There is a familiar opposition between a ‘Scientific Revolution’ ethos and practice of experimentation, including experimentation on life, and a ‘vitalist’ reaction to this outlook. The former is often allied with different forms of mechanism – if all of Nature obeys mechanical laws, including living bodies, ‘iatromechanism’ should encounter no obstructions in investigating the particularities of animal-machines – or with more chimiatric theories of life and matter, as in the ‘Oxford Physiologists’. The latter reaction also comes in different, perhaps irreducibly (...) heterogeneous forms, ranging from metaphysical and ethical objections to the destruction of life, as in Margaret Cavendish, to more epistemological objections against the usage of instruments, the ‘anatomical’ outlook and experimentation, e.g. in Locke and Sydenham. But I will mainly focus on a third anti-interventionist argument, which I call ‘vitalist’ since it is often articulated in the writings of the so-called Montpellier Vitalists, including their medical articles for the Encyclopédie. The vitalist argument against experimentation on life is subtly different from the metaphysical, ethical and epistemological arguments, although at times it may borrow from any of them. It expresses a Hippocratic sensibility – understood as an artifact of early modernity, not as some atemporal trait of medical thought – in which Life resists the experimenter, or conversely, for the experimenter to grasp something about Life, it will have to be without torturing or radically intervening in it. I suggest that this view does not have to imply that Nature is something mysterious or sacred; nor does the vitalist have to attack experimentation on life in the name of some ‘vital force’ – which makes it less surprising to find a vivisectionist like Claude Bernard sounding so close to the vitalists. (shrink)

Vitalism was long viewed as the most grotesque view in biological theory: appeals to a mysterious life-force, Romantic insistence on the autonomy of life, or worse, a metaphysics of an entirely living universe. In the early twentieth century, attempts were made to present a revised, lighter version that was not weighted down by revisionary metaphysics: “organicism”. And mainstream philosophers of science criticized Driesch and Bergson’s “neovitalism” as a too-strong ontological commitment to the existence of certain entities or “forces”, over and (...) above the system of causal relations studied by mechanistic science, rejecting the weaker form, organicism, as well. But there has been some significant scholarly “push-back” against this orthodox attitude, notably pointing to the 18th-century Montpellier vitalists to show that there are different historical forms of vitalism, including how they relate to mainstream scientific practice. Additionally, some trends in recent biology that run counter to genetic reductionism and the informational model of the gene present themselves as organicist. Here, we examine some cases of vitalism in the twentieth century and today, not just as a historical form but as a significant metaphysical and scientific model. We argue for vitalism’s conceptual originality without either reducing it to mainstream models of science or presenting it as an alternate model of science, by focusing on historical forms of vitalism, logical empiricist critiques thereof and the impact of synthetic biology on current theorizing of vitalism. (shrink)

This paper aims at giving an account of the philosophy of norms of Georges Canguilhem in the framework of his philosophical vitalism. According to Canguilhem, vitalism is not a metaphysical or ontological theory, but rather a general attitude or a perspective about life and living beings, both understood employing the axiological concept of ‘normativity’. This notion allows Canguilhem to enlarge the concept of life beyond the field of biological phenomena, encompassing also phenomena of the social world, included technique and scientific (...) knowledge and rationality. Canguilhem’s perspective relocates human activities within a vitalistic conception of life, which redefines the meaning of human reason by putting it in relation to values and norms. (shrink)

Starting with the observation that there exist contradictory claims in the literature about the relationship between vitalism and emergentism—be it one of inclusion or, on the contrary, exclusion–, this paper aims at disentangling the vitalism–emergentism knot. To this purpose, after having described a particular form of emergentism, namely Lloyd Morgan’s emergent evolutionism, I develop a conceptual analysis on the basis of a distinction between varieties of monism and pluralism. This analysis allows me to identify and characterize several forms of vitalism (...) and emergentism, and a subsequent comparison between these forms constitutes the occasion for a clarification of the relationship between both doctrines. (shrink)

This paper takes up some threads of Deleuze’s and Ruyer’s engagement with biology. I begin by laying out the main features of Deleuze’s scheme of morphogenesis, through the lens of his references to embryology. I take Deleuze’s interest in embryology to be guided by the effort to define bodies solely by form-generating factors which are immanent to them. His concept of virtuality, which indicates the creative component of reality, the open field of connections defining a body’s capacities for transformation and (...) interaction, plays a key role in this regard. I then consider two implications: (1) The insistence on morphogenesis displaces the question of life from given biological entities, which preserve themselves and act through regulated cycles, to the myriad of activities that compose and modify them; (2) It also rearticulates the distinction between the living and the nonliving, in that it separates the question of life from that of its emergence from a given material arrangement. In the second part I examine these points with greater reference to Ruyer. After introducing Ruyer’s concepts of functioning and formation, I focus on his account of the continuity between biological and physicochemical forms, following some of his work on the microbiology and ethology of the time. The real difference is not between the living and the nonliving, but between two modes of bonding and composition variously operating on all scales: morphogenetic and statistical. I conclude by assessing the significance of this claim with respect to the traditional distinction between vitalism and mechanism. (shrink)

Physicalism is the thesis that everything is physical. But what does it mean to say that everything is physical? Daniel Stoljar has recently argued that no account of the physical is available which allows for a formulation of physicalism that is both possibly true and deserving of the name. As against this claim, I argue that a version of the via negativa—roughly, the view that the physical is to be characterised in terms of the nonmental—provides just such an account.

In this paper we examine aspects of Canguilhem’s philosophy of biology, concerning the knowledge of life and its consequences on science and vitalism. His concept of life stems from the idea of a living individual, endowed with creative subjectivity and norms, a Kantian view which “disconcerts logic”. In contrast, two different approaches ground naturalistic perspectives to explore the logic of life and the logic of the living individual in the 1970s. Although Canguilhem is closer to the second, there are divergences; (...) for example, unlike them, he does not dismiss vitalism, often referring to it in his work and even at times describing himself as a vitalist. The reason may lie in their different views of science. (shrink)

In biology the term “vitalism” is usually associated with Hans Driesch’s doctrine of the entelechy: entelechies were nonmaterial, bio-specific agents responsible for governing a few peculiar biological phenomena. Since vitalism defined as such violates metaphysical materialism, the received view refutes the doctrine of the entelechy as a metaphysical heresy. But in the early twentieth century, a different, non-metaphysical evaluation of vitalism was endorsed by some biologists and philosophers, which finally led to a logical refutation of the doctrine of the entelechy. (...) In this non-metaphysical evaluation, first, vitalism was not treated as a metaphysical heresy but a legitimate response to the inadequacy of mechanistic explanations in biology. Second, the refutation of vitalism was logically rather than metaphysically supported by contemporary biological knowledge. The entelechy was not a valid concept, because vitalists could neither formulate vital laws, nor offer convincing examples of experimental indeterminism. (shrink)

Vitalism was long viewed as the most grotesque view in biological theory: appeals to a mysterious life-force, Romantic insistence on the autonomy of life, or worse, a metaphysics of an entirely living universe. In the early twentieth century, attempts were made to present a revised, lighter version that was not weighted down by revisionary metaphysics: “organicism”. And mainstream philosophers of science criticized Driesch and Bergson’s “neovitalism” as a too-strong ontological commitment to the existence of certain entities or “forces”, over and (...) above the system of causal relations studied by mechanistic science, rejecting the weaker form, organicism, as well. But there has been some significant scholarly “push-back” against this orthodox attitude, notably pointing to the 18th-century Montpellier vitalists to show that there are different historical forms of vitalism, including how they relate to mainstream scientific practice (Wolfe and Normandin, eds. 2013). Additionally, some trends in recent biology that run counter to genetic reductionism and the informational model of the gene present themselves as organicist (Gilbert and Sarkar 2000, Moreno and Mossio 2015). Here, we examine some cases of vitalism in the twentieth century and today, not just as a historical form but as a significant metaphysical and scientific model. We argue for vitalism’s conceptual originality without either reducing it to mainstream models of science or presenting it as an alternate model of science, by focusing on historical forms of vitalism, logical empiricist critiques thereof and the impact of synthetic biology on current (re-)theorizing of vitalism. (shrink)

Canguilhem is known to have regretted, with some pathos, that Life no longer serves as an orienting question in our scientific activity. He also frequently insisted on a kind of uniqueness of organisms and/or living bodies – their inherent normativity, their value-production and overall their inherent difference from mere machines. In addition, Canguilhem acknowledged a major debt to the German neurologist-theoretician Kurt Goldstein, author most famously of The Structure of the Organism in 1934; along with Merleau-Ponty, Canguilhem was the main (...) figure who introduced the work of Goldstein and his ‘phenomenology of embodiment’ into France. In this paper I inquire if we should view Canguilhem and Goldstein as ‘biochauvinists’, that is, as thinkers who consider that there is something inherently unique about biological entities as such, and if so, of what sort. (shrink)

It is commonly thought that before the introduction of quantum mechanics, determinism was a straightforward consequence of the laws of mechanics. However, around the nineteenth century, many physicists, for various reasons, did not regard determinism as a provable feature of physics. This is not to say that physicists in this period were not committed to determinism; there were some physicists who argued for fundamental indeterminism, but most were committed to determinism in some sense. However, for them, determinism was often not (...) a provable feature of physical theory, but rather an a priori principle or a methodological presupposition. Determinism was strongly connected with principles of causality and continuity and the principle of sufficient reason; this thesis examines the relevance of these principles in the history of physics. Moreover, the history of determinism in this period shows that there were essential changes in the relation between mathematics and physics: whereas in the eighteenth century, there were metaphysical arguments which lent support to differential calculus, by the early twentieth century the development of rigorous foundations of differential calculus led to concerns about its applicability in physics. The thesis consists of six papers. In the first paper, "On the origins and foundations of Laplacian determinism", I argue that Laplace, who is usually pointed out as the first major proponent of scientific determinism, did not derive his statement of determinism directly from the laws of mechanics; rather, his determinism has a background in eighteenth century Leibnizian metaphysics, and is ultimately based on the law of continuity and the principle of sufficient reason. These principles also provided a basis for the idea that one can find laws of nature in the form of differential equations which uniquely determine natural processes. In "The Norton dome and the nineteenth century foundations of determinism", I argue that an example of indeterminism in classical physics which has attracted attention in philosophy of physics in recent years, namely the Norton come, was already discussed during the nineteenth century. However, the significance which this type of indeterminism had back then is very different from the significance which the Norton dome currently has in philosophy of physics. This is explained by the fact that determinism was conceived of in an essentially different way: in particular, the nineteenth century authors who wrote about this type of indeterminism regarded determinism as an a priori principle rather than as a property of the equations of physics. In "Vital instability: life and free will in physics and physiology, 1860-1880", I show how Maxwell, Cournot, Stewart and Boussinesq used the possibility of unstable or indeterministic mechanical systems to argue that the will or a vital principle can intervene in organic processes without violating the laws of physics, so that a strictly dualist account of life and the mind is possible. Moreover, I show that their ideas can be understood as a reaction to the law of conservation of energy and to the way it was used in physiology to exclude vital and mental causes. In "The nineteenth century conflict between mechanism and irreversibility", I show that in the late nineteenth century, there was a widespread conflict between the aim of reducing physical processes to mechanics and the recognition that certain processes are irreversible. Whereas the so-called reversibility objection is known as an objection that was made to the kinetic theory of gases, it in fact appeared in a wide range of arguments, and was susceptible to very different interpretations. It was only when the project of reducing all of physics to mechanics lost favor, in the late nineteenth century, that the reversibility objection came to be used as an argument against mechanism and against the kinetic theory of gases. In "Continuity in nature and in mathematics: Boltzmann and Poincaré", I show that the development of rigorous foundations of differential calculus in the nineteenth century led to concerns about its applicability in physics: through this development, differential calculus was made independent of empirical and intuitive notions of continuity and was instead based on mathematical continuity conditions, and for Boltzmann and Poincaré, the applicability of differential calculus in physics depended on whether these continuity conditions could be given a foundation in intuition or experience. In the final paper, "Determinism around 1900", I briefly discuss the implications of the developments described in the previous two papers for the history of determinism in physics, through a discussion of determinism in Mach, Poincaré and Boltzmann. I show that neither of them regards determinism as a property of the laws of mechanics; rather, for them, determinism is a precondition for science, which can be verified to the extent that science is successful. (shrink)