Ethical debates around genetic enhancement tend to include an argument that the technology will eventually be fairly accessible once available. That we can fairly distribute genetic enhancement has become a moral defence of genetic enhancement. Two distribution solutions are argued for, the first being equal distribution. Equality of access is generally believed to be the fairest and most just method of distribution. Second, equitable distribution: providing genetic enhancements to reduce social inequalities. In this paper, I make two claims. I first (...) argue that the very assumption that genetic enhancements can be distributed fairly is problematic when considering our understanding of gene–environment interactions, for example, epigenetics. I then argue that arguments that genetic enhancements are permissible because the intended benefits can be distributed fairly as intended are misinformed. My first claim rests on the assertion that genetic enhancements do not enhance traits in a vacuum; genes are dependent on conducive environments for expression. If society cannot guarantee fair environments, then any benefit conferred from being genetically enhanced will be undermined. Thus, any argument that the distribution of genetic enhancements will be fair and that the technology is therefore morally permissible, is mistaken. (shrink)

In her recent article, Prince has identified a critical challenge for those who advocate genetic enhancement to reduce social injustices. The gene–environment interaction prevents genetic enhancement from having equitable effects at the phenotypic level, even if enhancement were available to the entire population. The poor would benefit less than the rich from their improved genes because their genotypes would interact with more unfavourable socioeconomic environments. Therefore, Prince believes that genetic enhancement should not be used to combat social inequalities, (...) since it can likely aggravate them. In this article, I raise various objections to this conclusion. I argue first that genetic enhancement need not necessarily magnify social injustices. I then show that genetic enhancement can play a modest but not insignificant role in the quest for social justice in the future. Finally, I conclude by arguing for the need to consider the complex interplay between the social lottery and the natural lottery in our aspirations for justice linked to genetic technologies. (shrink)

Parents influence the development of their offspring in many ways beyond the transmission of DNA. This includes transfer of epigenetic states, nutrients, antibodies and hormones, and behavioural interactions after birth. While the evolutionary consequences of such nongenetic inheritance are increasingly well understood, less is known about how inheritance mechanisms evolve. Here, we present a simple but versatile model to explore the adaptive evolution of non-genetic inheritance. Our model is based on a switch mechanism that produces alternative phenotypes in response to (...) different inputs, including genes and non-genetic factors transmitted from parents and the environment experienced during development. This framework shows how genetic and non-genetic inheritance mechanisms and environmental conditions can act as cues by carrying correlational information about future selective conditions. Differential use of these cues is manifested as different degrees of genetic, parental or environmental morph determination. We use this framework to evaluate the conditions favouring non-genetic inheritance, as opposed to genetic determination of phenotype or within-generation plasticity, by applying it to two putative examples of adaptive non-genetic inheritance: maternal effects on seed germination in plants and transgenerational phase shift in desert locusts. Our simulation models show how the adaptive value of non-genetic inheritance depends on its mechanism, the pace of environmental change, and life history characteristics. (shrink)

Historically, farmers have been amongst the most innovative people in the world. However, agriculture now lags behind other sectors in its uptake of new information technologies for the control and automation of farming systems. In spite of decades of research into innovation, we still do not have a good understanding as to why this is the case. With the globalisation of food markets, IT adoption in agricultural communities is perceived to be increasingly important by policy makers. As the most marginalised (...) of rural communities, it is self-evident that agricultural communities in less developed countries are most in need of these systems. This paper proposes a new integral systems framework of e-agricultural adoption and innovation in less developed countries. It opens up a new avenue of research for control and automation systems theory and practice, which informs policy in respect of e-readiness of rural communities. (shrink)

Food Deserts have recently beenidentified in the United Kingdom. They havebeen defined by Tessa Jowell, UK GovernmentHealth Minister, as an area ``where people donot have easy access to healthy, fresh foods,particularly if they are poor and have limitedmobility.'' The above definition is particularlyrelevant in Northern Ireland, where it isestimated that 32% of households do not haveeasy access to a car and it is recognized thatcertain groups in Northern Ireland are amongstthe poorest consumers in the United Kingdom.The phenomenon has been further (...) exacerbated bythe effect of large grocery retailers locatingon the periphery of towns and the subsequentdisplacement effect of independent retailers inthe town center. The resultant effect is suchthat disadvantaged consumers cannot accessfresh, quality, nutritious foods at anaffordable price. Preliminary researchindicates that certain consumer groups areexcluded from equitable shopping provision –possibly to the detriment of their healthstatus. Research methodology includes aconsumer questionnaire, consumer focus groups,interviews, and comparative shopping exercisesthat confirm an inability among vulnerableconsumer groups to achieve an affordable,healthy diet. This was further complicated bynon-car owners' and lower-income family unitsneeding to shop locally and more frequentlythan their higher-income, car-ownercounterparts. This was demonstrated with theuse of shopping diaries. Future research to beconducted includes a large-scale survey acrossNorthern Ireland to ascertain accessibility,availability, and affordability of qualityfresh foods and to distinguish the consumergroups who are most vulnerable. (shrink)

Adapting gross motor movement to match the tempo of auditory rhythmic stimulation is a complex skill with a long developmental trajectory. Drumming tasks have previously been employed with infants and young children to measure the emergence of rhythmic entrainment, and may provide a tool for identification of those with atypical rhythm perception and production. Here we describe a new protocol for measuring infant rhythmic movement that can be employed at scale. In the current study, 50 two-year-olds drummed along with the (...) audiovisual presentation of four steady rhythms, using videos of isochronous drumming at 400, 500, 600, and 700 ms IOI, and provided their spontaneous motor tempo by drumming in silence. Toddlers’ drumming is observed from video recordings made in participants’ own homes, obtained via the Lookit platform for online infant studies. We use OpenPose deep-learning model to generate wireframe estimates of hand and body location for each video. The vertical displacement of the hand was extracted, and the power and frequency of infants’ rhythmic entrainment quantified using Fast Fourier Transforms. We find evidence for age-appropriate tempo-flexibility in our sample. Our results demonstrate the feasibility of a fully digital approach to measuring rhythmic entrainment from within the participant’s home, from early in development. (shrink)

By analyzing the feminist debates on Hans-Georg Gadamer, the author shows that feminist critics point to the need either to supplement or to replace Gadamer's philosophy with a greater sensitivity to the historical implications of women's experience. Thus, they are of the view either that Gadamer's philosophy has yet to come to terms with specific historical situations or that Gadamer's philosophy cannot come to terms with historical situatedness per se. The author contends that Gadamer's femi-nist critics do not locate the (...) source of his residual transcendentalism where it should be located: in the account of aesthetic judgment as a "pure feeling" that underpins his entire philosophy. This has the effect, of appearing to preserve aesthetic judgment as "pure feeling" as an apparently innocent remedy, to which some of his feminist critics actually appeal in opposition to his transcendentalism. The author argues, to the contrary, that aesthetic judgment, as a "pure feeling," is at once too com-plicit in the tradition that feminists seek to engage with, traditionally too insubstantial to make a rich resource for a feminist critique of that tradition, and ultimately too traditionally male-centered to be easily coopted by a feminist philosopher. (shrink)

This essay addresses the relationship between home, belonging and the maternal in feminist theory and fiction. Feminist discourse isoften typified by its critique of home: analysing the gendered assumptions underlying the depiction of home as nurturing, or exposing the regressive and essentialist connotations of the search for safe homes. A number of recent feminist theorists (Probyn, Bammer, Young) have, however, pointed to thepersistence of ‘retrograde’ desires for safety and belonging, particularly in an era of widespread dislocations. At the same time, (...) feminist critics such as Roberta Rubenstein have re-invoked the contested relationship between home and the maternal by arguing that the desire for home speaks to our earliest needs for security: a desire that ultimately maps on to a longing for the (idealized) mother as the ‘original safe home’ (Rubenstein, 2001). This essay draws upon the work of Rubenstein, Bammer and Young in order to examine the relationship between home and the maternal in a recent Irish novel, Mary Morrissy’s Mother of Pearl. The plot of this novel, dealing with the events surrounding an incident of baby snatching, suggests both the persistence of (the maternal) home as a desire and the impossibility of identifying an original or authentic maternal/home. By exploring how the protagonists of this novel negotiate the demands and appeals of home and motherhood, this essay will ask to what extent it may be possible for feminism to recuperate, or re-envision, the maternal/home as utopian ideal. (shrink)

Self‐care, or self‐management, is presented in healthcare policy as a precursor to patient empowerment and improved patient outcomes. Alternatively, critiques of the self‐care agenda suggest that it represents an over‐reliance on individual autonomy and responsibility, without adequate support, whereby ‘self‐care’ is potentially unachievable and becomes ‘care left undone’. In this sense, self‐care contributes to a blame culture where ill‐health is attributed to personal behaviours or lack thereof. Furthermore, self‐care may represent a covert form of rationing, as the fiscal means to (...) enable effective self‐care and supplement, or replace, self‐care capacities, is not provided. This paper explores these arguments through a contemporary ethical analysis of the self‐care agenda. The terms self‐care and self‐management are used interchangeably throughout whereby self‐management is understood as a point in the wider self‐care continuum. (shrink)

Many languages have past-and-counterfactuality markers such as English simple past. There have been various attempts to find a common definition for both uses, but I will argue in this paper that they all have problems with ruling out unacceptable interpretations, or accounting for the contrary-to-fact implicature of counterfactual conditionals, or predicting the observed cross-linguistic variation, or a combination thereof. By combining insights from two basic lines of reasoning, I will propose a simple and transparent approach that solves all the observed (...) problems and offers a new understanding of the concept of counterfactuality. (shrink)

In his Wittgenstein on Rules and Private Language , Saul Kripke presents his influential reading of Wittgenstein’s later writings on language. One of the largely unexplored features of that reading is that Kripke makes a small number of suggestive remarks concerning the possible threat that Wittgenstein’s arguments pose for Chomsky’s linguistic project. In this paper, we attempt to characterise the relevance of Wittgenstein’s later work on meaning and rule-following for transformational linguistics, and in particular to identify the potentially negative impact (...) it has on that project. Although we use Kripke’s remarks to articulate some of the pertinent issues, we return to Wittgenstein’s later writings to address them. We argue that Wittgenstein’s main target in the relevant sections of the Philosophical Investigations is the notion of ‘logical compulsion’, which involves assuming that there is more to applying a word or rule than how we are naturally or “psychologically” compelled to apply. We characterise two of the main lines of argument in the Investigations in terms of the rejection of logical compulsion. We thus propose to address the relevance of Wittgenstein’s writings for Chomsky by considering whether Chomsky’s linguistics presupposes the targeted notion of logical compulsion. We argue that Chomsky’s conception of linguistic competence in terms of successive states of the “language faculty” (containing the principles of universal grammar) does presuppose this problematic notion. Chomsky responded to Kripke by devoting a chapter of his Knowledge of Language to defending this conception of linguistic competence against the Wittgensteinian arguments. We evaluate his response and argue that he has misidentified the threat to his linguistic project as consisting in the attack on its ‘individual psychology’ standpoint, rather than its commitment to logical compulsion. We conclude by arguing that Chomsky’s attempts at defending his individualist or non-communitarian standpoint are undermined by his inability to give a decisive response to Wittgenstein’s attack on logical compulsion. (shrink)

Across the world, artificial intelligence (AI) technologies are being more widely employed in public sector decision-making and processes as a supposedly neutral and an efficient method for optimizing delivery of services. However, the deployment of these technologies has also prompted investigation into the potentially unanticipated consequences of their introduction, to both positive and negative ends. This paper chooses to focus specifically on the relationship between gender bias and AI, exploring claims of the neutrality of such technologies and how its understanding (...) of bias could influence policy and outcomes. Building on a rich seam of literature from both technological and sociological fields, this article constructs an original framework through which to analyse both the perpetuation and mitigation of gender biases, choosing to categorize AI technologies based on whether their input is text or images. Through the close analysis and pairing of four case studies, the paper thus unites two often disparate approaches to the investigation of bias in technology, revealing the large and varied potential for AI to echo and even amplify existing human bias, while acknowledging the important role AI itself can play in reducing or reversing these effects. The conclusion calls for further collaboration between scholars from the worlds of technology, gender studies and public policy in fully exploring algorithmic accountability as well as in accurately and transparently exploring the potential consequences of the introduction of AI technologies. (shrink)

In her chapter “Duress and Moral Progress”, Seana Shiffrin offers a novel perspective on coerced promises. According to the dominant view, these promises confer no right to performance on the coercer and do not create new reasons for the victim. Shiffrin accepts that these promises fail to confer rights, but disagrees that they never alter the victim’s moral profile. She argues that they do at least where promises are ‘initiated’ by the victim, rather than ‘dictated’ by the coercer. The initiation (...) of a promise, albeit in far from ideal circumstances, opens the door, Shiffrin claims, to valuable opportunities for moral progress. In this response, I argue that Shiffrin makes a misstep by not rejecting the dominant view altogether. I suggest that the older Hobbesian picture, according to which coerced promises do confer rights, is supported by our moral and legal practices. Furthermore, it makes moral progress more likely. (shrink)

Antisthenes was famous in antiquity for his studies of Homer's poems, his affiliation with Gorgias and the sophistic movement, his pure Attic writing style, and his inspiration of Diogenes of Sinope, who founded the Cynic philosophical movement. Antisthenes stands at two of the greatest turning points in ancient intellectual history: from pre-Socraticism to Socraticism, and from classical Athens to the Hellenistic period. Antisthenes' works form the path to a better understanding of the intellectual culture of Athens that shaped Plato and (...) laid the foundations for Hellenistic philosophy and literature. Antisthenes of Athens keeps in mind the goals and polemics framing each philosophical and textual discussion. The volume considers the ancient traditions about Antisthenes' rejection of Plato's “Theory of Forms,” his assertion of the paradox, “It is impossible to gainsay,” and his denial that definition of essence is possible, as well as the plausible intentions of Antisthenes. In cases where these questions are not easily settled, and where modern interpretation has varied, Susan H. Prince identifies the roots of the disagreements. The goal and meaning of Antisthenes' other famous ancient paradox, “I would rather go mad than have pleasure,” is illuminated by comparison with other evidence showing that pleasure does have a place in his ideology. Evidence for his relationship to Diogenes of Sinope, and for his receptions by the Cynics, Stoics, Skeptics, Christians, and Neo-Pagans is examined for both its historical value and its distorting tendencies. (shrink)

The autonomous right of competent adults to decide what happens to their own body and the corresponding right to consent to or refuse medical treatment are cornerstones of modern health care. For minors the situation is not so clear cut. Since the well-known case of Gillick, mature children under the age of 16 can agree to proposed medical treatment. However, those under the age of 18 do not enjoy any corresponding right to refuse medical treatment. Can this separation of the (...) right to agree to treatment and the right to refuse treatment for those under 18, regardless of capacity, be justified? This paper evaluates the key cases in this area of the law. Changes to the current law are then proposed which aim to make the law more consistent and reasonable. (shrink)

Paul uses the word ἑνότης twice in Ephesians, and quite strangely, those are the only two places where the feminine noun features in the whole of the New Testament. In the two passages where they appear, they both relate to invisible unity, the unity of the Spirit that produces a common faith and knowledge of the Son of God – εἰς τὴν ἑνότητα τῆς πίστεως καὶ τῆς ἐπιγνώσεως τοῦ υἱοῦ τοῦ Θεοῦ. Such unity suggests that ecumenism amongst Christian denominations is (...) not only a possibility, it is also a necessity as far as we all profess one Christ. This unity is however far from ecclesiological unionism. Considering that the church appears weak from the outside when its diverse lines of doctrine, sacraments and ministerial ethics are emphasised. This suggests that a reasonable antidote would be the emphasis on the philosophy of unity amidst our diversity especially to the hearing of non-Christians.Contribution: This study makes firm the belief that Christianity is formed on divergent traditions that produced various strands of practices, which in turn produce different Christian sects and denominations, and a reverse is not possible. It then suggests a bonding in faith through the invisibility of henotic unity, which the pericope suggests. This will help the church to amass a stronger defence politically and structurally against rival religions and social organisations even in the midst of doctrinal differences. (shrink)

The modern use of the word ‘persecution’ in both speeches and books shows a phenomenon that is almost wholly associated with religion. However, persecution is a threat to the peace of religious institutions as well as various societies all over the world; thus, this makes it a phenomenon beyond the scope of religion. However, this research focuses on religious persecution. It studies an aspect of persecution which is called intra muros persecution. This means ‘internal’ persecution. ‘Internal’ in this context describes (...) the kind that existed in the Jewish religious settings, amongst professing Jews, strictly between Rabbinic Jews and Messianic Jews as predicted in Matthew 10:16–23 and is reflected in today’s Christianity in the form of various intra-denominational attacks in Nigeria. The study delves into the history of events which took place between Rabbinic Jews and Messianic Jews and how it relates to the Christian faith, coming out with the discovery that division which it called sectarianism was the brain behind this brand of persecution. The application of the study to the Nigerian situation necessitates the call for tolerance amongst various denominational sects in Nigeria. (shrink)

The growing practice of returning individual results to research participants has revealed a variety of interpretations of the multiple and sometimes conflicting duties that researchers may owe to participants. One particularly difficult question is the nature and extent of a researcher’s duty to facilitate a participant’s follow-up clinical care by placing research results in the participant’s medical record. The question is especially difficult in the context of genomic research. Some recent genomic research studies — enrolling patients as participants — boldly (...) address the question with protocols dictating that researchers place research results directly into study participants’ existing medical records, without participant consent. Such privileging of researcher judgment over participant choice may be motivated by a desire to discharge a duty that researchers perceive themselves as owing to participants. However, the underlying ethical, professional, legal, and regulatory duties that would compel or justify this action have not been fully explored. (shrink)

We hypothesize that heritable epigenetic changes can affect rates of fitness increase as well as patterns of genotypic and phenotypic change during adaptation. In particular, we suggest that when natural selection acts on pure epigenetic variation in addition to genetic variation, populations adapt faster, and adaptive phenotypes can arise before any genetic changes. This may make it difficult to reconcile the timing of adaptive events detected using conventional population genetics tools based on DNA sequence data with environmental drivers of adaptation, (...) such as changes in climate. Epigenetic modifications are frequently associated with somatic cell differentiation, but recently epigenetic changes have been found that can be transmitted over many generations. Here, we show how the interplay of these heritable epigenetic changes with genetic changes can affect adaptive evolution, and how epigenetic changes affect the signature of selection in the genetic record. (shrink)

There is a prevailing notion amongst preachers of the gospel, especially those in the Pentecostal circle, that adultery is a demonic problem. Their understanding of Jesus' statement in Matthew 5:27-30 about adultery in the heart is that for adultery to happen in an invisible entity such as the heart, some invisible forces (demons) are responsible. This research is an exegetical study of Matthew 5:27-30, employing historical criticism as methodology, to ascertain the correctness of this understanding. The conclusion of this study (...) is that adultery as described and understood in Matthew 5:27-30 is a sexual disorder and not a demonic problem. CONTRIBUTION: This contribution argues that adultery mentioned in Matthew 5:27-30, contrary to its understanding in Pentecostal circles, is a sexual disorder and not the result of demonic spirits that feed the mind with sexual thoughts. (shrink)

The growing practice of returning individual results to research participants has revealed a variety of interpretations of the multiple and sometimes conflicting duties that researchers may owe to participants. One particularly difficult question is the nature and extent of a researcher’s duty to facilitate a participant’s follow-up clinical care by placing research results in the participant’s medical record. The question is especially difficult in the context of genomic research. Some recent genomic research studies — enrolling patients as participants — boldly (...) address the question with protocols dictating that researchers place research results directly into study participants’ existing medical records, without participant consent. Such privileging of researcher judgment over participant choice may be motivated by a desire to discharge a duty that researchers perceive themselves as owing to participants. However, the underlying ethical, professional, legal, and regulatory duties that would compel or justify this action have not been fully explored. (shrink)

L’exercice artistique suppose un rapport au temps spécifique : l’homme s’exerçant à son art répète, reprend, corrige ses gestes. Mais en va-t-il de même concernant la réception des œuvres : la perception du spectateur s’exerce-t-elle par répétition et variation des expériences esthétiques? L’objet de cet article est de montrer qu’il existe un type d’exercice dont le mécanisme repose plutôt sur la déstabilisation des habitudes de perception. À partir des réflexions valéryennes sur l’informe dans l’Introduction à la méthode de Léonard de (...) Vinci et Degas, Danse, Dessin, nous proposons de penser un exercice de la perception qui passe par la décomposition de ses mécanismes. Cette idée trouve sa réalisation dans des dispositifs artistiques labyrinthiques tels que l’exposition Contact d’Olafur Eliasson (Fondation Louis Vuitton, 2014-2015) qui, en perturbant les échelles d’espace et de temps, oblige le récepteur à produire consciemment le travail de cohérence de la synthèse perceptive. (shrink)

L’exercice artistique suppose un rapport au temps spécifique : l’homme s’exerçant à son art répète, reprend, corrige ses gestes. Mais en va-t-il de même concernant la réception des œuvres : la perception du spectateur s’exerce-t-elle par répétition et variation des expériences esthétiques? L’objet de cet article est de montrer qu’il existe un type d’exercice dont le mécanisme repose plutôt sur la déstabilisation des habitudes de perception. À partir des réflexions valéryennes sur l’informe dans l’Introduction à la méthode de Léonard de (...) Vinci et Degas, Danse, Dessin, nous proposons de penser un exercice de la perception qui passe par la décomposition de ses mécanismes. Cette idée trouve sa réalisation dans des dispositifs artistiques labyrinthiques tels que l’exposition Contact d’Olafur Eliasson qui, en perturbant les échelles d’espace et de temps, oblige le récepteur à produire consciemment le travail de cohérence de la synthèse perceptive. (shrink)

L’exercice artistique suppose un rapport au temps spécifique : l’homme s’exerçant à son art répète, reprend, corrige ses gestes. Mais en va-t-il de même concernant la réception des œuvres : la perception du spectateur s’exerce-t-elle par répétition et variation des expériences esthétiques? L’objet de cet article est de montrer qu’il existe un type d’exercice dont le mécanisme repose plutôt sur la déstabilisation des habitudes de perception. À partir des réflexions valéryennes sur l’informe dans l’_Introduction à la méthode de Léonard de (...) Vinci_ et _Degas, Danse, Dessin_, nous proposons de penser un exercice de la perception qui passe par la décomposition de ses mécanismes. Cette idée trouve sa réalisation dans des dispositifs artistiques labyrinthiques tels que l’exposition _Contact_ d’Olafur Eliasson qui, en perturbant les échelles d’espace et de temps, oblige le récepteur à produire consciemment le travail de cohérence de la synthèse perceptive. (shrink)

Reading fiction for pleasurable is robustly correlated with improved cognitive attainment and other benefits. It is also in decline among young people in developed nations, in part because of competition from moving image fiction. We review existing research on the differences between reading/hearing verbal fiction and watching moving image fiction, as well as looking more broadly at research on image/text interactions and visual versus verbal processing. We conclude that verbal narrative generates more diverse responses than moving image narrative., We note (...) that reading and viewing narrative are different tasks, with different cognitive loads. Viewing moving image narrative mostly involves visual processing with some working memory engagement, whereas reading narrative involves verbal processing, visual imagery and personal memory (Xu et al 2005). but Attempts to compare the two by creating suggest that existing research is flawed by attempts to create equivalent stimuli and task demands face a number of challenges, and we discuss these difficulties in comparative approaches. We then investigate the possibility of identifying lower level processing mechanisms that might distinguish cognition of the two media, and propose a focus on internal scene construction and on working memory as foci for future research. Although many of the sources we draw on are focussed on English speaking participants in European or North American settings, we also cover material relating to speakers of Dutch, German, Hebrew and Japanese in their respective countries, and studies of a remote Turkish mountain community. (shrink)