requirement of gene specificityGene specificity in Cut-and-Paste Genetics can address his concerns. Meanwhile Baxter argues that my criteria are so restrictive that they would exclude (...)
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  6. CRISPR and Cut-and-Paste Genetics: A Summary.Sahotra Sarkar - 2023 - In Michael Boylan (ed.), International Public Health Policy and Ethics. Springer Verlag. pp. 341-347.
    In 1990 the Human Genome Project (HGP) was initiated with much fanfare as biology’s new Big Science project.
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  7. Richard Lewontin and Theodosius Dobzhansky: Genetics, Race, and the Anxiety of Influence.David Depew - forthcoming - Biological Theory:1-17.
    I reconstruct the relationship between the evolutionary geneticists Theodosius Dobzhansky (1900–1975) and Richard Lewontin (1929–2021). Using archival research and published texts, I show that Lewontin inherited his dissertation director’s research program as well as his “biology of democracy.” He did so in circumstances in which the molecular revolution in genetics was threatening both Dobzhansky’s science and his anti-racist social ideals. Lewontin’s sometimes rocky relationship with the person he called “my professor” sprang from his perception that Dobzhansky was not up to (...)
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  8. A Sexless Universe: How Microbial Genetics Shaped the First History of Reproduction, François Jacob’s The Logic of Life.Nick Hopwood - 2023 - Hopos: The Journal of the International Society for the History of Philosophy of Science 13 (2):511-534.
    Although it has not been much noticed, reproduction is the central theme of François Jacob’s important history of biology, La logique du vivant (The Logic of Life). In a book ostensibly devoted to heredity, this molecular biologist had reproduction integrate levels of organization from organisms to molecules and play a major role in each historical transition between them, not just in the influential argument for a shift “from generation to reproduction.” Moreover, I claim, La logique was the first general history (...)
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  9. Misbehaving science: controversy and the development of behavior genetics.Mariana Craciun - 2017 - New Genetics and Society 36 (1):91-93.
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  10. Part of my story. The meaning and experiences of genes and genetics for sperm donor-conceived offspring.Astrid Indekeu & Kristien Hens - 2019 - New Genetics and Society 38 (1):18-37.
    Existing empirical research often do not explain which concepts about genetics underlie the assumption that genetic information is deemed important for donor-conceived offspring. This study focused on how donor-conceived individuals following anonymous sperm donation give meaning to and make sense of genes and genetics. Analysis is based on focus groups and interviews with adult donor-conceived offspring. Findings suggest that genes are part of their specific context of being donor-conceived but also play a role in daily life. Genes make sense on (...)
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  11. The gene: from genetics to postgenomics.Michelle Lynne LaBonte - 2019 - New Genetics and Society 38 (2):246-247.
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  12. Model behavior: animal experiments, complexity and the genetics of psychiatric disorders.Reuben Message - 2019 - New Genetics and Society 38 (2):243-246.
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  13. Governing anticipatory technology practices. Forensic DNA phenotyping and the forensic genetics community in Europe.Matthias Wienroth - 2018 - New Genetics and Society 37 (2):137-152.
    Forensic geneticists have attempted to make the case for continued investment in forensic genetics research, despite its seemingly consolidated evidentiary role in criminal justice, by shifting the focus to technologies that can provide intelligence. Forensic DNA phenotyping (FDP) is one such emerging set of techniques, promising to infer external appearance and ancestry of an unknown person. On this example, I consider the repertoire of anticipatory practices deployed by scientists, expanding the concept to not only focus on promissory but also include (...)
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  14. Dimensions of responsibility in medical genetics: exploring the complexity of the “duty to recontact”.Shane Doheny, Angus Clarke, Daniele Carrieri, Sandi Dheensa, Naomi Hawkins, Anneke Lucassen, Peter Turnpenny & Susan Kelly - 2018 - New Genetics and Society 37 (3):187-206.
    Discussion of a “duty to recontact” emerged as technological advances left professionals considering getting back in touch with patients they had seen in the past. While there has been much discussion of the duty to recontact as a matter of theory and ethics, there has been rather little empirically based analysis of what this “duty” consists of. Drawing on interviews with 34 professionals working in, or closely with, genetics services, this paper explores what the “duty to recontact” means for healthcare (...)
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  15. Mapping humanity: how modern genetics is changing criminal justice, personalized medicine, and our identities: by Joshua Z. Rappoport, Dallas, BenBella Books Inc., 2020, 300 pp., $USD 17.95, ISBN 978-1-950665-08-2. [REVIEW]Daniel Chavez-Yenter - 2021 - New Genetics and Society 40 (4):624-628.
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  16. “It didn’t mean anything” – moving within a landscape of knowledge to interpret genetics and genetic test results within familial cancer concerns.Mavis Machirori, Christine Patch & Alison Metcalfe - 2021 - New Genetics and Society 40 (4):570-598.
    Genetics is increasingly defining how we understand health and disease, affecting for some, their understanding of inherited disease, and the meaning of medical genetic information. When interpretations of hereditary conditions are determined, partly, by one’s familial experience of heritable characteristics and partly by various other lived experiences, the meaning of genetics becomes highly personal. Through descriptions of stocks of knowledge, this paper describes findings from a qualitative study with a cohort of Black and Asian women with family and personal histories (...)
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  17. Mobilizing mutations: human genetics in the age of patient advocacy: by Daniel Navon, Chicago, University of Chicago Press, 2019, 384 pp., $40.00 (Cloth) $10.00 to $40.00 (E-book), ISBN: 9780226638096. [REVIEW]Aviad E. Raz - 2020 - New Genetics and Society 39 (4):504-507.
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  18. Psychiatric genetics: from hereditary madness to big biology: by Michael Arribas-Ayllon, Andrew Bartlett, and Jamie Lewis, London, Routledge, 2019, 234 pp, $124.00 (Hardback), ISB-978-1-13-899998-5. [REVIEW]Michael Halpin - 2020 - New Genetics and Society 39 (4):502-504.
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  19. JBS Haldane on Infectious Diseases and Genetics.Joshua Lederberg - 1999 - Genetics 153.
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  20. Shallow versus deep genetic causes.Adam C. Smith & Stephen M. Downes - 2023 - Behavioral and Brain Sciences 46:e201.
    We argue that Madole & Harden's distinction between shallow versus deep genetic causes can bring some clarity to causal claims arising from genome-wide association studies (GWASs). However, the authors argue that GWAS only finds shallow genetic causes, making GWAS commensurate with the environmental studies they hope to supplant. We also assess whether their distinction applies best to explanations or causes.
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  21. The ethical and legal duties of physicians in clinical genetics and genomics.Adrian Thorogood & Bartha Maria Knoppers - 2014 - In Yann Joly & Bartha Maria Knoppers (eds.), Routledge Handbook of Medical Law and Ethics. Routledge.
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  22. Questions of method : the philosophy and practice of modern human genetics.Chitra Kannabiran - 2022 - In Gita Chadha & Renny Thomas (eds.), Mapping scientific method: disciplinary narrations. Routledge.
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  23. Why the Anti-reductionist Consensus Won’t Survive the Case of Classical Mendelian Genetics.C. Kenneth Waters - 1990 - PSA Proceedings of the Biennial Meeting of the Philosophy of Science Association 1990 (1):125-139.
    Philosophers now treat the relationship between Classical Mendelian Genetics and molecular biology as a paradigm of nonreduction and this example is playing an increasingly prominent role in debates about the reducibility of theories ranging from macrosocial science to folk psychology. Patricia Churchland (1986), for example, draws an analogy between the alleged elimination of the “causal mainstay” of classical genetics and her view that today’s psychological theory will be eliminated by neuroscience. Patricia Kitcher takes an autonomous rather than eliminativist view of (...)
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  24. Plea for a Collective Genetics.Grégory Cormann & John H. Gillespie - 2023 - Sartre Studies International 29 (1):1-21.
    The study of the early manuscripts of the great authors most often becomes a process of monumentalising or (re)legitimising their work. The recent publication of two of Sartre's early manuscripts – first Empédocle (Empedocles) in 2016 and second, in 2018, his dissertation for his graduate diploma (diplôme d’études supérieures or DES), L'Image dans la vie psychologique (The Image in Psychological Life), both texts written in 1926–1927 – encourages us to propose another type of genetic reading that insists on the collective (...)
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  25. Analysis: OB/gyn-genetics.Melissa Fries - 2016 - Journal of Clinical Ethics 27 (1):59-60.
    Ovarian salvage from a patient with brain death is not available and will not preserve viable ova for future reproduction. Previous interest in assisted reproductive technology is only the first step in this process, which requires careful assessment of maternal risks and potential for recurrent genetic disease.
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  26. Jean Gayon on the History of French Genetics: A Personal View.Richard M. Burian - 2023 - In Pierre-Olivier Méthot (ed.), Philosophy, History and Biology: Essays in Honour of Jean Gayon. Springer Verlag. pp. 281-287.
    This essay highlights some special strengths of Jean Gayon’s approach to theGayon, Jeanon the history of French genetics history of French geneticsFrench geneticsbyGeneticshistory of French genetics providing a partial account of our collaboration. I begin with our first meeting and the work it initiated. I then illustrate key aspects of Jean’s approach to understanding complex histories involving conceptual conflict and conceptual change like those we encountered in our studies of theGayon, Jeanon the history of French genetics history of French geneticsFrench (...)
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  27. Community-level evolutionary processes: Linking community genetics with replicator-interactor theory.Christopher Lean, W. Ford Doolittle & Joseph Bielawski - 2022 - Proceedings of the National Academy of Sciences 119 (46):e2202538119.
    Understanding community-level selection using Lewontin’s criteria requires both community-level inheritance and community-level heritability, and in the discipline of community and ecosystem genetics, these are often conflated. While there are existing studies that show the possibility of both, these studies impose community-level inheritance as a product of the experimental design. For this reason, these experiments provide only weak support for the existence of community-level selection in nature. By contrast, treating communities as interactors (in line with Hull’s replicator-interactor framework or Dawkins’s idea (...)
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  28. 8 Genetics from an Evolutionary Process Perspective.James Griesemer - 2020 - In Eva M. Neumann-Held, Christoph Rehmann-Sutter, Barbara Herrnstein Smith & E. Roy Weintraub (eds.), Genes in Development: Re-reading the Molecular Paradigm. Duke University Press. pp. 199-237.
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  29. 3 From Genes as Determinants to DNA as Resource: Historical Notes on Development and Genetics.Sahotra Sarkar - 2020 - In Eva M. Neumann-Held, Christoph Rehmann-Sutter, Barbara Herrnstein Smith & E. Roy Weintraub (eds.), Genes in Development: Re-reading the Molecular Paradigm. Duke University Press. pp. 77-96.
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  30. 8. From Behavior Genetics to Postgenomics.Aaron Panofsky - 2020 - In Sarah S. Richardson & Hallam Stevens (eds.), Postgenomics: Perspectives on Biology after the Genome. Duke University Press. pp. 150-173.
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  31. Eight Preposterous Propositions: From the Genetics of Homosexuality to the Benefits of Global Warming.Robert Ehrlich - 2003 - Princeton University Press.
    Placebo cures. Global warming. Extraterrestrial life. Psychokinesis. In a time when scientific claims can sound as strange as science fiction--and can have a profound effect on individual life or public policy--assessing the merits of a far-out, supposedly scientific idea can be as difficult as it is urgent. Into the breach between helpless gullibility and unyielding skepticism steps physicist Robert Ehrlich, with an indispensable guide to making sense of "scientific" claims. A series of case studies of some of the most controversial (...)
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  32. Genetics after World War II: The Laboratories at Gif.Richard Burian & Jean Gayon - 1989 - Cahiers Pour l'Histoire du CNRS 6:108-110.
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  33. Free will, determinism, and intuitive judgments about the heritability of behavior.E. A. Willoughby, Alan Love, Matthew McGue, W. G. Iacona, Jack Quigley & James J. Lee - 2019 - Behavior Genetics 49:136-153.
    The fact that genes and environment contribute differentially to variation in human behaviors, traits and attitudes is central to the field of behavior genetics. Perceptions about these differential contributions may affect ideas about human agency. We surveyed two independent samples (N = 301 and N = 740) to assess beliefs about free will, determinism, political orientation, and the relative contribution of genes and environment to 21 human traits. We find that lay estimates of genetic influence on these traits cluster into (...)
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  34. Hume and Kant on utility, freedom, and justice.Paul Guyer - 2022 - In Giovanni Pietro Basile & Ansgar Lyssy (eds.), System and Freedom in Kant and Fichte. Routledge.
  35. Kant's 'as if' and Hume's 'remote analogy' : deism and theism in Prolegomena [sections]57 and 58.Tim Jankowiak - 2021 - In Peter Thielke (ed.), Kant's Prolegomena: A Critical Guide. Cambridge University Press.
  36. Genetics and justice, non-ideal theory and the role of patents : the case of CRISPR-Cas9.Oliver Feeney - 2023 - In Santa Slokenberga, Timo Minssen & Ana Nordberg (eds.), Governing, Protecting, and Regulating the Future of Genome Editing: The Significance of Elspi Perspectives. Brill/Nijhoff.
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  37. Sensational Science, Archaic Hominin Genetics, and Amplified Inductive Risk.Joyce C. Havstad - 2022 - Canadian Journal of Philosophy 52 (3):295-320.
    More than a decade of exacting scientific research involving paleontological fragments and ancient DNA has lately produced a series of pronouncements about a purportedly novel population of archaic hominins dubbed “the Denisova.” The science involved in these matters is both technically stunning and, socially, at times a bit reckless. Here I discuss the responsibilities which scientists incur when they make inductively risky pronouncements about the different relative contributions by Denisovans to genomes of members of apparent subpopulations of current humans. This (...)
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  38. Genetics and the making of Homo sapiens.S. B. Carroll - 2014 - In Francisco José Ayala & John C. Avise (eds.), Essential readings in evolutionary biology. The Johns Hopkins University Press.
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  39. Genetics and dementia : ethical concerns.Caroline J. Huang, Michael Parker & Matthew L. Baum - 2014 - In Charles Foster, Jonathan Herring & Israel Doron (eds.), The law and ethics of dementia. Hart Publishing.
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  40. The genetics of dementia.Sophie Behrman, Klaus P. Ebmeier & Charlotte L. Allan - 2014 - In Charles Foster, Jonathan Herring & Israel Doron (eds.), The law and ethics of dementia. Hart Publishing.
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  41. Creation Ethics: Reproduction, Genetics, and Quality of Life.David DeGrazia - 2012 - , US: Oxford University Press.
    Creation Ethics illuminates an array of issues in "reprogenetics" through the lens of moral philosophy. With novel frameworks for understanding prenatal moral status and human identity, David DeGrazia tackles the ethics of abortion and embryo research, genetic enhancement and prenatal genetic interventions, procreation and parenting, and obligations to future generations.
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  42. Genopolitics : Behavioural Genetics and the End of Politics.Martin G. Weiss - 2016 - In Sergei Prozorov & Simona Rentea (eds.), The Routledge Handbook of Biopolitics. Routledge.
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  43. Some Dark Sides of Interdisciplinarity : The Case of Behavior Genetics.Aaron Panofsky - 2017 - In Scott Frickel, Mathieu Albert & Barbara Prainsack (eds.), Investigating interdisciplinary collaboration: theory and practice across disciplines. Rutgers University Press.
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  44. Reckless or pioneering? Public health genetics services in Israel.Aviad E. Raz - 2018 - In Hagai Boas, Shai Joshua Lavi, Yael Hashiloni-Dolev, Dani Filc & Nadav Davidovitch (eds.), Bioethics and biopolitics in Israel: socio-legal, political and empirical analysis. Cambridge University Press.
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  45. Consuming genetics as a life insurance consumer.Anya E. R. Prince - 2021 - In I. Glenn Cohen, Nita A. Farahany, Henry T. Greely & Carmel Shachar (eds.), Consumer genetic technologies: ethical and legal considerations. Cambridge University Press.
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  46. Moral Judgements and their Actions : A Reflection on the Common Point of View in Hume’s Ethics.Anthony Öhnström - unknown
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  47. Science of genetics and a brief history of its creation. The creation of the laws of heredity.Axadjanova Mohiyat Sadriyevna - unknown
    The article considers the study of science of genetics and a brief history of its creation and the creation of the laws of heredity.
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  48. Spinoza, Hume, and Vasubandhu: the relation between reason and emotion in self-development.Winnie Tomm - unknown
  49. Dynamic Aspects of Human Genetics: Is the Human Germline the Bioethical Key to Human Genetic Engineering?Nicolae Morar - 2022 - American Journal of Bioethics 22 (9):46-49.
    The advent of CRISPR has drastically moved the possibility of genetically modifying human genomes from the space of science fiction into nearby reality. Whether one considers the positive results f...
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  50. Ethical Challenges Associated with Pathogen and Host Genetics in Infectious Disease.Richard Milne & Christine Patch - 2022 - The New Bioethics 29 (1):24-36.
    The Covid-19 pandemic has demonstrated the potential of genomic technologies for the detection and surveillance of infectious diseases. Pathogen genomics is likely to play a major role in the future of research and clinical implementation of genomic technologies. However, unlike human genetics, the specific ethical and social challenges associated with the implementation of infectious disease genomics has received comparatively little attention. In this paper, we contribute to this literature, focusing on the potential consequences for individuals and communities of the use (...)
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