We applaud Notini and colleagues for highlighting the clinical and ethical complexities of a case in which a non-binary individual desires indefinite treatment with puberty blockers.1 While we agree discontinuing treatment may cause psychological distress, we believe there are potential physical and neurocognitive harms caused by prolonged treatment that have been underestimated given the limited research conducted to date. Specifically, the impact of permanent pubertal suppression on the brain and decision-making capacity should be considered. In this context, we outline the (...) potential risks of ongoing pubertal suppression on bone and cardiovascular health, sexual and reproductive function, and brain development—all noted in the article but perhaps in an overly simplistic manner.1 First, the authors’ note OPS will almost certainly result in reduced bone density.1 Although we agree the absolute fracture risk is low in studies among older adults, there is less clarity about implications during adolescence and young adulthood when peak bone accrual occurs.2 Further, the authors propose ongoing monitoring with bone density scans, but no clear guidelines for clinicians if bone density becomes critically low—so we ask, at what point would a potential fracture risk outweigh the proposed benefits …. (shrink)

We applaud Notini and colleagues for highlighting the clinical and ethical complexities of a case in which a non-binary individual desires indefinite treatment with puberty blockers. 1 While we agree discontinuing treatment may cause psychological distress, we believe there are potential physical and neurocognitive harms caused by prolonged treatment that have been underestimated given the limited research conducted to date. Specifically, the impact of permanent pubertal suppression on the brain and decision-making capacity should be considered. In this context, we outline (...) the potential risks of ongoing pubertal suppression on bone and cardiovascular health, sexual and reproductive function, and brain development—all noted in the article but perhaps in an overly simplistic manner. 1 First, the authors’ note OPS will almost certainly result in reduced bone density. 1 Although we agree the absolute fracture risk is low in studies among older adults, there is less clarity about... (shrink)

Are color adjectives ("red", "green", etc.) relative adjectives or absolute adjectives? Existing theories of the meaning of color adjectives attempt to answer that question using informal ("armchair") judgments. The informal judgments of theorists conflict: it has been proposed that color adjectives are absolute with standards anchored at the minimum degree on the scale, that they are absolute but have near-midpoint standards, and that they are relative. In this paper we report two experiments, one based on entailment patterns (...) and one based on presupposition accommodation, that investigate the meaning of scalar adjectives. We find evidence confirming the existence of subgroups of the population who operate with different standards for color adjectives. The evidence of interpersonal variation in where standards are located on the relevant scale and how those standards can be adjusted indicates that the existing theories of the meaning of color adjectives are at best only partially correct. We also find evidence that paradigmatic relative adjectives ("tall", "wide") behave in ways that are not predicted by the standard theory of scalar adjectives. We discuss several different possible explanations for this unexpected behavior. We conclude by discussing the relevance of our findings for philosophical debates about the nature and extent of semantically encoded context sensitivity in which color adjectives have played a key role. (shrink)

It is a consequence of both Kennedy and McNally’s typology of the scale structures of gradable adjectives and Kennedy’s :1–45, 2007) economy principle that an object is clean just in case its degree of cleanness is maximal. So they jointly predict that the sentence ‘Both towels are clean, but the red one is cleaner than the blue one’ :259–288, 2004) is a contradiction. Surely, one can account for the sentence’s assertability by saying that the first instance of ‘clean’ is used (...) loosely: since ‘clean’ pragmatically conveys the property of being close to maximally clean rather than the property of being maximally clean, the sentence as a whole conveys a consistent proposition. I challenge this semantics–pragmatics package by considering the sentence ‘Mary believes that both towels are clean but that the red one is cleaner than the blue one’. We can certainly use this sentence to attribute a coherent belief to Mary: One of its readings says that she believes that the towels are clean by a contextually salient standard ; the other says that she believes that the towels are clean by her own standard. I argue that Kennedy’s semantics–pragmatics package can’t deliver those readings, and propose that we drop the economy principle and account for those readings semantically by assigning to the belief sentence two distinct truth conditions. I consider two ways to deliver those truth-conditions. The first one posits world-variables in the sentence’s logical form and analyzes those truth-conditions as resulting from two binding possibilities of those variables. The second one proposes that the threshold function introduced by the phonologically null morpheme pos is shiftable in belief contexts. (shrink)

Van Selst and Merikle argued that the critical Preference × Strategy interaction findings could be alternatively explained by positing individual differences as a function of preference and strategy. They further argued that ruling out conscious perception depends on making the exhaustiveness assumption. We argue that the inhibitory effects satisfy objective threshold criteria regardless of possible individual differences in thresholds. We further suggest that the inhibitory findings are inherently incompatible with the conscious perception explanation and that therefore we do not (...) need to make the exhaustiveness assumption. We thus stand by our original conclusion that subliminal perception at the objective threshold has been demonstrated. (shrink)

In light of the recent revival of the debate on radical democracy, this paper seeks to show how a critical reappropriation of Chantal Mouffe’s theory of agonistic politics can explain the structure of a conflict-based understanding of democratic orders. In explicit convergence with Mouffe, I argue that a radical democratic project by no means needs to abandon—as many absolute democracy and multitude theorists claim—the modern political paradigm. I also show, diverging from her account, that Mouffe’s defence of a radical (...) democratic project based on pluralism and agonism would have been better served by a critical reception of Arendt’s thinking rather than that of Schmitt. The relevance of this alternative strategy—so I will argue—lies in the fact that it delivers an apt design for a politico-legal order which permits true and proper conflicts, on the one hand, while simultaneously allowing that they be dealt with democratically, on the other. (shrink)

Minors are generally considered incompetent to provide legally binding decisions regarding their health care, and parents or guardians are empowered to make those decisions on their behalf. Parental authority is not absolute, however, and when a parent acts contrary to the best interests of a child, the state may intervene. The best interests standard is the threshold most frequently employed in challenging a parent''s refusal to provide consent for a child''s medical care. In this paper, I will argue (...) that the best interest standard provides insufficient guidance for decision-making regarding children and does not reflect the actual standard used by medical providers and courts. Rather, I will suggest that the Harm Principle provides a more appropriate threshold for state intervention than the Best Interest standard. Finally, I will suggest a series of criteria that can be used in deciding whether the state should intervene in a parent''s decision to refuse medical care on behalf of a child. (shrink)

The paper analyses A.F. Losev''s argument forthe identity of dialectical and mythicalthinking which forms the key part of his theoryof absolute mythology. Losev claims thatdialectical thinking is limited byphenomenological intuition. He fails torecognise, however, that this intuition itselfis a product of thinking. The same is true ofLosev''s concept of `life'' that is designed tolimit intellectual reflection. The mystery ofthe Absolute is, contrary to Losev''s claim, nota threshold that dialectical thinking cannotcross, but it is, in fact, realised only (...) bysuch thinking. This has a bearing on theChristian Neoplatonist doctrine of energisticsymbolism, which also plays a crucial part inLosev''s philosophy of myth. Under the pressureof the Neoplatonist tradition Losev violatesthe demands of dialectical thinking in favourof myth''s essential mysticism. And yet, becauseof the dialectical relation between rationalismand mysticism, Losev''s attempt was not afailure, but a valuable contribution to thetask of illuminating this relation. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Buddhist-Christian Studies 21.1 (2001) 144-147 [Access article in PDF] Book Review Welcoming Flowers from Across the Cleansed Threshold of Hope: An Answer to the Pope's Criticism of Buddhism Welcoming Flowers from Across the Cleansed Threshold of Hope: An Answer to the Pope's Criticism of Buddhism. By Thinley Norbu. New York: Jewel Publishing House, 1997. 93 pp. Welcoming Flowers is a short and tightly written critique of the (...) Buddhism chapter of Pope John Paul II's 1994 best-seller, Crossing the Threshold of Hope. It is a strong, barbed, personal essay from a highly respected Buddhist teacher who expresses shock and dismay that the Pope's actual words about Buddhism that are read as absolute truth by millions of people around the world had "serious, gratuitous misrepresentations of Buddhist doctrine."The book is ostensibly a response to requests from Polish readers and a Polish publishing company to comment on "what the Pope clearly said about Buddhism." The author of Welcoming Flowers, Thinley Norbu, paints himself as a kind of efficient, spiritual cleaning maid who, with tongue in cheek despite his long admiration for the Catholic leader, has to tidy up after the Vicar of Rome: "It is as though the Pope suddenly vomited insolently and uncontrollably in a cathedral, so I hastily had to clean it up, as the Polish people asked me to do."The Pope's negative assessment of Buddhism inspired Thinley Norbu to match [End Page 144] his attack with even more exalted teachings of the Buddha: "I am grateful to the Pope for being like a hit-hitting drumstick that has given me the good opportunity to be like a drum myself, resonating with the sound of profound Dharma. I am grateful to the Pope for yelling with negative words in a valley, letting me return the answer of its transformation into the positive echo of Buddhist hymns."Thinley Norbu in fact uses the Pope's chapter to clarify some basic teachings of Vajrayana Buddhism and how it differs from Mahayana and Hinayana (note: Norbu's term, not this reviewer's) in a concise and instructive manner from the point of view of a practitioner. In this regard,Welcoming Flowers can be considered a kind of introductory, primary source ofTibetan (Nyingma)Vajrayana Buddhist doctrine for those who are unfamiliar with the various schools of Buddhism. The Pope's seriously outdated (reminiscent of Max Weber or early missionaries), limited, and unsympathetic understanding of one school of Buddhism is used by Thinley Norbu as a platform to expound his rich understanding of Buddhist traditions toWestern readers of comparative religion and specifically to Catholics. The book's twenty-nine footnotes can also function as a brief glossary of transliterated TibetanVajrayana Buddhist terms (but without use of diacritical marks for Sanskrit or Pali terms).Thinley Norbu is careful to mitigate his condemnation of the Pope's unwarranted ignorance of Buddhism by sharing the onus with the Pope's not-so-sapient preceptors. He generously suggests that the Pope may not bear all the blame for the chapter's shortcomings in the following paragraph: The misrepresentations of Buddhism in his book may have come from listening to advisors who were unfamiliar with Buddhism, from simply glancing at books at the Hinayana level, or by being shown books by misinformed authors. Perhaps he only looked at negative conceptions about Buddhism written by followers of other doctrines who had malicious intentions, or by idiots who wrote books for money without caring that they were full of mistakes. In any case, the Pope definitely heard about Buddhism from sources that did not know anything about it. It seems... as though he... scooped a few drops of water from an immeasurable ocean with a piece of grass and even misunderstood these few drops (p. 2). Norbu reprimands the Pope for not doing his required homework, a fault that can lead to serious disharmony among religions."Without studying and understanding other doctrines deeply, to say many things about them is not wise," Norbu continues; "it... (shrink)

Satisficing theories, whether of rationality or morality, do not require agents to maximize the good. They demand only that agents bring about outcomes that are, in one or both of two senses, “good enough.” In the first sense, an outcome is good enough if it is above some absolute threshold of goodness; this yields a view that I will call absolute-level satisficing. In the second sense, an outcome is good enough if it is reasonably close to the (...) best outcome the agent could bring about; this leads to what I will call comparative satisficing. These two views coincide in their implications for a specific sort of case, in which the situation is now fairly far below the absolute-level threshold and an agent can at best bring it to a point somewhat above that threshold. Here both absolute-level and comparative satisficing say he need not bring about his best available outcome, though of course he may; he is required only to improve the situation to the absolute threshold. But in other cases the views diverge. If the situation is now far below the absolute threshold and, no matter what, will remain below it, absolute-level satisficing requires an agent to everything he can to improve the situation; here its implications coincide with those of maximizing. But comparative satisficing is less demanding, requiring him only to make some reasonable percentage of the largest improvement he can. By contrast, if the situation is already above the absolute threshold, absolute-level satisficing does not require an agent to do anything at all to improve it, whereas comparative satisficing, which is now more demanding, still requires him to make some reasonable percentage of his best possible improvement. (shrink)

In this paper I examine the prospects for a rights-based approach to the morality of pure risk-imposition. In particular, I discuss a practical challenge to proponents of the thesis that we have a right against being imposed a risk of harm. According to an influential criticism, a right against risk-imposition will rule out all ordinary activities. The paper examines two strategies that rights theorists may follow in response to this “Paralysis Problem”. The first strategy introduces a threshold for when (...) a risk-imposition is a rights violation. The second strategy drops the claim that rights are absolute and maintains that all rights infringements generate compensation duties. It is argued that both strategies face significant practical problems of their own and that the Paralysis Problem seems fatal for a right against risk-imposition in the absence of an adequate account of the morally relevant threshold risk. (shrink)

An epistemological orthodox view holds that knowing that p is an absolute ‘yes-or-no’ affair rather than something that comes in degrees. The rising epistemic gradualist theory challenges this orthodoxy by arguing that knowledge-that is a gradable concept. The predominant form of argument for gradualism in the current literature is the argument from component, according to which knowledge is gradable because its various components (e.g., justification, belief, truth) are gradable. I will show that the argument from components involves a non-sequitur: (...) the alleged gradability of knowledge’s components cannot ensure the gradability of knowledge per se. The crux of this logical lacuna lies in that the argument neglects the external gradability of knowledge, viz, there is no clear-cut threshold between knowledge and lack thereof. The lacuna can be mended by seeing knowledge-that as a spectrum concept such that a more complete gradualist picture can be achieved. (shrink)

Free-will incompatibilism has become a motte-and-bailey doctrine (Shackel 2014), and is currently being maintained by standard motte-and-bailey strategies. In this paper, I explain why incompatibilism has a motte-and-bailey structure and why philosophers who do not aim to dismantle it are complicit in both the maintenance of this problematic doctrine and the normalization of a host of bad practices engaged in by those who actively exploit it. To solidify the diagnosis, I provide a paradigmatic motte-and-baileying case that has been ongoing for (...) over a decade. Specifically, I discuss how motte-and-baileying has generated widespread confusion surrounding the logical structure and conclusion of manipulation arguments. Even more specifically, I look at Mele's so-called "Zygote Argument for incompatibilism". I point out that Mele currently conflates under two distinct arguments with different logical forms and substantively different conclusions under that heading, and explain how this has needlessly impeded progress in the free-will debate. The original variant of the Zygote Argument was invalid because it aimed to establish that determinism precludes (destroys, undermines, is antagonistic to) free will, but its supported a far weaker non-explanatory conclusion. In direct response to this invalidity objection, Mele took his critic's suggestion to change the conclusion of his argument to the thesis that free will and determinism are perhaps spuriously associated -- but he also covertly changed his preferred definition of 'incompatibilism' to pick out the non-explanatory conclusion of the new variant of the Zygote Argument which allowed him to continue speaking AS IF his argument was still an argument for incompatibilism according to his original definition of 'incompatibilism'. It is not simply that Mele made these changes or that he failed to mention in print that he made them (despite having over a decade to do so), but that he has actively attempted to discredit his critics by insisting--contrary to fact--that those who do not use his negative definition of 'incompatibilism' are using the term in a nonstandard and nontraditional way that he has "never had any use for" and there is some kind of connection (which he does describe) between the invalidity objection to his original argument that the definition of 'incompatibilism' one prefers. Oddly, Mele has mentioned only one "invalidity objection" in print, but this objection is direct at the revised Zygote Argument--even though no one had ever pressed an invalidity objection to his new argument (the form of which is patently valid). As a direct result of Mele's evasive behaviors (covertly redefining jargon to cover changes to the form/conclusion of his argument), many people--including Mele's own former graduate students--have published articles in which they fail to recognize that Mele changed his argument and redefined terms, thereby perpetuating the false narrative that the new Zygote Argument has the same "incompatibilist" conclusion as the original (which, notably, had the same conclusion as its predecessor, Pereboom's Four-Case Argument). Moreover, Mele has not even ONCE corrected those who "misdescribe" his revised argument as concluding that determinism is antagonstic to (precludes, undermines, rules out, etc.) free will. For example, Mele never corrects those who mistakenly claim that the revised Zygote Argument has the same "incompatibilist" conclusion as Pereboom's, nor has Mele ever mentioned that he now defines the term 'incompatibilism' differently than Pereboom--since Pereboom since uses this term to refer to the explanatory conclusion of the original Zygote Argument, which had the same explanatory conclusion of his Four-Case Argument. To further throttle his critics, Mele has obliquely suggested that the invalidity objection to his original Zygote Argument works only if one accepts his critic's idiosyncratic definition of 'incompatibilism' -- a patently false charge (since the term 'incompatibilism' doesn't even appear in his arguments) and one that has needlessly confused his audience. Indeed, other philosophers have now made this false and quite indefensible accusation explicitly in print, thereby helping Mele and others to continue motte-and-baileying with impunity. I close by preemptively responding to strategies commonly used by motte-and-bailey apologists to suppress legitimate criticisms of their equivocation and well-poisoning strategies (e.g. "Philosophers are allowed to define their technical terms however they like" and "the motte/bailey divide is a distinction without a difference") which have hitherto kept their philosophical audience from participating in a legitimate discussion about why tracking the distinction between the the "motte" thesis (a negative, arguably spurious association claim) and the "bailey" thesis (a positive explanatory claim) is not trivial, but is instead one that is absolutely essential to making progress in the free-will debate. Of course, a single critic cannot (almost by definition) undermine a motte-and-bailey doctrine once it has been established. As such, even if every diagnosis in this essay is accurate, it will not change the discourse. The motte-and-baileying will continue, and the debate will remain in needless deadlock, until a critical threshold of OBSERVERS learn about the motte/bailey distinction and ask apologists for motte-and-bailey incompatibilism to stop their motte-and-baileying. -/- Manuscript available upon request, plz gmail me: kristin.mickelson.42@. (shrink)

Researchers have recently provided proof of concept for uterus transplantation, giving rise to a discussion about priority setting. This article analyses whether absolute uterine‐factor infertility (AUFI), the main indication for uterus transplantation, gives rise to a healthcare need and the extent to which such a need places justified claims on public funding in a needs‐based welfare system. It is argued that, regardless of the concept of health to which one subscribes, there is a healthcare need for uterus transplantation in (...) women with AUFI. The provision of alternative ways of addressing this need, such as surrogacy and adoption, reduces its severity. Hence, where such alternatives are publicly funded, uterus transplantation is unlikely to become cost‐effective. However, where surrogacy and adoption are not publicly funded, uterus transplantation should be given a similar priority level to other assisted reproductive technologies. In these circumstances, public funding for uterus transplants may well be justified, particularly in well‐funded healthcare system with relatively generous cost‐effectiveness thresholds. (shrink)

Classifying research proposals by risk of harm is fundamental to the approval process and the most pivotal risk category in most regulations is that of “minimal risk.” If studies have no more than a minimal risk, for example, a nearly worldwide consensus exists that review boards may sometimes: (1) expedite review, (2) waive or modify some or all elements of informed consent, or (3) enroll vulnerable subjects including healthy children, incapacitated persons and prisoners even if studies do not hold out (...) direct benefits to them. The moral and social purposes behind this threshold are discussed along with relevant views from the National Commission, NBAC, NHRPAC, Grimes v. Kennedy Krieger Institute, The Nuremberg Code, and The WMA's Declaration of Helsinki. Representative policies from Australia, Canada, South Africa, the U.S., and CIOMS are reviewed revealing different understandings of this sorting threshold. Six of nine frequently cited interpretations of “minimal risk” are untenable. The “absolute” interpretation of the “routine examination” standard is defended as best. (shrink)

The article offers an attempt to understand the present state of Kant’s legacy in Russia on the threshold of the Tercentenary. An explanans is found in the metaphors of “ tabula rasa ” and “unplowed virgin soil,” first used by Leibniz in relation to Russia in his letters and memoranda addressed to tsar Peter I and other members of the Russian elite, which became the country’s “absolute metaphors to live by” up to present time. Several known and unknown (...) episodes from the history of the reception of Kantian ideas, his followers in Russia, and the transformation of the urban environment of Kant’s life in Königsberg, as it was becoming Kaliningrad, are presented through the prism of this metaphor. Without hoping to make specific recommendations of any use from such metaphorical grounds, this study aims to emphasize the depth, interconnectedness, and basic, metaphysical tension of the relationship between Europe and Russia, which cannot be terminated at will by either side, or by a third party. In a situation where the sides are doomed to dialog, Kant, appropriated by Russia as its “subject,” occupies the unique position of mediator of philosophical understanding and peaceful action. (shrink)

Ecological economics is an interdisciplinary science that is primarily concerned with developing interventions to achieve sustainable ecological and economic systems. While ecological economists have, over the last few decades, made various empirical, theoretical, and conceptual advancements, there is one concept in particular that remains subject to confusion: critical natural capital. While critical natural capital denotes parts of the environment that are essential for the continued existence of our species, the meaning of terms commonly associated with this concept, such as ‘non-substitutable’ (...) and ‘impossible to substitute,’ require a clearer formulation then they tend to receive. With the help of equations and graphs, this article develops new definite account of critical natural capital that makes explicit what it means for objective environmental conditions to be essential for continued existence. The second main part of this article turns to the question of formally modeling the priority of conserving critical natural capital. While some ecological economists have maintained that, beyond a certain threshold, critical natural capital possesses absolute infinite value, absolute infinite utility models encounter significant problems. This article shows that a relative infinite utility model provides a better way to model the priority of conserving critical natural capital. (shrink)

This paper explores ‘reasonable doubt’ as an enlightening notion to think of reasoning and decision-making generally, beyond the judicial domain. The paper starts from a decision-theoretic understanding of the notion, whereby it can be defined in terms of degrees of belief and a probabilistic confirmation threshold for action. It then highlights some of the limits of this notion, and proposes a richer analysis of epistemic states and reasoning through the lens of ‘reasonable doubt’, which in turn is likely to (...) supplement the DT framework. The strategy consists in fighting on two fronts: with DT, the paper claims that there is no absolute notion of ‘reasonable doubt’ but, pace DT, it shows that reasonable doubt cannot be accounted for only in terms of degrees of belief and probabilistic threshold. We argue that the lens of reasonable doubt sheds light on aspects of belief dynamics, as well as of the nature of epistemic attitudes, which are often obscured by belief-centred approaches. In particular, when it comes to acknowledging the necessary ignorance and irreducible uncertainty that we face in our everyday-life decisions, studying the various facets of doubt rather than focusing on what can be believed, enables one to do justice to the richness and diversity of the mental states in play. (shrink)

Sufficientarians claim that what matters most is that people have enough. I develop and defend a revised sufficientarian conception of justice. I claim that it furnishes the best specification of a general humanitarian ideal of social justice: our main moral concern should be helping those who are badly off in absolute terms. Rival humanitarian views such as egalitarianism, prioritarianism and the difference principle face serious objections from which sufficientarianism is exempt. Moreover, a revised conception of sufficientarianism can meet the (...) most prominent undefeated challenges to the view. I contend that prevailing versions of sufficientarianism have not satisfactorily defined the sufficiency threshold, and so I offer an original specification of the threshold. I also address perhaps the most common objection to sufficientarianism, namely that sufficientarian regimes will channel all of society's resources towards elevating people to the sufficiency threshold regardless of the gains foregone by those above the threshold. (shrink)

This essay makes three claims about preventive war, which is demarcated from preemptive war and is part of a broader class of ?anticipatory? wars. Anticipatory wars, but especially preventive war, are ?hard cases? for traditional Just War theory; other puzzles for this tradition include nuclear deterrence, humanitarian intervention, and provability a priori of the success of Tit-for-Tat. First, and despite strong assertions to the contrary, it is far from clear that preventive war is absolutely prohibited in traditional Just War Theory, (...) and it is also dubious that it is in all cases ?clearly illegal?. Second, the morality of both preemptive and preventive wars is shown to turn on epistemological considerations: on what degree and kind of justification the primary metaphysical facts of threat can be reasonably believed. Third, an argument is made that whatever epistemic threshold is held to be necessary, some preventive wars will exceed it, and that this is more likely with advancing technologies of information acquisition. Finally, the common argument that allowing all nations to follow policies of preventive war would result in more wars than barring such policies is shown to be mistaken by simulations in game theory. Suggestions are made about the derivation of traditional Just War criteria from more basic moral principles, and about their subtle failures as jointly necessary conditions for the morality of war. (shrink)

Why do we not see large macroscopic objects in entangled states? There are two ways to approach this question. The first is dynamic. The coupling of a large object to its environment cause any entanglement to decrease considerably. The second approach, which is discussed in this paper, puts the stress on the difficulty of observeing a large-scale entanglement. As the number of particles n grows we need an ever more precise knowledge of the state and an ever more carefully designed (...) experiment, in order to recognize entanglement. To develop this point we consider a family of observables, called witnesses, which are designed to detect entanglement. A witness W distinguishes all the separable (unentangled) states from some entangled states. If we normalize the witness W to satisfy tr W 1 for all separable states , then the efficiency of W depends on the size of its maximal eigenvalue in absolute value; that is, its operator norm W . It is known that there are witnesses on the space of n qubits for which W is exponential in n. However, we conjecture that for a large majority of n-qubit witnesses W O n log n . Thus, in a nonideal measurement, which includes errors, the largest eigenvalue of a typical witness lies below the threshold of detection. We prove this conjecture for the family of extremal witnesses introduced by Werner and Wolf [Phys. Rev. A 64, 032112 (2001)]. (shrink)

In Alastair Norcross argues that scalar consequentialism is the most plausible form of consequentialism, but his arguments are flawed: he is simply mistaken when he suggests that there is a problem with deriving absolutes like right and wrong from gradable properties such as goodness; he cannot justify his claim that the choice of a threshold will always be arbitrary; and his argument only shows that the consequentialist doesn't care about permissibility. Furthermore, I argue that, although Norcross was right to (...) claim that a scalar theory can be action-guiding (to an extent), he was mistaken to think that ought If anything can be said in favour of scalar consequentialism, it is only that it is the most honest form of consequentialism, because it doesn't pretend to care about permissibility. (shrink)

How demanding is the virtuous life? Can virtue exist alongside hints of vice? Is it possible to be virtuous within a vicious society? A line of thinking running through Diogenes and the Stoics is that even a hint of corruption is inimical to virtue, that participating in a vicious society makes it impossible for a person to be virtuous. One response to this difficulty is to claim that virtue is a threshold concept, that context sets a threshold for (...) what is considered virtuous. On this way of thinking, what counts as virtuous in one society may be more demanding than what passes for virtuous in another. This response seems plausible when considering that virtue-theoretic terms like `honest' are gradable adjectives. Many gradable adjectives, like `tall' and `expensive,' have contextual thresholds that shift depending on the situation, and so is tenable that virtue-theoretic adjectives might function with contextual thresholds as well. A major difficulty for this response, however, is that virtue terms are absolute gradable adjectives, a variety of gradable adjectives that do not require a contextual threshold. Absolute gradable adjectives instead draw their truth conditions from their maximal degree, suggesting that Diogenes and the Stoics were correct to think that virtue is incompatible with even a small degree of vice. (shrink)

Background Doctors sometimes encounter parents who object to prescribed treatment for their children, and request suboptimal substitutes be administered instead. Previous studies have focused on parental refusal of treatment and when this should be permitted, but the ethics of requests for suboptimal treatment has not been explored. Methods The paper consists of two parts: an empirical analysis and an ethical analysis. We performed an online survey with a sample of the general public to assess respondents’ thresholds for acceptable harm and (...) expense resulting from parental choice, and the role that religion played in their judgement. We also identified and applied existing ethical frameworks to the case described in the survey to compare theoretical and empirical results. Results Two hundred and forty-two Mechanical Turk workers took our survey and there were 178 valid responses. Respondents’ agreement to provide treatment decreased as the risk or cost of the requested substitute increased. More than 50% of participants were prepared to provide treatment that would involve a small absolute increased risk of death for the child and a cost increase of US$<500, respectively. Religiously motivated requests were significantly more likely to be allowed. Existing ethical frameworks largely yielded ambiguous results for the case. There were clear inconsistencies between the theoretical and empirical results. Conclusion Drawing on both survey results and ethical analysis, we propose a potential model and thresholds for deciding about the permissibility of suboptimal treatment requests. (shrink)

In this paper, we present a Capabilities -based Approach to the acceptability and the tolerability of risks posed by natural and man-made hazards. We argue that judgments about the acceptability and/or tolerability of such risks should be based on an evaluation of the likely societal impact of potential hazards, defined in terms of the expected changes in the capabilities of individuals. Capabilities refer to the functionings, or valuable doings and beings, individuals are able to achieve given available personal, material, and (...) social resources. The likely impact of a hazard on individuals’ capabilities should, we argue, be compared against two separate thresholds. The first threshold specifies the minimum level of capabilities attainment that is acceptable in principle for individuals to have in the aftermath of a hazard over any period of time. This threshold captures the level that individuals’ capabilities ideally should not fall below. A risk is acceptable if the probability that the attained capabilities will be less than the acceptable level is sufficiently small. In practice, it can be tolerable for some individuals to temporarily fall below the acceptable threshold, provided this situation of lower capabilities attainment is temporary, reversible, and the probability that capabilities will fall below a tolerability threshold is sufficiently small. This second, tolerable threshold delimits an absolute minimum level of capabilities attainment below which no individual in a society should ever fall, regardless of whether that level of capabilities attainment is temporary or reversible. In this paper, we describe and justify this Capabilities -based Approach to the acceptability and tolerability of risks. We argue that the proposed theoretical framework avoids the limitations in current approaches to acceptable risk. The proposed approach focuses the attention of risk analysts directly on what should be our primary concern when judging the acceptability and the tolerability of risks, namely, how risks impact the well-being of individuals in a society. Also, our Capabilities -based Approach offers a transparent, easily communicable way for determining the acceptability and the tolerability of risks. (shrink)

The first obstacle that confronts the student of induction is that of defining the subject matter. One initial point is to note that much of the relevant subject matter goes under the description ‘the theory of confirmation’. The distinction is primarily that the study of induction concerns inference, i.e. cases where one takes the conclusion to be established by the evidence, whereas confirmation concerns the weight of evidence, which one may take to be something like the credibility of a hypothesis (...) in the light of the evidence. Discussions of confirmation often concern incremental confirmation, i.e. cases where the evidence is taken to increase the credibility of some hypothesis, even if not sufficiently to warrant inferring the truth of that hypothesis. However, some uses of ‘confirmation’ clearly refer to absolute confirmation, cases where the credibility of the hypothesis in the light of the evidence exceeds some (high) threshold. One may ask whether inductive inference corresponds to the case of absolute confirmation for some suitable threshold. I shall discuss inference and confirmation together, though it should be noted that some approaches eschew inference altogether. For example, the Bayesian takes scientific reasoning to be a matter of adjusting credences in propositions in the light of evidence, and says nothing about unqualified belief in a proposition. However, if we are interested in inductive knowledge then we must consider inference, since only then do we have a detached proposition that is the possible content of a mental state of knowing. A more pressing question concerns which inferences (or allegedly confirmatory relations) should be classed as inductive. A natural and straightforward approach is to define induction as encompassing any form of reasoning that extrapolates from one population to another, usually from a sample of a population to the whole population. For example, one might note that all observations of the position of some planet fall on an ellipse that has the Sun at one of its foci; from this one concludes that all the positions that planet takes fall on this ellipse (i.e.. (shrink)

Introduction Reza Davari Ardakni, the Iranian contemporary philosopher, distinguishes development from Western modernity; in that it considers modernity as natural and organic changes that Europe has gone through, but sees development as a planned design for implementing modernity in other countries. As a result, the closedness of development concerns only the developing countries, not Western modern ones. Davari emphasizes that the Western modernity has a universality that pertains to a unique reason and a unified world. The only way of thinking (...) in this world is a philosophical thought based on human self-centered reason, and given the pervasiveness of Western civilization. Therefore, Davari does not consider Westernization as mere imitation of Western customs and methods, but rather as a way of existence in the world. Westernization is a subjective view of the world and beings. Westernization is not optional, enabling non-Western people to avoid it. According to the Westernization scenario, the world today is entirely Westernized, and Davari considers Westernization as the inevitable fate of the people of this era, seeing two alternatives for them, both of which ultimately lead to the same destination, which is to embrace development; either they seize the power of science and technology and join the process of global modernization and participate in it, or they become subdued by this process and accept it without participation. Davari regards the first type of Westernization as active and the second type as passive. Problematique Therefore, underdevelopment is not a concept of the ancient world, nor even of a world between the ancient and the modern, or on the threshold of modernization. Underdevelopment is a condition of suspension and timelessness and being exposed to modernization. To escape the paradox of underdevelopment, which is the inevitable historical fate of non-modernized societies, Davari sees no way out other than embracing development. In other words, Westernized societies, which have become confused due to modernization, have no escape route other than turning to development. Therefore, some critics of Davari accuse the theory of Westernization of being a theoretical rupture. M. T. Tabatabaei, by rejecting the theoretical rupture in the theory of Westernization, believes that in the argument of Davari, we are only faced with a shift from a philosophical to an intellectual level. Tabatabaei, by avoiding providing a philosophical response to the critics of the theoretical rupture, believes that the introduction of active Westernization and collaboration in science and technology as a solution to escape from underdevelopment conditions, is only a shift from a philosophical level to an intellectual level and does not involve a rupture. Therefore, it seems that the philosophical issue of how or the possibility of escaping from underdevelopment conditions is still an open non answered problem. In this study, seeking a philosophical answer to this problem, an attempt has been made to summarize Davari's definitions of development, underdevelopment, participation in the world of science, and the role of humanities and social sciences in development, using his writings and speeches. It is proposed that a way to escape from the clesedness of development based on Davari's views, is to make use of analytical method with emphasizing on concepts and theories of the philosophy and metaphysics of science. Argument According to Davari, the social and human sciences that are responsible for development planning in underdeveloped societies must consider the characteristics of underdevelopment in order to facilitate the transition to more favorable conditions. Davari identifies the following conditions for successful development: 1) replacing tradition with science as the organizing and coordinating principle in society, 2) recognizing the universality of philosophy and science of the Western modernity and the impossibility of blindly imitation and adopting it, 3) inevitability of actively engaging and interacting with development, 4) recognizing the internal dynamics of scientific progress and avoiding authoritarian control, and 5) promoting free participation in the scientific paradigms. Therefore, Davari suggests the following steps towards development: 1) recognizing and understanding the problems of society and the local ecosystem, 2) understanding the philosophical and cultural foundations of Western civilization, 3) understanding the historical context and paradigms of science, 4) understanding the philosophical and metaphysical foundations of science, 5) recognizing the intellectual and philosophical capacities of our own community, and 6) reflecting our own philosophical and metaphysical assumptions in the scientific world in a way that is compatible with scientific methods. Given the motivations for change in science at both the global and national levels, including the emergence of heterodox or indigenous sciences, and the inevitable nature of development, Davari points to the possibility of a path between absolute rejecting or accepting the mainstream social and human sciences. However, this path is challenging and contingent upon the aforementioned conditions and steps of transition. Conclusion It is necessary to seek this path within the realm of the philosophy and metaphysics of science, particularly in the origins and foundations of the social and human sciences. Research in the metaphysics and philosophy of the social sciences provides the opportunity for active scientific engagement in the scientific paradigms and a reconsideration of the foundations of science, allowing for different philosophical foundations while are compatible with scientific methods. Successfully finding a path between absolute rejecting or accepting the existing social sciences will lead to an internal transformation within the field of science and, in fact, will advance the boundaries of knowledge. Therefore, it is possible, while adhering to the conditions of transition and actively participating in the world of science and technology, and accepting the unity of modernity and avoiding selectivity and imitation, to search for a way to overcome the closedness of development through a reconsideration of the philosophical and metaphysical foundations of science, while recognizing our own intellectual heritage and critically assessing Western science and technology. (shrink)

The form of life is a secret so secret.What does it mean to initiate life? For the Italian philosopher Giorgio Agamben, the question of initiating life concerns how we conceive of and experiment with the how of a form of life. In short, it involves ways of envisaging an absolutely immanent life on the threshold of its political and ethical intensification. Agamben's whole philosophical project can be described as radical mannerism that foregrounds the question of the way of living. (...) To follow Agamben's paradigmatic problematization, an initiated life is thus a life made inextricable from its manner or form—a form-of-life.Initiating life is a complex and multifaceted question. One spontaneous way to approach it is in... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Ideas 62.4 (2001) 577-592 [Access article in PDF] Eclecticism and the History of Ideas Donald R. Kelley "What we call the history of ideas," Joseph Mazzeo wrote in in 1972, "itself has a history." 1 In this country the history of ideas in the past century has been associated with the American philosopher and founder of this journal, Arthur O. Lovejoy, and his epigones (...) and critics. However, this field has an earlier history sub literam, going back almost two centuries, and a still deeper prehistory before the coinage of the phrase, traceable at least indirectly back to antiquity. The purpose of this essay is to trace some aspects of one intellectual tradition out of which the history of ideas has, knowingly or not, emerged.In 1829 Victor Cousin gave a diagnosis of and his prescription for philosophy in the wake of one revolution and on the threshold of another. He saw just three possibilities: either it could renounce its independence and submit again to authority, it could keep on retracing the circle of obsolescent systems, or--and this was his solution--it could "disengage what is true in each of these systems, and thus construct a philosophy superior to all systems [and] shall be neither this or that philosophy in its essence and in its unity." This procedure, "to select in all what appears to be true and good, and consequently everlasting,--this, in a single word, is ECLECTICISM." Moreover, Cousin added, "[i]f this philosophy is to be Eclectic, it must also be sustained by the history of philosophy."How had Cousin come upon this program? In December 1815, in the first year of both the Restoration Monarchy and his teaching at the École Normale Supérieure, he was lecturing on the history of philosophy. In post-revolutionary France this was a field in great disarray, and Cousin looked back to the great schools of the earlier generation, noting three in particular--the French, the [End Page 577] Scottish, and the German traditions, represented respectively by Condillac, Reid, and Kant. "It would be an interesting and instructive study," he told his enthusiastic young students, "to examine the weaknesses of these schools by engaging one with another and by selecting their various merits in the context of a great eclecticism which would contain and surpass all three." 2Over the next three decades this doctrine was publicized and extended by Cousin's many scholarly publications, by the still more famous lectures he gave after returning to his chair of philosophy in 1828, by his many international contacts and disciples, and by his later public career as minister of education. 3 For half a century before his death in 1867 Cousin had an unparalleled intellectual influence as virtually the "official philosopher" in France, with Eclecticism being widely regarded as a "state philosophy," 4 and translations of his works extending his renown into other parts of Europe and this country. In defending his achievements and hegemonic position Cousin claimed an absolute originality and a unique truth-value for his ideas. Eclecticism had not been drawn from German sources, he protested in 1855. "It was born spontaneously in our own spirit [notre esprit] from the spectacle of the resounding conflicts and the hidden harmonies of the three great philosophical schools of the eighteenth century," he declared. "Thus," he concluded, "eclecticism is a French doctrine and peculiar to us." 5Historically speaking, however, nothing could be further from the truth--or indeed further from the premises of the earlier eclectic tradition on which Cousin knowingly drew. The defining characteristic of his philosophy was its dependence not only on the three schools he recognized in his early years of teaching but on the whole history of philosophy from its Greek and especially Platonic beginnings, to which Cousin himself devoted much of his historical and philological [End Page 578] scholarship. That Eclecticism was a sort of higher plagiarism was admitted by Cousin himself: "What I recommend," Cousin said in 1817, "is an enlightened eclecticism which, judging with equity, and even with benevolence... (shrink)

In this paper, I offer a novel interpretation of THN 1.4.7, which sees his sceptical problem and solution in THN 1.4.7 as taking a broadly deontological structure. Briefly, I read the ‘Dangerous Dilemma’ (THN 1.4.7.6-7) as embodying a false dichotomy between two deontological extremes concerning reflection, that is, thinking carefully about our mental states and faculties. The two horns of the Dangerous Dilemma are as follows: either embracing an absolute duty to constantly and incessantly reflect (leading to excessive scepticism); (...) or maintaining that it is not the case that we have any duty to reflect to any degree (leading to credulity). Hume thus seeks to straddle these two horns and find a deontological middle path. The resolution to this dilemma turns on Hume’s realising that we have a duty to reflect only up to a point. Beyond this threshold, there is a level of reflection that is not required of us, but which is nevertheless good; in other words, such reflection is supererogatory. However, this seems to render excessive scepticism supererogatory. This unintuitive outcome can be avoided by appealing to a suitable account of value beyond the deontological threshold that is founded on usefulness and agreeableness. In the end, Hume manages to tread a path between scepticism and credulity, while nevertheless rejecting superstition and endorsing science and philosophy. (shrink)

Lorazepam has been repeatedly shown to induce memory impairments. The effects of this benzodiazepine on the processes involved in the strategic regulation of memory accuracy have not as yet been explored. An experimental procedure that delineates the role of monitoring and control processes was used. Fifteen lorazepam and 15 placebo subjects were examined using a semantic memory task that combined both a forced- and a free-report option and a no-incentive and an incentive condition. Memory accuracy was lower in the lorazepam (...) than in the placebo group. Lorazepam impaired control sensitivity (the extent to which volunteering of answers is affected by the confidence judgments). While the absolute aspect of monitoring was impaired (calibration scores), both the discriminative aspect (the ability to distinguish between correct and incorrect answers) and the response criterion setting (the confidence threshold set for volunteering a report) were spared. The pharmacological dissociation between monitoring effectiveness and control sensitivity indicates that these two components involve distinct processes. (shrink)

In the article, composed of two parts with the titles Spektakl modernistyczny czy seans spirytystyczny? (A modernist spectacle or a spiritistic seance?) and Dlaczego Słowacki niszczy konterfekt księcia Józefa? (Why does Słowacki destroy the portrait of Prince Józef?), presents a contextual interpretation of Jan Lechoń’s poem Duch na seansie (A Ghost at a Seance). The author questions the opinion, which was widespread in literary criticism, that Lechoń together with other members of the Skamander group discredited Romantic poetry and national mythology (...) on the threshold of independence. The analysis of the poem made in the article leads to the conclusion that the poet fought stereotypes deeply rooted in public opinion, which in the eyes of the general public were also reinforced by Slowacki’s poetry. Thus, Słowacki appears at the seance to demystify a belief in the messianic, necrotic and patriotic tone of his poetry, in the bard-creator of the national Gospel, who is endowed with the power to discover absolute truths, and in the „master of the word” as well as the „creator of artistic beauty” as well as the only generally-accepted opinion. Optimistic signs of revival have dominated the symbols of suffering, the talkativeness has been replaced by silence, the word by the iconoclastic deed, the mystical heat by ironic distance. The symbols, images, references to literary texts and other signes of culture help to create a revalued portrait of Słowacki and mould a myth of gray heroism, which is a complete contrast to the myth of the „colourful uhlan”. The destruction of the portrait of Prince Józef Poniatowski and a reference to Piłsudski found in the last line of Karmazynowy poemat (The Crimson Poem) are the signs of the ideological declaration of the young poet, who referring to great Romantic tradition, discovers new and new meanings. (shrink)

Auf dem Gebiete des Gesichtssinnes gelten an der phänomenalen, absoluten Schwelle die begrifflichen, linearen ReizausdrückeL. t = Konstante bzw.L. f = Konstante, in denenL die physikalische Lichtintensität,t die Reizzeitdauer undf die Reizfläche bedeuten . Der zeitliche Gültigkeitsbereich des erstgenannten Ausdrucks erstreckt sich von ganz kurzen bis zu Zeitdauern von etwa 100σ, d.h. bis zu Zeitdauern die phänomenal eben noch als momentan empfunden werden. Entsprechend scheint sich der Gültigkeitsbereich des zweitgenannten Ausdrucks nur bis zu solchen Flächengrössen zu erstrecken, die phänomenal eben (...) noch als punktuell erscheinen. Bei phänomenal momentanen, punktuellen und minimalintensiven Gesichtserlebnissen, also bei in allen Hinsichten differentieller Phänomenalität gilt der trilineare ReizausdruckL. f. t = Konstante. Für überschwellige Lichtempfindungen gelten keine linearen Ausdrücke; alle aufgestellten sind kompliziert und ziemlich undurchsichtig . Es wird darauf hingewiesen, dass auf dem Gebiete des Gehörssinnes ähnliche Verhältnisse wie auf dem Gebiete des Gesichtes vorliegen.Die einflache Linearität der begrifflichen Reizausdrücke einerseits, wenn sie differentielle, in allen Hinsichten phänomenal minimale Erlebnisse wiedergeben, und andererseits die komplizierte Struktur der Ausdrücke, wenn sie überschwellige Phänomenalitäten wiedergeben, bezeugen, dass hier ein Strukturproblem vorliegt, welches im Zusammenhang mit dem gegenseitigen Verhältnis vom Phänomenalen und Begrifflichen steht. Dieser Problemkomplex wird in dieser Abhandlung zu behandeln versucht.In the field of vision the absolute phenomenal threshold may be expressed by the conceptual linear stimulus equation:L. t = const., respectivelyL. f = const., in whichL denotes the physical brightness intensity of light,t the stimulus duration andf the stimulus area . For the former expression the temporal limits of validity extend from quite short durations up to 100σ i.e. up to duration of apparent momentariness. Correspondingly the validity of the second equation seems to extend barely to area values that appear phenomenally punctual . In case of phenomenally momentary and punctual visual perceptions and of those being phenomenally of minimal brightness,i.e. in case of an in every point differential phenomenality the trilinear equation holds true:L. f. t = const. Concerning the supraliminal visual perceptions no such linear expression is valid. If, however, it would be possible to construct an equation representing the phenomenality of supraliminal visual perceptions, it would be very complicated and of little clarity . It is pointed out, that in the field of audition there exist similar relations as in the field of visual perceptions.The simple linearity of conceptual stimulus equations, when they denote differential, in every respect phenomenally minimal perceptions and on the other hand the complicated structure of expressions corresponding to supraliminal phenomenalities, show, that there exists a structural problem connected with the phenomenal and conceptual field.An attempt is made to settle this complex of problems.Dans le domaine du sens visuel on peut appliquer au seuil phénoménal absolu les expressions d'excitation linéairesL. t = constante, respectivementL. f = constante. Dans ces expressionsL signifie l'intensité lumineuse physique,t le temps de l'excitation etf la surface de l'excitation . Le domaine de la validité du temps de la première expression s'étend d'un temps très court jusqu'à un espace de temps d'env. 100σ c'est-à-dire jusqu'à des périodes de temps qu'on peut encore percevoir comme phénoménalement momentanées. En analogie avec ceci le domaine de validité de la deuxième expression mentionnée semble s'étendre seulement jusqu'à de telles surfaces qui apparaissent encore phénoménalement ponctuelles. Dans les perceptions visuelles phénoménalement momentanées, ponctuelles et d'un minimum d'intensité, par conséquent dans une phénoménalité sous tous les rapports différentielle, on peut appliquer l'expression d'excitation trilinéaireL. f. t = constante. En ce qui concerne les sensations lumineuses dépassant le seuil il n′y a aucunes expressions linéaires pour les rendre; dans le cas oú l'on pourrait en établir, elles sont compliquées . Il est indiqué que dans le domaine du sens de l'ouïe il se présente des conditions analogues que dans le domaine du sens visuel.La linéarité simple des expressions d'excitation applicable aux cas des sensations différentielles, c'est-à-dire des sensations sous tous les rapports phénoménalement minimes, et de l'autre côté, la structure compliquée des expressions, correspondant à des phénoménalités dépassant le seuil, montrent, qu'il est question ici d'un problème de structure qui est associé à la relation réciproque des phénoménalités et des fonctionalités. Dans cet article l'auteur essaie d'élucider ce complexe de problèmes. (shrink)

It is often assumed that the reaction time of a saccade toward visual and/or auditory stimuli reflects the sensitivities of our oculomotor-orienting system to stimulus saliency. Endogenous factors, as well as stimulus-related factors, would also affect the saccadic reaction time. However, it was not clear how these factors interact and to what extent visual and auditory-targeting saccades are accounted for by common mechanisms. The present study examined the effect of, and the interaction between, stimulus saliency and audiovisual spatial congruency on (...) the SRT for visual- and for auditory-target conditions. We also analyzed pre-target pupil size to examine the relationship between saccade preparation and pupil size. Pupil size is considered to reflect arousal states coupling with locus-coeruleus activity during a cognitive task. The main findings were that the pattern of the examined effects on the SRT varied between visual- and auditory-auditory target conditions, the effect of stimulus saliency was significant for the visual-target condition, but not significant for the auditory-target condition, Pupil velocity, not absolute pupil size, was sensitive to task set, and there was a significant correlation between the pre-saccade absolute pupil size and the SRTs for the visual-target condition but not for the auditory-target condition. The discrepancy between target modalities for the effect of pupil velocity and between the absolute pupil size and pupil velocity for the correlation with SRT may imply that the pupil effect for the visual-target condition was caused by a modality-specific link between pupil size modulation and the SC rather than by the LC-NE system. These results support the idea that different threshold mechanisms in the SC may be involved in the initiation of saccades toward visual and auditory targets. (shrink)

The Sparks of Randomness, Henri Atlan's magnum opus, develops his whole philosophy with a highly impressive display of knowledge, wisdom, depth, rigor, and intellectual and moral vigor. Atlan founds an ethics adapted to the new power over life that modern scientific knowledge has given us. He holds that the results of science cannot ground any ethical or political truth whatsoever, while human creative activity and the conquest of knowledge are a double-edged sword. This first volume, Spermatic Knowledge, begins with the (...) Talmudic tale about the prophet Jeremiah's creation of a golem, or artificial man. Atlan shows that the Jewish tradition does not demonize man for creating and changing living things--a charge often leveled at promoters of advanced technologies, like biologists, who are accused of "playing God." To the contrary, man is depicted as being the co-creator of the world. Although Atlan believes that the fabrication of life "from scratch" will take place in the near future, he posits that this achievement will not really amount to creating life current biology and biotechnologies have demonstrated that there is no absolute distinction between life and non-life, no critical threshold whose crossing would be taboo. He also debunks and demystifies our belief in free will and our conviction, of theological origin, that there would be no possibility for ethics if free will were shown to be an illusion. Throughout, he combines science, religion, and ancient and modern philosophy in unexpected and inspired ways. His radical, uncompromising Spinozism allows him to propose a complete revision of cognitive science and philosophy of mind, while showing that their current impasses stem from remnants of traditional dualism. From his brilliant reflections on time, he also derives exciting considerations for medicine and epidemiology. (shrink)

BackgroundMany procedures currently require the use of bone grafts to replace or recover bone volume that has been resorbed. However, the patient’s opinion and preferences must be taken into account before implementing any treatment. Researchers have focused primarily on assessing the effectiveness of bone grafts rather than on patients' perceptions. Thus, the aim of this study was to explore patients' opinions regarding the different types of bone grafts used in dental treatments.MethodsOne hundred patients were randomly chosen participated in the study. (...) A standardized survey of 10 questions was used to investigate their opinions regarding the different types of bone grafts used in dental treatments. Descriptive statistics were calculated for the different variables, and absolute frequencies and percentages were used as summary measures. A value of p <0.05 was selected as the threshold for statistical significance.ResultsThe highest rate of refusal was observed for allografts and xenografts. The grafts with the lowest rates of refusal were autologous grafts and alloplastics. No significant differences were found between the various types of bone grafts in the sociodemographic variables or the refusal/acceptance variable. Similarly, no significant relations were observed between a specific religious affiliation and the acceptance/refusal rates of the various types of graft.ConclusionsAllografts and xenografts elicited the highest refusal rates among the surveyed patients, and autologous bone and alloplastics were the most accepted bone grafts. Moreover, no differences were found in the sociodemographic variables or religious affiliations in terms of the acceptance/refusal rates of the different bone grafts. (shrink)