Philosophers have debated whether the advance directives of Alzheimer’s patients should be enforced, even if patients seem content in their demented state. The debate raises deep questions about the nature of human autonomy and personal identity. But it tends to proceed on the assumption that the advance directive’s terms are clear, whereas in practice they are often vague or ambiguous, requiring the patient’s healthcare proxy to make difficult judgment calls. This practical wrinkle raises its own, distinct but related, philosophical question: (...) what criteria may the proxy bring to bear when making such interpretive judgments on which the patient’s life may depend? After defending a general policy of enforcing advance directives on normative (rather than metaphysical) grounds, I argue that when advance directives are vague, a patient’s proxy may permissibly make her own fresh evaluation of the patient’s life as a whole and, in so doing, consider how the patient’s character as a demented person contributes or fails to contribute to that life. (shrink)

Legal philosophers divide over whether it is possible to analyze legal concepts without engaging in normative argument. The influential analysis of legal rights advanced by Jules Coleman and Jody Kraus some years ago serves as a useful case study to consider this issue because even some legal philosophers who are generally skeptical of the neutrality claims of conceptual analysts have concluded that Coleman and Kraus's analysis manages to maintain such neutrality. But that analysis does depend in subtle but important ways (...) on normative claims. Their argument assumes not only a positivist concept of law, but also that it counts in favor of an analysis of legal rights that it increases the number of options available to legal decisionmakers. Thus, whether Coleman and Kraus's analysis is right in the end depends on whether those normative assumptions are justified. If even their analysis, which makes the thinnest of conceptual claims, depends on normative premises, that fact serves as strong evidence of the difficulty of analyzing legal concepts while remaining agnostic on moral and political questions. (shrink)

This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be (...) preserved, reproduced, and made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

With this book, Jacques Barzun pays what he describes as an "intellectual debt" to William James—psychologist, philosopher, and, for Barzun, guide and mentor. Commenting on James's life, thought, and legacy, Barzun leaves us with a wise and civilized distillation of the great thinker's work.

Jacques Barzun's account of William James is a rich-textured and wide-ranging combination of homage, exegesis and personal reflections. In many places it is more Barzun than James; in some it is difficult to tell them apart. Barzun's book is in effect a love offering to a revered master of philosophy, psychology and human relations. He quotes Whitehead's characterization of James as "an adorable genius"; John Jay Chapman's judgment that "I cannot believe that anyone ever met James without (...) feeling that James was a better man than himself"; Santayana's "He was so extremely natural that there was no knowing what his nature was, or what to expect next"; Henry James's description of his brother as "a creature who speaks another language from the rest of mankind, and who would lend charm to a treadmill"; and Charles Peirce's encomium: "Who could be of a nature so different from his than I? He so concrete, so living; I a mere table of contents, so abstract.... Yet in all my life I found scarce a soul who seemed to comprehend naturally... the main spring of my life better than he did. He was even greater in the practice than in the theory of psychology." Barzun tells us that Peirce, jesting in earnest, changed his middle name from Sanders to Santiago in recognition of James's tireless efforts on his behalf over half a lifetime. (shrink)

This anthology brings together material on two major related topics: the military profession, and morality and war. The revised and updated edition retains those sections that made the original version indispensable in the classroom, while incorporating new selections on topics of special concern for the 1980s and beyond. In particular, Colonel Wakin has included essays focusing on the relevance of nuclear deterrence and “just war” theory in the nuclear age. More than a third of the chapters are new.The articles in (...) the first section stress the ethical dimensions of the military profession, considering topics such as the conflict between military values and societal norms, the relation of the military to the state, and the concepts of loyalty, honor, and integrity. New chapters include an essay by Vice Admiral James B. Stockdale suggesting how moral philosophy can serve the profession, contemporary commentaries on the profession by Jacques Barzun and Max Lerner, and new thoughts on ethics and leadership by Colonel Wakin.The essays in Part 2 confront the agonizing moral issues associated with warfare, especially modern warfare. In conjunction with discussions of the laws of war and war crimes, new chapters highlight the continuing debate on nuclear issues. Included are excerpts from the U.S. Catholic Bishops’ pastoral letter, “The Challenge of Peace: God’s Promise and Our Response’’; a defense of pacifism by Stanley Hauerwas; arguments about the use of nuclear weapons and nuclear deterrence by Michael Walzer, Michael Novak, and Charles Krauthammer; and some moral reflections on the Strategic Defense Initiative (“Star Wars’’) by Kenneth Kemp. (shrink)

The collapse of historicism was not merely the demise of an academic tradition but signified a shift in the understanding of hermeneutics and metaphysics. Whereas earlier books have explored the rise and dominance of historicism within academic history, this is the first to trace its collapse and to show how it was shaped by larger philosophical and scientific concerns. Charles R. Bambach's lucid account of the demise of historicism within the context of German metaphysics provides a rich new perspective (...) on the development of the young Heidegger's concept of "historicity" and on the origins of postmodern thought. Bambach reconstructs the methodological debates arising from a pervasive sense of crisis among German philosophers in the late nineteenth century. He details the divergent attempts by the Neo-Kantians, Nietzsche, and Dilthey to overcome the limitations of historical relativism. Heidegger's view of "historicity," Bambach shows, radically transforms the problematic of historicism into a discourse concerning the crisis of philosophical modernity. (shrink)

Plato's late dialogues have often been neglected because they lack the literary charm of his earlier masterpieces. Charles Kahn proposes a unified view of these diverse and difficult works, from the Parmenides and Theaetetus to the Sophist and Timaeus, showing how they gradually develop the framework for Plato's late metaphysics and cosmology. The Parmenides, with its attack on the theory of Forms and its baffling series of antinomies, has generally been treated apart from the rest of Plato's late work. (...) Kahn shows that this perplexing dialogue is the curtain-raiser on Plato's last metaphysical enterprise: the step-by-step construction of a wider theory of Being that provides the background for the creation story of the Timaeus. This rich study, the natural successor to Kahn's earlier Plato and the Socratic Dialogue, will interest a wide range of readers in ancient philosophy and science. (shrink)

This volume presents a series of essays published by Charles Kahn over a period of forty years, in which he seeks to explicate the ancient Greek concept of ...

Although for the last 50 years, ethicists dealing with human experimentation have focused primarily on the need to protect individual research subjects and vulnerable groups, biomedical research, especially in genetics, now requires the establishment of standards for the protection of communities. We have developed such a strategy, based on five steps. (i) Identification of community characteristics relevant to the biomedical research setting, (ii) delineation of a typology of different types of communities using these characteristics, (iii) determination of the range of (...) possible community protections, (iv) creation of connections between particular protections and one or more community characteristics necessary for its implementation, and (v) synthesis of community characteristics and possible protections to define protections appropriate for each type of community. Depending on the particular community, consent and consultation, consultation alone, or no added protections may be required for research. (shrink)

The institutional review board is the social-oversight mechanism charged with protecting research subjects. Performing this task competently requires that the IRB scrutinize informed-consent procedures, the balance of risks and potential benefits, and subject-selection procedures in research protocols. Unfortunately, it may be said that IRBs are spending too much time editing informed-consent forms and too little time analyzing the risks and potential benefits posed by research. This time mismanagement is clearly reflected in the research ethics literature. A review of articles published (...) between 1979 and 1990 in IRB: A Review of Human Subjects Research, for example, reveals a large number of articles on informed consent and confidentiality and considerably fewer on the assessment of risks and potential harms, study design, and subject-selection procedures. (shrink)

Proponents of the view that social structures are ontologically distinct from the people in whose actions they are immanent have assumed that structures can stand in causal relations to individual practices. Were causality to be no more than Humean concomitance correlations between structure and practices would be unproblematic. But two prominent advocates of the ontological account of structures, Bhaskar and Giddens, have also espoused a powers theory of causality. According to that theory causation is brought about by the activity of (...) particulars, in the social psychological case, individuals of some sort. Consistence would demand that structure be those individuals. But neither Giddens nor Bhaskar wish to reify structure to the extent that would fit it for a role as a powerful particular. If only human beings can be powerful particulars in these contexts, the only way that structures can be real must be as properties of conversational interactions. Human action is social just in so far as people direct themselves to engage well in joint activities with others. (shrink)

The issue of the protection of communities in clinical research first arose 10 years ago in studies conducted in technologically developing countries by scientists from technologically developed nations. The question was, which ethical standards ought to apply, those of the Western investigators or local standards?

Materialism & Dialectics : Marx -- The Dialectic of the Concrete Concept : Manheim -- Liberating "the Critical" in Critical Theory : Marcuse -- The Linguistic Turn's Evasion of Philosophy : Critical Warrants for Radical Praxis and Pedagogy -- Herbert Marcuse and the New Culture Wars -- Education Against Alienation -- The Labor Theory of Ethics and Commonwealth -- Global Capitalism and Radical Opposition : Herbert Marcuse;s 1974 Paris Lectures -- Critical Education and Political Economy -- Decommodification & Liberation : (...) Commonwealth as Aesthetic Form of Alienation-Free Society -- A Commonwealth Counter-Offensive -- Appendix No. 1: Engaging a Radical Past : Socialist Germans in New York City, 1853 -- Appendix No. 2: Engaging a Radical Past : Anti-Racism in Kansas Free State Struggle, 1854-64. (shrink)

Introduction Comparative psychology can generally be defined as the branch of psychology that studies the similarities and differences in the behavior of organisms. Formal definitions found in textbooks and encyclopedias disagree whether comparative psychologists restrict their work to the study of animals or include the study of human behavior. This paper offers an opinion on the major problem facing comparative psychology today – where we will find the next generation of comparative psychology students. Something must be done before we lose (...) access to an entire generation of psychology undergraduates. It is not enough to say that comparative psychology is being “absorbed” in other academic units such as “integrative biology”, “integrative study of animal behavior”, “evolutionary psychology”, “comparative cognition”, or “animal cognition.” Indeed, many of these topics are not primarily studied in psychology departments, wherein comparative psychology students have traditionally received joint training in the principles of behavior and comparative analysis, as applied to both humans and other animals. Consider, for example, the difference between comparative psychology and comparative cognition. Comparative cognition includes features of comparative psychology, but they are not identical. Comparative cognition represents a very specific theoretical position whose validity is based on certain suppositions such as the belief (by definition) that the internal cogni... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Place and the "Spatial Turn" in Geography and in HistoryCharles W. J. WithersI. IntroductionA few years ago, British Telecom ran a newspaper advertisement in the British press about the benefits—and consequences—of advances in communications technology. Featuring a remote settlement in the north-west Highlands of Scotland, and with the clear implication that such "out-of-the-way places" were now connected to the wider world (as if they had not been before), the (...) advert proclaimed "Geography is History." What the advert signalled to as the "end" of geography in the sense of the social gradients associated with space and distance is what is known, variously, as "time-space convergence" and "time-space distanciation."1 The terms embrace not just the "collapse" of geographical space given technical advances (in travel time and in communications—consequences of what Castells calls "the information age" and "the network society"2), but also the idea that the modern world has become [End Page 637] more homogenized. One place is now much the same as another. Further, given the likelihood of such technical and cultural changes continuing into the future, geographical distinctiveness, evident in the particularity of place, would be a thing of the past: geography would indeed be history. There is, of course, much evidence to the contrary: that, in the face of "globalisation," questions of locality, sense of place and of identity in place matter now more than ever. Even, then, as Francis Fukuyama cautioned against the "death" of liberal democratic politics as The End of History,3 geography—that is, geography understood as questions to do with place, and questions to do with where you are in the world as part of questions about how you are and who you are in the world—has had considerably heightened significance and for some places and people more than others.4These notions of place—as a particular location, and the character or sense of place—are only part of the meanings associated with place in geographical and in historical work. Like space, its regular epistemic dancing partner in geographical ubiquity and metaphysical imprecision, place is a widespread yet complex term. What follows is historiographical in focus and, of necessity, partial in range. I offer a historiographical survey of the term place, principally but not alone within recent work in geography. In more detail, and with reference to one of the strong senses in which place is used, namely that of locale, "the local," or localness, I trace here the connections between place, space, and the idea of the local as evident in recent work in history and in geography, especially within the history and the geography of science. Particular attention is paid in this context to the distinctive features of what we may think of as the "spatial turn" in the history of science by looking at the idea of place and space in recent work in Enlightenment studies. My argument is three-fold. Notions of place and space, much debated by geographers, have been as central a concern for intellectual historians and historians of science as for philosophers and others, but they have been differently expressed. There is, I shall argue, value in looking at these different views in order to understand that whilst place is a commonplace term it is not agreed upon: working with imprecision has been both opportunity and restriction. In relation to work within the history of science and in Enlightenment studies, consideration of the so-called "spatial turn," of place [End Page 638] as social practice and of placing as a process in accounting for the uneven movement of ideas over space and time may help provide some precision and strengthen connections between geography and history.II. Place (In Geography): A Partial HistoriographyPlace is one of the most fundamental concepts in human geography. It is also one of the most problematic.5 Place, or small-scale regional space, features as a subdivision within the Classical tripartite division of cosmography (the earth in relation to other planetary bodies), geography (the earth as a whole) and chorography (parts of the earth or regional geography). So, too, does the distinction between chorography and chronology as... (shrink)

As genetic research increasingly focuses on communities, there have been calls for extending research protections to them. We critically examine guidelines developed to protect aboriginal communities and consider their applicability to other communities. These guidelines are based on a model of researcher-community partnership and span the phases of a research project, from protocol development to publication. The complete list of 23 protections may apply to those few non-aboriginal communities, such as the Amish, that are highly cohesive. Although some protections may (...) be applicable to less-cohesive communities, such as Ashkenazi Jews, analysis suggests substantial problems in extending these guidelines in toto beyond the aboriginal communities for which they were developed. (shrink)

I distinguish between ‘substantival’ and ‘functional’ forms of vitalism in the eighteenth century. Substantival vitalism presupposes the existence of a (substantive) vital force which either plays a causal role in the natural world as studied scientifically, or remains an immaterial, extra-causal entity. Functional vitalism tends to operate ‘post facto’, from the existence of living bodies to the search for explanatory models that will account for their uniquely ‘vital’ properties better than fully mechanistic models can. I discuss representative figures of the (...) Montpellier school (Bordeu, Ménuret, Fouquet) as functional rather than substantival vitalists, and suggest an additional point regarding the reprisal of vitalism(s) in the 20th century, from Driesch to Canguilhem: that in addition to the substantival and functional varieties, we encounter a third species of vitalism, which I term ‘attitudinal’, as it argues for vitalism as a kind of attitude. (shrink)

David Elder-Vass's “For Emergence: refining Archer's account of social structure,” is the latest of a number of papers which together constitute a family quarrel in the cognitive space After Postmodernism among realist social scientists. In the case under examination here in “Elder-Vass's Move and Giddens's Call”, the concern is the structure and agency problem in the social sciences. The debate continuing in Elder-Vass's paper represents the proponents of the resurrection of Durkheim's social realism under the auspices of Bhaskar's Transcendental Realism; (...) the debate that continues here as a response to the Elder-Vass paper, opposes the latter's attempt to advance the argument for social realism under the canopy of Harre's Immanental realism. The theme of this response is this: Elder-Vass fails to realize the promise of reconciling social structural realism and social relational realism. (shrink)

Few themes resonate as powerfully in Heidegger as those connected to homecoming, homeland, and Heimat. This emphasis plays out most powerfully in Heidegger's reading of Hölderlin and his turn towards language, art, and poetizing as a way of thinking through the poet's relevance in the epoch of homelessness and the abandonment of the gods. As the first book-length study in English of the Heidegger-Hölderlin relation, Of an Alien Homecoming addresses the tension within Heidegger's work between his disastrous political commitments during (...) the era of National Socialism and his attempts to open a path to a German future nurtured on Hölderlin's ideal of poetic dwelling. Charles Bambach reads this work on Hölderlin from 1934–1948 in conversation with the Black Notebooks and Heidegger's metapolitics, even as he uncovers an ethical dimension within Heidegger that pervades his reading of poetry. Throughout all of these various stages on Heidegger's thought path, Hölderlin remains the poet who poetizes the possibility of finding our lost home amidst the homelessness brought about in the epoch of technological thinking. (shrink)

La Valeur inductive de la relativité est sans conteste l'ouvrage le plus méconnu de toute l'oeuvre «philosophique» de Gaston Bachelard. Au silence presque total, à l'absence de lectures, ne répondent que des interprétations du« premier genre», appuyées sur un certain ouï-dire discursif, mais qui font l'autorité des pseudo-standards. Les positions bachelardiennes sont ici confrontées à La Déduction relativiste d'Émile Meyerson. Le poids de l'analyse portera essentiellement sur un dépl(o)iement du dispositif bachelardien d'induction et de construction. L'appareillage « inductif » doit (...) être pensé sur le modèle électromagnétique, et la position «constructiviste» est toujours liée au travail de synthèse. Enfin, c'est une véritable métaphysique que semble dès lors devoir engendrer cette « pensée des sciences ». (shrink)

In this issue of the Journal of Law, Medicine & Ethics Peter Clark provides a comprehensive and sound ethical analysis of clinical trials examining the treatment of advanced Parkinson's disease with fetal tissue transplantation. These studies raise profound questions about how clinical trials of surgical interventions ought to be conducted. At stake is not only the ethical basis of such trials, but differing views as to the proper role of science in medicine and its limitations.Experience with the broader debate on (...) the ethical permissibility of placebo controls has taught us that the choice of control treatment is an aspect of trial design in which ethical and scientific issues overlap. Accordingly, I will highlight, and perhaps expand upon, three issues raised by Clark: What scientific questions ought clinical trials of surgical interventions ask? How should the ethical analysis of risk for such trials be conceived? And, are surgical patients a vulnerable population? (shrink)

The revelation that data obtained for the US-based National Surgical Adjuvant Breast and Bowel Project (NSABP) from subjects enrolled at Hôpital Saint-Luc in Montreal was falsified has eroded public trust in research. Institutions can educate researchers and help prevent unethical research practices by establishing procedures to monitor research involving human subjects. Research monitoring encompasses four categories of activity: annual reviews of continuing research, monitoring of informed consent, monitoring of adherence to approved protocols and monitoring of the integrity of data. The (...) authors describe characteristics of research projects that may call for monitoring procedures in each category. The form taken by such monitoring depends on the nature of the protocol. Although appropriate research monitoring requires substantial investment of personnel and financial resources, it is required under guidelines regulating research involving human subjects in Canada. Research monitoring is a step forward in re-establishing public confidence in medical research. (shrink)

"In Getting Even, Charles Barton contends that revenge can be a form of justice that is constructive and healing for our society. Our current judiciary system, he explains, denies both victims and the accused an active role in the legal proceedings and resolution of their cases, reducing them to bystanders in what is essentially their own conflict. Barton does not argue for an individual's right to take the law into his own hands, but does show that the courts should (...) recognize the revenge motive as legitimate and rational within the rules of justice."--pub. desc. (shrink)

In this paper, I delineate two major problems facing reliabilist approaches in epistemology. I argue that Alvin Goodman's (1986) position fails to solve either problem. I then suggest an alternative reliabilist approach that ties truth-ratio assessments to particular, well-specified cognitive tasks. I claim that a well-specified cognitive task is an empirical hypothesis about a system that involves the specification of input and output types and nomic correlations (including statistical correlations) that underlie the system's performance. On my approach, one characterizes processes (...) by reference to the system's dispositions across the situations consistent with the task. Characterization is best understood as revealing a strategy or a set of strategies for generating outputs from inputs relying on certain nomic correlations associated with the task. (shrink)

Originally published in 1960, The Edge of Objectivity helped to establish the history of science as a full-fledged academic discipline. In the mid-1950s, a young professor at Princeton named Charles Gillispie began teaching Humanities 304, one of the first undergraduate courses offered anywhere in the world on the history of science. From Galileo's analysis of motion to theories of evolution and relativity, Gillispie introduces key concepts, individuals, and themes. The Edge of Objectivity arose out of this course. It must (...) have been a lively class. The Edge of Objectivity is pointed, opinionated, and selective. Even at six hundred pages, the book is, as the title suggests, an essay. Gillispie is unafraid to rate Mendel higher than Darwin, Maxwell above Faraday. Full of wry turns of phrase, the book effectively captures people and places. And throughout the book, Gillispie pushes an argument. He views science as the progressive development of more objective, detached, mathematical ways of viewing the world, and he orchestrates his characters and ideas around this theme. This edition of Charles Coulston Gillispie's landmark book introduces a new generation of readers to his provocative and enlightening account of the advancement of scientific thought over the course of four centuries. Since the original publication of The Edge of Objectivity, historians of science have focused increasingly on the social context of science rather than its internal dynamics, and they have frequently viewed science more as a threatening instance of power than as an accumulation of knowledge. Nevertheless, Gillispie's book remains a sophisticated, fast-moving, idiosyncratic account of the development of scientific ideas over four hundred years, by one of the founding intellects in the history of science. Featuring a new foreword by Theodore Porter, who places the work in its intellectual context and the development of the field, this edition of The Edge of Objectivity is a monumental work by one of the founding intellects of the history of science. (shrink)

Uses interviews with one hundred twenty-five leading male executives to determine how companies can be managed both profitably and ethically.

The existing EELS literature has usefully identified the scope of ethical issues posed by pharmacogenetic and pharmacogenomic research. The time has come for in-depth examination of particular ethical issues. The involvement of racial and ethnic communities in pharmacogenetic and pharmacogenomic research is contentious precisely because it touches upon the science and politics of studying racial and ethnic difference. To date, the ethics literature has not seriously taken account of the fact that such research impinges upon the interests of communities, and (...) that taking such interests seriously requires that we both protect and empower communities in research. We propose a framework that rests upon the recognition that communities are heterogeneous human associations and differing policies are appropriate for differing communities. Community consent and consultation and community consultation alone are neither appropriate nor required for all pharmacogenetic and pharmacogenomic research. Rather, application of these policy protections must take into account particulars of both planned research and the communities involved. (shrink)

The effort to revise the Declaration of Helsinki and the CIOMS Guidelines has sparked a sometimes vitriolic debate centering on the use of placebo controls.

The Standards of Ethical Conduct for Management Accountants (Statement 1C) promulgated by the National Association of Accountants on June 1, 1983, are described and critiqued in this article. Four major issues related to the issuance of the standards are discussed: (1) What are the basic requirements of any ethical system? Does Statement IC meet these requirements? (2) Should a professional be ethical? (3) If ethical behavior is desirable for management accountants, should such standards be formally expressed in writing? (4) If (...) the standards are expressed in writing, what format should be adopted for the content and how should the standards be expressed? (shrink)

In selected texts by Diderot, including the Encyclopédie article “Cabinet d’histoire naturelle” (along with his comments in the article “Histoire nat-urelle”), the Pensées sur l’interprétation de la nature and the Salon de 1767, I examine the interplay between philosophical naturalism and the recognition of the irreducible nature of artifice, in order to arrive at a provisional definition of Diderot’s vision of Nature as “une femme qui aime à se travestir.” How can a metaphysics in which the concept of Nature has (...) a normative status, also ultimately consider it to be something necessarily artificial? Historically, the answer to this question involves the project of natural history. A present-day reconstruction would have to make sense of this project and relate it to the vision of Nature expressed in Diderot’s phrase. In addition, it would hopefully pinpoint the difference between this brand of Enlightenment naturalism and contemporary naturalism, and by extension, allow us to understand a bit more about what naturalism is in general. (shrink)

There is a familiar opposition between a ‘Scientific Revolution’ ethos and practice of experimentation, including experimentation on life, and a ‘vitalist’ reaction to this outlook. The former is often allied with different forms of mechanism – if all of Nature obeys mechanical laws, including living bodies, ‘iatromechanism’ should encounter no obstructions in investigating the particularities of animal-machines – or with more chimiatric theories of life and matter, as in the ‘Oxford Physiologists’. The latter reaction also comes in different, perhaps irreducibly (...) heterogeneous forms, ranging from metaphysical and ethical objections to the destruction of life, as in Margaret Cavendish, to more epistemological objections against the usage of instruments, the ‘anatomical’ outlook and experimentation, e.g. in Locke and Sydenham. But I will mainly focus on a third anti-interventionist argument, which I call ‘vitalist’ since it is often articulated in the writings of the so-called Montpellier Vitalists, including their medical articles for the Encyclopédie. The vitalist argument against experimentation on life is subtly different from the metaphysical, ethical and epistemological arguments, although at times it may borrow from any of them. It expresses a Hippocratic sensibility – understood as an artifact of early modernity, not as some atemporal trait of medical thought – in which Life resists the experimenter, or conversely, for the experimenter to grasp something about Life, it will have to be without torturing or radically intervening in it. I suggest that this view does not have to imply that Nature is something mysterious or sacred; nor does the vitalist have to attack experimentation on life in the name of some ‘vital force’ – which makes it less surprising to find a vivisectionist like Claude Bernard sounding so close to the vitalists. (shrink)

Earlier in the pages of this journal (p 481), Wendler and Miller offered the "net risks test" as an alternative approach to the ethical analysis of benefits and harms in research. They have been vocal critics of the dominant view of benefit-harm analysis in research ethics, which encompasses core concepts of duty of care, clinical equipoise and component analysis. They had been challenged to come up with a viable alternative to component analysis which meets five criteria. The alternative must (1) (...) protect research subjects; (2) allow clinical research to proceed; (3) explain how physicians may offer trial enrolment to their patients; (4) address the challenges posed by research containing a mixture of interventions and (5) define ethical standards according to which the risks and potential benefits of research may be consistently evaluated. This response argues that the net risks test meets none of these criteria and concludes that it is not a viable alternative to component analysis. (shrink)

This paper examines the nomic covariationist strategy of using idealization to define representation. While the literature has focused upon the possibility of defining ideal conditions for perception, I argue that nomic covariationist appeals to idealization are pseudoscientific and contrary to a foundational and empirically well-supported methodological presupposition in cognitive science. Moreover, one major figure in this camp fails to come to grips with its role and its problems in mainstream science. Thus he forwards a false dichotomy of the sciences and (...) treats idealization as a blank check written by scientists on an unknown bank. Finally, I consider and reject alternative formulations of the nomic covariationist's idealization strategy. (shrink)

The category of« organism » has an ambiguous status: scientific or philosophical? In any case, it has long served as a kind of scientific « bolstering » for a philosophical train of argument which seeks to refute the « mechanistic » or « reductionist » trend, which is seen as dominant since the 17th century, whether in the case of Stahlian animism, Leibnizian monadology, the neo-vitalism of Hans Driesch, or, lastly, of the « phenomenology of organic life » in the (...) 20th century, with authors such as Goldstein, Straws, and Weizsäcker, whose influence on Merleau-Ponty but also Canguilhem is obvious. The aim of this article is both to bring to light the sedimentation of this category and to give a critical evaluation of it, in other words, to sec in what way it might still be useful once one has eliminated the possibility of any « organicist » excesses. I suggest a notion of organism as an instrumental fiction. (shrink)