Oversight of human gene transfer research presents an important model with potential application to oversight of nanobiology research on human participants. Gene therapy oversight adds centralized federal review at the National Institutes of Health's Office of Biotechnology Activities and its Recombinant DNA Advisory Committee to standard oversight of human subjects research at the researcher's institution and at the federal level by the Office for Human Research Protections. The Food and Drug Administration's Center for Biologics Evaluation and Research oversees human gene (...) transfer research in parallel, including approval of protocols and regulation of products. This article traces the evolution of this dual oversight system; describes how the system is already addressing nanobiotechnology in gene transfer: evaluates gene therapy oversight based on public opinion, the literature, and preliminary expert elicitation; and offers lessons of the gene therapy oversight experience for oversight of nanobiotechnology. (shrink)

This article explores the role of the five “abodes” (or “intellectual powers” or “mental properties”) of the Light Realm in the narrative of Mani’s Living Gospel according to the Coptic Synaxeis codex. Far from being spared in the war effort (as it appears from Theodore bar Koni’s report on Mani’s doctrine), these five powers can be seen in Mani’s narrative to be active contributors not only to the generation of each divine persona newly called into being but also in the (...) actual fight against the forces of Darkness, securing their final defeat. (shrink)

Several publications with healthcare professionals, such as psychotherapists, have shown a significant difference in personality styles in practitioners using hypnosis compared to those not using hypnosis. To investigate differences in personality styles, dentists were contacted to participate in a personality-inventory [Personality Style and Disorder Inventory ] online survey. Dentists using hypnosis were compared to dentists not using hypnosis. Results show that hypnosis-practicing dentists score significantly higher in the intuitive/schizotypal ST personality style compared to non-hypnosis-practicing dentists. Female dentists scored significantly higher (...) in intuitive/schizotypal ST and unselfish/self-sacrificing SL in the HYP DGZH sample but only in unselfish/self-sacrificing SL in the NONHYP DENT sample. The percentage of women was similar in both samples. Intuitive/schizotypal ST was found to be the predominant personality style of men who are interested in or use hypnosis, metaphorically so-called “homo hypnoticus.” Within the limitations of this cross-sectional non-interventional observational online-questionnaire study, results expand this notion to the so-called “homo hypnoticus dentalis.” However, further research on the subject is needed to investigate and confirm this personality type in other than the German-speaking DACH countries. (shrink)

Theories of embodied cognition hypothesize interdependencies between psychological well-being and physical posture. The purpose of this study was to assess the feasibility of objectively measuring posture, and to explore the relationship between posture and affect and other patient centered outcomes in breast cancer survivors with persistent postsurgical pain over a 12-week course of therapeutic Qigong mind-body training. Twenty-one BCS with PPSP attended group Qigong training. Clinical outcomes were pain, fatigue, self-esteem, anxiety, depression, stress and exercise self-efficacy. Posture outcomes were vertical (...) spine and vertical head angles in the sagittal plane, measured with a 3D motion capture system in three conditions: eyes open, eyes open relaxed and eyes closed. Assessments were made before and after the Qigong training. The association between categorical variables was measured by Cramer’s V. In the EO condition, most participants who improved in fatigue and anxiety scales also had better vertical head values. For the EOR condition, a moderate correlation was observed between changes in vertical head angle and changes in fatigue scale. In the EC condition, most of the participants who improved in measures of fatigue also improved vertical head angle. Additionally, pain severity decreased while vertical spine angle improved. These preliminary findings support that emotion and other patient centered outcomes should be considered within an embodied framework, and that Qigong may be a promising intervention for addressing biopsychosocially complex interventions such as PPSP in BCSs. (shrink)

Cognitive functions like perception, memory, language, or consciousness are based on highly parallel and distributed information processing by the brain. One of the major unresolved questions is how information can be integrated and how coherent representational states can be established in the distributed neuronal systems subserving these functions. It has been suggested that this so-called ''binding problem'' may be solved in the temporal domain. The hypothesis is that synchronization of neuronal discharges can serve for the integration of distributed neurons into (...) cell assemblies and that this process may underlie the selection of perceptually and behaviorally relevant information. As we intend to show here, this temporal binding hypothesis has implications for the search of the neural correlate of consciousness. We review experimental results, mainly obtained in the visual system, which support the notion of temporal binding. In particular, we discuss recent experiments on the neural mechanisms of binocular rivalry which suggest that appropriate synchronization among cortical neurons may be one of the necessary conditions for the buildup of perceptual states and awareness of sensory stimuli. (shrink)

In dem Sammelband, der als Festschrift zum 65. Geburtstag von Franz Hundsnurscher erscheint, sind 47 Beiträge zu zwei thematischen Schwerpunkten versammelt, die im Werk Hundsnurschers von zentraler Bedeutung sind: Semantik und Dialoganalyse. Im ersten Teil werden neben grundlegenden Fragen der Semantik Aspekte der semantischen Beschreibung von Phraseologismen, des Fremdwortgebrauchs und des Grundwortschatzes diskutiert; neben synchronen (meist gebrauchstheoretischen) Untersuchungen zu Einzelwörtern und Quasisynonymengruppen im Deutschen stehen sprachhistorische und kontrastive Arbeiten. Vor allem mit theoretischen und methodologischen Fragen der Dialoganalyse, mit Fragen der (...) Analyse institutioneller Kommunikation (Politik, Recht, Wirtschaft) und literarischer Dialoge setzen sich die Beiträge des zweiten Teils auseinander. (shrink)

El artículo se propone determinar los asuntos que competen a la filosofía y a la literatura a partir de, primero, un contexto común, el de la totalidad; y segundo, dos perspectivas, a saber, la cuestión por la relación de la filosofía y la literatura con la totalidad, y la relevancia ética y moral de dicha relación. La totalidad debe ser entendida de tres formas: la de la realidad y del mundo; la de las relaciones de los hombres con el mundo (...) y su comprensión; y, la de la vida individual. Estas variaciones del concepto son elaboradas por Peter Handke y presentadas como apoyo discursivo por Ursula Wolf. (shrink)

Peer review is a widely accepted instrument for raising the quality of science. Peer review limits the enormous unstructured influx of information and the sheer amount of dubious data, which in its absence would plunge science into chaos. In particular, peer review offers the benefit of eliminating papers that suffer from poor craftsmanship or methodological shortcomings, especially in the experimental sciences. However, we believe that peer review is not always appropriate for the evaluation of controversial hypothetical science. We argue that (...) the process of peer review can be prone to bias towards ideas that affirm the prior convictions of reviewers and against innovation and radical new ideas. Innovative hypotheses are thus highly vulnerable to being “filtered out” or made to accord with conventional wisdom by the peer review process. Consequently, having introduced peer review, the Elsevier journal Medical Hypotheses may be unable to continue its tradition as a radical journal allowing discussion of improbable or unconventional ideas. Hence we conclude by asking the publisher to consider re-introducing the system of editorial review to Medical Hypotheses. (shrink)

Summary A large survey of German and Israeli younger and older adolescents was conducted to reveal their opinions and attitudes towards violence and aggression, their personal engagement in aggressive and violent behaviors in and outside the school environment, their attitudes toward physical activity, their engagement in physical activity, and the linkage between physical activity engagement and conductance of violence and aggression. The findings point out that there are more similarities than differences between German and Israeli adolescents concerning violence and aggression (...) in and outside schools. No linkage between physical activity involvement and the extent of violent and/or aggressive acts is found. The findings pertaining adolescents’ opinions and attitudes toward aggression and violence and their behaviors in and outside school are encouraging. (shrink)

Balancing Change and Tradition in Global Education Reform is an invaluable resource for policymakers, faculty, students, and anyone interested in how decisions made about the education system ultimately affect the quality of education, educational access, and social justice.

"Charles Marville is widely acknowledged as one of the most talented photographers of the nineteenth century. Accompanying a major retrospective exhibition at the National Gallery of Art in honor of Marville's bicentennial, Charles Marville: Photographer of Paris surveys the artist's entire career. This beautiful book, which begins with the city scenes and architectural views Marville made throughout France and Germany in the 1850s, also explores his portraits and landscapes s before turning to his photographs of Paris made both before and (...) after the city's dramatic modernization in the 1850s and 1860s. Commissioned to record the city in transition, Marville created one of the earliest and most powerful photographic series documenting urban transformation on a grand scale. Despite the importance of his work, Marville has long been an enigma in the history of photography, in part because many of the documents about his life were thought to have been lost in a fire that destroyed Paris's city hall in 1871. Based on meticulous research, this volume reveals many new insights into Marville's personal and professional biography, including the central fact that he was born Charles-Franðcois Bossu. He shed this name and adoptedthe pseudonym Marville when he began his career as an illustrator in the 1830s. With five essays by respected scholars, this book offers the first comprehensive examination of Marville's life and career and delivers the much-awaited public recognition his photographs so richly deserve"--. (shrink)

- L'articolo risponde negativamente alla domanda, a partire dall'assunto che le persone non devono essere sacrificate nel nome di privilegi, ideali o altre persone. L'egoismo etico, quale č celebrato nell'Unico e la sua proprietÀ di Max Stirner, pare essere un efficace antidoto contro le eccessive pretese morali altrui. Infatti, l'origine del problema della sostituibilitÀ non risiede, come pensa Peter Singer, nell'edonismo, bensě nella imparzialitÀ forte dell'etica kantiana e di quella utilitarista, che escludono qualunque ragione egoistica dalla scelta morale.

This article traces my own pedagogical journey to find strategies for teaching critical thinking that emphasize intellectual cooperation, empathy, and argument repair, a journey that found me frequently turning to sources outside of philosophy, including work in intergroup dialogue and pedagogical work in rhetoric and composition. Theoretically, the article showcases Maureen Linker’s notion of ‘cooperative reasoning’, sets it against the ‘adversary paradigm’ Janice Moulton critiques, and illustrates how Peter Elbow’s challenges to critical thinking as a ‘doubting game’ resonate with (...) Linker’s work. Practically, it illustrates the structure and the role of peer-to-peer dialogues in my own reasoning classroom, an enactment of a cooperative, belief-based approach to reasoning inspired by Linker and Elbow alike, while also learning from the methodologies of intergroup dialogue. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Ethics & the Environment 8.2 (2003) 106-125 [Access article in PDF] Leopold's NovelThe Land Ethic in Barbara Kingsolver's Prodigal Summer Peter S. Wenz Introduction Like many good novels, Prodigal Summer's 1 account of love, tragedy, conflict, and choice in human relationships conveys an overall message about how life should be lived. In this case the message corresponds to Aldo Leopold's call for "a land ethic [that] changes the (...) role of Homo sapiens from conqueror of the land-community to plain member and citizen of it." People should "respect... fellow-members and also... the community as such." 2 Barbara Kingsolver explains Leopold's key ideas and updates the Land Ethic by showing how it might guide people today. The present paper selectively displays this relationship, and then suggests some pedagogical advantages of fiction.Prodigal Summer tells three interconnected stories that take place from May through July one year in contemporary rural Kentucky. One story features Deanna Wolfe, who has spent the last 25 months working for the U.S. Forest Service in a wilderness area on Zebulon Mountain where she restores trails and impedes illegal hunting. She has just discovered that coyotes have arrived, but so has Eddie Bondo, a handsome man from the West who hates coyotes because they sometimes kill livestock. [End Page 106]Another story features Lusa Landowski and her husband Cole Widener. Lusa is an entomologist who taught at the University of Kentucky before marrying Cole and moving to his family's tobacco farm that adjoins the national forest where Deanna works. Cole dies early in the novel and Lusa tries to save the family farm.Finally, Nannie Rawley is a senior citizen who grows organic apples nearby and has conflicts with her more senior neighbor, Garnett Walker, who wants to kill weeds with chemicals to keep his property looking neat. Garnett's goal is to cross-fertilize chestnut trees to create an American chestnut that is immune to chestnut blight. Ecocentrism, Hunting, the Biotic Pyramid, and Exotic Species Aldo Leopold's Land Ethic is famously holistic and ecocentric. The ecosystem, a holistic entity, has value over and above, and in most cases more than, the value of its individual components. This ecocentric perspective is summed up in the maxim: "A thing is right when it tends to preserve the integrity, stability, and beauty of the biotic community. It is wrong when it tends otherwise" (1970, 262).Ecocentrism explains Leopold's attitude toward hunting. In many passages, such as the October account of hunting ruffed grouse (58-62) and partridge (62-69), Leopold describes the hunt with approval. However, he disapproves of programs to eradicate keystone predators because their elimination impoverishes ecosystems. His classic account, "Thinking Like a Mountain," concerns wolf eradication. He writes, "I thought that because fewer wolves meant more deer, that no wolves would mean hunters' paradise" (138). But he found that wolf eradication harms mountains, that is, ecosystems. I have watched the face of many a newly wolfless mountain, and seen the south-facing slopes wrinkle with a maze of new deer trails. I have seen every edible bush and seedling browsed, first to anaemic desuetude, and then to death. I have seen every edible tree defoliated to the height of a saddle horn.... In the end the starved bones of the hoped-for deer herd, dead of its own too-much, bleach with the bones of the dead sage, or molder under the high-lined junipers. (139-40) Leopold's concept of a biotic pyramid explains why wolf eradication harms ecosystems. According to Leopold, the energy that plants absorb from the sun: [End Page 107]... flows through a circuit called the biota, which may be represented by a pyramid consisting of layers. The bottom layer is the soil. A plant layer rests on the soil, an insect layer on the plants, a bird and rodent layer on the insects, and so on up through the various animal groups to the apex layer, which consists of the larger carnivores.... Proceeding upward, each successive layer decreases in numerical... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Ethics & the Environment 8.2 (2003) 106-125 [Access article in PDF] Leopold's NovelThe Land Ethic in Barbara Kingsolver's Prodigal Summer Peter S. Wenz Introduction Like many good novels, Prodigal Summer's 1 account of love, tragedy, conflict, and choice in human relationships conveys an overall message about how life should be lived. In this case the message corresponds to Aldo Leopold's call for "a land ethic [that] changes the (...) role of Homo sapiens from conqueror of the land-community to plain member and citizen of it." People should "respect... fellow-members and also... the community as such." 2 Barbara Kingsolver explains Leopold's key ideas and updates the Land Ethic by showing how it might guide people today. The present paper selectively displays this relationship, and then suggests some pedagogical advantages of fiction.Prodigal Summer tells three interconnected stories that take place from May through July one year in contemporary rural Kentucky. One story features Deanna Wolfe, who has spent the last 25 months working for the U.S. Forest Service in a wilderness area on Zebulon Mountain where she restores trails and impedes illegal hunting. She has just discovered that coyotes have arrived, but so has Eddie Bondo, a handsome man from the West who hates coyotes because they sometimes kill livestock. [End Page 106]Another story features Lusa Landowski and her husband Cole Widener. Lusa is an entomologist who taught at the University of Kentucky before marrying Cole and moving to his family's tobacco farm that adjoins the national forest where Deanna works. Cole dies early in the novel and Lusa tries to save the family farm.Finally, Nannie Rawley is a senior citizen who grows organic apples nearby and has conflicts with her more senior neighbor, Garnett Walker, who wants to kill weeds with chemicals to keep his property looking neat. Garnett's goal is to cross-fertilize chestnut trees to create an American chestnut that is immune to chestnut blight. Ecocentrism, Hunting, the Biotic Pyramid, and Exotic Species Aldo Leopold's Land Ethic is famously holistic and ecocentric. The ecosystem, a holistic entity, has value over and above, and in most cases more than, the value of its individual components. This ecocentric perspective is summed up in the maxim: "A thing is right when it tends to preserve the integrity, stability, and beauty of the biotic community. It is wrong when it tends otherwise" (1970, 262).Ecocentrism explains Leopold's attitude toward hunting. In many passages, such as the October account of hunting ruffed grouse (58-62) and partridge (62-69), Leopold describes the hunt with approval. However, he disapproves of programs to eradicate keystone predators because their elimination impoverishes ecosystems. His classic account, "Thinking Like a Mountain," concerns wolf eradication. He writes, "I thought that because fewer wolves meant more deer, that no wolves would mean hunters' paradise" (138). But he found that wolf eradication harms mountains, that is, ecosystems. I have watched the face of many a newly wolfless mountain, and seen the south-facing slopes wrinkle with a maze of new deer trails. I have seen every edible bush and seedling browsed, first to anaemic desuetude, and then to death. I have seen every edible tree defoliated to the height of a saddle horn.... In the end the starved bones of the hoped-for deer herd, dead of its own too-much, bleach with the bones of the dead sage, or molder under the high-lined junipers. (139-40) Leopold's concept of a biotic pyramid explains why wolf eradication harms ecosystems. According to Leopold, the energy that plants absorb from the sun: [End Page 107]... flows through a circuit called the biota, which may be represented by a pyramid consisting of layers. The bottom layer is the soil. A plant layer rests on the soil, an insect layer on the plants, a bird and rodent layer on the insects, and so on up through the various animal groups to the apex layer, which consists of the larger carnivores.... Proceeding upward, each successive layer decreases in numerical... (shrink)

The Prince and the Wolf contains the transcript of a debate which took place on February 5, 2008 at the London School of Economics (LSE) between the prominent French sociologist, anthropologist, and philosopher Bruno Latour and the Cairo-based American philosopher Graham Harman.

Ansel Adams, Robert Adams, Carlos Almaraz, Robert Arneson, John Baldessari, Lewis Baltz, Robert Bechtle, Jeff Brouws, Laurie Brown, Angela Buenning, Darlene Campbell, Mark Campbell, Gary Carlos, Fandra Chang, Stephane Couturier, Robert Dawson, Joe Deal, Richard Diebenkorn, John Divola, Beth Yarnelle Edwards, Kota Ezawa, William A. Garnett, Jeff Gillette, Joe Goode, Todd Hido, David Hockney, Salomon Huerta, Robert Isaacs, Thomas Lawson, Jean Lowe, Alex MacLean, Richard Meisinger, Jr., Richard Misrach, Rick Monzon, Barrie Mottishaw, Martin Mull, Deborah Oropallo, Bill Owens, Rondal Partridge, (...) John Register, Ed Ruscha, Peter Saul, Mary Snowden, Joel Sternfeld, Larry Sultan, Rudy Vanderlans, Camilo Jose Vergara, Henry Wessel, Amir Zaki. (shrink)

With the publication of The God Delusion Richard Dawkins became enthroned as the unofficial ‘Emperor’ for a cadre of writers advancing a rhetorically robust form of anti-theism dubbed ‘The New Atheism’ by Wired Magazine contributing editor Gary Wolf. Many have cheered Dawkins and his court, seeing in their writings just what they long to see. For, after the fashion of the fairy-tale Emperor's fabled new clothes, the ‘new atheism’ has seen naturalism wrapping itself in a fake finery of counterfeit meaning (...) and purpose. (shrink)