Cognitive deficits are part of the normal aging process and are exacerbated by various diseases that affect adults in old age, such as dementia, depression, and stroke. A significant scientific and social effort has been expended to evaluate whether cognitive deficits can be remedied through systematic interventions. The editors, as well as the chapter authors, represent a variety of viewpoints that span theory as well as practice. Overall, they aim to address concepts in cognitive rehabilitation that are useful in intervention (...) research -- research which examines problems and issues in normal and pathological aging -- and focusing on the application of cognitive training strategies in natural settings. Thus, the book is grounded in contemporary theory in cognitive aging and is applicable to both the practicing clinician as well as the researcher. It is organized into four sections. The first highlights prominent theoretical principles; the second looks at cognitive rehabilitation strategies in normal aging; the third examines the interplay between lifestyle patterns and cognitive function through applying a broad definition of lifestyle choices; and the fourth focuses on rehabilitation strategies that address issues in pathological aging. (shrink)

The gastrointestinal tract is an asymmetrically patterned organ system. The signals which initiate left‐right asymmetry in the developing embryo have been extensively studied, but the downstream steps required to confer asymmetric morphogenesis on the gut organ primordia are less well understood. In this paper we outline key findings on the tissue mechanics underlying gut asymmetry, across a range of species, and use these to synthesise a conserved model for asymmetric gut morphogenesis. We also discuss the importance of correct establishment of (...) left‐right asymmetry for gut development and the consequences of perturbations in this process. (shrink)

This article argues that by using theories of the spatial to understand how situated materiality (i.e., place) and contestations of identity matter when conceiving global and curricular space, educators may interrupt and rearticulate practices and systems of oppression. By focusing on globalization writ large, there is danger of leaving important concerns of the local unattended, and thereby failing to see how processes of globalization exacerbate problematic and oft-hidden curricular issues. Such diversions typify the most insidious quality of the current form (...) of globalization; that is: an articulation of ubiquitous, uniform, and systemically oppressive social scripts. Through the contestation of such scripts, this article focuses on the achievement of better spaces when gender and race are involved. We offer a discussion of curriculum where students write about and argue against the dominant representations of their lives in Washington, DC. Concluding meditations stress that a new conceptual frame is needed in everyday curriculum theorizing, one that enables a reconstruction of curriculum theorists' positionalities with regard to our support, or rerouting, of the scripts that enable globalized systems of oppression and occlusion. (shrink)

For the first time in English, this anthology offers a comprehensive selection of primary sources in the history of philosophy of language. Beginning with a detailed introduction contextualizing the subject, the editors draw out recurring themes, including the origin of language, the role of nature and convention in fixing form and meaning, language acquisition, ideal languages, varieties of meanings, language as a tool, and the nexus of language and thought, linking them to representative texts. The handbook moves on to offer (...) seminal contributions from philosophers ranging from the pre-Socratics up to John Stuart Mill, preceding each major historical section with its own introductory assessment. With all of the most relevant primary texts on the philosophy of language included, covering well over two millennia, this judicious, and generous, selection of source material will be an indispensable research tool for historians of philosophy, as well as for philosophers of language, in the twenty-first century. A vital tool for researchers and contemporary philosophers, it will be a touchstone for much further research, with coverage of a long and varied tradition that will benefit today's scholars and enhance their awareness of earlier contributions to the field. (shrink)

Researchers from across the social sciences have found consistent deviations from the predictions of the canonical model of self-interest in hundreds of experiments from around the world. This research, however, cannot determine whether the uniformity results from universal patterns of human behavior or from the limited cultural variation available among the university students used in virtually all prior experimental work. To address this, we undertook a cross-cultural study of behavior in ultimatum, public goods, and dictator games in a range of (...) small-scale societies exhibiting a wide variety of economic and cultural conditions. We found, first, that the canonical model – based on self-interest – fails in all of the societies studied. Second, our data reveal substantially more behavioral variability across social groups than has been found in previous research. Third, group-level differences in economic organization and the structure of social interactions explain a substantial portion of the behavioral variation across societies: the higher the degree of market integration and the higher the payoffs to cooperation in everyday life, the greater the level of prosociality expressed in experimental games. Fourth, the available individual-level economic and demographic variables do not consistently explain game behavior, either within or across groups. Fifth, in many cases experimental play appears to reflect the common interactional patterns of everyday life. Key Words: altruism; cooperation; cross-cultural research; experimental economics; game theory; ultimatum game; public goods game; self-interest. (shrink)

In the professions of today are ethical concerns of no overwhelming importance? Are these concerns less important in certain professions rather than others? Do some practitioners carry a blase attitude regarding ethics within their profession?This study, sometimes asking life-blood, career-jeopardizing questions is less interested in electronic data results and more interested in actual respondent replies on dissent and competence.

We would like to thank the commentators for their generous comments, valuable insights and helpful suggestions. We begin this response by discussing the selfishness axiom and the importance of the preferences, beliefs, and constraints framework as a way of modeling some of the proximate influences on human behavior. Next, we broaden the discussion to ultimate-level (that is evolutionary) explanations, where we review and clarify gene-culture coevolutionary theory, and then tackle the possibility that evolutionary approaches that exclude culture might be sufficient (...) to explain the data. Finally, we consider various methodological and epistemological concerns expressed by our commentators. (shrink)

How, and how well, do people switch between exploration and exploitation to search for and accumulate resources? We study the decision processes underlying such exploration/exploitation trade‐offs using a novel card selection task that captures the common situation of searching among multiple resources (e.g., jobs) that can be exploited without depleting. With experience, participants learn to switch appropriately between exploration and exploitation and approach optimal performance. We model participants' behavior on this task with random, threshold, and sampling strategies, and find that (...) a linear decreasing threshold rule best fits participants' results. Further evidence that participants use decreasing threshold‐based strategies comes from reaction time differences between exploration and exploitation; however, participants themselves report non‐decreasing thresholds. Decreasing threshold strategies that “front‐load” exploration and switch quickly to exploitation are particularly effective in resource accumulation tasks, in contrast to optimal stopping problems like the Secretary Problem requiring longer exploration. (shrink)

This article is the lead piece in a special report that presents the results of a bioethical investigation into chimeric research, which involves the insertion of human cells into nonhuman animals and nonhuman animal embryos, including into their brains. Rapid scientific developments in this field may advance knowledge and could lead to new therapies for humans. They also reveal the conceptual, ethical, and procedural limitations of existing ethics guidance for human‐nonhuman chimeric research. Led by bioethics researchers working closely with an (...) interdisciplinary work group, the investigation focused on generating conceptual clarity and identifying improvements to governance approaches, with the goal of helping scholars, funders, scientists, institutional leaders, and oversight bodies (embryonic stem cell research oversight [ESCRO] committees and institutional animal care and use committees [IACUCs]) deliver principled and trustworthy oversight of this area of science. The article, which focuses on human‐nonhuman animal chimeric research that is stem cell based, identifies key ethical issues in and offers ten recommendations regarding the ethics and oversight of this research. Turning from bioethics’ previous focus on human‐centered questions about the ethics of “humanization” and this research's potential impact on concepts like human dignity, this article emphasizes the importance of nonhuman animal welfare concerns in chimeric research and argues for less‐siloed governance and oversight and more‐comprehensive public communication. (shrink)

There has recently been a considerable amount of research into the influence of 18th century British philosophy--particularly into the thinking of David Hume on Continental philosophy and Kant. The aim of this collection is to provide some of the key texts which illustrate the impact of Kant's thought together with two important 20th century monographs on aspects of Kant's early reception and his influence on philosophical thought. Contents: Immanuel Kant in England 1793-1838 [1931] Rene Wellek 328 pp The Early Reception (...) of Kant's Thought in England 1785-1805 [1990] Giuseppe Micheli 114 pp A General and Introductory view of Professor Kant's Principles [1796] F. A. Nitsch 234 pp Text-Book to Kant [1881] (with a biographical sketch) James Hutchison Stirling 576 pp The Development from Kant to Hegel [1882] Andrew Seth 178 pp Lectures on the Philosophy of Kant [1890] Thomas Hill Green 155 pp On the Philosophy of Kant [1879] Robert Adamson 270pp A Sketch of Kant's Life and Writings [1854] H. G. Henderson 80 pp Inquisitio Philosophica [1866], An Examination on the Principles of Kant and Hamilton M. P. W. Bolton 286 pp Philosophy of the Unconditioned [1829] William Hamilton 38 pp On the Philosophy of Kant [1856] Henry L. Mansel 45 pp The aim of this collection is to provide some of the key texts which illustrate the impact of Kant's thought together with two important 20th century monographs on aspects of Kant's early reception and his influence on philosophical thought. (shrink)

Criticism of court decisions is a favored American pastime. Typically, such criticisms are grounded in extra-legal criteria such as common sense (or lack of it) and morality (or immorality). Thus Tennessee Valley Authority v. Hill (1978) in which the Supreme Court halted the construction of the nearly completed Tellico Dam because it endangered the habitat of the snail darter, an action forbidden by the Endangered Species Act, was said to confound common sense; and many have called immoral Roe v. Wade (...) (1973) which said the right to abortion, at least through the first trimester, was constitutionally guaranteed. 1 However, even if such criticisms are justified, they do not address the legal issue, which is whether the court got the law wrong. (shrink)

In this paper I develop a theological account of intrinsic value drawn from some passages in Robert Merrihew Adams’ book Finite and Infinite Goods. First I explain why Adams’ work on this topic is interesting, situate his theory within the broader literature on intrinsic value, and draw attention to some of its revisionist features. Next I state the theory, raise some problems for it, and refine it in light of those problems. Then I illustrate how the refined theory works (...) by showing that it has the resources to deal with some seemingly formidable objections. (shrink)