Irresponsible research practices damaging the value of science has been an increasing concern among researchers, but previous work failed to estimate the prevalence of all forms of irresponsible research behavior. Additionally, these analyses have not included articles published in the last decade from 2011 to 2020. This meta-analysis provides an updated meta-analysis that calculates the pooled estimates of research misconduct and questionable research practices, and explores the factors associated with the prevalence of these issues. The estimates, committing RM concern at (...) least 1 of FFP and QRPs concern 1 or more QRPs, were 2.9% and 12.5%, respectively. In addition, 15.5% of researchers witnessed others who had committed at least 1 RM, while 39.7% were aware of others who had used at least 1 QRP. The results document that response proportion, limited recall period, career level, disciplinary background and locations all affect significantly the prevalence of these issues. This meta-analysis addresses a gap in existing meta-analyses and estimates the prevalence of all forms of RM and QRPs, thus providing a better understanding of irresponsible research behaviors. (shrink)

This paper studies the state of charge estimation of supercapacitors and lithium batteries in the hybrid energy storage system of electric vehicles. According to the energy storage principle of the electric vehicle composite energy storage system, the circuit models of supercapacitors and lithium batteries were established, respectively, and the model parameters were identified online using the recursive least square method and Kalman filtering algorithm. Then, the online estimation of SOC was completed based on the Kalman filtering algorithm and unscented Kalman (...) filtering algorithm. Finally, the experimental platform for SOC estimation was built and Matlab was used for calculation and analysis. The experimental results showed that the SOC estimation results reached a high accuracy, and the variation range of estimation error was [−0.94%, 0.34%]. For lithium batteries, the recursive least square method is combined with the 2RC model to obtain the optimal result, and the estimation error is within the range of [−1.16%, 0.85%] in the case of comprehensive weighing accuracy and calculation amount. Moreover, the system has excellent robustness and high reliability. (shrink)

ObjectivesSeveral studies have examined the effects of repetitive transcranial magnetic stimulation (rTMS) on associative memory (AM) but findings were inconsistent. Here, we aimed to test whether twice-daily rTMS could significantly improve AM.MethodsIn this single-blind, sham-controlled experiment, 40 participants were randomized to receive twice-daily sham or real rTMS sessions for five consecutive days (a total of 16,000 pulses). The stimulation target in left inferior parietal lobule (IPL) exhibiting peak functional connectivity to the left hippocampus was individually defined for each participant. Participants (...) completed both a picture-cued word association task and Stroop test at baseline and 1 day after the final real or sham rTMS session. Effects of twice-daily rTMS on AM and Stroop test performance were compared using two-way repeated measures analysis of variance with main factors Group (real vs. sham) and Time (baseline vs. post-rTMS).ResultsThere was a significant Group × Time interaction effect. AM score was significantly enhanced in the twice-daily real group after rTMS, but this difference could not survive the post hoc analysis after multiple comparison correction. Further, AM improvement in the twice-daily real group was not superior to a previously reported once-daily rTMS group receiving 8,000 pulses. Then, we combined the twice- and once-daily real groups, and found a significant Group × Time interaction effect. Post hoc analysis indicated that the AM score was significantly enhanced in the real group after multiple comparisons correction.ConclusionOur prospective experiment did not show significant rTMS effect on AM, but this effect may become significant if more participants could be recruited as revealed by our retrospective analysis. (shrink)

ObjectiveTwo subregions of the dorsolateral prefrontal cortex have been identified as effective repetitive transcranial magnetic stimulation targets for the “anxiosomatic” and “dysphoric” symptoms, respectively. We aimed to develop a convenient approach to locate these targets on the scalp.Materials and methodsIn a discovery experiment, the two personalized targets were precisely identified on 24 subjects using a neuronavigation system. Then, a localized approach was developed based on individual scalp landmarks. This “landmark-based approach” was replicated and validated in an independent cohort. Reliability of (...) the approach was tested by calculating the correlation of both the inter-rater and intra-rater results. Validity was tested by comparing the mean distance between the personalized and landmark-based targets to the TMS spatial resolution. We further conducted a total of 24 sham rTMS sessions to estimate the misplacement between the coil center and target during a 10-min stimulation without neuronavigation.ResultsThe parameters of the “landmark-based approach” in the discovery experiment were replicated well in an independent cohort. Using discovery parameters, we successfully identified the symptom-specific targets in the independent cohort. Specifically, the mean distance between the personalized and landmark-based targets on the cortex was not significantly larger than 5 mm. However, the personalized and landmark-based targets distance exceeded 5 mm in more than 50% of subjects. During the 10-min sham rTMS session, the average coil misplacement was significantly larger than 5 mm.ConclusionThe “landmark-based approach” can conveniently and reliably locate the two symptom-specific targets at group level. However, the accuracy was highly varied at individual level and further improvement is needed. (shrink)

The increasing importance of computational techniques in post-genomic life science research calls for new forms and combinations of expertise that cut across established disciplinary boundaries between computing and biology. These are most marked in large scale gene sequencing facilities. Here new ways of organising knowledge production, drawing on industrial models, have been perceived as pursuing efficiency and control to the potential detriment of academic autonomy and scientific quality. We explore how these issues are played out in the case of BGI (...) (Beijing Genomics Institute prior to 2008). BGI (in Pinyin, Hua Da Jiyin– Big China Genome) is today the world’s largest centre for gene sequencing research. Semi-detached from traditional academic institutions, BGI has developed distinctive models for organising research and for developing expertise, informed by practices in US Information Technology and Life Science Laboratories, that differ from existing models of interdisciplinary research in academic institutions. (shrink)

ABSTRACT In order to construct a satisfactory theory of cheng-yi 誠意, Zhu Xi 朱熹 develops an account of how self-deception is possible—a profound problem that has puzzled many philosophers. In Zhu’s opinion, zhi 知 can be divided into two categories: a priori knowing and empirical knowing. The further division of empirical knowing defines three sorts of self-deception: the self-deception caused by one’s ignorance, the self-deception caused by one’s superficial knowing, and the self-deception that may occur when one acquires genuine knowledge. (...) In this paper, I will construct a theoretical model of self-deception that follows Zhu’s criterial definition of self-deception in Daxue Zhangju 大學章句, thereby accounting for the possibility of these three sorts of self-deception. Better understanding of Zhu’s conception of self-deception could, moreover, open fruitful avenues for further work on his metaphysics and moral psychology. (shrink)

Constructing a self model with universal cultural adaptability is a common concern of cultural psychologists. These models can be divided into two types: one is the self model based on Western culture, represented by the self theory of Marsh, Cooley, Fitts, etc.; the other is the non-self model based on Eastern culture, represented by the Mandela model of Hwang Kwang Kuo and the Taiji model of Zhen Dong Wang. However, these models do not fully explain the self structure and development (...) of Chinese people in the context of Chinese Buddhist culture. Based on the self theory of Chinese Buddhism and inspired by the famous Buddhist work Awakening of Faith in the Mahāyāna, this article constructs the “one mind, two aspects” self model. This model not only can properly represent the self structure of Chinese people in the context of Chinese Buddhism but also can explain the self-cultivation process and the realm of practice of Chinese Buddhist believers and thus has satisfactory cultural validity. (shrink)

We build a collection of topological Ramsey spaces of trees giving rise to universal inverse limit structures, extending Zheng’s work for the profinite graph to the setting of Fraïssé classes of finite ordered binary relational structures with the Ramsey property. This work is based on the Halpern-Läuchli theorem, but different from the Milliken space of strong subtrees. Based on these topological Ramsey spaces and the work of Huber-Geschke-Kojman on inverse limits of finite ordered graphs, we prove that for each such (...) Fraïssé class, its universal inverse limit structure has finite big Ramsey degrees under finite Baire-measurable colorings. For such Fraïssé classes satisfying free amalgamation as well as finite ordered tournaments and finite partial orders with a linear extension, we characterize the exact big Ramsey degrees. (shrink)

Patients with chronic obstructive pulmonary disease are characterized by attenuated pulmonary function and are frequently reported with cognitive impairments, especially memory impairments. The mechanism underlying the memory impairments still remains unclear. We applied resting-state functional magnetic resonance imaging to compare the brain local activities with static and dynamic amplitude of low-frequency fluctuations among patients with COPD and healthy controls. Compared with HC, COPD patients exhibited decreased sALFF in the right basal ganglia and increased dALFF in the bilateral parahippocampal/hippocampal gyrus. The (...) reduced the left basal ganglia was associated with lower oxygen partial pressure. Besides, the increased dALFF in the left hippocampal/parahippocampal cortex was associated with poor semantic-memory performance and the increased dALFF in the left hippocampal/parahippocampal cortex was associated the forced vital capacity. The present study revealed the abnormal static and dynamic local-neural activities in the basal ganglia and parahippocampal/hippocampal cortex in COPD patient and its relationship with poor lung function and semantic-memory impairments. (shrink)

Female-entrepreneurship plays a significantly important role in rural areas of China today. In fact, it is a driving force behind inclusive economic development of the country as a whole. However, notably very little literature out there has focused on the impact of how widespread usage of information technology tools affects the mothers entrepreneurship in the outskirt regions. Here, in this paper, the authors attempt to explore the finer details of such an impact by utilizing the data from the 2017 China (...) Integrated Social Survey; along with the IV-Probit model to explore the transmission mechanism. Interestingly enough, it was discovered that Internet applications and tools do indeed increase entrepreneurship among women with children by a roughly 7.88%. In addition, this paper finds that the utilization of such “InfoTech” promote a continuous progress in entrepreneurship among those women with children who endeavor to start a self-managed enterprise in the less developed areas. Lastly, when looking the analysis of the transmission mechanism, this paper found that the role of Internet-usage in promoting rural mothers entrepreneurship was mainly through three factors – the gender equality effect, the information learning effect, and the financing effect. This accumulated data will be thoroughly presented here in the ensuing sections. (shrink)

As a global public health concern, elder abuse negatively affects health, psychosocial wellbeing, and mortality among elders. Research and practice efforts made to explore effective prevention and intervention strategies are growing. Despite the growing number of intervention studies on elder abuse, research synthesis on the empirical literature seems lacking. This study aims to identify the pooled effect size of prevention and interventions targeted ultimate and intermediate outcomes for elder abuse that occurred in community settings. Following the Cochrane guideline, our team (...) searched across eight electronic databases and manually searched reference lists of eligible studies and existing systematic reviews for all potentially eligible studies. A random-effects model of 51 effect size estimates reported an overall positive and statistically significant treatment effect of psychosocial interventions for elder abuse, d = 0.63, p < 0.05. The overall treatment effect was approaching statistical significance at 0.1 level for ultimate outcomes, d = 0.32, p = 0.09, and intermediate outcomes, d = 0.75, p = 0.1. An overall significant effect size was found among family-based interventions, d = 0.59, p < 0.05, and interventions targeting older adults and their caregivers, d = 0.45, p < 0.05. Existing evidence supports an overall significant effect for psychosocial interventions for elder abuse. Interventions that used a family-based model, combined education and supportive services, and targeted both caregivers and elders, showed significant effect size, suggesting such features being considered in elder abuse intervention design. Future intervention research is needed to shed light on the link between intervention activities and ultimate change in elder abuse behaviors. (shrink)

Ingratiation is a common strategy for subordinates to deal with their supervisors in eastern and western societies. Based on the theory of impression management, this study focuses on the impact of upward ingratiation outside the workplace on supervisor’s human resource decisions in the Chinese context and the mechanism behind this impact. The data were collected from 252 supervisor-subordinate dyads in four manufacturing firms. The results demonstrate the following: first, supervisors hold a more favorable view of upward ingratiation outside the workplace; (...) second, upward ingratiation outside the workplace has a positive effect on the supervisor’s chance of promotion and bonus allocation decisions, and leader-member exchange plays a mediation role in this influence; third, Zhongyong thinking moderates the relationship between LMX and supervisor’s chance of promotion and bonus allocation decisions; and finally, ZYT moderates the indirect effect of ingratiation behavior outside the workplace on supervisor’s chance of promotion and bonus allocation decisions through LMX, and the mediated relationship is weakened when a supervisor has a higher level of ZYT. This is one of the first empirical studies, which examines the validity of subordinate’s upward ingratiation outside the workplace from the perspective of supervisor’s ZYT. This study plays an important role in highlighting the effect of ZYT on the ingratiation behavior. (shrink)

Exact solutions of epidemic models are critical for identifying the severity and mitigation possibility for epidemics. However, solving complex models can be difficult when interfering conditions from the real-world are incorporated into the models. In this paper, we focus on the generally unsolvable adaptive susceptible-infected-susceptible epidemic model, a typical example of a class of epidemic models that characterize the complex interplays between the virus spread and network structural evolution. We propose two methods based on mean-field approximation, i.e., the first-order mean-field (...) approximation and higher-order mean-field approximation, to derive the exact solutions to ASIS models. Both methods demonstrate the capability of accurately approximating the metastable-state statistics of the model, such as the infection fraction and network density, with low computational cost. These methods are potentially powerful tools in understanding, mitigating, and controlling disease outbreaks and infodemics. (shrink)

Solvency assessment is the core content of insurance supervision. In this paper, from the perspective of capital flow, the insurance company’s capital flow is regarded as a dynamic system, the stochastic differential equations model is established to describe its flow characteristics, and the existence of positive equilibrium point of the system is proved, as well as the conditions of stability at equilibrium point, that is, the requirements of the insurance company’s solvency. Furthermore, by using the numerical simulation method, we get (...) the strategy of insurance companies to deal with the solvency shortage when facing the change of external environment, and the strategy of insurance company to deal with solvency shortage is obtained. (shrink)

In the age of digitalization, social media has played a significant role in quickly spreading the news about current affairs. From December 2019 to now, coronavirus disease 2019, with its several mutated shapes, has more transmissible potential catastrophe and has become a severe phenomenon issue worldwide. The international spread of the epidemic has created fear among people, especially employees working physically in different organizations. The present research aimed to measure the impact of social media on its users in the China. (...) The social media users more often were influenced by shocking news instructively and destructively. The research analysis was based on service sector employees and data collected from 630 respondents via a structured questionnaire. This research was confirmed the negative impact of fear on social media on the performance of employees. This research was also confirmed the moderation impact of the COVID-19 vaccine on the relationship between social media fear and employee performance. This research recommends that the China Censor Board checked the news and its validity to reduce the fear of COVID-19 among employees. This research will become a roadmap for organizations and media controllers to understand the impact of social media during an intense situation. The telecommunication sector will reduce psychological disease and enhance the work capability of employees by controlling unnecessary and unapproved material about sensitive issues. (shrink)

本书立足道德哲学的基点从事苟学研究，取径于德性伦理学（virtue ethics）的理论进路，尝试对荀子的伦理思想做一种传统儒家修身哲学意义上的解读和阐释。.

It is a common aim of psychologists to construct a definition model with universal cultural applicability for mental health. These models can be divided into two types in terms of definition: One is the negative mental health definition model based on the absence of mental illness symptoms; the other is the definition model of positive mental health based on subjective feelings, such as happiness and social identity. However, neither of these definitions can properly explain Chinese people’s understanding of mental health (...) or how mental health is dealt with in Chinese culture. This paper proposes a Yin–Yang definition model of mental health based on the theory of personality of Confucianism and Taoism. This model not only properly describes the understanding of mental health in traditional Chinese culture, but also explains East Asian psychotherapy and mental health practices in the context of Chinese culture. (shrink)

Patients with advanced Alzheimer's disease experience cognitive impairment and physical disabilities in daily life. Currently, there are no treatments available to slow down the course of the disease, and limited treatments exist only to treat symptoms. However, deep brain stimulation of the nucleus basalis of Meynert has been reported to improve cognitive function in individuals with AD. Here, we report the effects of NBM-DBS on cognitive function in a subject with severe AD. An 80-year-old male with severe AD underwent surgery (...) for bilateral NBM-DBS electrode placement. After 10 weeks of stimulation, Mini-Mental State Examination assessment improved from a score of 5 to 9 points, and assessment using the Alzheimer's Disease Assessment Scale–Cognitive Subscale showed a marked reduction in total score from 43 to 33 points, suggesting cognitive benefits from NBM-DBS. The patient's postoperative course was complicated by a subdural effusion that occurred several days after surgery, with complete recovery. Interestingly, the subject also displayed abnormal thermoregulation with stimulation initiation and stimulation parameter modifications. NBM-DBS may serve as a potential therapy for severe AD patients.Clinical Trial Registration: ChiCTR1900022324. (shrink)