Peer review is a widely accepted instrument for raising the quality of science. Peer review limits the enormous unstructured influx of information and the sheer amount of dubious data, which in its absence would plunge science into chaos. In particular, peer review offers the benefit of eliminating papers that suffer from poor craftsmanship or methodological shortcomings, especially in the experimental sciences. However, we believe that peer review is not always appropriate for the evaluation of controversial hypothetical science. We argue that (...) the process of peer review can be prone to bias towards ideas that affirm the prior convictions of reviewers and against innovation and radical new ideas. Innovative hypotheses are thus highly vulnerable to being “filtered out” or made to accord with conventional wisdom by the peer review process. Consequently, having introduced peer review, the Elsevier journal Medical Hypotheses may be unable to continue its tradition as a radical journal allowing discussion of improbable or unconventional ideas. Hence we conclude by asking the publisher to consider re-introducing the system of editorial review to Medical Hypotheses. (shrink)

Les travaux du Comité public de suivi Le comité a été créé le 12 avril 2016. À cette occasion, il a annoncé le dépôt d’un rapport de suivi à l’occasion du premier anniversaire du dépôt du rapport de la Commission Charbonneau. Dans les derniers mois, le comité s’est penché sur les initiatives répondant aux recommandations de la Commission, en étudiant les informations rendues publiques sur ce sujet. Aidé d’une équipe...

This paper reviews Deleuze’s theory of language in Logic of Sense, and Deleuze and Guattari’s theory of language in A Thousand Plateaus. In the ontology informed by the Stoics described in those books, human being and language do not exist separately but in a mixture of words and things. The author argues that this flattened ontology of surfaces is incommensurable with the ontology of depth used in conventional humanist qualitative methodology and recommends beginning new empirical inquiry with a concept instead (...) of with method and methodology. (shrink)

Musing for Puncta special issue "Critically Sick: New Phenomenologies Of Illness, Madness, And Disability.".

En décrivant la vieillesse comme l’une des modalités d’équilibre possibles des qualités premières qui assurent une santé à l’individu, les auteurs du Corpus hippocratique évitent d’associer systématiquement le vieillissement et la dégénérescence. Cet aspect singulier du corpus comporte pour nous un intérêt éthique : il prémunit contre l’âgisme médical. Cet article aborde la question des différences physiologiques qui caractérisent chacun des âges de la vie en insistant sur le fait que cette conception favorise un traitement égalitaire des patients relativement à (...) l’âge. (shrink)

Le dernier ouvrage d’Antony McKenna, intitulé Pascal et son libertin, présente en une synthèse claire et précise les résultats de plus de trente années consacrées par l’auteur aux études pascaliennes et à l’étude de la pensée libertine de la période classique. Auteur d’une thèse d’État publiée sous le titre De Pascal à Voltaire : le rôle des Pensées de Pascal dans l’histoire des idées entre 1670 et 1734 puis de plus d’une centaine d’études d’histoire de la philosophie du XVIIe et (...) du XVIIIe si... (shrink)

This study investigated the modus operandi strategies employed by 120 coaches who committed sexual abuse toward 331 athletes under their authority. More than 2,000 Canadian court judgements and media reports were identified using online search databases. Using descriptive analysis, 51 strategies used in six modus operandi stages were identified. Results highlighted the most frequent strategies used by coaches for each stage of the crime commission process. Additionally, findings revealed the influence of the victims' gender, coaches' sport level and year of (...) coaches' first offenses on modus operandi strategies used. Implications for crime prevention measures are discussed. (shrink)

This essay argues that Speech-Language Pathology emerged as a response to the early twentieth-century demand for docile, efficient, and thus productive speech. As the capacity of speech became more central to the industrial and democratic operations of modern society, an apparatus was needed to bring speech under the fold of biopower. Beyond simple economic productivity, the importance of SLP lies in opening the speaking subject up to management and normalization—creating, in short, biopolitical subjects of communication. We argue that SLP accordingly (...) emerged not as a discreet institution, but as a set of practices which can be clustered under three headings: calculating deviance, disciplining the tongue, and speaking the truth of pathologized subjects. (shrink)

I don’t agree that postmodernism and poststructuralism are dead, any more than are Platonism, Cartesianism, phenomenology, pragmatism, Frankfurt School critical theory, feminist theory, critical ra...

« La vie s’est transformée en une suite intemporelle de chocs », écrivait Adorno, dans ses Minima Moralia, pour décrire l’expérience du front lors de la Seconde Guerre mondiale. À partir de la notion de choc, qui ponctue l’ensemble de l’oeuvre d’Adorno, se dégage en fait une problématique plus générale d’une crise de l’expérience moderne. En mettant en évidence certains parallèles entre les thèmes de la philosophie d’Adorno et la théorie psychanalytique du choc traumatique, j’entends cerner avec plus de précision (...) la teneur de la crise dont il est question, ses conséquences, ainsi que les possibilités qu’entrevoit le philosophe pour y mettre un terme.Reflecting upon the experience of the battle line during the Second World War, Adorno claimed that “life has changed into a timeless succession of shocks”. From this concept of shock, which punctuates the whole of Adorno’s work, emerges the more general problem of the crisis of modern experience. By drawing parallels between aspects of Adorno’s philosophy and of the psychoanalytic theory of traumatic shock, I intend to define more precisely the content of this crisis, its consequences, and the possibilities for its resolution glimpsed by the philosopher. (shrink)

In the intersection between eugenics past and present, disability has never been far beneath the surface. Perceived and ascribed disabilities of body and mind were one of the core sets of eugenics traits that provided the basis for institutionalized and sterilization on eugenic grounds for the first 75 years of the 20th-century. Since that time, the eugenic preoccupation with the character of future generations has seeped into what have become everyday practices in the realm of reproductive choice. As Marsha Saxton (...) (2000) and Adrienne Asch (2000, 2003) have forcefully argued, the use of prenatal screening technologies to facilitate the selective abortion of fetuses with features that signify disabling traits—the paradigm here being trisomy 21 in a fetus indicating Down Syndrome in the child—express a negative view of such disabilities sufficient to warrant terminating an otherwise wanted pregnancy. The eliminative structure of what Rosemary Garland Thompson (2012) has called eugenic logic persists in contemporary practices governing reproductive choice, social inclusion, and democratic participation and their relationship to disability. The tie between eugenics and contemporary disability studies suggests that eugenics and reflection on its history can also play a more positive role in disability politics. After focusing on eugenics in the first half of the paper, we will shift in the second half of the paper to eugenic resonances in contemporary thought and practice, concluding with some thoughts about ongoing practices of silencing and the very idea of eradicating disability. (shrink)

This article addresses the issue of the interface between public health and clinical health within the context of the search for networking approaches geared to a more integrated delivery of health services. The articulation of an operative interface is complicated by the fact that the definition of networking modalities involves complex intra- and interdisciplinary and intra- and interorganizational systems across which a new transversal dynamics of intervention practices and exchanges between service structures must be established. A better understanding of the (...) situation is reached by shedding light on the rationale underlying the organizational methods that form the bases of the interface between these two sectors of activity. The Quebec experience demonstrates that neither the structural-functionalist approach, which emphasizes remodelling establishment structures and functions as determinants of integration, nor the structural-constructivist approach, which prioritizes distinct fields of practice in public health and clinical health, adequately serves the purpose of networking and integration. Consequently, a theoretical reframing is imperative. In this regard, structuration theory, which fosters the simultaneous study of methods of inter-structure coordination and inter-actor cooperation, paves the way for a better understanding of the situation and, in turn, to the emergence of new integration possibilities. (shrink)

Denunciations of child sexual abuse in the sport context have been increasing in the last decades. Studies estimate that between 14 and 29% of athletes have been victim of at least one form of sexual violence in sport before the age of 18. However, studies suggest that many do not disclose their experience of CSA during childhood. This finding is alarming since studies have shown that the healing process usually starts with disclosure. Moreover, little is known about the healing process (...) of CSA experienced in the sport context. The aim of the study is to present a single case study of a CSA in sport to better understand the global experience over time from the perspective of the athlete. A narrative inquiry approach was adopted. Three non-structured interviews were conducted with the participant. Three pathways in the survivor journey have been identified through inductive thematic analysis: pathway to understanding, pathway to disclosure, and pathway to healing. These pathways represent distinct processes but are intertwined as they are dynamic and iterative. Indeed, the survivor explained how she had been, and is still, going back and forth between them. Results are consistent with those found in the literature on CSA in the general population. It suggests that theoretical models of CSA in the general population could be applied to CSA in sport. Practical implications include a need for education and clearer boundaries in the coach-athlete relationship. Sport stakeholders also need to be better equipped to recognize the signs of sexual violence in sport. Our results indicate that qualitative research could be a potential avenue to help victims heal from CSA. It gives them the chance to talk about and make sense of their abuse in a safe space. Finally, our results demonstrate the importance of reviewing the current justice system for victims. It should be based on a trauma-informed approach that places the victim at the center of the judicial process. (shrink)

What is the future of Philosophy of education? Or as many of scholars and thinkers in this final ‘future-focused’ collective piece from the philosophy of education in a new key Series put it, what are the futures—plural and multiple—of the intersections of ‘philosophy’ and ‘education?’ What is ‘Philosophy’; and what is ‘Education’, and what role may ‘enquiry’ play? Is the future of education and philosophy embracing—or at least taking seriously—and thinking with Indigenous ethicoontoepistemologies? And, perhaps most importantly, what is that (...) ‘Future’? These debates have been located in the work of diverse scholars: from the West, from Global South, from indigenous thinkers. In this collective piece, we purposefully juxtapose diverse takes on the future of these intersections. We have given up the urge to organise, place together, separate with subheadings or connect the paragraphs that follow. Instead, we let these philosophers of education and thinkers who use philosophical texts and ideas to sit together in one long read as potentially ‘strange and unusual bedfellows’. This text urges us to understand how these scholars and thinkers perceive our educational philosophical futures, and how the work and thinking they have done on thinking about what the future of that new key in philosophy of education may look like is embedded in a much deeper and richer literature, and personal experience. (shrink)

Personality and prayer are both conceptualized as focusing on issues of connectivity with the self and beyond. Individual participants each recruited a peer to join the study . Participants rated themselves according to multi-item scales that detail five personality factors . They also responded to an instrument specifying eight foci of the inward, outward, and upward cognitive content of prayer ; these eight foci were reduced to three prayer themes: internal concerns, embracing paradox, and bold assertion. Finally, respondents reported the (...) strength of six "basic" emotions that may be experienced during their typical prayer. Using the same instruments, each peer rated her or his matched participant. Results reveal discrete patterns between self and peer ratings, with respect to links among prayer and personality variables. Both self and peer ratings emphasize a relation between prayer and the personality traits of agreeableness and conscientiousness . Several concluding points highlight the value of the present conceptualization of personality and prayer with relation to connectivity, potential differences between personal and corporate prayers, and the potential role of sex differences in the disclosure of prayer's content and emotional influence. (shrink)

Glycerol is a small and simple molecule produced in the breakdown of glucose, proteins, pyruvate, triacylglycerols and other glycerolipid, as well as release from dietary fats. An increasing number of observations show that glycerol is probably involved in a surprising variety of physiopathologic mechanisms. Glycerol has long been known to play fundamental roles in several vital physiological processes, in prokaryotes and eukaryotes, and is an important intermediate of energy metabolism. Despite some differences in the details of their operation, many of (...) these mechanisms have been preserved throughout evolution, demonstrating their fundamental importance. In particular, glycerol can control osmotic activity and crystal formation and then act as a cryoprotective agent. Furthermore, its properties make it useful in numerous industrial, therapeutic and diagnostic applications. Few studies have focussed directly on glycerol, however, and while its metabolism is increasingly well documented, much of the details remain unknown. Considering the importance of glycerol in multiple vital physiological processes, its study could help unlock important physiopathological mechanisms. BioEssays 23:534–542, 2001. © 2001 John Wiley & Sons, Inc. (shrink)

A lone fish swims haphazardly in any direction, but. if we get enough fish of the same species together so that neighboring individual fish may exchange signals, they adopt a common direction. Here we have a phenomenon of cooperation: many individuals find themselves in strong interaction with each other, and overall behavior is noticeably affected.

Drawing upon feminist, queer, and crip phenomenology, this essay argues that the distinct temporality of the lived, stuttering body disturbs the normalized “choreography” of communication and thereby threatens the disabled speaker's recognition as a speaking subject. Examined through the phenomenology of Maurice Merleau-Ponty and Alfred Schutz, the disabled speaking body is temporally “out of step” with the normalized bodily rhythms and pace of communicative practices in relation to both lived and objective time. Disciplined for his incalculable and therefore irrational bodily (...) choreography, the disabled speaker is foregrounded against an objective, instrumentally ordered world constituted by a disembodied and hegemonic “straight-masculine” time. Although dominant communicative choreographies may often be unlivable for disabled speakers, cripping communicative time rejects the cardinal value of futurity and invites interlocutors to gather in a noninstrumentalized and nonproductive present. This reshaping of communicative space enacts new modes of relationality and opens up an array of communicative futures suppressed or cut off by straight-masculine time. (shrink)

Women and Comedy: History, Theory, Practice brings together leading researchers from Canada, the United States, and Europe in an interdisciplinary collection of essays to chart the future of critical inquiry in gender and comedy studies.

This paper is concerned with adaptive learning and coordination processes. Implementing agent-based modeling techniques (Learning Classifier Systems, LCS), we focus on the twofold impact of cognitive and environmental complexity on learning and coordination. Within this framework, we introduce the notion of Adaptive Learning Agent with Rule-based Memory (ALARM), which is a particular class of Artificial Adaptive Agent (AAA, Holland and Miller 1991). We show that equilibrium is approached to a high degree, but never perfectly reached. We also demonstrate that memorization (...) and learning capacities depend upon the relative discordance between the cognitive complexity of agents' mental models and the degree of stability of the environment. (shrink)

Widespread preservation of fossilized biomolecules in many fossil animals has recently been reported in six studies, based on Raman microspectroscopy. Here, we show that the putative Raman signatures of organic compounds in these fossils are actually instrumental artefacts resulting from intense background luminescence. Raman spectroscopy is based on the detection of photons scattered inelastically by matter upon its interaction with a laser beam. For many natural materials, this interaction also generates a luminescence signal that is often orders of magnitude more (...) intense than the light produced by Raman scattering. Such luminescence, coupled with the transmission properties of the spectrometer, induced quasi‐periodic ripples in the measured spectra that have been incorrectly interpreted as Raman signatures of organic molecules. Although several analytical strategies have been developed to overcome this common issue, Raman microspectroscopy as used in the studies questioned here cannot be used to identify fossil biomolecules. (shrink)

To help infer the meanings of novel words, children frequently capitalize on their current linguistic knowledge to constrain the hypothesis space. Children's syntactic knowledge of function words has been shown to be especially useful in helping to infer the meanings of novel words, with most previous research focusing on how children use preceding determiners and pronouns/auxiliary to infer whether a novel word refers to an entity or an action, respectively. In the current visual world experiment, we examined whether 28‐ to (...) 32‐month‐olds could exploit their lexical semantic knowledge of an additional class of function words—prepositions—to learn novel nouns. During the experiment, children were tested on their ability to use the prepositions in, on, under, and next to to identify novel creatures displayed on a screen (e.g., The wug is on the table), as well as their ability to later identify the creature without accompanying prepositions (e.g., Look at the wug). Children overall demonstrated understanding of all the prepositions but next to and were able to use their knowledge of prepositions to learn the associations between novel words and their intended referents, as shown by greater‐than chance looks to the target referent when no prepositional phrase was provided. (shrink)

Adults are skilled at using language to construct/negotiate identity and to signal affiliation with others, but little is known about how these abilities develop in children. Clearly, children mirror statistical patterns in their local environment (e.g., Canadian children using zed instead of zee), but do they flexibly adapt their linguistic choices on the fly in response to the choices of different peers? To address this question, we examined the effect of group membership on 7‐ to 9‐year‐olds' labeling of objects in (...) a trivia game, exploring whether they were more likely to use a particular label (e.g., sofa vs. couch) if members of their “team” also used that label. In a preregistered study, children (N = 72) were assigned to a team (red or green) and were asked during experimental trials to answer questions—which had multiple possible answers (e.g., blackboard or chalkboard)—after hearing two teammates and two opponents respond to the same question. Results showed that children were significantly more likely to produce labels less commonly used by the community (i.e., dispreferred labels) when their teammates had produced those labels. Crucially, this effect was tied to group membership, and could not be explained by children simply repeating the most recently used label. These findings demonstrate how social processes (i.e., group membership) can guide linguistic variation in children. (shrink)

Three studies were conducted to assess prevalent stereotypes regarding men's and women's emotional expressivity as well as self-perceptions of their emotional behaviour. Emotion profiles were employed to assess both modal emotional reactions and secondary emotional reactions to hypothetical events and personal experiences. In Study 1 we asked how men and women in general would react to a series of hypothetical emotional events. In Study 2 we asked how participants themselves expected to react to these same situations and in Study 3 (...) we asked participants to report a personal emotional event in narrative form. Two gender differences emerged across all three studies. Specifically, women were expected to be more likely to react with sadness to negative emotion-eliciting events in general. They also expected themselves to be more likely to react with sadness as well as to cry and to withdraw more when experiencing negative emotional events. Finally, women report more sadness when describing personal events. In contrast, men were expected to react with more happiness/serenity during negative emotional situations. Also, they expect themselves to react more frequently this way as well as to laugh and smile more and to be more relaxed in negative situations. Finally, men tend to report more happiness when describing negative personal events. In sum, the present study gives a more detailed portrayal of how men and women are expected and expect themselves to react to specific emotional situations and presents some evidence that these expectations may influence the way they reconstruct emotional events from their past. (shrink)

Developing countries face numerous barriers to conducting effective and efficient ethics reviews of international collaborative research. In addition to potentially overlooking important scientific and ethical considerations, inadequate or insufficiently trained ethics committees may insist on unwarranted changes to protocols that can impair a study's scientific or ethical validity. Moreover, poorly functioning review systems can impose substantial delays on the commencement of research, which needlessly undermine the development of new interventions for urgent medical needs. In response to these concerns, the Drugs (...) for Neglected Diseases Initiative, an independent nonprofit organization founded by a coalition of public sector and international organizations, developed a mechanism to facilitate more effective and efficient host country ethics review for a study of the use of fexinidazole for the treatment of late stage African Trypanosomiasis. The project involved the implementation of a novel ‘pre-review’ process of ethical oversight, conducted by an ad hoc committee of ethics committee representatives from African and European countries, in collaboration with internationally recognized scientific experts. This article examines the process and outcomes of this collaborative process. (shrink)

New concepts may prove necessary to profit from the avalanche of sequence data on the genome, transcriptome, proteome and interactome and to relate this information to cell physiology. Here, we focus on the concept of large activity-based structures, or hyperstructures, in which a variety of types of molecules are brought together to perform a function. We review the evidence for the existence of hyperstructures responsible for the initiation of DNA replication, the sequestration of newly replicated origins of replication, cell division (...) and for metabolism. The processes responsible for hyperstructure formation include changes in enzyme affinities due to metabolite-induction, lipid-protein affinities, elevated local concentrations of proteins and their binding sites on DNA and RNA, and transertion. Experimental techniques exist that can be used to study hyperstructures and we review some of the ones less familiar to biologists. Finally, we speculate on how a variety of in silico approaches involving cellular automata and multi-agent systems could be combined to develop new concepts in the form of an Integrated cell (I-cell) which would undergo selection for growth and survival in a world of artificial microbiology. (shrink)