La discussion sur la doctrine trinitaire d'Origène entraîne nécessairement des questions sur sa pneumatologie. Comme en ce qui concerne le Fils, Origène considère l'Esprit à partir de l'invisible Déité. Il s'appuie sur une logique du Logos : la théologie du Fils est normative pour celle de l'Esprit. Comme l'Eglise pré-nicéenne en général, Origène a un vocabulaire hérétique qui subordonne les trois personnes de la Trinité mais les textes en question sont davantage économiques qu'ontologiques. Selon lui, l'Esprit a-t-il un rôle inférieur (...) au Logos ? Sa pneumatologie est-elle trinitaire ? L'article tente une réponse à ces questions. (shrink)

Extrapolation from a well-understood base population to a less-understood target population can fail if the base and target populations are not sufficiently similar. Differences between laboratory mice and humans, for example, can hinder extrapolation in medical research. Mice that carry a partial or complete human physiological system, known as humanized mice, are supposed to make extrapolation more reliable by simulating a variety of human diseases. But what justifies our belief that these mice are similar enough to their human counterparts to (...) simulate human disease? I argue that, unless three requirements are met in the process of humanizing mice, very little does. My requirements are not meant to provide necessary and sufficient conditions that guarantee a particular outcome. Instead, they serve as a heuristic for guiding scientific judgments involving extrapolation. In developing each requirement, I engage with philosophical issues concerning the nature of model-based science and the mechanistic approach (and its limits) to making generalizations in the life sciences. (shrink)

Our daily lives unfold continuously, yet our memories are organised into distinct events, situated in a specific context of space and time, and chunked when this context changes (at event boundaries). Previous research showed that this process, termed event segmentation, enhances object-context binding but impairs temporal order memory. Physiologically, peaks in pupil dilation index event segmentation, similar to emotion-induced bursts of autonomic arousal. Emotional arousal also modulates object-context binding and temporal order memory. Yet, these two critical factors have not been (...) systematically studied together. To address this gap, we ran a behavioural experiment using a paradigm validated to study event segmentation and extended it with emotion manipulation. During encoding, we sequentially presented greyscale objects embedded in coloured frames (colour changes defining events), with a neutral or aversive sound. During retrieval, we tested participants’ memory of temporal order memory and object-colour binding. We found opposite effects of emotion and event segmentation on episodic memory. While event segmentation enhanced object-context binding, emotion impaired it. On the contrary, event segmentation impaired temporal order memory, but emotion enhanced it. These findings increase our understanding of episodic memory organisation in laboratory settings, and potentially in real life with perceptual changes and emotion fluctuations constantly interacting. (shrink)

The notion of empathy has been explicated in different ways in the current debate on how to understand others. Whereas defenders of simulation-based approaches claim that empathy involves some kind of isomorphism between the empathizer’s and the target’s mental state, defenders of the phenomenological account vehemently deny this and claim that empathy allows us to directly perceive someone else’s mental states. Although these views are typically presented as being opposed, I argue that at least one version of a simulation-based approach—the (...) account given by de Vignemont and Jacob—is compatible with the direct-perception view. My argument has two parts: My first step is to show that the conflict between these accounts is not—as it seems at first glance—a disagreement on the mechanism by which empathy comes about. Rather, it is due to the fact that their proponents attribute two very different roles to empathy in understanding others. My second step is to introduce Stein’s account of empathy. By not restricting empathy to either one of these two roles, her process model of empathy helps to see how the divergent intuitions that have been brought forward in the current debate could be integrated. (shrink)

The exhibition is proposing a different reading of the legal text, reading against the grain of pre-conceived structures in order to re-chart the system of our relations with ourselves and with various communities; both territorial communities as well as those constructed ad hoc, based not on blood or territorial ties, but on shared values and beliefs. The exhibition raises the question of how the law literally produces us: both as individuals and as citizens, establishing a framework of our presence in (...) public space as well - its legality or illegality. It also questions the different meanings of a 'civil body', a 'legal thing', or a 'legal slave'. How do legal rituals and narratives influence and shape our existence? Exhibition: Neue Gesellschaft für bildende Kunst, Berlin, Germany (09.03. - 07.05.2017). (shrink)

Philodemus' History of the Academy represents a valuable treatise on Greek philosophical schools containing much unique information on Plato and on the development of the Academy under his successors. The so called Index Academicorum is a draft version preserved in a Herculaneum papyrus, which has been reread and reedited on the basis of innovative papyrological criteria and pioneering imaging techniques. The text is now very different from former editions and reveals countless new facts on various Academic philosophers. The edition and (...) the commentary provide new insights of interdisciplinary relevance into ancient philosophy, biography, literature and the ancient process of writing a book. (shrink)

The current study investigated age differences in the use of attentional deployment, positive reappraisal and suppression while regulating responses to sadness-eliciting content. We also tested to what extent these emotion regulation strategies were useful for each age group in managing response to age-relevant sad information. Forty-two young participants (Mage = 18.5, SE =.15) and 48 older participants (Mage = 71.42, SE = 1.15) watched four sadness-eliciting videos (about death/illness, four to five minutes long) under four conditions—no-regulation (no regulation instructions), attentional (...) deployment (divert attention away), positive reappraisal (focus on positive outcomes) and suppression (conceal emotional expressions). We assessed negative emotional experience, expression, skin conductance level (SCL) and visual fixation duration while participants watched the emotional clips and followed the instructions for each condition. Results suggest that older adults were more successful than younger adults at implementing both attentional deployment and positive reappraisal. Ability to suppress emotions appears to remain stable with age. Within age-group comparisons suggested that for the older adults, positive reappraisal was a more useful emotion regulation strategy than the others, while the pattern among younger adults was less conclusive. Age-relevant differences in motivation and successful emotion regulatory efforts based on theoretical and empirical literatures are discussed. (shrink)

What’s the basis for considering an egg donor a genetic parent but not a mitochondrial donor? I will argue that a closer look at the biological facts will not give us an answer to this question because the process by which one becomes a genetic parent, i.e., the process of reproduction, is not a concept that can be settled by looking. It is, rather, a concept in need of philosophical attention. The details of my argument will rest on recent developments (...) in biological technology, but the persuasiveness of my argument will turn on the history of another biological concept, death. Given some important similarities between the two concepts, the way in which ‘death’ evolved in the recent past can provide guidance on how we should think about ‘reproduction.’. (shrink)

Research ethics committees must sometimes deliberate about objects that do not fit nicely into any existing category. This is currently the case with the “gastruloid,” which is a self-assembling blob of cells that resembles a human embryo. The resemblance makes it tempting to group it with other members of that kind, and thus to ask whether gastruloids really are embryos. But fitting an ambiguous object into an existing category with well-worn pathways in research ethics, like the embryo, is only a (...) temporary fix. The bigger problem is that we no longer know what an embryo is. We haven’t had a non-absurd definition of ‘embryo’ for several decades and without a well-defined comparison class, asking whether gastruloids belong to the morally relevant class of things we call embryos is to ask a question without an answer. What’s the alternative? A better approach needs to avoid what I’ll refer to as “the potentiality trap” and, instead, rely on the emergence of morally salient facts about gastruloids and other synthetic embryos. (shrink)

In diesem Aufsatz vertrete ich die These, dass die Betreuungsverbote und einschränkungen für Kleinkinder, die im Zuge der Corona-Pandemie in Deutschland galten und immer noch gelten, in bestimmten Fällen zu signifikanten Verlusten des Wohlergehens von Kleinkindern führen. Dabei beziehe ich mich auf Kleinkinder, die in Strukturen leben, in denen die außerhäusliche Betreuung einen gewichtigen Beitrag zur Kinderbetreuung leistet. Ich werde dafür argumentieren, dass für diese Kinder der Wegfall der Kinderbetreuung bedeuten kann, dass gewichtige aktuelle immaterielle Wohlergehensinteressen nur noch teilweise oder (...) gar nicht mehr befriedigt werden. Um diese Interessen und das Ausmaß ihrer Nichtbefriedigung zu beschreiben, greife ich auf das Konzept der Kindheitsgüter zurück und werde mich dabei auf drei gewichtige immaterielle Wohlergehensinteressen konzentrieren: das Interesse des Kindes an pädagogisch wertvollen Betreuungsstrukturen, das Bedürfnis des Kindes nach Austausch und Spiel mit Gleichaltrigen und das Interesse des Kindes, frei von Sorgen und Ängsten zu sein. Die anschließende kinderethische Auswertung dreier aktueller Studien zur Situation der Kinder und Familien unter den Bedingungen der Corona-Pandemie zeigt, dass besonders die Umstände während des Lockdowns im Frühjahr 2020, aber auch die fortbestehenden Einschränkungen bei der Kinderbetreuung sowie die veränderte Arbeitssituation der Eltern erheblich dazu beitragen, dass das Wohlergehen von Kleinkindern in dieser Hinsicht beeinträchtigt wird. Am Ende des Aufsatzes werde ich mich der Frage widmen, was bei der Ausgestaltung zukünftiger Maßnahmen zur Bekämpfung der Corona-Pandemie aus kinderethischer Perspektive berücksichtigt werden sollte, um das Wohlergehen der Kleinkinder so gut wie möglich zu schützen. (shrink)

Die Studien und Texte zur Sozialgeschichte der Literatur (STSL)veröffentlichen seit 1975 herausragende literatur-, geschichts- und kulturwissenschaftliche Arbeiten zur vornehmlich deutschen Literatur vom Mittelalter bis zur Gegenwart. Schwerpunkt der literaturgeschichtlichen und theoretischen Abhandlungen sowie der Quellen- und Materialienbände ist das Verhältnis von literarischem Text und gesellschaftlich-historischem Kontext. Als maßgebliche Publikationsreihe einer seit den 1960er Jahren einflussreichen Sozialgeschichte der Literatur prägt STSL zugleich die literaturwissenschaftliche Diskussion über mögliche Austauschbeziehungen zwischen Literatur-, Geschichts- und Sozialwissenschaften.

It has become increasingly common to talk about the second person in the theory of mind debate. While theory theory and simulation theory are described as third person and first person accounts respectively, a second person account suggests itself as a viable, though wrongfully neglected third option. In this paper I argue that this way of framing the debate is misleading. Although defenders of second person accounts make use of the vocabulary of the theory of mind debate, they understand some (...) of the core expressions in a different way. I will illustrate this claim by focusing on Reddy’s and Gallagher’s accounts and argue that these authors use the notions of knowing and of understanding other minds differently than traditionally assumed. As a consequence, second person accounts thus conceived do not directly address the questions that gave rise to the theory of mind debate. They invite us, however, to critically reflect upon the way the debate has been set up. (shrink)

In the digital age, the use of advanced technology is becoming a new paradigm in police work, criminal justice, and the penal system. Algorithms promise to predict delinquent behaviour, identify potentially dangerous persons, and support crime investigation. Algorithm-based applications are often deployed in this context, laying the groundwork for a ‘smart criminal justice’. In this qualitative study based on 32 interviews with criminal justice and police officials, we explore the reasons why and extent to which such a smart criminal justice (...) system has already been established in Switzerland, and the benefits perceived by users. Drawing upon this research, we address the spread, application, technical background, institutional implementation, and psychological aspects of the use of algorithms in the criminal justice system. We find that the Swiss criminal justice system is already significantly shaped by algorithms, a change motivated by political expectations and demands for efficiency. Until now, algorithms have only been used at a low level of automation and technical complexity and the levels of benefit perceived vary. This study also identifies the need for critical evaluation and research-based optimization of the implementation of advanced technology. Societal implications, as well as the legal foundations of the use of algorithms, are often insufficiently taken into account. By discussing the main challenges to and issues with algorithm use in this field, this work lays the foundation for further research and debate regarding how to guarantee that ‘smart’ criminal justice is actually carried out smartly. (shrink)

Deux assomptions ont été faites au sujet du refus du Pape Pie XII à aller au-delà de condamnations génériques de l'Holocauste Nazi. 1. La politique était dictée par peur de représailles contre les Catholiques et les Juifs. 2. La peur de représailles contre les Juifs était essentiellement une excuse pour ne rien faire ou rester au niveau de condamnations génériques. Mais les organisations juives elles-mêmes ont souvent cité la peur de représailles contre les Juifs comme la raison d'une restrainte dans (...) les déclarations publiques. Bien que la peur des représailles fut un élément formatif de la politique diplomatique du Vatican, la politique n'est pas venue de la peur, comme on peut le voir de l'histoire de condamnations génériques en d'autres contextes de guerre où les atrocités furent en jeu, entre autres en Arménie sous Benoît XV, en Espagne et Abyssinie sous Pie XI, de même qu'en Pologne et en Russie sous Pie XII. Deux fois Benoît XV fit un appel direct au Sultan de Turquie, mentionnant les Arménians spécifiquement trois fois, parlant de «souffrances indicibles», mais sans mentionner des noms personnels, des noms de lieu, des dates, des batailles. Bien que la condamnation resta générique, Benoît XV est considéré un héro national Arménien. Pendant la guerre civile en Espagne les républicains «incontrôlables» ont assassiné plus de cinq mille prêtres, moines et séminaristes pendant les trois premiers mois de la guerre et à la fin de. (shrink)

Much of the book is aimed at persuading the reader that genes are not ‘the prime movers in all biological processes’ and that ‘postgenomic genes’ are better understood in a functional sense, as ‘things an organism can do with its genome.' With the main argument in place, the authors examine its impact on a number of philosophical debates. I will discuss three of them: causation, information, and reduction.

Media reporters often announce that we are on the verge of bringing back the woolly mammoth, even while there is growing consensus among scientists that resurrecting the mammoth is unlikely. In fact, current “de-extinction” efforts are not designed to bring back a mammoth, but rather adaptations of the mammoth using close relatives. For example, Harvard scientists are working on creating an Asian elephant with the thick coat of a mammoth by merging mammoth and elephant DNA. But how should such creatures (...) be classified? Are they elephants, mammoths, or both? Answering these questions requires getting clear about the concept of reproduction. What I hope to show is that with an appropriate notion of reproduction—one for which I will argue—resurrecting a member of Mammuthus primigenius is a genuine possibility. (shrink)

Willing and Understanding elucidates a variety of issues in and approaches to debating the will-intellect interplay in the late Middle Ages. Authored by prominent scholars in the field, the contributions offer different perspectives on the development of late medieval theories of the will. Charting a dense map of voluntarist and epistemological ideas - entrenched leitmotifs of late medieval philosophy, seminal insights sparking original trends, and ephemeral novelties - the volume is a testimony to the conceptual multidimensionality and ethical complexity of (...) the past and present iterations of the debate on the will. Contributors are Pascale Bermon, Magdalena Bieniak, Michael W. Dunne, Riccardo Fedriga, Giacomo Fornasieri, Tobias Hoffmann, Severin V. Kitanov, Monika Michałowska, Riccardo Saccenti, Sonja Schierbaum, Michael Szlachta, Łukasz Tomanek, and Francesco Omar Zamboni. (shrink)

With an increasing number of ways to ‘assist’ reproduction, some bioethicists have started to wonder what it takes to become a genetic parent. It is widely agreed that sharing genes is not enough to substantiate the parent–offspring relation, but what is? Without a better understanding of the concept of reproduction, our thinking about parent–offspring relations and the ethical issues surrounding them risk being unprincipled. Here, I address that problem by offering a principled account of reproduction—the Overlap, Development and Persistence account—which (...) I believe best captures the meaning of ‘genetic parenthood’. (shrink)

Human embryo models formed from stem cells—known as embryoids—allow scientists to study the elusive first stages of human development without having to experiment on actual human embryos. But clear ethical guidelines for research involving embryoids are still lacking. Previously, a handful of researchers put forward new recommendations for embryoids, which they hope will be included in the next set of International Society for Stem Cell Research guidelines. Although these recommendations are an improvement over the default approach, they are nonetheless unworkable, (...) because they rely on a poorly conceived notion of an embryoid’s ‘potential’ to trigger stringent research regulations. (shrink)

New discoveries are improving the odds of human cells surviving in host animals, prompting regulatory and funding agencies to issue calls for additional layers of ethical oversight for certain types of human–animal chimeras. Of interest are research proposals involving chimeric animals with humanized brains. But what is motivating the demand for additional oversight? I locate two, not obviously compatible, motivations, each of which provides the justificatory basis for paying special attention to different sets of human–animal chimeras. Surprisingly, the sets of (...) animals that actually get flagged for special scrutiny by research and funding guidelines do not correlate with either of the sets of animals that arise when we think about what is motivating additional oversight. What this shows is that existing research policies and funding guidelines are disconnected from their motivation: the rationale for flagging certain types of human–animal chimeras as requiring special oversight is ignored in execution. (shrink)

Human–nonhuman chimeras have been the focus of ethical controversies for more than a decade, yet some related issues remain unaddressed. For example, little has been said about the relationship between the origin of transferred cells and the morally relevant capacities to which they may give rise. Consider, for example, a developing mouse fetus that receives a brain stem cell transplant from a human and another that receives a brain stem cell transplant from a dolphin. If both chimeras acquire morally relevant (...) capacities as a result of transplantation, and if those capacities are indistinguishable, should the difference in cell origin matter to how we classify these creatures? I argue that if morally relevant capacities are easy to detect, cell origin is irrelevant to how the chimera ought to be treated. However, if such capacities are hard to detect, cell origin should play a role in considerations about how to treat the chimera. (shrink)

Tato studie se věnuje rané fázi mikroskopického zkoumání přírody Antoni van Leeuwenhoeka, které představil ve své korespondenci členům Royal Society. Studie se zaměřuje na období od navázání styku s Royal Society až do roku 1680, kdy byl Leeuwenhoek zvolen členem společnosti. Z metodologického hlediska studie uplatňuje na Leeuwenhoekovy dopisy členům Royal Society přístup, který představili autoři Steven Shapin a Simon Schaffer v knize Leviathan and the Air-Pump. Pokouší se zjistit, jestli se v Leeuwenhoekových dopisech objevují tři strategie,, které Shapin a (...) Schaffer přisoudili Robertu Boylovi. Studie potvrzuje, že závěry britských autorů platí i pro jiné vědce. (shrink)

Anthropologie und Moralphilosophie wurden von Kant ausfuhrlicher und differenzierter behandelt als bisher angenommen. Daruber hinaus sind beide Disziplinen notwendig voneinander abhangig und aufeinander bezogen. Seine Konzeption des Verhaltnisses von Anthropologie und Moralphilosophie weist Kant aus als wurdigen Gesprachspartner in der modernen Anthropologie- und Moralphilosophie-Diskussion.".